CN113880225A - Degradation agent and method for degrading florfenicol in culture wastewater - Google Patents
Degradation agent and method for degrading florfenicol in culture wastewater Download PDFInfo
- Publication number
- CN113880225A CN113880225A CN202111354634.3A CN202111354634A CN113880225A CN 113880225 A CN113880225 A CN 113880225A CN 202111354634 A CN202111354634 A CN 202111354634A CN 113880225 A CN113880225 A CN 113880225A
- Authority
- CN
- China
- Prior art keywords
- florfenicol
- degradation
- potassium ferrate
- degrading
- hydrogen peroxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- AYIRNRDRBQJXIF-NXEZZACHSA-N (-)-Florfenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)C=C1 AYIRNRDRBQJXIF-NXEZZACHSA-N 0.000 title claims abstract description 55
- 229960003760 florfenicol Drugs 0.000 title claims abstract description 54
- 238000006731 degradation reaction Methods 0.000 title claims abstract description 42
- 230000015556 catabolic process Effects 0.000 title claims abstract description 41
- 239000002351 wastewater Substances 0.000 title claims abstract description 29
- 230000000593 degrading effect Effects 0.000 title claims abstract description 16
- 238000000034 method Methods 0.000 title claims abstract description 13
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 46
- UMPKMCDVBZFQOK-UHFFFAOYSA-N potassium;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[K+].[Fe+3] UMPKMCDVBZFQOK-UHFFFAOYSA-N 0.000 claims abstract description 38
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 20
- 238000009360 aquaculture Methods 0.000 claims description 11
- 244000144974 aquaculture Species 0.000 claims description 11
- 230000000694 effects Effects 0.000 abstract description 14
- 229940079593 drug Drugs 0.000 abstract description 7
- 239000003814 drug Substances 0.000 abstract description 7
- 241000894006 Bacteria Species 0.000 abstract description 3
- 238000006243 chemical reaction Methods 0.000 description 12
- 239000000243 solution Substances 0.000 description 12
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 6
- 241000282414 Homo sapiens Species 0.000 description 5
- 230000035484 reaction time Effects 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 3
- 235000019345 sodium thiosulphate Nutrition 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 208000035143 Bacterial infection Diseases 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 229910021538 borax Inorganic materials 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 2
- 235000019799 monosodium phosphate Nutrition 0.000 description 2
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 2
- 229910052938 sodium sulfate Inorganic materials 0.000 description 2
- 235000011152 sodium sulphate Nutrition 0.000 description 2
- 235000010339 sodium tetraborate Nutrition 0.000 description 2
- 239000004328 sodium tetraborate Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 241000606768 Haemophilus influenzae Species 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- XIWMTQIUUWJNRP-UHFFFAOYSA-N amidol Chemical compound NC1=CC=C(O)C(N)=C1 XIWMTQIUUWJNRP-UHFFFAOYSA-N 0.000 description 1
- 229940124350 antibacterial drug Drugs 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 229940047650 haemophilus influenzae Drugs 0.000 description 1
- 231100000304 hepatotoxicity Toxicity 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000007056 liver toxicity Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 238000001471 micro-filtration Methods 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000002352 surface water Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000004065 wastewater treatment Methods 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/72—Treatment of water, waste water, or sewage by oxidation
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/72—Treatment of water, waste water, or sewage by oxidation
- C02F1/722—Oxidation by peroxides
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2101/00—Nature of the contaminant
- C02F2101/30—Organic compounds
- C02F2101/34—Organic compounds containing oxygen
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2101/00—Nature of the contaminant
- C02F2101/30—Organic compounds
- C02F2101/36—Organic compounds containing halogen
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2101/00—Nature of the contaminant
- C02F2101/30—Organic compounds
- C02F2101/38—Organic compounds containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2101/00—Nature of the contaminant
- C02F2101/30—Organic compounds
- C02F2101/40—Organic compounds containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2103/00—Nature of the water, waste water, sewage or sludge to be treated
- C02F2103/20—Nature of the water, waste water, sewage or sludge to be treated from animal husbandry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Hydrology & Water Resources (AREA)
- Engineering & Computer Science (AREA)
- Environmental & Geological Engineering (AREA)
- Water Supply & Treatment (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a degrading agent and a method for degrading florfenicol in culture wastewater. The degrading agent comprises potassium ferrate and hydrogen peroxide; the degradation agent is added into the culture wastewater, and the florfenicol in the culture wastewater can be degraded after standing for 40-50 min. When the degradation agent is used for treating florfenicol in culture wastewater, the degradation agent has the advantages of low cost, easiness in operation, good degradation effect and the like, and avoids the generation of drug-resistant bacteria.
