CN113842435A - Traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy - Google Patents
Traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine external application agent for treating local edema after cancer radiotherapy and chemotherapy. The invention provides a traditional Chinese medicine external application agent, which comprises borneol, dragon's blood, natural indigo, frankincense, myrrh, mirabilite, radix ranunculi ternati, fructus akebiae, angelica, rhizoma alismatis, poria cocos, semen coicis and yellow wine, solves the problem of local edema after radiotherapy and chemotherapy of cancer, can effectively reduce local edema of patients, and has the advantages of high safety, cure rate and effective rate, obvious clinical effect, simplicity, convenience and cheapness.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy.
Background
The local edema after the radiotherapy and chemotherapy of cancer is one of the common complications after the radiotherapy and chemotherapy of tumor, and belongs to the category of edema in the traditional Chinese medicine, and can also be called as 'water-gas disease' or 'excessive fluid retention'.
The traditional Chinese medicine considers that local edema after tumor radiotherapy and chemotherapy is mostly due to deficiency and excess, qi circulation leads to blood circulation, qi and blood circulation is not smooth, and water flows subcutaneously to form edema. The "Nei Jing" (the Nei Jing) about the pathogenesis of edema mainly highlights the concept that the function of zang-fu organs is disordered to cause the depression of yang-qi, dysfunction of qi in transformation, blood vessel obstruction and water accumulation as edema, and especially attaches importance to the important role of lung and kidney in the onset of edema. Su Wen & hydrothermal acupoint theory, cloud states that the kidney is most yin and most yin is full of water; lung is also yin-deficient and winter is also meridian deficient. Therefore, it is also accumulated in the kidney and the lung, emphasizing the important function of the lung and kidney on water metabolism, and the dysfunction is the important mechanism of edema. The article further discusses that the kidney, stomach and door were also closed unfavorably, so that water was collected and the like. The fluid flows up and down the skin, so it is accompanied by swelling. The patients with swelling also get sick due to water accumulation. The original qi is damaged by radiotherapy, so that qi stagnation and blood fatigue are caused, and edema and blood fatigue are closely related after radiotherapy and chemotherapy of tumors. Edema after tumor radiotherapy and chemotherapy can also be caused by yang deficiency and water retention, phlegm dampness and fatigue, after radiotherapy, heat toxin is exuberant, body fluid is damaged, qi and blood and spleen and stomach function are damaged, vein obstruction, fatigue, blood, phlegm dampness and stagnation form deficiency and excess mixed lymphedema.
Clinically, the treatment of local edema after cancer radiotherapy and chemotherapy is by massage, microwave, elastic bandage and other methods, but the curative effect is not good enough. The traditional Chinese medicine has great advantages in treating local edema after cancer radiotherapy and chemotherapy, the traditional Chinese medicine can enable the efficacy of the medicine to quickly permeate the skin to directly reach the affected part by virtue of heat after hot compress, and various Chinese herbal medicines have the effects of diminishing inflammation, relieving pain, promoting blood circulation, removing blood stasis, softening hardness and dissipating stagnation together, so that the edema is easier to absorb and recover. The traditional Chinese medicine external application also avoids the stimulation of the medicine to the gastric mucosa. Has the advantages of convenience, economy, no pain, small side effect and high patient compliance.
Disclosure of Invention
Aiming at the problems in the prior art, the technical problems to be solved by the invention are as follows: clinically, the method of massage, microwave and elastic bandage is adopted to have poor treatment effect on the local edema after the radiotherapy and chemotherapy of cancer.
The technical scheme adopted by the invention for solving the technical problems is as follows: the invention provides a traditional Chinese medicine dressing for treating local edema after cancer chemoradiotherapy, which comprises the following components in parts by weight:
the preparation method of the traditional Chinese medicine dressing for treating lymphedema comprises the following steps: grinding the above medicines into 80-100 mesh powder according to formula amount, adding yellow wine, wherein the weight ratio of yellow wine to traditional Chinese medicine components is 1:20, and blending into paste.
The traditional Chinese medicine dressing disclosed by the invention has the following effects of the traditional Chinese medicine components:
borneol: pungent, bitter and slightly cold in nature. It enters heart, spleen and lung meridians. Has effects of inducing resuscitation, refreshing mind, clearing heat and relieving pain.
Dragon's blood: mild in nature, sweet and salty in flavor. It enters heart and liver meridians. Has effects in dispelling blood stasis, relieving pain, stopping bleeding, and promoting granulation.
Indigo naturalis: salty and cold. It enters liver meridian. Has the functions of clearing away heat and toxic material, cooling blood, eliminating spot, purging fire and arresting convulsion.
