CN113577166B - Medicinal oil and preparation method thereof - Google Patents
Medicinal oil and preparation method thereof Download PDFInfo
- Publication number
- CN113577166B CN113577166B CN202110990842.6A CN202110990842A CN113577166B CN 113577166 B CN113577166 B CN 113577166B CN 202110990842 A CN202110990842 A CN 202110990842A CN 113577166 B CN113577166 B CN 113577166B
- Authority
- CN
- China
- Prior art keywords
- parts
- oil
- medicinal oil
- fructus
- oxytropis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides medicinal oil and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The medicinal oil comprises the following raw materials: scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, fructus Oxytropis, fructus Terminaliae Billericae and oleum Camelliae. The method comprises the following steps: crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, semen Oxytropis and fructus Chebulae, soaking in water, and taking out; adding ethanol into the soaked raw materials, heating, refluxing and extracting to obtain residues; adding tea oil into the residue, decocting, and filtering to obtain medicinal oil product. The medicines supplement each other and play a role in diminishing inflammation, relieving itching, cooling blood, removing toxicity, dissipating blood stasis, relieving swelling, activating blood and relieving pain.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to medicinal oil and a preparation method thereof.
Background
Traumatic injury seems to be a daily meal for some people in daily life, and generally refers to soft tissue injury caused by falling, hitting, bumping or knocking and the like, and is mainly manifested by swelling and pain. If the traumatic injury is treated improperly, old injuries can be formed, and permanent pain can be brought to the body. The traumatic injury is characterized in that after body tissues are injured by external force, an inflammatory reaction is shown, a large amount of liquid seeps from blood vessels to a sprain part, so that local swelling occurs, and then nerves are pressed, and pain is caused. This reaction typically peaks within 24 hours.
The traditional Chinese medicine for treating traumatic injuries has a history of thousands of years, and the ancient name of traumatic injuries is a general theory of injuries, and is mostly caused by the action of external force or the exertion of excessive force under the condition of incorrect posture. In traditional Chinese medicine, injuries of bones and muscles, swelling and pain due to blood stasis, disharmony between qi and blood, meridian obstruction and organ damage caused by external force acting on human body are collectively called traumatic injury. Traumatic injuries mainly caused by acute and chronic soft tissue injuries are common diseases and high morbidity in modern life, and the injuries mostly have the conditions of pain, swelling, bleeding, fracture, dislocation and the like. Soft tissue injury, which is called as "soft tissue injury" in traditional Chinese medicine. The soft tissues such as tendons and tendons are the important parts of joints, and the source of miscellaneous diseases Xixi candle says that the tendon is also the muscle, so that the joints are tied up, the flesh is caught and the skin is tensed, which is the key point of the whole body and is beneficial to the whole body. In other words: the total convergence of tendons is located in the knee. "Lingshu" cloud: all tendons belong to the section. So that the movement of flexion and extension is all the tendons. When traumatic injuries occur, the most injuries occur when the tendons are flushed first. Clinically, sprain or contusion can cause muscle and tendon injury, local swelling and pain, bluish purple and unsmooth flexion and extension of joints. Most of the soft tissue injuries are qi and blood stasis, meridian obstruction and local swelling, obvious pain, tissue bleeding or edema and the like caused by injury, and massive blood stasis. Su Wen, the grand treatise on the truth: "all pains, itching and sores all belong to the heart", and "the book Sheng Ji Zong Men" says that if the channels and collaterals are disturbed by injury and the blood circulation is not smooth and the stasis is not scattered, the swelling is pain, and it is advisable to remove the stasis and to circulate the qi and blood, so it is also possible to recover the safety.
At present, the treatment of traumatic injury is implemented by adopting steel plate reduction fixation treatment in western medicine; the traditional Chinese medicine is treated by various medicines and has certain effects. The traditional Chinese medicine oil is often used as an external medicament, is suitable for relieving pain of various factors, can also be selected from traditional Chinese medicine therapies such as massage, acupuncture and the like, is inconvenient if the traditional Chinese medicine therapies are long in time and high in price, and is matched with the traditional Chinese medicine oil for treating most people, but the traditional Chinese medicine oil in the market has single component proportion, cannot achieve good ideal effect, and cannot help treatment.
Disclosure of Invention
The invention aims to provide medicinal oil which has a good effect of treating traumatic injury.
