CN113975195A - Biodegradable cleaning agent for teeth - Google Patents
Biodegradable cleaning agent for teeth Download PDFInfo
- Publication number
- CN113975195A CN113975195A CN202111309415.3A CN202111309415A CN113975195A CN 113975195 A CN113975195 A CN 113975195A CN 202111309415 A CN202111309415 A CN 202111309415A CN 113975195 A CN113975195 A CN 113975195A
- Authority
- CN
- China
- Prior art keywords
- polylactic acid
- teeth
- agent
- particles
- isomeric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000012459 cleaning agent Substances 0.000 title claims abstract description 26
- 229920000747 poly(lactic acid) Polymers 0.000 claims abstract description 27
- 239000004626 polylactic acid Substances 0.000 claims abstract description 27
- 239000002131 composite material Substances 0.000 claims abstract description 24
- 239000002245 particle Substances 0.000 claims abstract description 18
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims abstract description 16
- 238000002156 mixing Methods 0.000 claims abstract description 13
- 239000000796 flavoring agent Substances 0.000 claims abstract description 10
- 235000013355 food flavoring agent Nutrition 0.000 claims abstract description 10
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 9
- 238000013012 foaming technology Methods 0.000 claims abstract description 9
- 238000002844 melting Methods 0.000 claims abstract description 8
- 230000008018 melting Effects 0.000 claims abstract description 8
- 239000004408 titanium dioxide Substances 0.000 claims abstract description 8
- 235000003392 Curcuma domestica Nutrition 0.000 claims abstract description 7
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- 235000013976 turmeric Nutrition 0.000 claims abstract description 7
- 239000001052 yellow pigment Substances 0.000 claims abstract description 7
- 238000001035 drying Methods 0.000 claims abstract description 5
- 238000002360 preparation method Methods 0.000 claims abstract description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000000463 material Substances 0.000 claims abstract description 4
- 239000001054 red pigment Substances 0.000 claims abstract description 4
- SWGJCIMEBVHMTA-UHFFFAOYSA-K trisodium;6-oxido-4-sulfo-5-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2-sulfonate Chemical compound [Na+].[Na+].[Na+].C1=CC=C2C(N=NC3=C4C(=CC(=CC4=CC=C3O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C(S([O-])(=O)=O)C2=C1 SWGJCIMEBVHMTA-UHFFFAOYSA-K 0.000 claims abstract description 4
- 229920001661 Chitosan Polymers 0.000 claims description 18
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 13
- 244000163122 Curcuma domestica Species 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
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- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 2
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- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 description 1
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- AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 1
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- ZHNUHDYFZUAESO-UHFFFAOYSA-N formamide Substances NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 1
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Abstract
The invention relates to the technical field of tooth cleaning agents, in particular to a biodegradable cleaning agent for teeth, which comprises the following preparation steps: firstly, obtaining hollow isomeric composite polylactic acid particles by using a foaming technology, and drying the particles in a vacuum state; secondly, completely dissolving the dried particles of the hollow isomeric composite polylactic acid in absolute ethyl alcohol edible toner titanium dioxide and an edible flavoring agent; and step three, adding turmeric natural yellow pigment and purple red pigment. And step four, finally, adding the mixed materials in the step two into a melting mixer, and melting and blending for 2-10 min at the temperature of 110-180 ℃ and the rotating speed of 20-120 rpm. According to the invention, by utilizing the friction motion, the particles impact dirt in the movement process, and the cleaning of the dental dirt and dental plaque is accelerated, so that the staining factor is attached to the surface of the tooth, the effect of staining the tooth is achieved, and the staining agent is green, environment-friendly, nontoxic and non-irritant.
Description
Technical Field
The invention relates to the technical field of tooth cleaning agents, in particular to a biodegradable cleaning agent for teeth.
