CN113985595B

CN113985595B - Sample irradiation device

Info

Publication number: CN113985595B
Application number: CN202111241471.8A
Authority: CN
Inventors: 程玉峰; 李玮; 王建波
Original assignee: Qilu Hospital of Shandong University
Current assignee: Qilu Hospital of Shandong University
Priority date: 2021-10-25
Filing date: 2021-10-25
Publication date: 2024-01-26
Anticipated expiration: 2041-10-25
Also published as: CN113985595A

Abstract

The present disclosure relates to a sample illumination device, comprising: a base, one side of which is fixed with an irradiator for irradiating the sample slide; the top surface of the bearing disc is uniformly distributed with a plurality of accommodating grooves for accommodating sample slide sheets along the circumferential direction, and the bearing disc is arranged on the top surface of the base and is rotationally connected with the base through a shaft rod; and one end of the driving mechanism is connected with the shaft lever and is used for driving the shaft lever to drive the bearing disc to rotate so that the accommodating grooves are rotated one by one to be positioned below the irradiator. The utility model provides a sample irradiation device is through setting up the loading tray at the top surface of base to set up a plurality of holding grooves and deposit the sample slide on the loading tray, make the loading tray rotatory through actuating mechanism's drive, make every holding groove homoenergetic rotate to the below of illuminator one by one, realized the continuous irradiation of a plurality of sample slide, guaranteed the irradiation effect, the going on of the many sample contrast experiments of being convenient for.

Description

Sample irradiation device

Technical Field

The present disclosure relates to the technical field of medical instruments, and in particular, to a sample irradiation apparatus.

Background

In the tumor diagnosis process, tissues are required to be cut from organs and tumors in a human body, the cut tissue slices are thinned and cut into a thickness of a plurality of micrometers so as to be observed under a microscope, then a pathological slide (specimen) in a state of being clamped by glass is manufactured, and then the specimen is irradiated and imaged by an irradiation device, so that the subsequent pathological diagnosis of the tumor is facilitated.

In the analysis process, in order to improve the diagnosis accuracy, a plurality of slice samples need to be subjected to test comparison, but the conventional tumor slice sample irradiation device is generally inconvenient to continuously irradiate and detect the plurality of slice samples, so that a multi-sample comparison experiment cannot be realized.

Disclosure of Invention

To solve or at least partially solve the above technical problems, the present disclosure provides a sample illumination device.

The present disclosure provides a sample illumination device, comprising:

a base, one side of which is fixed with an irradiator for irradiating the sample slide;

the top surface of the bearing disc is uniformly distributed with a plurality of accommodating grooves for accommodating sample slide sheets along the circumferential direction, and the bearing disc is arranged on the top surface of the base and is rotationally connected with the base through a shaft rod;

and one end of the driving mechanism is connected with the shaft lever and is used for driving the shaft lever to drive the bearing disc to rotate so that the accommodating grooves are rotated one by one to be positioned below the irradiator.

Optionally, an accommodating space is formed in the bearing disc, and the bottom end of the shaft rod extends into the accommodating space from the top of the bearing disc; the driving mechanism comprises a driving piece and a movable frame, wherein the driving piece and the movable frame are both arranged in the accommodating space, one end of the movable frame is connected to the driving piece, the driving piece can drive the movable frame to move, and the movable frame is meshed with the surface of the shaft rod.

Optionally, the sample irradiation device further includes a placement box for stacking a plurality of sample slides, the placement box is fixed at the other side of the base, a conveying rail is arranged at the bottom of the placement box, the sample slide at the bottommost part in the placement box is located on the conveying rail, and an opening of the conveying rail can face the accommodating groove.

Optionally, one end of the movable frame is located in the accommodating space, the other end of the movable frame extends out of the base and is located on the conveying rail, and the other end of the movable frame can move along the conveying rail so as to push the sample slide located on the conveying rail to move into the accommodating groove.

Optionally, the other end of the movable frame is provided with a push plate, the push plate is located on the conveying rail, the push plate is hinged with the other end of the movable frame, and the rotation direction of the push plate relative to the other end of the movable frame is a direction close to the accommodating groove.