The invention also aims to provide a preparation method of the medicinal oil, so as to prepare the medicinal oil with good effect of treating traumatic injury.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
On one hand, the embodiment of the application provides medicinal oil which comprises the following raw materials in parts by weight: 20-40 parts of scutellaria baicalensis, 20-40 parts of gardenia, 20-40 parts of phellodendron, 10-30 parts of coptis chinensis, 20-40 parts of mint, 5-25 parts of oxytropis, 5-25 parts of fructus terminaliae billericae and 450-560 parts of tea oil.
On the other hand, the embodiment of the application provides a preparation method of medicinal oil, which comprises the following steps: crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, semen Oxytropis and fructus Chebulae, soaking in water, and taking out; adding ethanol into the soaked raw materials, heating and refluxing for extraction to obtain residues; adding tea oil into the residue, heating, decocting, and filtering to obtain medicinal oil product.
Scutellaria baicalensis: bitter taste and cold nature. It enters lung, gallbladder, spleen, large intestine and small intestine meridians. Has effects in clearing away heat, eliminating dampness, purging pathogenic fire, removing toxic materials, stopping bleeding, and preventing miscarriage. Can be used for treating damp warmth, summer warmth, chest distress, emesis, dampness-heat distention and fullness, dysentery, jaundice, cough due to lung heat, hyperpyrexia, polydipsia, blood heat, hematemesis, carbuncle, swelling, sore, and threatened abortion. The book materia Medica is as follows: the withered patient clears the upper-jiao fire, eliminates phlegm, promotes qi, relieves asthma, relieves blood loss, reduces alternating cold and heat, wind-heat damp and heat, headache, relieves pestilence, clears throat, treats flaccidity of lung and carbuncle on the lung, carbuncle on the back of the breast and particularly dispels heat on the skin surface, so the medicament is used for treating macula, fistula, pyocutaneous disease and red eyes; the excessive cold-heat in the lower energizer can remove dysentery, heat accumulation in the bladder, stranguria with the five urinary organs, constipation, hematochezia and blood leakage. "scientific folk medicine and grass: the wound is washed outside and has antiseptic effect. "
Gardenia: bitter taste and cold nature. It enters heart, lung and triple energizer meridians. Has the effects of purging fire, relieving restlessness, clearing heat, promoting urination, cooling blood and removing toxic substances. It is indicated for feverish fever, vexation, jaundice, dark urine, stranguria with blood, pain with astringents, hematemesis, epistaxis, conjunctival congestion, swelling and pain, and sores and ulcers due to fire toxin; it can be used for treating sprain, contusion and pain. Compendium (compendium): it is used to treat hematemesis, epistaxis, bloody dysentery, hematorrhea, stranguria with blood, blood stasis, typhoid fever, headache, hernia, and fire injury. "
And (3) golden cypress: bitter taste and cold nature. It enters kidney and bladder meridians. Has the effects of clearing heat, eliminating dampness, purging pathogenic fire, removing toxic substances, and treating sore. Can be used for treating dysentery due to damp-heat pathogen, jaundice, leukorrhagia, stranguria caused by heat pathogen, tinea pedis, flaccidity, bone steaming, overstrain, night sweat, spermatorrhea, pyocutaneous disease, toxic swelling, eczema, and pruritus. Materia Medica Shi Yi: mainly treating pyretic herpes, insect sore, dysentery, hematochezia and moth killing; decoct it for diabetes. "medication method of medication": "treat sore pain intolerable. "
Coptis chinensis: bitter taste and cold nature. It enters heart, spleen, stomach, liver, gallbladder and large intestine meridians. Has the effects of clearing heat, eliminating dampness, purging pathogenic fire and removing toxic substances. It is used for treating damp-heat distention and fullness, emesis, acid regurgitation, dysentery, jaundice, hyperpyrexia, excessive heart-fire, vexation, insomnia, hematemesis, epistaxis, conjunctival congestion, toothache, thirst, carbuncle, and furuncle; it can be used for treating eczema, and purulence in ear canal. Jiu Huang is good at clearing heat from upper energizer. Rihuazi Ben Cao: for five kinds of work and seven kinds of injuries, it can tonify qi and relieve pain in the heart and abdomen. Palpitation, restlessness, moistening heart and lung, fleshy and arresting bleeding; sores and scabies, night sweats and diseases caused by heat in the daytime; the pork tripe is steamed into pills, which is indicated for infantile malnutrition. "
Mint: pungent taste and cool nature. It enters lung and liver meridians. Has the effects of dispelling wind and heat, clearing head and eyes, relieving sore throat, promoting eruption, soothing liver and promoting qi circulation. Can be used for treating wind-heat type common cold, early stage epidemic febrile disease, wind-heat type headache, conjunctival congestion, lacrimation, laryngopharynx swelling and pain, measles without adequate eruption, pruritus, stagnation of qi due to depression of the liver, chest distress, costalgia, summer feeling of summer heat and damp turbidity, abdominal pain, emesis, and diarrhea. Treatise on herb Property: ' go angry, send out toxic sweat, break blood and stop dysentery, and benefit joints. "
Oxytropis rachii is: slightly bitter taste and cold nature; is toxic. Has the effects of clearing away heat and toxic materials, promoting granulation, healing sore, astringing pulse, stopping bleeding, and relieving constipation. Can be used for treating pestilence and poisoning.
