CN114002103A - Method for analyzing liquefaction degree of semen - Google Patents
Method for analyzing liquefaction degree of semen Download PDFInfo
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- CN114002103A CN114002103A CN202111298455.2A CN202111298455A CN114002103A CN 114002103 A CN114002103 A CN 114002103A CN 202111298455 A CN202111298455 A CN 202111298455A CN 114002103 A CN114002103 A CN 114002103A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N5/00—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid
- G01N5/02—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid by absorbing or adsorbing components of a material and determining change of weight of the adsorbent, e.g. determining moisture content
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Abstract
The invention relates to a semen liquefaction degree analysis method, which comprises the following experimental steps of using auxiliary equipment to complete: (1) placing the experimental container on a weighing sensor; (2) connecting the weighing sensor with a computer; (3) collecting the initial mass m0 of the experimental container, and transmitting the initial mass m0 to a computer for recording; (4) aspirating the semen sample from the tube into a funnel; (5) opening the valve; (6) collecting total mass data (m1... mn) of the experimental container and the semen sample, which are measured by the weighing sensor and change along with time, at set fixed time intervals, and recording the total mass data; (7) calculating mass data of the semen sample (m1-m0... mn-m 0); (8) repeating the steps (1) to (7) to obtain quality data of different semen samples along with time change; (9) the invention can automatically judge the liquefaction degree of the semen and has higher detection accuracy.
Description
Technical Field
The invention relates to the technical field of semen liquefaction degree detection, in particular to a semen liquefaction degree analysis method.
Background
At present, the analysis of the liquefaction degree of the semen mainly depends on a manual analysis method: namely, a plastic suction pipe with the caliber of about 1.5mm is used for slowly sucking the semen, the length of mucus thread formed by the semen under the action of the gravity center is observed, the semen drops continuously fall normally, and the length of the mucus thread exceeds 2cm abnormally; or inserting the glass rod into semen for observation, and lifting to observe the length of mucus thread formed, wherein the length exceeding 2cm is abnormal.
The manual analysis mode not only needs to spend large manpower and material resources, but also can cause certain influence on the analysis result due to the individual difference of detection personnel, thereby increasing the risk of judgment errors.
Disclosure of Invention
The invention aims to provide a semen liquefaction degree analysis method which can automatically judge the semen liquefaction degree and replace manual judgment and analysis.
In order to achieve the above purpose, the following technical scheme is provided:
a semen liquefaction degree analysis method is characterized by comprising the following experimental steps of using auxiliary equipment to complete:
(1) placing the experimental container on a weighing sensor;
(2) connecting a data output end of the weighing sensor with a data input end of a computer;
(3) the weighing sensor acquires the initial mass m0 of the experimental container and transmits the initial mass m0 to the computer for recording;
(4) sucking a certain mass of semen sample from a test tube filled with the semen sample to a funnel with a valve at the bottom by using a pump through a hose, and aligning the bottom of the funnel to an experimental container;
(5) after the semen sample in the funnel is stable, opening the valve, and slowly flowing out the semen sample in the funnel into the experimental container under the action of self gravity;
(6) collecting total mass data (m1... mn) of the experimental container and the semen sample, which are measured by a weighing sensor and change along with time, at set fixed time intervals, and transmitting the total mass data to a computer for recording;
(7) calculating the quality data of the semen sample over time (m1-m0... mn-m 0);
(8) repeating the steps (1) to (7) to obtain quality data of different semen samples along with time;
(9) and drawing a data comparison curve graph of the calculated semen sample quality data changing along with time, and automatically judging the liquefaction degree of the semen sample by the computer through the curve graph.
Preferably, the auxiliary assembly includes computer, weighing sensor, experiment container, funnel, valve, hose, pump and test tube, the computer input is connected with weighing sensor's output electricity, the experiment container is placed on weighing sensor, the funnel sets up directly over the experiment container, the funnel bottom still is equipped with a valve, the one end of hose is inserted in the funnel, and its other end inserts in the test tube, the hose middle part still is equipped with a pump.
Preferably, the pump in the auxiliary device is a metering pump.
The invention has the beneficial effects that:
the invention utilizes natural gravity and a weighing sensor to collect the change condition of mass data in the dripping process of the semen sample, automatically judges the liquefaction degree of the semen according to the difference of the mass data, replaces manual analysis operation, reduces human errors and improves the detection accuracy.
Drawings
FIG. 1 is a graph comparing data according to the present invention;
FIG. 2 is a schematic view of an embodiment of the present invention;
the reference symbols shown in the figures are: 1-computer, 2-weighing sensor, 3-experimental container, 4-funnel, 5-valve, 6-hose, 7-pump, 8-test tube.
