CN113970943A - Water circulation system for pharmacy and application method - Google Patents
Water circulation system for pharmacy and application method Download PDFInfo
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- CN113970943A CN113970943A CN202111056580.2A CN202111056580A CN113970943A CN 113970943 A CN113970943 A CN 113970943A CN 202111056580 A CN202111056580 A CN 202111056580A CN 113970943 A CN113970943 A CN 113970943A
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D27/00—Simultaneous control of variables covered by two or more of main groups G05D1/00 - G05D25/00
- G05D27/02—Simultaneous control of variables covered by two or more of main groups G05D1/00 - G05D25/00 characterised by the use of electric means
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/008—Control or steering systems not provided for elsewhere in subclass C02F
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2103/00—Nature of the water, waste water, sewage or sludge to be treated
- C02F2103/02—Non-contaminated water, e.g. for industrial water supply
- C02F2103/026—Treating water for medical or cosmetic purposes
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2209/00—Controlling or monitoring parameters in water treatment
- C02F2209/02—Temperature
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2209/00—Controlling or monitoring parameters in water treatment
- C02F2209/03—Pressure
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2209/00—Controlling or monitoring parameters in water treatment
- C02F2209/20—Total organic carbon [TOC]
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2209/00—Controlling or monitoring parameters in water treatment
- C02F2209/40—Liquid flow rate
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
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Abstract
The invention provides a water circulation system for pharmacy and an application method, comprising the following steps: the water storage tank, the heat exchanger and the circulating pump are sequentially connected in a loop manner; the water return port and the water outlet of the water storage tank are respectively provided with an electromagnetic valve, and the water storage tank is also respectively connected with a liquid inlet pipeline and an air filter through the electromagnetic valves; a water draining pipeline is arranged on a connecting pipeline between a water return port of the water storage tank and the heat exchanger, and an electromagnetic valve is arranged on the water draining pipeline; the water storage tank, the heat exchanger and the circulating pump are provided with a sensor group and a plurality of water consumption points on the circulating pipelines, the plurality of water consumption points are branches connected with the circulating pipelines, and the plurality of branches are provided with electromagnetic valves; the sensor group and all the electromagnetic valves are connected with a controller; the controller is also connected with the circulating pump and controls the electromagnetic valve and the circulating pump on the loop-back pipeline according to the data collected by the sensor group. The invention reduces the risk of pollution of the water consumption point to the circulating system and improves the safety of the medicine while maintaining the system not to be polluted.
Description
Technical Field
The invention belongs to the technical field of pharmaceutical water, and particularly relates to a pharmaceutical water circulating system and an application method thereof.
Background
The safety of the medicine is a big concern about the health of the people, a large amount of purified water and injection water are used in the production process of the medicine, and the quality of the water directly determines the quality of the medicine, so that the preparation, storage and distribution of the purified water and the injection water are required to prevent the breeding and pollution of microorganisms.
The preparation process and the storage process of the water for pharmacy have perfect technology to prevent pollution, the design process of the present distribution system (namely a circulating system) focuses on the following aspects, 1, a circulating water supply mode is adopted, the residence time of water in a pipeline is reduced mainly on the basis of ensuring a certain flow rate (more than 0.9m/s) in the water pipeline and reducing dead water areas such as a blind pipe section and the like as far as possible, the design basis that running water does not decay is adopted, and the continuously circulating water system is utilized to easily maintain the control level of microorganisms in a normal water supply system to prevent the pollution of the microorganisms; 2, the injection water system adopts heat preservation circulation at the temperature of more than 70 ℃ to reduce the breeding of microorganisms; 3 the circulating system adopts the slope design, can exhaust the water in the pipeline when stopping circulating, has reduced the pollution of microorganism. And 4, controlling microorganisms in a regular disinfection mode.
The above solutions in the design of the circulation system only consider the system as an independent system, in the process of producing the medicine, the water system is a part of the system and is not independent, the circulation distribution of the water system is used for supplying each water using point, the invention aims to reduce the pollution risk of the water using point to the water system and quickly and effectively treat the water after pollution.
Disclosure of Invention
In view of the above-mentioned deficiencies of the prior art, the present invention provides a water circulation system for pharmaceutical use and an application method thereof, so as to solve the above-mentioned technical problems.
The invention provides a water circulation system for pharmacy, comprising: the water storage tank, the heat exchanger and the circulating pump are sequentially connected in a loop manner; the water return port and the water outlet of the water storage tank are both provided with electromagnetic valves, and the water storage tank is also respectively connected with a liquid inlet pipeline and an air filter through the electromagnetic valves; a water drainage pipeline is arranged on a connecting pipeline between a water return port of the water storage tank and the heat exchanger, and an electromagnetic valve is arranged on the water drainage pipeline; a sensor group and a plurality of water consumption points are arranged on the circulating pipelines of the water storage tank, the heat exchanger and the circulating pump, the plurality of water consumption points are branches connected with the circulating pipelines, and the plurality of branches are provided with electromagnetic valves; the sensor group and all the electromagnetic valves are connected with a controller; the controller is also connected with a circulating pump, and the controller controls the electromagnetic valve and the circulating pump on the loop-back pipeline according to the data collected by the sensor group.
