CN113796949A - Pulsed electric field ablation system and control method thereof - Google Patents

Pulsed electric field ablation system and control method thereof Download PDF

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Publication number
CN113796949A
CN113796949A CN202111129789.7A CN202111129789A CN113796949A CN 113796949 A CN113796949 A CN 113796949A CN 202111129789 A CN202111129789 A CN 202111129789A CN 113796949 A CN113796949 A CN 113796949A
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China
Prior art keywords
electrodes
electric field
electrode
power supply
pulsed electric
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CN202111129789.7A
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Chinese (zh)
Inventor
周拓
方正
吴越鹏
鄢盛杰
司鹏
张勇
戴振华
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Shanghai Hongtong Industrial Co ltd
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Shanghai Hongtong Industrial Co ltd
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Priority to CN202111129789.7A priority Critical patent/CN113796949A/en
Publication of CN113796949A publication Critical patent/CN113796949A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206—Generators therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00732—Frequency

Abstract

The application discloses a pulsed electric field ablation system and a control method thereof, wherein the ablation system comprises: the power supply module comprises two output ends with opposite polarities; an ablation catheter comprising a plurality of electrode pairs; each electrode pair comprises a pair of electrodes which are adjacent in position and respectively connected with the two output ends of the power supply module; two electrodes which are adjacent and belong to different electrode pairs are connected with the same output end of the power supply module. In the application, the adjacent electrodes are opposite in polarity only when the same electrode pair is conducted, and the situation that the polarity of one electrode is opposite to that of two adjacent electrodes does not exist, so that the contact resistance of the adjacent electrodes cannot multiplex and divide voltage, the voltage of the target resistance on the circuit of the electrode pair is higher, and the electric field intensity is more ideal.