Description
Technical Field
The invention belongs to the field of wastewater treatment, and particularly relates to a degrading agent and a method for degrading florfenicol in aquaculture wastewater.
Background
Florfenicol is also called florfenicol, which is a special amidol broad-spectrum antibacterial drug developed in the late stage of the last eighties. The color is white or off-white, is a crystalline powder, is bitter and odorless, is easily soluble in methanol, and is slightly soluble in water. Can be used for treating bacterial diseases of pig, chicken and aquatic animals, especially bacterial infection of intestinal tract and respiratory system.
A large amount of florfenicol is used for farms every year in China and finally enters culture wastewater along with excrement. The florfenicol residue in the breeding wastewater can cause the immune toxicity and liver toxicity of animals, and simultaneously can induce a plurality of drug-resistant strains coexisting with human and livestock, such as haemophilus influenzae, golden yellow bacillus and the like, to begin to appear and become more serious. Human beings may ingest the florfenicol left in the environment by means of the food chain, and the florfenicol is damaged by direct toxicity and the probability of tolerance of pathogenic bacteria of the human bodies is increased. At present, multiple drug-resistant genes cfr induced by florfenicol can generate drug resistance to five types of drugs, and pose great threat to treatment of human infectious diseases. If the florfenicol-containing aquaculture wastewater is discharged to the ecological environment without special treatment, the florfenicol-containing aquaculture wastewater may enter surface water and underground water environments, and has great harm to the health of animals and human beings. Therefore, how to treat florfenicol in the aquaculture wastewater is very critical.
At present, the treatment methods mainly comprise biological treatment, chlorine disinfection treatment, physical treatment, membrane treatment and ozone treatment, and the treatment methods have the problems of easy generation of drug-resistant bacteria, high economic cost, poor safety, easy blockage of pore diameters and the like. Therefore, the method for degrading florfenicol is very significant.
Disclosure of Invention
In order to solve the defects of the prior art, the inventor provides a degrading agent for degrading florfenicol in aquaculture wastewater through a large amount of researches, and specifically adopts the following technical scheme:
a degrading agent for degrading florfenicol in culture wastewater comprises potassium ferrate and hydrogen peroxide.
In some preferred embodiments, the molar ratio of potassium ferrate to hydrogen peroxide is 1: 0.5-4. Preferably 1: 1.
The inventor finds that florfenicol in the culture wastewater can be effectively degraded by adopting the synergistic cooperation of potassium ferrate and hydrogen peroxide, and the degradation efficiency can reach 80%.
On the basis of the above, the inventor also provides a method for degrading florfenicol in aquaculture wastewater, which comprises the following steps: adding the degradation agent of any one of claims 1 to 3 into the culture wastewater, and standing for 40 to 50 min.
In some preferred implementation cases, after the potassium ferrate in the degradation agent is added to the culture wastewater, the pH value of the culture wastewater is adjusted to 6.5-7.5, and then hydrogen peroxide is added. Preferably, the pH of the aquaculture wastewater is adjusted to 7.
Preferably, the molar ratio of the potassium ferrate in the degradation agent to the florfenicol in the culture wastewater is 40-60: 1. Preferably 45: 1.
The invention has the beneficial effects that: when the degradation agent is used for treating florfenicol in culture wastewater, the degradation agent has the advantages of low cost, easiness in operation, good degradation effect and the like, and avoids the generation of drug-resistant bacteria.
Drawings
FIG. 1 shows a chromatogram of a 75. mu. mol/L florfenicol solution;
FIG. 2 shows a standard curve for a florfenicol solution;
FIG. 3 is a graph showing the effect of potassium ferrate dosage on florfenicol degradation;
FIG. 4 is a graph showing the effect of hydrogen peroxide to potassium ferrate ratio on florfenicol degradation;
FIG. 5 is a graph showing the results of pH effects on florfenicol degradation;
FIG. 6 is a graph showing the results of the effect of reaction time on florfenicol degradation.
Detailed Description
The concept and technical effects of the present invention will be clearly and completely described below in conjunction with the embodiments and the accompanying drawings to fully understand the objects, aspects and effects of the present invention.
