CN113650924A

CN113650924A - Kit for auxiliary diagnosis of hepatocellular carcinoma

Info

Publication number: CN113650924A
Application number: CN202110831874.1A
Authority: CN
Inventors: 陈艳红; 牛国平
Original assignee: Xuzhou Central Hospital
Current assignee: Xuzhou Central Hospital
Priority date: 2021-07-22
Filing date: 2021-07-22
Publication date: 2021-11-16
Anticipated expiration: 2041-07-22
Also published as: CN113650924B

Abstract

The invention relates to the technical field of kits, in particular to a kit for auxiliary diagnosis of hepatocellular carcinoma, which comprises: the device comprises a device main body, wherein the device main body comprises a storage box, one end of the storage box is provided with four supporting soft pads; the storage box comprises a storage box body, a protective cover plate and a storage plate, wherein the protective cover plate is arranged on one surface of the storage box body; and the closing mechanism is arranged in the storage box. According to the invention, the partition plate, the gear, the transmission ring, the latch plate and the closing plate are arranged, so that medical personnel can drive the closing plate to rotate when pulling the storage plate, and the internal space of the storage box is in a closed-open-closed state, so that after the medical personnel pull out a single group of plasma samples, the rest of plasma samples can still be stored in the storage box for sealing, and thus, the subsequent plasma samples can be prevented from being rapidly warmed, and the possibility of infection is reduced.

Description

Kit for auxiliary diagnosis of hepatocellular carcinoma

Technical Field

The invention relates to the technical field of kits, in particular to a kit for auxiliary diagnosis of hepatocellular carcinoma.

Background

Hepatocellular carcinoma (HCC) is the major histological subtype of liver cancer, accounting for 90% of primary liver cancer, and is the third most common cause of cancer-related mortality worldwide. Inheritance, epigenetic change, chronic hepatitis B, hepatitis C virus infection, aflatoxin exposure, smoking, obesity, diabetes and the like are main risk factors of liver cancer. The poor prognosis of liver cancer is due to high recurrence rate and high metastasis rate. Transplantation is the most effective method for treating liver cancer, but the tumor recurrence rate and metastasis rate are high during transplantation. More than 70% of late stage patients are not suitable for transplantation, either because of tumor burden or poor liver function.

Hepatocellular carcinoma is one of the most common digestive tract tumors, with nearly 70 million people dying from hepatocellular carcinoma each year around the world in recent years, and with a tendency to rise year by year. Hepatocellular carcinoma is occured in a hidden state, symptoms appear later, most patients are developed to middle and late stages in clinical diagnosis, and due to the special anatomical position of the liver and important physiological functions of the liver, many patients lose the optimal surgical treatment period in the clinical diagnosis, in order to better understand the hepatocellular carcinoma, medical staff is often required to collect a large amount of blood of the patients for research and investigation, because the number of experimental samples is large, the detection of all samples is difficult to carry out at one time, all tissues and plasma samples need to be placed in a kit and stored at-80 ℃ for later use, but the traditional kit for storing the plasma samples in batches is simple in structure, after the kit is taken out from a cold storage, the medical staff generally detects the plasma samples in the kit in batches, so that the subsequent plasma samples are easy to rapidly heat up in the open kit, meanwhile, the probability of pollution is increased, so that a kit for auxiliary diagnosis of hepatocellular carcinoma needs to be designed.

Disclosure of Invention

The invention aims to provide a kit for assisting in diagnosing hepatocellular carcinoma, which solves the problems that in the background art, because the number of experimental samples is large, and the detection of all samples is difficult to carry out at one time, all tissues and plasma samples need to be placed in the kit and stored at-80 ℃ for later use, but the traditional kit for storing the plasma samples in batches has a simple structure, and medical staff generally detect the plasma samples in the kit in batches after taking the kit out of a cold storage, so that the temperature of the subsequent plasma samples is increased rapidly in the open kit, and the probability of pollution is increased.

