CN113521877A - A purification equipment for producing cross-linking modification is with hyaluronic acid - Google Patents
A purification equipment for producing cross-linking modification is with hyaluronic acid Download PDFInfo
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- CN113521877A CN113521877A CN202110884792.3A CN202110884792A CN113521877A CN 113521877 A CN113521877 A CN 113521877A CN 202110884792 A CN202110884792 A CN 202110884792A CN 113521877 A CN113521877 A CN 113521877A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D36/00—Filter circuits or combinations of filters with other separating devices
- B01D36/04—Combinations of filters with settling tanks
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D36/00—Filter circuits or combinations of filters with other separating devices
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Abstract
The invention discloses a purification device for producing hyaluronic acid for cross-linking modification, which comprises a stirring and feeding mechanism, a turnover cleaning mechanism, a conveying mechanism, a first storage box, a second storage box, a settling tank and a filter screen, wherein the stirring and feeding mechanism is arranged on the stirring and feeding mechanism; a cleaning block is arranged in the sedimentation tank; the overturning cleaning mechanism is used for overturning the settling tank to pour out sediment and liquid in the settling tank, the sediment falls onto the filter screen, the liquid flows into the first storage box from meshes of the filter screen, meanwhile, the overturning of the settling tank enables the cleaning block to scrape off the sediment remained on the inner wall of the settling tank, and after the overturning is finished, the overturning cleaning mechanism scrapes off the sediment remained on the cleaning block; according to the invention, the turntable is arranged on the stirring rod, so that alcohol can be slowly added while stirring; the invention can complete the overturning of the settling tank and the cleaning of the residual sediment in the settling tank through the first electric pole, has smart and simple structure, reduces the manufacturing cost and simultaneously avoids the influence of the residual sediment on the subsequent work.
Description
Technical Field
The invention relates to the technical field of biological polysaccharide extraction, in particular to a purification device for producing hyaluronic acid for cross-linking modification.
Background
Hyaluronic acid, also known as hyaluronic acid, is a disaccharide glycosaminoglycan composed of D-glucuronic acid and N-acetylglucosamine, which is cross-linked and modified to be widely used in cosmetic products and tissue augmentation products. In recent years, the demand of hyaluronic acid is gradually increased, and the current domestic method for producing hyaluronic acid is gradually changed from an animal tissue extraction method to a microbial fermentation method; when the microorganism fermentation method is adopted for purification, the fermentation liquor is required to react in a precipitation tank to generate precipitates, and then the precipitation tank is poured to collect the precipitates; the sediment is easy to remain in the sedimentation tank during production, which is not beneficial to quantitative control during production and is easy to influence the purification effect.
Disclosure of Invention
The invention aims to provide a purification device for producing hyaluronic acid for crosslinking modification, which aims to solve the problem that the residue of sediment in a precipitation tank influences the purification effect during production, which is proposed in the background art.
In order to solve the technical problem, the purification equipment for producing hyaluronic acid for cross-linking modification provided by the invention comprises a stirring and feeding mechanism, an overturning and cleaning mechanism, a conveying mechanism, a first storage tank, a second storage tank, a sedimentation tank and a filter screen; a cleaning block is arranged in the sedimentation tank; the first storage tank is positioned below the sedimentation tank, and the second storage tank is positioned on one side of the first storage tank; the stirring and feeding mechanism is used for stirring the liquid in the settling tank and intermittently adding alcohol; the overturning cleaning mechanism is used for overturning the settling tank to pour out sediment and liquid in the settling tank, the sediment falls onto the filter screen, the liquid flows into the first storage box from meshes of the filter screen, meanwhile, the overturning of the settling tank enables the cleaning block to scrape off the sediment remained on the inner wall of the settling tank, and after the overturning is finished, the overturning cleaning mechanism scrapes off the sediment remained on the cleaning block; the conveying mechanism is used for conveying the sediment on the filter screen to the second storage tank for dissolution in the solvent.