The main reagents used in the following examples are shown in Table 1 and the main apparatus is shown in Table 2.
TABLE 1
TABLE 2
Example 1:
(1) preparing a solution:
preparing a florfenicol solution: weighing 0.0537g of florfenicol, and dissolving the florfenicol in a 500mL volumetric flask by using absolute ethyl alcohol to prepare 300 mu mol/L of florfenicol.
Preparing a buffer solution: 1mmol/L borax and 5mmol/L sodium dihydrogen phosphate, and adjusting the pH value to 9.
Preparing potassium ferrate: weighing a certain mass of potassium ferrate, and performing constant volume by using a prepared buffer solution.
Preparing hydrogen peroxide: calculating the concentration of hydrogen peroxide according to the molar ratio of the potassium ferrate to the hydrogen peroxide, weighing the hydrogen peroxide with corresponding mass, and performing constant volume by using pure water.
Preparing sodium thiosulfate: sodium thiosulfate was prepared at a concentration of 0.1mol/L for terminating the reaction after reaching a predetermined time point, and the ratio to the reaction solution was 4: 1.
(2) Drawing a standard curve:
using high performance liquid chromatograph (chromatographic column is S mu nfireC)18Column, mobile phase acetonitrile and pH 4 sodium sulfate solution, flow rate 1.0mL/min, detection wavelength 230nm, using 0.22 μm filter) 300, 75, 37 pairs5, 18.75 and 9.375 mu mol/L of florfenicol, and the obvious absorption peak of the sample at about 220nm can be effectively observed (the chromatogram of 75 mu mol/L is shown in figure 1). A corresponding standard curve was made based on the measured peak areas and the corresponding solution concentrations (as shown in table 3), as shown in figure 2. As can be seen, the linear relation between the concentration of the florfenicol and the peak area within the concentration range of 0-300 mu mol/L is good, and the correlation coefficient>0.999。
TABLE 3
After the sample is detected by the high performance liquid chromatography, the content of the residual florfenicol in the system after the reaction is finished is calculated by using a standard curve, so that the degradation rate can be calculated.
Example 2:
the specific degradation process is as follows:
the reaction is carried out in a 50mL centrifuge tube, 10mL florfenicol solution (300. mu. mol/L) is added into the centrifuge tube, a magnetic stirrer is used for stirring at the rotating speed of 500rpm, potassium ferrate solution prepared by borax and sodium dihydrogen phosphate mixed solution is added while stirring, then the pH of the reaction system is adjusted (adjusted by 0.1mol/L sodium hydroxide and 0.1mol/L hydrochloric acid), hydrogen peroxide is added as an experimental group, purified water with the same volume is added as a control group, after a period of reaction, sampling is carried out, and 1/4 volume of sodium thiosulfate solution (0.1mol/L) is added into the reaction system to stop the reaction.
The sample was vortexed, filtered through a 0.22 μm microfiltration membrane (aqueous system), and then analyzed and detected by a high performance liquid chromatograph. Chromatographic conditions are as follows: the chromatographic column is S mu nfireC18The column was filled with acetonitrile and a solution of sodium sulfate at pH 4, flow rate 1.0mL/min, detection wavelength 230nm, and filtered through a 0.22 μm filter. Specific experimental conditions and results are shown in table 4.
TABLE 4
A is the molar ratio of potassium ferrate to florfenicol; b is the molar ratio of hydrogen peroxide to potassium ferrate; c is pH; d is the reaction time (min).
Wherein the maximum ratio of the molar ratio of the potassium ferrate to the florfenicol is 45:1, and the degradation rate can reach 77.55%; the largest molar ratio of the hydrogen peroxide to the potassium ferrate is 1:1, and the degradation rate can reach 86.62%; the maximum pH value is Ph-7, and the degradation rate reaches 70.84%; the average reaction time is 45min at most, and the degradation rate reaches 73.57%. The most influencing factor of the reaction can be obtained by comparing the range of the difference of the two levels, namely the molar ratio of hydrogen peroxide to potassium ferrate, the molar ratio of potassium ferrate to florfenicol and the least influencing factor of the two levels is the pH value of the reaction system. The optimal level combination of all factors is B3A4D3C3
As can be seen from the table 5 of orthogonal variance analysis, the molar ratio of potassium ferrate to florfenicol and the molar ratio of hydrogen peroxide to potassium ferrate have significant differences, and the results show that the two factors have the greatest influence on the experimental results, and the degradation rate difference between the levels is significant.
