CN111773300A - Plaster for promoting blood circulation, relieving pain and setting fracture and preparation method thereof - Google Patents

Plaster for promoting blood circulation, relieving pain and setting fracture and preparation method thereof Download PDF

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Publication number
CN111773300A
CN111773300A CN202010757646.XA CN202010757646A CN111773300A CN 111773300 A CN111773300 A CN 111773300A CN 202010757646 A CN202010757646 A CN 202010757646A CN 111773300 A CN111773300 A CN 111773300A
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parts
plaster
blood circulation
bone
promoting blood
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梁高峰
李洪超
杜景霞
冯书营
景爱华
王浩洁
朱梦玺
徐娟娟
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Henan University of Science and Technology
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Henan University of Science and Technology
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Priority to CN202010757646.XA priority Critical patent/CN111773300A/en
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
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    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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Abstract

The invention discloses a plaster for promoting blood circulation, relieving pain and setting fracture, which comprises the following raw materials of 30 parts of frankincense, 30 parts of eupolyphaga, 25 parts of myrrh, 30 parts of buffalo hide, 40 parts of keel, 25 parts of borneol, 25 parts of sialon bone, 25 parts of dragon's blood flower, 25 parts of garden balsam stem, 30 parts of chunling root bark, 25 parts of artificial musk, 25 parts of saffron, 25 parts of pseudo-ginseng, 25 parts of dragon's blood, 0.5 part of nux vomica, 25 parts of pig nail, 25 parts of angelica, 40 parts of ligusticum chuanxiong hort, 40 parts of native copper, 40 parts of drynaria rhizome, 40 parts of liquorice, 25 parts of minium and 1200 parts. The plaster is prepared by heating, can obviously shorten the healing time of patients with fracture and ligament injury, has quick response, small wound, low cost and short treatment time period, and can be accepted by the public.

Description

Plaster for promoting blood circulation, relieving pain and setting fracture and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a plaster for promoting blood circulation, relieving pain and setting a broken bone and a preparation method thereof.
Background
Fracture refers to the continuous complete or partial breakdown of bone structure. There are three main conditions in which fractures occur: direct violence, indirect violence, cumulative strain, localized deformity, abnormal activity, grating bone or sensation of grating bone. Whether the fracture is connected with the outside can be classified into closed fracture and open fracture, and symptoms such as fever and shock can appear on the whole body. At present, for patients with closed fracture and no displacement, splints or plaster are mostly adopted for external fixation, and bone-setting medicines are orally taken; for patients with serious displacement of fracture ends, the operation treatment and the rest and rest in bed are needed, the fracture healing is slow, delayed healing and bone nonunion can occur to some patients after the operation, the life and the study of the patients are seriously influenced, and meanwhile, the serious economic burden is brought to the patients. At present, most of bone-knitting plasters on the market are produced in batches, and due to the fact that the dosage of a single plaster is insufficient, the application time is short, and the effect on repairing fractures and ligament injuries is not ideal.
Disclosure of Invention
The invention aims to make up the defects of the prior art and provides a plaster for promoting blood circulation, relieving pain and setting a broken bone and a preparation method thereof.
In order to achieve the purpose, the invention provides the following technical scheme:
the plaster comprises the following raw materials in parts by mass:
25-35 parts of frankincense, 25-35 parts of eupolyphaga, 20-30 parts of myrrh, 35-45 parts of keel, 20-30 parts of borneol, 20-30 parts of sialon bone, 20-30 parts of dragon's blood flower, 20-30 parts of garden balsam stem, 25-35 parts of chunshige root bark, 20-30 parts of artificial musk, 20-30 parts of saffron, 20-30 parts of pseudo-ginseng, 20-30 parts of dragon's blood, 0.2-0.5 part of nux vomica, 20-30 parts of pig nail, 20-30 parts of angelica, 35-45 parts of ligusticum chuanxiong hort, 35-45 parts of native copper, 35-45 parts of rhizoma drynariae, 35-45 parts of liquorice, 20-30 parts of Guangdan and 1300 parts of sesame oil 1100.
Preferably, the plaster raw materials also comprise 25-35 parts of buffalo hide.
