CN113679508A

CN113679508A - Implant for increasing aqueous humor outflow and production method of implant

Info

Publication number: CN113679508A
Application number: CN202110983554.8A
Authority: CN
Inventors: 叶聪
Original assignee: Eye Hospital of Wenzhou Medical University
Current assignee: Eye Hospital of Wenzhou Medical University
Priority date: 2021-08-25
Filing date: 2021-08-25
Publication date: 2021-11-23

Abstract

The invention discloses an implant for increasing aqueous humor outflow and a production method of the implant. The implant is designed into a tubular shape, and after the implant is implanted into an eye, the tube body has better expansion and supporting effects on the assembly in the eye, so that the flow guide channel is prevented from being blocked by the assembly in the eye, and the smoothness of the flow guide channel can be kept. And is more suitable for the use in the angle-closure glaucoma and more suitable for the condition of Chinese patients.

Description

Implant for increasing aqueous humor outflow and production method of implant

Technical Field

The invention relates to the technical field of ophthalmic medical instruments, in particular to an implant for increasing aqueous humor outflow and a production method of the implant.

Background

US patent No. US9351874B2 discloses a method and apparatus for delivering an ocular implant into an eye, where the implant is in the form of a long sheet with a circular arc, and the cross-section of the implant is circular arc, the outer side of the arc of the implant has a convex structure, and the inner side of the arc of the implant is provided with a flow-guiding hole.

However, the implant can only be matched with a special puncture mechanism, and after the puncture mechanism punctures the eye, the implant is sent into the eye, and in the use process, because the implant is in a sheet shape and is in an open form, the opening and supporting performance of the liquid guide channel in the eye is poor, and the implant is easily blocked by the tissues in the eye. The product is more suitable for the open-angle glaucoma, and the Chinese glaucoma is mainly closed-angle glaucoma accounting for about 90 percent, so that the product is rarely applied at home.

Disclosure of Invention

In view of the deficiencies of the prior art, the present invention provides an implant that increases aqueous humor outflow and is not easily occluded by intraocular assembly.

The invention provides the following technical scheme: the utility model provides an increase implant that aqueous humor flows, is including being circular-arc body, has seted up a plurality of first drainage holes on the lateral wall in the body outside, has seted up a plurality of second drainage holes on the inboard lateral wall of body, and the one end of body is provided with the puncture portion.

Preferably, a notch is arranged on the side wall of the inner side of one end of the tube body, which faces away from the puncture part.

Preferably, puncture portion and breach all are provided with two, and the symmetry sets up the both ends at the body.

Preferably, the length of the pipe body is 7-10mm, the diameter is 0.3-0.4 mm, and the radian is 80-100 degrees.

Preferably, the mouth part of the first drainage hole is in an elliptic curved surface shape, the center of the first drainage hole coincides with the outermost side line of the pipe body, the mouth part is in a concave shape towards the inner side of the pipe body, the mouth part of the first drainage hole is 1.1-1.4 mm long, the distance between the bottom and the inner side line is 0.06-0.1 mm, the interval between two adjacent first drainage holes is 0.3-0.4 mm, the second drainage hole is in a waist shape, the center of the second drainage hole coincides with the innermost side line of the pipe body and is arranged at the central position of the two first drainage holes, and the length of the second drainage hole is 1-1.2 mm.

The invention also provides a method for producing the implant, which comprises the steps of

The method comprises the following steps: extruding the alloy pipe blank into an alloy pipe with the diameter of 12mm, wherein the extrusion temperature is 600-700 ℃;

step two: the alloy pipe is processed by cold rolling for many times, the processing rate of each time is 15% -20%, and the alloy pipe is processed into the alloy pipe with the diameter of 0.4 mm;

step three: drawing the cold-rolled alloy pipe for multiple times to thin the pipe wall to reach the required pipe wall, wherein the drawing processing rate is not more than 30% each time;

step four: bending the stretched alloy pipe to enable the alloy pipe to be bent into a pipe shape;

step five: grinding puncture parts at two ends of the bent alloy pipe;

step six: and after the grinding is finished, laser cutting a first drainage hole, a second drainage hole and a notch on the alloy pipe.

The invention has the beneficial effects that: the implant is designed into a tubular shape, and after the implant is implanted into an eye, the tube body has better expansion and supporting effects on the assembly in the eye, so that the flow guide channel is prevented from being blocked by the assembly in the eye, and the smoothness of the flow guide channel can be kept. And is more suitable for the use in the angle-closure glaucoma and more suitable for the condition of Chinese patients.

Drawings

FIG. 1 is an overall block diagram of the present invention;

fig. 2 is a cross-sectional view of a tube.

Detailed Description

The invention will be further described in detail with reference to the following examples, which are given in the accompanying drawings.

Referring to fig. 1-2, the present invention provides a technical solution: the utility model provides an increase implant that aqueous humor flows out, is including being circular-arc body 1, has seted up a plurality of first drainage holes 11 on the lateral wall in the body 1 outside, has seted up a plurality of second drainage holes 12 on the lateral wall in body 1 inboard, and the one end of body 1 is provided with puncture portion 13.

