CN113758980A - 经配置以接纳卡盒的读取器、电化学传感器组合件及卡盒 - Google Patents

经配置以接纳卡盒的读取器、电化学传感器组合件及卡盒 Download PDF

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Publication number
CN113758980A
CN113758980A CN202111163423.1A CN202111163423A CN113758980A CN 113758980 A CN113758980 A CN 113758980A CN 202111163423 A CN202111163423 A CN 202111163423A CN 113758980 A CN113758980 A CN 113758980A
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cartridge
reader
sample
sensor
pneumatic
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CN202111163423.1A
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Chinese (zh)
Inventor
布拉德利·N·约翰逊
杨芮明
甘尚·A·乔希
拉伊·R·拉特基
加勒特·格吕纳
谢尔盖·斯卡尔乌波
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Nanomix Inc
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Nanomix Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
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    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/4163—Systems checking the operation of, or calibrating, the measuring apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/492—Determining multiple analytes
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/27—Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a further parameter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
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  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
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  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Electrochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ecology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN202111163423.1A 2013-03-15 2014-03-14 经配置以接纳卡盒的读取器、电化学传感器组合件及卡盒 Pending CN113758980A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/844,334 2013-03-15
US13/844,334 US9458488B2 (en) 2013-03-15 2013-03-15 Point of care sensor systems
CN201480025154.4A CN105163661B (zh) 2013-03-15 2014-03-14 护理点传感器系统

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201480025154.4A Division CN105163661B (zh) 2013-03-15 2014-03-14 护理点传感器系统

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CN113758980A true CN113758980A (zh) 2021-12-07

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CN202111163423.1A Pending CN113758980A (zh) 2013-03-15 2014-03-14 经配置以接纳卡盒的读取器、电化学传感器组合件及卡盒
CN201480025154.4A Expired - Fee Related CN105163661B (zh) 2013-03-15 2014-03-14 护理点传感器系统
CN201811610367.XA Expired - Fee Related CN109991296B (zh) 2013-03-15 2014-03-14 护理点传感器系统

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CN201480025154.4A Expired - Fee Related CN105163661B (zh) 2013-03-15 2014-03-14 护理点传感器系统
CN201811610367.XA Expired - Fee Related CN109991296B (zh) 2013-03-15 2014-03-14 护理点传感器系统

