CN113598708A - Household device capable of detecting and treating early cancer and using method thereof - Google Patents

Household device capable of detecting and treating early cancer and using method thereof Download PDF

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Publication number
CN113598708A
CN113598708A CN202110719178.1A CN202110719178A CN113598708A CN 113598708 A CN113598708 A CN 113598708A CN 202110719178 A CN202110719178 A CN 202110719178A CN 113598708 A CN113598708 A CN 113598708A
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infrared light
controller
module
detector
light source
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Inventor
张馨予
王国华
孙祥琳
叶莉莎
周佳敏
吴昊
杨欢
姜正林
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Nantong University
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Nantong University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0036Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room including treatment, e.g., using an implantable medical device, ablating, ventilating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0625Warming the body, e.g. hyperthermia treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0626Monitoring, verifying, controlling systems and methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The invention discloses a household device capable of detecting and treating early cancers and a using method thereof, wherein the household device comprises a control main board, a probe board and an upper computer, wherein the probe board comprises a plurality of infrared light sources, a detector and a heating element, and the heating element is arranged on the outer ring of each infrared light source; the control main board comprises a controller, an infrared light source driving module, an analog-to-digital conversion module and a wireless module, the controller is connected with the infrared light source through the infrared light source driving module, the controller is connected with the detector through the analog-to-digital conversion module, the controller is connected with the heating element, and the controller is in communication connection with an upper computer through the wireless module; the household equipment of the invention utilizes the infrared detector to position the position of the canceration and utilizes the heating element to carry out auxiliary treatment, and the equipment has convenient use, low price and safety and is suitable for household use.