Background
Generally, a tooth is composed of an inner dentin (dentin) and an outer enamel (enamel) layer. The yellowing of teeth is caused by deposition of a substance having a chromophore (e.g., a double bond) originating from a foreign substance such as food on an outer enamel layer of the teeth ("intrinsic factor"), and discoloration of the teeth caused by adhesion of scales and soft deposits to the tooth surface ("extrinsic factor"). Discoloration of teeth caused by external factors is easily solved by brushing teeth, but discoloration of teeth caused by internal factors cannot be solved by using toothpaste or brushing teeth. Therefore, the toothpaste has limited effect on whitening teeth.
Under such circumstances, tooth whitening techniques using hydrogen peroxide solutions have been developed. In 1960, an american dentist treated his gums in an unexpected and unexpected fashion to find that hydrogen peroxide solution whitened teeth, resulting in the development of tooth whitening articles. In the 1980 s, a household tooth whitening device was developed. These tooth whitening devices are products containing hydrogen peroxide or formamide peroxide gel in a tray. However, the device has many safety problems in the oral cavity because peroxide must be used in high concentration and the tray causes physical irritation to the gums. After that, many attempts have been made to overcome the disadvantages of the household tooth whitening devices. For example, dental strips (dentalslips) containing low concentrations of peroxide and liquid products that can be applied directly to teeth have been developed. Liquid products have the advantage of being easy to use and disperse easily over the particular parts of the teeth desired by the user; it has the following disadvantages: such as its tendency to adhere to teeth and soft tissues of the oral cavity, such as lips, causing irritation, and being easily diluted by saliva, allowing hydrogen peroxide to be absorbed more into the teeth, resulting in a tooth whitening effect,
the method for whitening the teeth is easy to corrode the outer layer of the tooth structure in a certain amount in practical application, so that the tooth surface is easy to discolor after long-time use, and a plurality of micro pits are formed, so that the integral brightness is influenced.
The present invention has been made in view of this situation.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a biodegradable cleaning agent for teeth.
In order to achieve the purpose, the invention adopts the following technical scheme:
a biodegradable cleaning agent for teeth, comprising the following preparation steps:
firstly, obtaining hollow isomeric composite polylactic acid particles by using a foaming technology, and drying the particles in a vacuum state;
secondly, completely dissolving the dried particles of the hollow isomeric composite polylactic acid in absolute ethyl alcohol edible toner titanium dioxide and an edible flavoring agent;
and step three, adding turmeric natural yellow pigment and purple red pigment.
And step four, finally, adding the mixed materials in the step two into a melting mixer, and melting and blending for 2-10 min at the temperature of 110-180 ℃ and the rotating speed of 20-120 rpm.
Further, the hollow isomeric composite polylactic acid obtained by the foaming technology is subjected to nano-micronization, O-carboxymethyl chitosan, edible toner and edible toner are added to obtain powder or gel to form a gelatinous substance, and the concentration of the O-carboxymethyl chitosan (O-CMCS) solution is 0.4-1.6 mg/mL, so that O-CMCS nanoparticles with the particle size mainly distributed in 370-710 nm are generated when the concentration of the O-carboxymethyl chitosan (O-CMCS) solution is 1.0 mg/mL.
Furthermore, the toner titanium dioxide is prepared by mixing biodegradable cleaning agents which can obtain fruit flavor type from strawberries, durian, lemon, mango, banana, juicy peach, apple, bergamot pear and candied date.
Further, the isomeric composite polylactic acid (4-6 components), the O-carboxymethyl chitosan (2-3 components), the hydrogen peroxide solution (2-3 components) and the edible flavoring agent are mixed to form the cleaning agent, and the toothpaste product is prepared.
Furthermore, a brightening agent and an anti-wear agent are added into the isomeric composite polylactic acid.
Compared with the prior art, the invention provides the biodegradable cleaning agent for the teeth, which has the following beneficial effects:
the biodegradable cleaning agent for teeth is prepared by performing nano-micronization on hollow heterogeneous composite polylactic acid obtained by adopting a foaming technology, adding O-carboxymethyl chitosan, edible toner and edible toner to obtain powder or adding gel to generate a gel-like substance.
