CN114053475A - anti-HPV medical gynecological dressing - Google Patents

anti-HPV medical gynecological dressing Download PDF

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Publication number
CN114053475A
CN114053475A CN202111398584.9A CN202111398584A CN114053475A CN 114053475 A CN114053475 A CN 114053475A CN 202111398584 A CN202111398584 A CN 202111398584A CN 114053475 A CN114053475 A CN 114053475A
Authority
CN
China
Prior art keywords
hpv
medical gynecological
sodium alginate
blocking
gynecological dressing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202111398584.9A
Other languages
Chinese (zh)
Inventor
解达伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanxi Jianjianzhilu Medical Instrument Co ltd
Original Assignee
Shanxi Jianjianzhilu Medical Instrument Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanxi Jianjianzhilu Medical Instrument Co ltd filed Critical Shanxi Jianjianzhilu Medical Instrument Co ltd
Priority to CN202111398584.9A priority Critical patent/CN114053475A/en
Publication of CN114053475A publication Critical patent/CN114053475A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23Carbohydrates
    • A61L2300/232Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to a formula of an anti-HPV medical gynecological dressing. In order to solve the problem that the existing method has poor effect on treating HPV infection, the invention aims to provide a novel method for blocking HPV virus to assist treatment. The invention adopts the technical scheme that the disinfectant is prepared from sodium alginate, carbomer, triethanolamine, glycerol and the balance of purified water. The invention is used for reducing local HPV load, thereby achieving the purpose of blocking HPV infection.

Description

anti-HPV medical gynecological dressing
Technical Field
The invention relates to a formula of an anti-HPV medical gynecological dressing
Background
At present, with the increase of gynecological diseases of women, cervical cancer is more and more valued by the world and women. The main pathogenic factor for the occurrence of cervical cancer is related to the persistent infection of high-risk HPV. The HPV has more than 130 different subtypes which are determined, the infection parts of various different genotypes of viruses are different, the viruses which are easy to infect skin are low-risk viruses which often cause warts and are easy to infect cervical mucosa, and 14 types of viruses such as HPV16, HPV18, HPV52, HPV33 and the like are known. Particularly HPV types 16 and 18, are the major types responsible for more than 90% of cervical cancers.
HPV is a virus with strong harm, and at present, no very good specific medicine for treating gynecological diseases caused by HPV virus infection exists. The usual therapeutic methods are generally topical medications, such as interferons, bioprotein preparations, etc. Oral administration of Chinese medicinal materials. Topical drug therapy is administered primarily vaginally. Commonly used vaginal drug formulations, however, these dosage forms affect the drug action during use, more or less due to texture or defects in the drug itself. In addition, the method is also a method for exercising the body, reasonably eating, enhancing the resistance and clearing by the autoimmunity, but the methods have different effects due to different individual constitutions. Cannot quickly and well eliminate HPV virus.
Based on the existing problems, the invention aims to provide a novel auxiliary treatment mode for blocking HPV virus. The invention can prevent and treat female genital tract diseases caused by pathogenic bacteria, fungi and viruses, and has good effect on inhibiting HPV virus. The gel has good antibacterial effect by adopting the synergistic antibacterial effect of a plurality of bactericides, and has the killing effect on staphylococcus aureus, candida albicans, escherichia coli and the like, thereby having good antibacterial effect.
Disclosure of Invention
The invention solves the technical problem and adopts the technical scheme that the detergent is prepared from 0.2 part of sodium alginate, 0.1 part of carbomer, 0.1 part of triethanolamine, 0.1 part of glycerol and 9 parts of purified water. Filling the disposable injector.
The invention has the advantages that anions carried on the surface of sodium alginate are combined with positive charge regions of HPV capsid protein to block viruses from invading host cells of vaginal mucosa basal layers, so as to reduce local HPV load and further achieve the aim of blocking HPV infection.
Detailed Description
Step 1, adding purified water into an emulsifying pot, heating to 100 ℃ for 8-20 minutes, and cooling to 40 ℃ for 10-30 minutes.
And 2, sequentially adding glycerol and carbomer into an emulsifying pot filled with purified water, and homogenizing: the speed was 1000 rpm for 5 minutes. And then stirring: the speed 54rpm lasted 40 minutes.
Step 3, adding sodium alginate into an emulsifying pot, and homogenizing: the speed was 2000 rpm for 5 minutes. And then stirring: the speed 54rpm lasted 30 min.
Step 4, adding triethanolamine into an emulsifying pot, and homogenizing: the speed was 2000 rpm for 5 minutes. And then stirring: the speed 54rpm lasted 40 minutes. And finally, filling and finishing the processing technology.

Claims (2)

1. The medical gynecological dressing for resisting HPV is characterized in that the formula is composed of the following raw materials in parts by weight: 0.2 part of sodium alginate, 0.1 part of carbomer, 0.1 part of triethanolamine, 0.1 part of glycerol and 9 parts of purified water.
2. The anti-HPV medical gynecological dressing according to claim 1 is characterized in that the added sodium alginate has the effect of reducing the local HPV loading.
CN202111398584.9A 2021-11-24 2021-11-24 anti-HPV medical gynecological dressing Pending CN114053475A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111398584.9A CN114053475A (en) 2021-11-24 2021-11-24 anti-HPV medical gynecological dressing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202111398584.9A CN114053475A (en) 2021-11-24 2021-11-24 anti-HPV medical gynecological dressing

Publications (1)

Publication Number Publication Date
CN114053475A true CN114053475A (en) 2022-02-18

Family

ID=80276042

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202111398584.9A Pending CN114053475A (en) 2021-11-24 2021-11-24 anti-HPV medical gynecological dressing

Country Status (1)

Country Link
CN (1) CN114053475A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114699550A (en) * 2022-03-29 2022-07-05 湖南有美生物科技有限公司 anti-HPV functional gynecological dressing containing green tea exosomes and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114699550A (en) * 2022-03-29 2022-07-05 湖南有美生物科技有限公司 anti-HPV functional gynecological dressing containing green tea exosomes and preparation method thereof

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