CN113893418B

CN113893418B - Spray device

Info

Publication number: CN113893418B
Application number: CN202111456057.9A
Authority: CN
Inventors: 卓力; 郑义才
Original assignee: Imotion Shanghai Product Design Co ltd
Current assignee: Imotion Shanghai Product Design Co ltd
Priority date: 2021-12-02
Filing date: 2021-12-02
Publication date: 2022-07-12
Anticipated expiration: 2041-12-02
Also published as: CN113893418A

Abstract

The invention provides a spray device, which comprises a capsule and a base suitable for mounting the capsule; the capsule comprises a nozzle, a first reagent cavity suitable for containing a reagent, a second reagent cavity respectively communicated with the first reagent cavity and the nozzle, and a first piston assembly positioned in the second reagent cavity; the base comprises a connecting component suitable for being magnetically connected with the first piston component, a gas cavity communicated with the connecting component, and a second piston component at least partially positioned in the gas cavity; the first piston assembly includes a first air passage; the connecting assembly comprises a second air passage respectively communicated with the first air passage and the air cavity; at least one of the first air passage and the second air passage is provided with a pressure valve; the second piston assembly is suitable for being pressed to compress the gas in the gas cavity to push the first piston assembly to move towards the direction away from the connecting assembly; and then the reagent in the second reagent cavity is pushed to move, so that the reagent is sprayed out from the second reagent cavity along the nozzle, and deep non-invasive drug delivery is realized.

Description

Spray device

Technical Field

The invention relates to the technical field of spraying agent devices.

Background

The blood-brain barrier is a natural barrier between the systemic circulation and the central nervous system, but it acts as a barrier and prevents many drugs from entering the central nervous system for therapeutic purposes. The traditional administration methods, such as transcranial in-situ injection, subarachnoid injection and the like, are difficult to be widely applied to clinical patients due to strong traumatism, high operation technical requirements and the like.

A large number of clinical researches find that the nasal cavity olfactory region is a position where nerve cells are directly contacted with the surrounding environment, so that the possibility that the medicine avoids the blood brain barrier and enters the brain through the nasal cavity is realized. At present, the existing nasal administration technology is widely applied. However, current nasal delivery devices either require intrusion into the nasal cavity or do not allow for true deep delivery.

Disclosure of Invention

The invention provides a spray device, which can realize deep administration of a medicine reaching a target area such as an olfactory region by driving a reagent to form a high-speed linear jet flow through high-pressure air, does not need to invade a human body such as a nasal cavity during administration, is safe and sanitary, can realize selection of multiple spray modes by combining a high-speed linear jet flow mode and an atomized oscillating spray mode, can select one of the high-speed linear jet flow mode and the atomized oscillating spray mode, can simultaneously select the high-speed linear jet flow mode and the atomized oscillating spray mode, and can realize quantitative administration of the high-speed linear jet flow mode by arranging a through hole between a first reagent cavity and a second reagent cavity.

Therefore, the embodiment of the invention provides the following technical scheme:

an object of an embodiment of the present invention is to provide a spray device. The spray device includes a capsule and a base adapted to mount the capsule; the capsule comprises a nozzle, a first reagent cavity suitable for containing a reagent, a second reagent cavity respectively communicated with the first reagent cavity and the nozzle, and a first piston assembly positioned in the second reagent cavity; the base comprises a connecting assembly adapted to magnetically connect to the first piston assembly, a gas chamber adapted to communicate with the connecting assembly, and a second piston assembly at least partially located within the gas chamber; wherein the first piston assembly includes a first air passage; the connecting assembly comprises a second air passage respectively communicated with the first air passage and the air cavity; at least one of the first air passage and the second air passage is provided with a pressure valve; the second piston assembly is adapted to be depressed to compress the gas in the gas chamber to a cracking pressure threshold to open the pressure valve and to urge the first piston assembly to move away from the connecting assembly against the magnetic attraction between the first piston assembly and the connecting assembly; the first piston assembly is suitable for pushing the reagent in the second reagent cavity to move when moving in the direction away from the connecting assembly, so that the reagent is sprayed out of the second reagent cavity along the nozzle; the capsule also comprises a partition wall suitable for separating the first reagent cavity from the second reagent cavity, and the partition wall is provided with a through hole for communicating the first reagent cavity with the second reagent cavity; the first piston assembly is suitable for moving under the driving of gas entering the first gas channel to close the through hole; the first reagent cavity is communicated with the nozzle; the capsule also comprises an atomization oscillating sheet positioned in the first reagent cavity so as to atomize the reagent in the first reagent cavity and then spray the reagent along the nozzle.

