CN114082734A - Cleaning system - Google Patents

Cleaning system Download PDF

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Publication number
CN114082734A
CN114082734A CN202111063819.9A CN202111063819A CN114082734A CN 114082734 A CN114082734 A CN 114082734A CN 202111063819 A CN202111063819 A CN 202111063819A CN 114082734 A CN114082734 A CN 114082734A
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CN
China
Prior art keywords
blending
lifting
motor
turntable
cleaning
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Pending
Application number
CN202111063819.9A
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Chinese (zh)
Inventor
李东琦
刘太文
王浩民
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Humanzhi Technology Co ltd
Nanjing Chenguang Medical Technology Co ltd
Original Assignee
Beijing Humanzhi Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Beijing Humanzhi Technology Co ltd filed Critical Beijing Humanzhi Technology Co ltd
Priority to CN202111063819.9A priority Critical patent/CN114082734A/en
Publication of CN114082734A publication Critical patent/CN114082734A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/20Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/22Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by soaking alone
    • B08B9/24Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by soaking alone and having conveyors
    • B08B9/26Rotating conveyors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/20Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/42Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus being characterised by means for conveying or carrying containers therethrough
    • B08B9/423Holders for bottles, cell construction

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention provides a cleaning system which comprises a bearing mechanism, wherein a lifting mechanism, a turntable mechanism and a blending mechanism are arranged on the bearing mechanism; the turntable mechanism is rotatably arranged on the bearing mechanism and is provided with a reagent tube; the blending mechanism is fixedly arranged on the bearing mechanism and is provided with a power shaft which is abutted with all or part of the reagent tubes and enables the reagent tubes to rotate; the lifting mechanism is provided with a cleaning piece, and the cleaning piece is driven by the lifting mechanism to move close to or away from the reagent tube. This application makes washing and mixing all can accomplish through a set of equipment, the occupation space that has significantly reduced to along with the rotation of reagent pipe, can also carry out a lot of cleaning work to it, make the washing more high-efficient.

Description

Cleaning system
Technical Field
The invention relates to the field of flow type fluorescence immunoassay equipment, in particular to a cleaning system.
Background
In the flow type fluorescence immunoassay, a mixed solution of magnetic beads and a sample reagent is needed in the testing process, the mixed solution of the magnetic beads and the sample reagent is determined by the physical characteristics of the mixed solution, and once the mixed solution is kept still, precipitates are easy to generate, and the mixed solution of the reagent can be cleaned for many times to achieve the purpose of final detection; if the magnetic bead precipitation phenomenon occurs or the washing is not efficient, the experimental result is affected. At present, the magnetic bead precipitation and cleaning processes are mostly carried out independently by two sets of equipment, stirring and uniformly mixing are carried out on a magnetic bead reagent by adopting a stirring mechanism mostly, and then the reagent mixed liquid is cleaned by utilizing other equipment.
In view of the above, the present invention is particularly proposed.
Disclosure of Invention
The invention provides a cleaning system, which aims to solve the technical problems that multiple cleaning processes are required, the cleaning processes are independent, the cost is high, the time consumption is long, and the like.
A cleaning system, comprising: the loading mechanism is provided with a lifting mechanism, a turntable mechanism and a blending mechanism;
the turntable mechanism is rotatably arranged on the bearing mechanism and is provided with a reagent tube; the blending mechanism is fixedly arranged on the bearing mechanism and is provided with a power shaft which is abutted with all or part of the reagent tubes and enables the reagent tubes to rotate;
the lifting mechanism is provided with a cleaning piece, and the cleaning piece is driven by the lifting mechanism to move close to or away from the reagent tube.
By adopting the technical scheme, the cleaning system comprises cleaning and mixing, during mixing, the reagent tubes on the turntable mechanism are rotated along the central position through the rotating turntable mechanism, so that the positions are changed, then the cleaning piece on the lifting mechanism is close to the reagent tubes to clean each reagent tube, and the reagent tubes are enabled to rotate through the mixing mechanism, so that the reagent added in the reagent tubes is shaken, and the purpose of mixing is achieved;
cleaning and mixing are completed according to the method, so that cleaning and mixing can be completed through one set of equipment, the occupied space is greatly reduced, and cleaning can be performed for many times along with rotation of the reagent tube, so that cleaning is more efficient.
