CN113907798A - Portable PTH detection device in operation process - Google Patents
Portable PTH detection device in operation process Download PDFInfo
- Publication number
- CN113907798A CN113907798A CN202111112417.3A CN202111112417A CN113907798A CN 113907798 A CN113907798 A CN 113907798A CN 202111112417 A CN202111112417 A CN 202111112417A CN 113907798 A CN113907798 A CN 113907798A
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- Prior art keywords
- portable
- pth
- negative pressure
- cavity
- electromagnetic valve
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- 238000001514 detection method Methods 0.000 title claims abstract description 43
- 238000000034 method Methods 0.000 title abstract description 11
- 238000012360 testing method Methods 0.000 claims abstract description 13
- 238000005070 sampling Methods 0.000 claims abstract description 10
- 238000001356 surgical procedure Methods 0.000 claims description 21
- 238000007865 diluting Methods 0.000 claims description 7
- 239000003085 diluting agent Substances 0.000 claims description 5
- 239000012895 dilution Substances 0.000 claims description 5
- 238000010790 dilution Methods 0.000 claims description 5
- 238000003780 insertion Methods 0.000 claims description 5
- 230000037431 insertion Effects 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 108090000445 Parathyroid hormone Proteins 0.000 description 22
- 102100036893 Parathyroid hormone Human genes 0.000 description 19
- 210000002990 parathyroid gland Anatomy 0.000 description 8
- 210000001519 tissue Anatomy 0.000 description 7
- 210000001685 thyroid gland Anatomy 0.000 description 6
- 238000012986 modification Methods 0.000 description 5
- 230000004048 modification Effects 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 210000001165 lymph node Anatomy 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 102000003982 Parathyroid hormone Human genes 0.000 description 3
- 208000024770 Thyroid neoplasm Diseases 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000199 parathyroid hormone Substances 0.000 description 3
- 229960001319 parathyroid hormone Drugs 0.000 description 3
- 201000002510 thyroid cancer Diseases 0.000 description 3
- 208000000038 Hypoparathyroidism Diseases 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 208000009453 Thyroid Nodule Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 230000000849 parathyroid Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/009—Various features of diagnostic instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
Abstract
The invention discloses a portable PTH detection device in an operation process, which comprises a detection box, a detection device and a detection device, wherein the detection box comprises a box body, a test strip and a negative pressure cavity, the negative pressure cavity is communicated with an opening arranged on the side surface of the box body through a negative pressure pipeline, a bottom cavity is also arranged in the box body, and the bottom cavity is communicated with the negative pressure pipeline through a through hole; the test strip is arranged in the bottom cavity; the sampling needle comprises a needle head, a hose and a connecting end head, the hose is connected with the needle head and the connecting end head, and an inserting column is arranged at the end part of the connecting end head; the invention can quickly sample and detect in real time.
Description
Technical Field
The invention relates to the technical field of fire safety, in particular to a portable PTH detection device in an operation process.
Background
In recent years, the incidence of thyroid nodules, particularly thyroid cancer, has increased rapidly, and patients who require a total thyroidectomy or cervical lymphadenectomy have increased. Some patients have secondary hypoparathyroidism caused by the mistaken cutting and damage of parathyroid gland in thyroid operation or because of the change of blood supply, and the secondary hypoparathyroidism is always a serious complication after the thyroid operation. The patients with mild clinical manifestations have hand and foot numbness and convulsion, and the patients with severe manifestations can endanger life, bring great physical and psychological pains to the patients, and bring great working and psychological pressure to the patients.
In the process of thyroid surgery, especially in the operation of cleaning central lymph nodes of thyroid cancer, how to identify and avoid the damage of parathyroid gland is always the key and difficult point of domestic and foreign operations. At present, the parathyroid gland is identified by surgeons mainly by subjective experience, and the parathyroid gland is protected by fine dissection. In case of thyroid cancer, central lymph node cleaning, especially bilateral lymph cleaning, is required, and damage to parathyroid glands, especially lower parathyroid glands, is almost unavoidable, and is basically in the range of lymph node cleaning. Therefore, it is of utmost importance to identify and protect the parathyroid gland correctly during surgery.
Parathyroid hormone is secreted from the main cells in parathyroid tissue, while surrounding tissues such as fat, lymph nodes, thyroid gland, etc. do not secrete parathyroid hormone. Therefore, the parathyroid gland can be effectively identified by rapidly detecting parathyroid hormone in the operation, and the prior art mostly needs to be sent to a laboratory for testing after sampling and cannot rapidly detect in real time.
Disclosure of Invention
This section is for the purpose of summarizing some aspects of embodiments of the invention and to briefly introduce some preferred embodiments, and in this section as well as in the abstract and the title of the invention of this application some simplifications or omissions may be made to avoid obscuring the purpose of this section, the abstract and the title of the invention, and such simplifications or omissions are not intended to limit the scope of the invention.