Preferably, the plaster raw materials comprise the following raw materials in parts by mass:
30 parts of frankincense, 30 parts of eupolyphaga, 25 parts of myrrh, 40 parts of keel, 25 parts of borneol, 25 parts of sialon bone, 25 parts of dragon's blood flower, 25 parts of garden balsam stem, 30 parts of root bark of chun rhizomes, 25 parts of artificial musk, 25 parts of saffron crocus, 25 parts of pseudo-ginseng, 25 parts of dragon's blood, 0.5 part of nux vomica, 25 parts of pig nail, 25 parts of angelica, 40 parts of ligusticum chuanxiong hort, 40 parts of native copper, 40 parts of rhizoma drynariae, 40 parts of liquorice, 25 parts of minium and 1200 parts of sesame oil.
A preparation method of a plaster for promoting blood circulation, relieving pain and setting a fracture comprises the following steps:
(1) weighing the required raw materials;
(2) cutting the frankincense, the dried body of ground beetle, the myrrh, the buffalo hide, the keel, the borneol, the sialon bone, the dragon's blood flower, the garden balsam stem, the root bark of chun white, the artificial musk, the saffron, the pseudo-ginseng, the dragon's blood, the nux vomica, the pig nail, the Chinese angelica, the ligusticum chuanxiong hort, the native copper, the rhizoma drynariae and the liquorice which are weighed in the step (1) into small pieces respectively;
(3) soaking the cut traditional Chinese medicines in the step (2) in sesame oil;
(4) fishing out the traditional Chinese medicine soaked in the sesame oil in the step (3) and draining the oil;
(5) pouring sesame oil soaked with the traditional Chinese medicines into a container for preheating, adding the traditional Chinese medicines with the dry oil content controlled into the container in batches, heating and decocting the traditional Chinese medicines, stirring continuously in the decocting process, fishing out dregs after decocting for a period of time, and continuing to decoct;
(6) after the medicinal oil is decocted in the step (5), adding minium with small fire, and continuing decocting until the plaster is decocted;
(7) and (3) after the plaster is decocted, annealing treatment is carried out to obtain the plaster for promoting blood circulation, relieving pain and setting bone.
Preferably, the soaking time in the step (3) is 24 hours.
Preferably, the preheating temperature in the step (5) is 80 ℃; the heating temperature is 200-300 ℃; and after the decoction time is 5-6 hours, fishing out the decoction dregs, and continuing to decoct.
Preferably, the method for judging the cooking of the medicinal oil in the step (6) comprises the following steps: taking out a drop of medicinal oil, and dripping into water of 8-10 deg.C, wherein if the medicinal oil is aggregated in water to form a group, it indicates that the medicinal oil has been decocted;
the method for judging whether the plaster is decocted in the step (6) comprises the following steps: stirring while adding Plumbum Preparatium, and when the smoke changes from green smoke to white smoke, it indicates that the plaster is decocted.
Preferably, the annealing treatment method in the step (7) comprises the following steps: pouring the decocted plaster into 8-10 deg.C water, stirring to make the plaster agglomerate, soaking for 3-7 days to remove fire toxin, and replacing clear water once every 24 hr.
Preferably, the use method of the bone-knitting plaster comprises the following steps: softening the plaster, then uniformly applying on cotton cloth, and applying on affected part.
The pharmacological actions of the traditional Chinese medicine components are as follows:
frankincense: nature and taste: pungent, bitter and warm; meridian tropism: heart, liver and spleen meridians entered; the efficacy is as follows: promote blood circulation, move qi and alleviate pain, resolve swelling and promote tissue regeneration.
B, ground beetle: nature and taste: salty and cold; has little toxicity; meridian tropism: entering liver meridian; the functions are as follows: removing blood stasis, eliminating abdominal mass, treating fracture, removing blood stasis and relieving pain; can be used for treating fracture of tendons and bones, amenorrhea due to blood stasis, and abdominal mass.
Myrrh: nature and taste: mild in nature, pungent and bitter in flavor; meridian tropism: heart, liver and spleen meridians entered; the efficacy is as follows: dispel stasis, relieve pain, resolve swelling and promote tissue regeneration.
Buffalo hide: nature and taste: salty and flat; meridian tropism: entering the lung and bladder meridians; the efficacy is as follows: promote granulation, heal wound and stop bleeding, and can be used as a substitute for elephant skin.
Keel: nature and taste: mild in nature, astringent and sweet in taste; meridian tropism: the channels of heart, liver, kidney and large intestine; the efficacy is as follows: induce sedation and tranquilization, pacify liver and subdue yang, induce astringency and astringe.
Borneol: nature and taste: slightly cold in nature, pungent and bitter in flavor; meridian tropism: heart, liver and lung meridians entered; the efficacy is as follows: has effects of inducing resuscitation, refreshing mind, clearing away heat, removing toxic substances, improving eyesight, and eliminating nebula.