Optionally, the first air passage is in communication with the second reagent chamber; the second piston assembly is suitable for being pressed to compress the gas in the gas cavity, so that the gas enters the second reagent cavity through the second gas channel and the first gas channel in sequence to drive the reagent in the second reagent cavity to be sprayed out from the second reagent cavity along the nozzle.

Optionally, the pressure valve comprises a first pressure valve; the first piston assembly comprises a first piston arranged in the second reagent cavity and suitable for arranging a first air passage and a first pressure valve arranged in the first air passage; the first pressure valve is suitable for being driven by gas from the second gas passage to be opened so as to enable the second gas passage to be communicated with the first gas passage; the first piston is adapted to be driven by gas entering the first gas passage to move in the second reagent chamber to move the reagent in the second reagent chamber, so that the reagent is ejected from the second reagent chamber along the nozzle.

Optionally, the pressure valve comprises a second pressure valve; the connecting assembly comprises a second pressure valve arranged on the second air passage; the second pressure valve is adapted to be driven open by gas from the gas chamber or the second gas passage to communicate the second gas passage with the first gas passage.

Optionally, the first piston assembly is adapted to move in a direction away from the connection assembly to magnetically separate from the connection assembly and urge the reagent in the second reagent chamber to move under the drive of the gas into the first gas passage and to move in a direction towards the connection assembly to magnetically connect with the connection assembly based on magnetic attraction upon the drive of the gas being removed.

Optionally, the second piston assembly comprises a drive mechanism and a resilient member; the driving mechanism comprises a second piston positioned in the gas cavity, a manual button suitable for being pressed and a connecting rod for connecting the second piston and the manual button; the elastic piece is arranged around the connecting rod; the manual button is suitable for being pressed to compress the elastic piece and drive the second piston to compress the gas in the gas cavity; the elastic element is suitable for restoring the compression when being pressed and withdrawn so as to drive the driving mechanism to reset.

Optionally, the second piston assembly comprises a one-way valve mounted to the second piston; the one-way valve is adapted to be open towards the gas chamber and is adapted to direct gas outside the gas chamber into the gas chamber at least when the drive mechanism is reset.

Optionally, the capsule comprises a transition chamber between the first reagent chamber and the nozzle; the capsule comprises a nozzle communicated with the second reagent cavity; the nozzle pipe passes through the transition cavity and is communicated with the nozzle.

Optionally, the base comprises an electronic control module adapted to be electrically connected to the atomizing oscillating plate to control the atomizing oscillating plate to atomize the reagent in the first reagent chamber.

Compared with the prior art, the technical scheme of the embodiment of the invention has the beneficial effect.

For example, with the spray device provided by the embodiment of the invention, the high-pressure air can drive the reagent to form a high-speed linear jet flow so as to realize deep administration reaching a target area such as an olfactory region, and the spray device is safe and sanitary without invading human bodies such as nasal cavities during administration.

For another example, by adopting the spray device provided by the embodiment of the invention, the dosage of each time can be controlled through the volume of the second reagent cavity, so that the use is convenient.

For another example, by using the spray device provided by the embodiment of the invention, the administration of the mixed spray can be realized by combining a high-speed linear jet flow and a vibration atomization mode.

For another example, the spray device provided by the embodiment of the invention is suitable for administration of not only liquid reagents but also powder reagents.

For another example, the spray device provided by the embodiment of the invention is not only suitable for nasal administration, but also suitable for administration at throat and administration in any other applicable scenes.

For another example, the spray device provided by the embodiment of the invention has the advantages of simple structure, easy realization, convenient use and carrying, and wide popularization and application.

Drawings

Fig. 1 is a cross-sectional view of a spray device in accordance with an embodiment of the present invention in a non-use state;

fig. 2 is a cross-sectional view of a spray device in an embodiment of the present invention in use;

fig. 3 is another cross-sectional view of a spray device in an embodiment of the present invention in use.