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US (3) US9458488B2 (cg-RX-API-DMAC7.html)
EP (1) EP2967451B1 (cg-RX-API-DMAC7.html)
JP (1) JP6478333B2 (cg-RX-API-DMAC7.html)
CN (3) CN113758980A (cg-RX-API-DMAC7.html)
WO (1) WO2014144660A1 (cg-RX-API-DMAC7.html)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9458488B2 (en) 2013-03-15 2016-10-04 Nanomix, Inc. Point of care sensor systems
USD739553S1 (en) * 2013-03-15 2015-09-22 Nanomix, Inc. Chemical sensor cartridge
WO2015033229A2 (en) * 2013-09-04 2015-03-12 Credo Biomedical Pte Ltd. Assay test device, kit and method of using
CN106164636B (zh) * 2014-02-01 2019-10-22 埃斯梅斯公司 用于监测并且调节流体流量的芯片器件及其制造方法
US11033898B2 (en) 2014-02-01 2021-06-15 Ezmems Ltd. Fluidic microelectromechanical sensors/devices and fabrication methods thereof
EP3191844B1 (en) 2014-09-08 2022-04-20 Indian Institute Of Science Electrochemical biosensor and a method of sensing albumin and its complexes
US10001449B2 (en) 2014-12-15 2018-06-19 Church & Dwight Co., Inc. Systems, devices and methods for a hydroscopic based lateral flow assay
WO2016122705A1 (en) 2015-01-30 2016-08-04 Hewlett-Packard Development Company, L.P. Microfluidics sensing system
TWI547694B (zh) * 2015-01-30 2016-09-01 國立陽明大學 微流道生物反應器及其套組和使用方法
GB201511039D0 (en) 2015-06-23 2015-08-05 Karhiniemi Marko And Medigoo Oy And Karilahti Mika In-vitro-analyser
US9922525B2 (en) * 2015-08-14 2018-03-20 Gregory J. Hummer Monitoring system for use with mobile communication device
US11340210B2 (en) * 2020-07-11 2022-05-24 Matthew Hummer Method and devices for detecting viruses and bacterial pathogens
US11179061B1 (en) * 2020-07-11 2021-11-23 Gregory J. Hummer Method and devices for detecting viruses and bacterial pathogens
US11896372B2 (en) * 2021-05-18 2024-02-13 Matthew Hummer Device for reading, processing and transmitting test result data for pathogens or viruses in fluid test samples
JP7097306B2 (ja) 2016-06-21 2022-07-07 シーメンス ヘルシニアーズ ネイザランド ビー．ブイ． 検体検出システム及び方法
GB201615320D0 (en) * 2016-09-09 2016-10-26 Invitron Ltd Point of care platform test
EP3552015B1 (en) * 2016-12-07 2023-01-18 Radiometer Medical ApS System and method for estimating a temperature of a liquid sample
US11213819B2 (en) * 2017-01-30 2022-01-04 Noavaran Payesh Ani Salamat (AZSense) Integrated patient monitor system
CN110520728B (zh) * 2017-03-03 2022-12-06 聚合物技术系统公司 用于酶促a1c检测和定量的系统和方法
CN108686721B (zh) * 2017-04-06 2021-04-20 美康生物科技股份有限公司 用于全血样品分离检测的微流控芯片及其检测方法
US11235327B2 (en) 2017-04-07 2022-02-01 Easydx, Inc. Point of care test cartridge
US11714083B2 (en) * 2017-05-11 2023-08-01 Arizona Board Of Regents On Behalf Of Arizona State University Point-of-care apparatus and methods for analyte detections using electrochemical impedance or capacitance
US11703513B2 (en) 2017-08-07 2023-07-18 Polymer Technology Systems, Inc. Systems and methods for enzymatic A1C detection and quantification
EP3669179B1 (en) * 2017-08-17 2023-07-19 Abbott Point Of Care Inc Systems for performing optical and electrochemical assays
EP3673083B1 (en) * 2017-10-05 2022-07-13 Boehringer Ingelheim Vetmedica GmbH Analysis system with cartridge and method for testing a sample
CN111316072B (zh) * 2017-11-17 2021-12-07 美国西门子医学诊断股份有限公司 传感器组件和使用所述传感器组件的方法
IL274481B2 (en) 2017-11-20 2024-12-01 Siemens Healthcare Diagnostics Inc User interface for managing a multi-engine diagnostic environment
US11690566B2 (en) 2017-11-21 2023-07-04 MX3 Diagnostics, Inc. Saliva testing system
WO2019217560A1 (en) * 2018-05-08 2019-11-14 Inficon, Inc. Chemical analysis device and method
CN108828231A (zh) * 2018-06-21 2018-11-16 微粒云科技（北京）有限公司 一种心肺功能标志物磁微粒微流控生物芯片、检测方法
CN108845146A (zh) * 2018-06-21 2018-11-20 微粒云科技（北京）有限公司 一种用于心肌五项标志物检测的生物芯片、检测方法