Frankincense: pungent, bitter and warm. It enters heart, liver and spleen meridians. Has effects in promoting blood circulation, activating qi-flowing, relieving pain, eliminating swelling, and promoting granulation.
Myrrh: pungent and bitter in flavor and mild in nature. It enters heart, liver and spleen meridians. Has the functions of eliminating blood stasis, relieving pain, eliminating swelling and promoting granulation.
Mirabilite: salty, bitter and cold in nature. It enters stomach and large intestine meridians. Has the effects of relaxing bowels with purgative, moistening dryness, softening hard masses, clearing pathogenic fire and relieving swelling.
Radix ranunculi ternati: sweet, pungent and warm. Neutral in nature, entering liver and lung meridians. Has the functions of detoxification; resolve phlegm and dissipate nodulation.
Predictor: bitter and cold. It enters liver, gallbladder, stomach and bladder meridians. Soothing liver, regulating qi, promoting blood circulation, relieving pain, dispersing pathogen accumulation, and inducing diuresis.
Chinese angelica: sweet, pungent and warm. It enters liver, heart and spleen meridians. Enriching the blood; promoting blood circulation; regulating menstruation and relieving pain; moistening dryness and smoothing intestine.
Rhizoma alismatis: sweet in nature and cold in nature. It enters kidney and bladder meridians. Has effects of promoting diuresis, eliminating dampness, and clearing heat.
Tuckahoe, poria cocos: sweet and bland in flavor and mild in nature. It enters heart, lung, spleen and kidney meridians. Induce diuresis and drain dampness, invigorate spleen and calm heart.
Coix seed: sweet, bland and cool in nature. It enters spleen, stomach and lung meridians. Has effects of promoting diuresis, eliminating dampness, invigorating spleen, eliminating arthralgia, clearing heat, and expelling pus.
The invention has the beneficial effects that:
(1) the invention finally obtains a dressing which is more effective for treating the local edema after the radiotherapy and chemotherapy of the cancer through continuous optimization and adjustment on the basis of the original external application prescription, and the patient has better edema resolution effect after the external application treatment;
(2) the traditional Chinese medicine dressing has more remarkable effect on treating local edema after cancer radiotherapy and chemotherapy by combining with microwave thermotherapy, and the edema can be removed more quickly, so that the pain of a patient can be relieved better;
(3) the traditional Chinese medicine dressing can achieve satisfactory curative effect on treating local edema after radiotherapy and chemotherapy of cancer by combining microwave thermotherapy, has the characteristics of simple operation, no adverse reaction, easy acceptance by patients, relatively low treatment cost and the like, can effectively control the medical cost, and reduces the economic burden of the patients.
Detailed Description
The present invention will now be described in further detail with reference to examples.
Example 1
The traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy comprises the following components in parts by weight:
example 2
The traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy comprises the following components in parts by weight:
example 3
The traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy comprises the following components in parts by weight:
example 4
The traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy comprises the following components in parts by weight:
example 5
The traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy comprises the following components in parts by weight:
comparative example 1 differs from example 1 in that: comparative example 1 also includes peach kernel and safflower.
Comparative example 2 differs from example 1 in that: in comparative example 2, the poria was replaced with grifola.
Comparative example 3 differs from example 1 in that: comparative example 3 contained no mastic.
Comparative example 4 differs from example 1 in that: comparative example 4 contained no myrrh.
Comparative example 5 differs from example 1 in that: comparative example 5 contained no coix seed.
Comparative example 6 differs from example 1 in that: comparative example 6 contained no frankincense, myrrh and coix seed.
The traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy is obtained according to the following steps in the above embodiments 1-5 and comparative examples 1-6, and the specific steps are as follows:
(1) grinding the medicines into powder of 80-100 meshes according to the formula amount, adding yellow wine, and blending into paste, wherein the weight ratio of the yellow wine to the traditional Chinese medicine components is 1: 20.
The Chinese medicinal dressings obtained in examples 1 to 5 of the present invention and comparative examples 1 to 6 were applied to the affected part of a patient, and then, the medicine was covered with gauze, and the gauze was fixed with an adhesive tape.
