CN113939304A - M1病毒变异体及其应用 - Google Patents
M1病毒变异体及其应用 Download PDFInfo
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Abstract
提供一种M1病毒。进一步提供所述病毒的一系列应用，所述应用包括但不限于：病毒载体、抗肿瘤剂、药物组合物。所述病毒能够有效抑制多种肿瘤细胞的生长，同时具有肿瘤靶向性，对正常的细胞无毒性；可以经静脉注射的方式给药，具有操作上的便捷性。
Description
PCT国内申请，说明书已公开。
Claims (17)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2019104724397 | 2019-05-31 | ||
| CN201910472439 | 2019-05-31 | ||
| PCT/CN2020/093642 WO2020239118A1 (zh) | 2019-05-31 | 2020-05-31 | M1病毒变异体及其应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113939304A true CN113939304A (zh) | 2022-01-14 |
| CN113939304B CN113939304B (zh) | 2024-02-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202080040516.2A Active CN113939304B (zh) | 2019-05-31 | 2020-05-31 | M1病毒变异体及其应用 |
| CN202010486178.7A Pending CN112011519A (zh) | 2019-05-31 | 2020-06-01 | M1病毒变异体及其应用 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202010486178.7A Pending CN112011519A (zh) | 2019-05-31 | 2020-06-01 | M1病毒变异体及其应用 |
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| Country | Link |
|---|---|
| US (1) | US20220315903A1 (zh) |
| JP (2) | JP7457037B2 (zh) |
| CN (2) | CN113939304B (zh) |
| AU (1) | AU2020285291A1 (zh) |
| DE (1) | DE112020002641T9 (zh) |
| WO (1) | WO2020239118A1 (zh) |
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| CN118086395B (zh) * | 2024-04-25 | 2024-06-21 | 南京农业大学三亚研究院 | 一种盖塔病毒质粒载体、弱毒株及其制备方法和应用 |
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| US20170073377A1 (en) * | 2011-01-31 | 2017-03-16 | The Usa, As Represented By The Secretary, Department Of Health And Human Services | Virus-like particles and methods of use |
| CN107349226A (zh) * | 2014-08-26 | 2017-11-17 | 广州威溶特医药科技有限公司 | 甲病毒在制备抗肿瘤药物方面的应用 |
| CN108606982A (zh) * | 2016-08-18 | 2018-10-02 | 广州威溶特医药科技有限公司 | Vcp抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
| CN109207491A (zh) * | 2017-07-05 | 2019-01-15 | 中国科学院武汉物理与数学研究所 | 一种m1病毒全长感染性克隆及制备方法及其在制备m1病毒中的应用 |
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| BR112017019776B1 (pt) * | 2015-03-18 | 2020-07-28 | Omnicyte | proteínas de fusão que compreendem glicoproteínas de superfície de alfavírus modificadas e antígeno associado a tumor e métodos dos mesmos |
| CN105456302B (zh) * | 2015-12-23 | 2019-09-24 | 广州威溶特医药科技有限公司 | 大黄酚或其衍生物和溶瘤病毒在制备抗肿瘤药物的应用 |
| EP3478321A4 (en) * | 2016-06-30 | 2020-04-22 | Oncorus, Inc. | PSEUDOTYPIZED ONCOLYTIC VIRAL ADMINISTRATION OF THERAPEUTIC POLYPEPTIDES |
| CN106177955B (zh) * | 2016-08-18 | 2018-03-16 | 广州威溶特医药科技有限公司 | Bcl‑xL抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
| CN108686221B (zh) * | 2018-07-25 | 2022-02-22 | 广州威溶特医药科技有限公司 | 增效的抗肿瘤药物 |
-
2020
- 2020-05-31 AU AU2020285291A patent/AU2020285291A1/en active Pending
- 2020-05-31 JP JP2021571298A patent/JP7457037B2/ja active Active
- 2020-05-31 US US17/595,889 patent/US20220315903A1/en active Pending
- 2020-05-31 DE DE112020002641.8T patent/DE112020002641T9/de active Active
- 2020-05-31 WO PCT/CN2020/093642 patent/WO2020239118A1/zh active Application Filing
- 2020-05-31 CN CN202080040516.2A patent/CN113939304B/zh active Active
- 2020-06-01 CN CN202010486178.7A patent/CN112011519A/zh active Pending
-
2024
- 2024-03-14 JP JP2024039612A patent/JP2024086728A/ja active Pending
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| US20170073377A1 (en) * | 2011-01-31 | 2017-03-16 | The Usa, As Represented By The Secretary, Department Of Health And Human Services | Virus-like particles and methods of use |
| CN107349226A (zh) * | 2014-08-26 | 2017-11-17 | 广州威溶特医药科技有限公司 | 甲病毒在制备抗肿瘤药物方面的应用 |
| CN107456463A (zh) * | 2014-08-26 | 2017-12-12 | 广州威溶特医药科技有限公司 | 甲病毒在制备抗肿瘤药物方面的应用 |
| CN108606982A (zh) * | 2016-08-18 | 2018-10-02 | 广州威溶特医药科技有限公司 | Vcp抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
| CN109207491A (zh) * | 2017-07-05 | 2019-01-15 | 中国科学院武汉物理与数学研究所 | 一种m1病毒全长感染性克隆及制备方法及其在制备m1病毒中的应用 |
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2024086728A (ja) | 2024-06-28 |
| DE112020002641T5 (de) | 2022-08-04 |
| JP7457037B2 (ja) | 2024-03-27 |
| US20220315903A1 (en) | 2022-10-06 |
| CN113939304B (zh) | 2024-02-23 |
| AU2020285291A1 (en) | 2022-01-27 |
| WO2020239118A1 (zh) | 2020-12-03 |
| JP2022535010A (ja) | 2022-08-04 |
| DE112020002641T9 (de) | 2022-10-06 |
| CN112011519A (zh) | 2020-12-01 |
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