Optionally, the surface of the movable frame is provided with a plurality of clamping grooves, a plurality of clamping teeth matched with the clamping grooves are uniformly distributed on the side wall of the shaft lever, and the movable frame and the shaft lever are meshed with each other through the clamping grooves and the clamping teeth;

a plurality of grooves are uniformly distributed on the side wall of the shaft rod, one end of each latch is hinged in each groove, the other end of each latch is connected to each groove through an elastic reset piece, and when the moving direction of the movable frame is the same as the set rotating direction of the bearing disc, the other end of each latch is positioned in each clamping groove; when the moving direction of the movable frame is opposite to the set rotating direction of the bearing disc, the movable frame pushes the other end of the latch to be separated from the clamping groove.

Optionally, the storage tank is close to be provided with first accommodation hole on the inside wall of axostylus axostyle, first accommodation hole sets up to be oriented the outward flange direction of loading tray extends, be provided with the discharge plate in the storage tank, at least a portion of discharge plate is located in the first accommodation hole, the discharge plate can be followed the hole extending direction of first accommodation hole removes, in order to promote be located sample slide in the storage tank is discharged.

Optionally, a fixing column is arranged at the center of the base, a first magnetic piece and a second magnetic piece are arranged on the fixing column, the first magnetic piece is arranged on one side surface of the fixing column, which is close to the feeding position of the bearing disc, the second magnetic piece is arranged on one side surface of the fixing column, which is close to the discharging position of the bearing disc, and the magnetic poles of the first magnetic piece and the second magnetic piece are opposite;

and one end of the discharge plate, which is positioned at the bottom of the first accommodating hole, is provided with a linkage magnetic piece, and the magnetic pole of the linkage magnetic piece is the same as that of the second magnetic piece.

Optionally, be provided with the gasbag on the inside wall of holding tank, the top surface of loading tray is provided with the orientation the shower nozzle of holding tank, the shower nozzle passes through the blast pipe intercommunication to the inner chamber of gasbag, so that the sample slide glass is moved to in the holding tank is to the gasbag compression, makes gas in the inner chamber passes through the shower nozzle is discharged.

Optionally, a second accommodating hole is formed in the inner side wall of the accommodating groove extending along the radial direction of the bearing disc, a limiting assembly is arranged in the second accommodating hole, and the limiting assembly abuts against the side edge of the sample slide in the accommodating groove;

the limiting assembly comprises a limiting block and an elastic guide piece, wherein the limiting block is connected to the second accommodating hole through the limiting block, and the limiting block protrudes out of the opening surface of the second accommodating hole.

Compared with the prior art, the technical scheme provided by the embodiment of the disclosure has the following advantages:

the utility model provides a sample irradiation device is provided with a base for erect the illuminator, further, be provided with a loading tray at the top surface of base, and effectively deposit a plurality of sample slide glass through a plurality of storage tanks on loading tray surface, on this basis, realize the linkage effect through actuating mechanism's driving effect, actuating mechanism and loading tray's axostylus axostyle connection promptly, thereby can drive the loading tray and rotate, make every storage tank on loading tray surface can rotate to the below of illuminator by one, the continuous irradiation of a plurality of sample slide glass has been realized, the irradiation effect of sample slide glass has been guaranteed, in order to carry out of the multi-sample contrast experiment.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the disclosure and together with the description, serve to explain the principles of the disclosure.

In order to more clearly illustrate the embodiments of the present disclosure or the solutions in the prior art, the drawings that are required for the description of the embodiments or the prior art will be briefly described below, and it will be obvious to those skilled in the art that other drawings can be obtained from these drawings without inventive effort.

FIG. 1 is a schematic view of a sample illumination device according to an embodiment of the disclosure;

FIG. 2 is a top view of a carrier platter according to an embodiment of the present disclosure;

FIG. 3 is a schematic cross-sectional view of a carrier tray according to an embodiment of the disclosure;

FIG. 4 is a schematic view of a part of the structure of the portion A in FIG. 3;

FIG. 5 is a schematic view of a placement box and a transfer rail according to an embodiment of the present disclosure;

FIG. 6 is a schematic cross-sectional view of a conveyor rail and a movable frame according to an embodiment of the disclosure;

fig. 7 is a schematic structural view of a shaft and a movable frame according to an embodiment of the present disclosure.

1, a base; 11. a bracket; 12. fixing the column; 12a, a first magnetic member; 12b, a second magnetic member; 2. an illuminator; 3. a carrying tray; 30. an accommodating space; 31. a receiving groove; 311. a second accommodation hole; 312. a limiting block; 313. an elastic guide; 314. a first accommodation hole; 315. a discharge plate; 316. a linkage magnetic member; 32. a shaft lever; 321. latch teeth; 322. a groove; 323. an elastic reset piece; 4. a display screen; 51. a driving member; 52. a movable frame; 521. a clamping groove; 53. a push plate; 6. placing a box; 61. a conveying rail; 611. a bottom chute; 612. a slideway; 7. a bracket; 81. a guide plate; 82. a collection box; 91. an air bag; 92. a spray head; 93. an exhaust pipe; 94. an air inlet pipe; 10. sample slides.