TABLE 5
As can be seen from an orthogonal variance analysis table, the molar ratio of potassium ferrate to florfenicol and the molar ratio of hydrogen peroxide to potassium ferrate have obvious differences, and the results show that the two factors have the greatest influence on the experimental results, and the degradation rate difference between the levels is obvious.
(1) Influence of potassium ferrate dosage on florfenicol degradation:
the effect of potassium ferrate dosage on florfenicol degradation is shown in figure 3. When the ratio of the potassium ferrate to the florfenicol is 45:1, the content of the florfenicol drug left after the reaction is the lowest, and the degradation rate can reach 78%. When the proportion is increased to 60:1, the degradation rate can reach 80 percent, and the adding amount of the additive is not in direct proportion to the increase of the degradation rate. In the experiment, the concentration of the florfenicol in the system is 300 mu mol/L, and when the ratio of the potassium ferrate to the florfenicol is 60:1, the potassium ferrate in the system is 18000 mu mol/L, a saturated state is reached, and the excessive potassium ferrate cannot be dissolved.
(2) The influence of the ratio of hydrogen peroxide to potassium ferrate on the degradation of florfenicol:
as can be seen from FIG. 4, when the ratio of hydrogen peroxide to potassium ferrate is 1:1, the degradation effect of the reaction is the best, and the degradation ratio can reach 86%. With the increase of the proportion of hydrogen peroxide to potassium ferrate, the degradation efficiency is firstly increased and then reduced.
(3) Effect of pH on florfenicol degradation: as can be seen from fig. 5, the degradation effect was the best at pH 7.
(4) Effect of reaction time on florfenicol degradation: as can be seen from FIG. 6, the potassium ferrate was most degraded when the reaction time was 45 min.
The above description is only a preferred embodiment of the present invention, and the present invention is not limited to the above embodiment, and the present invention shall fall within the protection scope of the present invention as long as the technical effects of the present invention are achieved by the same means. The invention is capable of other modifications and variations in its technical solution and/or its implementation, within the scope of protection of the invention.
Claims (8)
1. A degrading agent for degrading florfenicol in culture wastewater is characterized by comprising potassium ferrate and hydrogen peroxide.
2. The degradation agent according to claim 1, wherein the molar ratio of potassium ferrate to hydrogen peroxide is 1: 0.5-4.
3. The degradation agent according to claim 2, wherein the molar ratio of potassium ferrate to hydrogen peroxide is 1: 1.
4. A method for degrading florfenicol in aquaculture wastewater is characterized by comprising the following steps: adding the degradation agent of any one of claims 1 to 3 into the culture wastewater, and standing for 40 to 50 min.
5. The method according to claim 4, wherein the potassium ferrate in the degradation agent is added to the aquaculture wastewater, the pH of the aquaculture wastewater is adjusted to 6.5-7.5, and then hydrogen peroxide is added.
6. The method of claim 5, wherein the pH of the aquaculture wastewater is adjusted to 7.
7. The method of claim 4, wherein the molar ratio of potassium ferrate in the degradation agent to florfenicol in the wastewater from the culture is 40-60: 1.