Description of reference numerals:

10 a spray device;

100 capsules, 110 capsule shells, 120 nozzles, 130 first reagent cavities, 140 second reagent cavities, 150 first piston components, 151 first air passages, 152 first pistons, 153 first magnets, 160 partition walls, 161 through holes, 170 spray pipes, 180 atomization oscillating plates and 190 transition cavities;

200 base, 210 base housing, 220 connecting component, 221 second air channel, 222 second pressure valve, 223 second magnet, 230 gas cavity, 240 second piston component, 241 second piston, 242 manual button, 243 connecting rod, 244 elastic component, 245 one-way valve;

300 electronic control module, 310 keys, 320 circuit board, 330 battery, 340 first electric connection contact.

Detailed Description

In order to make the objects, features and advantages of the present invention more comprehensible, embodiments accompanying the drawings are described in detail below. It is to be understood that the following detailed description is only illustrative of the invention and is not to be taken in a limiting sense. Also, descriptions of the same or similar components in different embodiments and descriptions of components, features, effects, and the like belonging to the related art may be omitted. In addition, for convenience of description, only a part, not all of the structure related to the present invention is shown in the drawings.

Fig. 1 is a cross-sectional view of a spray device in accordance with an embodiment of the present invention in a non-use state; fig. 2 is a cross-sectional view of a spray device in an embodiment of the present invention in use; fig. 3 is another cross-sectional view of a spray device in an embodiment of the present invention in use.

Fig. 2 illustrates a situation when the second piston assembly of the spray device is pressed to compress the gas in the gas chamber and the reagent in the spray device has not yet been sprayed. In this case, the gas pressure generated by the second piston assembly compressing the gas in the gas chamber is not yet sufficient to drive the first piston assembly to move.

Fig. 3 illustrates the spray device when the second piston assembly is actuated to compress the gas in the gas chamber and the reagent in the spray device is sprayed. In this case, the gas pressure generated by the second piston assembly compressing the gas in the gas chamber is sufficient to drive the first piston assembly to move.

Referring to fig. 1 to 3, an embodiment of the present invention provides a spray device 10.

Specifically, the spray device 10 includes a capsule 100 and a base 200 adapted to mount the capsule 100.

Capsule 100 includes a capsule housing 110, a nozzle 120 located on capsule housing 110, a first reagent chamber 130 located within capsule housing 110 and adapted to contain a reagent, a second reagent chamber 140 located within capsule housing 110 and in communication with first reagent chamber 130 and nozzle 120, respectively, and a first piston assembly 150 located within second reagent chamber 140.

The base 200 includes a base housing 210, a connection assembly 220 mounted to the base housing 210 and adapted to connect to the first piston assembly 150, a gas chamber 230 located within the base housing 210 and adapted to communicate with the connection assembly 220, and a second piston assembly 240 mounted to the base housing 210 and at least partially located within the gas chamber 230.

In a specific implementation, the first reagent chamber 130 is located within the capsule housing 110 and is adapted to contain a reagent. A second reagent chamber 140 is also located within the capsule housing 110 and is in communication with the nozzle 120 on the capsule housing 110 and the first reagent chamber 130, respectively.

Referring to fig. 2, in some embodiments, the capsule 100 can include a partition wall 160 located within the capsule housing 110 and adapted to separate the first and

second reagent chambers

130, 140. The partition wall 160 is further provided with a through hole 161 to communicate the first reagent chamber 130 with the second reagent chamber 140.

In some embodiments, partition wall 160 may be vertically disposed, and through-holes 161 may be located at or near the bottom of partition wall 160. In this way, the first reagent chamber 130 and the second reagent chamber 140 can be made to communicate at the bottom of the two or a position close to the bottom, so that the reagent in the first reagent chamber 130 can flow to the second reagent chamber 140 through the through hole 161 based on the principle of a communicating vessel.

In some embodiments, capsule 100 further comprises a spout 170 positioned within capsule housing 110 and having two ends in communication with nozzle 110 and second reagent chamber 140, respectively. In this manner, reagent in the second reagent chamber 140 can be caused to pass through the spout 170 to the nozzle 120.

In a specific implementation, the first piston assembly 150 is disposed in the second reagent chamber 140 and is adapted to move under the action of the base 200 to push the reagent in the second reagent chamber 140 to move, so as to eject the reagent from the second reagent chamber 140 along the nozzle 120.

