CN114129457A - Moisturizing antioxidant freckle-removing cream and preparation method thereof - Google Patents

Moisturizing antioxidant freckle-removing cream and preparation method thereof Download PDF

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CN114129457A
CN114129457A CN202111534876.0A CN202111534876A CN114129457A CN 114129457 A CN114129457 A CN 114129457A CN 202111534876 A CN202111534876 A CN 202111534876A CN 114129457 A CN114129457 A CN 114129457A
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freckle
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removing cream
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陈小群
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14Liposomes; Vesicles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26Optical properties
    • A61K2800/262Transparent; Translucent

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Abstract

The invention relates to cosmetics and the manufacturing field thereof, and relates to a moisturizing antioxidant freckle-removing cream and a preparation method thereof, wherein the moisturizing antioxidant freckle-removing cream comprises the following components: water, propylene glycol, 1, 2-butylene glycol, squalane, alpha-arbutin, glycerol, polyglycerol-10 oleate, isopropyl palmitate, cetearyl glucoside, glyceryl stearate, cetearyl alcohol, licorice extract, polygonum cuspidatum extract, vitamin E, carbomer, phenylethyl resorcinol, glycyrrhiza glabra extract, allantoin, polyglutamic acid, ethylhexyl glycerol, coenzyme a, phenoxyethanol, arginine, and mint extract. The lipoid and skin care product composition has good whitening and freckle removing effects, is beneficial to increasing the skin elasticity and the water content of the horny layer, has a simple preparation process, and is suitable for industrial large-scale production.

Description

Moisturizing antioxidant freckle-removing cream and preparation method thereof
Technical Field
The invention relates to the field of cosmetics and preparation thereof, in particular to moisturizing, antioxidant and freckle-removing cream and a preparation method thereof.
Background
The freckle-removing cream is an emulsified cream for skin, which has certain inhibition, dissolving and removing effects on certain freckles (such as liver spots, freckles, senile plaques and the like) on the surface of the skin. The formation of color spots is the result of pigmentation on the skin under the influence of factors such as ultraviolet rays, hormones, heredity, aging and the like, so the products mainly achieve the aim of removing the spots by adding effective components for inhibiting and reducing melanin into a cream matrix, and commonly used spot removing additives comprise arbutin, kojic acid, vitamin C derivatives, tartaric acid, traditional Chinese medicine extracts and the like.
The mercury can be absorbed by skin and accumulated in body, and long-term use of the cosmetic containing mercury can cause chronic poisoning and damage organs such as kidney. The long-term use of cosmetics containing glucocorticoids can cause the consequences of facial skin such as black spots, atrophy and thinning, and the like, and can also cause the problems of hormone-dependent dermatitis and the like.
Whitening products have a strong market demand in the asian cosmetics sector because of the problems of skin pigmentation, dull or dark yellow complexion, lack of radiance and susceptibility to allergies prevalent in yellow human skin. In addition, researches show that the skin of most Chinese women is mixed type skin, the phenomenon of uneven skin color is prominent, and the skin has higher double requirements on moisture retention and oil control. Therefore, how to develop a whitening formula which has good whitening effect and small irritation to skin and can also enable whitening active ingredients to be stably dissolved in a water phase so as to avoid the phenomenon that the skin is burdened due to greasy products is always a technical problem in the field.
Whether a whitening active ingredient can control melanin production and deposition during the development of a whitening agent is a technical concern in the art. Most products on the market control the synthesis amount of melanin and realize whitening effect by inhibiting the activity of black synthase (such as tyrosinase, dopachrome tautomerase and the like). Common whitening components such as beta-arbutin, kojic acid, vitamin C derivatives, licorice extract, peony root extract and other traditional Chinese medicine extracts have the effects. However, it has unsatisfactory whitening efficacy, slow whitening speed, and poor inhibitory effect on tyrosinase. Other whitening preparations containing mercury, lead and hydroquinone have strong whitening function, but have great skin irritation and large amount of toxin accumulation on skin, and are easy to cause facial cell necrosis and even generate side effects such as renal dysfunction after long-term use. Therefore, the safety of whitening products is also a concern in the art.