8. The method of claim 7, wherein the molar ratio of potassium ferrate to florfenicol is 45: 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111354634.3A CN113880225A (en) | 2021-11-16 | 2021-11-16 | Degradation agent and method for degrading florfenicol in culture wastewater |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111354634.3A CN113880225A (en) | 2021-11-16 | 2021-11-16 | Degradation agent and method for degrading florfenicol in culture wastewater |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113880225A true CN113880225A (en) | 2022-01-04 |
Family
ID=79017584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111354634.3A Pending CN113880225A (en) | 2021-11-16 | 2021-11-16 | Degradation agent and method for degrading florfenicol in culture wastewater |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113880225A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1430896A (en) * | 2003-01-28 | 2003-07-23 | 王永东 | Combination of disinfectors and its applications used in aquiculture |
| CN103011526A (en) * | 2012-12-23 | 2013-04-03 | 山东新时代药业有限公司 | Method for treating erythromycin thiocyanate wastewater |
| CN106882866A (en) * | 2017-02-24 | 2017-06-23 | 河北科技大学 | The method that hydrogen peroxide synergy ozone heterogeneous catalytic oxidation processes waste water |
| KR20210090758A (en) * | 2020-01-10 | 2021-07-21 | 부경대학교 산학협력단 | Prb-aop linking process apparatus and water treatment method using the same |
-
2021
- 2021-11-16 CN CN202111354634.3A patent/CN113880225A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1430896A (en) * | 2003-01-28 | 2003-07-23 | 王永东 | Combination of disinfectors and its applications used in aquiculture |
| CN103011526A (en) * | 2012-12-23 | 2013-04-03 | 山东新时代药业有限公司 | Method for treating erythromycin thiocyanate wastewater |
| CN106882866A (en) * | 2017-02-24 | 2017-06-23 | 河北科技大学 | The method that hydrogen peroxide synergy ozone heterogeneous catalytic oxidation processes waste water |
| KR20210090758A (en) * | 2020-01-10 | 2021-07-21 | 부경대학교 산학협력단 | Prb-aop linking process apparatus and water treatment method using the same |
Non-Patent Citations (1)
| Title |
|---|
| 仇丽君等: "《高铁酸钾与H2O2联用处理高浓度环丙沙星废水》", 《广州化工》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Zhi et al. | Systematic analysis of occurrence, density and ecological risks of 45 veterinary antibiotics: Focused on family livestock farms in Erhai Lake basin, Yunnan, China | |
| Wei et al. | Effect of different carbon sources on microbial community structure and composition of ex-situ biofloc formation | |
| Gopalakannan et al. | Immunomodulatory effects of dietary intake of chitin, chitosan and levamisole on the immune system of Cyprinus carpio and control of Aeromonas hydrophila infection in ponds | |
| Tang et al. | Rapid in vivo determination of fluoroquinolones in cultured puffer fish (Takifugu obscurus) muscle by solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry | |
| Shirsat et al. | Protective role of biogenic selenium nanoparticles in immunological and oxidative stress generated by enrofloxacin in broiler chicken | |
| CN102249365B (en) | Method for degrading sulfadiazine in water through gamma irradiation | |
| CN1843589A (en) | Bactericide for reverse osmosis membrane and method for preparing the same | |
| KR101881015B1 (en) | Composition for biofloc water purification using fish farm comprising effective microorganisms as effective component and uses thereof | |
| Jassim et al. | Effect of alkaline water and/or magnetic water on some physiological characteristic in broiler chicken | |
| Rehulka et al. | Vibrio cholerae non-O1/non-O139 infection in fish in the Czech Republic. | |
| CN102058821A (en) | Application of tsaoko oil in preparation of medicament for treating bacterial infection diseases | |
| Zhang et al. | Study on florfenicol-contained feeds delivery in Dicentrarchus labrax seawater recirculating and flowing aquaculture systems | |
| Botelho et al. | Veterinary antibiotics in the environment | |
| CN113880225A (en) | Degradation agent and method for degrading florfenicol in culture wastewater | |
| CN101475924A (en) | Rhodococcus strain for degrading 3-nitrotoluene, as well as preparation method and use | |
| CN109126691A (en) | A kind of modification calcite and preparation method thereof for tetracycline in purified water | |
| EP3270706A1 (en) | Archaebacteria in bioactive animal feed, method of making the composition and methods employing the composition | |
| CN102919183B (en) | Method for effectively inhibiting vibrio breeding in shrimp culture | |
| Yang et al. | Effect of carboxymethyl chitosan on the detoxification and biotransformation of paralytic shellfish toxins in oyster Ostrea rivularis | |
| CN105154375A (en) | Microbial inoculant for degrading phenoxy carboxylic acid weedicide residues and preparation method thereof | |
| CN104478030A (en) | Bacteriostatic powdery processing agent for blue-green algae and preparation method thereof | |
| CN108315386B (en) | Desorption agent formula for detecting bacteria attached to body surface of cyclops zooplankton and preparation method thereof | |
| CN102697807B (en) | Application of health-care drinking liquid in preparation of medicines or health-care products for preventing or treating II-type diabetes mellitus, diabetes mellitus and diabetic nephropathy | |
| JP4476349B2 (en) | Method for enhancing immunity of fish | |
| Moyo | Quantitative analysis of selected antibiotic drug residues in honey and manure samples using modern analytical techniques |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20220104 |