Detailed Description
The following describes the present design in detail with reference to the accompanying drawings.
As shown in FIGS. 1-2, a semen liquefaction degree analysis method comprises the following experimental steps completed by using auxiliary equipment:
(1) placing the experimental container 3 on the weighing sensor 2;
(2) connecting a data output end of the weighing sensor 2 with a data input end of the computer 1;
(3) the weighing sensor 2 acquires the initial mass m0 of the experimental container 3 and transmits the initial mass m0 to the computer 1 for recording;
(4) sucking a mass of semen sample from a tube 8 containing the semen sample through a hose 6 by using a pump 7 into a funnel 4 with a valve 5 at the bottom, and aligning the bottom of the funnel 4 with the experimental container 3;
(5) after the semen sample in the funnel 4 is stable, the valve 5 is opened, the pressure inside and outside the funnel 4 is equal, and the semen sample in the funnel 4 slowly flows out into the experimental container 3 under the action of self gravity;
(6) collecting total mass data (m1... mn) of the experimental container 3 and the semen sample, which are measured by the weighing sensor 2 and change along with time, at set fixed time intervals, and transmitting the total mass data to the computer 1 for recording;
(7) calculating the quality data of the semen sample over time (m1-m0... mn-m 0);
(8) repeating the steps (1) to (7) to obtain quality data of different semen samples along with time;
(9) and drawing a data comparison curve graph of the calculated semen sample quality data changing along with time, automatically judging the liquefaction degree of the semen sample by the computer 1 through the curve graph, wherein the outflow speed of the semen sample completely liquefied is high, the difference value between the measured data (m1... mn) and the initial quality m0 is large, the outflow speed of the non-liquefied semen sample is slow, and the measured data (m1... mn) can be close to the initial quality m0 in a short time under the condition of equal time intervals.
Wherein, the auxiliary assembly includes computer 1, weighing sensor 2, experiment container 3, funnel 4, valve 5, hose 6, pump 7 and test tube 8, the input of computer 1 is connected with weighing sensor 2's output electricity, experiment container 3 places on weighing sensor 2, funnel 4 sets up directly over experiment container 3, 4 bottoms of funnel still are equipped with a valve 5, a outflow for controlling semen, the one end of hose 6 is inserted in funnel 4, its other end inserts in test tube 8, 6 middle parts of hose still are equipped with a pump 7, a semen sample is used for extracting.
Wherein the pump 7 in the auxiliary device is a metering pump for quantitatively drawing the semen sample from the test tube 6 into the funnel 4.
Examples
As shown in fig. 1-2, the weighing cell 2 transmits the initial mass m0 of the experimental container 3 to the computer 1 for recording, the valve 5 is closed, a mass of semen sample is injected from the test tube 8 into the funnel 4 through the hose 6 by the pump 7, after the semen sample injected into the funnel 4 is stable, the valve 5 is opened, the semen sample in the funnel 4 flows into the experimental container 3 under the action of self gravity, the load cell 2 simultaneously collects mass data of the test receptacles 3 at set fixed time intervals (m1... mn), and transmitted to the computer 1 for recording, the computer 1 synchronously processes and calculates the acquired data, and repeating the steps to obtain quality data of different semen samples along with time change, drawing a data comparison curve graph, and obtaining the corresponding liquefaction degree of the semen samples according to the data comparison curve graph.
Claims (3)
1. A semen liquefaction degree analysis method is characterized by comprising the following experimental steps of using auxiliary equipment to complete:
(1) placing the experimental container on a weighing sensor;
(2) connecting a data output end of the weighing sensor with a data input end of a computer;
(3) the weighing sensor acquires the initial mass m0 of the experimental container and transmits the initial mass m0 to the computer for recording;
(4) sucking a certain mass of semen sample from a test tube filled with the semen sample to a funnel with a valve at the bottom by using a pump through a hose, and aligning the bottom of the funnel to an experimental container;
(5) after the semen sample in the funnel is stable, opening the valve, and slowly flowing out the semen sample in the funnel into the experimental container under the action of self gravity;
(6) collecting total mass data (m1... mn) of the experimental container and the semen sample, which are measured by a weighing sensor and change along with time, at set fixed time intervals, and transmitting the total mass data to a computer for recording;
(7) calculating the quality data of the semen sample over time (m1-m0... mn-m 0);
(8) repeating the steps (1) to (7) to obtain quality data of different semen samples along with time;
(9) and drawing a data comparison curve graph of the calculated semen sample quality data changing along with time, and automatically judging the liquefaction degree of the semen sample by the computer through the curve graph.