The bone of the sialon: sialon, a zokor, also known as zokor and geoshes, belongs to mammals of the order rodentia, the family cancridae and the subfamily zokorea, is slightly warm in nature, is pungent and salty in taste, and enters the liver; the kidney channel has the functions of expelling wind and removing dampness, dispelling cold, relaxing tendons and activating collaterals, strengthening muscles and bones and the like.
Dragon's blood: nature and taste: mild in nature, sweet and salty in taste; meridian tropism: heart and liver meridian entered; the efficacy is as follows: promoting blood circulation, relieving pain, removing blood stasis, stopping bleeding, healing sore, and promoting granulation.
Garden balsam stem: nature and taste: warm in nature, sweet and pungent in flavor; meridian tropism: entering lung and liver meridians; the efficacy is as follows: dispelling pathogenic wind and removing dampness, relieving rigidity of muscles and activating collaterals, promoting blood circulation and relieving pain, removing toxic substance and eliminating rash.
Root bark of spring rhizome: nature and taste: cold in nature, bitter and astringent in taste; meridian tropism: entering large intestine, liver and stomach meridians; the efficacy is as follows: clear heat and dry dampness, astringe and stop leucorrhea, check diarrhea, stop bleeding.
Artificial musk: nature and taste: warm in nature and pungent in flavor; meridian tropism: heart and spleen meridians entered; the efficacy is as follows: inducing resuscitation and refreshing mind, promoting blood circulation and dredging channels, and relieving swelling and pain.
Saffron: nature and taste: mild in nature and sweet in taste; the efficacy is as follows: promoting blood circulation, removing blood stasis, resolving stagnation, and relieving pain; can be used for treating pain due to blood stasis and traumatic injury.
Pseudo-ginseng: notoginseng, nature and taste: warm in nature, sweet and slightly bitter in taste; meridian tropism: entering liver and stomach meridians; the efficacy is as follows: has the effects of stopping bleeding, removing blood stasis, diminishing inflammation, relieving pain and nourishing, and is a main medicine for treating traumatic injury.
Dragon's blood: nature and taste: mild in nature, sweet, pungent and salty in flavor; meridian tropism: entering lung, spleen and kidney meridians; the efficacy is as follows: promoting blood circulation, removing blood stasis, relieving pain, stopping bleeding, healing wound, and promoting granulation. Can be used for treating traumatic injury, pain due to blood stasis, traumatic hemorrhage, and intractable abscess.
Nux vomica: nature and taste: warm in nature and bitter in taste; has strong toxicity; meridian tropism: entering liver and spleen meridians; the efficacy is as follows: can be used for treating traumatic blood stasis swelling pain, carbuncle, cellulitis, and swelling pain.
Pig nail: nature and taste: salty taste, slightly cold nature; meridian tropism: entering stomach and large intestine meridians; the efficacy is as follows: resolving phlegm, relieving asthma, removing toxic substance and promoting granulation, and can be used as substitute of squama Manis.
Chinese angelica: nature and taste: warm in nature, sweet and pungent in flavor; meridian tropism: it enters liver, heart and spleen meridians; the functional indications are as follows: enriching the blood; promoting blood circulation; carbuncle, cellulitis, sore and ulcer; injury from falling.
Ligusticum wallichii: meridian tropism: it enters liver and gallbladder meridians; the efficacy is as follows: has effects in promoting blood circulation and activating qi-flowing, and can be used for treating traumatic injury, blood stasis, swelling and pain.
Native copper: nature and taste: mild in nature and pungent in taste; the efficacy is as follows: disperse blood stasis, join bone and alleviate pain.
Rhizoma drynariae: the efficacy is as follows: has effects in dispelling blood stasis, relieving pain, promoting reunion of bone, and relieving lumbago.
Licorice root: nature and taste: mild in nature and sweet in taste; meridian tropism: entering heart, lung, spleen and stomach meridians; the efficacy is as follows: invigorating spleen and replenishing qi, clearing heat and detoxicating, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the intensity of some medicines.
Guangdan: nature and taste: slightly cold in nature, pungent, salty, and toxic in flavor; remove toxicity and promote granulation, heal wound. The external use can treat pyocutaneous disease, pyogenic infection, wound bleeding, burn and scald; can be used as basic agent for decocting plaster.
And (3) sesame oil: the efficacy is as follows: has effects of replenishing blood, moistening intestine, promoting fluid production, promoting lactation, and nourishing hair, and can be used as matrix of plaster.
