CN113876923A - Preparation method of acne liniment - Google Patents

Preparation method of acne liniment Download PDF

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Publication number
CN113876923A
CN113876923A CN202111332872.4A CN202111332872A CN113876923A CN 113876923 A CN113876923 A CN 113876923A CN 202111332872 A CN202111332872 A CN 202111332872A CN 113876923 A CN113876923 A CN 113876923A
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parts
acne
liniment
preparation
glycerol
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CN202111332872.4A
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伊永平
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a preparation method of an acne liniment, which comprises the following steps: (1) pulverizing herba Houttuyniae, flos Lonicerae, folium Mori and rhizoma Zingiberis recens, decocting, and concentrating to 20-30 ml; (2) adding glycerol into the concentrated solution obtained in the step (1); the prepared acne liniment is a pure Chinese medicinal preparation, can radically cure acne, has high cure rate, good treatment effect, difficult recurrence and no toxic or side effect of western medicines, fully utilizes a Chinese medicinal treasure house and a crushing and taking technology, is applied to clinic, has good treatment effect, is easy to be accepted by patients, and has good treatment effect.

Description

Preparation method of acne liniment
Technical Field
The invention relates to the technical field of pharmacy, in particular to a preparation method of an acne liniment.
Background
Acne is commonly called whelk, acne and pimple, and the ancient Chinese medical science refers to face sore and acne. Acne symptoms: inflammatory papules, pustules, nodules and nodules, inflammatory scar masses and sinuses, and after inflammatory lesions subside, pigmentation, persistent erythema, depressed or hypertrophic scars often remain. Is a common and frequently encountered disease in dermatology, and the disease frequently recurs. Adolescent men have 95% and women have 85% of acne of different degrees. So it is called whelk.
Acne is a chronic skin disease occurring in hair follicle sebaceous glands, is frequently generated in face, neck, chest and back and other parts rich in sebaceous glands, and has the main clinical manifestations of blackhead with thorns, white head acne, inflammatory papules, pustules, nodules and cysts, easy formation of pigmentation, large pores and even scar-like damage, influence on beauty treatment, severe patients can cause disfigurement, great psychological pressure and mental pain are caused to young people, and early-appearing and early-curing of the disease is very important. Timely and standard treatment can avoid or reduce skin damage.
Acne is closely related to factors such as hyperseborrhea, blockage of pilosebaceous ducts, bacterial infection and inflammatory reaction. After puberty, the level of androgens, particularly testosterone, in the human body rapidly rises, the development of cortical glands is promoted, and a large amount of sebum is produced. Meanwhile, abnormal secretion of the pilosebaceous canal causes blockage of the canal, sebum discharge obstruction and formation of a keratotic plug, namely, comedo. A number of microorganisms in the hair follicle, particularly propionibacterium acnes, multiply in numbers, and esterases produced by propionibacterium acnes break down sebum, producing free fatty acids, while chemotactic inflammatory cells and mediators, ultimately inducing and exacerbating inflammation.
Western medicines such as clindamycin and the like are often applied for external use, and oral antibiotics and tretinoin are often used for treatment, so that the effect is poor, and drug resistance and side effects are caused after long-term application.
Therefore, a preparation method of the acne liniment is needed, which can solve the problem that the medicine for treating acne obtained by the existing method has poor treatment effect.
Disclosure of Invention
The prepared acne liniment is a pure Chinese medicinal preparation, fundamentally cures acne, has high cure rate, good treatment effect, is not easy to relapse, has no toxic or side effect of western medicines, fully utilizes Chinese medicine treasury and crushing technology, is applied to clinic, has good curative effect, is easy to be accepted by patients, and receives good treatment effect.
In order to achieve the purpose, the invention provides the following scheme:
the invention provides a preparation method of an acne liniment, which comprises the following steps:
(1) pulverizing herba Houttuyniae, flos Lonicerae, folium Mori and rhizoma Zingiberis recens, decocting, and concentrating to 20-30 ml;
(2) adding glycerol into the concentrated solution in the step (1).
Preferably, the method comprises the following steps:
(1) pulverizing 100 parts of houttuynia cordata, 100 parts of honeysuckle, 100 parts of mulberry leaves and 100 parts of ginger, decocting and concentrating to 25 ml;
(2) 150 parts of glycerol is added into the concentrated solution in the step (1).
Preferably, the method comprises the following steps:
(1) 80 parts of houttuynia cordata, 130 parts of honeysuckle, 120 parts of mulberry leaves and 85 parts of ginger are crushed, decocted and concentrated to 30 ml;
(2) 160 parts of glycerol is added into the concentrated solution in the step (1).
Preferably, the method comprises the following steps:
(1) pulverizing 120 parts of houttuynia cordata, 80 parts of honeysuckle, 70 parts of mulberry leaves and 115 parts of ginger, decocting and concentrating to 20 ml;
(2) 130 parts of glycerol is added into the concentrated solution in the step (1).
Preferably, the water content of the glycerol is 20 wt%.
Compared with the prior art, the invention has the following beneficial technical effects:
the acne liniment prepared by the preparation method provided by the invention is a pure traditional Chinese medicine preparation, can radically cure acne, has high cure rate and good treatment effect, is not easy to relapse, has no toxic or side effect of western medicines, fully utilizes the Chinese medicine treasury and the smashing and taking technology, has good curative effect when being applied to clinic, is easy to be accepted by patients, and has good treatment effect.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention aims to provide a preparation method of an acne liniment, which aims to solve the problem that the medicine for treating acne obtained by the existing method has poor treatment effect.
The present invention will be described in further detail with reference to specific embodiments in order to make the above objects, features and advantages more apparent and understandable.
Example 1:
the embodiment provides a preparation method of an acne liniment, which comprises the following raw materials in parts by mass:
100 parts of houttuynia cordata, 100 parts of honeysuckle, 100 parts of mulberry leaves, 100 parts of ginger and 150 parts of glycerol.
Wherein the water content of the glycerol is 20 wt%.
The preparation method comprises the following specific steps:
(1) pulverizing 100 parts of houttuynia cordata, 100 parts of honeysuckle, 100 parts of mulberry leaves and 100 parts of ginger, decocting and concentrating to 25 ml;
(2) 150 parts of glycerol is added into the concentrated solution in the step (1).
Example 2:
the embodiment provides another preparation method of an acne liniment, which comprises the following raw materials in parts by mass:
80 parts of houttuynia cordata, 130 parts of honeysuckle, 120 parts of mulberry leaves, 85 parts of ginger and 160 parts of glycerol.
Wherein the water content of the glycerol is 20 wt%.
The preparation method comprises the following specific steps:
(1) 80 parts of houttuynia cordata, 130 parts of honeysuckle, 120 parts of mulberry leaves and 85 parts of ginger are crushed, decocted and concentrated to 30 ml;
(2) 160 parts of glycerol is added into the concentrated solution in the step (1).
Example 3:
the embodiment provides another preparation method of an acne liniment, which comprises the following raw materials in parts by mass:
120 parts of houttuynia cordata, 80 parts of honeysuckle, 70 parts of mulberry leaves, 115 parts of ginger and 130 parts of glycerol.
Wherein the water content of the glycerol is 20 wt%.
The preparation method comprises the following specific steps:
(1) pulverizing 120 parts of houttuynia cordata, 80 parts of honeysuckle, 70 parts of mulberry leaves and 115 parts of ginger, decocting and concentrating to 20 ml;
(2) 130 parts of glycerol is added into the concentrated solution in the step (1).
The mechanism of the medicine of the acne liniment prepared by the preparation method of the acne liniment provided by the invention is as follows:
houttuynia cordata: resisting pathogenic microorganism, inhibiting bacteria such as Staphylococcus aureus, promoting urination, enhancing immunity, and resisting tumor
Honeysuckle flower: disperse wind-heat, clear blood toxin, enhance immunity, resist inflammation and clear heat.
Mulberry leaf: dispelling wind and heat, relieving inflammation, caring skin, clearing liver and lung, improving eyesight, cooling blood, and stopping bleeding
Ginger: relieving exterior syndrome, dispelling pathogenic wind and cold, and relieving inflammation.
Glycerol: the water content of 20% glycerin can whiten and moisturize the skin and keep the skin moist and not dry.
The efficacy is as follows: clearing away heat and toxic material, dispersing wind-cold, relieving exterior syndrome and beautifying face
The main treatment is as follows: various types of acne are particularly suitable for early facial lesions, and the prevention, the health care and the early treatment of the acne are realized.
Treatment criteria were:
and (3) healing: the skin color of the initial patient returns to normal and the acne disappears.
The basic cure is as follows: acne disappears, and a little bean mark exists after skin damage of a long-term patient.
And (4) invalidation: no effect, the disease condition is as before.
The treatment effect is as follows: the clinical application treats 120 patients, 60 men and 60 women, and the clinical treatment lasts for 10-30 days, the cure rate is 95%, the basic cure rate is 5%, the effect is not effective (no), and the medicine has no side effect on the patients.
Several specific examples are listed below:
case 1
Duqi, female 36 years old, facial acne for 2 years, pimple, redness, rising skin, seriously affecting beauty, patients suffering from insanity, the treatment with the formula can be cured in 1 month.
Case 2
The symptoms of certain Yang, female, 19 years old, students and facial acne which are afraid of seeing and unwilling to see are basically disappeared by treating for 15 days with the medicine, and the symptoms are completely disappeared by strengthening external application for half a year later.
Case 3
The formula is externally applied on a cotton stick for 7 days, so that the acne is obviously reduced, the redness part is reduced, and no other discomfort is caused. After the application, several cotton sticks are applied to the affected part for 5 minutes to increase the drug absorption and local telangiectasia, which is beneficial to rehabilitation. After 30 days of treatment, the patient recovers.
The principle and the implementation mode of the invention are explained by applying specific examples, and the description of the above examples is only used for helping understanding the method and the core idea of the invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In summary, this summary should not be construed to limit the present invention.