Fructus Terminaliae Billericae: sweet and astringent taste, mild in nature. Has the effects of clearing away heat and toxic materials, regulating diseases, astringing and nourishing blood. Can be used for treating various fever, dysentery, impetigo (Tibetan medicine name, not impetigo), liver and gallbladder diseases, and asthenia after illness.
Tea oil: sweet and bitter in taste and cool in nature. Has the effects of clearing away heat and toxic materials, moistening the intestines and killing parasites. Can be used for treating abdominal pain due to eruptive disease, constipation, ascaris abdominal pain, ascaris intestinal obstruction, scabies, and fire injury. The agricultural government's complete book: treat scabies and remove damp-heat. "
Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:
the invention uses the scutellaria as the monarch, enters the upper jiao to clear away heart fire, cools blood and detoxifies; ministerial drugs are matched with coptis, phellodendron and gardenia, the coptis detoxifying decoction is taken to have the effect of bitter cold and direct folding, so that fire toxin is cleared, and the carbuncle, swelling and furuncle toxin caused by heat toxin accumulation and muscle striae are treated; the mint has the functions of soothing the liver, promoting the circulation of qi, promoting eruption and relieving itching; terminalia chebula is a traditional medicine of Tibetan, is a dry mature fruit of Terminalia bellirica of Combretaceae, and has the effects of clearing heat and detoxicating, astringing and nourishing blood, and jointly playing the effects of nourishing blood and activating blood circulation, and removing blood stasis and relieving pain; the Oxytropis is grown in dry grassland with altitude of 3300-5300m and hillside grassland, and has effects of clearing away heat and toxic materials, promoting granulation, and healing sore, and is used as medicine for removing toxic substance and treating sore; the tea oil can cooperate with the medicines, so that the medicines supplement each other, and the effects of diminishing inflammation, relieving itching, cooling blood, removing toxicity, dissipating blood stasis, relieving swelling, activating blood circulation and relieving pain are achieved; the medicine can be prepared into external preparations, so that the medicine efficacy can directly reach the focus of infection, the curative effect can be exerted, and the stomach can be prevented from being injured by bitter and cold after oral administration.
According to the invention, after medicinal materials are soaked, the subsequent ethanol extraction can be facilitated, soluble impurities of the medicinal materials are removed, the remaining medicinal materials are added into tea oil to be decocted, and the tea oil is decocted to cooperate with the medicines to jointly play roles in diminishing inflammation, relieving itching, cooling blood, detoxifying, dissipating stasis, relieving swelling, activating blood circulation and relieving pain.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are conventional products which are not indicated by manufacturers and are commercially available.
It should be noted that, in the present application, the embodiments and features of the embodiments may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
The invention provides medicinal oil which comprises the following raw materials in parts by weight: 20-40 parts of scutellaria baicalensis, 20-40 parts of gardenia, 20-40 parts of phellodendron, 10-30 parts of coptis chinensis, 20-40 parts of mint, 5-25 parts of oxytropis, 5-25 parts of fructus terminaliae billericae and 450-560 parts of tea oil. The invention is based on the Su Wen, the true essentiality treatise: all sores and itching sores belong to the heart, and the scutellaria baicalensis is mainly used as the monarch drug and enters the upper-jiao to clear away heart fire, cool blood and remove toxicity; ministerial drugs are matched with coptis, phellodendron and gardenia, the coptis detoxification decoction is taken to have the effect of bitter cold and direct folding, so that fire toxin is cleared, and the carbuncle, swelling and furuncle toxin caused by heat toxin accumulation and muscle striae are treated; the mint has the effects of soothing the liver, promoting the circulation of qi, promoting eruption and relieving itching; terminalia chebula is a traditional medicine of Tibetan, is a dry mature fruit of Terminalia bellirica of Combretaceae, and has the effects of clearing heat and detoxicating, astringing and nourishing blood, and jointly playing the effects of nourishing blood and activating blood circulation, and removing blood stasis and relieving pain; oxytropis is grown in dry grassland with altitude of 3300-5300m and hillside grassland, and has effects of clearing away heat and toxic materials, promoting granulation, and healing sore, and is used as medicine for removing toxic substance and treating sore; the tea oil can cooperate with the medicines, so that the medicines supplement each other, and the effects of diminishing inflammation, relieving itching, cooling blood, removing toxicity, dissipating blood stasis, relieving swelling, activating blood circulation and relieving pain are achieved; the external preparation can make the efficacy of the medicine directly reach the focus of infection, exert curative effect and avoid stomach injury caused by bitter and cold in oral administration. In addition, the medicinal oil can be applied to mosquito bites, has the effects of relieving itching and detoxifying, and effectively relieves red, swollen, itchy and painful skin at the bitten positions.