This a biodegradable cleaner for tooth, natural yellow pigment are fresh ginger preparation, and turmeric is the natural yellow pigment that the turmeric formed through the finish machining with the raw materials, have special fragrant smell, and the yellow pigment that contains in the turmeric rhizome, the diketone pigment that is rare in the plant world, can promote the experience in the in-service use and adopt natural ginger simultaneously, have the quick advantage of degradation.
The biodegradable cleaning agent for the teeth is added with the brightening agent and the wear-resisting agent through the structural composite polylactic acid, protects the surface of the teeth from being corroded by bacteria and prevents the surface of the teeth from being dyed by colored food, and has the advantages of biodegradation, environmental protection, no toxicity, good biocompatibility, simple operation of dentists and self operation according to instructions.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the attached tables in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
A biodegradable cleaning agent for teeth, comprising the following preparation steps:
firstly, obtaining hollow isomeric composite polylactic acid particles by using a foaming technology, and drying the particles in a vacuum state;
secondly, completely dissolving the dried particles of the hollow isomeric composite polylactic acid in absolute ethyl alcohol edible toner titanium dioxide and an edible flavoring agent;
and step three, adding turmeric natural yellow pigment and purple red pigment.
And step four, finally, adding the mixed materials in the step two into a melting mixer, and melting and blending for 2-10 min at the temperature of 110-180 ℃ and the rotating speed of 20-120 rpm.
Performing nano-micronization on hollow isomeric composite polylactic acid obtained by using a foaming technology, adding O-carboxymethyl chitosan, an edible toner and an edible toner to obtain powder or adding a gel-like substance generated by gel, wherein the concentration of the O-carboxymethyl chitosan (O-CMCS) solution is 0.4-1.6 mg/mL, so that O-CMCS nanoparticles with the particle size mainly distributed in 370-710 nm are generated when the concentration of the O-carboxymethyl chitosan (O-CMCS) solution is 1.0mg/mL, synthesizing stereoisomeric polylactic acid by using Hexamethylene Diisocyanate (HDI), polylactic acid diol (PLA-OH) and polycaprolactone diol (PCL-OH) as monomers by using the foaming technology, preparing nano-micronization by using the stereocomplex effect among enantiomers of the hollow isomeric composite polylactic acid through a solution blending method, the hollow isomeric composite polylactic acid is subjected to nano-micronization treatment under a vacuum state, drying treatment is carried out, O-carboxymethyl chitosan, edible toner and edible toner powder are added or gel is added to generate a gel substance, and when the product is used, the particles impact dirt in movement by utilizing friction motion, so that the dirt and dental plaque are removed at an accelerated speed, and thus, a dyeing factor is attached to the surface of teeth, the effect of dyeing the teeth is achieved, and the product is green, environment-friendly, non-toxic and non-irritant and has good use experience.
The toner titanium dioxide is prepared by mixing 15-25% of nano titanium dioxide, 0.5-1.0% of protease, 3-5.5% of polyvinyl alcohol, 1.5-2.5% of lanolin, 1.0-2.5% of butyl propionate, 3.5-5.0% of glycerol, 1-2% of sodium alginate, 3-5% of sodium polyacrylate, 10.3-0.6% of vitamin B, 0.1-0.4% of tocopherol, 0.1-0.5% of panthenol, 1-2% of sodium benzoate and the balance of water, and the biodegradable cleaning agent with fruit flavor can be obtained by mixing strawberry, durian, lemon, mango, banana, juicy peach, apple, bergamot pear and candied date, so that the biodegradable cleaning agent with multi-vitamin supplement is provided, also relates to a plurality of natural peptidic compounds, which can be attached to the surface of the tooth for a long time, improve the soil protective film of the tooth, have the stronger purpose of blocking acid and alkali, and improve the natural smoothness of the tooth.
Mixing isomeric composite polylactic acid (4-6 components), O-carboxymethyl chitosan (2-3 components), hydrogen peroxide solution (2-3 components) and edible flavoring agent to form the cleaning agent, and making into toothpaste product.
Adding a brightening agent and an anti-wear agent into the isomeric composite polylactic acid.