Description

Pulsed electric field ablation system and control method thereof
Technical Field
The invention relates to the field of electronic instruments, in particular to a pulsed electric field ablation system and a control method thereof.
Background
Currently, for arrhythmia patients who cannot be controlled by drugs, non-drug treatment means such as catheter ablation and pacemaker implantation are usually selected for heart rate control to improve symptoms. The ablation catheters adopted by catheter ablation are classified according to the number of electrodes and are divided into a single-electrode catheter and a multi-electrode catheter, wherein the single-electrode catheter has low unit efficiency and takes long time; the multi-electrode conduit has more contact points of the electrodes, and the contact resistance of the contact points of the adjacent electrodes generates a voltage division effect due to multiplexing, so that the voltage of the target resistance on an electric path of the conduit is reduced, the action effect of an electric field is weakened, the ideal electric field intensity cannot be achieved, and the effect of the whole multi-electrode conduit is poor.
Therefore, how to provide a solution to the above technical problems is a problem to be solved by those skilled in the art.
Disclosure of Invention
In view of the above, the present invention is directed to a pulsed electric field ablation system with a more desirable electric field distribution. The specific scheme is as follows:
a pulsed electric field ablation system comprising:
the power supply module comprises two output ends with opposite polarities;
an ablation catheter comprising a plurality of electrode pairs;
each electrode pair comprises a pair of electrodes which are adjacent in position and respectively connected with the two output ends of the power supply module; two electrodes which are adjacent and belong to different electrode pairs are connected with the same output end of the power supply module.
Preferably, the ablation catheter further comprises one or more suspended electrodes, and the suspended electrodes are not connected with the two output ends of the power supply module.
Preferably, only two electrodes spaced apart from the suspended electrode are connected to the same output terminal of the power module.
Preferably, the power supply module includes:
a power supply circuit including a plurality of switching tubes;
and the switching tube is controlled to be switched on and off according to a first preset frequency, so that the power supply circuit outputs positive pulses and negative pulses through the two output ends respectively.
Preferably, the pulsed electric field ablation system further comprises a switching array, and a plurality of the electrodes are connected with the output end of the power supply module through switches of the switching array.
Preferably, the switch array controls the on/off of the switch according to a second preset frequency so as to move the position of at least one electrode pair.
Preferably, the ablation catheter specifically comprises:
the electrode signal receiving device comprises a handle, a conduit, a plurality of electrodes positioned at the head end of the conduit, and a plurality of leads positioned in the handle and the conduit, connected with the plurality of electrodes one by one and used for receiving the pulse signals.
Preferably, a plurality of said electrodes are distributed along the long axis of said catheter.
Preferably, the spatial structure of the head end of the conduit in the operating state is changed into a ring shape, a spiral shape or a basket shape.
Correspondingly, the application also discloses a control method of the pulsed electric field ablation system, which is applied to the pulsed electric field ablation system of any one of the above systems, and the control method comprises the following steps:
determining a plurality of electrode pairs of an ablation catheter, the electrode pairs including a pair of electrodes positioned adjacently;
according to an electrode connection rule, connecting the electrode pairs with two output ends of the power supply module, wherein the two output ends have opposite polarities, and the electrode connection rule specifically comprises the following steps:
one pair of electrodes in each electrode pair is respectively connected with two output ends of the power supply module;
two electrodes which are adjacent and belong to different electrode pairs are connected with the same output end of the power supply module.
The application discloses pulsed electric field ablation system includes: the power supply module comprises two output ends with opposite polarities; an ablation catheter comprising a plurality of electrode pairs; each electrode pair comprises a pair of electrodes which are adjacent in position and respectively connected with the two output ends of the power supply module; two electrodes which are adjacent and belong to different electrode pairs are connected with the same output end of the power supply module. In the application, the adjacent electrodes are opposite in polarity only when the same electrode pair is conducted, and the situation that the polarity of one electrode is opposite to that of two adjacent electrodes does not exist, so that the contact resistance of the adjacent electrodes cannot multiplex and divide voltage, the voltage of the target resistance on the circuit of the electrode pair is higher, and the electric field intensity is more ideal.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a schematic diagram of a pulsed electric field ablation system in accordance with an embodiment of the present invention;
FIG. 2 is an equivalent circuit diagram of the electrical path of a plurality of electrodes in the prior art;
FIG. 3 is an equivalent circuit diagram of the electrical path of a plurality of electrodes in an embodiment of the present invention;
FIG. 4 is a schematic diagram of a particular pulsed electric field ablation system in accordance with an embodiment of the present invention;
FIG. 5 is a schematic view of an ablation catheter in accordance with an embodiment of the invention;
FIGS. 6a and 6b are schematic views of the effective range of the pulsed electric field ablation system with annularly distributed electrodes in the present embodiment and in the prior art, respectively;
fig. 7a and 7b are schematic views of the effective range of the pulsed electric field ablation system with long-axis distribution of electrodes in the present embodiment and the prior art, respectively.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the multi-electrode catheter in the prior art, because the contact points of the electrodes are more, the contact resistance of the contact points of the adjacent electrodes generates a voltage division effect due to multiplexing, the voltage of a target resistor on an electric path of the catheter is reduced, the action effect of an electric field is weakened, the ideal electric field intensity cannot be achieved, and the effect of the whole multi-electrode catheter is poor. In the application, the adjacent electrodes are opposite in polarity only when the same electrode pair is conducted, and the situation that the polarity of one electrode is opposite to that of two adjacent electrodes does not exist, so that the contact resistance of the adjacent electrodes cannot multiplex and divide voltage, the voltage of the target resistance on the circuit of the electrode pair is higher, and the electric field intensity is more ideal.