In some embodiments of the present invention, the medicinal oil comprises the following raw materials in parts by weight: 25 parts of scutellaria baicalensis, 25 parts of gardenia, 25 parts of golden cypress, 15 parts of coptis chinensis, 25 parts of mint, 10 parts of oxytropis, 10 parts of fructus terminaliae billericae and 480 parts of tea oil.
In some embodiments of the present invention, the medicinal oil comprises the following raw materials by weight: 30 parts of scutellaria baicalensis, 30 parts of gardenia, 30 parts of golden cypress, 20 parts of coptis chinensis, 30 parts of mint, 15 parts of oxytropis, 15 parts of fructus terminaliae billericae and 510 parts of tea oil.
In some embodiments of the present invention, the medicinal oil comprises the following raw materials in parts by weight: 34 parts of scutellaria baicalensis, 35 parts of gardenia, 35 parts of golden cypress, 25 parts of coptis chinensis, 35 parts of mint, 20 parts of oxytropis, 20 parts of myrobalan and 530 parts of tea oil.
The invention also provides a preparation method of the medicinal oil, which comprises the following steps: crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, semen Oxytropis and fructus Chebulae, soaking in water, and taking out; adding ethanol into the soaked raw materials, heating and refluxing for extraction to obtain residues; adding tea oil into the residue, decocting, and filtering to obtain medicinal oil product. According to the invention, after the medicinal materials are soaked, the subsequent ethanol extraction can be facilitated, the soluble impurities are removed, the rest medicinal materials are added into the tea oil for decoction, and the tea oil is decocted to cooperate with the medicines to play roles of diminishing inflammation, relieving itching, cooling blood, removing toxicity, dissipating blood stasis, relieving swelling, promoting blood circulation and relieving pain.
In some embodiments of the present invention, the raw materials are crushed and then soaked for 20-60min. After soaking, water-soluble impurities in the subsequent medicines can be conveniently removed in water, and when the rest medicinal materials are heated and extracted by subsequent ethanol, some resin and fat-soluble impurities in the medicinal materials can be removed.
In some embodiments of the invention, the ethanol is present at a concentration of 50-70% by volume. The extraction results are optimal at this concentration.
In some embodiments of the present invention, the heating reflux extraction is specifically heating to 55-75 deg.C for 1-3h. The ethanol is heated and refluxed for extraction at the temperature, so that the ethanol can be volatilized conveniently, and fat-soluble impurities are taken away.
In some embodiments of the present invention, the residue is decocted for 3-5h after adding tea oil. After the tea oil is heated and decocted for the time, the medicine properties of the medicines can be conveniently permeated into the tea oil, so that the medicine properties are blended.
In some embodiments of the present invention, the temperature for the above-mentioned heating and decocting is 90-110 ℃.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
A preparation method of medicinal oil comprises the following steps:
the raw materials comprise: 20g of scutellaria baicalensis, 20g of gardenia, 20g of golden cypress, 10g of coptis chinensis, 20g of mint, 5g of oxytropis, 5g of fructus terminaliae billericae and 450g of tea oil.
Crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, fructus Oxytropis and fructus Chebulae, adding water, soaking for 20min, and taking out;
adding 50% ethanol into the soaked raw materials, heating to 55 deg.C, reflux extracting for 1h to obtain residue;
adding tea oil into the residue, heating to 90 deg.C, decocting for 3 hr, and filtering to obtain medicinal oil product.