Preferably, the stirring and feeding mechanism comprises a first bracket, an alcohol tank, a stirring rod and a working motor; the first support is fixedly connected with an alcohol tank, and a first cavity is arranged in the alcohol tank; the stirring rod is rotationally connected with the alcohol tank, a rotary table is fixedly connected to the stirring rod, and a sealing ring is arranged between the rotary table and the first cavity; the rotary plate is provided with a first through hole, the lower end face of the alcohol tank is provided with a second through hole, and the first through hole and the second through hole are aligned when the rotary plate rotates to a working position and used for adding alcohol into the precipitation tank; the upper end surface of the alcohol tank is connected with a feeding sliding block in a sliding manner; the working motor is fixedly connected with the upper end of the alcohol tank, and the output shaft of the working motor is fixedly connected with the stirring rod.
Preferably, the overturning cleaning mechanism comprises a second bracket, a first electric pole, a round rod, an unlocking block, a cleaning plate, a locking block and a first connecting rod; the second bracket is fixedly connected with a rack; the first electric pole is fixedly connected with one end of the second support, and the telescopic end of the first electric pole is fixedly connected with an installation block; the round rod is rotatably connected with one end of the mounting block; the middle part of the round rod is fixedly connected with a reversing wheel, the reversing wheel is meshed with the rack in the retraction process of the first electric pole, one end of the round rod is fixedly connected with an unlocking block, a first inclined plane is arranged on the unlocking block, and one end of the unlocking block is fixedly connected with the sedimentation tank; a sedimentation cavity is arranged in the sedimentation tank, the cleaning block is connected with the sedimentation cavity in a sliding manner, one end of a cotton rope is connected with the bottom of the sedimentation cavity, and the other end of the cotton rope is fixedly connected with the lower end face of the cleaning block; the cleaning plate is connected with one end of the second support in a sliding mode, a rectangular groove is formed in the cleaning plate, a sliding block is connected in the rectangular groove in a sliding mode, a fixed rod is fixedly connected in the rectangular groove and is connected with the sliding block in a sliding mode, a first spring is sleeved on the fixed rod, one end of the first spring is fixedly connected with the sliding block, the other end of the first spring is fixedly connected with the rectangular groove, and the first spring forces the cleaning plate to move towards one side close to the sedimentation tank; one end of the cleaning plate is provided with a locking groove, the locking block is in sliding connection with the locking groove through a protrusion arranged on the locking block, one end of a second spring is fixedly connected with the protrusion, the other end of the second spring is fixedly connected with the locking groove, and the second spring forces the locking block to move towards the direction close to the second support; the locking block is respectively provided with a second inclined surface, a locking notch and a third inclined surface; one end of the cleaning plate is rotatably connected with a first connecting rod, and the first connecting rod is rotatably connected with the mounting block; the first electric pole is used for controlling the overturning of the settling tank and the popping and withdrawing of the cleaning plate; the cleaning block is matched with the thread rope to scrape the residual sediment on the side wall of the sedimentation chamber when the sedimentation tank is overturned, and the cleaning plate is used for scraping the residual sediment on the cleaning block when the sedimentation tank is overturned.
Preferably, the conveying mechanism comprises a third bracket, a second electric pole and a conveying motor; the third support is positioned on one side of the first storage box, the third support is connected with a conveying block in a sliding mode, the third support is connected with a screw rod in a rotating mode, and the conveying block is in matched transmission with the screw rod through a threaded hole formed in the conveying block; the second electric pole is fixedly connected with the conveying block, and the telescopic end of the second electric pole is detachably connected with the filter screen; the conveying motor is fixedly connected with the third support, and an output shaft of the conveying motor is fixedly connected with the screw.
Preferably, a sealing ring is arranged between the cleaning block and the side wall of the sedimentation chamber.