Disclosure of Invention
The invention aims to provide a moisturizing antioxidant freckle-removing cream which solves the problems that in the prior art, a whitening preparation containing mercury, lead and hydroquinone has a strong whitening function, but has great skin irritation, and simultaneously causes a large amount of toxins to skin, so that facial cells are easy to necrose after long-term use, and even side effects such as renal dysfunction are generated.
The invention also aims to provide a preparation method of the moisturizing, anti-oxidation and freckle-removing cream.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
On the one hand, the embodiment of the application provides a moisturizing antioxidant freckle-removing cream, and the freckle-removing cream comprises the following components: water, propylene glycol, 1, 2-butylene glycol, squalane, alpha-arbutin, glycerol, polyglycerol-10 oleate, isopropyl palmitate, cetearyl glucoside, glyceryl stearate, cetearyl alcohol, licorice extract, polygonum cuspidatum extract, vitamin E, carbomer, phenylethyl resorcinol, glycyrrhiza glabra extract, allantoin, polyglutamic acid, ethylhexyl glycerol, coenzyme a, phenoxyethanol, arginine, mint extract, and sodium hyaluronate.
In some embodiments of the present invention, the spot removing cream comprises the following specific components by mass: 68-72 parts of water, 3-5 parts of propylene glycol, 3-5 parts of 1, 2-butanediol, 3-5 parts of squalane, 3-5 parts of alpha-arbutin, 2-5 parts of glycerol, 2-5 parts of polyglycerol-10 oleate, 2-5 parts of isopropyl palmitate, 2-5 parts of cetearyl glucoside, 2-5 parts of glycerol stearate, 2-5 parts of cetearyl alcohol, 2-5 parts of licorice extract, 2-5 parts of polygonum cuspidatum extract, 0.5-1 part of tocopherol, 0.5-1 part of carbomer, 0.5-1 part of phenethyl resorcinol, 0.5-1 part of glycyrrhiza glabra extract, 0.2-0.5 part of allantoin, 0.2-0.5 part of polyglutamic acid, 0.2-0.5 part of ethylhexyl glycerol, 0.2-0.35 part of coenzyme A, 0.2-0.5 part of phenoxyethanol, 0.5 part of beta-methyl pyrrolidone, and the like, 0.2 to 0.5 portion of arginine, 0.05 to 0.2 portion of mint extract and 0.05 to 0.2 portion of sodium hyaluronate.
In some embodiments of the present invention, the specific components of the speckle removing cream include, by mass, 68 parts of water, 3 parts of propylene glycol, 3 parts of 1, 2-butylene glycol, 3 parts of squalane, 3 parts of α -arbutin, 2 parts of glycerol, 2 parts of polyglycerol-10 oleate, 2 parts of isopropyl palmitate, 2 parts of cetearyl glucoside, 2 parts of glycerol stearate, 2 parts of cetearyl alcohol, 2 parts of licorice extract, 2 parts of polygonum cuspidatum extract, 0.5 part of tocopherol, 0.5 part of carbomer, 0.5 part of phenylethyl resorcinol, 0.5 part of glycyrrhiza glabra extract, 0.2 part of allantoin, 0.2 part of polyglutamic acid, 0.2 part of ethylhexyl glycerol, 0.2 part of coenzyme a, 0.2 part of phenoxyethanol, 0.2 part of arginine, 0.05 part of mint extract, and 0.5 part of sodium hyaluronate.
In some embodiments of the present invention, the speckle removing cream is divided into Phase a and Phase B.
In some embodiments of the present invention, Phase a is: water, propylene glycol, 1, 2-butylene glycol, squalane, alpha-arbutin, glycerol, polyglycerol-10 oleate, isopropyl palmitate, cetearyl glucoside, glyceryl stearate and cetearyl alcohol.