Furthermore, a first electromagnetic valve is arranged at a water return port of the water storage tank, a second electromagnetic valve is arranged on a communication pipeline between the water storage tank and the liquid inlet pipeline, and a third electromagnetic valve is arranged on a communication pipeline between the water storage tank and the air filter; the water return port, the communication position with the liquid inlet pipeline and the communication position with the air filter are all arranged at the top of the water storage tank.
Further, the air filter comprises an air accommodating chamber, one port of the air accommodating chamber is communicated with the water storage tank through a third electromagnetic valve, a pipeline between the one port of the air accommodating chamber and the third electromagnetic valve is also communicated with a condensed water outlet branch, and a fourth electromagnetic valve is arranged on the condensed water outlet branch; the other port of the air filter is communicated with the steam inlet branch and the valve branch, a fifth electromagnetic valve is arranged on the valve branch, and a sixth electromagnetic valve is arranged on the steam inlet branch.
Furthermore, a pipeline between the first electromagnetic valve and the heat exchanger is communicated with a drainage pipeline, and a seventh electromagnetic valve is arranged on the drainage pipeline; the heat exchange inlet of the heat exchanger is respectively communicated with the steam pipeline and the cooling water inlet pipe, and the heat exchange outlet of the heat exchanger is respectively communicated with the condensation water pipeline and the cooling water outlet pipe; the steam pipeline is provided with an eighth electromagnetic valve, the cooling water inlet pipe is provided with a ninth electromagnetic valve, the condensed water pipeline is sequentially provided with a tenth electromagnetic valve and a drain valve, and the cooling water outlet pipe is provided with an eleventh electromagnetic valve.
Furthermore, the heat exchanger is communicated with the circulating pump, a plurality of water using points are arranged between the heat exchanger and a communication pipeline of the circulating pump, each water using point is a water outlet branch, and each water outlet branch is provided with a water using electromagnetic valve; the circulating pump is communicated with a water outlet at the bottom of the water storage tank, and a twelfth electromagnetic valve is arranged at the water outlet of the water storage tank.
Furthermore, the sensor group comprises a pressure sensor, a plurality of temperature sensors, a flow meter, a flow velocity meter, an online conductivity meter and a TOC detector.
Further, the pressure sensor detects the pressure value of the pipeline between the circulating pump and the pipeline area connected with the water consumption point; a first temperature sensor is arranged on a pipeline between the pipeline area connected with the water consumption point and the heat exchanger; and a second temperature sensor, a flow meter, a flow velocity meter and an online conductivity meter are arranged on a pipeline between the heat exchanger and the water storage tank.
Furthermore, if the water storage tank stores injection water, a TOC detector is also arranged on a pipeline between the heat exchanger and the water storage tank.
The invention also provides a pharmaceutical water circulation system application, which comprises: the controller controls the circulating pump to start according to a set frequency, and receives parameters collected by the sensor group after the circulating pump is started, wherein the parameters comprise flow rate, pressure value, temperature and conductivity;
the controller adjusts the working frequency of the circulating pump according to the flow rate so as to keep the flow rate within a set flow rate range, and at the moment, the controller grants the valve control authority of the water using electromagnetic valve; if the duration time of the flow rate lower than the lower limit of the set flow rate range exceeds the set regulation period, withdrawing the valve control authority of all the water using electromagnetic valves, and opening a second electromagnetic valve to make the water storage tank supplemented with water; converting the pressure value acquired by the pressure sensor into the liquid level of the water storage tank, if the liquid level of the water storage tank is lower than a set liquid level lower limit threshold, withdrawing the valve control authority of all water using electromagnetic valves, and opening a second electromagnetic valve to make the water storage tank supplement water; if the liquid level of the water storage tank exceeds a set upper liquid level threshold, closing the first electromagnetic valve, and opening a seventh electromagnetic valve on the drainage pipeline to drain water outwards; when water is supplemented to the water storage tank or water is drained outwards, a third electromagnetic valve, a fourth electromagnetic valve, a fifth electromagnetic valve and a sixth electromagnetic valve of the air filter are synchronously opened, and the air pressure of the water storage tank is kept at the atmospheric pressure; if the temperature exceeds the set temperature threshold, recovering the valve control authority of each water electromagnetic valve, and controlling a ninth electromagnetic valve of a cooling water inlet pipe and an eleventh electromagnetic valve of a cooling water outlet pipe of the heat exchanger to cool the circulating water; if the conductivity exceeds the set conductivity threshold, recovering the valve control authority of each water solenoid valve, closing the first solenoid valve, opening the twelfth solenoid valve and the seventh solenoid valve, and after the specified time of flushing, if the conductivity still exceeds the set conductivity threshold, generating alarm information; timing the working time of the circulating pump, if the working time reaches a set actual threshold value, recovering the valve control authority of each water-using electromagnetic valve, opening an eighth electromagnetic valve, a tenth electromagnetic valve and a drain valve of the heat exchanger to heat circulating water, enabling the first electromagnetic valve and the twelfth electromagnetic valve to be in an open state at the moment, opening all the electromagnetic valves of the air filter, closing a second electromagnetic valve and a seventh electromagnetic valve, starting timing after the temperature reaches a set disinfection temperature threshold value, closing the eighth electromagnetic valve, the tenth electromagnetic valve and the drain valve of the heat exchanger after the timing time reaches the set disinfection time, opening a ninth electromagnetic valve and an eleventh electromagnetic valve of the heat exchanger, and granting the valve control authority of each water-using electromagnetic valve after the temperature does not exceed the temperature threshold value.