Detailed Description

In order that the above objects, features and advantages of the present disclosure may be more clearly understood, a further description of aspects of the present disclosure will be provided below. It should be noted that, without conflict, the embodiments of the present disclosure and features in the embodiments may be combined with each other.

In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present disclosure, but the present disclosure may be practiced otherwise than as described herein; it will be apparent that the embodiments in the specification are only some, but not all, embodiments of the disclosure.

In order to perform pathological diagnosis on tissue sections of tumors, a sample is usually required to be irradiated and imaged through an irradiation device, so that observation and detection are facilitated, and in order to improve diagnosis accuracy, a plurality of section samples can be irradiated at the same time in an analysis process, so that a multi-sample comparison experiment is realized. However, the conventional tumor slice sample irradiation device cannot realize continuous irradiation detection of a plurality of slice samples, and cannot meet the requirements of multiple sample comparison experiments.

Aiming at the defects, the embodiment provides the sample irradiation device, which realizes continuous irradiation detection by designing a structure capable of bearing a plurality of sample slides and enabling the sample slides to gradually move to the lower part of the irradiator in the structure driving process, thereby meeting the requirements of multiple sample comparison experiments. The concrete structure is as follows:

as shown in fig. 1 to 7, the present embodiment provides a sample irradiation apparatus including:

a base 1, one side of the base 1 is fixed with an irradiator 2 for irradiating a sample slide 10;

the bearing disc 3, the top surface of the bearing disc 3 is uniformly distributed with a plurality of containing grooves 31 for containing sample slide 10 along the circumferential direction, and the bearing disc 3 is arranged on the top surface of the base 1 and is rotationally connected with the base 1 through a shaft lever 32;

the driving mechanism has one end connected to the shaft 32, and is used for driving the shaft 32 to drive the bearing disc 3 to rotate, so that all the accommodating grooves 31 on the surface of the bearing disc 3 can rotate to the lower part of the irradiator 2 one by one.

Specifically, a bracket 11 extending upward of the base 1 is provided on one side of the base 1, and the illuminator 2 is fixed above the side of the base 1 by the bracket 11, with the illuminator 2 being directed toward the carrier tray 3. On this basis, because the sample slide 10 needs to be observed, the display screen 4 can be further erected at the uppermost part of the whole device through the bracket 11, the irradiator 2 is connected with the display screen 4, and the display screen 4 and the irradiator 2 are connected with an external power supply through device wires so as to realize the normal use of the device.

The shaft lever 32 is arranged on the central axis of the bearing plate 3, the base 1 and the bearing plate 3 are coaxial, a through hole for accommodating the shaft lever 32 is formed in the central axis position of the base 1, the bearing plate 3 is arranged on the surface of the base 1, and the shaft lever 32 is positioned in the through hole and is fixed with the base 1 through a bearing so as to realize the rotary motion of the bearing plate 3 relative to the base 1. The accommodating grooves 31 on the surface of the carrier plate 3 are distributed at positions close to the edge of the carrier plate 3, in this embodiment, the accommodating grooves 31 are inner grooves 322 with openings at the top and the side, and the number of the accommodating grooves 31 on the surface of the carrier plate 3 is four. Of course, in other embodiments, the accommodating grooves 31 may be provided in other shapes, and the number of the accommodating grooves 31 may be three or more, so long as each accommodating groove 31 can be ensured to be rotatable to be located below the illuminator 2.

The driving mechanism of the irradiation device can be driven by electric power to further drive the shaft lever 32 to rotate, so as to drive the bearing disc 3 to rotate, and realize continuous irradiation of the plurality of accommodating grooves 31.

When the device is specifically applied, the device is placed on a workbench surface, a plurality of sample plates are placed in the accommodating groove 31, then the driving mechanism is controlled to drive the shaft lever 32 to rotate, the illuminator 2 continuously irradiates a plurality of groups of samples from the upper part, and then the time and the number of samples are compared and tested.