In some embodiments of the present invention, Phase B is: licorice extract, giant knotweed extract, vitamin E, carbomer, phenylethyl resorcinol, glycyrrhiza glabra extract, allantoin, polyglutamic acid, ethylhexyl glycerol, coenzyme A, phenoxyethanol, arginine and mint extract.
On the other hand, the embodiment of the application provides a preparation method of the moisturizing, antioxidant and freckle-removing cream, which comprises the following steps:
the method comprises the following steps: heating Phase A to 45-75 ℃ through water bath, and stirring until the mixture is clear and transparent;
step two: adding Phase B, stirring until the mixture is transparent, and stirring until the mixture is transparent at the temperature of 50-80 ℃;
step three: cooling to 30-45 ℃, and continuing stirring;
step four: introducing the mixed solution in the third step into a filter screen for filtering;
step five: checking the pH value of the mixed liquor in the fourth step and adjusting the pH value to be 4.5-6.0.
In some embodiments of the present invention, the optimal temperature in the second step is 65 ℃.
In some embodiments of the present invention, the filtered crystals in step four above can be re-added to step two for mixing.
In some embodiments of the present invention, the optimal pH value in the fifth step is 5.0.
Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:
the lipoid and skin care product composition has good whitening and freckle removing effects, is beneficial to increasing the skin elasticity and the water content of the horny layer, has a simple preparation process, and is suitable for industrial large-scale production.
The freckle-removing cream component can avoid the oxidative decomposition or the illumination decomposition of the whitening freckle-removing component, and also solves the problem that the traditional monolayer phospholipid bilayer wrappage is easy to crack and release in advance in the permeation process, so that the whitening freckle-removing component can penetrate into a basal layer, and the whitening freckle-removing effect is obviously improved.
The freckle-removing cream has amphipathy, and can be applied to most cosmetics.
The freckle-removing cream has the components of compounded whitening and freckle-removing components, has good complementary and synergistic effects among the whitening and freckle-removing components, can simultaneously remove melanin from three aspects of inhibiting melanin formation, interfering melanin transfer and accelerating melanin degradation, and has more excellent whitening and freckle-removing effects.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a diagram showing specific parts by mass in example 5 of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
In this embodiment, the spot-removing cream comprises the following specific components in parts by mass: 72 parts of water, 5 parts of propylene glycol, 5 parts of 1, 2-butanediol, 5 parts of squalane, 5 parts of alpha-arbutin, 5 parts of glycerol, 5 parts of polyglycerol-10 oleate, 5 parts of isopropyl palmitate, 5 parts of cetearyl glucoside, 5 parts of glycerol stearate, 5 parts of cetearyl alcohol, 5 parts of a licorice extract, 5 parts of a polygonum cuspidatum extract, 1 part of tocopherol, 1 part of carbomer, 1 part of phenethylresorcinol, 1 part of a glycyrrhiza glabra extract, 0.5 part of allantoin, 0.5 part of polyglutamic acid, 0.5 part of ethylhexyl glycerol, 0.35 part of coenzyme A, 0.5 part of phenoxyethanol, 0.5 part of arginine, 0.2 part of a mint extract and 0.2 part of sodium hyaluronate.
Example 2
In this embodiment, the spot-removing cream comprises the following specific components in parts by mass: 70 parts of water, 3 parts of propylene glycol, 3 parts of 1, 2-butanediol, 3 parts of squalane, 3 parts of alpha-arbutin, 3 parts of glycerol, 3 parts of polyglycerol-10 oleate, 3 parts of isopropyl palmitate, 3 parts of cetearyl glucoside, 3 parts of glycerol stearate, 3 parts of cetearyl alcohol, 3 parts of licorice extract, 3 parts of giant knotweed extract, 1 part of tocopherol, 1 part of carbomer, 1 part of phenethyl resorcinol, 1 part of glycyrrhiza glabra extract, 0.3 part of allantoin, 0.3 part of polyglutamic acid, 0.3 part of ethylhexyl glycerol, 0.33 part of coenzyme A, 0.3 part of phenoxyethanol, 0.3 part of arginine, 0.1 part of mint extract and 0.1 part of sodium hyaluronate.
Example 3
In this embodiment, the spot-removing cream comprises the following specific components in parts by mass: 69 parts of water, 5 parts of propylene glycol, 5 parts of 1, 2-butanediol, 5 parts of squalane, 5 parts of alpha-arbutin, 5 parts of glycerol, 5 parts of polyglycerol-10 oleate, 5 parts of isopropyl palmitate, 5 parts of cetearyl glucoside, 5 parts of glycerol stearate, 5 parts of cetearyl alcohol, 5 parts of a licorice extract, 5 parts of a polygonum cuspidatum extract, 1 part of tocopherol, 1 part of carbomer, 1 part of phenethylresorcinol, 1 part of a glycyrrhiza glabra extract, 0.25 part of allantoin, 0.25 part of polyglutamic acid, 0.25 part of ethylhexyl glycerol, 0.25 part of coenzyme A, 0.25 part of phenoxyethanol, 0.25 part of arginine, 0.1 part of a mint extract and 0.1 part of sodium hyaluronate.
Example 4
In this embodiment, the spot-removing cream comprises the following specific components in parts by mass: 70 parts of water, 5 parts of propylene glycol, 3 parts of 1, 2-butanediol, 5 parts of squalane, 5 parts of alpha-arbutin, 5 parts of glycerol, 5 parts of polyglycerol-10 oleate, 2 parts of isopropyl palmitate, 5 parts of cetearyl glucoside, 5 parts of glycerol stearate, 5 parts of cetearyl alcohol, 5 parts of a licorice extract, 5 parts of a polygonum cuspidatum extract, 1 part of tocopherol, 1 part of carbomer, 1 part of phenethylresorcinol, 1 part of a glycyrrhiza glabra extract, 0.3 part of allantoin, 0.3 part of polyglutamic acid, 0.3 part of ethylhexyl glycerol, 0.3 part of coenzyme A, 0.3 part of phenoxyethanol, 0.3 part of arginine, 0.1 part of a mint extract and 0.1 part of sodium hyaluronate.
Example 5
In this embodiment, the specific components of the freckle removing cream include, by mass, 68 parts of water, 3 parts of propylene glycol, 3 parts of 1, 2-butylene glycol, 3 parts of squalane, 3 parts of α -arbutin, 2 parts of glycerol, 2 parts of polyglycerol-10 oleate, 2 parts of isopropyl palmitate, 2 parts of cetearyl glucoside, 2 parts of glycerol stearate, 2 parts of cetearyl alcohol, 2 parts of a licorice extract, 2 parts of a polygonum cuspidatum extract, 0.5 part of tocopherol, 0.5 part of carbomer, 0.5 part of phenethyl resorcinol, 0.5 part of glycyrrhiza glabra extract, 0.2 part of allantoin, 0.2 part of polyglutamic acid, 0.2 part of ethylhexyl glycerol, 0.2 part of coenzyme a, 0.2 part of phenoxyethanol, 0.2 part of arginine, 0.05 part of a mint extract, and 0.5 part of sodium hyaluronate.
In some embodiments of the present invention, the speckle removing cream is divided into Phase a and Phase B.
In some embodiments of the present invention, Phase a is: water, propylene glycol, 1, 2-butylene glycol, squalane, alpha-arbutin, glycerol, polyglycerol-10 oleate, isopropyl palmitate, cetearyl glucoside, glyceryl stearate and cetearyl alcohol.
In some embodiments of the present invention, Phase B is: licorice extract, giant knotweed extract, vitamin E, carbomer, phenylethyl resorcinol, glycyrrhiza glabra extract, allantoin, polyglutamic acid, ethylhexyl glycerol, coenzyme A, phenoxyethanol, arginine and mint extract.
In this embodiment, the embodiment provides a preparation method of a moisturizing, anti-oxidation and freckle-removing cream, which includes the following steps:
the method comprises the following steps: heating Phase A to 45-75 ℃ through water bath, and stirring until the mixture is clear and transparent;
step two: adding Phase B, stirring until the mixture is transparent, and stirring until the mixture is transparent at the temperature of 50-80 ℃;
step three: cooling to 30-45 ℃, and continuing stirring;
step four: introducing the mixed solution in the third step into a filter screen for filtering;
step five: checking the pH value of the mixed liquor in the fourth step and adjusting the pH value to be 4.5-6.0.
Example 6
In this embodiment, the embodiment provides a preparation method of a moisturizing, anti-oxidation and freckle-removing cream, which includes the following steps:
the method comprises the following steps: heating Phase A to 55 ℃ through a water bath, and stirring until the mixture is clear and transparent;
step two: adding Phase B, stirring until the mixture is transparent, and stirring until the mixture is transparent at the temperature of 65 ℃;
step three: cooling to 35 ℃, and continuing stirring;
step four: introducing the mixed solution in the third step into a filter screen for filtering;
step five: checking the pH value of the mixed liquor in the fourth step and adjusting the pH value to be 6.0.
Example 7
In this embodiment, the embodiment provides a preparation method of a moisturizing, anti-oxidation and freckle-removing cream, which includes the following steps:
the method comprises the following steps: heating Phase A to 55 ℃ through a water bath, and stirring until the mixture is clear and transparent;
step two: adding Phase B, stirring until the mixture is transparent, and stirring until the mixture is transparent at the temperature of 65 ℃;
step three: cooling to 45 ℃, and continuing stirring;
step four: introducing the mixed solution in the third step into a filter screen for filtering;
step five: checking the pH value of the mixed liquor in the fourth step and adjusting the pH value to be 4.5.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (10)

1. The moisturizing antioxidant freckle-removing cream is characterized by comprising the following components: water, propylene glycol, 1, 2-butylene glycol, squalane, alpha-arbutin, glycerol, polyglycerol-10 oleate, isopropyl palmitate, cetearyl glucoside, glyceryl stearate, cetearyl alcohol, licorice extract, polygonum cuspidatum extract, vitamin E, carbomer, phenylethyl resorcinol, glycyrrhiza glabra extract, allantoin, polyglutamic acid, ethylhexyl glycerol, coenzyme a, phenoxyethanol, arginine, and mint extract.
2. The moisturizing, antioxidant and freckle-removing cream according to claim 1, characterized in that the freckle-removing cream comprises the following specific components in percentage by mass: 68-72 parts of water, 3-5 parts of propylene glycol, 3-5 parts of 1, 2-butanediol, 3-5 parts of squalane, 3-5 parts of alpha-arbutin, 2-5 parts of glycerol, 2-5 parts of polyglycerol-10 oleate, 2-5 parts of isopropyl palmitate, 2-5 parts of cetearyl glucoside, 2-5 parts of glycerol stearate, 2-5 parts of cetearyl alcohol, 2-5 parts of licorice extract, 2-5 parts of polygonum cuspidatum extract, 0.5-1 part of tocopherol, 0.5-1 part of carbomer, 0.5-1 part of phenethyl resorcinol, 0.5-1 part of glycyrrhiza glabra extract, 0.2-0.5 part of allantoin, 0.2-0.5 part of polyglutamic acid, 0.2-0.5 part of ethylhexyl glycerol, 0.2-0.35 part of coenzyme A, 0.2-0.5 part of phenoxyethanol, 0.5 part of beta-methyl pyrrolidone, and the like, Arginine 0.2-0.5 parts and mint extract 0.05-0.2 parts.
3. The moisturizing, antioxidant and freckle-removing cream according to claim 2, wherein the freckle-removing cream comprises, by mass, 68 parts of water, 3 parts of propylene glycol, 3 parts of 1, 2-butanediol, 3 parts of squalane, 3 parts of alpha-arbutin, 2 parts of glycerol, 2 parts of polyglycerol-10 oleate, 2 parts of isopropyl palmitate, 2 parts of cetearyl glucoside, 2 parts of glycerol stearate, 2 parts of cetearyl alcohol, 2 parts of licorice extract, 2 parts of polygonum cuspidatum extract, 0.5 part of tocopherol, 0.5 part of carbomer, 0.5 part of phenethyl resorcinol, 0.5 part of glycyrrhiza glabra extract, 0.2 part of allantoin, 0.2 part of polyglutamic acid, 0.2 part of ethylhexyl glycerol, 0.2 part of coenzyme A, 0.2 part of phenoxyethanol, 0.2 part of arginine and 0.05 part of mint extract.
4. The moisturizing, antioxidant and freckle-removing cream according to claim 1, characterized in that: the components of the freckle removing cream are divided into Phase A and Phase B.
5. The moisturizing, antioxidant and freckle-removing cream according to claim 4, characterized in that: the Phase A is as follows: water, propylene glycol, 1, 2-butylene glycol, squalane, alpha-arbutin, glycerol, polyglycerol-10 oleate, isopropyl palmitate, cetearyl glucoside, glyceryl stearate and cetearyl alcohol.
6. The moisturizing, antioxidant and freckle-removing cream according to claim 4, characterized in that: the Phase B is as follows: licorice extract, giant knotweed extract, vitamin E, carbomer, phenylethyl resorcinol, glycyrrhiza glabra extract, allantoin, polyglutamic acid, ethylhexyl glycerol, coenzyme A, phenoxyethanol, arginine and mint extract.
7. The preparation method of the moisturizing, antioxidant and freckle-removing cream is characterized by comprising the following steps:
the method comprises the following steps: heating Phase A to 45-75 ℃ through water bath, and stirring until the mixture is clear and transparent;
step two: adding Phase B, stirring until the mixture is transparent, and stirring until the mixture is transparent at the temperature of 50-80 ℃;
step three: cooling to 30-45 ℃, and continuing stirring;
step four: introducing the mixed solution in the third step into a filter screen for filtering;
step five: checking the pH value of the mixed liquor in the fourth step and adjusting the pH value to be 4.5-6.0.
8. The preparation method of the moisturizing, antioxidant and freckle-removing cream according to claim 7, characterized by comprising the following steps: the optimal temperature in the second step is 65 ℃.
9. The preparation method of the moisturizing, antioxidant and freckle-removing cream according to claim 7, characterized by comprising the following steps: the filtered crystals in step four can be re-added to step two for mixing.
10. The preparation method of the moisturizing, antioxidant and freckle-removing cream according to claim 7, characterized by comprising the following steps: the optimal pH value in the step five is 5.0.
CN202111534876.0A 2021-12-15 2021-12-15 Moisturizing antioxidant freckle-removing cream and preparation method thereof Pending CN114129457A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115154360A (en) * 2022-05-31 2022-10-11 陕西慧康生物科技有限责任公司 Composition with whitening, freckle removing and moisturizing effects and application thereof
CN115282081A (en) * 2022-07-05 2022-11-04 浙江东印化妆品有限公司 Efficient whitening spot-fading and mark-repairing composition and application thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115154360A (en) * 2022-05-31 2022-10-11 陕西慧康生物科技有限责任公司 Composition with whitening, freckle removing and moisturizing effects and application thereof
CN115154360B (en) * 2022-05-31 2023-10-24 陕西慧康生物科技有限责任公司 Composition with whitening, freckle removing and moisturizing effects and application thereof
CN115282081A (en) * 2022-07-05 2022-11-04 浙江东印化妆品有限公司 Efficient whitening spot-fading and mark-repairing composition and application thereof

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