Example 2
A preparation method of medicinal oil comprises the following steps:
the raw materials comprise: 22g of scutellaria baicalensis, 22g of cape jasmine, 22g of golden cypress, 12g of coptis chinensis, 22g of mint, 7g of oxytropis, 7g of fructus terminaliae billericae and 465g of tea oil.
Crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, fructus Oxytropis and fructus Chebulae, adding water, soaking for 30min, and taking out;
adding 55% ethanol into the soaked materials, heating to 60 deg.C, reflux extracting for 1.5 hr to obtain residue;
adding tea oil into the residue, heating to 95 deg.C, decocting for 3.5 hr, and filtering to obtain medicinal oil product.
Example 3
A preparation method of medicinal oil comprises the following steps:
the raw materials comprise: 25g of scutellaria baicalensis, 25g of cape jasmine, 25g of golden cypress, 15g of coptis chinensis, 25g of mint, 10g of oxytropis, 10g of fructus terminaliae billericae and 480g of tea oil.
Crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, semen Oxytropis and fructus Chebulae, adding water, soaking for 30min, and taking out;
adding 60% ethanol into the soaked raw materials, heating to 65 deg.C, reflux extracting for 2 hr to obtain residue;
adding tea oil into the residue, heating to 100 deg.C, decocting for 4 hr, and filtering to obtain medicinal oil product.
Example 4
A preparation method of medicinal oil comprises the following steps:
the raw materials comprise: 30g of scutellaria baicalensis, 30g of cape jasmine, 30g of golden cypress, 20g of coptis chinensis, 30g of mint, 15g of oxytropis, 15g of fructus terminaliae billericae and 510g of tea oil.
Crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, semen Oxytropis and fructus Chebulae, adding water, soaking for 30min, and taking out;
adding 60% ethanol into the soaked raw materials, heating to 65 deg.C, reflux extracting for 2 hr to obtain residue;
adding tea oil into the residue, heating to 100 deg.C, decocting for 4 hr, and filtering to obtain medicinal oil product.
Example 5
A preparation method of medicinal oil comprises the following steps:
the raw materials comprise: 34g of scutellaria baicalensis, 35g of cape jasmine, 35g of golden cypress, 25g of coptis chinensis, 35g of mint, 20g of oxytropis, 20g of fructus terminaliae billericae and 530g of tea oil.
Crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, fructus Oxytropis and fructus Chebulae, adding water, soaking for 40min, and taking out;
adding 60% ethanol into the soaked raw materials, heating to 65 deg.C, reflux extracting for 2 hr to obtain residue;
adding tea oil into the residue, heating to 100 deg.C, decocting for 4 hr, and filtering to obtain medicinal oil product.
Example 6
A preparation method of medicinal oil comprises the following steps:
the raw materials comprise: 38g of scutellaria baicalensis, 38g of gardenia, 38g of golden cypress, 28g of coptis chinensis, 38g of mint, 23g of oxytropis, 23g of fructus terminaliae billericae and 550g of tea oil.
Crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, semen Oxytropis and fructus Chebulae, adding water, soaking for 50min, and taking out;
adding 65% ethanol into the soaked raw materials, heating to 70 deg.C, reflux extracting for 2.5 hr to obtain residue;
adding tea oil into the residue, heating to 105 deg.C, decocting for 4.5h, and filtering to obtain medicinal oil product.
Example 7
A preparation method of medicinal oil comprises the following steps:
the raw materials comprise: 40g of scutellaria baicalensis, 40g of cape jasmine, 40g of golden cypress, 30g of coptis chinensis, 40g of mint, 25g of oxytropis, 25g of fructus terminaliae billericae and 560g of tea oil.
Crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, semen Oxytropis and fructus Chebulae, adding water, soaking for 60min, and taking out;
adding 70% ethanol into the soaked raw materials, heating to 75 deg.C, reflux extracting for 3 hr to obtain residue;
adding tea oil into the residue, heating to 110 deg.C, decocting for 5 hr, and filtering to obtain medicinal oil product.
Examples of the experiments
The traumatic injury patients 700 selected from 2018.3-2020.7 and aged 18-55 years were divided into 7 groups, and the medicinal oils prepared in examples 1-7 were used for treating each group of patients respectively. Treatment is divided into effective, improved and ineffective. Effective is that the body heals after treatment with the medicinal oil prepared in the present application; after the treatment by the medicinal oil prepared by the application, the disease condition is improved, but the disease is not cured; the ineffectiveness is that the disease condition is not changed after the treatment by the medicinal oil prepared by the application. The treatment is performed 3 times a day, and each time by massaging for 5-10min. The results are shown in Table 1.