In summary, the sample irradiation device provided in this embodiment sets up the irradiator 2 through the base 1, further is provided with a carrier plate 3 on the top surface of the base 1, and effectively stores a plurality of sample slide 10 through a plurality of accommodation grooves 31 on the surface of the carrier plate 3, on this basis, the carrier plate 3 is driven to rotate through the driving action of the driving mechanism, that is, the driving mechanism and the shaft lever 32 of the carrier plate 3 are mutually meshed to realize the linkage effect, so that each accommodation groove 31 on the surface of the carrier plate 3 can be successively rotated to the lower side of the irradiator 2, thereby realizing continuous irradiation of a plurality of sample slide 10, and guaranteeing the irradiation effect of the sample slide 10, so as to facilitate the multi-sample comparison experiment.

The bearing plate 3 is internally provided with an accommodating space 30, and the bottom end of the shaft lever 32 extends into the accommodating space 30 from the top of the bearing plate 3; the driving mechanism comprises a driving piece 51 and a movable frame 52, wherein the driving piece 51 and the movable frame 52 are both arranged in the accommodating space 30, one end of the movable frame 52 is connected to the driving piece 51, the driving piece 51 can drive the movable frame 52 to move, and the movable frame 52 is meshed with the surface of the shaft lever 32. In this embodiment, the driving member 51 may be an electric push rod, the electric push rod is fixed in the accommodating space 30, one end of the movable frame 52 is connected to the moving end of the electric push rod, and a part of the structural section of the movable frame 52 is used to engage with the surface of the shaft lever 32, so as to implement linkage.

As shown in fig. 5, in order to achieve stable stacking placement of slides for storage and loading, the sample irradiation apparatus further includes a placement box 6 for stacking a plurality of sample slides 10, the placement box 6 is fixed to the other side of the base 1, a transport rail 61 is provided at the bottom thereof, and the bottommost sample slide 10 within the placement box 6 is located on the transport rail 61, and an opening of the transport rail 61 can be directed toward the receiving groove 31. The sample slides 10 can drop down on the conveying rail 61 one by one, thereby providing conditions for subsequent feeding, and further, the conveying rail 61 can convey the sample slides 10 into the accommodating groove 31 due to the opening of the conveying rail toward the accommodating groove 31.

In the present embodiment, the tray 7 may be fixed to the other side of the base 1, the placement cassette 6 may be lifted to the side of the carrier tray 3 by the tray 7, the conveying rail 61 may be provided in an integrated structure with the placement cassette 6, and the extending direction of the conveying rail 61 may be set in a horizontal direction and may be brought into contact with the side opening of the accommodating groove 31 on the surface of the carrier tray 3.

Further, one end of the movable frame 52 of the driving mechanism is located in the accommodating space 30, the other end of the movable frame 52 extends out of the base 1 and is located on the conveying rail 61, and the other end of the movable frame 52 can move along the conveying rail 61 to push the sample slide 10 located on the conveying rail 61 to move into the accommodating groove 31. By means of the arrangement, the movable frame 52 can be driven by the electric push rod to reciprocate in the horizontal direction, so that the other end of the movable frame 52 can push the sample slide 10 positioned at the lowest layer of the placement box 6, namely positioned on the surface of the conveying rail 61, into the accommodating groove 31 along the extending direction of the conveying rail 61, and automatic feeding of the sample slide 10 is achieved.

The electric push rod can be controlled by the main control system of the irradiation device to set the moving distance of the push rod, so that the sample slide 10 just moves to be completely positioned in the accommodating groove 31, and can be manually controlled to ensure the accuracy degree of the moving process.

As shown in fig. 6, in the present embodiment, the other end of the movable frame 52 is further provided with a push plate 53, the push plate 53 is located on the conveying rail 61, the push plate 53 is hinged with the other end of the movable frame 52, and the rotation direction of the push plate 53 with respect to the other end of the movable frame 52 is a direction approaching the accommodating groove 31, and the rotation angle of the push plate 53 with respect to the other end of the movable frame 52 is not less than 90 degrees. The push plate 53 is arranged on the conveying rail 61, so that the push plate 53 can be abutted against the side of the sample slide 10 to push the sample slide 10, and further, the rotation direction of the push plate 53 relative to the other end of the movable frame 52 is the direction close to the accommodating groove 31, so that the push plate 53 can be kept in an upright state in the process of moving close to the carrying disc 3, the slide can be pushed and fed, and when the slide returns to move, the slide can automatically rotate under the interference action of the sample slide 10, so that the reset of the movable frame 52 is prevented from being influenced.