The pharmacology of the formula of the invention is as follows:
(1) monarch drug: pyritum, rhizoma Drynariae, and Os Draconis.
(2) Ministerial drugs including Carthami flos, Notoginseng radix, radix Angelicae sinensis, sanguis Draxonis, Os Saigae Involucratae, semen Strychni, unguis Sus Domestica, sanguis Draxonis, Eupolyphaga Seu Steleophaga, Olibanum, herba Speranskiae Tuberculatae, cortex Cvettae, rhizoma Ligustici Chuanxiong, and buffalo hide.
(3) Adjuvant materials including artificial Moschus, Myrrha, Borneolum Syntheticum, Plumbum Preparatium, and oleum Sesami.
(4) A messenger drug: and (4) liquorice.
The frankincense, the eupolyphaga, the garden balsam stem, the buffalo hide, the keel, the root bark of chun and the ligusticum chuanxiong hort have the effects of activating blood and dissolving stasis, dredging channels and collaterals, diminishing inflammation and relieving pain and the like, and simultaneously promote the growth of callus and promote the healing of fracture. Safflower, notoginseng, Chinese angelica root, dragon's blood resin, mainly used for stopping bleeding, reducing swelling, alleviating pain, promoting blood circulation, removing blood stasis, relaxing muscles and tendons and dredging collaterals. The artificial musk has the effects of inducing resuscitation and refreshing mind, promoting blood circulation and dredging channels, relieving swelling and pain, and enhancing the effects of other medicines on promoting blood circulation and removing blood stasis. The bone of Sailong has the functions of dispelling wind, dredging collaterals, strengthening tendons and bones. Pyritum can be combined with Myrrha for promoting blood circulation and relieving pain, and can be used for reuniting bone and tendon; mo Yao can promote tissue regeneration and relieve swelling, and has the actions of activating blood and alleviating pain, reuniting bones and tendons, promoting tissue regeneration and relieving swelling. Dragon's blood is used for traumatic injury, pain due to blood stasis and unhealed abscess for a long time. The nux vomica and the ungula Sus domestica are used for relieving swelling, ulcerating carbuncle, dredging and activating collaterals, treating arthralgia due to wind-cold-dampness and stopping bleeding by external application, and the compatibility of the nux vomica and the ungula Sus domestica can improve the curative effect of removing blood stasis; the licorice has the function of harmonizing the toxicity of the nux vomica, can be used as a harmonizing agent of the formula and can enhance the effect of the medicines. Borneolum Syntheticum has analgesic effect. The sesame oil is also called sesame oil, has mild effect, can be used as a matrix of a plaster, has small irritation to skin, and is beneficial to long-time sticking. The Plumbum Preparatium has toxic substance removing effect, and can be used for fully bonding medicinal oil and making plaster.
Compared with the prior art, the invention has the following beneficial effects:
1. the plaster prepared by the invention is prepared by decocting different traditional Chinese medicines into paste by using a traditional method, is coated on cotton cloth and is pasted on a fracture part, the plaster can be permeated and absorbed by skin at the injury part and directly acts on the injury part, and swelling and pain of the fracture can be relieved by detumescence and blood circulation promotion in the early stage of the fracture; in the later period, the blood flow of the injured part is recovered by repairing tissues and accelerating the reconstruction of blood vessels, and the healing of the fracture is accelerated.
2. The invention has obvious effect on treating fracture, takes effect quickly, greatly shortens the healing time of fracture, has lower cost and no side effect, and has ideal effect through clinical verification.
3. The invention immerses the medicines in the sesame oil, fully fuses the medicines and the sesame oil, controls the dryness of the medicines, and sequentially puts the medicines into a container to be boiled according to the anti-boiling strength, so that the traditional Chinese medicines all exert the maximum efficacy.
Detailed Description
Reference will now be made in detail to various exemplary embodiments of the invention, the detailed description should not be construed as limiting the invention but as a more detailed description of certain aspects, features and embodiments of the invention.
It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. Further, for numerical ranges in this disclosure, it is understood that each intervening value, between the upper and lower limit of that range, is also specifically disclosed. Every smaller range between any stated value or intervening value in a stated range and any other stated or intervening value in a stated range is encompassed within the invention. The upper and lower limits of these smaller ranges may independently be included or excluded in the range.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Although only preferred methods and materials are described herein, any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention. All documents mentioned in this specification are incorporated by reference herein for the purpose of disclosing and describing the methods and/or materials associated with the documents. In case of conflict with any incorporated document, the present specification will control.
It will be apparent to those skilled in the art that various modifications and variations can be made in the specific embodiments of the present disclosure without departing from the scope or spirit of the disclosure. Other embodiments will be apparent to those skilled in the art from consideration of the specification. The specification and examples are exemplary only.
As used herein, the terms "comprising," "including," "having," "containing," and the like are open-ended terms that mean including, but not limited to.
EXAMPLE 1 preparation of a plaster for promoting blood circulation, relieving pain and setting fracture
(1) Weighing the following raw materials in parts by mass: 30 parts of frankincense, 30 parts of eupolyphaga, 25 parts of myrrh, 40 parts of keel, 25 parts of borneol, 25 parts of sialon bone, 25 parts of dragon's blood flower, 25 parts of garden balsam stem, 30 parts of root bark of chun rhizomes, 25 parts of artificial musk, 25 parts of saffron crocus, 25 parts of pseudo-ginseng, 25 parts of dragon's blood, 0.5 part of nux vomica, 25 parts of pig nail, 25 parts of angelica, 40 parts of ligusticum chuanxiong hort, 40 parts of native copper, 40 parts of rhizoma drynariae, 40 parts of liquorice, 25 parts of minium and 1200 parts of sesame oil;
(2) cutting the frankincense, the dried body of ground beetle, the myrrh, the buffalo hide, the keel, the borneol, the sialon bone, the dragon's blood flower, the garden balsam stem, the root bark of chun white, the artificial musk, the saffron, the pseudo-ginseng, the dragon's blood, the nux vomica, the pig nail, the Chinese angelica, the ligusticum chuanxiong hort, the native copper, the rhizoma drynariae and the liquorice which are weighed in the step (1) into small pieces respectively;
(3) soaking the cut traditional Chinese medicines in the step (2) in sesame oil for 24 hours;
(4) fishing out the traditional Chinese medicine soaked in the sesame oil in the step (3) and draining the oil;
(5) the sesame oil soaked with the traditional Chinese medicines is poured into a container for preheating at 80 ℃, then the traditional Chinese medicines with the dry oil content controlled are added into the container in batches for heating and decocting the traditional Chinese medicines, the heating temperature is controlled to be 200-300 ℃, a poplar stick is used for stirring continuously in the decocting process, the fire is not too large, the decoction is carried out for 5-6 hours, and the medicine residues are fished out and are continuously decocted;
(6) taking out a drop of medicinal oil, and dripping into water of 8-10 deg.C, wherein if the medicinal oil is aggregated in water to form a group, it indicates that the medicinal oil has been decocted;
(7) after the medicinal oil is decocted, the medicinal oil is adjusted to be small fire, the Guangdong lead is added, the stirring is carried out continuously while the Guangdong lead is added, a large amount of smoke is formed at the moment, and when the smoke is changed from green smoke to white smoke, the plaster is decocted;
(8) pouring the decocted plaster into a basin with a temperature of 8-10 ℃, stirring along one direction while inverting to make the plaster gather into a block, soaking for 3-7 days to remove fire toxin, and replacing clear water once every 24h to obtain the plaster for promoting blood circulation, relieving pain and setting fracture.
The beneficial effects of the plaster prepared according to example 1 of the present invention are further illustrated by the clinical treatment profile below:
case selection criteria: all patients were selected as closed fracture patients and patients without fracture but with severe soft tissue damage, with the skin visually observed to be intact and unbroken.
Patient diagnostic criteria: all patients who see a doctor all observe whether the external appearance of the affected part is swollen and malformed by physical examination, whether the local part has pain or not, whether the bone is rubbed with sound and is rubbed with the bone, and then all carry out X-ray examination: the continuity of the bone is interrupted, and the broken ends are aligned well.
The evaluation standard of curative effect is as follows: standard of fracture healing: all closed fracture patients are subjected to X-ray examination after being treated for 4-6 weeks, the X-ray indicates that the fracture line is fuzzy, callus formation can be seen around the fracture line, swelling of affected parts disappears, no pressure pain exists, and the patient can walk freely. Healing criteria for ligament and soft tissue injuries: after 3-4 weeks of treatment, the swelling of the affected part disappears, no tenderness exists and the walking is free.
The method is effective: the local swelling and pain of the patient disappeared, and the fracture line was blurred and callus was formed on the X-ray examination.
Secondly, invalidation: local swelling is not improved and tends to be aggravated, and fracture lines are clear and callus formation is not seen by X-ray examination.
The treatment scheme comprises the following steps: uniformly spreading the decocted plaster on cotton cloth with a size of 2-3 times of the wound area, sticking the plaster on the affected part, fixing the fracture part with splint or Gypsum Fibrosum, and standing for 4-6 weeks. A single plaster is pasted for 7-10 days as a treatment course, and the curative effect is counted after 4-5 treatment courses. The plaster is applied to the affected part in the same way for patients with ligament injury and soft tissue injury, and is rested in bed for 3 weeks, and is fixed with plaster for 3 weeks for serious ligament injury. A single plaster is applied for 7-10 days as a treatment course, and the curative effect is counted after 3-4 treatment courses.
Contraindications for the present invention: it is not suitable for patients with open fracture, fracture and skin injury, and pregnant women.
100 patients with bone fracture treated by the plaster are selected and counted, wherein 64 cases are male and 36 cases are female. 1-20 years old: 30 cases; 21-45 years old: 40 cases; 46-65 years old: 18 cases; age 66 or older: and (12) cases. No adverse reaction occurs in the treatment process. The treatment effect is shown in the following table 1:
TABLE 1
Figure BDA0002612117060000071
As can be seen from the table 1, the plaster prepared by the invention can treat not only fracture but also ligament and soft tissue injury, has prominent clinical significance and obvious curative effect, wherein the cure rate of the fracture patients can reach 91.7%; the effective rate of the patients with ligament and soft tissue injuries is 100 percent, and the cure rate can reach 92.9 percent.
At present, the healing time of the clinical adolescent closed fracture is 6-8 weeks, more serious people are generally more than 12 weeks, and the results of clinical statistical data show that: in the process of treating the fracture, the healing time of 30 juvenile patients treated by the plaster is strictly regulated to be 4-6 weeks; the fracture of middle-aged and old people over 45 years old generally has clinical healing time of about 8-12 weeks, and 30 cases of middle-aged and old fracture patients have healing time of 6-8 weeks, so that the fracture healing time of the patients treated by the plaster is shortened by 2-4 weeks compared with the normal clinical healing time. The healing time of patients with ligament and soft tissue injuries is 6 weeks, and the healing time of 28 patients treated by the plaster is 3-4 weeks, which shows that the healing time of ligament and soft tissue injuries can be shortened by using the plaster. Therefore, the plaster can greatly shorten the healing time of patients and reduce the economic burden of the patients.
Typical cases are:
the patient is 46 years old, falls down carelessly when walking, touches the palm of the left hand, and has outer tube malformation, pain and limited activity, the far-end continuity of the left radius is interrupted as seen in the X-ray examination in emergency treatment, the alignment of the broken end is not good enough, no obvious abnormality is seen, the patient is subjected to fracture manual reduction with the consent of the patient, then the alignment of the fracture end which is seen in the X-ray is well restored, the plaster is externally applied to the patient, the splint is externally fixed, the medicine is changed once in 7 days, the blurring of the fracture line which is seen in the X-ray is rechecked after 6 weeks of treatment, and poroma growth is seen at the fracture part. After the external fixation is removed, the patient does not complain of discomfort, the fingers move freely, the wrist joint movement needs to be exercised step by step and is basically recovered to be normal, and the patient is prompted to be cured.
② patients, male, 24 years old, will sprain carelessly when playing basketball, then the right ankle joint will swell, pain, activity will be limited, the X-ray examination will show good continuity of cortex lycii, no fracture sign, the change of joint structure, the widening of ankle point and swelling of surrounding soft tissue. Diagnosis according to signs and related examinations: treating right side tibiofibular ligament injury, externally applying plaster, externally fixing plaster, advising the patient to brake for rest, raising the affected limb, removing plaster after 3-4 weeks of treatment, and externally fixing, wherein the affected part of the patient has no pressure pain, and can walk freely to prompt the patient to heal.
The patient, the woman, 30 years old, sprain carelessly when going down stairs, the left foot gall appears in the way, the activity is restricted, left foot fifth metatarsal basilar part fracture is seen in the X line inspection, broken end counterpoint is to the line good, diagnose according to patient's symptom and relevant supplementary inspection for left foot fifth metatarsal basilar part fracture, agree to the back through the patient and go on the plaster external application, the gypsum external fixation, order the patient to rest in bed, raise the affected limb, it is fuzzy to recheck the visible broken bone line of X line after 6 weeks of treatment, visible callus parcel around, the affected part swelling disappears, no tenderness, the patient can independently walk, suggestion this patient has healed.
Example 2
The same as example 1 except that 30 parts of buffalo hide were added to the raw material.
100 patients with bone fracture treated by the plaster are selected and counted, and no adverse reaction occurs in the treatment process. The treatment effect is shown in the following table 2:
TABLE 2
Figure BDA0002612117060000081
Figure BDA0002612117060000091
As can be seen from Table 2, the bone-knitting plaster prepared by adding buffalo hide has improved cure rate and effective rate, which shows that the addition of buffalo hide can effectively treat fracture diseases.
Example 3
The difference from example 1 is that the keels are replaced with magnets.
100 patients with bone fracture treated by the plaster are selected and counted, and no adverse reaction occurs in the treatment process. The treatment effect is shown in the following table 3:
TABLE 3
Figure BDA0002612117060000092
As can be seen from Table 3, although the effect of the keel and the magnet is similar, the effect of the bone-knitting plaster prepared by the keel is obviously reduced, which shows that the raw materials in the bone-knitting plaster prepared by the invention are cooperated with each other, and each raw material is compatible with other raw materials while playing the effect of the raw material, thereby playing a greater effect. The dragon bone, the frankincense, the eupolyphaga, the garden balsam stem, the root bark of chun and the ligusticum chuanxiong hort play roles of activating blood and dissolving stasis, dredging channels and collaterals, diminishing inflammation and relieving pain together, and simultaneously have the effects of promoting callus growth and promoting fracture healing.
Example 4
The difference is that the nux vomica is replaced by the scorpion in the same embodiment 1.
100 patients with bone fracture treated by the plaster are selected and counted, and no adverse reaction occurs in the treatment process. The therapeutic effect is shown in the following table 4:
TABLE 4
Figure BDA0002612117060000093
It can be seen from table 4 that, although the efficacy of nux vomica is similar to that of scorpion, the cure rate and the effective rate of patients are reduced after the nux vomica is replaced by the scorpion, because the compatibility of the nux vomica and the unguis Sus domestica can increase the efficacy of removing blood stasis, and the addition of the liquorice can adjust the toxicity of the nux vomica so as to enhance the efficacy.
Example 5
The difference is that the eupolyphaga is replaced by spatholobus suberectus.
100 patients with bone fracture treated by the plaster are selected and counted, and no adverse reaction occurs in the treatment process. The therapeutic effect is shown in the following table 5:
TABLE 5
Figure BDA0002612117060000101
From table 5, it can be seen that the cure rate and the effective rate of the bone fracture patients are reduced after the eupolyphaga is replaced by the eupolyphaga sinensis, which indicates that the eupolyphaga, the dragon bone, the frankincense, the garden balsam stem, the root bark of chun rhizomes and the ligusticum chuanxiong hort play roles of activating blood and dissolving stasis, dredging channels and collaterals, diminishing inflammation and relieving pain together, and simultaneously have the effects of promoting the growth of callus and promoting the healing of fracture.
Example 6
The difference from example 1 is that Pyritum is replaced by eucommia ulmoides.
100 patients with bone fracture treated by the plaster are selected and counted, and no adverse reaction occurs in the treatment process. The therapeutic effect is as follows in table 6:
TABLE 6
Figure BDA0002612117060000102
It can be seen from table 6 that the cure rate and the effective rate of the patients with bone fracture are both reduced obviously after the pyrite is replaced by the eucommia ulmoides, because the pyrite and the myrrh have the efficacy of promoting blood circulation and relieving pain, the pyrite can reunite the tendons of bones, and the myrrh can promote granulation and reduce swelling, and the effects of promoting blood circulation and relieving pain, reuniting the tendons of bones and promoting granulation and reducing swelling are achieved when the pyrite and the myrrh are combined.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included therein.

Claims (9)

1. The plaster for promoting blood circulation, relieving pain and setting fracture is characterized by comprising the following raw materials in parts by mass:
25-35 parts of frankincense, 25-35 parts of eupolyphaga, 20-30 parts of myrrh, 35-45 parts of keel, 20-30 parts of borneol, 20-30 parts of sialon bone, 20-30 parts of dragon's blood flower, 20-30 parts of garden balsam stem, 25-35 parts of chunshige root bark, 20-30 parts of artificial musk, 20-30 parts of saffron, 20-30 parts of pseudo-ginseng, 20-30 parts of dragon's blood, 0.2-0.5 part of nux vomica, 20-30 parts of pig nail, 20-30 parts of angelica, 35-45 parts of ligusticum chuanxiong hort, 35-45 parts of native copper, 35-45 parts of rhizoma drynariae, 35-45 parts of liquorice, 20-30 parts of Guangdan and 1300 parts of sesame oil 1100.