TABLE 1
Group of | Effective/human | Good turning/human | Invalid/human |
Group 1 | 75 | 21 | 4 |
2 groups of | 77 | 20 | 3 |
3 groups of | 83 | 17 | 0 |
4 groups of | 89 | 11 | 0 |
5 groups of | 87 | 13 | 0 |
6 groups of | 80 | 17 | 3 |
7 groups of | 81 | 18 | 1 |
The table 1 is analyzed and compared, and the effective rate of the medicinal oil prepared by the application to the patients with the traumatic injuries is high, and the treatment condition of the patients with the traumatic injuries is good; analysis of the control groups 1-7 shows that the best results are seen for groups 3-5, but the highest efficiency is seen for group 4.
Typical cases are as follows:
1. in 18 years old for a certain Zhao, the male is aged 18 years, and 7 months and 4 in 2018, because of the pain of beating with classmates, the wrist is strained, and the strained part is red, swollen and painful, the cold compress is firstly carried out, then the medicinal oil prepared in the application example 3 is used for rubbing and massaging the affected part, the pain is relieved after the patient keeps for 1 day for 3 times every day, and the wrist is healed after 3 days.
2. Von onto a mammal: the female is 25 years old, and walks in 2018, 8 and 11 days, because the female wears high-heeled shoes to fall down carelessly, sprains ankles, and sprains the ankle to have red, swollen and painful parts and cannot walk, after cold compress treatment, the female rubs and massages at affected parts by using the medicinal oil prepared in the application example 4, the female lasts for 3 times every day, the pain is relieved after insisting on for 3 days, and the female can normally walk after lasting for 7 days.
3. When a woman is 24 years old, and in 2019, 6 and 9 days, the arm is accidentally injured by bruising, a large dark green part is left on the arm, the hand is numb, and the arm cannot move freely, the medicinal oil prepared in the embodiment 5 of the application is used for massaging the dark green part of the arm, 3 times are carried out every day, after 7 days, only a little mark is left, and after 3 days, the bruised green part disappears.
4. Yellow certain: a female is 36 years old, and is bitten by mosquitoes in 8 months and 1 day in 2019 in the evening when walking, the skin is red, swollen, itching and swollen, the medicinal oil prepared in the embodiment 1 of the application is used for massaging the position of the wrapped block, the itching of the wrapped block is relieved after the massage, and the red, swollen and cleared after 1 hour.
5. Ran to a certain ratio: a man 21 years old is stumbled by a person and the knee bumps into the ground when playing basketball in 2019, 12 months and 17 days, the knee is red, swollen and painful, the medicine oil prepared in the embodiment 2 of the application is used for massaging the knee in a weak way for 3 times a day after lasting for 3 days, the pain is relieved, the knee can move freely, and the man can be healed after lasting for 4 days.
6. The following steps: a man is 40 years old, in 2020, 1 month and 7 days, when heavy objects are moved, the waist is sprained and cannot stand up, and only the man can bend down to walk, the medicinal oil prepared in the application example 5 is used for rubbing and massaging an affected part, 3 times a day, after 3 days, the pain is improved, the waist can stand up, and after 3 days, the man can completely recover.
7. Millet certain: a man 51 years old is in 3 months and 24 days in 2020, the toe is injured by a brick carelessly, the nail is congested, the toe is red and swollen, after cold compress, the toe is massaged by using the medicinal oil prepared in the test 6, 3 times a day, the toe condition is improved after 7 days, and the toe is not painful any more after 10 days.
8. Song Dynasty, female 29 years old, 4 months and 4 days in 2020, large dark blue leaves remained in the place because of rock climbing and falling, the medicinal oil prepared in example 4 of this application was used to rub and massage the affected part 3 times a day, and after 3 days of persistence, the pain was relieved, and after 7 days of persistence, the pain was no longer relieved on the outer side of the thigh.
9. Zhou-chi: a woman 43 years old, in 2020, 6 months and 15 days, when moving heavy objects, sprains the waist, has difficulty in enduring the pain of the waist, can only lie aslant on the bed, after the plaster treatment is ineffective, the affected part is massaged by the medicinal oil prepared in the application example 6, 3 times a day, after 3 days, the pain is improved, the affected part can get out of the bed, and after 7 days, the affected part is completely cured.