Preferably, the bearing mechanism comprises a bearing plate and a mounting ring, the turntable mechanism is rotatably connected to the bearing plate and is positioned in the mounting ring, and the blending mechanism is fixed on the bearing plate and is positioned in the turntable mechanism;
a plurality of support rods are fixed on the bearing plate, and the mounting ring is fixed with the support rods so as to suspend in the air;
the lifting mechanism comprises a lifting mounting frame and a lifting assembly, the lifting mounting frame is fixedly connected with the bearing plate, the lifting assembly is connected with a needle mounting frame, the cleaning piece is a cleaning needle, and the cleaning needle is fixed with the needle mounting frame.
The mounting ring is abutted with the reagent tube, so that the reagent tube can be abutted with the inner wall of the mounting ring when the turntable mechanism rotates, and the reagent tube is prevented from falling; and the cleaning needle on the needle mounting rack is driven to move up and down by the lifting of the lifting component on the lifting mounting rack, and new cleaning liquid is added again to perform new cleaning work after the cleaning needle extracts waste liquid.
Preferably, the turntable mechanism at least comprises a turntable and a rotating motor, a clamping groove is formed in the turntable, a placing space for placing the reagent tube is formed between the clamping groove and the mounting ring, and the turntable is driven by the rotating motor to drive the reagent tube to periodically rotate along the center;
and/or;
the blending mechanism at least comprises a blending driving component and a blending motor, the blending driving component is abutted to the reagent tube, and the blending motor drives the blending driving component to rotate so that the reagent tube rotates mutually to blend.
In this way, the rotating disc or the blending driving part is driven to rotate by rotating the motor or the blending motor, so that the reagent tube periodically rotates or autorotates along the center.
Preferably, be provided with the application of sample mounting bracket on the needle mounting bracket, be equipped with cantilever motor on the application of sample mounting bracket, be provided with the application of sample cantilever on cantilever motor's the main shaft, be fixed with the application of sample needle on the application of sample cantilever.
Can drive the application of sample cantilever through cantilever motor and rotate for the application of sample needle rotates the top of reagent pipe, and the needle mount frame accomplishes the application of sample work to in the reagent pipe through the application of sample needle when moving downwards.
Preferably, a blending follow-up mechanism opposite to the blending driving component is arranged on the mounting ring,
the mixing follow-up mechanism comprises an installation block, a follower positioned above the installation ring is fixed on the installation block, and a follow-up roller facing the mixing active component is rotatably connected onto the follower.
When mixing initiative subassembly made the rotation take place for the reagent pipe like this, rather than relative follow-up gyro wheel and reagent pipe butt, follow-up gyro wheel also can rotate thereupon, can make the reagent pipe rotation on the one hand reduce and the mount ring between the frictional force like this, on the other hand can balance the centrifugal force that the rotation produced, can be so that the mixing effect is better.
Preferably, the mounting ring is provided with magnets arranged circumferentially, the lower part of the mounting ring is provided with a flow guide edge, and the mounting ring is further provided with an inlet pipe position detection photoelectric sensor and an outlet pipe position detection photoelectric sensor respectively.
Due to the action of the magnet, the magnetic beads in the reagent tube can be adsorbed on one side of the inner part of the reagent tube, and the structure mode can enable the uniformly mixed magnetic beads to quickly form a group to package large particles, so that the adsorption force of the magnetic beads can be increased when the magnetic beads are cleaned in an adsorption process for 3 times, the magnetic beads are close to the inner side of the wall of the reagent tube to the maximum extent, and the loss rate of the magnetic beads is reduced; when a fault occurs, liquid can drip downwards along the diversion edge, the whole cleaning system cannot be polluted, a water outlet is formed in the lower bearing plate, and waste liquid can flow into the waste liquid barrel through the water outlet hole.
The pipe inlet position detection photoelectric sensor can detect whether a pipe is fed or not, if the pipe inlet position detection photoelectric sensor is triggered, the turntable drives the rotating cup position through the turntable driving motor, and the pipe outlet position detection photoelectric sensor can detect a reagent pipe which rotates to the position, and the reagent pipe is grabbed and moved out to a next step for testing after being detected by the subsequent hand grab.
Preferably, the turntable is positioned between the bearing plate and the mounting ring, the rotating motor is provided with first synchronous belt wheels, a first synchronous belt is connected between the two first synchronous belt wheels, and the rotating motor drives the turntable to rotate through the first synchronous belt.