In order to achieve the purpose, the invention provides the following technical scheme: a kit for aiding diagnosis of hepatocellular carcinoma comprising:

the device comprises a device main body, wherein the device main body comprises a storage box, one end of the storage box is provided with four supporting soft pads;

the storage box comprises a storage box body, a protective cover plate and a storage plate, wherein the protective cover plate is arranged on one surface of the storage box body;

closing mechanism, the inside of case is equipped with closing mechanism, and closing mechanism's quantity is two, closing mechanism includes the division board, and the quantity of division board is two, two all cup jointed the transmission seat through the pivot on the division board, the both sides of case inner surface all cup jointed the rotation seat through the pivot, two one side of rotating the seat has all cup jointed the gear, and one side of gear is connected on the transmission seat, two the inboard of transmission seat is connected with the closing plate, two the outside of gear all is provided with the drive ring, and the one side of drive ring is connected on the protective cover board, two all evenly install the pinion rack on the internal surface of drive ring, and the mounting means of pinion rack is the dislocation installation.

Preferably, the both ends of depositing the board all are equipped with a set of guide plate, and the quantity of every group guide plate is two, and is two sets of one side of guide plate all is connected on the internal surface of case, the sealing ring has been cup jointed in the outside of case, two the one end of driving ring all is equipped with the card and ends the mechanism.

Preferably, the both ends of depositing the board are all evenly installed and are cut apart the strip, fixed mounting has the sealing strip on the box inner surface of the case of closing plate one side, fixed mounting has the stopper on the box inner surface of the case of sealing strip one end, it installs and deposits the mechanism to deposit even embedding on the board.

Preferably, the storage plate both ends of cutting apart one side all fixed mounting have the assistance to prop the seat, two the assistance props the one end all fixed mounting of seat and has a set of mount pad, and the quantity of every group mount pad is three, and is two sets of all adjust through the pivot on the mount pad and have the assistance to prop the wheel, and the assistance props the outside of wheel and the internal surface of case and closely laminates.

Preferably, the two transmission rings are sleeved with limiting rings, limiting rods are inserted into the limiting rings, and one sides of the limiting rods are connected to the inner surface of the storage box.

Preferably, the card dun mechanism includes the card dun strip, the card dun strip is connected on the driving ring, the card dun strip is last evenly to have seted up the card and dun the groove, fixed mounting has the fixing base on the division board, one side fixed mounting of fixing base has a fixed cylinder, seted up the fixed slot in the fixed cylinder, the dead lever has been inserted in the fixed slot, and outside the one end of dead lever extended to the fixed slot, the dead lever one end fixed mounting in the fixed slot outside has the barrier ring, the inboard dead lever one end fixed mounting of fixed slot has the card dun head, buffer spring has been cup jointed in the outside of dead lever, and buffer spring's both ends are connected respectively on the inner wall of card dun head and fixed slot.

Preferably, the storage mechanism comprises a support plate, the support plate is embedded in the storage plate, an auxiliary plate is fixedly mounted at one end of the support plate, the auxiliary plate and the support plate are embedded with two storage sleeves, and label slots are fixedly mounted on the auxiliary plate on one side of each of the two storage sleeves.

Preferably, two all fixed mounting has the grip block in the backup pad of depositing the cover outside, two the centre gripping groove has all been seted up on the grip block, two all fixed mounting has a set of centre gripping spring on the inner wall in centre gripping groove, and the quantity of every centre gripping spring of group is two, two sets of fixed mounting all has the clamping head in the one end of centre gripping spring.

Compared with the prior art, the invention has the beneficial effects that:

1. through being provided with the division board, the gear, the driving ring, latch plate and closing plate, it takes place rotatoryly to drive the closing plate when utilizing medical personnel to stimulate the storage plate like this, thereby make the inner space of storage box present closed-open-closed state, thereby make medical personnel pull out the back with single group plasma sample, remaining plasma sample still can be preserved and sealed in the storage box inside, thereby avoid subsequent plasma sample to return the temperature fast, the possibility of infection has been reduced simultaneously, and this mechanism need not medical personnel and carries out too much operating procedure, make this device be convenient for medical personnel and use more.