The present invention has been made keeping in mind the above problems occurring in the prior art and/or the problems occurring in the prior art.
Therefore, the technical problem to be solved by the invention is that the rapid detection of the sampled tissue fluid is difficult in the existing thyroid surgery process.
In order to solve the technical problems, the invention provides the following technical scheme: a portable PTH detection device in the operation process comprises a detection box, a detection device and a detection device, wherein the detection box comprises a box body, a test strip and a negative pressure cavity, the negative pressure cavity is communicated with an opening arranged on the side surface of the box body through a negative pressure pipeline, a bottom cavity is further arranged in the box body, and the bottom cavity is communicated with the negative pressure pipeline through a through opening; the test strip is arranged in the bottom cavity;
the sampling needle, the sampling needle includes syringe needle, hose and connection end, hose connection syringe needle and connection end.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: the box body is also provided with a sliding cavity, the sliding cavity is internally provided with a diluting box, and the diluting box is internally provided with a diluting liquid.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: the sliding cavity is communicated with the negative pressure pipeline through a first channel and a second channel;
dilute box one end and be provided with first pillar pipe and second pillar pipe, first pillar pipe set up in the first channel, second pillar pipe set up in the second channel.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: the button cell comprises a first channel and a second channel, wherein the first channel is provided with a first electromagnetic valve, the second channel is provided with a second electromagnetic valve, and the first electromagnetic valve and the second electromagnetic valve are both connected with the button cell.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: and a first contact and a second contact are arranged in the negative pressure pipeline, and the first contact and the second contact are connected with the first electromagnetic valve, the second electromagnetic valve and the button cell in series.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: and a third column tube is arranged outside the opening.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: and a rubber seal layer is arranged in the third column tube.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: a column cavity is arranged in the connecting end, and the third column pipe is embedded in the column cavity.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: an insertion pipe is arranged in the column cavity, and a through groove is formed in the insertion pipe and communicated with the hose.
As a preferable aspect of the portable PTH detection apparatus during a surgical procedure of the present invention, wherein: and the box body is provided with an observation hole corresponding to the test strip.
The invention has the beneficial effects that: the invention can quickly sample and detect in real time.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise. Wherein:
FIG. 1 is a schematic view of an overall assembly structure of a portable PTH detection device during a surgical procedure according to an embodiment of the present invention;
FIG. 2 is a schematic cross-sectional view of a portable PTH detection device during a surgical procedure according to an embodiment of the present invention;
FIG. 3 is a schematic structural diagram of a sampling needle of the portable PTH detection device during a surgical procedure according to an embodiment of the present invention;
FIG. 4 is a schematic view of the internal structure of a cartridge of the portable PTH detection apparatus during a surgical procedure according to an embodiment of the present invention;
FIG. 5 is a schematic structural diagram of a dilution box of the portable PTH detection device during the operation according to one embodiment of the present invention;
fig. 6 is a schematic circuit connection diagram of a solenoid valve in the portable PTH detection apparatus during a surgical procedure according to an embodiment of the present invention.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, but the present invention may be practiced in other ways than those specifically described and will be readily apparent to those of ordinary skill in the art without departing from the spirit of the present invention, and therefore the present invention is not limited to the specific embodiments disclosed below.
Next, the present invention will be described in detail with reference to the drawings, wherein the cross-sectional views illustrating the structure of the device are not enlarged partially according to the general scale for convenience of illustration when describing the embodiments of the present invention, and the drawings are only examples, which should not limit the scope of the present invention. In addition, the three-dimensional dimensions of length, width and depth should be included in the actual fabrication.
Further, reference herein to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one implementation of the invention. The appearances of the phrase "in one embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments.
Example 1
Referring to fig. 1 to 6, the embodiment provides a portable PTH detection device in an operation process, including a detection box 100, including a box body 101, a test strip 102 and a negative pressure cavity 103, where the negative pressure cavity 103 is communicated with an opening 101a disposed on a side surface of the box body 101 through a negative pressure pipeline 104, the box body 101 is further provided with a bottom cavity 101c, and the bottom cavity 101c is communicated with the negative pressure pipeline 104 through a through hole 101 b; the test strip 102 is disposed in the bottom cavity 101 c;
The box body 101 is also provided with a sliding cavity 105, the sliding cavity 105 is provided with a diluting box A, and the diluting box A is provided with a diluting liquid.
The slide chamber 105 communicates with the negative pressure pipe 104 through a first channel 106 and a second channel 107;
the dilution box a is provided at one end with a first column tube 105a and a second column tube 105b, the first column tube 105a being disposed in the first channel 106, the second column tube 105b being disposed in the second channel 107.