Can drive first synchronous belt wheel through rotating the motor and rotate the drive work to the carousel like this, and rotate the motor and be located one side, reduce area occupied.
Preferably, the blending active component comprises a bearing mounting seat arranged on the surface of the bearing plate, the bearing mounting seat is rotatably connected with a power shaft, and a rubber ring is sleeved on the power shaft;
the bearing mounting base is provided with a plurality of, is equipped with second synchronous pulley on every power shaft and the mixing motor respectively, is connected with the second hold-in range between a plurality of second synchronous pulley, makes a plurality of power shafts establish ties, makes the mixing motor drive a plurality of mixing drive assembly simultaneously through the second hold-in range and rotates.
The reagent tube self-rotating device is characterized in that the reagent tube self-rotating device is contacted with the reagent tube through a rubber ring to enable the reagent tube to rotate, a plurality of bearing installation seats are arranged to enable a plurality of reagent tubes to rotate simultaneously, and a plurality of power shafts can be enabled to rotate simultaneously by connecting a second synchronous belt with a plurality of second synchronous belt wheels in series.
Preferably, the lifting assembly comprises a lifting screw rod and a lifting motor;
the lifting motor is fixed on the bearing plate, one end of the lifting screw rod is connected with the needle mounting frame, and the other end of the lifting screw rod is connected with the lifting motor;
the needle mounting frame is fixed with a sliding block connected with the sliding rail in a sliding mode.
Specifically, the lifting screw rod is rotated through the lifting motor, and the needle mounting rack can be moved up and down through the sliding of the sliding block on the sliding rail through the rotation of the lifting screw rod.
Preferably, a follower shaft is rotatably connected in one of the bearing mounting seats, the power shaft is meshed with the follower shaft through a gear, the second synchronous belt penetrates through the power shaft, and the rubber ring is sleeved on the follower shaft.
The power shaft drives the follow-up shaft to enable the mixing effect of the last cup to be better, and the mixing force is required to be faster after the substrate liquid is added, so that the reagent is fully mixed.
In conclusion, the reagent tubes are rotated along the central position by rotating the rotating motor to drive the rotating disc to rotate, so that the position is changed, the cleaning needle on the needle mounting frame is driven by the lifting motor to be close to the reagent tubes to clean each reagent tube, and the reagent tubes are driven by the blending motor to rotate by driving the power shaft abutted to the reagent tubes, so that the reagents added in the reagent tubes are shaken, and the blending purpose is achieved;
cleaning and mixing are completed according to the method, so that cleaning and mixing can be completed through one set of equipment, the occupied space is greatly reduced, and cleaning can be performed for many times along with rotation of the reagent tube, so that cleaning is more efficient.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a schematic structural view of a blending system provided by the present invention;
FIG. 2 is a schematic view of another aspect of the present invention;
FIG. 3 is a schematic structural view of another side of the mixing system of the present invention;
FIG. 4 is an enlarged view of A in FIG. 3;
fig. 5 is a schematic structural diagram of the mounting ring provided by the invention.
In the above figures, the list of parts represented by the various reference numerals is as follows:
1. a carrier plate; 2. a mounting ring; 3. a support bar; 4. a lifting mounting rack; 5. a needle mounting bracket; 6. cleaning the needle; 7. a turntable; 8. rotating the motor; 9. a mixing motor; 10. a sample adding mounting rack; 11. a cantilever motor; 12. a sample adding cantilever; 13. a sample adding needle; 14. mounting blocks; 15. a follower; 16. a follow-up roller; 17. a first timing pulley; 18. a first synchronization belt; 19. a bearing mount; 20. a power shaft; 21. a rubber ring; 22. a second timing pulley; 23. a second synchronous belt; 24. a lifting screw rod; 25. a lifting motor; 26. a slide rail; 27. a slider; 28. a follower shaft; 29. a magnet; 30. a flow guiding edge; 31. detecting a photoelectric sensor at the tube entering position; 32. and detecting a photoelectric sensor for the pipeline position.
Detailed Description
In order to make the above and other features and advantages of the present invention more apparent, the present invention is further described below with reference to the accompanying drawings. It is understood that the specific embodiments described herein are for purposes of illustration only and are not intended to be limiting.