2. Through being provided with the card and pause the mechanism, utilize the storage plate to remove the card that drives the activity and pause the head constantly and block the groove and carry out the block spacing and break away from the block like this to increased medical personnel and used the pause of this device and frustrated the sense, increased medical personnel's use and experienced, makeed medical personnel can confirm the upset state of closing plate better, avoid causing medical personnel to draw more or the condition of drawing less.

3. Through being provided with backup pad, accessory plate, deposit cover and label groove, utilize like this to deposit the cover and can fix the jar body of depositing the plasma sample, let the plasma sample more stable when depositing, medical personnel can place the label of experiment on the label groove simultaneously to be convenient for medical personnel to carry out record and discernment to subject's name and data.

Drawings

FIG. 1 is an exploded perspective view of the structure of the present invention;

FIG. 2 is a schematic bottom perspective view of the present invention;

FIG. 3 is a perspective view of the storage plate structure of the present invention;

FIG. 4 is a perspective view of a protective cover structure according to the present invention;

FIG. 5 is a perspective view of the guide plate according to the present invention;

FIG. 6 is a partial perspective view of the closure mechanism of the present invention;

FIG. 7 is a partial perspective view of the structure of the chucking mechanism of the present invention;

fig. 8 is a perspective view of the storage mechanism of the present invention.

In the figure: 1. a device main body; 110. a storage box; 111. a support cushion; 112. a protective cover plate; 113. a storage plate; 114. a guide plate; 115. a seal ring; 116. an auxiliary support seat; 117. a mounting seat; 118. auxiliary supporting wheels; 2. a closing mechanism; 210. a partition plate; 211. a drive ring; 212. a rotating seat; 213. a gear; 214. a transmission seat; 215. a toothed plate; 216. a closing plate; 217. a sealing strip; 218. a stop block; 219. a limiting ring; 220. a limiting rod; 221. cutting the strips; 3. a chucking mechanism; 310. a card pause bar; 311. a chucking groove; 312. a fixed seat; 313. a fixed cylinder; 314. fixing grooves; 315. fixing the rod; 316. a blocking ring; 317. clamping a head; 318. a buffer spring; 4. a storage mechanism; 410. a support plate; 411. an auxiliary plate; 412. storing the sleeve; 413. a label slot; 414. a clamping plate; 415. a clamping groove; 416. a clamping spring; 417. a clamping head.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-8, an embodiment of the present invention:

a kit for aiding diagnosis of hepatocellular carcinoma comprising:

the device comprises a device body 1, wherein the device body 1 comprises a storage box 110, one end of the storage box 110 is provided with four supporting soft pads 111;

a protective cover plate 112, wherein the protective cover plate 112 is arranged on one surface of the storage box 110, a storage plate 113 is fixedly arranged on one surface of the protective cover plate 112, and the storage plate 113 extends into the storage box 110;

the closing mechanism 2, the inside of the storage box 110 is provided with the closing mechanism 2, the number of the closing mechanism 2 is two, the closing mechanism 2 comprises two partition plates 210, the number of the partition plates 210 is two, transmission seats 214 are sleeved on the two partition plates 210 through rotating shafts, the two sides of the inner surface of the storage box 110 are sleeved with rotation seats 212 through rotating shafts, gears 213 are sleeved on one sides of the two rotation seats 212, one sides of the gears 213 are connected to the transmission seats 214, the inner sides of the two transmission seats 214 are connected with closing plates 216, the outer sides of the two gears 213 are provided with transmission rings 211, one sides of the transmission rings 211 are connected to the protective cover plate 112, the inner surfaces of the two transmission rings 211 are uniformly provided with clamping tooth plates 215, and the mounting mode of the clamping tooth plates 215 is staggered, so that when medical personnel pull the storage plate 113, the closing plates 216 are driven to rotate, and the inner space of the storage box 110 is in a closed-opened-closed state, thereby make medical personnel pull out the back with single group's plasma sample, remaining plasma sample still can be preserved at case 110 internal seal to avoid subsequent plasma sample to return the temperature fast, reduced the possibility of infecting simultaneously, and this mechanism need not medical personnel and carries out too much operating procedure, make this device be convenient for medical personnel more and use.

