CN113759139A - Sample analyzer and liquid supply method thereof - Google Patents
Sample analyzer and liquid supply method thereof Download PDFInfo
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- CN113759139A CN113759139A CN202010485856.8A CN202010485856A CN113759139A CN 113759139 A CN113759139 A CN 113759139A CN 202010485856 A CN202010485856 A CN 202010485856A CN 113759139 A CN113759139 A CN 113759139A
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- liquid
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- liquid storage
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
Abstract
A sample analyzer and a liquid supply method thereof are provided, the sample analyzer comprises a liquid supply component, a driving component, a sampling component, a reaction component, a detection component, a waste liquid treatment component and a controller; the liquid supply assembly comprises a first liquid storage tank, a second liquid storage tank and a liquid using assembly, the first liquid storage tank is communicated with the liquid using assembly to supply liquid for the liquid using assembly, the second liquid storage tank is communicated with the liquid using assembly, and when liquid in the first liquid storage tank is insufficient, the second liquid storage tank supplies liquid for the liquid using assembly. Through setting up first liquid reserve tank and second liquid reserve tank, first liquid reserve tank supplies liquid for using the liquid subassembly, when the liquid of first liquid reserve tank is not enough, uses the second liquid reserve tank to supply liquid for using the liquid subassembly, realizes supplying liquid in succession.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a sample analyzer and a liquid supply method thereof.
Background
In a liquid supply assembly of an existing sample analyzer, when liquid in a liquid storage tank is consumed and needs to be replenished, a generally adopted method is to switch the pressure of the liquid storage tank to negative pressure and fill the liquid in a reagent barrel into the liquid storage tank by using a pressure difference between the reagent barrel and the liquid storage tank. After the filling is finished, the liquid storage tank is switched to positive pressure again, and liquid is supplied to the outside. In the process of filling liquid into the liquid storage pool, the liquid cannot be continuously supplied to the outside due to the negative pressure in the liquid storage pool, so that the pipeline needing the liquid in the sample analyzer is forced to stop working, and the working efficiency of the sample analyzer is reduced.
Disclosure of Invention
In view of the above, an object of the present invention is to provide a sample analyzer capable of continuously supplying liquid and a liquid supply method thereof.
In order to realize the purpose of the invention, the invention provides the following technical scheme:
in a first aspect, the present invention provides a sample analyzer, including a liquid supply assembly, a driving assembly, a sampling assembly, a reaction assembly, a detection assembly, a waste liquid treatment assembly, and a controller; the liquid supply assembly is used for supplying liquid; the drive assembly is used for driving a flow path in the sample analyzer; the sampling assembly is used for collecting and distributing biological samples; the reaction component is used for processing the biological sample to form a liquid to be detected; the detection assembly is used for detecting the liquid to be detected to form detection information; the waste liquid treatment component is used for collecting and discharging waste liquid in the sample analyzer; the controller is used for controlling the work flow of the sample analyzer and processing the detection information to form an analysis result;
the liquid supply assembly comprises a first liquid storage tank, a second liquid storage tank and a liquid using assembly, the first liquid storage tank is communicated with the liquid using assembly to supply liquid for the liquid using assembly, the second liquid storage tank is communicated with the liquid using assembly, and when liquid in the first liquid storage tank is insufficient, the second liquid storage tank supplies liquid for the liquid using assembly.
And a first switching piece is arranged between the second liquid storage tank and the liquid using assembly and is used for communicating or cutting off the second liquid storage tank and the liquid using assembly.
The first switching piece is further arranged between the first liquid storage tank and the liquid using assembly and used for communicating or cutting off the first liquid storage tank or the second liquid storage tank and the liquid using assembly.
The first switching piece comprises a third valve and a fourth valve, the third valve is arranged between the first liquid storage tank and the liquid using assembly, the fourth valve is arranged between the second liquid storage tank and the liquid using assembly, and the third valve and the fourth valve are used for being communicated or cut off.
Wherein the third valve and/or the fourth valve is a one-way valve, allowing the liquid in the first reservoir or the second reservoir to flow into the liquid using component, and preventing the reverse flow.
The liquid supply assembly further comprises a reagent barrel and a fourth switching piece, the reagent barrel is connected to the first liquid storage pool through the fourth switching piece, and the fourth switching piece is used for communicating or cutting off the reagent barrel and the first liquid storage pool.
Wherein the reagent barrel is further connected to the second reservoir through the fourth switch.
The fourth switching piece comprises a first valve and a second valve, the first valve is arranged between the first liquid storage tank and the reagent barrel, the second valve is arranged between the second liquid storage tank and the reagent barrel, and the first valve and the second valve are both used for communication or cut-off.
Wherein the first valve and the second valve are one-way valves allowing the liquid of the reagent barrel to flow into the first reservoir or the second reservoir while preventing reverse flow.
And a fifth switching part is arranged between the fourth switching part and the reagent barrel and is used for communicating or cutting off the reagent barrel and the fourth switching part so as to prevent the liquid of the fourth switching part from leaking and flowing into the reagent barrel.
The liquid supply assembly further comprises a first positive pressure source and a first negative pressure source which are connected with the first liquid storage tank; when the first liquid storage tank supplies liquid for the liquid using assembly, the first positive pressure source pressurizes the first liquid storage tank; when the liquid in the first liquid storage tank is insufficient for filling, the first negative pressure source is used for reducing the pressure of the liquid storage tank.
When the first liquid storage tank is filled with liquid, the second positive pressure source pressurizes the second liquid storage tank so that the second liquid storage tank supplies liquid to the liquid using assembly; when the first liquid storage tank supplies liquid to the second liquid storage tank and the second liquid storage tank supplies liquid to the liquid using assembly, the second liquid storage tank is communicated to the closed end.
The liquid supply assembly further comprises a third switching piece, the third switching piece is arranged between the second positive pressure source and the closed end and the second liquid storage tank, and the third switching piece is used for communicating or cutting off the connection between the second liquid storage tank and the second positive pressure source or the closed end.
The liquid supply assembly further comprises a seventh switching piece and a second negative pressure source or an atmosphere end, the seventh switching piece is connected with the third switching piece, and the second positive pressure source, the closed end and the second negative pressure source or the atmosphere end are communicated with the second liquid storage tank through the seventh switching piece and the third switching piece; when the first liquid storage tank fills liquid into the second liquid storage tank, the second negative pressure source reduces the pressure of the second liquid storage tank, or the atmosphere end communicates the second liquid storage tank to the atmosphere.