After the movable frame 52 is reset, the push plate 53 is also restored to the upright state so as to facilitate the next loading, for example, in this embodiment, a torsion spring is disposed at the hinge of the push plate 53 and the movable frame 52, and after the movable frame 52 is moved and reset, the push plate 53 can be rotated and reset under the action of the elasticity of the torsion spring so as to prepare for the next pushing of the sample slide 10.

In order to facilitate the cooperation of the push plate 53 and the conveying rail 61, a bottom chute 611 may be disposed at the bottom of the conveying rail 61, a slide way 612 is disposed at the top of the conveying rail 61 for carrying the sample slide 10, and the width of the bottom chute 611 communicated below the slide way 612 is smaller than the width of the slide, as shown in fig. 5, so as to ensure the moving space of the push plate 53 and the stability of the moving direction of the sample slide 10. Of course, only one arrangement of the conveying rail 61 is provided in the present embodiment, and in other embodiments, the structure of the conveying rail 61 may be changed and adjusted while ensuring stable movement of the sample slide 10.

When the electric push rod drives the movable frame 52 to move and reset, the movable frame 52 can synchronously drive the shaft rod 32 and the bearing disc 3 to rotate, specifically, as shown in fig. 7, a plurality of clamping grooves 521 can be formed on the surface of the movable frame 52, a plurality of clamping teeth 321 matched with the clamping grooves 521 are uniformly distributed on the side wall of the shaft rod 32, a plurality of grooves 322 are uniformly distributed on the side wall of the shaft rod 32, one end of each clamping tooth 321 is hinged in each groove 322, and the other end of each clamping tooth 321 is connected to each groove 322 through an elastic reset piece 323; when the moving direction of the movable frame 52 is the same as the set rotating direction of the carrying disc 3, the other end of the latch 321 extends out of the groove 322 and is matched with the clamping groove 521, and the movable frame 52 drives the carrying disc 3 to rotate; when the moving direction of the movable frame 52 is opposite to the set rotating direction of the carrying disc 3, the movable frame 52 pushes the other end of the latch 321 to rotate until being located in the groove 322, the elastic restoring member 323 is in a compressed state, and the carrying disc 3 does not rotate.

Through this setting mode, can make the movable frame 52 drive axostylus axostyle 32 and loading tray 3 in reciprocating motion in-process and carry out unidirectional rotation to realize carrying out automatic transposition to the storage tank 31 of radiator 2 below, make the device carry out continuous irradiation, handling to different samples, effectively improved the irradiation efficiency of device.

In this embodiment, the movable frame 52 may be configured such that, during the process of pushing the sample slide 10 into the accommodating groove 31, the latch 321 rotates to be located in the groove 322 due to the pushing of the movable frame 52, and the elastic reset piece 323 is compressed, so that the carrying tray 3 does not rotate along with the pushing; when the movable frame 52 moves and resets, it can drive the shaft lever 32 to rotate along the set rotation direction, and the latch 321 can be matched with the slot 521 on the surface of the movable frame 52, i.e. the elastic reset member 323 pushes the latch 321 to return to the clamped state, and the other end of the latch 321 extends out of the groove 322, where the elastic reset member 323 can adopt a reset spring, and other elastic members, such as a spring sheet or an air cushion, can also be adopted in other embodiments.

In addition, it should be emphasized that, after the movable frame 52 pushes the carrying tray 3 to rotate, it is necessary to ensure a stop position of the carrying tray 3 after rotation each time the movable frame 52 performs a subsequent pushing operation, and the side opening of the accommodating groove 31 is kept in contact with the opening of the conveying rail 61, so as to avoid affecting the placement of the subsequent sample slide 10.

After the sample slide 10 is pushed into the accommodating groove 31, the sample slide 10 needs to be kept fixed, for example, in this embodiment, a second accommodating hole 311 is provided on an inner side wall of the accommodating groove 31 extending along a radial direction of the carrying disc 3, and a limiting component is provided in the second accommodating hole 311 and abuts against a side edge of the sample slide 10 located in the accommodating groove 31, so as to clamp the sample slide 10. Further, the limiting assembly includes a limiting block 312 and an elastic guide 313, the limiting block 321 protrudes out of the opening surface of the second accommodating hole 311, the limiting block 312 is connected with the second accommodating hole 311 through the elastic guide 313, when the sample slide 10 is placed in the accommodating groove 31, the top of the limiting block 312 abuts against the side edge of the sample slide 10, and the elastic guide 313 is in a compressed state.