In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
Referring to fig. 1-5, in one embodiment provided by the present invention, there is provided a washing system including: the bearing mechanism is provided with a lifting mechanism, a turntable 7 mechanism and a blending mechanism;
the turntable 7 mechanism is rotatably arranged on the bearing mechanism and is provided with a reagent tube; the blending mechanism is fixedly arranged on the bearing mechanism and is provided with a power shaft 20 which is abutted with all or part of the reagent tubes and enables the reagent tubes to rotate; the lifting mechanism is provided with a cleaning piece, and the cleaning piece is driven by the lifting mechanism to move close to or away from the reagent tube.
By adopting the technical scheme, the cleaning system comprises cleaning and mixing, when mixing, the rotating turntable 7 mechanism enables the reagent tubes on the turntable 7 mechanism to rotate along the central position, so that the positions are changed, the cleaning piece on the lifting mechanism is close to the reagent tubes to clean each reagent tube, and the mixing mechanism enables the reagent tubes to rotate, so that the reagent added in the reagent tubes is shaken, and the purpose of mixing is achieved;
cleaning and mixing are completed according to the method, so that cleaning and mixing can be completed through one set of equipment, the occupied space is greatly reduced, and cleaning can be performed for many times along with rotation of the reagent tube, so that cleaning is more efficient.
In addition to the above embodiments, other embodiments of the present application may be further added or defined by one or more of the following combinations based on the above specific embodiments.
The bearing mechanism comprises a bearing plate 1 and a mounting ring 2, the turntable 7 mechanism is rotationally connected to the bearing plate 1 and is positioned in the mounting ring 2, and the uniformly mixing mechanism is fixed on the bearing plate 1 and is positioned in the turntable 7 mechanism; a plurality of support rods 3 are fixed on the bearing plate 1, and the mounting ring 2 is fixed with the support rods 3 so that the mounting ring 2 is suspended in the air; elevating system includes lift mounting bracket 4 and lifting unit, lift mounting bracket 4 with 1 rigid coupling of loading board, last needle mounting bracket 5 that is connected with of lifting unit, it is washing needle 6 to wash the piece, wash needle 6 with needle mounting bracket 5 is fixed.
The mounting ring 2 is abutted with the reagent tube, so that the reagent tube can be abutted with the inner wall of the mounting ring 2 when the turntable 7 mechanism rotates, and the reagent tube is prevented from falling; and the cleaning needle 6 on the needle mounting rack 5 is driven to move up and down by the lifting of the lifting component on the lifting mounting rack 4, and new cleaning liquid is added again to perform new cleaning work after the cleaning needle 6 extracts waste liquid.
The turntable 7 mechanism at least comprises a turntable 7 and a rotating motor 8, a clamping groove is formed in the turntable 7, a placing space for placing the reagent tube is formed between the clamping groove and the mounting ring 2, and the turntable 7 is driven by the rotating motor 8 to drive the reagent tube to periodically rotate along the center;
and/or;
the blending mechanism at least comprises a blending driving component and a blending motor 9, the blending driving component is abutted to the reagent tube, and the blending motor 9 drives the blending driving component to rotate so that the reagent tube rotates mutually to blend.
In this way, the rotating motor 8 or the blending motor 9 is specifically rotated to drive the rotating disc 7 or the blending driving part to rotate, so that the reagent tube periodically rotates or autorotates along the center.
Be provided with application of sample mounting bracket 10 on the needle mounting bracket 5, be equipped with cantilever motor 11 on the application of sample mounting bracket 10, be provided with application of sample cantilever 12 on cantilever motor 11's the main shaft, be fixed with application of sample needle 13 on the application of sample cantilever 12.
Can drive application of sample cantilever 12 through cantilever motor 11 and rotate for application of sample needle 13 rotates the top of reagent pipe, and needle mounting bracket 5 accomplishes the application of sample work to in the reagent pipe through application of sample needle 13 when moving downwards.
Be provided with the mixing follower mechanism relative with mixing initiative component on the collar 2, mixing follower mechanism includes installation piece 14, be fixed with the follower 15 that is located collar 2 top on the installation piece 14, the last swivelling joint of follower 15 has the follow-up gyro wheel 16 towards mixing initiative component.