2. The method for analyzing the liquefaction degree of semen according to claim 1, wherein the auxiliary equipment comprises a computer, a weighing sensor, an experimental container, a funnel, a valve, a hose, a pump and a test tube, wherein the input end of the computer is electrically connected with the output end of the weighing sensor, the experimental container is placed on the weighing sensor, the funnel is arranged right above the experimental container, the bottom of the funnel is further provided with the valve, one end of the hose is inserted into the funnel, the other end of the hose is inserted into the test tube, and the middle part of the hose is further provided with the pump.
3. The method for analyzing the degree of liquefaction of semen according to claim 1, wherein the pump of the auxiliary device is a metering pump.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111298455.2A CN114002103A (en) | 2021-11-04 | 2021-11-04 | Method for analyzing liquefaction degree of semen |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111298455.2A CN114002103A (en) | 2021-11-04 | 2021-11-04 | Method for analyzing liquefaction degree of semen |
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| CN114002103A true CN114002103A (en) | 2022-02-01 |
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| CN202111298455.2A Pending CN114002103A (en) | 2021-11-04 | 2021-11-04 | Method for analyzing liquefaction degree of semen |
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Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5402240A (en) * | 1994-02-17 | 1995-03-28 | Dupree, Inc. | Sperm densimeter |
| JPH10176983A (en) * | 1996-12-16 | 1998-06-30 | Kaname Wakasugi | Rheological measuring apparatus for cement-based mixture |
| JPH1114529A (en) * | 1997-06-24 | 1999-01-22 | Kaname Wakasugi | Method and instrument for rheological measurement |
| CN101726578A (en) * | 2008-10-27 | 2010-06-09 | 深圳科瑞克医疗器械有限公司 | Microfluidic biological chip sperm quality analyser |
| CN104251823A (en) * | 2014-09-11 | 2014-12-31 | 天津起跑线生物信息技术有限公司 | Quantified measuring method for liquefying capability of seminal fluid |
| CN106645672A (en) * | 2017-02-20 | 2017-05-10 | 刘晓强 | Semen analysis system capable of accurately analyzing quality of semen |
| CN106618644A (en) * | 2017-02-17 | 2017-05-10 | 刘晓强 | Semen collection cup capable of accurately recording semen quantity |
| CN108717111A (en) * | 2018-04-24 | 2018-10-30 | 金华市人民医院 | Full-automatic sperm detection device and method |
| CN110618286A (en) * | 2019-10-11 | 2019-12-27 | 深圳市瑞图生物技术有限公司 | Sperm liquefaction degree analysis device and analysis method thereof |
| CN213030705U (en) * | 2020-04-20 | 2021-04-23 | 刘晓强 | Multifunctional semen liquefaction collection cup |
-
2021
- 2021-11-04 CN CN202111298455.2A patent/CN114002103A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5402240A (en) * | 1994-02-17 | 1995-03-28 | Dupree, Inc. | Sperm densimeter |
| JPH10176983A (en) * | 1996-12-16 | 1998-06-30 | Kaname Wakasugi | Rheological measuring apparatus for cement-based mixture |
| JPH1114529A (en) * | 1997-06-24 | 1999-01-22 | Kaname Wakasugi | Method and instrument for rheological measurement |
| CN101726578A (en) * | 2008-10-27 | 2010-06-09 | 深圳科瑞克医疗器械有限公司 | Microfluidic biological chip sperm quality analyser |
| CN104251823A (en) * | 2014-09-11 | 2014-12-31 | 天津起跑线生物信息技术有限公司 | Quantified measuring method for liquefying capability of seminal fluid |
| CN106618644A (en) * | 2017-02-17 | 2017-05-10 | 刘晓强 | Semen collection cup capable of accurately recording semen quantity |
| CN106645672A (en) * | 2017-02-20 | 2017-05-10 | 刘晓强 | Semen analysis system capable of accurately analyzing quality of semen |
| CN108717111A (en) * | 2018-04-24 | 2018-10-30 | 金华市人民医院 | Full-automatic sperm detection device and method |
| CN110618286A (en) * | 2019-10-11 | 2019-12-27 | 深圳市瑞图生物技术有限公司 | Sperm liquefaction degree analysis device and analysis method thereof |
| CN213030705U (en) * | 2020-04-20 | 2021-04-23 | 刘晓强 | Multifunctional semen liquefaction collection cup |
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Effective date of registration: 20221202 Address after: 215000 No. 88, Keling Road, science and Technology City, high tech Zone, Suzhou, Jiangsu Applicant after: Suzhou Guoke medical technology development (Group) Co.,Ltd. Address before: No.s3-1 commercial building, phase I, zone 2, Songhuajiang new town, 1228 Songjiang South Road, Fengman District, Jilin City, Jilin Province, 132000 Applicant before: Jilin Guoke Medical Technology Development Co.,Ltd. |