Claims (5)

1. The preparation method of the acne liniment is characterized by comprising the following steps: the method comprises the following steps:
(1) pulverizing herba Houttuyniae, flos Lonicerae, folium Mori and rhizoma Zingiberis recens, decocting, and concentrating to 20-30 ml;
(2) adding glycerol into the concentrated solution in the step (1).
2. The method for preparing the acne liniment according to claim 1, characterized in that: the method comprises the following steps:
(1) pulverizing 100 parts of houttuynia cordata, 100 parts of honeysuckle, 100 parts of mulberry leaves and 100 parts of ginger, decocting and concentrating to 25 ml;
(2) 150 parts of glycerol is added into the concentrated solution in the step (1).
3. The method for preparing the acne liniment according to claim 1, characterized in that: the method comprises the following steps:
(1) 80 parts of houttuynia cordata, 130 parts of honeysuckle, 120 parts of mulberry leaves and 85 parts of ginger are crushed, decocted and concentrated to 30 ml;
(2) 160 parts of glycerol is added into the concentrated solution in the step (1).
4. The method for preparing the acne liniment according to claim 1, characterized in that: the method comprises the following steps:
(1) pulverizing 120 parts of houttuynia cordata, 80 parts of honeysuckle, 70 parts of mulberry leaves and 115 parts of ginger, decocting and concentrating to 20 ml;
(2) 130 parts of glycerol is added into the concentrated solution in the step (1).
5. The method for preparing the acne liniment according to any one of claims 1 to 4, characterized in that: the water content of the glycerol was 20 wt%.
CN202111332872.4A 2017-06-16 2017-06-16 Preparation method of acne liniment Pending CN113876923A (en)

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CN201710458858.6A CN107184939A (en) 2017-06-16 2017-06-16 Acne embrocates cream
CN202111332872.4A CN113876923A (en) 2017-06-16 2017-06-16 Preparation method of acne liniment

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CN202111332872.4A Pending CN113876923A (en) 2017-06-16 2017-06-16 Preparation method of acne liniment

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104027505A (en) * 2014-06-26 2014-09-10 马健 Method for preparing traditional Chinese medicine facial mask powder for treating pimple

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104027505A (en) * 2014-06-26 2014-09-10 马健 Method for preparing traditional Chinese medicine facial mask powder for treating pimple

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吕选民等: "柴草瓜果篇 第五讲 桑叶", 《中国乡村医药》 *

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Application publication date: 20220104