Description

Household device capable of detecting and treating early cancer and using method thereof
Technical Field
The invention belongs to the technical field of clinical medical detection, and particularly relates to household equipment capable of detecting and treating early cancer and a using method thereof.
Background
Cancer is a malignant stubborn disease and seriously threatens the health and life of people. Therefore, early diagnosis and intervention are very important steps, and the cure rate and the long-term survival rate of patients can be greatly improved. However, in the present stage, the detection and treatment methods of cancer are relatively complex and expensive, so that early screening and diagnosis and treatment of large-scale population cannot be realized.
The near-infrared light detection technology is a technology for researching tissue spectral characteristics and analyzing and deducing a lesion part by utilizing the specificity of hemoglobin in tissues on near-infrared light absorption and scattering. Compared with the traditional tumor detection imaging means in the current medical treatment, for example: the X-ray imaging technology, the nuclear magnetic resonance imaging technology, the ultrasonic imaging technology and the like have the important advantages of small and precise instruments, low production and application cost and the like. Meanwhile, researches show that the conventional thermotherapy can improve the sensitivity of tumor tissues, inhibit the respiration of tumor cells, induce the apoptosis of the tumor cells and change the immunogenicity of tumors at the local temperature of 45 ℃, thereby increasing the immune function of organisms. It is reported that tumor thermotherapy can improve the treatment effect of radiotherapy and chemotherapy by increasing the sensitivity of radiotherapy or chemotherapy, and has significant clinical value. The heat treatment can also increase the temperature of the pain part and improve the blood circulation through heat stimulation, thereby improving the nutrition metabolism and promoting the absorption of blood stasis. The traditional heat treatment methods are as follows: microwave thermotherapy, ultrasonic thermotherapy, radio frequency thermotherapy, etc. all have the shortcomings of large equipment volume, high cost, complex operation, inaccurate positioning, etc. Although the recent research combines the nanometer technology and the near infrared technology as a new technical means for tumor thermotherapy, the nanometer material is difficult to metabolize in human body, and the safety can not be guaranteed.
Disclosure of Invention
The invention aims to provide a household device capable of detecting and treating early cancer and a using method thereof.
In order to achieve the above purpose, the invention adopts a technical scheme as follows:
a household device capable of detecting and treating early cancers comprises a control main board, a probe board and an upper computer, wherein the probe board comprises a plurality of infrared light sources, a detector and a heating element, and the heating element is arranged on the outer ring of each infrared light source;
the control mainboard comprises a controller, an infrared light source driving module, an analog-to-digital conversion module and a wireless module, the controller is connected with the infrared light source by the infrared light source driving module, the controller is connected with the detector by the analog-to-digital conversion module, the controller is connected with the heating element, and the controller is in communication connection with the upper computer through the wireless module.
Further, every three detectors and one infrared light source form a right triangle, and the distances between the adjacent detectors are equal.
Furthermore, a filtering and amplifying module is connected between the analog-to-digital conversion module and the detector.
Further, the analog-to-digital conversion module adopts an ADS1158 module, the detector adopts an OPT101 detector, the wireless module adopts a ZigBee module, the infrared light source adopts an L735 infrared light source, the infrared light source driving module adopts a TLC5945 module, and the heating element adopts a thermistor.
The invention also provides a method for using the household equipment for detecting and treating early cancer, which comprises the following steps:
s1: placing a probe plate on a part to be detected of a body, and emitting infrared rays with 3 different wavelengths by using an infrared light source;
s2: the detector receives the reflected infrared light ray signals, the reflected infrared light ray signals are subjected to analog-to-digital conversion to form infrared light ray digital signals, and the infrared light ray digital signals are sent to the controller, and the controller sends the infrared light ray digital signals to the upper computer by using the wireless module;
s3: the upper computer processes the infrared light digital signals by adopting a gridddata algorithm to form a two-dimensional image, and the abnormal part in the two-dimensional image is marked with corresponding detector position coding information;
s4: and sending a heating element command to be heated to the controller by using the upper computer, wherein the position coding information of the heating element can be obtained by the position coding information of the detector.
Compared with the prior art, the technical scheme of the invention has the following advantages:
according to the household equipment, the canceration position is positioned by using the infrared light detector, the infrared light sources and the heating elements are in one-to-one correspondence, and people can independently select the heating position according to the abnormal part in the two-dimensional image obtained from the upper computer; in addition, every three detectors and one infrared light source form a right-angled triangle, the distances between adjacent detectors are equal, and the positions of the detectors are reasonably and uniformly arranged, so that a two-dimensional image can be accurately obtained in an upper computer; the equipment is small in size, convenient to take and store, suitable for household use, and the thermistor is quicker, more convenient and safer than other thermal therapy methods, so that the equipment has the advantages of convenience in use, low price, safety and easiness in popularization.
Drawings
FIG. 1 is a block diagram of a control system for a home appliance that can detect and treat early stage cancer in one embodiment of the present invention;
FIGS. 2 and 3 are front and side views, respectively, of a probe card in accordance with an embodiment of the present invention;
fig. 4 is a circuit connection diagram of a controller and an infrared light source driving module according to an embodiment of the invention;
FIG. 5 is a schematic circuit diagram of a detector in accordance with an embodiment of the present invention;
FIG. 6 is a flow chart of a method for using a home appliance to detect and treat early stage cancer in accordance with an embodiment of the present invention;
FIG. 7 is a flowchart of the griddata algorithm of MATLAB4, according to an embodiment of the present invention;
reference numerals: the device comprises a control main board 1, a controller 11, an infrared light source driving module 12, an analog-to-digital conversion module 13, a wireless module 14, a filtering amplification module 15, a probe board 2, an infrared light source 21, a detector 22, a heating element 23 and an upper computer 3.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1, a household device capable of detecting and treating early cancer comprises a control main board 1, a probe board 2 and an upper computer 3, wherein the probe board 2 comprises a plurality of infrared light sources 21, a detector 22 and a heating element 23, the heating element 23 is arranged on the outer circle of the infrared light sources 21, and the probe board 2 is placed on a detection part of a user body;