WO2020023903A1 (en) 2018-07-27 2020-01-30 Zepto Life Technology, LLC System and method for gmr-based detection of biomarkers
CN109061130A (zh) * 2018-08-06 2018-12-21 张岩锐 一种带有尿液分析试纸条的装置
US10753986B2 (en) 2018-10-04 2020-08-25 Genmark Diagnostics, Inc. Systems and methods for assessing electrical connectivity between elements of assay devices
US10352983B1 (en) * 2018-10-04 2019-07-16 Genmark Diagnostics, Inc. Systems and methods for assessing electrical connectivity between elements of assay devices
CA3155751C (en) 2018-11-02 2023-07-18 Cardiai Technologies Ltd. Portable electrochemical-sensor system for analyzing user health conditions and method thereof
CN113543882A (zh) * 2018-12-31 2021-10-22 本-古里安大学B.G.内盖夫技术和应用公司 捕获流测定装置和方法
WO2020163780A1 (en) * 2019-02-07 2020-08-13 Giner, Inc. Method and system for detection and/or quantification of delta-9-tetrahydrocannabinol in saliva
US11723553B2 (en) 2019-02-11 2023-08-15 Giner, Inc. Method and system for detection and/or quantification of delta-9-tetrahydrocannabinol in exhaled breath
CN109682878B (zh) * 2019-03-01 2024-07-05 南京岚煜生物科技有限公司 一种具有五层结构的多通道微流体凝血检测芯片
WO2020223814A1 (en) * 2019-05-06 2020-11-12 University Of Prince Edward Island Portable field testing apparatus and method
US12320771B2 (en) 2019-06-12 2025-06-03 Siemens Healthcare Diagnostics Inc. System and method of measurement and calibration of analyte testing
GB2585227B (en) * 2019-07-04 2023-05-17 Mint Diagnostics Ltd Saliva testing
US11701036B2 (en) * 2019-07-10 2023-07-18 MX3 Diagnostics, Inc. Saliva test strip and method
WO2021016140A1 (en) 2019-07-19 2021-01-28 Micropoint Bioscience, Inc. Micro-assay cartridges
FR3100890B1 (fr) * 2019-09-17 2024-02-16 Innopsys Méthode et lecteur portable d’analyse d’échantillon de liquide biologique
JP7699138B2 (ja) 2020-01-30 2025-06-26 エムエックススリー・ダイアグノスティクス・インコーポレイテッド 生体液試料の評価
CN111307794A (zh) * 2020-03-30 2020-06-19 上海舒爽材料科技有限公司 嘴动式口腔检测机构及相应的智能口腔检测仪
CN115968445A (zh) 2020-04-08 2023-04-14 以色列农业和农村发展部农业研究组织(范卡尼中心) 确定人群中SARS-CoV-2的患病率的系统和方法
US12000823B2 (en) * 2020-07-11 2024-06-04 Matthew Hummer Simultaneous disease detection system method and devices
JP2022019626A (ja) * 2020-07-15 2022-01-27 エコセンス 被験者の肝臓の健康状態に関係するパラメータを決定するためのシステムおよび方法
JP2022032479A (ja) * 2020-08-12 2022-02-25 株式会社ファーストスクリーニング 電気化学センサユニット
CN112113955B (zh) * 2020-09-15 2022-03-18 四川行之智汇知识产权运营有限公司 血红蛋白检测卡
WO2022094707A1 (en) * 2020-11-04 2022-05-12 Pelican Diagnostics Inc. Portable devices and methods for detecting and identifying compounds in a fluid sample
US12390807B2 (en) * 2021-04-29 2025-08-19 Beijing Boe Technology Development Co., Ltd. Chip loading structure, analysis device, and analysis system
US11892425B2 (en) * 2021-05-18 2024-02-06 Matthew Hummer Device for reading, processing and transmitting test result data for pathogens or viruses in fluid test samples
WO2022245542A2 (en) * 2021-05-18 2022-11-24 Matthew Hummer Method and devices for detecting viruses and bacterial pathogens
WO2023288272A1 (en) * 2021-07-16 2023-01-19 Siemens Healthcare Diagnostics Inc. Detection of abnormal heat exchanger operating condition
US12455258B2 (en) * 2022-04-19 2025-10-28 Lg Electronics Inc. Biosensor chip and biosensor cartridges having the same
US20230408438A1 (en) * 2022-06-15 2023-12-21 Oregon State University Electrocatalytic polymer device for biological detection
WO2024016077A1 (en) * 2022-07-19 2024-01-25 Hylid Diagnostics Inc. Point-of-care blood analysis system
GB2631113A (en) * 2023-06-20 2024-12-25 Tachmed Holdings Ltd Sensor unit
EP4671772A2 (en) * 2024-03-14 2025-12-31 Leica Microsystems CMS GmbH FLUID DISTRIBUTOR FOR SUPPLYING FLUID TO A MICROFLUID SYSTEM AND FLUID CONTAINER