After adopting the structure, compared with the prior art, the invention has the following advantages: according to the invention, the turntable is arranged on the stirring rod, so that alcohol can be slowly added while stirring; the invention can complete the overturning of the settling tank and the cleaning of the residual sediment in the settling tank through the first electric pole, has smart and simple structure, reduces the manufacturing cost and simultaneously avoids the influence of the residual sediment on the subsequent work.
Drawings
FIG. 1 is a schematic three-dimensional structure of the present invention;
FIG. 2 is a schematic view of another perspective three-dimensional structure of the present invention;
FIG. 3 is a front view of the present invention;
FIG. 4 is a cross-sectional view taken along line A-A of FIG. 3 in accordance with the present invention;
FIG. 5 is a cross-sectional view taken along line B-B of FIG. 3 in accordance with the present invention;
FIG. 6 is a cross-sectional view taken along line C-C of FIG. 3 in accordance with the present invention;
fig. 7 is a three-dimensional structure diagram of the locking block of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
As shown in fig. 1 to 7, the purifying apparatus for producing hyaluronic acid for cross-linking modification of the present invention comprises a stirring and feeding mechanism 1, a turn-over cleaning mechanism 2, a conveying mechanism 3, a first storage tank 31, a second storage tank 32, a settling tank 4 and a strainer 5; a cleaning block 42 is arranged in the settling tank 4; the first storage tank 31 is positioned below the settling tank 4, and the second storage tank 32 is positioned at one side of the first storage tank 31; the stirring and feeding mechanism 1 is used for stirring the liquid in the settling tank 4 and intermittently adding alcohol; the overturning cleaning mechanism 2 is used for overturning the settling tank 4 to pour out sediments and liquid in the settling tank 4, the sediments fall onto the filter screen 5, the liquid flows into the first storage tank 31 from meshes of the filter screen 5, meanwhile, the overturning of the settling tank 4 enables the cleaning block 42 to scrape off the residual sediments on the inner wall of the settling tank 4, and after the overturning is finished, the overturning cleaning mechanism 2 scrapes off the residual sediments on the cleaning block 42; the conveying mechanism 3 is used for conveying the sediment on the filter screen 5 to the second storage tank 32 for dissolution in the solvent.
The stirring and feeding mechanism 1 comprises a first bracket 11, an alcohol tank 12, a stirring rod 13 and a working motor 14; the first support 11 is fixedly connected with the alcohol tank 12, and a first cavity 121 is arranged in the alcohol tank 12; the stirring rod 13 is rotatably connected with the alcohol tank 12, the stirring rod 13 is fixedly connected with a rotary disc 131, and a sealing ring is arranged between the rotary disc 131 and the first cavity 121; the turntable 131 is provided with a first through hole 1311, the lower end face of the alcohol tank 12 is provided with a second through hole 122, and when the turntable 131 rotates to the working position, the first through hole 1311 and the second through hole 122 are aligned to add alcohol into the precipitation tank 4; the upper end surface of the alcohol tank 12 is connected with a charging slide block 123 in a sliding way; the working motor 14 is fixedly connected with the upper end of the alcohol tank 12, and the output shaft of the working motor 14 is fixedly connected with the stirring rod 13; in particular, while the present embodiment changes the alcohol adding rate by controlling and changing the rotation speed of the rotating disc 131, in other embodiments, the first through hole 1311 may be provided as an annular groove, and the size of the annular groove may be changed by matching a spring and a stopper to change the alcohol adding rate.
