CN114062205A

CN114062205A - Blood cell analyzer and cleaning method thereof

Info

Publication number: CN114062205A
Application number: CN202110852635.4A
Authority: CN
Inventors: 石汇林; 滕锦; 叶燚
Original assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Current assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date: 2020-07-31
Filing date: 2021-07-27
Publication date: 2022-02-18

Abstract

The invention provides a blood cell analyzer and a cleaning method thereof, the blood cell analyzer comprises: the mode setting module is used for setting the working mode of the blood cell analyzer; the sampling distribution module is used for collecting a blood sample and distributing the blood sample to the blood sedimentation detection module and/or the blood routine detection module; the erythrocyte sedimentation rate detection module is used for detecting the erythrocyte sedimentation rate of the blood sample; the blood routine detection module is used for performing blood routine detection on the blood sample; the liquid path support module is at least used for cleaning the sampling distribution module; the control device is at least used for controlling at least one of the blood sedimentation detection module and the blood routine detection module to operate according to a set working mode; the blood cell analyzer is also provided with different cleaning modes, and the control device is also used for controlling the liquid path support module to execute the corresponding cleaning mode according to the set working mode so as to clean the sampling distribution module. The scheme of the invention can improve the testing speed and save the using amount of the cleaning solution.

Description

Blood cell analyzer and cleaning method thereof

Technical Field

The invention relates to the technical field of medical equipment, in particular to a blood cell analyzer and a cleaning method thereof.

Background

At present in some five categorised blood cell analyses, in order to satisfy the demand of user's low sampling volume, can design the measurement system who realizes trace blood measurement, instrument appearance volume of inhaling is generally below 40 μ L, and the sampling system sampling back of this type of trace volume of inhaling, because the sampling needle has certain volume, the sample is generally stored inside the sampling needle, and the sampling system divides blood to each passageway again, and it is inside to wash the sampling needle after dividing the blood.

With the increasing clinical demand, more measurement modules are added in the five-classification blood cell analyzer to realize the measurement of more parameters in an all-in-one machine mode; for example, in an implementation scheme of a conventional integrated machine for blood sedimentation, a blood sedimentation measurement module is integrated on a sampling channel, and blood sedimentation measurement and conventional blood sedimentation measurement can be realized after one-time sampling; the sampling system samples a certain amount of blood samples, and after the blood separation of the conventional blood channel is finished, the rest samples are dragged to the blood sedimentation sensor for testing. As shown in figure 1, the conventional integrated machine structure for blood sedimentation has the advantages that the blood sedimentation sensor is located outside a rubber tube connected with the tail of the sampling needle 11, and a blood sample needs to be dragged into the rubber tube at the position of the blood sedimentation (ESR) detection module for measurement during testing.

Inside the sample dragged the sample to the rubber tube of sampling needle afterbody in the blood sedimentation measurement mode, because there is dead volume easily (also be difficult for the deposit that is rinsed) with sampling needle afterbody junction and is difficult to wash, and blood sample gets into in the rubber tube, the scope that the sampling channel is polluted by the blood sample is great, for the sample only in the conventional measurement mode of blood in the needle, the washing degree of difficulty of sampling channel increases, generally can increase the washing liquid measure and increase the scheme of abluent time and solve, the measuring speed of instrument can be influenced to this kind of scheme.

Therefore, the present application provides a new blood cell analyzer and a cleaning method thereof to solve the above technical problems.

Disclosure of Invention

The present invention has been made to solve at least one of the above problems. Specifically, the present invention provides a blood cell analyzer, which includes a blood sedimentation detection module, a blood routine detection module, a sampling distribution module, a mode setting module, a fluid path support module, and a control device;

the mode setting module is used for setting the working mode of the blood cell analyzer, wherein the working mode comprises one of a first mode, a second mode and a third mode, the first mode is a blood sedimentation detection mode, the second mode is a blood sedimentation detection mode, and the third mode is a blood sedimentation and blood sedimentation detection mode;

the sampling distribution module is used for collecting a blood sample and distributing the blood sample to the blood sedimentation detection module and/or the blood routine detection module;

the erythrocyte sedimentation rate detection module is used for detecting the erythrocyte sedimentation rate of the blood sample;

the blood routine detection module is used for performing blood routine detection on the blood sample;

the liquid path support module is at least used for cleaning the sampling distribution module;

the control device is in communication connection with the sampling distribution module, the blood sedimentation detection module, the blood routine detection module, the mode setting module and the fluid path support module, and is at least used for controlling at least one of the blood sedimentation detection module and the blood routine detection module to operate according to a set working mode;

the blood cell analyzer is further provided with different cleaning modes, and the control device is further used for controlling the liquid path support module to execute the corresponding cleaning mode according to the set working mode so as to clean the sampling distribution module.

In one example of the use of a magnetic resonance imaging system,

when the set working mode is the second mode or the third mode, the cleaning mode of the sampling distribution module is the first cleaning mode;

and when the set working mode is the first mode, the cleaning mode of the sampling distribution module is the second cleaning mode.

In one example of the use of a magnetic resonance imaging system,

when the set working mode is the first mode or the second mode or the third mode and the characteristic data of the blood sample is higher than a set threshold value, the cleaning mode of the sampling distribution module is a first cleaning mode;

when the set working mode is the first mode, the second mode or the third mode and the characteristic data of the blood sample is not higher than the set threshold value, the cleaning mode of the sampling distribution module is the second cleaning mode.

In still another aspect, the present invention provides a blood cell analyzer, which includes a blood sedimentation detection module, a blood routine detection module, a sampling distribution module, a fluid path support module, and a control device;

the control device is in communication connection with the sampling distribution module, the blood sedimentation detection module, the blood routine detection module and the fluid path support module, the blood cell analyzer is further provided with different cleaning modes, and the control device is at least used for controlling the fluid path support module to execute the corresponding cleaning mode according to the characteristic data of the blood sample so as to clean the sampling distribution module.

In one example, the cleaning mode of the sample distribution module is a first cleaning mode when the characteristic data of the blood sample is above a set threshold;

when the characteristic data of the blood sample is not higher than the set threshold value, the cleaning mode of the sampling distribution module is a second cleaning mode.

In one example, the first washing mode comprises at least two washing processes and the second washing mode comprises at least one washing process, wherein the first washing mode and the second washing mode have at least one identical washing process.

In one example, at least one cleaning parameter of the first cleaning mode is greater than a corresponding cleaning parameter of the second cleaning mode.

In one example, the cleaning parameters include at least one of the following: the usage amount of the cleaning liquid, the concentration of the cleaning liquid, the flow rate of the cleaning liquid and the cleaning time.