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060264783A1 (en) * 2005-05-09 2006-11-23 Holmes Elizabeth A Systems and methods for monitoring pharmacological parameters
US20070081920A1 (en) * 2005-10-12 2007-04-12 Murphy R S Semi-disposable optoelectronic rapid diagnostic test system
CN101098956A (zh) * 2002-12-26 2008-01-02 梅索磅秤技术有限公司 检定盒及其使用方法
US20080217246A1 (en) * 2007-03-09 2008-09-11 Dxtech, Llc. Electrochemical detection system
US20110005932A1 (en) * 2009-06-05 2011-01-13 Integenx Inc. Universal sample preparation system and use in an integrated analysis system
CN102713621A (zh) * 2009-11-23 2012-10-03 西维克公司 用于施行化验的方法和设备
WO2013014540A2 (en) * 2011-07-22 2013-01-31 Biosensia Patents Limited Reader device for luminescent immunoassays

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU758407B2 (en) * 1997-12-24 2003-03-20 Cepheid Integrated fluid manipulation cartridge
US6893552B1 (en) 1997-12-29 2005-05-17 Arrowhead Center, Inc. Microsensors for glucose and insulin monitoring
DE69902662T2 (de) 1998-06-01 2009-10-08 Roche Diagnostics Operations, Inc., Indianapolis Redox-reversibele bipyridyl-osmiumkomplex-konjugate
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US7419821B2 (en) * 2002-03-05 2008-09-02 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
US20030224371A1 (en) 2002-06-04 2003-12-04 Thomas Bradley S. Integrated cartridge for sample manipulation
AU2003297214A1 (en) * 2002-12-16 2004-07-22 Cytodiscovery, Inc. Microfluidic system with integrated permeable membrane
US7887750B2 (en) * 2004-05-05 2011-02-15 Bayer Healthcare Llc Analytical systems, devices, and cartridges therefor
US7776583B2 (en) 2004-06-03 2010-08-17 Meso Scale Technologies, Llc Methods and apparatuses for conducting assays
EP1888235A1 (en) 2005-06-06 2008-02-20 Decision Biomarkers Incorporated Assays based on liquid flow over arrays
JP2009518113A (ja) * 2005-12-09 2009-05-07 フレキシブル メディカル システムズ， エルエルシー 監視および送達のための可撓性装置および方法
GB0618966D0 (en) 2006-09-26 2006-11-08 Iti Scotland Ltd Cartridge system
WO2008044530A1 (en) * 2006-10-05 2008-04-17 Panasonic Corporation Multicomponent analysis sensor and method of measuring multiple components
EP2535704B1 (en) * 2007-09-24 2015-09-09 Bayer HealthCare LLC Multi-electrode test method
GB0820817D0 (en) * 2008-11-13 2008-12-24 Wireless Biodevices Ltd Electrode, electrochemical sensor and apparatus, and methods for operating the same
US9212995B2 (en) * 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
EP3109618B1 (en) 2009-12-07 2019-02-27 Meso Scale Technologies, LLC. Assay cartridge comprising a sample chamber
GB201014805D0 (en) * 2010-09-07 2010-10-20 Multi Sense Technologies Ltd Microfluidics based assay device
GB201102037D0 (en) * 2011-02-07 2011-03-23 Multi Sense Technologies Ltd Microfluidics based assay device
EP2737315B1 (en) 2011-07-25 2022-03-16 Proxim Diagnostics Corporation Cartridge for diagnostic testing
US9772310B2 (en) * 2011-07-28 2017-09-26 Kyocera Corporation Biosensor
US20140377789A1 (en) * 2012-02-10 2014-12-25 Alere Switzerland Gmbh Assay and method for determining insulin-resistance
US20150060272A1 (en) 2013-03-15 2015-03-05 Nanomix, Inc. Amperometric detection of limulus amebocyte lysate activation by endotoxin and/or 1-3-beta-d-glucan
US9458488B2 (en) 2013-03-15 2016-10-04 Nanomix, Inc. Point of care sensor systems

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101098956A (zh) * 2002-12-26 2008-01-02 梅索磅秤技术有限公司 检定盒及其使用方法
US20060264783A1 (en) * 2005-05-09 2006-11-23 Holmes Elizabeth A Systems and methods for monitoring pharmacological parameters
CN101535499A (zh) * 2005-05-09 2009-09-16 赛拉诺斯股份有限公司 点护理射流系统及其应用
US20070081920A1 (en) * 2005-10-12 2007-04-12 Murphy R S Semi-disposable optoelectronic rapid diagnostic test system
CN1948952A (zh) * 2005-10-12 2007-04-18 安捷伦科技有限公司 半可抛式光电快速诊断测试系统
US20080217246A1 (en) * 2007-03-09 2008-09-11 Dxtech, Llc. Electrochemical detection system
US20110005932A1 (en) * 2009-06-05 2011-01-13 Integenx Inc. Universal sample preparation system and use in an integrated analysis system
CN102713621A (zh) * 2009-11-23 2012-10-03 西维克公司 用于施行化验的方法和设备
WO2013014540A2 (en) * 2011-07-22 2013-01-31 Biosensia Patents Limited Reader device for luminescent immunoassays

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
樊春海;: "纳米生物传感器", 世界科学, no. 11 *

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