The overturning cleaning mechanism 2 comprises a second bracket 21, a first electric pole 22, a round rod 23, an unlocking block 24, a cleaning plate 25, a locking block 26 and a first connecting rod 27; a rack 211 is fixedly connected to the second bracket 21; the first electric pole 22 is fixedly connected with one end of the second bracket 21, and the telescopic end of the first electric pole 22 is fixedly connected with a mounting block 221; the round rod 23 is rotatably connected with one end of the mounting block 221; the middle part of the round rod 23 is fixedly connected with a reversing wheel 231, the reversing wheel 231 is meshed with the rack 211 in the retraction process of the first electric pole 22, one end of the round rod 23 is fixedly connected with an unlocking block 24, a first inclined surface 241 is arranged on the unlocking block 24, and one end of the unlocking block 24 is fixedly connected with the sedimentation tank 4; a sedimentation cavity 41 is arranged in the sedimentation tank 4, the cleaning block 42 is connected with the sedimentation cavity 41 in a sliding way, one end of a cord 43 is connected with the bottom of the sedimentation cavity 41, and the other end of the cord 43 is fixedly connected with the lower end face of the cleaning block 42; the cleaning plate 25 is connected with one end of the second bracket 21 in a sliding manner, a rectangular groove 251 is arranged on the cleaning plate 25, a sliding block 252 is connected in the rectangular groove 251 in a sliding manner, a fixed rod 253 is fixedly connected in the rectangular groove 251, the fixed rod 253 is connected with the sliding block 252 in a sliding manner, a first spring 254 is sleeved on the fixed rod 253, one end of a first spring 254 is fixedly connected with the sliding block 252, the other end of the first spring 254 is fixedly connected with the rectangular groove 251, and the first spring 254 forces the cleaning plate 25 to move towards one side close to the sedimentation tank 4; one end of the cleaning plate 25 is provided with a locking groove 255, the locking block 26 is slidably connected with the locking groove 255 through a protrusion 264 arranged on the locking plate, one end of a second spring 256 is fixedly connected with the protrusion 264, the other end of the second spring 256 is fixedly connected with the locking groove 255, and the second spring 256 forces the locking block 26 to move towards the direction close to the second bracket 21; the locking block 26 is respectively provided with a second inclined surface 261, a locking notch 262 and a third inclined surface 263; one end of the cleaning plate 25 is rotatably connected with a first connecting rod 27, and the first connecting rod 27 is rotatably connected with the mounting block 221; the first electric pole 22 is used for controlling the overturning of the settling tank 4 and the ejection and retraction of the cleaning plate 25; the cleaning block 42 and the wire rope 43 are matched to scrape off the residual sediment on the side wall of the settling chamber 41 when the settling tank 4 is turned over, and the cleaning plate 25 is used for scraping off the residual sediment on the cleaning block 42 when the settling tank 4 is turned over; during specific work, because of the displacement of cleaning block 42 mainly relies on self gravity, multiplicable counter weight prevents its displacement and slowly influences efficiency, and cleaning block 42 is in the coplanar towards jar mouth one end and 4 jar mouths of gunbarrel 4 when the length of cotton rope 43 need guarantee that cleaning block 42 displacement distance is the biggest simultaneously, need notice 4 jar mouths of gunbarrel should be the horizontal terminal surface.
The conveying mechanism 3 comprises a third bracket 33, a second electric pole 34 and a conveying motor 35; the third bracket 33 is positioned on one side of the first storage box 31, the third bracket 33 is connected with a conveying block 331 in a sliding manner, the third bracket 33 is connected with a screw rod 332 in a rotating manner, and the conveying block 331 is in matched transmission with the screw rod 332 through a threaded hole arranged on the conveying block 331; the second electric pole 34 is fixedly connected with the conveying block 331, and the telescopic end of the second electric pole 34 is detachably connected with the filter screen 5; the conveying motor 35 is fixedly connected with the third bracket 33, and an output shaft of the conveying motor 35 is fixedly connected with the screw 332.
And a sealing ring is arranged between the cleaning block 42 and the side wall of the sedimentation cavity 41.