In a specific implementation, the first piston assembly 150 includes a first air passage 151. The connection assembly 220 of the base 200 includes a second air passage 221 communicating with the first air passage 151 and the gas chamber 230, respectively. The second piston assembly 240 is adapted to be depressed to compress the gas in the gas chamber 230 and to cause the gas to enter the first gas passage 151 via the second gas passage 221, thereby driving the first piston assembly 150 to move to force the reagent in the second reagent chamber 140 to move, and thereby cause the reagent in the second reagent chamber 140 to be ejected from the second reagent chamber 140 along the nozzle 120.

Thus, the second piston assembly 240 can be pushed to compress the gas in the gas chamber 230, thereby driving the first piston assembly 150 to move, and further pushing the reagent in the second reagent chamber 140 to move so as to eject the reagent along the nozzle 120.

In some embodiments, the first gas channel 151 may also be in communication with the second reagent chamber 140. Accordingly, the second piston assembly 240 is further adapted to be pressed to compress the gas in the gas chamber 230 to cause the gas to enter the second reagent chamber 140 through the second gas passage 221 and the first gas passage 151 in sequence, thereby driving the reagent in the second reagent chamber 140 to be ejected from the second reagent chamber 140 along the nozzle 120.

In this case, by pressing the second piston assembly 240 to compress the gas in the gas chamber 230, not only the first piston assembly 150 can be driven to move, thereby pushing the reagent in the second reagent chamber 140 to move so as to eject the reagent along the nozzle 120, but also the reagent in the second reagent chamber 140 can be directly driven to eject along the nozzle 120.

In particular implementations, the first piston assembly 150 and/or the gas from the gas chamber 230 are adapted to drive the reagent in the second reagent chamber 140 in a linear jet out of the nozzle 120.

In some embodiments, the reagent may comprise a powdered reagent. In this case, the linear jet ejected from the nozzle 120 may include a powder jet.

In other embodiments, the reagent may also include a liquid reagent. In this case, the linear jet ejected from the nozzle 120 may include a liquid jet.

It will be appreciated that in implementations, the particle size of the liquid or powder in the linear jet may also be controlled by controlling the pressure of the compressed gas and/or the orifice size of the nozzle 120.

In some embodiments, the liquid jet may comprise a liquid jet in an atomized state having a particle size that is the same as or similar to the particle size of the reagent after atomization. Thus, the reagent can be sprayed out to have a spraying effect.

In other embodiments, the liquid spray may also include a non-atomized spray having a larger particle size than an atomized spray. In this way, the reagent can be ejected with a long range, and thus the reagent can be supplied at a long distance, that is, deep drug administration can be performed well.

In some embodiments, the first piston assembly 150 includes a first piston 152 disposed within the second reagent chamber 140 and adapted to dispose a first air passage 151, and a first pressure valve mounted to the first air passage 151.

In a specific implementation, the first pressure valve is adapted to be driven to open by gas from the second gas passage 221 to communicate the second gas passage 221 with the first gas passage 151. The first piston 152 is adapted to be moved within the second reagent chamber 140 by gas entering the first gas passage 151 to force the reagent within the second reagent chamber 140 to move.

It will be appreciated that the first pressure valve is adapted to open when the pressure of the gas from the second gas passage 221 reaches its cracking pressure threshold, thereby placing the second gas passage 221 in communication with the first gas passage 151. In this way, the gas entering the first gas channel 151 through the second gas channel 221 has a higher pressure, so that the reagent in the second reagent chamber 140 can be ejected along the nozzle 120 at a higher speed, and the ejected stream along the nozzle 120 has a longer range, thereby better realizing long-distance deep drug delivery.

In some embodiments, the first piston assembly 150 may be a suitable interference fit with the second reagent chamber 140 such that the first piston assembly 150 is able to move towards the nozzle 120 and/or the lance 170 under the drive of gas entering the first gas passage 151, thereby urging reagent within the second reagent chamber 140 to be ejected along the nozzle 120.

In some embodiments, connection assembly 220 further includes a second pressure valve 222 mounted to second air passageway 221. The second pressure valve 222 is adapted to be driven by the gas from the gas chamber 230 or the second gas passage 221 to open so as to communicate the second gas passage 221 with the first gas passage 151, so that the gas from the gas chamber 230 enters the first gas passage 151 through the second gas passage 221.