In summary, the present invention is based on the Suzu-Zhenzheng treatise: all sores with pain and itching belong to the heart, and the scutellaria baicalensis is mainly used as the monarch drug to enter the upper jiao to clear away heart fire, cool blood and remove toxicity; ministerial drugs are matched with coptis, phellodendron and gardenia, the coptis detoxification decoction is taken to have the effect of bitter cold and direct folding, so that fire toxin is cleared, and the carbuncle, swelling and furuncle toxin caused by heat toxin accumulation and muscle striae are treated; the mint has the effects of soothing the liver, promoting the circulation of qi, promoting eruption and relieving itching; terminalia chebula is a traditional medicine of Tibetan, is a dry mature fruit of Terminalia bellirica of Combretaceae, and has the effects of clearing heat and detoxicating, astringing and nourishing blood, and jointly playing the effects of nourishing blood and activating blood circulation, and removing blood stasis and relieving pain; the Oxytropis is grown in dry grassland with altitude of 3300-5300m and hillside grassland, and has effects of clearing away heat and toxic materials, promoting granulation, and healing sore, and is used as medicine for removing toxic substance and treating sore; the tea oil can cooperate with the medicines, so that the medicines supplement each other, and the effects of diminishing inflammation, relieving itching, cooling blood, removing toxicity, dissipating blood stasis, relieving swelling, activating blood circulation and relieving pain are achieved; the external preparation can make the efficacy of the medicine directly reach the focus of infection, exert curative effect and avoid stomach injury caused by bitter and cold in oral administration. In addition, the medicinal oil can be applied to mosquito bites, has the effects of relieving itching and detoxifying, and effectively relieves red, swollen, itchy and painful skin at the bitten positions. According to the invention, after medicinal materials are soaked, the subsequent ethanol extraction can be facilitated, soluble impurities of the medicinal materials are removed, the remaining medicinal materials are added into tea oil to be decocted, and the tea oil is decocted to cooperate with the medicines to jointly play roles in diminishing inflammation, relieving itching, cooling blood, detoxifying, dissipating stasis, relieving swelling, activating blood circulation and relieving pain.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Claims (10)
1. The medicinal oil for treating traumatic injury is characterized by comprising the following raw materials in parts by weight: 20-40 parts of scutellaria baicalensis, 20-40 parts of gardenia, 20-40 parts of golden cypress, 10-30 parts of coptis chinensis, 20-40 parts of mint, 5-25 parts of oxytropis, 5-25 parts of fructus terminaliae billericae and 450-560 parts of tea oil.
2. The medicinal oil for treating traumatic injury according to claim 1, which is prepared from the following raw materials in parts by weight: 25 parts of scutellaria baicalensis, 25 parts of gardenia, 25 parts of golden cypress, 15 parts of coptis chinensis, 25 parts of mint, 10 parts of oxytropis, 10 parts of fructus terminaliae billericae and 480 parts of tea oil.
3. The medicinal oil for treating traumatic injury according to claim 1, which is prepared from the following raw materials in parts by weight: 30 parts of scutellaria baicalensis, 30 parts of gardenia, 30 parts of golden cypress, 20 parts of coptis chinensis, 30 parts of mint, 15 parts of oxytropis, 15 parts of fructus terminaliae billericae and 510 parts of tea oil.
4. The medicinal oil for treating traumatic injury according to claim 1, which is prepared from the following raw materials in parts by weight: 34 parts of scutellaria baicalensis, 35 parts of gardenia, 35 parts of golden cypress, 25 parts of coptis chinensis, 35 parts of mint, 20 parts of oxytropis, 20 parts of fructus terminaliae billericae and 530 parts of tea oil.
5. The preparation method of the medicinal oil for treating traumatic injury according to any one of claims 1 to 4, comprising the following steps:
crushing Scutellariae radix, fructus Gardeniae, cortex Phellodendri, coptidis rhizoma, herba Menthae, semen Oxytropis and fructus Chebulae, soaking in water, and taking out;
adding ethanol into the soaked raw materials, heating and refluxing for extraction to obtain residues;
adding tea oil into the residue, decocting, and filtering to obtain medicinal oil product.
6. The preparation method of medicinal oil for treating traumatic injury according to claim 5, wherein the raw materials are soaked for 20-60min after being crushed.
7. The method for preparing medicinal oil for treating traumatic injury according to claim 5, wherein the volume concentration of ethanol is 50-70%.
8. The preparation method of the medicinal oil for treating traumatic injury according to claim 5, wherein the heating reflux extraction is specifically heating to 55-75 ℃ for 1-3h.
9. The method for preparing medicinal oil for treating traumatic injury according to claim 5, wherein the residue is added with tea oil and then decocted for 3-5h.