When mixing initiative subassembly made the rotation take place for the reagent pipe like this, with its relative follow-up gyro wheel 16 and reagent pipe butt, follow-up gyro wheel 16 also can rotate thereupon, can make the reagent pipe reduce when the rotation and the collar 2 between frictional force like this on the one hand, on the other hand can balance the centrifugal force that the rotation produced, can be so that the mixing effect is better.
The mounting ring 2 is provided with magnets 29 arranged in a circumferential manner, the lower portion of the mounting ring 2 is provided with a flow guide edge 30, and the mounting ring 2 is further provided with an inlet pipe position detection photoelectric sensor 31 and an outlet pipe position detection photoelectric sensor 32.
Due to the action of the magnet 29, the magnetic beads in the reagent tube can be adsorbed on one side of the inner part of the reagent tube, and the structure mode can enable the uniformly mixed magnetic beads to quickly form a group to contain large particles, so that the adsorption force of the magnetic beads can be increased when the magnetic beads are cleaned in the adsorption process for 3 times, the magnetic beads are close to the inner side of the wall of the reagent tube to the maximum extent, and the loss rate of the magnetic beads is reduced; when breaking down, liquid can be through the water conservancy diversion along 30 drippage downwards, can not pollute whole cleaning system, is equipped with the delivery port on the lower part loading board 1, and the waste liquid can flow into in the waste liquid bucket through the apopore.
The pipe inlet position detection photoelectricity can detect whether to enter a pipe, if the pipe inlet position detection photoelectricity is triggered, the turntable 7 drives the motor to rotate a cup position through the turntable 7, the pipe outlet position detection photoelectricity sensor 32 can detect a reagent pipe which rotates to the position, and the reagent pipe is grabbed and moved out to a next step for testing after being detected by a follow-up hand grab.
The turntable 7 is positioned between the bearing plate 1 and the mounting ring 2, the rotating motor 8 is respectively provided with a first synchronous belt 18 wheel 17, a first synchronous belt 18 is connected between the two first synchronous belt 18 wheels 17, and the rotating motor 8 drives the turntable 7 to rotate through the first synchronous belt 18.
Therefore, the driving work of the turntable 7 can be completed by driving the first synchronous belt 18 wheel 17 to rotate through the first synchronous belt 18 by rotating the motor 8, and the rotating motor 8 is positioned on one side, so that the occupied area is reduced.
The blending active component comprises a bearing mounting seat 19 arranged on the surface of the bearing plate, a power shaft 20 is rotatably connected onto the bearing mounting seat 19, and a rubber ring 21 is sleeved on the power shaft 20; bearing mount pad 19 is equipped with a plurality ofly, is equipped with second hold-in range 23 wheel 22 on every power shaft 20 and the mixing motor 9 respectively, is connected with second hold-in range 23 between a plurality of second hold-in range 23 wheels 22, makes a plurality of power shafts 20 establish ties, makes mixing motor 9 drive a plurality of mixing initiative subassembly rotations simultaneously through second hold-in range 23.
Specifically, the reagent tubes are contacted with the rubber rings 21 to rotate, and the plurality of bearing holders 19 are provided to simultaneously rotate the plurality of reagent tubes, and the plurality of power shafts 20 are simultaneously rotated by connecting a plurality of second timing belts 23 in series with a plurality of second timing belt 23 wheels 22 through one second timing belt 23.
The lifting assembly comprises a lifting screw rod 24 and a lifting motor 25; the lifting motor 25 is fixed on the bearing plate 1, one end of the lifting screw rod 24 is connected with the needle mounting frame 5, and the other end of the lifting screw rod 24 is connected with the lifting motor 25; a slide rail 26 is fixed on the lifting mounting frame 4, and a slide block 27 which is connected with the slide rail 26 in a sliding manner is fixed on the needle mounting frame 5.
Specifically, the lifting screw rod 24 is rotated by the lifting motor 25, and the needle mounting frame 5 can be moved up and down by the sliding of the slider 27 on the slide rail 26 by the rotation of the lifting screw rod 24.
One of the bearing mounting seats 19 is internally and respectively and rotatably connected with a power shaft 20 and a follower shaft 28, the power shaft 20 is meshed with the follower shaft 28 through a gear, a second synchronous belt 23 penetrates through the power shaft 20, and a rubber ring 21 is sleeved on the follower shaft 28.