The pharmaceutical water circulating system and the application method have the advantages that circulating water in the circulating water system is monitored, and once abnormality is found, the valve control authority of the water using electromagnetic valve is recovered, so that the risk of pollution of the circulating system by water using points is reduced while the system is maintained not to be polluted, and the safety of medicines is improved.
In addition, the invention has reliable design principle, simple structure and very wide application prospect.
Drawings
In order to more clearly illustrate the embodiments or technical solutions in the prior art of the present invention, the drawings used in the description of the embodiments or prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained based on these drawings without creative efforts.
FIG. 1 is a schematic diagram of a pharmaceutical water circulation system for purifying water according to one embodiment of the present application.
FIG. 2 is a flow chart of a method of using the pharmaceutical water circulation system for purifying water according to one embodiment of the present application.
FIG. 3 is a flow chart of a method for disinfecting a pharmaceutical water circulation system of purified water according to one embodiment of the present application.
Fig. 4 is a schematic structural view of an injection water circulation system according to an embodiment of the present application.
Fig. 5 is a flow chart of an application method of the water circulation system for injection according to an embodiment of the present application.
Fig. 6 is a flow chart of a method for disinfecting an injection water circulation system according to an embodiment of the present application.
Wherein, 1, a water storage tank; 2. a heat exchanger; 3. a circulation pump; 4. a first solenoid valve; 5. a second solenoid valve; 6. a third electromagnetic valve; 7. an air accommodating chamber; 8. a fourth solenoid valve; 9. a fifth solenoid valve; 10. a sixth electromagnetic valve; 11. a seventh electromagnetic valve; 12. an eighth solenoid valve; 13. a ninth electromagnetic valve; 14. a tenth solenoid valve; 15. an eleventh electromagnetic valve; 16. a twelfth electromagnetic valve; 17. a drain valve; 18. a water solenoid valve; 19. a pressure sensor; 20. a first temperature sensor; 21. a second temperature sensor; 22. a flow meter; 23. a flow rate meter; 24. an on-line conductivity meter; 25. TOC detector.
Detailed Description
In order to make those skilled in the art better understand the technical solution of the present invention, the technical solution in the embodiment of the present invention will be clearly and completely described below with reference to the drawings in the embodiment of the present invention, and it is obvious that the described embodiment is only a part of the embodiment of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.
In the description of the present invention, it is to be understood that the terms "first", "second", and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
The present invention will be described in detail below with reference to the embodiments with reference to the attached drawings.
Example 1
This embodiment provides a water circulation system for pharmaceutical use, which mainly treats purified water, as shown in fig. 1, and comprises the following structures:
the water storage tank 1, the heat exchanger 2 and the circulating pump 3 are sequentially connected in a loop manner; a sensor group and a plurality of water consumption points are arranged on the circulating pipelines of the water storage tank 1, the heat exchanger 2 and the circulating pump 3, the plurality of water consumption points are branches connected with the circulating pipelines, and the plurality of branches are provided with electromagnetic valves; the sensor group and all the electromagnetic valves are connected with a controller; the controller is also connected with a circulating pump 3, and the controller controls the electromagnetic valve on the loop-back pipeline and the circulating pump 3 according to data collected by the sensor group.
A first electromagnetic valve 4 is arranged at a water return port of the water storage tank 1, a second electromagnetic valve 5 is arranged on a communication pipeline between the water storage tank 1 and the liquid inlet pipeline, and a third electromagnetic valve 6 is arranged on a communication pipeline between the water storage tank 1 and the air filter; the water return port, the communication position with the liquid inlet pipeline and the communication position with the air filter are arranged at the top of the water storage tank 1. The air filter comprises an air accommodating chamber 7, one port of the air accommodating chamber 7 is communicated with the water storage tank 1 through a third electromagnetic valve 6, a pipeline between one port of the air accommodating chamber 7 and the third electromagnetic valve 6 is also communicated with a condensed water outlet branch, and a fourth electromagnetic valve 8 is arranged on the condensed water outlet branch; the other port of the air filter is communicated with a steam inlet branch and a valve branch, a fifth electromagnetic valve 9 is arranged on the valve branch, and a sixth electromagnetic valve 10 is arranged on the steam inlet branch. A pipeline between the first electromagnetic valve 4 and the heat exchanger 2 is communicated with a drainage pipeline, and a seventh electromagnetic valve 11 is arranged on the drainage pipeline; a heat exchange inlet of the heat exchanger 2 is respectively communicated with a steam pipeline and a cooling water inlet pipe, and a heat exchange outlet of the heat exchanger 2 is respectively communicated with a condensation water pipeline and a cooling water outlet pipe; an eighth electromagnetic valve 12 is arranged on the steam pipeline, a ninth electromagnetic valve 13 is arranged on the cooling water inlet pipe, a tenth electromagnetic valve 14 and a drain valve 17 are sequentially arranged on the condensed water pipeline, and an eleventh electromagnetic valve 15 is arranged on the cooling water outlet pipe. The heat exchanger 2 is communicated with the circulating pump 3, a plurality of water using points are arranged between the heat exchanger 2 and a communication pipeline of the circulating pump 3, each water using point is a water outlet branch, and each water outlet branch is provided with a water using electromagnetic valve 18; the circulating pump 3 is communicated with a water outlet at the bottom of the water storage tank 1, and a twelfth electromagnetic valve 16 is arranged at the water outlet of the water storage tank 1.