control mainboard 1 contains controller 11, infrared light source drive module 12, analog-to-digital conversion module 13 and wireless module 14, controller 11 utilizes infrared light source drive module 12 and infrared light source 21 to connect, controller 11 utilizes analog-to-digital conversion module 13 and detector 22 to connect, still connect filtering amplification module 15 between analog-to-digital conversion module 13 and the detector 22 controller 11 and heating element 23 connect, controller 11 passes through wireless module 14 and host computer 3 communication connection.
In this embodiment, the infrared light source 21 is an LED light source, the LED light source includes an LED light source driving chip and a light emitting diode source group, and the light emitting diode source group includes three common anode diodes with wavelengths of 735nm, 805nm, and 850nm, respectively; the infrared light source 21 adopts an L735 infrared light source, the infrared light source driving module 12 adopts a TLC5945 module, and the infrared light source driving module 12 is adopted to ensure that the near-infrared light intensity emitted by each light source is the same; the filtering and amplifying module 15 consists of a passive low-pass filter built by a resistor of 5.1k omega and a capacitor of 330NF and a homodromous proportional operational amplifier chip TLV 4333; the analog-to-digital conversion module 13 adopts an ADS1158 module; the detector 22 adopts an OPT101 detector, and the structure of the OPT101 detector is shown in FIG. 5; the wireless module 14 adopts a ZigBee module, the ZigBee module consists of a CC2530 chip, a crystal oscillator circuit and an antenna circuit, and a P1.7 pin of the ZigBee module is connected with the controller 11 and the A/D converter to realize a wireless communication function; the heating element 23 adopts a thermistor with the model number of PT 200; the controller 11 adopts an STM32F103 integrated chip, the controller 11 controls the infrared light source driving module 12 by using an SPI sheet, and the specific connection mode can be shown in FIG. 4; the controller 11 controls the analog-to-digital conversion module 13 by using the SPI, and sequentially transmits the digital signals after the analog-to-digital conversion to the controller 11.
In a specific embodiment, the control main board 1 and the probe board 2 may be connected by two rows of pins, one row of pins is responsible for transmitting the voltage signal fed back by the photodetector 22, and the other row of interpolation is responsible for the control signal and the feedback signal fed back by the controller 11 on the main control board to each chip and module on the probe board 2. ADS1158 is a sampling analog-digital converter, and 16 paths of single-ended 5V input are selected; the ADS1158 chip performs A/D conversion, each ADC has access to analog signals of 14 channels, the ADS1158 chip performs data communication with the controller 11 through the SPI, and the converted 16-bit digital signals of the 16 channels are sequentially transmitted to the controller 11 unit according to a signal format. The STM32F103VET6 chip has 512K bytes of flash program memory and has enough program writing space. The off-chip crystal oscillator provides 8M oscillation frequency; settings include ADC, SPI, 2IC and serial USART. The chip has 100 ports, and 80 ports can be used as general I/O.
The working principle of the equipment of the invention is as follows: the controller 11 utilizes the infrared light source driving module 12 to control the infrared light source 21 to emit infrared light with 3 different wavelengths, the detector 22 receives reflected infrared light signals, the infrared light signals are filtered and amplified by the filtering and amplifying module 15 and converted by analog-digital signals of the analog-digital conversion module 13 to form infrared light digital signals, the infrared light digital signals are transmitted to the controller 11, the controller 11 utilizes the wireless module 14 to transmit the infrared light digital signals to the upper computer 3, the upper computer 3 is internally provided with an APP, the APP is internally provided with an interpolation method (griddata) of MATLAB irregular point image interpolation function, imaging tasks such as reconstruction of a two-dimensional image and the like are realized, because the reflected infrared light signals after the infrared light passes through human tissues are closely related to absorption and scattering of near infrared light by hemoglobin in the human tissues, and abnormal parts in the two-dimensional image and the two-dimensional image can be obtained by combining related algorithms through infrared technology, in order to perform thermal therapy on the abnormal part, the position of the detector 22 needs to be coded, and the detector 22 and the infrared light source 21 have a corresponding relation, so that the heating element 23 which needs to be heated can be positioned, people can independently select the heating element to heat, the heating time and the heating temperature can be automatically set, the general temperature can be set to be 45 ℃, and the auxiliary heating time is 30min, so that the thermal therapy on the diseased part can be performed.
The griddata algorithm specific flow of MATLAB4 can be found in fig. 7.
In a specific embodiment, the household appliance is a machine with the length of 70cm, the width of 50cm and the thickness of 5cm, two sides of the machine are provided with felts, and the machine can be rolled, and the probe board 2 and the control panel are positioned in the appliance. In some embodiments, to better collect the reflected infrared light, every third detector 22 and every infrared light source 21 form a right triangle and the distances between adjacent detectors 22 are equal, as shown in fig. 2 and 3. The probe plate 2 comprises 350 infrared light sources 21, the distance between each infrared light source 21 and the adjacent three detectors 22 is 20mm, 14mm and 20mm, the infrared light sources 21 at the periphery of the probe plate 2 are provided with 3 or 5 detectors 22, the middle infrared light source 21 is provided with 8 detectors 22, for example, the infrared light source 1 is provided with the detectors 1, 2 and 3, the infrared light source 2 is provided with the detectors 1, 4, 5, 6 and 7, and the infrared light source 5 is provided with the detectors 1, 2, 3, 4, 14, 20, 15 and 5 detectors 22.
The present invention also provides a method for using a home appliance for detecting and treating early cancer, as shown in fig. 6, comprising the steps of:
s1: placing the probe plate 2 on a part to be detected of a body, and emitting 3 infrared rays with different wavelengths by using an infrared light source 21;
s2: the detector 22 receives the reflected infrared light signal, and converts the reflected infrared light signal into an infrared light digital signal through analog-to-digital conversion, and sends the infrared light digital signal to the controller 11, and the controller 11 sends the infrared light digital signal to the upper computer 3 by using the wireless module 14;
s3: the upper computer 3 processes the infrared light digital signals by adopting a griddata algorithm to form a two-dimensional image, and the abnormal part in the two-dimensional image is marked with corresponding position coding information of the detector 22; the normal corresponding abnormal part can be highlighted by bright area
S4: and sending a heating element 23 command to be heated to the controller 11 by using the upper computer 3, wherein the position coding information of the heating element 23 can be obtained by the position coding information of the detector 22.
The heating temperature and the heating time can be set automatically.
The above examples are merely illustrative of several embodiments of the present invention, which are described in more detail and detail but are not to be construed as limiting the scope of the present invention. Various modifications and alterations to this invention will become apparent to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (9)