In one example, the characteristic data of the blood sample includes at least one of a viscosity, a white blood cell count, a red blood cell count, and a platelet count of the blood sample.

In one example, the sampling dispensing module further comprises a sampling needle for aspirating the blood sample, the blood sedimentation detection module comprises a detection line for providing a detection site for the blood sample, the detection line is connected with the sampling needle, and the fluid circuit support module is at least used for cleaning the sampling needle and the detection line.

Another aspect of the embodiments of the present invention provides a method for cleaning a blood cell analyzer, where the blood cell analyzer is provided with different cleaning modes, and the method includes:

the blood cell analyzer comprises a mode setting module, a control module and a display module, wherein the mode setting module sets an operating mode of the blood cell analyzer, the operating mode comprises one of a first mode, a second mode and a third mode, the first mode is a blood sedimentation detection mode, the second mode is a blood sedimentation detection mode, and the third mode is a blood sedimentation and blood sedimentation detection mode;

the sampling distribution module collects a blood sample and distributes the blood sample to the blood sedimentation detection module and/or the blood routine detection module;

according to the set working mode, the control device controls at least one of the erythrocyte sedimentation rate detection module and the blood routine detection module to operate so as to detect the erythrocyte sedimentation rate of the blood sample and/or perform blood routine detection on the blood sample;

and the control device controls the liquid path support module to execute a corresponding cleaning mode according to the set working mode so as to clean the sampling distribution module.

In one example, when the set operation mode is the second mode or the third mode, the cleaning mode of the sampling distribution module is the first cleaning mode;

In another aspect of the embodiments of the present invention, there is provided a method for cleaning a blood cell analyzer, the blood cell analyzer being provided with different cleaning modes, the method including:

the control device controls at least one of the erythrocyte sedimentation rate detection module and the blood routine detection module to operate so as to detect the erythrocyte sedimentation rate of the blood sample and/or perform the blood routine detection on the blood sample;

and the control device controls the liquid path support module to execute a corresponding cleaning mode according to the characteristic data of the blood sample so as to clean the sampling distribution module.

In one example, controlling the fluid circuit support module to execute a corresponding cleaning mode to clean the sample distribution module includes:

the control device controls the liquid path support module to execute a corresponding cleaning mode so as to clean at least a sampling needle of the sampling distribution module and a detection pipeline of the blood sedimentation detection module, wherein the detection pipeline is connected with the sampling needle.

The embodiment of the invention provides a blood cell analyzer on the other hand, which comprises a blood sedimentation detection module, a blood routine detection module, a sampling distribution module, a mode setting module, a liquid path support module and a control device;

the mode setting module is used for setting the working mode of the blood cell analyzer, wherein the working mode comprises a first mode and a second mode, the first mode is a blood routine detection mode, and the second mode is a blood sedimentation detection mode;

when the second mode is switched to the first mode, the control device controls the liquid path support module to clean the sampling distribution module.

According to the blood cell analyzer and the cleaning method thereof, different cleaning modes are adopted according to different working modes, so that the measuring speed of the blood cell analyzer is increased, cleaning reagents are consumed more reasonably, the measuring cost is saved, residual blood samples, sediments and the like in the sampling distribution module are effectively removed when the sampling distribution module is cleaned in the corresponding cleaning mode, the pollution of the blood samples to the sampling distribution module is avoided, the blood cell analyzer can conveniently measure the next blood sample, and the measuring accuracy is improved.

In addition, according to the blood cell analyzer and the cleaning method thereof of the present invention, the fluid path support module may be further controlled to execute a corresponding cleaning mode according to the characteristic data of the blood sample, so as to clean the sampling distribution module, thereby increasing the measurement speed of the blood cell analyzer and consuming a cleaning reagent (also called a cleaning solution) more reasonably, thereby saving the measurement cost, and when the sampling distribution module is cleaned in the corresponding cleaning mode, the residual blood sample and sediment in the sampling distribution module are effectively removed, thereby avoiding the contamination of the sampling distribution module by the blood sample, facilitating the next measurement of the blood sample by the blood cell analyzer, and improving the measurement accuracy.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive labor.

FIG. 1 shows a schematic view of the position of a blood sample during measurement in a blood sedimentation-containing measurement mode in an embodiment of the invention;

FIG. 2 shows a schematic block diagram of a blood cell analyzer in one embodiment of the present invention;

FIG. 3 shows a schematic block diagram of a blood cell analyzer in another embodiment of the present invention;

FIG. 4 is a flow chart showing a method of cleaning a blood cell analyzer in one embodiment of the present invention;

fig. 5 is a flowchart showing a method of cleaning the blood cell analyzer according to another embodiment of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, exemplary embodiments according to the present invention will be described in detail below with reference to the accompanying drawings. It is to be understood that the described embodiments are merely a subset of embodiments of the invention and not all embodiments of the invention, with the understanding that the invention is not limited to the example embodiments described herein. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the invention described herein without inventive step, shall fall within the scope of protection of the invention.

In the following description, numerous specific details are set forth in order to provide a more thorough understanding of the present invention. It will be apparent, however, to one skilled in the art, that the present invention may be practiced without one or more of these specific details. In other instances, well-known features have not been described in order to avoid obscuring the invention. It is to be understood that the present invention may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof. As used herein, the term "and/or" includes any and all combinations of the associated listed items.

In view of the aforementioned problem of affecting the measurement speed of an analyzer caused by washing by increasing the amount of washing liquid and increasing the time of washing, the present application provides a blood cell analyzer including a sedimentation detection module, a blood routine detection module, a sampling distribution module, a mode setting module, a liquid path support module, and a control device; the mode setting module is used for setting the working mode of the blood cell analyzer, wherein the working mode comprises one of a first mode, a second mode and a third mode, the first mode is a blood sedimentation detection mode, the second mode is a blood sedimentation detection mode, and the third mode is a blood sedimentation and blood sedimentation detection mode; the sampling distribution module is used for collecting a blood sample and distributing the blood sample to the blood sedimentation detection module and/or the blood routine detection module; the erythrocyte sedimentation rate detection module is used for detecting the erythrocyte sedimentation rate of the blood sample; the blood routine detection module is used for performing blood routine detection on the blood sample; the liquid path support module is at least used for cleaning the sampling distribution module; the control device is in communication connection with the sampling distribution module, the blood sedimentation detection module, the blood routine detection module, the mode setting module and the fluid path support module, and is at least used for controlling at least one of the blood sedimentation detection module and the blood routine detection module to operate according to a set working mode; the blood cell analyzer is further provided with different cleaning modes, and the control device is further used for controlling the liquid path support module to execute the corresponding cleaning mode according to the set working mode so as to clean the sampling distribution module.