The working process of the purification equipment for producing the hyaluronic acid for crosslinking modification of the embodiment of the invention is as follows:
firstly, adding a proper amount of 90-99% alcohol into an alcohol tank 12 through a feeding slide block 123, pouring a proper amount of streptococcus zooepidemicus AWA008 fermentation liquor into a precipitation tank 4, and pouring a proper amount of sodium chloride solution into a second storage box 32, wherein the equipment state is shown in figure 1; the working motor 14 is started to drive the stirring rod 13 and the rotating disc 131 to rotate, the stirring rod 13 continuously stirs the fermentation liquid, and simultaneously, when the rotating disc 131 rotates to the working position shown in fig. 6 where the first through hole 1311 is aligned with the second through hole 122, a certain amount of liquid in the alcohol tank 12 flows into the precipitation tank 4;
after a certain time, the sediment in the settling tank 4 is separated out, the working motor 14 is stopped, the first electric pole 22 is changed into a retraction state from the extension state, in the process, the reversing wheel 231 is meshed with the rack 211, so that the reversing wheel 231 drives the unlocking block 24 and the settling tank 4 to rotate, the liquid and the sediment in the settling tank 4 are poured out, the liquid flows into the first storage tank 31, the sediment falls on the filter screen 5, meanwhile, the cleaning block 42 slowly slides towards the tank opening direction of the settling tank 4 to scrape the residual sediment on the inner wall of the settling tank 4, and in the process, the first connecting rod 27 pushes the sliding block 252 to compress the first spring 254 to slide towards the settling tank 4; after the first electric pole 22 retracts for a certain distance, the sedimentation tank 4 rotates 180 degrees, at the moment, the rope 43 pulls the cleaning block 42 to enable one end, facing the tank opening, of the cleaning block 42 to be positioned on the same plane as the tank opening of the sedimentation tank 4, and the tank opening of the sedimentation tank 4 and the uppermost end of the cleaning plate 25 are positioned on the same plane; then the first electric pole 22 is completely retracted, in the process, the first inclined surface 241 on the unlocking block 24 presses the second inclined surface 261 on the locking block 26, so that the locking block 26 compresses the second spring 256 to slide in the direction away from the second bracket 21, the locking notch 262 no longer locks the cleaning plate 25, and at the moment, the cleaning plate 25 moves towards the sedimentation tank 4 under the action of the first spring 254 to scrape off the residual sediment on the end surface of the cleaning block 42;
then the first electric pole 22 changes from retraction to extension, in the process, the first connecting rod 27 pulls the cleaning plate 25 to move away from the sedimentation tank 4, when the third inclined surface 263 on the locking block 26 is contacted with the second bracket 21, the second bracket 21 pushes the third inclined surface 263 to enable the locking block 26 to compress the second spring 256 to slide away from the second bracket 21, the cleaning plate 25 continues to move to clamp the second bracket 21 into the locking notch 262, at the moment, the first connecting rod 27 is completely extended, and the equipment is reset to the state shown in fig. 1;
then conveying mechanism 3 work, conveying motor 35 starts to make screw rod 332 rotatory, drives filter screen 5 and removes to second storage box 32 top suitable position, and second pole 34 stretches out and makes filter screen 5 sink in the sodium chloride solution, waits that conveying mechanism 3 resets after the precipitate dissolves on the filter screen 5, and liquid will get into subsequent handling in the second storage box 32.
The above description is only about the preferred embodiment of the present invention, but it should not be understood as limiting the claims, and the present invention may be modified in other structures, not limited to the above structures. In general, all changes which come within the scope of the invention as defined by the independent claims are intended to be embraced therein.