The sensor group comprises a pressure sensor 19, a plurality of temperature sensors, a flow meter 22, a flow rate meter 23 and an online conductivity meter 24. The pressure sensor 19 detects the pressure value of the pipeline between the circulating pump 3 and the pipeline region connected with the water consumption point; a first temperature sensor 20 is arranged on a pipeline between the pipeline area connected with the water consumption point and the heat exchanger 2; a second temperature sensor 21, a flow meter 22, a flow rate meter 23 and an online conductivity meter 24 are arranged on a pipeline between the heat exchanger 2 and the water storage tank 1.
With respect to the above-described circulation system for treating purified water, the present embodiment provides the following application methods: the controller controls the circulating pump 3 to start according to a set frequency, and receives parameters collected by the sensor group after the circulating pump 3 starts, wherein the parameters comprise flow rate, pressure value, temperature and conductivity; the controller adjusts the working frequency of the circulating pump 3 according to the flow rate so as to keep the flow rate within a set flow rate range, and at the moment, the controller grants the valve control authority of the water using electromagnetic valve 18; if the duration time of the flow rate lower than the lower limit of the set flow rate range exceeds the set regulation period, withdrawing the valve control authority of all the water using electromagnetic valves 18, and opening the second electromagnetic valve 5 to make the water storage tank 1 supplemented with water; converting the pressure value acquired by the pressure sensor 19 into the liquid level of the water storage tank 1, if the liquid level of the water storage tank 1 is lower than a set liquid level lower limit threshold, withdrawing the valve control permission of all the water using electromagnetic valves 18, and opening the second electromagnetic valve 5 to make the water storage tank 1 supplement water; if the liquid level of the water storage tank 1 exceeds a set upper liquid level threshold, closing the first electromagnetic valve 4, and opening a seventh electromagnetic valve 11 on a drainage pipeline to drain water outwards; when water is supplemented to the water storage tank 1 or water is drained outwards, a third electromagnetic valve 6, a fourth electromagnetic valve 8, a fifth electromagnetic valve 9 and a sixth electromagnetic valve 10 of the air filter are synchronously opened, and the air pressure of the water storage tank 1 is kept at the atmospheric pressure; if the temperature exceeds the set temperature threshold, the valve control authority of each water-using electromagnetic valve 18 is recovered, and a ninth electromagnetic valve 13 of a cooling water inlet pipe and an eleventh electromagnetic valve 15 of a cooling water outlet pipe of the heat exchanger 2 are controlled to cool the circulating water; if the conductivity exceeds the set conductive threshold, the valve control authority of each water solenoid valve 18 is recovered, the first solenoid valve 4 is closed, the twelfth solenoid valve 16 and the seventh solenoid valve 11 are opened, and after the specified period of flushing, if the conductivity still exceeds the set conductive threshold, alarm information is generated.
Referring to fig. 2, the specific method is as follows:
equipment parameters:
a purified water storage tank (volume: 20000L), a circulating pump 3 (flow: 20000L/h, lift 50m), a pressure sensor 19 (range: 0-6 bar), a temperature sensor I (range: 0-150 ℃), a heat exchanger 2, a second temperature sensor 21 (range: 0-150 ℃), a flow meter 22 (range: 0-10L/S), a flow rate meter 23 (0-2 m/S), and an online conductivity meter 24 (0-50 uS/cm);
controlling parameters:
the initial frequency V0(25Hz), the liquid return flow velocity Vt (1.0m/S), the liquid supplementing liquid level H1(1000mm), the liquid supplementing stopping liquid level H2(2000mm), the liquid supply stopping liquid level H3(500mm), the liquid supply level H4(800mm), the purified water early warning temperature Tt (25 ℃), and the purified water early warning conductivity Ct (1.0uS/cm) of the circulating pump 3.
The first step is as follows: condition confirmation before purified water circulation is started: 1) the air supply pressure of the valve is 0.6-0.8MPa, and the alarm prompt is given when the air supply pressure is lower than the pressure; 2) and (4) recovering the valve control authority of the water consumption point, automatically closing all valves of the water consumption point, displaying the state of the water consumption electromagnetic valve 18 as a forbidden state, and opening the valve on the circulating pipeline.
And secondly, starting the circulating pump 3 at the initial circulating pump 3 frequency of 25Hz according to the set V0 for 1min, automatically opening the online temperature and conductivity, and automatically controlling the circulating pump 3 frequency according to the Vt return flow rate set value of 1.0 m/s.
And thirdly, after all parameters of the system, such as temperature, conductivity and liquid level, are qualified, the control right of the water using electromagnetic valve 18 is released, and the water using electromagnetic valve 18 is displayed as a usable state.
Fourthly, all detectors are always in a monitoring state in the circulation process of the system.
When part of water is used, the flow rate of the return liquid is reduced, and when the flow rate of the return liquid is lower than the set flow rate of the return liquid, the frequency of the circulating pump 3 is controlled to be increased, and the flow rate is maintained at the set value of 1.0 m/s.