According to the blood cell analyzer disclosed by the embodiment of the invention, different cleaning modes are adopted according to different working modes, so that the measurement speed of the blood cell analyzer is increased, the cleaning liquid is more reasonably consumed, the using amount of the cleaning liquid is saved, the measurement cost is saved, residual blood samples, sediments and the like in the sampling distribution module are effectively removed when the sampling distribution module is cleaned in the corresponding cleaning mode, the pollution of the blood samples to the sampling distribution module is avoided, the next measurement of the blood samples by the blood cell analyzer is convenient, and the measurement accuracy is improved.

In order to provide a thorough understanding of the present invention, a detailed structure will be set forth in the following description in order to explain the present invention. Alternative embodiments of the invention are described in detail below, however, the invention may be practiced in other embodiments that depart from these specific details.

Specifically, the blood cell analyzer and the cleaning method thereof according to the present application will be described in detail below with reference to the drawings. The features of the following examples and embodiments may be combined with each other without conflict.

First, a blood cell analyzer according to an embodiment of the present invention will be described with reference to fig. 2, in which fig. 2 shows a schematic block diagram of the blood cell analyzer according to an embodiment of the present invention.

As shown in fig. 2, the blood cell analyzer according to the embodiment of the present invention includes a mode setting module 60, a blood sedimentation detecting module 20, a blood routine detecting module 30, a sampling and distributing module 10, a fluid path supporting module 40, and a control device 50.

In one example, the mode setting module 60 is configured to set an operation mode of the blood cell analyzer, wherein the operation mode includes one of a first mode, a second mode and a third mode, the first mode is a blood routine testing mode, that is, when the blood cell analyzer operates in the first mode, the first mode is a blood sedimentation testing mode, that is, when the blood cell analyzer operates in the second mode, the second mode is a blood sedimentation testing mode, that is, when the blood cell analyzer operates in the second mode, the blood sedimentation testing mode is performed on the blood sample, and the third mode is a blood sedimentation and blood routine testing mode, that is, when the blood cell analyzer operates in the third mode, the blood sedimentation testing mode and the blood routine testing mode are performed on the blood sample. The mode setting module 60 may be used for receiving a mode setting operation input by a user, for example, the user selects a suitable operation mode according to a test item to be tested on the blood sample to be tested. The mode setting module can select the corresponding working mode according to the requirements of the user so as to realize the test of the corresponding test items, increase the operation flexibility of the blood cell analyzer and expand the application scene of the blood cell analyzer.

The sampling distribution module 10 is configured to collect a blood sample and distribute the blood sample to the sedimentation detection module 20 and/or the blood routine detection module 30, and specifically, the blood sample distribution manner corresponds to an operation mode, for example, when the operation mode of the blood cell analyzer is the first mode, that is, when the blood cell analyzer is used for performing blood routine detection on the blood sample, the sampling distribution module 10 is configured to collect the blood sample and distribute the blood sample to the blood routine detection module 30; for example, when the blood cell analyzer operates in the second mode and is used for performing a blood sedimentation test on a blood sample, the sampling and distributing module 10 is used for collecting the blood sample and distributing the blood sample to the blood sedimentation test module 20; for another example, when the blood cell analyzer operates in the third mode, it is used for performing a blood sedimentation test and a blood routine test on a blood sample, and the sampling and distributing module 10 is used for collecting the blood sample and distributing the blood sample to the blood sedimentation test module 20 and the blood routine test module 30.

When the blood cell analyzer is operated in the third mode, the sampling and dispensing module 10 is used for collecting a blood sample, and dispensing a first portion of the blood sample (i.e., a first portion of the blood sample) to the detection line of the blood sedimentation detection module 20 and a second portion of the blood sample (i.e., a second portion of the blood sample) to the blood routine detection module 30. In this case, the first portion and the second portion of the blood sample may be dispensed sequentially, or the first portion and the second portion of the blood sample may be dispensed simultaneously, and the order of dispensing is not limited.

The erythrocyte sedimentation rate detecting module 20 is used for detecting the erythrocyte sedimentation rate of a blood sample, and as shown in fig. 1, the erythrocyte sedimentation rate detecting module comprises a detecting pipeline 21 and an optical detecting device 22, the detecting pipeline 21 is used for providing a detecting place for the blood sample (such as the first part blood sample), and the optical detecting device 22 is used for irradiating light to the blood sample distributed in the detecting pipeline 21 and detecting the absorption or scattering degree of the light by the blood sample distributed in the detecting pipeline 21 to detect the erythrocyte sedimentation rate of the blood sample. When the erythrocyte sedimentation rate is detected by the erythrocyte sedimentation rate detection module, the blood sample in the detection pipeline 21 does not displace, namely remains still.

The optical detection device 22 includes a light emitter (not shown) and a light receiver (not shown). The light emitter and the light receiver are respectively located on both sides of the detection area of the detection pipeline 21. The light emitter is used to illuminate the blood sample in the detection zone. The light receiver is used for detecting the variation of the light emitted by the light emitter after the blood sample is irradiated by the light (for example, receiving the light transmitted and/or scattered by the blood sample), and the absorption or scattering degree of the light by the blood sample is detected by detecting the received light.

The blood routine testing module 30 is used for performing blood routine testing on the blood sample, and the blood routine testing module 30 includes a blood routine testing cell (not shown) for providing a testing place for the blood sample (such as the aforementioned second partial sample) and a blood routine testing device (not shown) for performing blood routine testing on the blood sample distributed into the blood routine testing cell.

It will be appreciated by those skilled in the art that the blood routine detection means may be an optical detection means or an impedance detection means. When the blood routine detecting module 30 performs blood routine detection on a blood sample, the blood sample and corresponding reaction reagents may be added to a blood routine detecting pool, and the blood sample in the blood routine detecting pool is measured by a blood routine detecting device to obtain at least one blood routine parameter, where the blood routine parameter may include at least one or more combinations of WBC (White blood cell) five classification results, WBC count and morphological parameters, HGB (Hemoglobin) function measurement, RBC (Red blood cell) and PLT (platelet) count and morphological parameters, and in an actual blood routine detecting process, the blood routine detecting item may be increased or decreased as needed, which is not limited herein.

The blood cell analyzer that this application embodiment provided is provided with erythrocyte sedimentation rate that erythrocyte sedimentation rate detection module 20 and conventional detection module 30 of blood can detect blood through detection pipeline 21 and optical detection device 22 to erythrocyte sedimentation rate detection module 20, conventional detection module 30 of blood can detect conventional parameter of blood, and then make the sample analyzer that this application provided can enough detect erythrocyte sedimentation rate, can detect the blood conventionality again, in clinical practical application, two blood detection items can be realized to an equipment, the function is various, it is more convenient to use.