The power shaft 20 drives the follow-up shaft 28 to enable the blending effect of the last cup to be better, and after the substrate liquid is added, the blending force needs to be faster, so that the reagents can be fully blended.
In conclusion, the reagent tubes are rotated along the central position by driving the rotation of the rotary table 7 through the rotating motor 8, so that the positions are changed, the cleaning needles 6 on the needle mounting rack 5 are driven by the lifting motor 25 to be close to the reagent tubes to clean each reagent tube, and the power shaft 20 abutted against the reagent tubes is driven by the blending motor 9 to rotate so as to rotate the reagent tubes, so that the reagents added in the reagent tubes are shaken, and the purpose of blending is achieved;
cleaning and mixing are completed according to the method, so that cleaning and mixing can be completed through one set of equipment, the occupied space is greatly reduced, and cleaning can be performed for many times along with rotation of the reagent tube, so that cleaning is more efficient.
Referring to fig. 1-5, in some embodiments provided by the present invention, the cleaning system includes a carrying mechanism, on which a lifting mechanism, a rotating disc 7 mechanism and a blending mechanism are disposed; wherein carousel 7 mechanism rotates and sets up on bearing the weight of the mechanism, and has laid reagent pipe, and mixing mechanism is fixed to be set up on bearing the weight of the mechanism, is provided with the washing piece on the elevating system, and washs the action that the piece realized being close to or keeping away from under elevating system's drive reagent pipe.
The mounting ring 2 is provided with circumferentially arranged magnets 29, a guide edge 30 at the lower part thereof, and an inlet position detection photoelectric sensor 31 and an outlet position detection photoelectric sensor 32.
The bearing mechanism comprises a bearing plate 1 and a mounting ring 2, and the mounting ring 2 is suspended in the air through a support rod 3 arranged on the bearing plate 1; elevating system includes lift mounting bracket 4 and lifting unit, lift mounting bracket 4 and the 1 rigid coupling of loading board, the last needle mounting bracket 5 that is connected with of lifting unit, and it is fixed with needle mounting bracket 5 to wash the needle.
The lifting assembly comprises a lifting screw rod 24 and a lifting motor 25, the lifting motor 25 is fixed on the bearing plate 1, one end of the lifting screw rod 24 is connected with the needle mounting frame 5, and the other end of the lifting screw rod 24 is connected with the lifting motor 25; a slide rail 26 is fixed on the lifting mounting frame 4, and a slide block 27 which is connected with the slide rail 26 in a sliding way is fixed on the needle mounting frame 5.
The turntable 7 mechanism comprises a turntable 7 and a rotating motor 8, a clamping groove is formed in the turntable 7, a placing space for placing the reagent tube is formed between the clamping groove and the mounting ring 2, a first synchronous belt 18 wheel 17 is arranged on the turntable 7 and positioned between the bearing plate 1 and the mounting ring 2 and on the rotating motor 8 respectively, a first synchronous belt 18 is connected between the two first synchronous belt 18 wheels 17, and the rotating motor 8 drives the turntable 7 to rotate through the first synchronous belt 18.
The blending mechanism at least comprises a blending active component and a blending motor 9, the blending active component is abutted against the reagent tube, the blending active component comprises a plurality of bearing installation seats 19 arranged on the surface of a bearing plate, the bearing installation seats 19 are rotatably connected with power shafts 20, and the power shafts 20 are sleeved with rubber rings 21; a second synchronous belt 23 wheel 22 is respectively arranged on each power shaft 20 and the blending motor 9, a second synchronous belt 23 is connected between the plurality of second synchronous belt 23 wheels 22, so that the plurality of power shafts 20 are connected in series, and the blending motor 9 simultaneously drives the plurality of blending driving components to rotate through the second synchronous belt 23;
one of the bearing mounting seats 19 is internally and respectively and rotatably connected with a power shaft 20 and a follower shaft 28, the power shaft 20 is meshed with the follower shaft 28 through a gear, a second synchronous belt 23 penetrates through the power shaft 20, and a rubber ring 21 is sleeved on the follower shaft 28.
The mounting ring 2 is provided with a mixing follow-up mechanism which is opposite to the mixing driving component, the mixing follow-up mechanism comprises a mounting block 14, a follower 15 which is positioned above the mounting ring 2 is fixed on the mounting block 14, and a follow-up roller 16 which faces the mixing driving component is rotatably connected to the follower 15.