The water storage tank 1 is continuously used along with water consumption points, the liquid level L is continuously reduced, when the liquid level is reduced to 1000mm, the purified water making device is automatically started to supplement purified water, when the liquid level reaches 2000mm, the purified water making device is closed to stop supplementing purified water, and the steps are repeated in this way, so that a better liquid level is maintained. When the water consumption points 1, 2 and 3 are all used, the liquid level L is continuously reduced due to larger usage amount or untimely purified water supplement, the system recovers the valve control right of each water consumption point after the liquid level L is reduced to 500mm, the water consumption electromagnetic valve 18 is closed to ensure the normal circulation of the circulating system, prevent microorganisms from breeding due to the fact that the liquid level L is too low and stops circulating, and the water consumption points are allowed to be used when the liquid level is more than 800 mm; in the circulation process of the water consumption point, the temperature of the purified water T can be continuously increased, once the temperature is higher than 25 ℃, the proliferation speed of microorganisms can be obviously accelerated, and in order to prevent the phenomenon, when the temperature of the purified water is higher than 25 ℃, the ninth electromagnetic valve 13 and the eleventh electromagnetic valve 15 of the heat exchanger 2 are automatically opened to circulate cooling water and reduce the temperature to below 25 ℃.
When the circulating pump 3 is abnormal, the flow rate of the return liquid is rapidly reduced, the outlet pressure of the pump port is rapidly reduced, the system recovers the valve control power of each water consumption point at the moment, the water consumption electromagnetic valve 18 is closed, the state of the water consumption electromagnetic valve 18 is displayed as a forbidden state, and the situation that medicines, air or other solutions of the water consumption points flow back to the purified water circulating distribution system to pollute the water system due to the fact that the valves are opened by the water consumption points is prevented.
When the water consumption point or the heat exchanger 2 has leakage and the like and pollution occurs, the on-line conductivity detection conductivity of the liquid return pipeline is more than 1.0uS/cm, at the moment, the system withdraws the valve control power of each water consumption point, the water consumption electromagnetic valve 18 is closed, the state of the water consumption electromagnetic valve 18 is displayed as a forbidden state, meanwhile, the system automatically opens the seventh electromagnetic valve 11, closes the first electromagnetic valve 4 and flushes the circulating pipeline, after unqualified water is discharged, flushing is continued until the on-line conductivity is qualified and maintained for 30s, the control power of the water consumption electromagnetic valve 18 is released, the water consumption electromagnetic valve 18 is displayed as an available state, simultaneously closes the seventh electromagnetic valve 11 and opens the first electromagnetic valve 4, and when the conductivity of the system is still over standard after flushing for 1min, the system stops and alarms, and waits for manual pollution confirmation.
Referring to fig. 3, the system is sterilized. When the system runs for a certain time, the system withdraws the valve control power of each water consumption point, the water consumption electromagnetic valve 18 is closed, the state of the water consumption electromagnetic valve 18 is displayed as a forbidden state, the eighth electromagnetic valve 12, the tenth electromagnetic valve 14 and the drain valve 17 of the heat exchanger 2 are opened to heat the circulating water, when the temperature sensors in the water storage tank 1, in front of the heat exchanger 2 and behind the heat exchanger 2 reach 80 ℃, the timing is started, after 1h, the temperature is reduced to below 25 ℃, the control power of the water consumption electromagnetic valve 18 is released by the system, and the water consumption electromagnetic valve 18 is displayed as an available state.
Example 2
Referring to fig. 4, the present embodiment provides a water circulation system for injection, including the following structures:
the water storage tank 1, the heat exchanger 2 and the circulating pump 3 are sequentially connected in a loop manner; a sensor group and a plurality of water consumption points are arranged on the circulating pipelines of the water storage tank 1, the heat exchanger 2 and the circulating pump 3, the plurality of water consumption points are branches connected with the circulating pipelines, and the plurality of branches are provided with electromagnetic valves; the sensor group and all the electromagnetic valves are connected with a controller; the controller is also connected with a circulating pump 3, and the controller controls the electromagnetic valve on the loop-back pipeline and the circulating pump 3 according to data collected by the sensor group.
A first electromagnetic valve 4 is arranged at a water return port of the water storage tank 1, a second electromagnetic valve 5 is arranged on a communication pipeline between the water storage tank 1 and the liquid inlet pipeline, and a third electromagnetic valve 6 is arranged on a communication pipeline between the water storage tank 1 and the air filter; the water return port, the communication position with the liquid inlet pipeline and the communication position with the air filter are arranged at the top of the water storage tank 1. The air filter comprises an air accommodating chamber 7, one port of the air accommodating chamber 7 is communicated with the water storage tank 1 through a third electromagnetic valve 6, a pipeline between one port of the air accommodating chamber 7 and the third electromagnetic valve 6 is also communicated with a condensed water outlet branch, and a fourth electromagnetic valve 8 is arranged on the condensed water outlet branch; the other port of the air filter is communicated with a steam inlet branch and a valve branch, a fifth electromagnetic valve 9 is arranged on the valve branch, and a sixth electromagnetic valve 10 is arranged on the steam inlet branch. A pipeline between the first electromagnetic valve 4 and the heat exchanger 2 is communicated with a drainage pipeline, and a seventh electromagnetic valve 11 is arranged on the drainage pipeline; a heat exchange inlet of the heat exchanger 2 is respectively communicated with a steam pipeline and a cooling water inlet pipe, and a heat exchange outlet of the heat exchanger 2 is respectively communicated with a condensation water pipeline and a cooling water outlet pipe; an eighth electromagnetic valve 12 is arranged on the steam pipeline, a ninth electromagnetic valve 13 is arranged on the cooling water inlet pipe, a tenth electromagnetic valve 14 and a drain valve 17 are sequentially arranged on the condensed water pipeline, and an eleventh electromagnetic valve 15 is arranged on the cooling water outlet pipe. The heat exchanger 2 is communicated with the circulating pump 3, a plurality of water using points are arranged between the heat exchanger 2 and a communication pipeline of the circulating pump 3, each water using point is a water outlet branch, and each water outlet branch is provided with a water using electromagnetic valve 18; the circulating pump 3 is communicated with a water outlet at the bottom of the water storage tank 1, and a twelfth electromagnetic valve 16 is arranged at the water outlet of the water storage tank 1.