It will be appreciated that the second pressure valve 222 is also adapted to open when the pressure of the gas from the gas chamber 230 or the second gas passage 221 reaches its cracking pressure threshold, thereby allowing the second gas passage 221 and the first gas passage 151 to communicate. In this way, the gas entering the first gas channel 151 through the second gas channel 221 can have a higher pressure, so that the reagent in the second reagent chamber 140 can be ejected along the nozzle 120 at a higher speed, and the ejected stream along the nozzle 120 has a longer range, thereby achieving a better long-distance and deep drug delivery.

In some embodiments, the first piston assembly 150 is magnetically coupled to the coupling assembly 220. Also, the first piston assembly 150 is adapted to move in a direction away from the coupling assembly 220 to magnetically separate from the coupling assembly 220 and push the reagent in the second reagent chamber 140 to move under the driving of the gas entering the first gas duct 151 and to move in a direction toward the coupling assembly 220 to magnetically couple with the coupling assembly 220 based on the magnetic attraction force after the driving of the gas is removed.

In this manner, the first piston assembly 150 may be automatically reset based on the magnetic attraction with the connection assembly 220 after the reagent in the second reagent chamber 140 is ejected along the nozzle 120 and magnetically connected with the connection assembly 220 after being reset.

It will be appreciated that when the force pressing the second piston assembly 240 is removed, the actuation of the first piston assembly 150 by the gas is correspondingly removed.

In some embodiments, the first piston assembly 150 may include a first magnet 153 mounted to the first piston 152 or the first pressure valve. The coupling assembly 220 may include a second magnet 223 mounted to a second pressure valve 222. Also, the first magnet 153 and the second magnet 223 have opposite magnetic poles at opposite ends thereof.

In some embodiments, second piston assembly 240 may include a drive mechanism and a resilient member 244. Wherein the driving mechanism includes a second piston 241 located in the gas chamber 230, a manual button 242 partially exposed outside the base housing 210 and adapted to be pressed, and a connecting rod 243 connecting the second piston 241 and the manual button 242.

In a particular implementation, the elastic member 244 is disposed around the link 243. The manual button 242 is adapted to be pushed to move to compress the elastic member 244 and drive the second piston 241 to compress the gas in the gas chamber 230. The resilient member 244 is adapted to be compressed by the manual button 242 when the manual button 242 is moved and to return to compression when the manual button 242 is removed to reset the drive mechanism.

In some embodiments, second piston assembly 240 may further include a one-way valve 245 mounted to second piston 241.

In a specific implementation, the one-way valve 245 is adapted to be open to the gas chamber 230 and to direct gas outside the gas chamber 230 into the gas chamber 230 at least when the drive mechanism is reset.

When the reagent in the second reagent chamber 140 is driven to be ejected along the nozzle 120 by compressing the gas in the gas chamber 230 by pressing the second piston assembly 240, the volume of the gas chamber 230 is gradually reduced with the movement of the second piston 241. As the volume of the gas chamber 230 is gradually decreased, the gas pressure within the gas chamber 230 is also gradually decreased.

When the pressing of the second piston assembly 240 is removed, the second piston 241 is gradually restored by the elastic member 244. When the second piston 241 is gradually reset, since the air pressure inside the air cavity 230 is smaller and smaller than the air pressure outside the air cavity 230, the air outside the air cavity 230 enters the air cavity 230 through the check valve 245 until the air pressure inside the air cavity 230 is the same as the air pressure outside the air cavity 230.

In some embodiments, the first piston assembly 150 is further adapted to close the through-hole 161 when moved by the gas entering the first gas passage 151. For example, the first piston 152 in the first piston assembly 150 may be driven to move by the gas, and gradually cover and close the through hole 161 while moving.

In this manner, the reagent in the first reagent chamber 130 may not enter the second reagent chamber 140 during a single use of the spray device 10, such that the maximum amount of reagent ejected along the nozzle 120 during a single use is the volume of the second reagent chamber 140.

In specific implementation, the volume of the second reagent chamber 140 is smaller than the volume of the first reagent chamber 130, and the second reagent chamber 140 and the first reagent chamber 130 are communicated at a position close to the bottoms of the two, so that the reagent in the first reagent chamber 130 can smoothly enter the second reagent chamber 140 in a non-use state.