Furthermore, both ends of the storage plate 113 are provided with a set of guiding plates 114, and each set of guiding plates 114 is two, one side of each set of guiding plates 114 is connected to the inner surface of the storage box 110, the outer side of the storage box 110 is sleeved with a sealing ring 115, and one end of each of the two transmission rings 211 is provided with the locking mechanism 3, so that the guiding performance and stability of the movement of the storage plate 113 can be improved by using the guiding plates 114, and the sealing effect of the device during long-term storage can be improved by using the sealing rings 115.

Furthermore, the two ends of the storage plate 113 are uniformly provided with the cutting strips 221, the inner surface of the storage box 110 on one side of the sealing plate 216 is fixedly provided with the sealing strip 217, the inner surface of the storage box 110 on one end of the sealing strip 217 is fixedly provided with the stop block 218, and the storage plate 113 is uniformly embedded with the storage mechanism 4, so that the sealing strip 217 and the stop block 218 are used for stopping the overturning state of the two ends of the sealing plate 216, the sealing strip 217 and the cutting strips 221 can ensure the sealing effect of the sealing plate 216 and the inner wall of the storage box 110.

Further, the storage plate 113 both ends of cutting apart one side of strip 221 are all fixed mounting have the assistance to prop seat 116, two are assisted the one end of propping seat 116 and are all fixed mounting have a set of mount pad 117, and the quantity of every group mount pad 117 is three, all have the assistance to prop wheel 118 through the pivot regulation on two sets of mount pads 117, and the assistance props the outside of wheel 118 and the internal surface of case 110 and closely laminates, utilize the supporting capability who props wheel 118 and mount pad 117 like this, promoted the stable effect of storage plate 113.

Furthermore, the two driving rings 211 are sleeved with limiting rings 219, the limiting rods 220 are inserted into the two limiting rings 219, and one sides of the limiting rods 220 are connected to the inner surface of the storage box 110, so that the driving rings 211 can move more stably by using the limiting effect of the stop blocks 218 and the limiting rings 219.

Further, the clamping mechanism 3 includes a clamping bar 310, the clamping bar 310 is connected to the transmission ring 211, clamping grooves 311 are uniformly formed on the clamping bar 310, a fixing base 312 is fixedly installed on the separation plate 210, a fixing cylinder 313 is fixedly installed on one side of the fixing base 312, a fixing groove 314 is formed in the fixing cylinder 313, a fixing rod 315 is inserted into the fixing groove 314, one end of the fixing rod 315 extends out of the fixing groove 314, a blocking ring 316 is fixedly installed at one end of the fixing rod 315 outside the fixing groove 314, a clamping head 317 is fixedly installed at one end of the fixing rod 315 inside the fixing groove 314, a buffer spring 318 is sleeved outside the fixing rod 315, and two ends of the buffer spring 318 are respectively connected to the inner walls of the clamping head 317 and the fixing groove 314, so that the movable clamping head is driven by the movement of the storage plate 113 to be clamped and limited with and separated from the clamping grooves 311, thereby increasing the feeling of frustration of medical personnel using the device, the use experience of medical personnel is increased, so that the medical personnel can better determine the turning state of the closing plate 216, and the situation that the medical personnel pull more or less is avoided.