A first electromagnetic valve 106a is arranged in the first channel 106, a second electromagnetic valve 107a is arranged in the second channel 107, and the first electromagnetic valve 106a and the second electromagnetic valve 107a are both connected with the button battery B.
The negative pressure pipeline 104 is provided with a first contact 104a and a second contact 104B, and the first contact 104a and the second contact 104B are connected in series with a first electromagnetic valve 106a, a second electromagnetic valve 107a and a button battery B.
A third cylinder 101d is provided outside the opening 101 a.
A rubber seal 101e is provided in the third column tube 101 d.
The connection end 203 is provided with a column cavity 203a, and the third column tube 101d is embedded in the column cavity 203 a.
A cannula 203b is arranged in the column cavity 203a, and a through groove 203c is arranged in the cannula 203b and communicated with the hose 202.
The box body 101 is provided with an observation hole C corresponding to the test strip 102.
A third electromagnetic valve 104c is also arranged in the negative pressure pipeline 104.
It should be noted that, in the initial state, the first electromagnetic valve 106a and the second electromagnetic valve 107a are in the closed state, the diluent is blocked in the dilution box a, the third electromagnetic valve 104c is in the open state, the negative pressure chamber 103 is communicated to the opening 101a, and the rubber sealing layer 101e is arranged at the opening 101a for blocking, that is, the negative pressure pipeline 104 and the negative pressure chamber 103 in the box body 101 are both in the negative pressure state compared with the outside.
It should be noted that the detection box 100 and the sampling needle 200 are packaged separately, and in use, the two are taken out, the connection end 203 is sleeved into the third cylinder 101d, and the insertion tube 203b penetrates through the rubber seal 101e, so that the through groove 203c is communicated with the negative pressure pipeline 104.
In practical use, the needle 201 needs to be inserted into the thyroid gland area, the connecting end 203 is sleeved into the third cylindrical tube 101d, the sample tissue is sucked into the negative pressure pipeline 104 under negative pressure, the sample tissue enables the circuit of fig. 6 to be communicated through the first contact 104a and the second contact 104b, the first electromagnetic valve 106a and the second electromagnetic valve 107a are powered on and opened, and the third electromagnetic valve 104C is powered on and closed, so that the sample tissue enters the dilution box a through the first channel 106 and enters the negative pressure pipeline 104 together with the diluent through the second channel 107, the sample tissue is mixed with the diluent in the process and diluted, the diluent is detected by the test strip 102 through the through hole 101b, and the detection result is observed from the observation hole C.
It is important to note that the construction and arrangement of the present application as shown in the various exemplary embodiments is illustrative only. Although only a few embodiments have been described in detail in this disclosure, those skilled in the art who review this disclosure will readily appreciate that many modifications are possible (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, values of parameters (e.g., temperatures, pressures, etc.), mounting arrangements, use of materials, colors, orientations, etc.) without materially departing from the novel teachings and advantages of the subject matter recited in this application. For example, elements shown as integrally formed may be constructed of multiple parts or elements, the position of elements may be reversed or otherwise varied, and the nature or number of discrete elements or positions may be altered or varied. Accordingly, all such modifications are intended to be included within the scope of this invention. The order or sequence of any process or method steps may be varied or re-sequenced according to alternative embodiments. In the claims, any means-plus-function clause is intended to cover the structures described herein as performing the recited function and not only structural equivalents but also equivalent structures. Other substitutions, modifications, changes and omissions may be made in the design, operating conditions and arrangement of the exemplary embodiments without departing from the scope of the present inventions. Therefore, the present invention is not limited to a particular embodiment, but extends to various modifications that nevertheless fall within the scope of the appended claims.
Moreover, in an effort to provide a concise description of the exemplary embodiments, all features of an actual implementation may not be described (i.e., those unrelated to the presently contemplated best mode of carrying out the invention, or those unrelated to enabling the invention).
It should be appreciated that in the development of any such actual implementation, as in any engineering or design project, numerous implementation-specific decisions may be made. Such a development effort might be complex and time consuming, but would nevertheless be a routine undertaking of design, fabrication, and manufacture for those of ordinary skill having the benefit of this disclosure, without undue experimentation.
It should be noted that the above-mentioned embodiments are only for illustrating the technical solutions of the present invention and not for limiting, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, which should be covered by the claims of the present invention.