The sensor group comprises a pressure sensor 19, a plurality of temperature sensors, a flow meter 22, a flow rate meter 23 and an online conductivity meter 24. The pressure sensor 19 detects the pressure value of the pipeline between the circulating pump 3 and the pipeline region connected with the water consumption point; a first temperature sensor 20 is arranged on a pipeline between the pipeline area connected with the water consumption point and the heat exchanger 2; a second temperature sensor 21, a flow meter 22, a flow rate meter 23, an online conductivity meter 24 and a TOC detector 25 are arranged on a pipeline between the heat exchanger 2 and the water storage tank 1.
In view of the above-mentioned water circulation system for injection, the present embodiment provides an application method, as shown in fig. 5, including:
the respective equipment and control parameters are as follows:
equipment parameters:
a water storage tank 1 (volume: 30000L), a circulating pump 3 (flow rate: 20000L/h, lift 50m), a pressure sensor 19 (measuring range: 0-6 bar), a first temperature sensor 20 (measuring range: 0-150 ℃), a heat exchanger 2, a second temperature sensor 21 (measuring range: 0-150 ℃), a flow meter 22 (measuring range: 0-10L/S), a flow rate meter 23 (0-2 m/S), an online TOC detector 25 (0.1-999.99), and an online conductivity meter 24 (0-50 uS/cm);
controlling parameters:
the initial frequency V0(25Hz), the liquid return flow rate Vt (1.0m/S), the liquid supplementing liquid level H1(1000mm), the liquid supplementing stopping liquid level H2(2000mm), the liquid supply stopping liquid level H3(500mm), the liquid supply level H4(800mm), the early warning temperature Tt (70 ℃) of the injection water, the early warning conductivity Ct (1.0uS/cm) of the purified water and the qualified value C1(500ppb) of the TOC of the circulating pump 3.
The first step is as follows: and (3) confirming conditions before starting the water circulation for injection: 1) the air supply pressure of the valve is 0.6-0.8MPa, and the alarm prompt is given when the air supply pressure is lower than the pressure; 2) and (3) recovering the valve control authority of the water consumption point, automatically closing all valves of the water consumption point, displaying the state of the water consumption electromagnetic valve 18 as a forbidden state, and opening the first electromagnetic valve 4 and the twelfth electromagnetic valve 16 on the circulating pipeline.
And secondly, starting the circulating pump 3 at the initial circulating pump 3 frequency of 25Hz according to the set V0 for 1min, automatically opening the online temperature, conductivity and TOC, and automatically controlling the circulating pump 3 frequency according to the Vt return flow rate set value of 1.0 m/s.
And thirdly, after all parameters of the water system, such as temperature, conductivity, TOC and liquid level are qualified, releasing the control right of the water using electromagnetic valve 18, and displaying the available state of the water using electromagnetic valve 18.
Fourthly, all detectors are always in a monitoring state in the circulation process of the system.
When part of water is used, the flow rate of the return liquid is reduced, and when the flow rate of the return liquid is lower than the set flow rate of the return liquid, the frequency of the circulating pump 3 is automatically increased and is maintained at the set value of 1.0 m/s.
The injection water storage tank is continuously used along with the water consumption point, the liquid level L is continuously reduced, when the liquid level is reduced to 1000mm, the second electromagnetic valve 5 is automatically opened to replenish the injection water, when the liquid level reaches 2000mm, the second electromagnetic valve 5 is closed, and the steps are repeated in this way, so that a better liquid level is maintained. When the water consumption points 1, 2 and 3 are all used, the liquid level L is continuously reduced due to larger usage amount or untimely replenishment of injection water, the system recovers the valve control right of each water consumption point after the liquid level L is reduced to 500mm, the water consumption electromagnetic valve 18 is closed to ensure the normal circulation of the circulating system, prevent microorganisms from breeding due to the fact that the liquid level L is too low and stops circulation, and allow the water consumption points to be used when the liquid level is more than 800 mm; in the circulation process of the water consumption point, the temperature of the injection water T can be continuously increased and decreased, once the temperature is lower than 70 ℃, the microorganism proliferation speed can be obviously accelerated, and in order to prevent the phenomenon, when the temperature of the purified water is lower than 75 ℃, the steam inlet of the heat exchanger 2 and the drain valve 17 are automatically opened, and the temperature is increased to be higher than 75 ℃.