Further, deposit mechanism 4 including backup pad 410, backup pad 410 is installed on depositing board 113 in the embedding, the one end fixed mounting of backup pad 410 has accessory plate 411, the embedding is installed on accessory plate 411 and the backup pad 410 and is deposited cover 412, and the quantity of depositing cover 412 is two, fixed mounting has label groove 413 on the accessory plate 411 of two deposit cover 412 one sides, utilize like this to deposit cover 412 and can fix the jar body of depositing the plasma sample, it is more stable when depositing to let the plasma sample, medical personnel can place the label of experiment on label groove 413 simultaneously, thereby be convenient for medical personnel to take notes and discernment to subject's name and data.

Further, all fixed mounting has grip block 414 on the backup pad 410 of two outsides of depositing cover 412, all seted up centre gripping groove 415 on two grip blocks 414, all fixed mounting has a set of grip spring 416 on the inner wall of two centre gripping grooves 415, and the quantity of every group grip spring 416 is two, and the one end of two sets of grip spring 416 is fixed all fixed mounting has clamping head 417, utilizes the clamping effect of grip spring 416 and clamping head 417 to improve the stability that plasma placed on depositing the board 113 like this.

The working principle is as follows: when using this device when medical personnel use this device, at first pull protective cover plate 112 and drive and deposit board 113 and remove, thereby make driving ring 211 move outward, thereby drive the pinion rack 215 striking gear 213 with it intermeshing, thereby make gear 213 drive driving seat 214 and closing plate 216 take place rotatoryly, thereby make closing plate 216 upset, let closing plate 216 can not block backup pad 410 and accessory plate 411 promptly, let backup pad 410 and accessory plate 411 shift out the back, pinion rack 215 breaks away from the spacing effect to gear 213, thereby let closing plate 216 keep the stillness of certain time, later because the continuation of driving ring 211 removes, thereby make another pinion rack 215 that misplaces drive gear 213 and closing plate 216 counter-rotation, thereby make closing plate 216 reset.

Meanwhile, when the driving ring 211 moves, the limit ring 219 moves on the limit rod 220, the auxiliary support wheel 118 slides inside the storage box 110, the clamping head 317 is inserted into the clamping groove 311 each time the closing plate 216 is reset, and after the driving ring 211 continues to move, the clamping strip 310 is driven to strike the clamping head 317, so that the buffer spring 318 contracts, and the clamping head 317 and one of the clamping grooves 311 are relieved from limiting.

Put into storage sleeve 412 in proper order with the plasma sample when medical personnel, can extrude centre gripping head 417 and centre gripping spring 416 after the cover 412 is deposited in the entering of the plasma jar body to let centre gripping spring 416 shrink, and make it receive centre gripping spring 416's pressure and fixed, insert corresponding label in label groove 413 at last, and will deposit board 113 and reset and can accomplish and deposit the process, take out the process with the same reason.

It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. A kit for aiding diagnosis of hepatocellular carcinoma, comprising:

the device comprises a device main body (1), wherein the device main body (1) comprises a storage box (110), one end of the storage box (110) is provided with a supporting soft pad (111), and the number of the supporting soft pads (111) is four;

the storage box comprises a protective cover plate (112), wherein the protective cover plate (112) is arranged on one surface of the storage box (110), a storage plate (113) is fixedly installed on one surface of the protective cover plate (112), and the storage plate (113) extends into the storage box (110);

closing mechanism (2), the inside of case (110) is equipped with closing mechanism (2), and the quantity of closing mechanism (2) is two, closing mechanism (2) is including division board (210), and the quantity of division board (210) is two, two transmission seat (214) have all been cup jointed through the pivot on division board (210), the both sides of case (110) internal surface have all cup jointed through the pivot and have rotated seat (212), two gear (213) have all been cup jointed to one side of rotating seat (212), and one side of gear (213) is connected on transmission seat (214), two the inboard of transmission seat (214) is connected with closing plate (216), two the outside of gear (213) all is provided with transmission ring (211), and the one side of transmission ring (211) is connected on protective cover board (112), two the pinion rack (215) all evenly installed on the internal surface of transmission ring (211), and the latch plate (215) is installed in a staggered mode.