In the using state, the first piston assembly 150 seals the through hole 161 between the first reagent chamber 130 and the second reagent chamber 140 when moving, so that the reagent in the first reagent chamber 130 cannot enter the second reagent chamber 140, and the maximum amount of the reagent ejected from the nozzle 120 is the volume of the second reagent chamber 140.

In a specific implementation, the opening pressure threshold of the first pressure valve, the opening pressure threshold of the second pressure valve, and/or the volume of the gas cavity 230 may be adjusted so that the reagent in the second reagent cavity 140 is completely ejected during one use, so that the dosage of each time can be determined based on the volume of the second reagent cavity 140.

In some embodiments, the first reagent chamber 130 may also be in communication with the nozzle 120. Also, capsule 100 may further include an atomizing vibration plate 180 positioned within first reagent chamber 130. The atomizing oscillating plate 180 is adapted to atomize the reagent in the first reagent chamber 130 and then eject the reagent along the nozzle 120.

In some embodiments, capsule 100 may further comprise a transition chamber 190 located between first reagent chamber 130 and nozzle 120. Also, capsule 100 further includes a spout 170 in communication with second reagent chamber 140. The nozzle 170 is adapted to communicate with the nozzle 120 through a transition cavity 190.

In some embodiments, both the linear jet of reagent in the second reagent chamber 140 and the spray of reagent in the first reagent chamber 130 are adapted to be ejected along the nozzle 120.

In a specific implementation, the base 200 further includes an electronic control module 300 adapted to be electrically connected to the atomizing oscillating piece 180 to control the atomizing oscillating piece 180 to atomize the reagent in the first reagent chamber 130.

Specifically, the electronic control module 300 may include a key 310 partially exposed outside the base housing 210, a circuit board 320 located within the base housing 210 and adapted to connect with the key 310, a battery 330 located within the base housing 210 and connected with the circuit board 320, and a first electrical connection contact 340 located within the base housing 210 and connected with the battery 330.

Accordingly, capsule 100 also includes a second electrical connection contact point to which aerosolization oscillating pad 180 is connected. The second electrical connection contact is disposed opposite the first electrical connection contact 340 and is adapted to be electrically connected to the first electrical connection contact.

In a particular implementation, the keys 310 are adapted to be pressed to move toward the circuit board 320 and into contact with the circuit board 320. When the circuit board 320 is in contact with the key 310, the circuit board 320 is adapted to control the second electrical connection contact to be electrically connected with the first electrical connection contact 340 and control the atomizing oscillating plate 180 to generate oscillation to atomize the reagent in the first reagent chamber 130.

While specific embodiments of the invention have been described above, these embodiments are not intended to limit the scope of the disclosure, even if only a single embodiment is described with respect to a particular feature. The characteristic examples provided in the present disclosure are intended to be illustrative, not limiting, unless differently stated. In particular implementations, the features of one or more dependent claims may be combined with those of the independent claims as technically feasible according to the actual requirements, and the features of the respective claims may be combined in any appropriate manner and not merely in the specific combinations enumerated in the claims.

Although the present invention is disclosed above, the present invention is not limited thereto. Various changes and modifications may be effected by one skilled in the art without departing from the spirit and scope of the invention, as defined in the appended claims.

Claims

1. Spray device (10) comprising a capsule (100) and a base (200) adapted to mount the capsule (100);

the capsule (100) comprises a nozzle (120), a first reagent chamber (130) adapted to contain a reagent, a second reagent chamber (140) in communication with the first reagent chamber (130) and the nozzle (120), respectively, and a first piston assembly (150) located within the second reagent chamber (140);

the base (200) comprises a connection assembly (220) adapted to magnetically connect the first piston assembly (150), a gas chamber (230) adapted to communicate with the connection assembly (220), and a second piston assembly (240) at least partially within the gas chamber (230);

wherein the first piston assembly (150) comprises a first gas channel (151); the connecting assembly (220) comprises a second air passage (221) which is communicated with the first air passage (151) and the gas cavity (230) respectively; at least one of the first air passage (151) and the second air passage (221) is provided with a pressure valve;