In a first embodiment of the present invention, a first,
so that O-CMCS nano-particles with the particle size mainly distributed at 370-710 nm are generated when the concentration of the O-carboxymethyl chitosan (O-CMCS) solution is 1.0 mg/mL.
In a second embodiment of the present invention, a second,
the toner titanium dioxide is prepared by mixing 15-25% of nano titanium dioxide, 0.5-1.0% of protease, 3-5.5% of polyvinyl alcohol, 1.5-2.5% of lanolin, 1.0-2.5% of butyl propionate, 3.5-5.0% of glycerol, 1-2% of sodium alginate, 3-5% of sodium polyacrylate, 10.3-0.6% of vitamin B, 0.1-0.4% of tocopherol, 0.1-0.5% of panthenol, 1-2% of sodium benzoate and the balance of water, and the biodegradable cleaning agent with fruit flavor can be obtained by mixing strawberry, durian, lemon, mango, banana, juicy peach, apple, bergamot pear and candied date, so that the biodegradable cleaning agent with multi-vitamin supplement is provided, also relates to a plurality of natural peptidic compounds, which can be attached to the surface of the tooth for a long time, improve the soil protective film of the tooth, have the stronger purpose of blocking acid and alkali, and improve the natural smoothness of the tooth.
In the third embodiment,
| categories | Content of the components |
| Isomeric composite polylactic acid | 4 |
| O-carboxymethyl chitosan | 2 |
| Hydrogen peroxide solution | 3 |
| Edible flavoring agent | 1 |
The cleaning agent is prepared by mixing the isomeric composite polylactic acid (4 components), the O-carboxymethyl chitosan (2 components), the hydrogen peroxide solution (3 components) and the edible flavoring agent (1 component) in the table to prepare a toothpaste product;
the cleaning agent is prepared by mixing the isomeric composite polylactic acid (5 components), O-carboxymethyl chitosan (2 components), hydrogen peroxide solution (2 components) and edible flavoring agent (1 component) in the table to form the toothpaste product.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. A biodegradable cleaning agent for teeth, characterized by comprising the following preparation steps:
firstly, obtaining hollow isomeric composite polylactic acid particles by using a foaming technology, and drying the particles in a vacuum state;
secondly, completely dissolving the dried particles of the hollow isomeric composite polylactic acid in absolute ethyl alcohol edible toner titanium dioxide and an edible flavoring agent;
and step three, adding turmeric natural yellow pigment and purple red pigment.
And step four, finally, adding the mixed materials in the step two into a melting mixer, and melting and blending for 2-10 min at the temperature of 110-180 ℃ and the rotating speed of 20-120 rpm.
2. The biodegradable cleaning agent for teeth according to claim 1, wherein the foaming technology is used to obtain hollow heterogeneous composite polylactic acid, the hollow heterogeneous composite polylactic acid is subjected to nano-micronization, O-carboxymethyl chitosan, edible toner and edible toner are added to obtain powder or gel-forming gel-like substances are added, and the concentration of the O-carboxymethyl chitosan (O-CMCS) solution is 0.4-1.6 mg/mL, so that O-CMCS nanoparticles with the particle size mainly distributed in 370-710 nm are generated when the concentration of the O-carboxymethyl chitosan (O-CMCS) solution is 1.0 mg/mL.
3. The biodegradable cleaning agent for teeth according to claim 1, wherein said toner titanium dioxide is a mixture of biodegradable cleaning agents having fruit flavor type obtained from strawberry, durian, lemon, mango, banana, juicy peach, apple, bergamot pear, and candied date.
4. The biodegradable cleanser for teeth of claim 1, wherein said isomeric complex polylactic acid (4-6 components), O-carboxymethyl chitosan (2-3 components), hydrogen peroxide solution (2-3 components) and edible flavoring agent are mixed to form a cleanser, and then the cleanser is prepared into a toothpaste product.
5. The biodegradable cleaning agent for teeth as claimed in claim 1, wherein said heterogeneous composite polylactic acid is added with a brightening agent and an anti-wear agent.
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