10. The method for preparing medicinal oil for treating traumatic injury according to claim 5, wherein the temperature for heating and decocting is 90-110 ℃.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110990842.6A CN113577166B (en) | 2021-08-26 | 2021-08-26 | Medicinal oil and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110990842.6A CN113577166B (en) | 2021-08-26 | 2021-08-26 | Medicinal oil and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN113577166A CN113577166A (en) | 2021-11-02 |
CN113577166B true CN113577166B (en) | 2022-11-11 |
Family
ID=78239752
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202110990842.6A Active CN113577166B (en) | 2021-08-26 | 2021-08-26 | Medicinal oil and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113577166B (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101181372A (en) * | 2007-11-17 | 2008-05-21 | 甘肃奇正藏药有限公司 | Method for preparing alcohol extract of tibetan medicine Qing-peng slurry |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1056298C (en) * | 1996-12-31 | 2000-09-13 | 佛山市中医院 | External use medicine for treating soft tissue injury and its producing method |
CN105031543A (en) * | 2015-08-27 | 2015-11-11 | 刘忠波 | Traditional Chinese medicine tincture for treating traumatic injuries and synovitis |
CN113332350A (en) * | 2021-07-13 | 2021-09-03 | 重庆兴皕堂生物科技有限公司 | Compound herbal antibacterial liquid and preparation process and application thereof |
-
2021
- 2021-08-26 CN CN202110990842.6A patent/CN113577166B/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101181372A (en) * | 2007-11-17 | 2008-05-21 | 甘肃奇正藏药有限公司 | Method for preparing alcohol extract of tibetan medicine Qing-peng slurry |
Non-Patent Citations (1)
Title |
---|
应用MEBO湿润烧伤膏治疗外伤性软组织擦伤;杨洪菊,等;《实用医技杂志》;20021020(第10期);第751-752页 * |
Also Published As
Publication number | Publication date |
---|---|
CN113577166A (en) | 2021-11-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101804166B (en) | Traditional Chinese medicine composition for treating dermatitis and eczema of infants | |
CN104667244B (en) | A kind of Pediluvium composition for treating primary dysmenorrhea | |
CN103463356B (en) | The Chinese medicine composition for the treatment of yang deficiency arthromyodynia | |
CN102626505B (en) | Massaging paste based on Chinese medicinal herbs and preparation method thereof | |
CN104258278A (en) | Gushangling (for bone injury) spray | |
CN110314216A (en) | It is a kind of to treat Bones and joints, plaster of soft tissue disease pain and preparation method thereof | |
CN105920570A (en) | Quick-acting externally applied traditional Chinese medicine for treating rheumatoid bone diseases and preparation method | |
CN113577166B (en) | Medicinal oil and preparation method thereof | |
CN104083568A (en) | Miao medicine plaster for ostealgia and preparation method thereof | |
CN107412491A (en) | A kind of externally applied ointment for treating hyperosteogeny patch and preparation method thereof | |
CN113041323A (en) | Medicine for treating bone fracture | |
CN111991527A (en) | Foot medicated bath formula and preparation process thereof | |
CN106039174A (en) | Traditional Chinese medicinal liquor for treating osteoarthrosis | |
CN110013513B (en) | External gel for treating rheumatic ostealgia and preparation method thereof | |
CN105412395A (en) | Traditional Chinese medicine composition for treating hyperostosis and preparation method thereof | |
CN106039257A (en) | Traditional Chinese medicine mud-moxibustion ointment and preparation method thereof | |
CN105770115A (en) | Traditional Chinese medicine ointment for treating eczema | |
CN105362944A (en) | Traditional Chinese medicine ointment for treating orthopedics sprain and contusion | |
CN104758830A (en) | Traditional Chinese medicine composition for treating bone disease and skin injury and preparation method of traditional Chinese medicine composition | |
CN104257995A (en) | External application patch for treating traumatic injuries and preparation method thereof | |
CN117771317A (en) | Traditional Chinese medicine composition for treating dialysis-related muscle spasm | |
CN116920064A (en) | Traditional Chinese medicine formula for treating rheumatic bone diseases and processing method thereof | |
CN110237184A (en) | It is a kind of to treat traumatic injury, arthralgic traditional Chinese medicine plaster and preparation method thereof | |
CN113652863A (en) | Health-care underwear with health-care and health-preserving functions and hypertension conditioning functions and production method thereof | |
CN115554227A (en) | Medicinal liquor for treating traumatic injury |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |