CN114126526A - 治疗性激光系统和方法 - Google Patents

治疗性激光系统和方法 Download PDF

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Publication number
CN114126526A
CN114126526A CN202080035415.6A CN202080035415A CN114126526A CN 114126526 A CN114126526 A CN 114126526A CN 202080035415 A CN202080035415 A CN 202080035415A CN 114126526 A CN114126526 A CN 114126526A
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CN
China
Prior art keywords
channel
target tissue
laser beam
nail
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080035415.6A
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English (en)
Chinese (zh)
Inventor
R·R·安德森
J·巴瓦尔卡
D·曼施泰因
J·廷
V·佐
L·加里拜安
李克雄
O·翁武迪韦
W·A·法里内利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American General Hospital
American Brewsom Innovation Co ltd
Original Assignee
American General Hospital
American Brewsom Innovation Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American General Hospital, American Brewsom Innovation Co ltd filed Critical American General Hospital
Publication of CN114126526A publication Critical patent/CN114126526A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/54—Chiropodists' instruments, e.g. pedicure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/203—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0068—Confocal scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
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    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/449—Nail evaluation, e.g. for nail disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A—HUMAN NECESSITIES
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
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    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61B2018/00642—Sensing and controlling the application of energy with feedback, i.e. closed loop control
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    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00702—Power or energy
    • A61B2018/00708—Power or energy switching the power on or off
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00738—Depth, e.g. depth of ablation
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    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00779—Power or energy
    • A61B2018/00785—Reflected power
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00904—Automatic detection of target tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B2018/2035—Beam shaping or redirecting; Optical components therefor
    • A61B2018/20351—Scanning mechanisms
    • A61B2018/20355—Special scanning path or conditions, e.g. spiral, raster or providing spot overlap
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B2018/2035—Beam shaping or redirecting; Optical components therefor
    • A61B2018/20351—Scanning mechanisms
    • A61B2018/20359—Scanning mechanisms by movable mirrors, e.g. galvanometric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electromagnetism (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
  • Laser Surgery Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN202080035415.6A 2019-03-15 2020-03-12 治疗性激光系统和方法 Pending CN114126526A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962818987P 2019-03-15 2019-03-15
US62/818,987 2019-03-15
PCT/US2020/022255 WO2020190610A1 (en) 2019-03-15 2020-03-12 Therapeutic laser system and method

Publications (1)

Publication Number Publication Date
CN114126526A true CN114126526A (zh) 2022-03-01

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Application Number Title Priority Date Filing Date
CN202080035415.6A Pending CN114126526A (zh) 2019-03-15 2020-03-12 治疗性激光系统和方法

Country Status (6)

Country Link
US (1) US11224378B2 (cg-RX-API-DMAC7.html)
EP (1) EP3937815A4 (cg-RX-API-DMAC7.html)
JP (2) JP2022525418A (cg-RX-API-DMAC7.html)
CN (1) CN114126526A (cg-RX-API-DMAC7.html)
TW (1) TW202042863A (cg-RX-API-DMAC7.html)
WO (1) WO2020190610A1 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

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US11515019B2 (en) * 2017-06-21 2022-11-29 H3Alth Technologies Inc. System and method for manufacturing custom nails
EP3937816B1 (en) * 2019-03-15 2025-05-21 The General Hospital Corporation Systems for laser-assisted topical treatment of nail fungal infections
WO2023193103A1 (en) * 2022-04-05 2023-10-12 Toefx Inc. Combined photodisinfection and visualization device

Citations (6)

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US20070161877A1 (en) * 2005-11-30 2007-07-12 Keio University Noninvasive measuring device for substance in blood via nail and a nail evaporation device
US20080208104A1 (en) * 2005-04-18 2008-08-28 Pantec Biosolutions Ag Laser Microporator
US20090069741A1 (en) * 2004-04-09 2009-03-12 Palomar Medical Technologies, Inc. Methods And Devices For Fractional Ablation Of Tissue For Substance Delivery
JP2014501124A (ja) * 2011-01-17 2014-01-20 アクティヴパック， インコーポレイテッド 無菌カートリッジおよびディスペンサ装置
US20150119825A1 (en) * 2012-04-20 2015-04-30 Galderma Research & Development Optimizing ungual treatment by quantitative autoradiography
US20150157877A1 (en) * 2006-04-12 2015-06-11 Searete Llc Autofluorescent imaging and target ablation

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US5897321A (en) * 1995-07-24 1999-04-27 International Business Machines Corporation Dental procedures and apparatus using ultraviolet radiation
US6050990A (en) * 1996-12-05 2000-04-18 Thermolase Corporation Methods and devices for inhibiting hair growth and related skin treatments
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GB0019283D0 (en) * 2000-08-04 2000-09-27 Novartis Ag Organic compounds
GB0203276D0 (en) * 2002-02-12 2002-03-27 Novartis Ag Organic compounds
US20110015549A1 (en) * 2005-01-13 2011-01-20 Shimon Eckhouse Method and apparatus for treating a diseased nail
WO2008089344A2 (en) * 2007-01-19 2008-07-24 Joseph Neev Devices and methods for generation of subsurface micro-disruptions for biomedical applications
WO2008152639A2 (en) 2007-06-12 2008-12-18 Bypass, Inc. Pressure pulse actuating device for delivery systems
US9572880B2 (en) * 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
DE102011052002B4 (de) 2011-07-20 2013-04-11 Telesto GmbH Lasertherapiesystem mit UVA- und IR-Laser-Licht zur gerichteten Erzeugung einer dermalen Kollagen-Matrix
US8888829B2 (en) * 2012-02-14 2014-11-18 Anthony Robert Ward Hand held system for antifungal treatment
US9504849B2 (en) 2013-03-14 2016-11-29 Plumeria Holdings, Llc Destruction of target cells utilizing harmonic resonance cavitation
JP6318239B2 (ja) * 2014-04-24 2018-04-25 株式会社ヤクルト本社 真菌核酸の抽出方法
WO2020190376A1 (en) 2019-03-15 2020-09-24 The General Hospital Corporation Systems and methods for laser-assisted topical treatment of nail fungal infections
EP3937816B1 (en) 2019-03-15 2025-05-21 The General Hospital Corporation Systems for laser-assisted topical treatment of nail fungal infections

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US20090069741A1 (en) * 2004-04-09 2009-03-12 Palomar Medical Technologies, Inc. Methods And Devices For Fractional Ablation Of Tissue For Substance Delivery
US20080208104A1 (en) * 2005-04-18 2008-08-28 Pantec Biosolutions Ag Laser Microporator
US20070161877A1 (en) * 2005-11-30 2007-07-12 Keio University Noninvasive measuring device for substance in blood via nail and a nail evaporation device
US20150157877A1 (en) * 2006-04-12 2015-06-11 Searete Llc Autofluorescent imaging and target ablation
JP2014501124A (ja) * 2011-01-17 2014-01-20 アクティヴパック， インコーポレイテッド 無菌カートリッジおよびディスペンサ装置
US20150119825A1 (en) * 2012-04-20 2015-04-30 Galderma Research & Development Optimizing ungual treatment by quantitative autoradiography

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Publication number Publication date
EP3937815A4 (en) 2022-11-16
JP2022525418A (ja) 2022-05-13
US20200323483A1 (en) 2020-10-15
WO2020190610A1 (en) 2020-09-24
EP3937815A1 (en) 2022-01-19
JP2025013967A (ja) 2025-01-28
US11224378B2 (en) 2022-01-18
TW202042863A (zh) 2020-12-01

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