The therapeutic effects of the dressing of the present invention obtained in the above examples 1 to 5 and comparative examples 1 to 6 were evaluated in the following manner:
general data extraction 240 female patients aged 40-70 years after radiotherapy and chemotherapy of breast cancer in the period of 1 month to 2021 month in 2020, wherein the patients all had left upper limb edema, and were classified into a first treatment group (using the traditional Chinese medicine dressing obtained in example 1), a second treatment group (using the traditional Chinese medicine dressing obtained in example 2), a third treatment group (using the traditional Chinese medicine dressing obtained in example 3), a fourth treatment group (using the traditional Chinese medicine dressing obtained in example 4), and a fifth treatment group (using the traditional Chinese medicine dressing obtained in example 5) according to the difference in age; accordingly, the control groups were divided into a first control group, a second control group, a third control group, a fourth control group, a fifth control group, and a sixth control group in the order of using the traditional Chinese medicine dressings obtained in comparative examples 1 to 6. The age, disease course and disease condition of the patients in the control group and the patients in the first treatment group are not significantly different (P is more than 0.05) through statistical treatment, and the patients in the control group and the patients in the first treatment group have comparability.
The treatment group and the control group both adopt a method of combining external application of traditional Chinese medicine and microwave thermotherapy. The traditional Chinese medicine dressing is smeared on an affected part of a patient, then gauze covers the medicine, the gauze is fixed by using an adhesive tape, then a Nuowan N-9001 microwave tumor thermotherapy instrument is used for carrying out thermotherapy treatment, the affected part of the patient is used as a target area of the thermotherapy, the output power is adjusted to be 40-70W, the frequency is 915MHZ, the skin temperature is maintained between 41 ℃ and 42 ℃, and the treatment is continued for 60min for 1 time/d.
After treatment, clinical manifestations in the treated and control groups are shown in table 1:
TABLE 1
The blank group and the first treatment group refer to the application of the Chinese medicinal dressing obtained in example 1 to the affected part of 20 patients, covering the medicine with gauze, and fixing the gauze with adhesive tape, during which microwave-assisted treatment is not combined.
In light of the foregoing description of the preferred embodiment of the present invention, many modifications and variations will be apparent to those skilled in the art without departing from the spirit and scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.
Claims (3)
1. The traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy is characterized by comprising the following components in parts by weight:
15-30 parts of borneol
20-30 parts of dragon's blood
20-30 parts of indigo naturalis
20-30 parts of frankincense
15-30 parts of myrrh
40-60 parts of mirabilite
25-40 parts of radix ranunculi ternati
25-40 parts of fructus akebiae
30-40 parts of angelica
10-20 parts of rhizoma alismatis
20-40 parts of poria cocos
30-60 parts of coix seeds.
2. The traditional Chinese medicine dressing for treating local edema after cancer chemoradiotherapy according to claim 1, which comprises the following components:
30 portions of borneol
30 portions of dragon's blood
Indigo naturalis 30 parts
Frankincense 30 parts
30 portions of myrrh
Mirabilite 60 parts
40 parts of radix ranunculi ternati
Foreseeing 40 portions of fructus akebiae
40 portions of angelica
20 portions of alisma orientale
40 portions of tuckahoe
60 parts of coix seeds.
3. The traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy according to any one of claims 1-2, characterized in that the preparation method is as follows: grinding the traditional Chinese medicine components into powder according to the formula amount, adding yellow wine, wherein the weight ratio of the yellow wine to the traditional Chinese medicine components is 1:20, and blending into paste to obtain the traditional Chinese medicine composition.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110822835.5A CN113842435A (en) | 2021-07-21 | 2021-07-21 | Traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110822835.5A CN113842435A (en) | 2021-07-21 | 2021-07-21 | Traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy |
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| CN113842435A true CN113842435A (en) | 2021-12-28 |
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| CN202110822835.5A Pending CN113842435A (en) | 2021-07-21 | 2021-07-21 | Traditional Chinese medicine dressing for treating local edema after cancer radiotherapy and chemotherapy |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1144664A (en) * | 1995-09-04 | 1997-03-12 | 付耀华 | Fragrant health-care bra medicine pad |
| CN203220605U (en) * | 2013-03-04 | 2013-10-02 | 赵性荣 | Quick-acting tumor pain relieving bag |
| CN105641346A (en) * | 2016-01-30 | 2016-06-08 | 吴谋军 | Transdermal analgesic free of toxic and side effects and preparation method thereof |
-
2021
- 2021-07-21 CN CN202110822835.5A patent/CN113842435A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1144664A (en) * | 1995-09-04 | 1997-03-12 | 付耀华 | Fragrant health-care bra medicine pad |
| CN203220605U (en) * | 2013-03-04 | 2013-10-02 | 赵性荣 | Quick-acting tumor pain relieving bag |
| CN105641346A (en) * | 2016-01-30 | 2016-06-08 | 吴谋军 | Transdermal analgesic free of toxic and side effects and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 张咏梅等: "清热消肿汤为主治疗乳腺癌术后上肢淋巴水肿观察", 《浙江中医杂志》 * |
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