In one example, as shown in fig. 1, the sampling and dispensing module further includes a sampling needle 11 for sucking the blood sample, the blood sedimentation detection module includes a detection line 21, the detection line 21 is used for providing a detection site for the blood sample, the detection line 21 is connected with the sampling needle 11, for example, the detection line 21 is connected with the tail of the sampling needle 11.

In one embodiment of the present application, the detection pipeline 21 is made of a flexible tube, and the detection area of the detection pipeline 21 is made of a light-transmitting material. Therefore, the detection pipeline 21 can be flexibly arranged, for example, vertically, horizontally or obliquely arranged, or also can be arranged in a bending way, which is not limited.

In one embodiment of the present application, the detection line 21 is configured as a capillary tube.

In one example, the sample distribution module further comprises a power device 12, wherein the power device 12 is connected to the detection line 21 and is used for driving a part of the blood sample (for example, the first part of the sample) to flow into the detection line 21, stopping the movement of the blood sample after the blood sample flows to the detection area, and then keeping the blood sample in the detection area. Alternatively, the detection line 21 may also be part of the sampling line of the sample distribution module.

Further, the power device 12 is used to provide negative pressure to the sampling needle to draw the blood sample and positive pressure to push out the blood sample.

After the erythrocyte sedimentation rate is detected, the power device 12 can also drive the blood sample in the detection pipeline 21 to flow so as to discharge the detection pipeline 21 to prepare for the next detection.

The power device 12 may be a pump, syringe, or other source of pressure capable of providing power.

In one example, the sampling and dispensing module may further comprise a driving device (not shown) for driving the sampling needle to move so that the sampling needle collects the blood sample and dispenses the blood sample to the detection line of the blood sedimentation detection module and/or dispenses the blood sample to the blood routine detection cell of the blood routine detection module.

For example, when the blood cell analyzer operates in the third mode, the driving means first drives the sampling needle 11 to move to the test tube loaded with the blood sample; the power device 12 provides negative pressure for the sampling needle so that the sampling needle 11 sucks the blood sample in the test tube, the driving device drives the sampling needle 11 to move to the upper part of the blood routine detection pool, the power device provides positive pressure for the sampling needle 11 so as to drop a part of the blood sample in the sampling needle 11 into the blood routine detection pool to detect the blood routine parameters, and then the power device 12 provides negative pressure for the sampling needle until the residual blood sample in the sampling needle 11 flows into the detection pipeline 21 to detect the blood sedimentation.

In another example, when the blood cell analyzer operates in the second mode, i.e., only the sedimentation test is performed, the driving means first drives the sampling needle 11 to move to the test tube loaded with the blood sample; the power unit 12 provides negative pressure to the sampling needle so that the sampling needle 11 sucks up the blood sample in the test tube and flows the blood sample into the detection line 21 to detect the blood sedimentation.

In other examples, when the blood cell analyzer operates in the first mode, i.e., detects only blood routine, the driving means first drives the sampling needle 11 to move to the test tube loaded with the blood sample; the power device 12 provides negative pressure for the sampling needle so that the sampling needle 11 sucks the blood sample in the test tube, the driving device drives the sampling needle 11 to move to the upper part of the blood routine detection pool, and the power device provides positive pressure for the sampling needle 11 so that at least part of the blood sample in the sampling needle 11 is dripped into the blood routine detection pool to detect the blood routine parameters.

The structure of the sampling allocation module described above is merely an example, and any other suitable structure of the sampling allocation module may be applied to the present application.

After the detection is finished, the blood sedimentation detection module 20 and the blood routine detection module 30 are both required to be cleaned so as to carry out the next detection, and the influence of the residue of the previous blood sample to be detected on the detection result of the next blood sample to be detected is avoided. The sample dispensing module 10 also needs to be cleaned to collect the next blood sample to be tested.

In one example, as shown in fig. 2, the blood cell analyzer further includes a fluid circuit support module 40 for at least cleaning the sample dispensing module. The fluid circuit support module 40 may also be used to provide fluid circuit support for the sample distribution module, the blood sedimentation detection module 20 and the blood routine detection module 30. Specifically, the fluid circuit support module 40 performs fluid circuit support by supplying fluid to the sampling distribution module 10, the blood sedimentation detection module 20, and the blood routine detection module 30. For example, the fluid path support module 40 may provide cleaning solutions to the sampling distribution module 10, the blood sedimentation detection module 20, and the blood routine detection module 30, respectively, so as to clean the sampling needle 11, the detection pipeline 21, the blood routine detection pool, and the like, respectively, so as to avoid polluting the blood sample to be detected and causing inaccurate detection results.

In one embodiment, the reagent sample adding, reaction mixing, measurement, cleaning and maintenance of the blood sedimentation detection module and the blood routine detection module are assisted by the liquid path support module.

In one example, the fluid circuit support module is further adapted to clean at least the sampling needle of the sampling dispensing module and the detection line of the blood sedimentation detection module.

In one embodiment, the blood cell analyzer further comprises a control device 50, wherein the control device 50 is communicatively connected with the sampling distribution module 10, the sedimentation detection module 20, the blood routine detection module 30, the mode setting module 60 and the fluid circuit support module 40, and at least used for controlling the operation of at least one of the sedimentation detection module and the blood routine detection module according to a set working mode; the blood cell analyzer is further provided with different cleaning modes, and the control device 50 is further configured to control the fluid path support module 40 to execute a corresponding cleaning mode according to the set working mode, so as to clean the sampling distribution module 10. Because the blood sample distribution modes of the specific working modes are different, the corresponding cleaning mode can be selected according to the working modes, so that the measurement speed of the blood cell analyzer is increased, the cleaning reagent is more reasonably consumed, the measurement cost is saved, residual blood samples, sediments and the like in the sampling distribution module are effectively removed when the sampling distribution module is cleaned in the corresponding cleaning mode, the pollution of the blood samples to the sampling distribution module is avoided, and the blood cell analyzer can conveniently measure the next blood sample.

The control device 50 includes at least: the device comprises a processing component, a RAM, a ROM, a communication interface, a memory and an I/O interface, wherein the processing component, the RAM, the ROM, the communication interface, the memory and the I/O interface are communicated through a bus. The processing component may be a CPU, GPU or other chip with computing capabilities. The memory stores various computer programs executed by the processing unit, such as an operating system and an application program, and data necessary for executing the computer programs. In addition, data stored locally during the sample testing process may be stored in memory, if desired.