the second piston assembly (240) is adapted to be pressed to compress a gas within the gas chamber (230) such that the pressure of the gas reaches a cracking pressure threshold to open the pressure valve and to urge the first piston assembly (150) to move away from the connection assembly (220) against the magnetic attraction between the first piston assembly (150) and the connection assembly (220);

the first piston assembly (150) is adapted to urge reagent in the second reagent chamber (140) to move when moved in a direction away from the connecting assembly (220), thereby causing the reagent to be ejected from the second reagent chamber (140) along the nozzle (120);

the capsule (100) further comprises a partition wall (160) adapted to separate the first reagent chamber (130) and the second reagent chamber (140), the partition wall (160) being provided with a through hole (161) to communicate the first reagent chamber (130) and the second reagent chamber (140); the first piston assembly (150) is suitable for moving under the drive of gas entering the first air passage (151) to close the through hole (161);

the first reagent chamber (130) is in communication with the nozzle (120); the capsule (100) further comprises an atomization oscillating sheet (180) positioned in the first reagent cavity (130) so as to atomize the reagent in the first reagent cavity (130) and then enable the reagent to be sprayed out along the nozzle (120).

2. The spray device (10) of claim 1, wherein the first air passage (151) is in communication with the second reagent chamber (140); the second piston assembly (240) is adapted to be depressed to compress gas in the gas chamber (230) so that the gas passes through the second gas passage (221), the first gas passage (151) and into the second reagent chamber (140) in sequence to drive reagent in the second reagent chamber (140) to be ejected from the second reagent chamber (140) along the nozzle (120).

3. The spray device (10) of claim 1 or 2, wherein the pressure valve comprises a first pressure valve; the first piston assembly (150) comprises a first piston (152) disposed within the second reagent chamber (140) and adapted to dispose the first air passage (151), and the first pressure valve mounted to the first air passage (151); the first pressure valve is adapted to be driven to open by the gas from the second gas passage (221) to communicate the second gas passage (221) with the first gas passage (151); the first piston (152) is adapted to be moved within the second reagent chamber (140) by the gas entering the first gas passage (151) to urge movement of reagent within the second reagent chamber (140).

4. The spray device (10) of claim 1 or 2, wherein the pressure valve comprises a second pressure valve (222); the connection assembly (220) comprises the second pressure valve (222) mounted to the second air passage (221); the second pressure valve (222) is adapted to be driven to open by gas from the gas chamber (230) or the second gas duct (221) to communicate the second gas duct (221) with the first gas duct (151).

5. Spray device (10) according to claim 1 or 2, characterized in that the first piston assembly (150) is adapted to move in a direction away from the connection assembly (220) under the drive of the gas entering into the first gas channel (151) to magnetically separate from the connection assembly (220) and to push the reagent in the second reagent chamber (140) to move and to move in a direction towards the connection assembly (220) based on magnetic attraction to magnetically connect with the connection assembly (220) after the drive of the gas is removed.

6. The spray device (10) of claim 1 or 2, wherein the second piston assembly (240) includes a drive mechanism and a resilient member (244); the drive mechanism comprises a second piston (241) located within the gas chamber (230), a manual button (242) adapted to be pressed, and a connecting rod (243) connecting the second piston (241) and the manual button (242); the elastic member (244) is disposed around the link (243); said manual button (242) being adapted to be pressed to compress said resilient member (244) and to drive said second piston (241) to compress gas within said gas chamber (230); the resilient member (244) is adapted to return to said compressed state upon withdrawal of said depression to return said drive mechanism.

7. The spray device (10) of claim 6, wherein the second piston assembly (240) includes a one-way valve (245) mounted to the second piston (241); the one-way valve (245) is adapted to open towards the gas chamber (230) and is adapted to direct gas outside the gas chamber (230) into the gas chamber (230) at least when the drive mechanism is reset.

8. The spray device (10) of claim 1, wherein the capsule (100) includes a transition chamber (190) between the first reagent chamber (130) and the nozzle (120); the capsule (100) comprises a spout (170) in communication with the second reagent chamber (140); the nozzle tube (170) communicates with the nozzle (120) through the transition cavity (190).

9. The spray device (10) of claim 1, wherein the base (200) includes an electronic control module adapted to electrically connect with the atomizing oscillating piece (180) to control the atomizing oscillating piece (180) to atomize the reagent within the first reagent chamber (130).