In order to avoid that the arrangement of the stopper 312 affects the smooth insertion of the sample slide 10, an end surface of the stopper 312 facing the accommodation groove 31 may be provided as an inclined surface inclined in a direction of being inclined toward a side away from the second accommodation hole 311 in an outward-inward direction of the carrier tray 3. The edge of the limiting block 312 is connected with the elastic guide 313 by a guide block for guiding movement, and the elastic guide 313 can be a return spring.

Through the setting of stopper 312 for sample slide 10 is in pushing in the holding tank 31 after, stopper 312 can carry out the centre gripping fixed to sample slide 10 under the elasticity effect of elastic guide 313, thereby avoids sample slide 10 to take place the position offset in the irradiation process and influences imaging. In this embodiment, in order to ensure that the forces on both sides of the slide are uniform, a structure of a stopper 312 and a second receiving hole 311 with opposite positions may be disposed on the opposite sidewalls of the receiving slot 31.

When the continuous irradiation is completed on the plurality of sample slides 10, the sample slides need to be removed, in this embodiment, a first accommodating hole 314 is provided on an inner side wall of the accommodating groove 31 near the shaft lever 32, the hole extending direction of the first accommodating hole 314 is a direction towards the peripheral edge of the carrying disc 3, an exhaust plate 315 is provided in the accommodating groove 31, at least a part of the exhaust plate 315 is located in the first accommodating hole 314, and the exhaust plate 315 can move along the hole extending direction of the first accommodating hole 314 to push the sample slide 10 located in the accommodating groove 31 to be exhausted.

On this basis, a guide plate 81 can be arranged at the unloading position of the bearing plate 3, the guide plate 81 is fixedly arranged on the side face of the base 1, the guide plate 81 is obliquely arranged in an extending mode, one end of the top of the guide plate is close to the side opening of the containing groove 31, and a collecting box 82 is arranged at one end of the bottom of the guide plate, and is used for collecting the sample slide 10 after irradiation.

In order to realize automatic operation of slide collection, in this embodiment, a fixed column 12 is disposed at a central position of the base 1, a first magnetic member 12a and a second magnetic member 12b are disposed on the fixed column 12, the first magnetic member 12a is disposed at a feeding position of the fixed column 12 near the carrying tray 3, that is, a side surface of an opening of the conveying rail 61, the second magnetic member 12b is disposed at a side surface of the fixed column 12 near a discharging position of the carrying tray 3, and magnetic poles of the first magnetic member 12a and the second magnetic member 12b are opposite; the end of the discharge plate 315 at the bottom of the first receiving hole 314 is provided with a linkage magnetic member 316, and the magnetic pole of the linkage magnetic member 316 is identical to the magnetic pole of the second magnetic member 12 b.

Through the arrangement, when the discharge plate 315 rotates to the discharge position along with the bearing disc 3, the mutual exclusion between the like magnetic poles of the linkage magnetic piece 316 and the second magnetic piece 12b moves towards the direction away from the fixed column 12, so that the sample slide 10 in the accommodating groove 31 is pushed to fall on the guide plate 81, and then automatically falls into the collecting box 82 through the guide of the guide plate 81, thereby facilitating the recovery of samples by staff and reducing the subsequent manual operation workload of the staff; during subsequent continued rotation of the carrier tray 3, the ejector plate 315 returns to be positioned within the first receiving aperture 314 due to the opposite attraction between the cooperating magnetic element 316 and the first magnetic element 12a, facilitating subsequent placement of the sample slide 10.

In this embodiment, a concave hole is formed in the central position of the carrier plate 3, the fixing column 12 is suspended by the bracket 11 and is located at the position of the concave hole, a gap is formed between the outer surface of the fixing column 12 and the inner side wall of the concave hole, so as to avoid friction between the two, and the positions of the first magnetic element 12a and the second magnetic element 12b on the surface of the fixing column 12 are set to form an included angle of 90 degrees according to the rotation direction of the carrier plate 3. Of course, in other embodiments, the first magnetic member 12a and the second magnetic member 12b may be disposed at other positions according to different arrangement manners of the devices and the rotation direction of the carrier plate 3.