The I/O interface is constituted by a serial interface such as USB, IEEE1394, or RS-232C, a parallel interface such as SCSI, IDE, or IEEE1284, and an analog signal interface composed of a D/a converter and an a/D converter. The I/O interface is connected with an input device consisting of a keyboard, a mouse, a touch screen or other control buttons, and a user can directly input data to the control device by using the input device. In addition, a display with a display function can be connected to the I/O interface, for example: liquid crystal screen, touch-sensitive screen, LED display screen etc. controlling means can be with the data of image display data output that the controlling means handles to the display and show, for example: analytical data, instrument operating parameters, etc. The communication interface is an interface that may be any communication protocol known at the present time. The communication interface communicates with the outside through a network. The control device may communicate data with any device connected through the network via the communication interface in a communication protocol.

In one example, the different wash modes may include a first wash mode and a second wash mode, e.g., at least one wash parameter of the first wash mode is greater than a corresponding wash parameter of the second wash mode.

Optionally, the cleaning parameters include at least one of the following parameters: the usage amount of the cleaning liquid, the concentration of the cleaning liquid, the flow rate of the cleaning liquid and the cleaning time.

In one example, when the set operation mode is the second mode or the third mode, the cleaning mode of the sampling distribution module is the first cleaning mode. Because the blood sedimentation test is required to be performed in both the second mode and the third mode, the tail part of the sampling needle 11 and the detection pipeline 21 are connected, when a blood sample is distributed to the detection pipeline 21, deposits (such as dead deposits) which are difficult to clean easily exist at the connection part of the detection pipeline 21 and the tail part of the sampling needle 11, and the blood sample enters the detection pipeline 21, and the range of the contamination of the sampling pipeline (also called as a sampling channel) of the sampling distribution module by the blood sample is large, therefore, when the set working mode is the second mode or the third mode, the cleaning mode of the sampling distribution module is the first cleaning mode, and the first cleaning mode has larger cleaning parameters than the second cleaning mode, so that the detection pipeline of the sampling distribution module (such as the sampling needle) and the blood sedimentation detection module can be cleaned more sufficiently, and the deposits at the connection part of the detection pipeline and the tail part of the sampling needle and the contamination in the sampling distribution module can be effectively removed And the dye avoids the pollution to the next blood sample to be measured, and improves the accuracy of measurement.

In another example, when the set operation mode is the first mode, that is, when the blood cell analyzer only performs routine blood detection, the cleaning mode of the sampling and distributing module is the second cleaning mode, because only the routine blood detection is performed, the sample suction amount of the blood sample is small, the blood sample does not need to be distributed to the detection pipeline of the sedimentation detection module, and only inside the sampling needle, so that the sampling pipeline (or the detection pipeline) connected with the tail part of the sampling needle is not polluted, basically no pollutant such as dead volume exists at the connection part of the tail part of the sampling needle and the detection pipeline, and the pollution range of the blood sample to the pipeline is small, the cleaning is relatively easy, at this time, the second cleaning mode is adopted for cleaning, the pollutant can be removed, and because the cleaning parameter of the second cleaning mode is smaller than that of the first cleaning mode, the routine blood measurement flow can be optimized, the measurement speed is improved, the cleaning reagent can be more reasonably consumed, and the measurement cost is saved.

In another example, when the set operation mode is the first mode or the second mode or the third mode and the characteristic data of the blood sample is higher than a set threshold, the cleaning mode of the sampling distribution module is a first cleaning mode; when the set working mode is the first mode, the second mode or the third mode and the characteristic data of the blood sample is not higher than the set threshold value, the cleaning mode of the sampling distribution module is the second cleaning mode. Optionally, the characteristic data of the blood sample comprises at least one of a viscosity, a white blood cell count, a red blood cell count, and a platelet count of the blood sample.

The characteristic data of the blood sample may be obtained based on the test results of a blood routine test, for example, white blood cell count, red blood cell count and platelet count may be obtained based on the test results of the blood routine test, and the characteristic data of the viscosity of the blood sample may be obtained based on other devices specifically used for testing the viscosity of the blood sample.

The set threshold may be any suitable value that is suitably set based on a priori experience, and is not particularly limited herein.

Because the characteristic data of the blood samples are different, the viscosity and other characteristics of the blood samples are also different, the blood samples with the characteristic data higher than a set threshold value are easier to remain in the sampling distribution module, the detection pipeline and the like, and the residual quantity is relatively large, therefore, the first cleaning mode can be used at the moment, pollutants and the like can be effectively removed, the pollution to the next blood sample to be detected is avoided, the residual quantity of the blood samples with the characteristic data higher than the set threshold value in the sampling distribution module, the detection pipeline and the like is small, the second cleaning mode can be used, the pollutants can be effectively removed, the pollution to the next blood sample to be detected is avoided, the cleaning time and the using amount of cleaning agents can be saved, and the measurement rate is improved.

In one example, the first washing mode includes at least two washing processes, the second washing mode includes at least one washing process, wherein the first washing mode and the second washing mode have at least one same washing process, optionally, the first washing mode may be a washing process performed at least once more on the basis of the second washing mode, for example, the first washing mode may include two washing processes, and the second washing mode includes one washing process, wherein one of the two washing processes of the first washing mode and the second washing mode are the same washing process, so that the first washing mode continues to perform at least one more washing process on the basis of the second washing mode, thereby more sufficiently washing the sampling distribution module, the detection pipeline and the like to further remove the residue of the blood sample, the measurement accuracy is improved.

In a specific example, the first mode, the second mode and the third mode are all defaulted to execute the second cleaning mode when the test is completed, only when the characteristic data of the blood sample is higher than the set threshold, the cleaning process is additionally performed at least once, and the second cleaning mode and the cleaning process at least once can be regarded as the first cleaning mode, so that through the setting, the cleaning solution can be more reasonably consumed, the usage amount of the cleaning solution and the cleaning time are saved, the measurement flow of the blood cell analyzer is optimized, and the measurement speed is increased.

In summary, according to the blood cell analyzer of the present invention, different cleaning modes are adopted for different working modes, so as to increase the measurement speed of the blood cell analyzer and consume cleaning reagents more reasonably, thereby saving the measurement cost, and when the sampling distribution module is cleaned in the corresponding cleaning mode, residual blood samples, deposits, and the like in the sampling distribution module are effectively removed, thereby avoiding the contamination of the sampling distribution module by the blood samples, facilitating the next measurement of the blood samples by the blood cell analyzer, and improving the measurement accuracy.

In another embodiment, as shown in fig. 3, the present invention further provides a blood cell analyzer, which may be an integrated machine capable of performing both conventional blood sedimentation and blood testing, or an analyzer capable of performing only conventional blood sedimentation or blood testing, and in this embodiment, the integrated machine is mainly taken as an example.