The implant is designed into a tubular shape, after the implant is implanted into an eye, the tube body 1 has better expansion and supporting effects on the intraocular assembly, the flow guide channel is prevented from being blocked by the intraocular assembly, and the smoothness of the flow guide channel can be kept.

The side wall of the inner side of one end of the tube body 1, which is back to the puncture part 13, is provided with a notch 14, and the notch 14 is designed to be conveniently matched with a handle to be grabbed.

The puncture parts 13 and the notches 14 are arranged in two numbers and are symmetrically arranged at two ends of the tube body 1. Through the design of the two notches 14 and the puncture part 13, both ends of the implant can be punctured for drainage, and the use is more convenient.

The length of the pipe body 1 is 7-10mm, the diameter is 0.3-0.4 mm, and the radian is 80-100 degrees.

Through the design, the tube 1 is more suitable for puncture and drainage in eyes.

The mouth part 111 of the first drainage hole 11 is in an elliptic curved surface shape, the center of the first drainage hole 11 coincides with the outermost sideline of the tube body 1, the mouth part 111 is in a concave shape towards the inner side of the tube body 1, the mouth part 111 of the first drainage hole 11 is 1.1-1.4 mm long, the distance between the bottom and the inner sideline is 0.06-0.1 mm, the interval between two adjacent first drainage holes 11 is 0.3-0.4 mm, the second drainage hole 12 is in a waist shape, the center of the second drainage hole 12 coincides with the innermost sideline of the tube body 1 and is arranged at the center position of the two first drainage holes 11, and the length of the second drainage hole 12 is 1-1.2 mm.

Through the setting, the positions of arranging the first drainage holes 11 and the second drainage holes 12 are more uniform, so that the overall structural strength is more uniform, local deformation is avoided, the large drainage area is considered, and intraocular liquid can be discharged more quickly.

Through the design, the implant can be implanted into Schlemm's canal of eyeball through an internal path in a mode of less damage, increases the outflow of aqueous humor through a trabecular path, and is applied to open-angle glaucoma; the device can also be combined with classical trabeculectomy, and by implantation in an external way, aqueous humor is drained into a Schlemm's tube and is drained through a physiological way, so that the operation failure caused by scars is reduced, and the application to closed-angle glaucoma is realized.

A method of producing an implant comprising

step four: bending the stretched alloy pipe to enable the alloy pipe to be bent into the shape of a pipe body 1;

step five: grinding two ends of the bent alloy pipe to form a puncture part 13;

step six: after the grinding is finished, a first drainage hole 11, a second drainage hole 12 and a notch 14 are cut on the alloy pipe by laser.

Through multiple times of cold rolling and stretching, the method of gradually reducing the diameter and the pipe wall can reduce the deformation amount in a single processing process, and avoid the phenomenon that the structure is unstable due to cracks or local stress concentration on the surface caused by overlarge processing proportion. The processed implant has better mechanical property, smoother and smoother surface and more stable structure.

The above is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above-mentioned embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may occur to those skilled in the art without departing from the principle of the invention, and are considered to be within the scope of the invention.

Claims

1. An implant for increasing aqueous humor outflow, comprising: the drainage tube comprises a circular arc-shaped tube body (1), wherein a plurality of first drainage holes (11) are formed in the side wall of the outer side of the tube body (1), a plurality of second drainage holes (12) are formed in the side wall of the inner side of the tube body (1), and a puncture part (13) is arranged at one end of the tube body (1).

2. An implant for increasing aqueous humor outflow according to claim 1, wherein: a notch (14) is arranged on the side wall of the inner side of one end of the tube body (1) back to the puncture part (13).

3. An implant for increasing aqueous humor outflow according to claim 2, wherein: the puncture parts (13) and the notches (14) are arranged in two numbers and are symmetrically arranged at two ends of the tube body (1).

4. An implant for increasing aqueous humor outflow according to claim 3, wherein: the length of the pipe body (1) is 7-10mm, the diameter is 0.3-0.4 mm, and the radian is 80-100 degrees.

5. An implant for increasing aqueous humor outflow according to claim 4, wherein: the mouth part (111) of the first drainage hole (11) is in an elliptic curved surface shape, the center of the first drainage hole (11) coincides with the outermost side line of the pipe body (1), the mouth part (111) is in a concave shape towards the inner side of the pipe body (1), the mouth part (111) of the first drainage hole (11) is 1.1-1.4 mm long, the bottom is 0.06-0.1 mm away from the inner side line, two adjacent first drainage holes (11) are arranged at intervals of 0.3-0.4 mm, the second drainage hole (12) is in a waist shape, the center of the second drainage hole (12) coincides with the innermost side line of the pipe body (1) and is arranged at the central position of the two first drainage holes (11), and the second drainage hole (12) is 1-1.2 mm long.

6. A method of producing an implant, comprising: comprises that

step four: bending the stretched alloy pipe to enable the alloy pipe to be bent into the shape of a pipe body (1);

step five: grinding two ends of the bent alloy pipe to form a puncture part (13);

step six: and after the grinding is finished, laser cutting is carried out on the alloy tube to form a first drainage hole (11), a second drainage hole (12) and a notch (14).