Because the surface of the slide may be contaminated with dirt and impurities during the storage process of the sample, if the slide is not cleaned, the subsequent irradiation effect is affected, and further the test judgment is affected, according to the above problem, the sample irradiation device provided by the embodiment is further provided with an air bag 91 on the side wall of the accommodating groove 31, a spray head 92 is arranged on the top surface of the carrying tray 3, the spray head 92 is communicated to the inner cavity of the air bag 91 through an exhaust pipe 93, and the spray head 92 faces the top surface of the accommodating groove 31; when the sample slide 10 moves into the receiving groove 31, the balloon 91 is compressed, and the gas in the cavity is discharged through the nozzle 92. The air bag 91 can store air and can discharge the air through the nozzle 92 after compression, and the nozzle 92 further blows impurities on the surface of the sample slide 10 in the accommodating groove 31 to ensure the subsequent irradiation effect.

In order to automatically supplement the gas in the air bag 91 and avoid the backflow of the gas, in this embodiment, the air bag 91 is communicated with an air inlet pipe 94 and an air outlet pipe 93, the air inlet pipe 94 and the air outlet pipe 93 are in unidirectional circulation, the other end of the air outlet pipe 93 is connected to the spray head 92, and the other end of the air inlet pipe 94 is connected to the outside. On this basis, in order to make the gas in the gasbag 91 can be automatically replenished and discharged, the gasbag 91 can be arranged at the bottom of the limiting block 312, so that when the sample slide 10 is pushed into the accommodating groove 31, the limiting block 312 is extruded, and the gas in the gasbag 91 can be triggered to be discharged through the spray head 92, the matching effect of the whole process is better, and the automation effect is more satisfied. In order to make the dust on the surface of the sample slide 10 have a better cleaning effect, the arrangement mode of the limiting block 312 can be matched, two air bags 91 and two spray heads 92 are synchronously arranged on two opposite side walls of the accommodating groove 31, and of course, in other embodiments, the air bags 91 and the limiting block 312 can be separately arranged, or only one air bag 91 is arranged.

Through the above-mentioned structure setting of this embodiment, this sample irradiation apparatus accessible following operation realizes better result of use when using:

the plurality of groups of sample slide 10 are stacked and placed in the placement box 6, then the driving piece 51, namely the electric push rod drives the movable frame 52 and the push plate 53 to move, the push plate 53 can automatically push out the sample slide 10 to finish feeding, so that the sample slide 10 is positioned in the accommodating groove 31, at the moment, the limiting block 312 can clamp the sample slide 10 under the elastic action of the elastic guide 313, the sample slide 10 is prevented from shaking and shifting in the irradiation process, meanwhile, fibers can squeeze the air bag 91 in the elastic stretching process, so that gas in the air bag 91 enters the spray head 92 through the exhaust pipe 93, and the gas is uniformly sprayed to the surface of the sample slide 10 through the spray head 92, and therefore the surface of the sample slide 10 is automatically cleaned, and the subsequent irradiation effect is ensured; in addition, the movable frame 52 drives the carrying tray 3 to synchronously rotate in the resetting process, so that the position of the accommodating groove 31 is adjusted, the irradiator 2 can continuously irradiate a plurality of groups of sample slide 10, and further a multi-sample comparison experiment is realized, meanwhile, in the rotating process of the carrying tray 3, the discharge plate 315 can automatically push the irradiated sample slide 10 into the collecting box 82 for collection under the action of magnetic force, so that the irradiation efficiency and the use convenience of the device are effectively improved, and a series of work of the irradiation device is completed.

It should be noted that in this document, relational terms such as "first" and "second" and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.

The foregoing is merely a specific embodiment of the disclosure to enable one skilled in the art to understand or practice the disclosure. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the disclosure. Thus, the present disclosure is not intended to be limited to the embodiments shown and described herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A sample illumination device, comprising:

a base (1), wherein an illuminator (2) for illuminating a sample slide (10) is fixed on one side of the base (1);

the bearing disc (3) is characterized in that a plurality of accommodating grooves (31) for accommodating sample slide sheets (10) are uniformly distributed on the top surface of the bearing disc (3) along the circumferential direction, and the bearing disc (3) is arranged on the top surface of the base (1) and is rotationally connected with the base (1) through a shaft lever (32);

one end of the driving mechanism is connected with the shaft lever (32) and is used for driving the shaft lever (32) to drive the bearing disc (3) to rotate so that the accommodating grooves (31) are rotated one by one to be positioned below the irradiator (2);

the inside of the bearing disc (3) is provided with a containing space (30), the bottom end of the shaft lever (32) extends into the containing space (30) from the top of the bearing disc (3), and the driving mechanism is arranged in the containing space (30) and connected with the bottom end of the shaft lever (32);