When the circulating pump 3 is abnormal, the V return flow rate is rapidly reduced, the outlet pressure of the pump is rapidly reduced, the system recovers the valve control power of each water consumption point at the moment, the water consumption electromagnetic valve 18 is closed, the state of the water consumption electromagnetic valve 18 is displayed as a forbidden state, and the problem that medicines, air or other solutions of the water consumption points flow back to the injection water circulating distribution system to pollute the water system due to the fact that the valves are opened by the water consumption points is avoided.
When the water consumption point or the heat exchanger 2 has leakage and the like and has pollution, the on-line conductivity detection conductivity of the liquid return pipeline is more than 1.0uS/cm or the TOC is more than 500ppb, at the moment, the system withdraws the valve control right of each water consumption point, the water consumption electromagnetic valve 18 is closed, the state of the water consumption electromagnetic valve 18 is displayed as a forbidden state, meanwhile, the system automatically opens the seventh electromagnetic valve 11 to close the first electromagnetic valve 4 and wash the circulating pipeline, after unqualified water is discharged, the system is continuously washed until the on-line conductivity is qualified and is maintained for 30s, the control right of the water consumption electromagnetic valve 18 is released, the water consumption electromagnetic valve 18 is displayed as an available state, meanwhile, the seventh electromagnetic valve 11 opens the first electromagnetic valve 4, and when the conductivity still exceeds the standard after the system is washed for 1min, the system is shut down and alarms to wait for manual confirmation of pollution.
Please refer to fig. 6 for a disinfection process of the injection water circulation system. When the system runs for a certain time, the system withdraws the valve control power of each water consumption point, the water consumption electromagnetic valve 18 is closed, the state of the water consumption electromagnetic valve 18 is displayed as a forbidden state, the eighth electromagnetic valve 12, the tenth electromagnetic valve 14 and the drain valve 17 of the heat exchanger 2 are opened, the temperature is raised, when the temperature sensors in the water storage tank 1, in front of the heat exchanger 2 and behind the heat exchanger 2 reach 121 ℃, the timing is started, after 1h is reached, the temperature is reduced to be below 75 ℃, the system releases the control power of the water consumption electromagnetic valve 18, and the water consumption electromagnetic valve 18 is displayed as an available state.
Although the present invention has been described in detail by referring to the drawings in connection with the preferred embodiments, the present invention is not limited thereto. Various equivalent modifications or substitutions can be made on the embodiments of the present invention by those skilled in the art without departing from the spirit and scope of the present invention, and these modifications or substitutions are within the scope of the present invention/any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (9)
1. A water circulation system for pharmacy, comprising: the water storage tank, the heat exchanger and the circulating pump are sequentially connected in a loop manner; the water return port and the water outlet of the water storage tank are both provided with electromagnetic valves, and the water storage tank is also respectively connected with a liquid inlet pipeline and an air filter through the electromagnetic valves; a water drainage pipeline is arranged on a connecting pipeline between a water return port of the water storage tank and the heat exchanger, and an electromagnetic valve is arranged on the water drainage pipeline; a sensor group and a plurality of water consumption points are arranged on the circulating pipelines of the water storage tank, the heat exchanger and the circulating pump, the plurality of water consumption points are branches connected with the circulating pipelines, and the plurality of branches are provided with electromagnetic valves; the sensor group and all the electromagnetic valves are connected with a controller; the controller is also connected with a circulating pump, and the controller controls the electromagnetic valve and the circulating pump on the loop-back pipeline according to the data collected by the sensor group.
2. The system according to claim 1, wherein a first electromagnetic valve is arranged at a water return port of the water storage tank, a second electromagnetic valve is arranged on a communication pipeline between the water storage tank and the liquid inlet pipeline, and a third electromagnetic valve is arranged on a communication pipeline between the water storage tank and the air filter; the water return port, the communication position with the liquid inlet pipeline and the communication position with the air filter are all arranged at the top of the water storage tank.
3. The system of claim 2, wherein the air filter comprises an air accommodating chamber, one port of the air accommodating chamber is communicated with the water storage tank through a third electromagnetic valve, a pipeline between the one port of the air accommodating chamber and the third electromagnetic valve is also communicated with a condensed water outlet branch, and a fourth electromagnetic valve is arranged on the condensed water outlet branch; the other port of the air filter is communicated with the steam inlet branch and the valve branch, a fifth electromagnetic valve is arranged on the valve branch, and a sixth electromagnetic valve is arranged on the steam inlet branch.
4. The system according to claim 3, characterized in that a pipeline between the first electromagnetic valve and the heat exchanger is communicated with a drainage pipeline, and a seventh electromagnetic valve is arranged on the drainage pipeline; the heat exchange inlet of the heat exchanger is respectively communicated with the steam pipeline and the cooling water inlet pipe, and the heat exchange outlet of the heat exchanger is respectively communicated with the condensation water pipeline and the cooling water outlet pipe; the steam pipeline is provided with an eighth electromagnetic valve, the cooling water inlet pipe is provided with a ninth electromagnetic valve, the condensed water pipeline is sequentially provided with a tenth electromagnetic valve and a drain valve, and the cooling water outlet pipe is provided with an eleventh electromagnetic valve.