1. The household equipment capable of detecting and treating early cancers is characterized by comprising a control main board, a probe board and an upper computer, wherein the probe board comprises a plurality of infrared light sources, a detector and a heating element, and the heating element is arranged on the outer ring of each infrared light source;
the control mainboard comprises a controller, an infrared light source driving module, an analog-to-digital conversion module and a wireless module, the controller is connected with the infrared light source by the infrared light source driving module, the controller is connected with the detector by the analog-to-digital conversion module, the controller is connected with the heating element, and the controller is in communication connection with the upper computer through the wireless module.
2. The home appliance for detecting and treating early cancer according to claim 1, wherein every three detectors and one infrared light source form a right triangle and the distances between adjacent detectors are equal.
3. The domestic apparatus for detecting and treating early cancer according to claim 1, wherein a filtering and amplifying module is further connected between said analog-to-digital conversion module and the detector.
4. The home appliance for detecting and treating early cancer according to claim 3, wherein the analog-to-digital conversion module employs ADS1158 module.
5. The home-use device for detecting and treating early cancer according to claim 4, wherein the detector is an OPT101 detector.
6. The home device for detecting and treating early cancer according to claim 5, wherein the wireless module is a ZigBee module.
7. The domestic apparatus for detecting and treating early cancer according to claim 6 wherein said infrared source is L735 infrared source and said infrared source driving module is TLC5945 module.
8. The domestic device for detecting and treating early cancer according to claim 7, wherein said heating element is a thermistor.
9. A method of using a home appliance for the detection and treatment of early stage cancer according to any one of claims 1-8, comprising the steps of:
s1: placing a probe plate on a part to be detected of a body, and emitting infrared rays with 3 different wavelengths by using an infrared light source;
s2: the detector receives the reflected infrared light ray signals, the reflected infrared light ray signals are subjected to analog-to-digital conversion to form infrared light ray digital signals, and the infrared light ray digital signals are sent to the controller, and the controller sends the infrared light ray digital signals to the upper computer by using the wireless module;
s3: the upper computer processes the infrared light digital signals by adopting a gridddata algorithm to form a two-dimensional image, and the abnormal part in the two-dimensional image is marked with corresponding detector position coding information;
s4: and sending a heating element command to be heated to the controller by using the upper computer, wherein the position coding information of the heating element can be obtained by the position coding information of the detector.
CN202110719178.1A 2021-06-28 2021-06-28 Household device capable of detecting and treating early cancer and using method thereof Pending CN113598708A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203915198U (en) * 2014-05-06 2014-11-05 南阳医学高等专科学校第一附属医院 A kind of mode of wireless transmission tumor thermotherapy device
CN204092868U (en) * 2014-07-18 2015-01-14 李超 Tumour radiotherapy bed
CN104352221A (en) * 2014-11-10 2015-02-18 电子科技大学 Portable type optical noninvasive breast self-inspection instrument
CN106618501A (en) * 2016-12-29 2017-05-10 哈尔滨工业大学 Tumor imaging system based on near-infrared spectrum blood oxygen concentration measurement and experiment detection method of system
CN107261337A (en) * 2017-07-19 2017-10-20 吉彦 Cancer treating instrument
CN107432989A (en) * 2017-08-31 2017-12-05 南京医科大学 The system and method for prevention and adjuvant treatment of breast cancer based on far infrared
CN108742827A (en) * 2018-06-06 2018-11-06 俞雪利 Novel tumor heat treatment unit and its control method

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203915198U (en) * 2014-05-06 2014-11-05 南阳医学高等专科学校第一附属医院 A kind of mode of wireless transmission tumor thermotherapy device
CN204092868U (en) * 2014-07-18 2015-01-14 李超 Tumour radiotherapy bed
CN104352221A (en) * 2014-11-10 2015-02-18 电子科技大学 Portable type optical noninvasive breast self-inspection instrument
CN106618501A (en) * 2016-12-29 2017-05-10 哈尔滨工业大学 Tumor imaging system based on near-infrared spectrum blood oxygen concentration measurement and experiment detection method of system
CN107261337A (en) * 2017-07-19 2017-10-20 吉彦 Cancer treating instrument
CN107432989A (en) * 2017-08-31 2017-12-05 南京医科大学 The system and method for prevention and adjuvant treatment of breast cancer based on far infrared
CN108742827A (en) * 2018-06-06 2018-11-06 俞雪利 Novel tumor heat treatment unit and its control method

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Application publication date: 20211105