An embodiment of the present invention discloses a pulsed electric field ablation system, as shown in fig. 1, including:
the power supply module 1 comprises two output ends with opposite polarities;
an ablation catheter 2 comprising a plurality of electrode pairs;
each electrode pair comprises a pair of electrodes which are adjacent in position and respectively connected with two output ends of the power module 1; two electrodes which are adjacent in position and belong to different electrode pairs are connected with the same output end of the power module 1.
It is understood that all electrode pairs and the number of electrodes in the plurality of electrode pairs in the present embodiment may be configured according to requirements, and may be generally set to 30 electrodes. In this embodiment, the two output ends of the power module 1 with opposite polarities are respectively the positive output end and the negative output end, and the polarity corresponding to any one electrode after the two output ends are connected with the electrode is determined. According to the connection relationship between the electrodes and the output end in the electrode pair in the embodiment: two electrodes adjacent to each other in the electrode pair are respectively connected to two output ends of the power module 1, two electrodes adjacent to each other in the positions belonging to different electrode pairs are respectively connected to the same output end of the power module 1, for example, ten electrodes are taken as an example, one electrode pair is arranged in a round bracket, and a plurality of electrode pairs are arranged in a position sequence in a square bracket, and the polarity setting of the electrodes can be as follows:
a.[(+，-)，(-，+)，(+，-)，(-，+)，(+，-)]；
b.[(-，+)，(+，-)，(-，+)，(+，-)，(-，+)]；
in general, at least one electrode pair should be included in the ablation catheter 2; it is also possible to alternate between different protocols to adjust the position of the working electrode pair, such as between protocols a and b, so that the region of action of the electrical path is changed by moving the position of the working electrode pair when the ablation catheter 2 is not physically moved. For the same ten electrodes, the polarity arrangement in the prior art is based on the idea that the polarities of the adjacent electrodes are opposite, that is:
[+，-，+，-，+，-，+，-，+，-]；
there is no isolated electrode pair at this time, and any electrode and its neighboring electrode become one working electrode pair.
It can be understood that two electrodes with the same polarity cannot be conducted, and at this time, the contact resistance between the two electrodes and the contact points thereof and the equivalent resistance between the two contact resistances and the target resistance are extremely large, and generally considered to be difficult to conduct; two electrodes with opposite polarities are easier to conduct, and two adjacent electrodes with opposite polarities are easier to establish an electric path between the contact resistance of the two electrodes and the contact point of the two electrodes and the target resistance between the two contact resistances.
From the above description, it can be seen that the equivalent circuit diagram of the prior art is obtained, as shown in fig. 2, the electrode pair of fig. 2 is not isolated, each electrode has opposite polarity to the adjacent electrodes on the left and right sides and establishes an electrical path, and the contact resistance R of the adjacent electrodesContact withThe multiplexing produces a voltage division effect resulting in a target resistance R being applied to the electrical pathViasI.e. a lower voltage is applied to the patient impedance;in the connection structure of the power module 1 and the ablation catheter 2 in this embodiment, only two electrodes in the electrode pair can establish an electrical path, even if adjacent electrodes exist outside the electrodes, the electrodes do not establish an electrical path with the electrodes in the electrode pair due to the same polarity, and an equivalent circuit of the electrodes is shown in fig. 3, each electrode pair exists in an isolated manner, and there is no multiplexing contact resistance R of the two electrical pathsContact withThe equivalent contact resistance is lower, so that the target resistance R is on the electric path of the electrode pairViasThe voltage of (2) is higher, and the equivalent electric field strength is more ideal.
Further, referring to fig. 1 and 4, in a specific structure, the power module 1 includes:
a power supply circuit 11 including a plurality of switching tubes;
and the pulse controller 12 is used for controlling the on-off of the switching tube according to a first preset frequency so that the power supply circuit 11 outputs positive pulses and negative pulses through two output ends respectively.
It can be understood that the power supply circuit 11 mainly includes a power supply and a switching tube, and when the switching tube is turned on, the power supply outputs voltage to the output end, so that the electrode is connected to the power supply.
Further, from the viewpoint of safety and operational effect, the output of the power supply is usually direct current, so the power supply may include AC220V commercial power, an AC/DC conversion unit for converting AC220V into DC23V, a DC/DC conversion unit, and a voltage stabilizing capacitor, and further, considering the voltage output of different gears, two DC/DC conversion units may be provided, which respectively use two voltage regulating control logics to respectively output two voltages HV1+ and HV2+, and correspond to two voltage stabilizing capacitors C1 and C2, and a single-pole double-throw voltage selection switch SPDT1 is added for selecting a voltage gear.
It can be understood that the power module 1 outputs the positive voltage and the negative voltage at two output terminals simultaneously, and the connection between the power supply and the electrode pair is controlled by the on/off of the switch tube on the power supply circuit 11. Furthermore, considering the flexible selection of the polarities of the two output ends, the switching tubes Q1-Q4 are arranged in a full-control inversion structure, and the polarities of the two output ends are opposite to each other in that the switching tubes Q1 and Q4 are conducted and the switching tubes Q2 and Q3 are conducted. Further, the voltage output of the output end is represented in a pulse form in a time domain, and is realized by sending a pulse signal to the driving ends of the switching tubes Q1-Q4 through the pulse controller 12, for example, in fig. 4, when Q1 and Q4 are turned on, a positive pulse + and a negative pulse are respectively output, the frequency corresponding to the pulse signal and the pulse voltage is a first preset frequency, the setting is performed according to the working requirement, and a voltage measuring unit and a current measuring unit can be further arranged to perform current and voltage monitoring and protection on the pulse voltage.
Further, the pulsed electric field ablation system in this embodiment further includes a switching array 3, and the plurality of electrodes, i.e., the electrodes 1 to n, and the back plate of the ablation catheter 2 are connected to the output end of the power module 1 through the switch of the switching array 3.