A sixth switching piece is further arranged between the first liquid storage tank and the second liquid storage tank and used for communicating the first liquid storage tank with the second liquid storage tank, and the first liquid storage tank is communicated with the liquid utilization assembly through the second liquid storage tank; when the first liquid storage tank supplies liquid to the second liquid storage tank and supplies liquid to the liquid using assembly through the second liquid storage tank, the sixth switching piece is communicated with the first liquid storage tank and the second liquid storage tank; when the first liquid storage tank is filled into the second liquid storage tank, the sixth switching piece is communicated with the second liquid storage tank, and the first switching piece cuts off the second liquid storage tank and the liquid using assembly; when the first liquid storage tank is filled and the second liquid storage tank supplies liquid for the liquid using assembly, the sixth switching piece cuts off the first liquid storage tank and the second liquid storage tank.
Wherein the first reservoir is larger in volume than the second reservoir.
In a second aspect, an embodiment of the present invention further provides a liquid supply method for a sample analyzer, including:
the first liquid storage tank supplies liquid for the liquid using assembly;
and when the liquid in the first liquid storage tank is insufficient, the second liquid storage tank is used for supplying liquid to the liquid using assembly.
Wherein, when the liquid in the first liquid storage pool is insufficient, the step of filling the liquid in the first liquid storage pool is carried out, and the step comprises the following steps:
and communicating the first liquid storage tank with a reagent barrel, and decompressing the first liquid storage tank by a first negative pressure source so as to enable liquid in the reagent barrel to flow into the first liquid storage tank under the action of pressure difference.
Wherein, the step that the second liquid storage tank supplies liquid for the liquid using component comprises the following steps:
the first switching piece communicates the second liquid storage tank with the liquid using component, and a second positive pressure source pressurizes the second liquid storage tank so that liquid in the second liquid storage tank flows into the liquid using component.
When the first liquid storage tank is filled with liquid and the second liquid storage tank is used for supplying liquid to the liquid using assembly, the first liquid storage tank and the liquid using assembly are cut off by a first switching piece, and the second liquid storage tank and the liquid using assembly are communicated by the first switching piece.
When the first liquid storage tank is filled with liquid and the second liquid storage tank supplies liquid for the liquid using assembly, the connection between the first liquid storage tank and the second liquid storage tank is cut off by the sixth switching piece.
Wherein, the step of supplying liquid for the liquid using component by the first liquid storage tank comprises the following steps:
first switching piece intercommunication first liquid reserve tank with the liquid subassembly, first switching piece cuts off the second liquid reserve tank with the liquid subassembly, first positive pressure source is first liquid reserve tank pressure boost.
Wherein when the liquid in the second liquid storage pool is insufficient, the liquid supply method further comprises:
the sixth switching piece intercommunication first liquid reserve tank with the second liquid reserve tank, first switching piece cut off the second liquid reserve tank with the liquid subassembly, first positive pressure source is first liquid reserve tank pressure boost, and the second negative pressure source is the second liquid reserve tank decompression makes first liquid reserve tank to second liquid reserve tank perfusion liquid.
Wherein when the liquid in the first liquid storage tank and the second liquid storage tank is sufficient, the liquid supply method further comprises:
the sixth switching piece is communicated with the first liquid storage tank and the second liquid storage tank, the first liquid storage tank supplies liquid to the second liquid storage tank, meanwhile, the second liquid storage tank supplies liquid to the liquid using assembly, and the liquid level of the liquid in the second liquid storage tank does not drop.
Wherein the liquid supply method further comprises:
the first positive pressure source pressurizes the first liquid storage tank, and the closed end seals the second liquid storage tank, so that the pressure in the second liquid storage tank is constant.
Wherein the liquid supply method further comprises:
the sixth switching piece is communicated with the first liquid storage tank and the second liquid storage tank, the first positive pressure source pressurizes the first liquid storage tank, the second liquid storage tank is communicated to the atmosphere through an atmosphere end, and the second liquid storage tank and the liquid using assembly are cut off by the first switching piece.
According to the sample analyzer provided by the invention, the first liquid storage tank and the second liquid storage tank are arranged, the first liquid storage tank supplies liquid for the liquid using component, and when the liquid in the first liquid storage tank is insufficient, the second liquid storage tank supplies liquid for the liquid using component, so that continuous liquid supply is realized.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a schematic view of a liquid supply assembly of a sample analyzer according to an embodiment of the present invention.
FIG. 2 is a schematic view of a liquid supply assembly of another sample analyzer provided by an embodiment of the invention.
FIG. 3 is a schematic view of a liquid supply assembly of another sample analyzer provided by an embodiment of the invention.
FIG. 4 is a schematic view of a liquid supply assembly of another sample analyzer provided by an embodiment of the invention.
FIG. 5 is a schematic view of a liquid supply assembly of another sample analyzer provided in accordance with an embodiment of the present invention.
FIG. 6 is a schematic view of a liquid supply assembly of another sample analyzer provided by an embodiment of the invention.
FIG. 7 is a schematic view of a liquid supply assembly of another sample analyzer provided by an embodiment of the invention.
FIG. 8 is a schematic view of a liquid supply assembly of another sample analyzer provided in accordance with an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
The embodiment of the invention provides a sample analyzer. The sample analyzer may be used to perform biological sample analysis, and the biological sample may be blood, urine, or the like.
The sample analyzer comprises a liquid supply assembly, a driving assembly, a sampling assembly, a reaction assembly, a detection assembly, a waste liquid treatment assembly and a controller. The liquid supply assembly is used for supplying liquid to the sample analyzer. The drive assembly is used to drive various flow paths (including gas and liquid paths) in the sample analyzer. The driving assembly comprises a plurality of air storage tanks and an air pump, positive pressure and negative pressure are respectively established in the air pump in the air storage tanks, and the positive pressure and the negative pressure are used for realizing driving. The sampling assembly is used to collect and dispense biological samples. The sampling assembly includes a sampling needle. The reaction assembly is used for processing the biological sample to form a liquid to be detected. The reaction assembly includes a plurality of reaction cells or flow chambers. The detection component is used for detecting the liquid to be detected to form detection information. The detection assembly includes a flow cell. The waste liquid treatment assembly is used for collecting and discharging waste liquid in the sample analyzer. The controller is used for controlling the work flow of the sample analyzer and processing the detection information to form an analysis result.