2. The plaster for promoting blood circulation, stopping pain and setting bone according to claim 1, wherein the raw materials of the plaster further comprise 25-35 parts of buffalo hide.
3. The plaster for promoting blood circulation, relieving pain and setting bone according to claim 1, wherein the plaster raw materials comprise the following raw materials in parts by mass:
30 parts of frankincense, 30 parts of eupolyphaga, 25 parts of myrrh, 40 parts of keel, 25 parts of borneol, 25 parts of sialon bone, 25 parts of dragon's blood flower, 25 parts of garden balsam stem, 30 parts of root bark of chun rhizomes, 25 parts of artificial musk, 25 parts of saffron crocus, 25 parts of pseudo-ginseng, 25 parts of dragon's blood, 0.5 part of nux vomica, 25 parts of pig nail, 25 parts of angelica, 40 parts of ligusticum chuanxiong hort, 40 parts of native copper, 40 parts of rhizoma drynariae, 40 parts of liquorice, 25 parts of minium and 1200 parts of sesame oil.
4. The process for preparing a plaster for promoting blood circulation, stopping pain and setting bone according to any one of claims 1 to 3, which comprises the following steps:
(1) weighing the required raw materials;
(2) cutting the frankincense, the dried body of ground beetle, the myrrh, the buffalo hide, the keel, the borneol, the sialon bone, the dragon's blood flower, the garden balsam stem, the root bark of chun white, the artificial musk, the saffron, the pseudo-ginseng, the dragon's blood, the nux vomica, the pig nail, the Chinese angelica, the ligusticum chuanxiong hort, the native copper, the rhizoma drynariae and the liquorice which are weighed in the step (1) into small pieces respectively;
(3) soaking the cut traditional Chinese medicines in the step (2) in sesame oil;
(4) fishing out the traditional Chinese medicine soaked in the sesame oil in the step (3) and draining the oil;
(5) pouring sesame oil soaked with the traditional Chinese medicines into a container for preheating, adding the traditional Chinese medicines with the dry oil content controlled into the container in batches, heating and decocting the traditional Chinese medicines, stirring continuously in the decocting process, fishing out dregs after decocting for a period of time, and continuing to decoct;
(6) after the medicinal oil is decocted in the step (5), adding minium with small fire, and continuing decocting until the plaster is decocted;
(7) and (3) after the plaster is decocted, annealing treatment is carried out to obtain the plaster for promoting blood circulation, relieving pain and setting bone.
5. The preparation method of the plaster for promoting blood circulation, stopping pain and setting bone according to claim 4, wherein the soaking time in step (3) is 24 h.
6. The method for preparing a plaster for promoting blood circulation, relieving pain and setting bone according to claim 4, wherein the preheating temperature in the step (5) is 80 ℃; the heating temperature is 200-300 ℃; and after the decoction time is 5-6 hours, fishing out the decoction dregs, and continuing to decoct.
7. The preparation method of the plaster for promoting blood circulation, stopping pain and setting bone according to claim 4, wherein the method for judging the decoction of the medicinal oil in the step (6) comprises the following steps: taking out a drop of medicinal oil, and dripping into water of 8-10 deg.C, wherein if the medicinal oil is aggregated in water to form a group, it indicates that the medicinal oil has been decocted;
the method for judging whether the plaster is decocted in the step (6) comprises the following steps: stirring while adding Plumbum Preparatium, and when the smoke changes from green smoke to white smoke, it indicates that the plaster is decocted.
8. The preparation method of the plaster for promoting blood circulation, stopping pain and setting bone according to claim 4, wherein the annealing treatment method in the step (7) comprises the following steps: pouring the decocted plaster into 8-10 deg.C water, stirring to make the plaster agglomerate, soaking for 3-7 days to remove fire toxin, and replacing clear water once every 24 hr.
9. The bone-setting plaster of claim 1, wherein the method of use of the bone-setting plaster is: softening the plaster, then uniformly applying on cotton cloth, and applying on affected part.
CN202010757646.XA 2020-07-31 2020-07-31 Plaster for promoting blood circulation, relieving pain and setting fracture and preparation method thereof Pending CN111773300A (en)

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