It can be understood that a plurality of switches are disposed in the switching array 3, each electrode can be connected to two output terminals of the power module 1 through one switch, specifically, the switches here can be a single-pole double-throw switch in which a movable terminal is connected to an electrode, and two stationary terminals are respectively connected to two output terminals, or can be a switch pair, the switch pair includes two switches in which a first terminal is connected to a switch, a second terminal is connected to two output terminals, and the two switches cannot be closed at the same time, as shown in fig. 4.
It will be appreciated that the presence of these switches provides the condition that each electrode can be connected to any output of the power module 1, and that an array controller may be added to set the second predetermined frequency to control the on/off of the switches, according to the operational requirements, so as to move the position of at least one electrode pair to adjust the range of action of the ablation catheter 2.
Further, the ablation catheter 2 may further include one or more suspended electrodes, which are not connected to the two output ends of the power module 1, except for the plurality of electrodes. The suspended electrodes and the electrodes in the electrode pairs are arranged on the ablation catheter 2 according to a certain rule, and besides the requirement that the positions of the two electrodes in the electrode pair are adjacent, the positions between the electrode pair, between the suspended electrode and between the electrode pair and the suspended electrode can be adjusted according to requirements.
In order to further avoid multiplexing voltage division influence of contact resistance between adjacent electrodes, only two electrodes of the spaced suspended electrodes are connected with the same output end of the power module 1.
Taking ten electrodes as an example, 0 represents a floating electrode, and the position of the floating electrode can be set between the electrode pair, such as:
[(+，-)，(0)，(0)，(-，+)，(0)，(+，-)，(0)]；
it can be understood that determining one electrode as a floating electrode and the other positive or negative electrode can be determined according to the state of the switch corresponding to the electrode in the switching array 3, and when the switch is not connected to both output terminals of the power module 1, the electrode serves as the floating electrode.
Further, referring to fig. 5, the ablation catheter 2 specifically includes:
the pulse signal generator comprises a handle 21, a guide pipe 22, a plurality of electrodes 23 positioned at the head end of the guide pipe 22, and a plurality of leads which are positioned inside the handle 21 and the guide pipe 22, are connected with the plurality of electrodes 23 one by one and receive pulse signals.
Among them, a plurality of electrodes 23 located at the head end of the conduit 22, specifically, one electrode or suspended electrode in the electrode pair.
Further, a plurality of electrodes 23 are distributed along the long axis of the catheter 22, and typically, an ablation catheter 2 may include up to 30 electrodes. It will be understood that the head end of the conduit 22 is a flexible pipe with a variable shape, so that the spatial structure of the head end of the conduit 22 in the working state can be changed into a ring shape, a spiral shape or a basket shape in addition to the straight-axis state, and the specific shape can be designed according to actual requirements.
Further, finite element simulation calculation is performed on the pulsed electric field ablation systems in the present embodiment and the prior art, respectively, wherein fig. 6a and fig. 6b are effective ranges of the pulsed electric field ablation systems in the present embodiment and the prior art, respectively, the maximum effective depth of the present embodiment is increased by about 20%, fig. 7a and fig. 7b are effective ranges of the pulsed electric field ablation systems in the present embodiment and the prior art, respectively, which are distributed along the long axis of the electrode, and the maximum effective depth of the present embodiment is increased by about 30%, which shows that the present embodiment can generate an electric field strength with an ideal significant intensity.
The application discloses pulsed electric field ablation system includes: the power supply module comprises two output ends with opposite polarities; an ablation catheter comprising a plurality of electrode pairs; each electrode pair comprises a pair of electrodes which are adjacent in position and respectively connected with the two output ends of the power supply module; two electrodes which are adjacent and belong to different electrode pairs are connected with the same output end of the power supply module. In the application, the adjacent electrodes are opposite in polarity only when the same electrode pair is conducted, and the situation that the polarity of one electrode is opposite to that of two adjacent electrodes does not exist, so that the contact resistance of the adjacent electrodes cannot multiplex and divide voltage, the voltage of the target resistance on the circuit of the electrode pair is higher, and the electric field intensity is more ideal.
Correspondingly, the embodiment of the application also discloses a control method of the pulsed electric field ablation system, which is applied to the pulsed electric field ablation system of any one of the above embodiments, and the control method comprises the following steps:
determining a plurality of electrode pairs of an ablation catheter, the electrode pairs including a pair of electrodes positioned adjacently;
according to an electrode connection rule, connecting the electrode pairs with two output ends of the power supply module, wherein the two output ends have opposite polarities, and the electrode connection rule specifically comprises the following steps:
one pair of electrodes in each electrode pair is respectively connected with two output ends of the power supply module;
two electrodes which are adjacent and belong to different electrode pairs are connected with the same output end of the power supply module.
In the application, the adjacent electrodes are opposite in polarity only when the same electrode pair is conducted, and the situation that the polarity of one electrode is opposite to that of two adjacent electrodes does not exist, so that the contact resistance of the adjacent electrodes cannot multiplex and divide voltage, the voltage of the target resistance on the circuit of the electrode pair is higher, and the electric field intensity is more ideal.
Finally, it should also be noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The pulsed electric field ablation system and the control method thereof provided by the present invention are described in detail above, and the principle and the implementation of the present invention are explained in the present document by applying specific examples, and the above description of the embodiments is only used to help understanding the method of the present invention and the core idea thereof; meanwhile, for a person skilled in the art, according to the idea of the present invention, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present invention.