In one example, as shown in fig. 3, the blood cell analyzer includes a sedimentation detection module 20, a blood routine detection module 30, a sampling distribution module 10, a fluid path support module 40, and a control device 50, and the specific structure and features of each module and device may be referred to the description hereinbefore.

The blood cell analyzer comprises the sampling distribution module 10, which is used for collecting a blood sample and distributing the blood sample to the sedimentation detection module 20 and/or the blood routine detection module 30, wherein the sedimentation detection module 20 is used for detecting the erythrocyte sedimentation rate of the blood sample; the blood routine testing module 30 is used for performing blood routine testing on the blood sample.

The fluid circuit support module 40 is at least used for cleaning the sampling distribution module 10, for example, at least used for cleaning a sampling needle of the sampling distribution module 10 and a detection pipeline of a blood sedimentation detection module, the control device is in communication connection with the sampling distribution module, the blood sedimentation detection module, the blood routine detection module and the fluid circuit support module, the blood cell analyzer is further provided with different cleaning modes, and the control device is at least used for controlling the fluid circuit support module to execute a corresponding cleaning mode according to characteristic data of the blood sample so as to clean the sampling distribution module. Through according to the characteristic data of blood sample, carry out corresponding washing mode, can be more abundant wash the residue or deposit in sampling distribution module and/the detection pipeline, avoid the pollution to the blood sample of next waiting to survey, improve the accuracy that detects, can also avoid simultaneously can also saving the cleaning time to the transitional consumption of washing liquid to improve test speed.

In one example, the cleaning mode of the sample distribution module is a first cleaning mode when the characteristic data of the blood sample is above a set threshold; when the characteristic data of the blood sample is not higher than the set threshold value, the cleaning mode of the sampling distribution module is a second cleaning mode. Optionally, the characteristic data of the blood sample comprises at least one of a viscosity, a white blood cell count, a red blood cell count, and a platelet count of the blood sample.

In one example, the different wash modes may include a first wash mode and a second wash mode, e.g., at least one wash parameter of the first wash mode is greater than a corresponding wash parameter of the second wash mode. Optionally, the cleaning parameters include at least one of the following parameters: the usage amount of the cleaning liquid, the concentration of the cleaning liquid, the flow rate of the cleaning liquid and the cleaning time. For example, the first cleaning mode may use more cleaning fluid and cleaning time than the second cleaning mode, thereby more effectively removing contaminants from the sample distribution module or the like.

In summary, according to the blood cell analyzer and the cleaning method thereof of the present invention, the fluid path support module may be further controlled to execute a corresponding cleaning mode according to the characteristic data of the blood sample, so as to clean the sampling distribution module, thereby increasing the measurement speed of the blood cell analyzer and consuming a cleaning reagent (also called a cleaning solution) more reasonably, thereby saving the measurement cost, and when the sampling distribution module is cleaned in the corresponding cleaning mode, the residual blood sample and sediment in the sampling distribution module are effectively removed, thereby avoiding the contamination of the sampling distribution module by the blood sample, facilitating the next measurement of the blood sample by the blood cell analyzer, and improving the measurement accuracy.

In another example, referring to fig. 2, the blood cell analyzer includes a sedimentation detection module 20, a blood routine detection module 30, a sample distribution module 10, a fluid path support module 40, a control device 50, and a mode setting module 60, and the specific structures and features of the respective modules and devices may be referred to the foregoing description.

In one example, the mode setting module 60 is configured to set an operation mode of the blood cell analyzer, wherein the operation mode includes a first mode and a second mode, the first mode is a blood routine testing mode, that is, when the blood cell analyzer operates in the first mode, it is used for performing blood routine testing on a blood sample, and the second mode is a blood sedimentation testing mode, that is, when the blood cell analyzer operates in the second mode, it is used for performing blood sedimentation testing on the blood sample. The mode setting module 60 may be used for receiving a mode setting operation input by a user, for example, the user selects a suitable operation mode according to a test item to be tested on the blood sample to be tested. The mode setting module can select the corresponding working mode according to the requirements of the user so as to realize the test of the corresponding test items, increase the operation flexibility of the blood cell analyzer and expand the application scene of the blood cell analyzer.

However, the requirement of the sedimentation mode on the carried pollution is different from that of the conventional blood mode (for example, the requirement of the sedimentation mode on the carried pollution is low), although the sedimentation sample volume is large and the pollution range is large, the cleaning liquid volume and the cleaning time do not need to be increased during the sedimentation measurement, a conventional cleaning process can be adopted (for example, the conventional blood cleaning process is adopted), and the cleaning function of the sampling channel is added when the sedimentation mode is switched to the conventional blood mode, so that the sampling channel is cleaned before the conventional blood test.

Specifically, when switching from the second mode to the first mode, the control device 50 controls the liquid path support module 40 to purge the sampling distribution module 10.

Next, a washing method of the blood cell analyzer according to an embodiment of the present invention, which can be performed based on the aforementioned blood cell analyzer of fig. 2, will be described with reference to fig. 4.

In one example, the blood cell analyzer is provided with different washing modes, and the washing method includes the following steps S401 to S404:

first, in step S401, a mode setting module sets an operation mode of the blood cell analyzer, wherein the operation mode includes one of a first mode, a second mode, and a third mode, the first mode is a blood sedimentation regular detection mode, the second mode is a blood sedimentation detection mode, and the third mode is a blood sedimentation and blood sedimentation regular detection mode.

The mode setting module can receive mode setting operation input by a user, for example, the user selects a proper working mode according to a detection item to be detected of a blood sample to be detected. The mode setting module can select the corresponding working mode according to the requirements of the user so as to realize the test of the corresponding test items, increase the operation flexibility of the blood cell analyzer and expand the application scene of the blood cell analyzer.

Next, in step S402, the sample distribution module collects a blood sample and distributes the blood sample to the sedimentation detection module and/or the blood routine detection module.

The blood sample distribution of the sampling distribution module is different due to different working modes, for example, when the working mode of the blood cell analyzer is the first mode, that is, when the blood cell analyzer is used for performing blood routine test on a blood sample, the sampling distribution module collects the blood sample and distributes the blood sample to the blood routine test module; for example, when the working mode of the blood cell analyzer is the second mode and the blood sample is subjected to blood sedimentation detection, the sampling distribution module collects the blood sample and distributes the blood sample to the blood sedimentation detection module; for another example, when the blood cell analyzer operates in the third mode, the blood cell analyzer is configured to perform a blood sedimentation test and a blood routine test on a blood sample, and the sampling and distributing module collects the blood sample and distributes the blood sample to the blood sedimentation test module and the blood routine test module.

In one example, when the operating mode includes a blood sedimentation test, then the sample distribution module

In one example, when the blood cell analyzer operates in the third mode, the driving means of the sample dispensing module first drives the sampling needle to move to the test tube loaded with the blood sample; the power device provides the negative pressure for the sampling needle to the blood sample in the test tube is drawn up to the sampling needle, and drive arrangement drive sampling needle moves the top to the conventional detection pond of blood, and power device provides the positive pressure for the sampling needle to with partly instils into the conventional detection pond of blood of the blood sample in the sampling needle in, with the conventional parameter of detection blood, later, power device provides the negative pressure for the sampling needle until the remaining blood sample in the sampling needle flows to the detection pipeline in, with the detection erythrocyte sedimentation.

In another example, when the blood cell analyzer operates in the second mode, i.e., only a blood sedimentation test is performed, the driving means first drives the sampling needle to move to the test tube loaded with the blood sample; the power device provides negative pressure for the sampling needle so that the sampling needle sucks the blood sample in the test tube and enables the blood sample to flow into the detection pipeline to detect the blood sedimentation.

In other examples, when the blood cell analyzer operates in the first mode, i.e., only detects blood conventions, the driving means first drives the sampling needle to move to the test tube loaded with the blood sample; the power device provides negative pressure for the sampling needle so that the sampling needle sucks the blood sample in the test tube, the driving device drives the sampling needle to move to the upper part of the blood routine detection pool, and the power device provides positive pressure for the sampling needle so that at least part of the blood sample in the sampling needle is dripped into the blood routine detection pool to detect blood routine parameters.

The allocation method of the sampling allocation module is merely an example, and other suitable methods may be applied to the present application.

Next, in step S403, according to the set operation mode, the control device controls at least one of the erythrocyte sedimentation rate detection module and the blood routine detection module to operate so as to detect the erythrocyte sedimentation rate of the blood sample and/or perform the blood routine detection on the blood sample.

After the blood sample is dispensed through the sample dispensing module, a blood sedimentation test and/or the blood routine test may be performed.

When the set working mode is the first mode, the control device controls the blood routine detection module to operate so as to carry out blood routine detection on the blood sample; when the set working mode is the second mode, the control device controls the sedimentation detection module to operate so as to detect the erythrocyte sedimentation rate of the blood sample; when the set working mode is the third mode, the control device controls the sedimentation detection module and the blood routine detection module to operate so as to detect the erythrocyte sedimentation rate of the blood sample and perform blood routine detection on the blood sample.

The specific measurement method can refer to the description in the foregoing, and is not described herein again.

Finally, in step S404, the control device controls the fluid path support module to execute a corresponding cleaning mode according to the set working mode, so as to clean the sampling distribution module.

In one example, the control device controls the fluid path support module to execute a corresponding cleaning mode to clean the sampling distribution module, and the control device comprises: the control device controls the liquid path support module to execute a corresponding cleaning mode so as to clean at least a sampling needle of the sampling distribution module and a detection pipeline of the blood sedimentation detection module, wherein the detection pipeline is connected with the sampling needle.

When the set working mode is the second mode or the third mode, the cleaning mode of the sampling distribution module is the first cleaning mode; and when the set working mode is the first mode, the cleaning mode of the sampling distribution module is the second cleaning mode.

In other examples, the wash mode of the sample distribution module is a first wash mode when the characteristic data of the blood sample is above a set threshold; when the characteristic data of the blood sample is not higher than the set threshold value, the cleaning mode of the sampling distribution module is a second cleaning mode. Optionally, the characteristic data of the blood sample comprises at least one of a viscosity, a white blood cell count, a red blood cell count, and a platelet count of the blood sample.

In one example, the first cleaning mode includes at least two cleaning processes, the second cleaning mode includes at least one cleaning process, wherein the first cleaning mode and the second cleaning mode have at least one same cleaning process, optionally, the first cleaning mode may be a cleaning process performed at least one more time on the basis of the second cleaning mode, for example, the first cleaning mode may include two cleaning processes, and the second cleaning mode includes one cleaning process, wherein one of the two cleaning processes of the first cleaning mode and the second cleaning mode are the same cleaning process, so that the first cleaning mode continues at least one more cleaning process on the basis of the second cleaning mode, thereby more sufficiently cleaning the sampling distribution module, the detection pipeline, and the like, and thus, the cleaning solution can be more reasonably consumed, the using amount of the cleaning solution and the cleaning time are saved, and the like, so that the measurement flow of the blood cell analyzer is optimized, and the measurement speed is increased.

In one example, at least one cleaning parameter of the first cleaning mode is greater than a corresponding cleaning parameter of the second cleaning mode. Optionally, the cleaning parameters include at least one of the following parameters: the usage amount of the cleaning liquid, the concentration of the cleaning liquid, the flow rate of the cleaning liquid and the cleaning time. The first cleaning mode is used for more fully cleaning the sampling distribution module (such as a sampling needle) and the detection pipeline of the blood sedimentation detection module, so that the sediments at the joint of the detection pipeline and the tail part of the sampling needle and pollutants in the sampling distribution module are effectively removed, the pollution to a next blood sample to be measured is avoided, and the accuracy of measurement is improved. When the second cleaning mode is used, the cleaning parameters of the second cleaning mode are smaller than those of the first cleaning mode, so that the conventional blood measurement process can be optimized, the measurement speed is increased, the cleaning reagent can be more reasonably consumed, and the measurement cost is saved.

In summary, the cleaning method according to the embodiment of the present invention adopts different cleaning modes for different working modes, so as to increase the measurement speed of the blood cell analyzer and consume more reasonably the cleaning reagent, save the measurement cost, and effectively remove the residual blood sample and sediment in the sampling distribution module when the sampling distribution module is cleaned in the corresponding cleaning mode, thereby avoiding the contamination of the sampling distribution module by the blood sample, facilitating the next measurement of the blood sample by the blood cell analyzer, and improving the measurement accuracy.

Next, a washing method of the blood cell analyzer according to another embodiment of the present invention, which can be performed based on the aforementioned blood cell analyzer of fig. 3, will be described with reference to fig. 5.

In one example, the blood cell analyzer is provided with different washing modes, and the washing method includes the following steps S501 to S503:

in step S501, the sampling distribution module collects a blood sample, and distributes the blood sample to the sedimentation detection module and/or the blood routine detection module, which may refer to the related description in the foregoing and is not repeated herein.

In step S502, the control device controls at least one of the sedimentation detection module and the blood routine detection module to operate so as to detect the erythrocyte sedimentation rate of the blood sample and/or perform the blood routine detection on the blood sample, which may refer to the related description in the foregoing and is not repeated herein.

In step S503, the control device controls the fluid circuit support module to execute a corresponding cleaning mode according to the characteristic data of the blood sample, so as to clean the sampling distribution module.

In one example, the cleaning mode of the sample distribution module is a first cleaning mode when the characteristic data of the blood sample is above a set threshold; when the characteristic data of the blood sample is not higher than the set threshold value, the cleaning mode of the sampling distribution module is a second cleaning mode. Optionally, the characteristic data of the blood sample comprises at least one of a viscosity, a white blood cell count, a red blood cell count, and a platelet count of the blood sample. For the specific description, reference may be made to the related description in the foregoing, which is not repeated herein.

To sum up, according to the cleaning method of the embodiment, the fluid path support module is controlled to execute the corresponding cleaning mode according to the characteristic data of the blood sample, so as to clean the sampling distribution module, that is, the blood cell analyzer sets the appropriate cleaning mode according to the characteristic data of the blood sample, thereby increasing the measurement speed of the blood cell analyzer and consuming the cleaning reagent (also called cleaning solution) more reasonably, thereby saving the measurement cost, and when the sampling distribution module is cleaned in the corresponding cleaning mode, the residual blood sample and the sediment in the sampling distribution module are effectively removed, so that the blood sample is prevented from being polluted by the sampling distribution module, the blood cell analyzer can conveniently measure the next blood sample, and the measurement accuracy is improved.

Although the illustrative embodiments have been described herein with reference to the accompanying drawings, it is to be understood that the foregoing illustrative embodiments are merely exemplary and are not intended to limit the scope of the invention thereto. Various changes and modifications may be effected therein by one of ordinary skill in the pertinent art without departing from the scope or spirit of the present invention. All such changes and modifications are intended to be included within the scope of the present invention as set forth in the appended claims.

Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the implementation. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present invention.

In the several embodiments provided in the present application, it should be understood that the disclosed apparatus and method may be implemented in other ways. For example, the above-described device embodiments are merely illustrative, and for example, the division of the units is only one logical functional division, and other divisions may be realized in practice, for example, a plurality of units or components may be combined or integrated into another device, or some features may be omitted, or not executed.

In the description provided herein, numerous specific details are set forth. It is understood, however, that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures and techniques have not been shown in detail in order not to obscure an understanding of this description.

Similarly, it should be appreciated that in the description of exemplary embodiments of the invention, various features of the invention are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of streamlining the invention and aiding in the understanding of one or more of the various inventive aspects. However, the method of the present invention should not be construed to reflect the intent: that the invention as claimed requires more features than are expressly recited in each claim. Rather, as the following claims reflect, inventive aspects lie in less than all features of a single disclosed embodiment. Thus, the claims following the detailed description are hereby expressly incorporated into this detailed description, with each claim standing on its own as a separate embodiment of this invention.

It will be understood by those skilled in the art that all of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and all of the processes or elements of any method or apparatus so disclosed, may be combined in any combination, except combinations where such features are mutually exclusive. Each feature disclosed in this specification (including any accompanying claims, abstract and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise.

Furthermore, those skilled in the art will appreciate that while some embodiments described herein include some features included in other embodiments, rather than other features, combinations of features of different embodiments are meant to be within the scope of the invention and form different embodiments. For example, in the claims, any of the claimed embodiments may be used in any combination.

The various component embodiments of the invention may be implemented in hardware, or in software modules running on one or more processors, or in a combination thereof. Those skilled in the art will appreciate that a microprocessor or Digital Signal Processor (DSP) may be used in practice to implement some or all of the functionality of some of the modules according to embodiments of the present invention. The present invention may also be embodied as apparatus programs (e.g., computer programs and computer program products) for performing a portion or all of the methods described herein. Such programs implementing the present invention may be stored on computer-readable media or may be in the form of one or more signals. Such a signal may be downloaded from an internet website or provided on a carrier signal or in any other form.

It should be noted that the above-mentioned embodiments illustrate rather than limit the invention, and that those skilled in the art will be able to design alternative embodiments without departing from the scope of the appended claims. In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The invention may be implemented by means of hardware comprising several distinct elements, and by means of a suitably programmed computer. In the unit claims enumerating several means, several of these means may be embodied by one and the same item of hardware. The usage of the words first, second and third, etcetera do not indicate any ordering. These words may be interpreted as names.

Claims

1. A blood cell analyzer is characterized by comprising a blood sedimentation detection module, a blood routine detection module, a sampling distribution module, a mode setting module, a liquid path support module and a control device;

2. The blood cell analyzer of claim 1,

3. The blood cell analyzer of claim 1,

4. A blood cell analyzer is characterized by comprising a blood sedimentation detection module, a blood routine detection module, a sampling distribution module, a liquid path support module and a control device;

5. The blood cell analyzer of claim 4,

when the characteristic data of the blood sample is higher than a set threshold value, the cleaning mode of the sampling distribution module is a first cleaning mode;

6. The blood cell analyzer of claim 3 or 5, wherein the first washing mode includes at least two washing processes and the second washing mode includes at least one washing process, wherein the first washing mode and the second washing mode have at least one same washing process.

7. The hematology analyzer of claim 2, 3 or 5, wherein at least one cleaning parameter of the first cleaning mode is greater than a corresponding cleaning parameter of the second cleaning mode.

8. The hematology analyzer of claim 7, wherein the cleaning parameters include at least one of: the usage amount of the cleaning liquid, the concentration of the cleaning liquid, the flow rate of the cleaning liquid and the cleaning time.

9. The blood cell analyzer of any one of claims 3 to 5, wherein the characteristic data of the blood sample includes at least one of a viscosity, a white blood cell count, a red blood cell count, and a platelet count of the blood sample.

10. The blood cell analyzer of claim 1 or 4, wherein the sampling dispensing module further comprises a sampling needle for aspirating the blood sample, the sedimentation detection module comprises a detection line for providing a detection site for the blood sample, the detection line is connected to the sampling needle, and the fluid circuit support module is at least used for cleaning the sampling needle and the detection line.

11. A method of cleaning a blood cell analyzer, the blood cell analyzer being provided with different cleaning modes, the method comprising:

12. The cleaning method according to claim 11,

13. A method of cleaning a blood cell analyzer, wherein the blood cell analyzer is provided with different cleaning modes, the method comprising:

14. The cleaning method according to claim 11 or 13,

15. The cleaning method according to claim 11 or 13, wherein controlling the fluid circuit support module to perform a corresponding cleaning mode to clean the sample distribution module comprises:

16. A blood cell analyzer is characterized by comprising a blood sedimentation detection module, a blood routine detection module, a sampling distribution module, a mode setting module, a liquid path support module and a control device;

the sampling distribution module is used for collecting a blood sample and distributing the blood sample to the blood sedimentation detection module or the blood routine detection module;