the driving mechanism comprises a driving piece (51) and a movable frame (52), one end of the movable frame (52) is connected to the driving piece (51), the driving piece (51) can drive the movable frame (52) to move, and the movable frame (52) is meshed with the surface of the shaft rod (32); a plurality of clamping grooves (521) are formed in the surface of the movable frame (52), a plurality of clamping teeth (321) matched with the clamping grooves (521) are uniformly distributed on the side wall of the shaft lever (32), and the movable frame (52) and the shaft lever (32) are meshed with each other through the clamping grooves (521) and the clamping teeth (321);

a plurality of grooves (322) are uniformly distributed on the side wall of the shaft lever (32), one end of each latch (321) is hinged in each groove (322), the other end of each latch (321) is connected to each groove (322) through an elastic reset piece (323), and when the moving direction of the movable frame (52) is the same as the set rotating direction of the bearing disc (3), the other end of each latch (321) is positioned in each clamping groove (521); when the moving direction of the movable frame (52) is opposite to the set rotating direction of the bearing disc (3), the movable frame (52) pushes the other end of the latch (321) to be separated from the clamping groove (521).

2. Sample illumination device according to claim 1, characterized in that it further comprises a placement box (6) for stacking several of the sample slides (10), the placement box (6) being fixed on the other side of the base (1), the bottom of the placement box (6) being provided with a transport rail (61), and the bottom-most sample slide (10) within the placement box (6) being located on the transport rail (61), the opening of the transport rail (61) being capable of facing the receiving groove (31).

3. The sample irradiation device according to claim 2, wherein one end of the movable frame (52) is located in the accommodating space (30), the other end of the movable frame (52) extends out of the base (1) and is located on the conveying rail (61), and the other end of the movable frame (52) is movable along the conveying rail (61) to push the sample slide (10) located on the conveying rail (61) to move into the accommodating groove (31).

4. A sample irradiation apparatus according to claim 3, wherein the other end of the movable frame (52) is provided with a push plate (53), the push plate (53) is located on the conveying rail (61), the push plate (53) is hinged with the other end of the movable frame (52), and the direction of rotation of the push plate (53) with respect to the other end of the movable frame (52) is a direction approaching the accommodation groove (31).

5. Sample irradiation device according to claim 1, wherein a first receiving hole (314) is provided on an inner side wall of the receiving groove (31) close to the shaft (32), the first receiving hole (314) is provided to extend toward an outer edge direction of the carrying tray (3), an ejection plate (315) is provided in the receiving groove (31), at least a part of the ejection plate (315) is located in the first receiving hole (314), and the ejection plate (315) is movable along a hole extending direction of the first receiving hole (314) to push the sample slide (10) located in the receiving groove (31) to be ejected.

6. The sample irradiation device according to claim 5, wherein a fixed column (12) is provided at a center position of the base (1), a first magnetic member (12 a) and a second magnetic member (12 b) are provided on the fixed column (12), the first magnetic member (12 a) is provided on a side surface of the fixed column (12) near a loading position of the carrier plate (3), the second magnetic member (12 b) is provided on a side surface of the fixed column (12) near a discharging position of the carrier plate (3), and magnetic poles of the first magnetic member (12 a) and the second magnetic member (12 b) are opposite;

one end of the discharge plate (315) located at the bottom of the first accommodating hole (314) is provided with a linkage magnetic piece (316), and the magnetic pole of the linkage magnetic piece (316) is the same as the magnetic pole of the second magnetic piece (12 b).

7. Sample irradiation device according to any one of claims 1-6, wherein an air bag (91) is provided on the inner side wall of the receiving well (31), a nozzle (92) facing the receiving well (31) is provided on the top surface of the carrying tray (3), and the nozzle (92) is communicated to the inner cavity of the air bag (91) through an exhaust pipe (93), so that the air bag (91) is compressed when the sample slide (10) moves into the receiving well (31), and the air in the inner cavity is discharged through the nozzle (92).

8. The sample irradiation device according to any one of claims 1 to 6, wherein a second receiving hole (311) is provided on an inner side wall of the receiving groove (31) extending in a radial direction of the carrying tray (3), and a limiting assembly is provided in the second receiving hole (311) and abuts against a side edge of the sample slide (10) located in the receiving groove (31);

the limiting component comprises a limiting block (312) and an elastic guide piece (313), the limiting block (312) is connected to the second accommodating hole (311) through the limiting block (312), and the limiting block (312) protrudes out of the opening surface of the second accommodating hole (311).