5. The system according to claim 4, wherein the heat exchanger is communicated with the circulating pump, a plurality of water using points are arranged between the heat exchanger and a communication pipeline of the circulating pump, each water using point is a water outlet branch, and a water using electromagnetic valve is arranged on each water outlet branch; the circulating pump is communicated with a water outlet at the bottom of the water storage tank, and a twelfth electromagnetic valve is arranged at the water outlet of the water storage tank.
6. The system of claim 5, wherein the sensor group comprises at least one of a pressure sensor, a plurality of temperature sensors, a flow meter, a flow rate meter, an in-line conductivity meter, and a TOC meter.
7. The system of claim 6, wherein the pressure sensor detects a pressure value of the pipeline between the circulation pump and a pipeline region to which the water usage point is connected; a first temperature sensor is arranged on a pipeline between the pipeline area connected with the water consumption point and the heat exchanger; and a second temperature sensor, a flow meter, a flow velocity meter and an online conductivity meter are arranged on a pipeline between the heat exchanger and the water storage tank.
8. The system of claim 7, wherein if the water storage tank stores injection water, a TOC detector is further disposed on a pipeline between the heat exchanger and the water storage tank.
9. The application method of the water circulation system for pharmacy is applied to the system as claimed in claim 7, and is characterized in that the controller controls the circulating pump to start according to a set frequency and receives parameters collected by the sensor group after the circulating pump is started, wherein the parameters comprise flow rate, pressure value, temperature and conductivity;
the controller adjusts the working frequency of the circulating pump according to the flow rate so as to keep the flow rate within a set flow rate range, and at the moment, the controller grants the valve control authority of the water using electromagnetic valve; if the duration time of the flow rate lower than the lower limit of the set flow rate range exceeds the set regulation period, withdrawing the valve control authority of all the water using electromagnetic valves, and opening a second electromagnetic valve to make the water storage tank supplemented with water; converting the pressure value acquired by the pressure sensor into the liquid level of the water storage tank, if the liquid level of the water storage tank is lower than a set liquid level lower limit threshold, withdrawing the valve control authority of all water using electromagnetic valves, and opening a second electromagnetic valve to make the water storage tank supplement water; if the liquid level of the water storage tank exceeds a set upper liquid level threshold, closing the first electromagnetic valve, and opening a seventh electromagnetic valve on the drainage pipeline to drain water outwards; when water is supplemented to the water storage tank or water is drained outwards, a third electromagnetic valve, a fourth electromagnetic valve, a fifth electromagnetic valve and a sixth electromagnetic valve of the air filter are synchronously opened, and the air pressure of the water storage tank is kept at the atmospheric pressure; if the temperature exceeds the set temperature threshold, recovering the valve control authority of each water electromagnetic valve, and controlling a ninth electromagnetic valve of a cooling water inlet pipe and an eleventh electromagnetic valve of a cooling water outlet pipe of the heat exchanger to cool the circulating water; if the conductivity exceeds the set conductivity threshold, recovering the valve control authority of each water solenoid valve, closing the first solenoid valve, opening the twelfth solenoid valve and the seventh solenoid valve, and after the specified time of flushing, if the conductivity still exceeds the set conductivity threshold, generating alarm information; timing the working time of the circulating pump, if the working time reaches a set actual threshold value, recovering the valve control authority of each water-using electromagnetic valve, opening an eighth electromagnetic valve, a tenth electromagnetic valve and a drain valve of the heat exchanger to heat circulating water, enabling the first electromagnetic valve and the twelfth electromagnetic valve to be in an open state at the moment, opening all the electromagnetic valves of the air filter, closing a second electromagnetic valve and a seventh electromagnetic valve, starting timing after the temperature reaches a set disinfection temperature threshold value, closing the eighth electromagnetic valve, the tenth electromagnetic valve and the drain valve of the heat exchanger after the timing time reaches the set disinfection time, opening a ninth electromagnetic valve and an eleventh electromagnetic valve of the heat exchanger, and granting the valve control authority of each water-using electromagnetic valve after the temperature does not exceed the temperature threshold value.
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| CN202111056580.2A CN113970943B (en) | 2021-09-09 | 2021-09-09 | Pharmaceutical water circulation system and application method |
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| CN109821794A (en) * | 2019-03-08 | 2019-05-31 | 广西梧州制药（集团）股份有限公司 | Freeze dryer circulating cleaning equipment |
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| US20190274316A1 (en) * | 2018-03-12 | 2019-09-12 | Hunan University Of Science And Technology | Intelligent dehumidification device for hot air circulation baking system |
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| CN213629909U (en) * | 2020-10-30 | 2021-07-06 | 北京四环制药有限公司 | Pipeline water distribution system for multiple workshops |
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2021
- 2021-09-09 CN CN202111056580.2A patent/CN113970943B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20190274316A1 (en) * | 2018-03-12 | 2019-09-12 | Hunan University Of Science And Technology | Intelligent dehumidification device for hot air circulation baking system |
| CN209012796U (en) * | 2018-08-30 | 2019-06-21 | 上海臣邦医药科技股份有限公司 | A kind of water for pharmaceutical purposes cycle assignment system |
| CN209630659U (en) * | 2019-01-18 | 2019-11-15 | 浙江得恩德制药股份有限公司 | A kind of traditional Chinese medicine extraction concentrator water circulation cooling device |
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| CN213629909U (en) * | 2020-10-30 | 2021-07-06 | 北京四环制药有限公司 | Pipeline water distribution system for multiple workshops |
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