Referring to fig. 1 and 5, a liquid supply assembly of the sample analyzer according to an embodiment of the present invention includes a first liquid storage tank 1, a second liquid storage tank 2, and a liquid using assembly 3, wherein the first liquid storage tank 1 is communicated with the liquid using assembly 3 to supply liquid to the liquid using assembly 3, the second liquid storage tank 2 is communicated with the liquid using assembly 3, and when the liquid in the first liquid storage tank 1 is insufficient, the second liquid storage tank 2 supplies liquid to the liquid using assembly 3.
In this embodiment, through setting up first liquid reserve tank 1 and second liquid reserve tank 2, first liquid reserve tank 1 supplies liquid for using liquid subassembly 3, and when the liquid of first liquid reserve tank 1 was not enough, use second liquid reserve tank 2 to supply liquid for using liquid subassembly 3, realizes supplying liquid in succession.
It should be understood that the first fluid reservoir 1 of the present embodiment may be in direct communication with the fluid consuming assembly 3, as shown in fig. 1, or in indirect communication, as shown in fig. 5, wherein the first fluid reservoir 1 is in communication with the fluid consuming assembly through the second fluid reservoir 2.
In one embodiment, referring to fig. 1, a first liquid storage tank 1 and a second liquid storage tank 2 are arranged in parallel, and when the first liquid storage tank 1 is filled with insufficient liquid, the second liquid storage tank 2 is used for supplying liquid to a liquid using assembly 3; when the liquid in the second liquid storage tank 2 is insufficient and is filled, the first liquid storage tank 1 is used for supplying liquid to the liquid using assembly 3, so that the liquid using assembly 3 can be supplied with liquid all the time, and continuous liquid supply is realized.
Optionally, the first reservoir 1 and the second reservoir 2 have the same shape and structure, and have the same volume, which facilitates manufacture and spare parts of parts.
Alternatively, the liquid using module 3 may be a reaction module or a detection module. For example, the use solution module 1 may be a reaction cell or a flow cell. The first reservoir 1 and the second reservoir 2 may be used for storing a dilution liquid.
Optionally, a first liquid level sensor is arranged in the first liquid storage tank 1 and used for detecting the liquid level in the first liquid storage tank 1. A second liquid level sensor is arranged in the second liquid storage tank 2 and used for detecting the liquid level in the second liquid storage tank 2. The first and second level sensors may be float sensors.
In one embodiment, a first switch 41 is disposed between the first liquid storage tank 1 and the second liquid storage tank 2 and the liquid using component 3, the first liquid storage tank 1 is connected to the liquid using component 3 through the first switch 41, the second liquid storage tank 2 is connected to the liquid using component 3 through the first switch 41, and the first switch 3 is used for switching the connection state of the first liquid storage tank 1 or the second liquid storage tank 2 and the liquid using component 3. In other words, the first switch 41 is used to connect or disconnect the first reservoir 1 and the fluid module 3, the first switch 41 is also used to connect or disconnect the second reservoir 2 and the fluid module 3, and the first reservoir 1 and the second reservoir 2 are not connected or disconnected at the same time, but are crossed. Namely, when the first switching member 41 is communicated with the first liquid storage tank 1 and the liquid using component 3, the second liquid storage tank 2 and the liquid using component 3 are cut off; when the first switch 41 communicates the second reservoir 2 and the fluid module 3, the first reservoir 1 and the fluid module 3 are cut off.
In this embodiment, when the first switching member 41 communicates the first liquid storage tank 1 with the liquid consuming assembly 3, the first liquid storage tank 1 is used for supplying liquid to the liquid consuming assembly 3, at this time, the first switching member 41 cuts off the connection between the second liquid storage tank 2 and the liquid consuming assembly 3, and the second liquid storage tank 2 can be filled. When the first switching piece 41 is communicated with the second liquid storage tank 2 and the liquid using component 3, the second liquid storage tank 2 is used for supplying liquid to the liquid using component 3, at the moment, the first switching piece 41 cuts off the connection between the first liquid storage tank 1 and the liquid using component 3, and the first liquid storage tank 1 can be filled. The first switch member 41 may be a single two-position three-way solenoid valve or two shut-off valves.
In one embodiment, a first positive pressure source 12 and a first negative pressure source 13 are connected to the first reservoir 1, and a second positive pressure source 22 and a second negative pressure source 23 are connected to the second reservoir 2. The first positive pressure source 12 is used for pressurizing the first liquid storage tank 1, so that the liquid in the first liquid storage tank 1 flows to the liquid using component 3 under the action of pressure; the first negative pressure source 13 is used for depressurizing the first liquid reservoir 1 so that the pressure in the first liquid reservoir 1 is lower than the external pressure (e.g., atmospheric pressure), and the first liquid reservoir 1 has suction force for filling the first liquid reservoir 1 with liquid. Similarly, a second positive pressure source 22 is used to supply the second reservoir 2 with liquid to the liquid using assembly 3, and a second negative pressure source 23 is used to fill the second reservoir 2 with liquid.
Optionally, a second switching member 11 is disposed between the first positive pressure source 12 and the first negative pressure source 13 and the first reservoir 1, and the second switching member 11 is used to switch the connection state of the first reservoir 1 and the first positive pressure source 12 or the first negative pressure source 13.
Specifically, when the second switching member 11 communicates the first positive pressure source 12 with the first reservoir 1, the first negative pressure source 13 is disconnected from the first reservoir 1; when the second switching member 11 connects the first negative pressure source 13 and the first reservoir 1, the first positive pressure source 12 and the first reservoir 1 are disconnected. The second switch 11 may be a single two-position three-way solenoid valve or two shut-off valves.
Optionally, a third switching member 21 is disposed between the second positive pressure source 22 and the second negative pressure source 23 and the second reservoir 2, and the third switching member 21 is configured to switch a connection state between the second reservoir 2 and the second positive pressure source 22 or the second negative pressure source 23.
Specifically, when the third switching member 21 communicates the second positive pressure source 22 with the second reservoir 2, the second negative pressure source 23 is disconnected from the second reservoir 2; when the third switching member 21 communicates the second negative pressure source 23 and the second reservoir 2, the second positive pressure source 22 and the second reservoir 2 are disconnected. The third switch 21 may be a single two-position three-way solenoid valve or two shut-off valves.
In one embodiment, the liquid supply assembly further comprises a reagent barrel 5, the reagent barrel 5 being connected to the first reservoir 1 and the second reservoir 2. When the first liquid storage tank 1 is communicated with the first negative pressure source 13 or the second liquid storage tank 2 is communicated with the second negative pressure source 23, the reagent barrel 5 fills liquid into the first liquid storage tank 1 or the second liquid storage tank 2, namely, the liquid in the reagent barrel 5 enters the first liquid storage tank 1 or the second liquid storage tank 2 under the action of pressure difference.
Optionally, a fourth switching member 42 is disposed between the first liquid storage tank 1 and the second liquid storage tank 2 and the reagent barrel 5, and the fourth switching member 42 is used for switching a connection state between the reagent barrel 5 and the first liquid storage tank 1 or the second liquid storage tank 2.
Specifically, when the fourth switching member 42 connects the first reservoir 1 and the reagent bucket 5, the second reservoir 2 and the reagent bucket 5 are cut off; when the fourth switching member 42 communicates the second reservoir 2 and the reagent bucket 5, the first reservoir 1 and the reagent bucket 5 are cut off.
In this embodiment, the fourth switching member 42 includes a first valve 421 and a second valve 422. The first valve 421 is arranged between the first liquid storage tank 1 and the reagent barrel 5 and used for communication or cut-off; the second valve 422 is disposed between the second reservoir 2 and the reagent barrel 5 for communication or cutoff. The first valve 421 and the second valve 422 may be shut-off valves.
Preferably, a first three-way joint 423 is provided between the first valve 421, the second valve 422 and the reagent barrel 5, such that the first valve 421 is disposed between the first reservoir 1 and the first three-way joint 423, the second valve 422 is disposed between the second reservoir 2 and the first three-way joint 423, and the first three-way joint 423 is used for distributing the liquid of the reagent barrel 5 to the first valve 421 and the second valve 422.
In one embodiment, referring to fig. 2, the first switch 41 includes a third valve 411 and a fourth valve 412. The third valve 411 is arranged between the first liquid storage tank 1 and the liquid using assembly 3 and used for communication or cut-off; a fourth valve 412 is provided between the second reservoir 2 and the fluid consuming assembly 3 for communication or disconnection.
Specifically, when the third valve 411 communicates the first reservoir 1 and the liquid consuming set 3, the fourth valve 412 shuts off the second reservoir 2 and the liquid consuming set 3; when the fourth valve 412 communicates the second reservoir 2 and the liquid consuming set 3, the third valve 411 shuts off the first reservoir 1 and the liquid consuming set 3.
In this embodiment, the third valve 411 and the fourth valve 412 are one-way valves, which allow the liquid in the first liquid storage tank 1 or the second liquid storage tank 2 to flow into the liquid using assembly 3, but cannot flow in the opposite direction, so as to prevent the liquid in the liquid using assembly 3 from contaminating the first liquid storage tank 1 or the second liquid storage tank 2.
Preferably, a second three-way joint 413 is arranged between the third valve 411, the fourth valve 412 and the fluid consuming assembly 3, and the second three-way joint 413 is used for communicating the fluid of the third valve 411 or the fourth valve 412 to the fluid consuming assembly 3.
In one embodiment, with reference to fig. 2, the first valve 421 and/or the second valve 422 of the fourth switching member 42 are/is a one-way valve, and the first valve 421 allows the liquid in the reagent barrel 5 to flow into the first reservoir 1 but not to flow in the reverse direction; the second valve 422 allows the liquid of the reagent barrel 5 to flow into the second reservoir 2 without flowing in the reverse direction. The adoption of the one-way valve can reduce the cost.
In this embodiment, a first three-way joint 423 may also be provided between the first valve 421 and the second valve 422 and the reagent barrel 5, such that the first valve 421 is disposed between the first reservoir 1 and the first three-way joint 423, the second valve 422 is disposed between the second reservoir 2 and the first three-way joint 423, and the first three-way joint 423 is used for distributing the liquid of the reagent barrel 5 to the first valve 421 and the second valve 422.
In one embodiment, referring to fig. 3, a fifth switch 51 is disposed between the first valve 421 and the second valve 422 and the reagent barrel 5, and the fifth switch 51 is used for connecting or disconnecting the first valve 421 and the second valve 422 to the reagent barrel 5.
Preferably, the fifth switching member 51 is disposed between the first three-way joint 423 and the reagent tank 5. When the first valve 421 and/or the second valve 422 are one-way valves, in order to prevent the first valve 421 and/or the second valve 422 from possible liquid leakage in the reverse direction, the fifth switch 51 can be switched to a state of disconnecting the first valve 421 and the second valve 422 from the reagent barrel 5, so that the liquid in the first reservoir 1 and/or the second reservoir 2 does not flow back into the reagent barrel 5 to cause contamination. The fifth switch member 51 is preferably a two-way solenoid valve.
In one embodiment, referring to fig. 4, the fourth switch 42 is a single two-position three-way valve, the first liquid storage tank 1, the second liquid storage tank 2 and the reagent barrel 5 are all connected to the fourth switch 42, and the fourth switch 42 is used for connecting or disconnecting the connection state of the reagent barrel 5 with the first liquid storage tank 1 and/or the second liquid storage tank 2.
In this embodiment, a fifth switching member 51 is provided between the fourth switching member 42 and the reagent bucket 5, and the fifth switching member 51 is a check valve that allows the liquid of the reagent bucket 5 to flow toward the fourth switching member 42 without flowing in the reverse direction.
In one embodiment, referring to fig. 5, the first reservoir 1 is connected to the second reservoir 2, and the second reservoir 2 is connected to the liquid component 3. The liquid in the first liquid storage tank 1 flows into the second liquid storage tank 2 and then flows into the liquid using component 3, so that continuous liquid supply is realized.
Preferably, the first reservoir 1 is larger in volume than the second reservoir 2, which saves space.
Preferably, a first switch 41 is also provided between the second reservoir 2 and the fluid consuming assembly 3, and the first switch 41 is used for connecting or disconnecting the second reservoir 2 and the fluid consuming assembly 3. When the liquid in the second liquid storage tank 2 is insufficient, the first switching piece 41 is arranged to cut off the second liquid storage tank 2 and the liquid using component 3, and the first liquid storage tank 1 is used for filling the second liquid storage tank 2; when the liquid in the second liquid storage tank 2 is sufficient, the first switching member 41 is opened again to continue the liquid supply.
Preferably, a sixth switching member 43 is arranged between the first liquid storage tank 1 and the second liquid storage tank 2, and the sixth switching member 43 is used for communicating or cutting off the first liquid storage tank 1 and the second liquid storage tank 2. When the liquid in the first liquid storage tank 1 and the liquid in the second liquid storage tank 2 are sufficient, the sixth switching piece 43 is communicated with the first liquid storage tank 1 and the second liquid storage tank 2, the first switching piece 41 is communicated with the second liquid storage tank 2 and the liquid using component 3, the liquid in the first liquid storage tank 1 flows into the second liquid storage tank 2, the liquid in the second liquid storage tank 2 flows into the liquid using component 3, so that continuous liquid supply is maintained, and the liquid in the second liquid storage tank 2 is kept sufficient. After supplying liquid for a period of time, the liquid in the first liquid storage tank 1 is not enough, then the sixth switching piece 43 cuts off the first liquid storage tank 1 and the second liquid storage tank 2, the first liquid storage tank 1 is filled, meanwhile, the first switching piece 41 continues to communicate the second liquid storage tank 2 and the liquid using component 3, and the second liquid storage tank 2 supplies liquid for the liquid using component 3. When the liquid of second liquid reserve tank 2 is not enough, first switching piece 41 cuts off second liquid reserve tank 2 and with liquid subassembly 3, and the sixth switching piece 43 intercommunication first liquid reserve tank 1 and second liquid reserve tank 2, first liquid reserve tank 1 pours into second liquid reserve tank 2. Because in the process of supplying liquid alone at second liquid storage tank 2, first liquid storage tank 1 is filling, waits that second liquid storage tank 2 supplies liquid after a period, first liquid storage tank 1 is filled and liquid is sufficient, can be used for filling to second liquid storage tank 2. When the first reservoir 1 is filled into the second reservoir 2, the working gap of the liquid consuming assembly 3 can be selected, so that the liquid consuming of the liquid consuming assembly 3 can be unaffected.
In one embodiment, a first positive pressure source 12 and a first negative pressure source 13 are connected to the first reservoir 1, the first positive pressure source 12 is configured to pressurize the first reservoir 1, and the first negative pressure source 13 is configured to depressurize the first reservoir 1. When the first liquid storage tank 1 supplies liquid or fills liquid into the second liquid storage tank 2, the first positive pressure source 12 pressurizes the first liquid storage tank 1; when the first reservoir 1 is filled, the first negative pressure source 13 depressurizes the first reservoir 1.
Preferably, a second switching member 11 may be provided between the first positive pressure source 12 and the first negative pressure source 13 and the first reservoir 1, and the second switching member 11 is used to switch the connection state of the first reservoir 1 with the first positive pressure source 12 or the first negative pressure source 13, that is, to connect or disconnect them.
In one embodiment, a second positive pressure source 22 and a second negative pressure source 23 are connected to the second reservoir 2, the second positive pressure source 22 being adapted to pressurize the second reservoir 2 and the second negative pressure source 23 being adapted to depressurize the second reservoir 2. When the first liquid storage tank 1 is filled and the second liquid storage tank 2 is used for supplying liquid, the second positive pressure source 22 pressurizes the second liquid storage tank 2; when the second liquid storage tank 2 is filled, the first positive pressure source 12 is used for pressurizing the first liquid storage tank 1, the second negative pressure source 23 is used for depressurizing the second liquid storage tank 2, so that the liquid in the first liquid storage tank 1 can be filled into the second liquid storage tank 2 in an accelerated manner, the liquid can be supplied after the second liquid storage tank is filled rapidly, and the purpose of supplying liquid at short time intervals is achieved.
Preferably, a third switching member 21 may be provided between the second positive pressure source 22 and the second negative pressure source 23 and the second reservoir 2, and the third switching member 21 may be used to switch the connection state of the second reservoir 2 with the second positive pressure source 22 or the second negative pressure source 23, that is, to connect or disconnect them.
In this embodiment, the second reservoir 2 is further connected to a closed end 25, and the closed end 25 keeps the pressure in the second reservoir 2 constant. When the first liquid storage tank 1 is used for supplying liquid to the second liquid storage tank 2, and the second liquid storage tank 2 supplies liquid to the liquid using assembly 3, the second liquid storage tank 2 is connected with the closed end 25 to keep the pressure in the second liquid storage tank 2 unchanged, so that the liquid level in the second liquid storage tank 2 is kept at a certain height without reduction.
Preferably, a seventh switching member 24 is provided between the closed end 25 and the third switching member 21 and the second reservoir 2, and the seventh switching member 24 is used to switch the connection state of the second reservoir 2 with the closed end 25 or the second positive pressure source 22/the second negative pressure source 23.
Specifically, when the first liquid storage tank 1 supplies liquid to the second liquid storage tank 2 and the second liquid storage tank 2 supplies liquid to the liquid using assembly 3, the seventh switching member 24 is switched to the second liquid storage tank 2 to be communicated with the closed end 25; when the first liquid storage tank 1 is filled and the second liquid storage tank 2 supplies liquid to the liquid using component 3, the seventh switching piece 24 is switched to the second liquid storage tank 2 to be communicated with the third switching piece 21, and the third switching piece 21 is switched to be communicated with the second positive pressure source 22, so that the second positive pressure source 22 pressurizes the second liquid storage tank 2; when the first liquid storage tank 1 is filled into the second liquid storage tank 2, the seventh switching member 24 is switched to communicate the second liquid storage tank 2 with the third switching member 21, and the third switching member 21 is switched to communicate with the second negative pressure source 23, so that the second negative pressure source 23 is depressurized by the second liquid storage tank 2. The seventh switch 24 may be a single two-position three-way valve or two solenoid valves.
It should be understood that the second positive pressure source 22, the second negative pressure source 23/atmosphere end 26 and the closed end 25 are connected to the second reservoir 2 through the seventh switching member 24 and the third switching member 21, and the connection positions of the second positive pressure source 22, the second negative pressure source 23/atmosphere end 26 and the closed end 25 on the seventh switching member 24 and the third switching member 21 are freely arranged, for example, as shown in fig. 5, the third switching member 21 is connected to the closed end 25, and the seventh switching member 24 is connected to the second positive pressure source 22 and the second negative pressure source 23; as also shown in fig. 7, the third switching member 21 is connected to the second positive pressure source 22, and the seventh switching member 24 is connected to the closed end 25 and the atmosphere end 26.
In one embodiment, the first reservoir 1 is further connected to a reagent barrel 5, and the reagent barrel 5 is used for supplying liquid to the first reservoir 1 when the first reservoir 1 is in a filling state.
Preferably, a fourth switching member 42 is disposed between the first reservoir 1 and the reagent barrel 5, and the fourth switching member 42 is used for connecting or disconnecting the fourth switching member 42 and the reagent barrel 5. In this embodiment, the fourth switching member 42 is a shutoff valve.
In one embodiment, referring to fig. 6, the sixth switching member 43 is a one-way valve, and the sixth switching member 43 is used for connecting or disconnecting the first reservoir 1 and the second reservoir 2, and only allows the liquid in the first reservoir 1 to flow into the second reservoir 2, but not to flow in the reverse direction.
In one embodiment, the fourth switching member 42 is also a one-way valve, and the fourth switching member 42 is used to connect or disconnect the first reservoir 1 and the reagent barrel 5, and allows only the liquid of the reagent barrel 1 to flow into the first reservoir 1, but not to flow in the reverse direction.
In one embodiment, referring to fig. 7, the third switch 21 is disposed between the second positive pressure source 22 and the seventh switch 24 and the second reservoir 2, that is, the third switch 21 is used to connect or disconnect the second reservoir 2 and the second positive pressure source 22, and is also used to connect or disconnect the second reservoir 2 and the seventh switch 24. The seventh switching member 24 is disposed between the closed end 25 and the atmosphere end 26 and the third switching member 21, that is, the seventh switching member 24 is used to communicate or disconnect the closed end 25 and the third switching member 21 and also to communicate or disconnect the atmosphere end 26 and the third switching member 21. The third switching member 21 and the seventh switching member 24 are both two-position three-way valves.
In this embodiment, when the first liquid storage tank 1 supplies liquid to the second liquid storage tank 2 and the second liquid storage tank 2 supplies liquid to the liquid using assembly 3, the third switch 21 is connected to the seventh switch 24, and the seventh switch 24 is connected to the closed end 25, so as to keep the pressure in the second liquid storage tank 2 unchanged. When the first reservoir 1 is filled and the second reservoir 2 supplies liquid to the liquid using assembly 3, the third switch 21 is connected to the positive pressure source 22 to pressurize the second reservoir 2. When the first reservoir 1 is filled into the second reservoir 2, the third switch 21 is connected to the seventh switch 24, and the seventh switch 24 is connected to the atmosphere port 26, so that the pressure in the second reservoir 2 is atmospheric pressure. Filling can also be achieved with a pressure in the second reservoir 2 that is at atmospheric pressure, but only slightly slower, relative to a pressure in the second reservoir 2 that is at negative pressure.
In one embodiment, referring to fig. 8, the third switch 21 is disposed between the second positive pressure source 22 and the seventh switch 24 and the second reservoir 2, that is, the third switch 21 is used for connecting or disconnecting the second positive pressure source 22 and the second reservoir 2, and for connecting or disconnecting the seventh switch 24 and the second reservoir 2. The seventh switch 24 is provided between the atmosphere end 26 and the third switch 21, i.e., for communicating or shutting off the atmosphere end 26 and the third switch 21. The third switch 21 is a two-position three-way valve. The seventh switching member 24 is a two-way valve, one port is connected to the atmosphere port 26, and the other port is closed, and when the seventh switching member 24 needs to be communicated to the closed end 25 (see fig. 7), the seventh switching member 24 is communicated to the closed port, and the same effect as that of communicating the closed end 25 is also achieved.
It is understood that in the embodiment of the present invention, the filling and feeding actions of the first and second reservoirs 1 and 2 are realized by precisely controlling the liquid consumption amount therein, the state of the liquid level sensor therein, and the filling time. The basic principle is as follows: A. the consumption amount of the liquid in the first reservoir 1 and the second reservoir 2 (i.e., the liquid supply amount of the first reservoir 1 and the second reservoir 2) for each function sequence should be smaller than the total amount of the filled state of the first reservoir 1 and the second reservoir 2, for example, the total amount is 140mL and the consumption amount is 120 mL. B. Each functional sequence, if the liquid in the first reservoir 1 or the second reservoir 2 is consumed, must be filled before the sequence is completed. C. In every function time sequence, the opportunity of filling, first stock solution pond 1 and second stock solution pond 2 are supplied liquid and fill separately and go on, owing to set up two stock solutions, can first stock solution pond 1 when filling, second stock solution pond 2 supplies liquid, perhaps first stock solution pond 1 supplies liquid, second stock solution pond 2 supplies liquid, can also first stock solution pond 1 supplies liquid for second stock solution pond 2 to reduce instrument measurement and maintenance consuming time by a wide margin, improve the flexibility of time sequence action arrangement.
Referring to fig. 1 and fig. 5, a liquid supply method for a sample analyzer is further provided in an embodiment of the present invention, and the liquid supply method can use the sample analyzer provided in the above embodiment to supply liquid. The liquid supply method can be used for the sample analyzer provided in the above embodiments.
The liquid supply method comprises the following steps:
the first liquid storage tank 1 is used for supplying liquid to the liquid using component 3;
when the liquid in the first liquid storage tank 1 is insufficient, the second liquid storage tank 2 is used for supplying liquid to the liquid using component 3.
In this embodiment, the first liquid storage tank 1 is used to supply liquid to the liquid using assembly 3, and when the liquid in the first liquid storage tank 1 is insufficient, the second liquid storage tank 2 is used to supply liquid to the liquid using assembly 3, so that continuous liquid supply is realized.
In one embodiment, referring to fig. 1, when the first reservoir 1 is short of liquid, the step of filling the first reservoir 1 with liquid includes:
the first liquid storage tank 1 is communicated with the reagent barrel 5, and the first negative pressure source 13 reduces the pressure of the first liquid storage tank 1 so that the liquid in the reagent barrel 5 flows into the first liquid storage tank 1 under the action of pressure difference.
Further, referring to fig. 1 or fig. 5, the first reservoir 1 and the reagent barrel 5 are communicated by the fourth switch 42, and the fourth switch 42 can also cut off the first reservoir 1 and the reagent barrel 5.
Further, referring to fig. 1, the fourth switching member 42 may further communicate the second liquid storage tank 2 and the reagent barrel 5, so that the reagent barrel 5 may also fill the second liquid storage tank 2 with liquid.
In one embodiment, referring to fig. 1 or fig. 5, the step of supplying the liquid from the liquid component 3 to the second liquid storage tank 2 includes:
the first switching member 41 communicates the second reservoir 2 and the liquid consuming unit 3, and the second positive pressure source 22 pressurizes the second reservoir 2 so that the liquid in the second reservoir 2 flows into the liquid consuming unit 3.
In an embodiment, referring to fig. 2, when the first liquid storage tank 1 is filled with liquid and the second liquid storage tank 2 supplies liquid to the liquid consuming assembly 3, the third valve 411 of the first switch 41 cuts off the first liquid storage tank 1 and the liquid consuming assembly 3, and the fourth valve 412 connects the second liquid storage tank 2 and the liquid consuming assembly 3. Further, referring to fig. 2, the first valve 421 of the third switch 42 connects the first reservoir 1 and the reagent barrel 5, and the second valve 422 cuts off the second reservoir 2 and the reagent barrel 5.
In one embodiment, referring to fig. 5, when the first reservoir 1 is filled with liquid and the second reservoir 2 is filled with liquid from the liquid-using component 3, the sixth switch 43 cuts off the connection between the first reservoir 1 and the second reservoir 2.
In one embodiment, referring to fig. 1, the step of supplying liquid from the first liquid storage tank 1 to the liquid supply assembly 3 includes:
the third valve 411 of the first switching member 41 communicates the first reservoir 1 and the fluid consuming module 3, the fourth valve 412 shuts off the second reservoir 2 and the fluid consuming module 3, and the first positive pressure source 12 pressurizes the first reservoir 1.
In one embodiment, referring to fig. 5, when the liquid in the second liquid storage tank 2 is insufficient, the liquid supply method further includes:
the sixth switching member 43 communicates the first liquid storage tank 1 and the second liquid storage tank 2, the first switching member 41 cuts off the second liquid storage tank 2 and the liquid using assembly 3, the first positive pressure source 12 pressurizes the first liquid storage tank 1, and the second negative pressure source 23 depressurizes the second liquid storage tank 2, so that the first liquid storage tank 1 fills liquid into the second liquid storage tank 3.
In one embodiment, referring to fig. 5, when the liquid in the first liquid storage tank 1 and the second liquid storage tank 2 is sufficient, the liquid supply method further includes:
the sixth switching member 43 is communicated with the first liquid storage tank 1 and the second liquid storage tank 2, the first liquid storage tank 1 supplies liquid to the second liquid storage tank 2, meanwhile, the second liquid storage tank 2 supplies liquid to the liquid using assembly 3, and the liquid level of the liquid in the second liquid storage tank 2 does not drop.
In one embodiment, referring to fig. 5, the liquid supply method further includes:
the first positive pressure source 12 pressurizes the first reservoir 1 and the closed end 25 closes the second reservoir 2 so that the pressure in the second reservoir 2 is constant.
Further, referring to fig. 5, the step of "the second liquid storage tank 2 supplies liquid to the liquid using assembly 3" includes:
the first switching piece 41 is communicated with the second liquid storage tank 2 and the liquid using component 3, so that when liquid in the first liquid storage tank 1 enters the second liquid storage tank 2, the second liquid storage tank 2 supplies liquid to the liquid using component 3, and the liquid level of the second liquid storage tank 2 is kept not to be reduced.
In one embodiment, referring to fig. 7, the liquid supply method further includes:
the sixth switching member 43 communicates the first reservoir 1 and the second reservoir 2, the first positive pressure source 12 pressurizes the first reservoir 1, the atmosphere port 26 communicates the second reservoir 2 to the atmosphere, and the first switching member 41 cuts off the second reservoir 2 and the fluid using unit 3 so that the first reservoir 1 fills the second reservoir 2 with the fluid.
While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (26)
1. A sample analyzer is characterized by comprising a liquid supply component, a driving component, a sampling component, a reaction component, a detection component, a waste liquid treatment component and a controller; the liquid supply assembly is used for supplying liquid; the drive assembly is used for driving a flow path in the sample analyzer; the sampling assembly is used for collecting and distributing biological samples; the reaction component is used for processing the biological sample to form a liquid to be detected; the detection assembly is used for detecting the liquid to be detected to form detection information; the waste liquid treatment component is used for collecting and discharging waste liquid in the sample analyzer; the controller is used for controlling the work flow of the sample analyzer and processing the detection information to form an analysis result;
the liquid supply assembly comprises a first liquid storage tank, a second liquid storage tank and a liquid using assembly, the first liquid storage tank is communicated with the liquid using assembly to supply liquid for the liquid using assembly, the second liquid storage tank is communicated with the liquid using assembly, and when liquid in the first liquid storage tank is insufficient, the second liquid storage tank supplies liquid for the liquid using assembly.
2. The sample analyzer of claim 1, wherein a first switch is disposed between the second reservoir and the fluid consuming assembly, the first switch being configured to connect or disconnect the second reservoir and the fluid consuming assembly.
3. The sample analyzer of claim 2, wherein the first switch is further disposed between the first reservoir and the fluid consuming assembly, the first switch being configured to connect or disconnect the first reservoir or the second reservoir from the fluid consuming assembly.
4. The sample analyzer of claim 3 wherein the first switching element includes a third valve disposed between the first reservoir and the user fluid assembly and a fourth valve disposed between the second reservoir and the user fluid assembly, the third and fourth valves being operable to be connected or disconnected.
5. The sample analyzer of claim 4, wherein the third valve and/or the fourth valve is a one-way valve that allows fluid from the first reservoir or the second reservoir to flow into the fluid consuming assembly while preventing reverse flow.
6. The sample analyzer of claim 1, wherein the liquid supply assembly further comprises a reagent bucket connected to the first reservoir via a fourth switch for connecting or disconnecting the reagent bucket to the first reservoir.
7. The sample analyzer of claim 6, wherein the reagent cartridge is further connected to the second reservoir via the fourth switch.
8. The sample analyzer of claim 7, wherein the fourth switch includes a first valve and a second valve, the first valve disposed between the first reservoir and the reagent barrel, the second valve disposed between the second reservoir and the reagent barrel, the first valve and the second valve both for communication or disconnection.
9. The sample analyzer of claim 8, wherein the first valve and the second valve are one-way valves that allow fluid from the reagent cartridge to flow into the first reservoir or the second reservoir while preventing reverse flow.
10. The sample analyzer of claim 7, wherein a fifth switch is further provided between the fourth switch and the reagent bucket, the fifth switch being configured to connect or disconnect the reagent bucket and the fourth switch to prevent the liquid of the fourth switch from leaking and flowing into the reagent bucket.
11. The sample analyzer of claim 1, wherein the liquid supply assembly further comprises a first positive pressure source and a first negative pressure source connected to the first reservoir; when the first liquid storage tank supplies liquid for the liquid using assembly, the first positive pressure source pressurizes the first liquid storage tank; when the liquid in the first liquid storage tank is insufficient for filling, the first negative pressure source is used for reducing the pressure of the liquid storage tank.
12. The sample analyzer of claim 11 wherein the liquid supply assembly further comprises a second positive pressure source connected to the second reservoir and a closed end, the second positive pressure source pressurizing the second reservoir to supply liquid from the second reservoir to the liquid usage assembly when the first reservoir is filled with liquid; when the first liquid storage tank supplies liquid to the second liquid storage tank and the second liquid storage tank supplies liquid to the liquid using assembly, the second liquid storage tank is communicated to the closed end.
13. The sample analyzer of claim 12 wherein the liquid supply assembly further comprises a third switch disposed between the second positive pressure source and the closed end and the second reservoir, the third switch for connecting or disconnecting the second reservoir to the second positive pressure source or the closed end.
14. The sample analyzer of claim 13, wherein the liquid supply assembly further comprises a seventh switch connected to the third switch and a second negative pressure source or an atmospheric end, the second positive pressure source, the closed end, and the second negative pressure source or the atmospheric end being communicated to the second reservoir through the seventh switch and the third switch; when the first liquid storage tank fills liquid into the second liquid storage tank, the second negative pressure source reduces the pressure of the second liquid storage tank, or the atmosphere end communicates the second liquid storage tank to the atmosphere.
15. The sample analyzer of claim 2, wherein a sixth switch is disposed between the first reservoir and the second reservoir, the sixth switch being configured to communicate the first reservoir with the second reservoir, the first reservoir being in communication with the fluid consuming assembly via the second reservoir; when the first liquid storage tank supplies liquid to the second liquid storage tank and supplies liquid to the liquid using assembly through the second liquid storage tank, the sixth switching piece is communicated with the first liquid storage tank and the second liquid storage tank; when the first liquid storage tank is filled into the second liquid storage tank, the sixth switching piece is communicated with the second liquid storage tank, and the first switching piece cuts off the second liquid storage tank and the liquid using assembly; when the first liquid storage tank is filled and the second liquid storage tank supplies liquid for the liquid using assembly, the sixth switching piece cuts off the first liquid storage tank and the second liquid storage tank.
16. The sample analyzer of claim 15, wherein the first reservoir is larger in volume than the second reservoir.
17. A method of supplying liquid to a sample analyzer, comprising:
the first liquid storage tank supplies liquid for the liquid using assembly;
and when the liquid in the first liquid storage tank is insufficient, the second liquid storage tank is used for supplying liquid to the liquid using assembly.
18. The liquid supply method as claimed in claim 17, wherein the step of filling the first reservoir with liquid is performed when the first reservoir is not sufficiently filled with liquid, comprising:
and communicating the first liquid storage tank with a reagent barrel, and decompressing the first liquid storage tank by a first negative pressure source so as to enable liquid in the reagent barrel to flow into the first liquid storage tank under the action of pressure difference.
19. The liquid supply method of claim 17, wherein the step of supplying liquid from the second reservoir to the liquid module comprises:
the first switching piece communicates the second liquid storage tank with the liquid using component, and a second positive pressure source pressurizes the second liquid storage tank so that liquid in the second liquid storage tank flows into the liquid using component.
20. The liquid supply method of claim 18, wherein a first switch cuts off the first reservoir from the liquid consuming assembly and the first switch communicates the second reservoir with the liquid consuming assembly when the first reservoir is filled with liquid and the second reservoir supplies liquid to the liquid consuming assembly.
21. The liquid supply method of claim 18, wherein a sixth switch disconnects the first reservoir from the second reservoir when the first reservoir is primed and the second reservoir is supplying liquid to the liquid using assembly.
22. The liquid supply method of claim 17, wherein the step of supplying liquid from the first reservoir to the liquid using assembly comprises:
first switching piece intercommunication first liquid reserve tank with the liquid subassembly, first switching piece cuts off the second liquid reserve tank with the liquid subassembly, first positive pressure source is first liquid reserve tank pressure boost.
23. The liquid supply method of claim 17, wherein when the second reservoir is deficient in liquid, the liquid supply method further comprises:
the sixth switching piece intercommunication first liquid reserve tank with the second liquid reserve tank, first switching piece cut off the second liquid reserve tank with the liquid subassembly, first positive pressure source is first liquid reserve tank pressure boost, and the second negative pressure source is the second liquid reserve tank decompression makes first liquid reserve tank to second liquid reserve tank perfusion liquid.
24. The liquid supply method of claim 17, wherein when the first reservoir and the second reservoir are sufficiently filled with liquid, the liquid supply method further comprises:
the sixth switching piece is communicated with the first liquid storage tank and the second liquid storage tank, the first liquid storage tank supplies liquid to the second liquid storage tank, meanwhile, the second liquid storage tank supplies liquid to the liquid using assembly, and the liquid level of the liquid in the second liquid storage tank does not drop.
25. The liquid supply method of claim 24, further comprising:
the first positive pressure source pressurizes the first liquid storage tank, and the closed end seals the second liquid storage tank, so that the pressure in the second liquid storage tank is constant.
26. The liquid supply method of claim 23, further comprising:
the sixth switching piece is communicated with the first liquid storage tank and the second liquid storage tank, the first positive pressure source pressurizes the first liquid storage tank, the second liquid storage tank is communicated to the atmosphere through an atmosphere end, and the second liquid storage tank and the liquid using assembly are cut off by the first switching piece.
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| CN202010485856.8A CN113759139A (en) | 2020-06-01 | 2020-06-01 | Sample analyzer and liquid supply method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114460326A (en) * | 2022-04-11 | 2022-05-10 | 深圳市帝迈生物技术有限公司 | Reagent replenishing device and reagent replenishing method for sample analyzer |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114460326A (en) * | 2022-04-11 | 2022-05-10 | 深圳市帝迈生物技术有限公司 | Reagent replenishing device and reagent replenishing method for sample analyzer |
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