Claims (10)

1. A pulsed electric field ablation system, comprising:
the power supply module comprises two output ends with opposite polarities;
an ablation catheter comprising a plurality of electrode pairs;
each electrode pair comprises a pair of electrodes which are adjacent in position and respectively connected with the two output ends of the power supply module; two electrodes which are adjacent and belong to different electrode pairs are connected with the same output end of the power supply module.
2. The pulsed electric field ablation system of claim 1, wherein the ablation catheter further comprises one or more suspended electrodes that are not connected to both of the output terminals of the power module.
3. The pulsed electric field ablation system of claim 2,
only two electrodes which are separated from the suspended electrode are connected with the same output end of the power supply module.
4. The pulsed electric field ablation system of claim 1, wherein the power module comprises:
a power supply circuit including a plurality of switching tubes;
and the switching tube is controlled to be switched on and off according to a first preset frequency, so that the power supply circuit outputs positive pulses and negative pulses through the two output ends respectively.
5. The pulsed electric field ablation system of claim 4, further comprising a switching array, a plurality of said electrodes being connected to said output of said power module through switches of said switching array.
6. The pulsed electric field ablation system of claim 5, wherein the switching array switches the switch on and off according to a second predetermined frequency to shift the position of at least one of the electrode pairs.
7. The pulsed electric field ablation system of any one of claims 1 to 6, wherein the ablation catheter specifically comprises:
the electrode signal receiving device comprises a handle, a conduit, a plurality of electrodes positioned at the head end of the conduit, and a plurality of leads positioned in the handle and the conduit, connected with the plurality of electrodes one by one and used for receiving the pulse signals.
8. The pulsed electric field ablation system of claim 7, wherein a plurality of said electrodes are distributed along the long axis of said catheter.
9. The pulsed electric field ablation system of claim 8,
the space structure of the head end of the conduit is changed into a ring shape, a spiral shape or a basket shape under the working state.
10. A control method of a pulsed electric field ablation system, which is applied to the pulsed electric field ablation system according to any one of claims 1 to 9, the control method comprising:
determining a plurality of electrode pairs of an ablation catheter, the electrode pairs including a pair of electrodes positioned adjacently;
according to an electrode connection rule, connecting the electrode pairs with two output ends of the power supply module, wherein the two output ends have opposite polarities, and the electrode connection rule specifically comprises the following steps:
one pair of electrodes in each electrode pair is respectively connected with two output ends of the power supply module;
two electrodes which are adjacent and belong to different electrode pairs are connected with the same output end of the power supply module.
CN202111129789.7A 2021-09-26 2021-09-26 Pulsed electric field ablation system and control method thereof Pending CN113796949A (en)

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CN202111129789.7A CN113796949A (en) 2021-09-26 2021-09-26 Pulsed electric field ablation system and control method thereof

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Application Number Priority Date Filing Date Title
CN202111129789.7A CN113796949A (en) 2021-09-26 2021-09-26 Pulsed electric field ablation system and control method thereof

Publications (1)

Publication Number Publication Date
CN113796949A true CN113796949A (en) 2021-12-17

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