2. The kit for assisting in diagnosing hepatocellular carcinoma in accordance with claim 1, wherein: the both ends of depositing board (113) all are equipped with a set of guide plate (114), and the quantity of every group guide plate (114) is two, two sets of one side of guide plate (114) all is connected on the internal surface of case (110), sealing ring (115) have been cup jointed in the outside of case (110), two the one end of driving ring (211) all is equipped with card and stops mechanism (3).

3. The kit for assisting in diagnosing hepatocellular carcinoma in accordance with claim 1, wherein: both ends of depositing board (113) all evenly install and cut apart strip (221), fixed mounting has sealing strip (217) on the case (110) internal surface of closing plate (216) one side, fixed mounting has a stopper (218) on the case (110) internal surface of sealing strip (217) one end, it installs storage mechanism (4) to go up even embedding in depositing board (113).

4. The kit for assisting in diagnosing hepatocellular carcinoma in accordance with claim 3, wherein: the storage plate (113) both ends of cutting apart strip (221) one side are all fixed mounting have to assist and prop seat (116), two the one end of assisting and propping seat (116) is all fixed mounting have a set of mount pad (117), and the quantity of every group mount pad (117) is three, and is two sets of all adjust through the pivot on mount pad (117) and assist and prop wheel (118), and assist and prop the outside of wheel (118) and the interior surface of case (110) and closely laminate.

5. The kit for assisting in diagnosing hepatocellular carcinoma in accordance with claim 1, wherein: the two driving rings (211) are sleeved with limiting rings (219), limiting rods (220) are inserted into the limiting rings (219), and one sides of the limiting rods (220) are connected to the inner surface of the storage box (110).

6. The kit for assisting in diagnosing hepatocellular carcinoma in accordance with claim 2, wherein: the clamping mechanism (3) comprises a clamping bar (310), the clamping bar (310) is connected to the transmission ring (211), the clamping strips (310) are uniformly provided with clamping grooves (311), the partition plate (210) is fixedly provided with a fixed seat (312), a fixed cylinder (313) is fixedly arranged on one side of the fixed seat (312), a fixed groove (314) is arranged in the fixed cylinder (313), a fixed rod (315) is inserted into the fixed groove (314), one end of the fixing rod (315) extends out of the fixing groove (314), one end of the fixing rod (315) outside the fixing groove (314) is fixedly provided with a blocking ring (316), one end of a fixed rod (315) at the inner side of the fixed groove (314) is fixedly provided with a clamping head (317), the outer side of the fixed rod (315) is sleeved with a buffer spring (318), and both ends of the buffer spring (318) are respectively connected to the inner walls of the chucking head (317) and the fixing groove (314).

7. The kit for assisting in diagnosing hepatocellular carcinoma in accordance with claim 3, wherein: the storage mechanism (4) comprises a support plate (410), the support plate (410) is embedded in the storage plate (113), an auxiliary plate (411) is fixedly installed at one end of the support plate (410), storage sleeves (412) are embedded in the auxiliary plate (411) and the support plate (410), the number of the storage sleeves (412) is two, and label grooves (413) are fixedly installed on the auxiliary plate (411) on one side of the two storage sleeves (412).

8. The kit for assisting in diagnosing hepatocellular carcinoma in accordance with claim 7, wherein: two all fixed mounting has grip block (414), two on depositing the backup pad (410) in cover (412) outside all fixed mounting have grip block (415) on grip block (414), two all fixed mounting has a set of grip spring (416) on the inner wall of grip block (415), and the quantity of every group grip spring (416) is two, two sets of the fixed all fixed mounting of one end of grip spring (416) has holding head (417).