Claims (10)
1. A portable PTH detection apparatus during a surgical procedure, comprising: comprises the steps of (a) preparing a mixture of a plurality of raw materials,
the detection box (100) comprises a box body (101), a test strip (102) and a negative pressure cavity (103), wherein the negative pressure cavity (103) is communicated with an opening (101 a) arranged on the side surface of the box body (101) through a negative pressure pipeline (104), a bottom cavity (101 c) is further arranged in the box body (101), and the bottom cavity (101 c) is communicated with the negative pressure pipeline (104) through a through opening (101 b); the test strip (102) is arranged in the bottom cavity (101 c);
sampling needle (200), sampling needle (200) include syringe needle (201), hose (202) and connection end (203), hose (202) connection syringe needle (201) and connection end (203).
2. The device of claim 1, wherein the portable PTH detection device is configured to: still be provided with in the box body (101) and slide chamber (105), be provided with in slide chamber (105) and dilute box (A), be provided with the diluent in diluting box (A).
3. The device for the detection of portable PTH during surgery of claim 1 or 2, wherein: the sliding cavity (105) is communicated with the negative pressure pipeline (104) through a first channel (106) and a second channel (107);
one end of the dilution box (A) is provided with a first column tube (105 a) and a second column tube (105 b), the first column tube (105 a) is arranged in the first channel (106), and the second column tube (105 b) is arranged in the second channel (107).
4. The device of claim 3, wherein the portable PTH detection device is further characterized by: the button cell switch is characterized in that a first electromagnetic valve (106 a) is arranged in the first channel (106), a second electromagnetic valve (107 a) is arranged in the second channel (107), and the first electromagnetic valve (106 a) and the second electromagnetic valve (107 a) are both connected with a button cell (B).
5. The device of claim 4, wherein the portable PTH detection device is further characterized by: the negative pressure pipeline (104) is internally provided with a first contact (104 a) and a second contact (104B), and the first contact (104 a) and the second contact (104B) are connected with a first electromagnetic valve (106 a), a second electromagnetic valve (107 a) and a button battery (B) in series.
6. The device of claim 5, wherein the portable PTH detection device is further characterized by: and a third column tube (101 d) is arranged outside the opening (101 a).
7. The device for detecting portable PTH during surgery according to any one of claims 4 to 6, wherein: and a rubber seal layer (101 e) is arranged in the third column tube (101 d).
8. The device of claim 7, wherein the portable PTH detection device is configured to: a column cavity (203 a) is formed in the connecting end head (203), and the third column tube (101 d) is embedded in the column cavity (203 a).
9. The device of claim 8, wherein the portable PTH detection device is configured to: an insertion pipe (203 b) is arranged in the column cavity (203 a), and a through groove (203 c) is arranged in the insertion pipe (203 b) and communicated with the hose (202).
10. The device for the detection of portable PTH during surgery of claims 8 or 9, wherein: an observation hole (C) is formed in the position, corresponding to the test strip (102), of the box body (101).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111112417.3A CN113907798B (en) | 2021-09-23 | 2021-09-23 | Portable PTH detection device in operation process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111112417.3A CN113907798B (en) | 2021-09-23 | 2021-09-23 | Portable PTH detection device in operation process |
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| Publication Number | Publication Date |
|---|---|
| CN113907798A true CN113907798A (en) | 2022-01-11 |
| CN113907798B CN113907798B (en) | 2024-02-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202111112417.3A Active CN113907798B (en) | 2021-09-23 | 2021-09-23 | Portable PTH detection device in operation process |
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| CN111329562A (en) * | 2020-03-16 | 2020-06-26 | 贺菲菲 | Combined device for thyroid puncture |
| CN211535864U (en) * | 2019-12-31 | 2020-09-22 | 重庆市人民医院 | Sputum suction tube with test paper |
| CN112629940A (en) * | 2020-12-17 | 2021-04-09 | 云智动(杭州)科技有限公司 | Sputum sampling detection device and use method thereof |
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2021
- 2021-09-23 CN CN202111112417.3A patent/CN113907798B/en active Active
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1370278A (en) * | 1999-08-11 | 2002-09-18 | 旭化成株式会社 | Analyzing cartridge and liquid feed control device |
| CN103808947A (en) * | 2014-03-11 | 2014-05-21 | 爱威科技股份有限公司 | Test strip sample pouring groove, drying analyzer and sampling pouring and cleaning method of drying analyzer |
| CN204177806U (en) * | 2014-07-22 | 2015-02-25 | 三诺生物传感股份有限公司 | A kind of immunity-chromatography test strip |
| CN105708477A (en) * | 2016-04-08 | 2016-06-29 | 杜东 | Portable negative pressure blooding sampling detection integrated glucometer |
| US20180074074A1 (en) * | 2016-09-13 | 2018-03-15 | Insight Instruments, Inc. | Homogenous and heterogeneous assays and systems for determination of ocular biomarkers |
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| Publication number | Publication date |
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| CN113907798B (en) | 2024-02-23 |
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