Be provided with application of sample mounting bracket 10 on the needle mounting bracket 5, be equipped with cantilever motor 11 on the application of sample mounting bracket 10, be provided with application of sample cantilever 12 on cantilever motor 11's the main shaft, be fixed with application of sample needle 13 on the application of sample cantilever 12.
The working process of the invention is as follows:
firstly, whether a tube is inserted is detected by a tube insertion position detection photoelectric sensor 31, if tube insertion position detection photoelectric is triggered, a rotary disc 7 is driven by a rotary disc 7 motor to rotate by a cup position, when a reagent tube moves to a blending mechanism, a blending motor 9 drives a power shaft 20 to rotate, the reagent tube can be driven to rotate under the action of friction force of a rubber ring 21, a needle mounting frame 5 can move downwards under the action of an elevating screw rod 24 while the reagent tube rotates, liquid in the reagent tube is extracted by a cleaning needle 6, new cleaning liquid is added again after waste liquid is extracted, when the reagent tube is arranged in 24 hole positions on the rotary disc 7, the rotary disc 7 is cleaned once when rotating by one hole position, and 1 reagent tube can be cleaned for multiple times when rotating for one circle in the whole cleaning station; when the reagent tube rotates to other positions of the cleaning position, the magnetic beads in the reagent tube can be adsorbed on one side of the inner part of the reagent tube due to the action of the magnet 29, the uniformly mixed magnetic beads can quickly form large particles, the adsorption force of the magnetic beads can be increased during cleaning through 3 times of adsorption processes, the magnetic beads are close to the inner side of the wall of the reagent tube to the maximum extent, and the loss rate of the magnetic beads is reduced; when the reagent tube rotates to the sample adding position, the sample adding needle 13 rotates to the sample adding position through the cantilever motor 11 to add samples, and finally the reagent tube rotates to the tube discharging position to detect the position of the photoelectric sensor 32 and is moved out by the hand grip to be tested in the next step.
Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art within the scope of the present invention.

Claims (10)

1. A cleaning system, comprising: the loading mechanism is provided with a lifting mechanism, a turntable mechanism and a blending mechanism;
the turntable mechanism is rotatably arranged on the bearing mechanism and is provided with a reagent tube; the blending mechanism is fixedly arranged on the bearing mechanism and is provided with a power shaft which is abutted with all or part of the reagent tubes and enables the reagent tubes to rotate;
the lifting mechanism is provided with a cleaning piece, and the cleaning piece is driven by the lifting mechanism to move close to or away from the reagent tube.
2. The cleaning system of claim 1, wherein the bearing mechanism comprises a bearing plate and a mounting ring, the turntable mechanism is rotatably connected to the bearing plate and located in the mounting ring, and the blending mechanism is fixed to the bearing plate and located in the turntable mechanism;
a plurality of support rods are fixed on the bearing plate, and the mounting ring is fixed with the support rods so as to suspend in the air;
the lifting mechanism comprises a lifting mounting frame and a lifting assembly, the lifting mounting frame is fixedly connected with the bearing plate, and the lifting assembly is connected with a needle mounting frame;
the cleaning piece is a cleaning needle, and the cleaning needle is fixed with the needle mounting frame.
3. The cleaning system of claim 2, wherein the turntable mechanism at least comprises a turntable and a rotating motor, the turntable is provided with a slot, a placing space for placing the reagent tube is formed between the slot and the mounting ring, and the turntable is driven by the rotating motor to drive the reagent tube to periodically rotate along the center;
and/or;
the blending mechanism at least comprises a blending driving component and a blending motor, the blending driving component is abutted to the reagent tube, and the blending motor drives the blending driving component to rotate so that the reagent tube rotates mutually to blend.
4. The cleaning system of claim 2, wherein the needle mounting bracket is provided with a sample application mounting bracket, the sample application mounting bracket is provided with a cantilever motor, a main shaft of the cantilever motor is provided with a sample application cantilever, and a sample application needle is fixed on the sample application cantilever.
5. The cleaning system of claim 3, wherein the mounting ring is provided with a blending follower opposite to the blending active component,
the mixing follow-up mechanism comprises an installation block, a follower positioned above the installation ring is fixed on the installation block, and a follow-up roller facing the mixing active component is rotatably connected onto the follower.
6. The cleaning system of claim 2, wherein the mounting ring is provided with circumferentially arranged magnets, the lower portion of the mounting ring is provided with a guide edge, and the mounting ring is further provided with an incoming position detection photoelectric sensor and an outgoing position detection photoelectric sensor, respectively.
7. The cleaning system of claim 3, wherein the turntable is provided with a first synchronous belt pulley between the bearing plate and the mounting ring and a first synchronous belt pulley between the first synchronous belt pulley and the rotating motor, and the rotating motor drives the turntable to rotate through the first synchronous belt.
8. The cleaning system of claim 3, wherein the blending active component comprises a bearing mounting seat arranged on the surface of the bearing plate, the bearing mounting seat is rotatably connected with a power shaft, and a rubber ring is sleeved on the power shaft;
the bearing mounting base is provided with a plurality of, is equipped with second synchronous pulley on every power shaft and the mixing motor respectively, is connected with the second hold-in range between a plurality of second synchronous pulley, makes a plurality of power shafts establish ties, makes the mixing motor drive a plurality of mixing drive assembly simultaneously through the second hold-in range and rotates.
9. The cleaning system of claim 2, wherein the lift assembly includes a lift screw and a lift motor;
the lifting motor is fixed on the bearing plate, one end of the lifting screw rod is connected with the needle mounting frame, and the other end of the lifting screw rod is connected with the lifting motor;
the needle mounting frame is fixed with a sliding block connected with the sliding rail in a sliding mode.
10. The cleaning system of claim 8, wherein a follower shaft is rotatably connected in one of the bearing mounts, the power shaft and the follower shaft are engaged through a gear, the second synchronous belt passes through the power shaft, and the rubber ring is sleeved on the follower shaft.
CN202111063819.9A 2021-09-10 2021-09-10 Cleaning system Pending CN114082734A (en)

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CN202111063819.9A CN114082734A (en) 2021-09-10 2021-09-10 Cleaning system

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CN202111063819.9A CN114082734A (en) 2021-09-10 2021-09-10 Cleaning system

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104237545A (en) * 2014-09-30 2014-12-24 博奥赛斯(天津)生物科技有限公司 Chemiluminescent immune assay blending device
CN104722526A (en) * 2015-03-20 2015-06-24 北京中航赛维生物科技有限公司 Magnetism separating device
CN108732163A (en) * 2018-07-24 2018-11-02 山东博科诊断科技有限公司 Full-automatic chemiluminescence immunoassay analysis meter
CN110883001A (en) * 2019-12-03 2020-03-17 北京乐普医疗科技有限责任公司 Magnetic bead cleaning device for analyzer
CN210982226U (en) * 2019-11-06 2020-07-10 湖南远璟生物技术有限公司 Magnetic bead separation and cleaning device with mixed structure
CN111521833A (en) * 2019-12-19 2020-08-11 威海威高生物科技有限公司 Chemiluminescence immunoassay reaction disc with multiple reaction modes and analyzer
US20210162473A1 (en) * 2019-11-29 2021-06-03 Shenzhen New Industries Biomedical Engineering Co., Ltd. Cleaning Module, Sample Analyzer with Cleaning Module and Cleaning method

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104237545A (en) * 2014-09-30 2014-12-24 博奥赛斯(天津)生物科技有限公司 Chemiluminescent immune assay blending device
CN104722526A (en) * 2015-03-20 2015-06-24 北京中航赛维生物科技有限公司 Magnetism separating device
CN108732163A (en) * 2018-07-24 2018-11-02 山东博科诊断科技有限公司 Full-automatic chemiluminescence immunoassay analysis meter
CN210982226U (en) * 2019-11-06 2020-07-10 湖南远璟生物技术有限公司 Magnetic bead separation and cleaning device with mixed structure
US20210162473A1 (en) * 2019-11-29 2021-06-03 Shenzhen New Industries Biomedical Engineering Co., Ltd. Cleaning Module, Sample Analyzer with Cleaning Module and Cleaning method
CN110883001A (en) * 2019-12-03 2020-03-17 北京乐普医疗科技有限责任公司 Magnetic bead cleaning device for analyzer
CN111521833A (en) * 2019-12-19 2020-08-11 威海威高生物科技有限公司 Chemiluminescence immunoassay reaction disc with multiple reaction modes and analyzer

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