Claims (5)
1. The purifying equipment for producing the hyaluronic acid for cross-linking modification is characterized by comprising a stirring and feeding mechanism (1), a turnover cleaning mechanism (2), a conveying mechanism (3), a first storage tank (31), a second storage tank (32), a settling tank (4) and a filter screen (5); a cleaning block (42) is arranged in the settling tank (4); the first storage tank (31) is positioned below the sedimentation tank (4), and the second storage tank (32) is positioned on one side of the first storage tank (31); the stirring and feeding mechanism (1) is used for stirring the liquid in the settling tank (4) and intermittently adding alcohol; the overturning cleaning mechanism (2) is used for overturning the settling tank (4) to pour out sediment and liquid in the settling tank (4), the sediment falls onto the filter screen (5), the liquid flows into the first storage tank (31) from meshes of the filter screen (5), meanwhile, the overturning of the settling tank (4) enables the cleaning block (42) to scrape off residual sediment on the inner wall of the settling tank (4), and after the overturning is finished, the overturning cleaning mechanism (2) scrapes off residual sediment on the cleaning block (42); the conveying mechanism (3) is used for conveying the sediment on the filter screen (5) to the second storage tank (32) for dissolving in the solvent.
2. The purification apparatus for producing hyaluronic acid for cross-linking modification according to claim 1, wherein the stirring and feeding mechanism (1) comprises a first bracket (11), an alcohol tank (12), a stirring rod (13), and a working motor (14); the first support (11) is fixedly connected with the alcohol tank (12), and a first cavity (121) is arranged in the alcohol tank (12); the stirring rod (13) is rotatably connected with the alcohol tank (12), a rotary disc (131) is fixedly connected to the stirring rod (13), and a sealing ring is arranged between the rotary disc (131) and the first cavity (121); a first through hole (1311) is formed in the rotary disc (131), a second through hole (122) is formed in the lower end face of the alcohol tank (12), and when the rotary disc (131) rotates to the working position, the first through hole (1311) and the second through hole (122) are aligned to be used for adding alcohol into the settling tank (4); the upper end surface of the alcohol tank (12) is connected with a charging slide block (123) in a sliding way; the upper end of the working motor (14) is fixedly connected with the upper end of the alcohol tank (12), and the output shaft of the working motor (14) is fixedly connected with the stirring rod (13).
3. The purification apparatus for producing hyaluronic acid for cross-linking modification according to claim 1, wherein the inverted cleaning mechanism (2) comprises a second bracket (21), a first electric rod (22), a round rod (23), an unlocking block (24), a cleaning plate (25), a locking block (26), and a first connecting rod (27); a rack (211) is fixedly connected to the second bracket (21); one end of the first electric pole (22) is fixedly connected with one end of the second bracket (21), and the telescopic end of the first electric pole (22) is fixedly connected with a mounting block (221); the round rod (23) is rotatably connected with one end of the mounting block (221); the middle part of the round rod (23) is fixedly connected with a reversing wheel (231), the reversing wheel (231) is meshed with the rack (211) in the retraction process of the first electric pole (22), one end of the round rod (23) is fixedly connected with an unlocking block (24), a first inclined plane (241) is arranged on the unlocking block (24), and one end of the unlocking block (24) is fixedly connected with the settling tank (4); a sedimentation cavity (41) is arranged in the sedimentation tank (4), the cleaning block (42) is in sliding connection with the sedimentation cavity (41), one end of a thread rope (43) is connected with the bottom of the sedimentation cavity (41), and the other end of the thread rope (43) is fixedly connected with the lower end face of the cleaning block (42); the cleaning plate (25) is in sliding connection with one end of the second support (21), a rectangular groove (251) is formed in the cleaning plate (25), a sliding block (252) is connected in the rectangular groove (251) in a sliding mode, a fixing rod (253) is fixedly connected in the rectangular groove (251), the fixing rod (253) is in sliding connection with the sliding block (252), a first spring (254) is sleeved on the fixing rod (253), one end of the first spring (254) is fixedly connected with the sliding block (252), the other end of the first spring (254) is fixedly connected with the rectangular groove (251), and the first spring (254) forces the cleaning plate (25) to move towards one side close to the sedimentation tank (4); one end of the cleaning plate (25) is provided with a locking groove (255), the locking block (26) is in sliding connection with the locking groove (255) through a protrusion (264) arranged on the locking block, one end of a second spring (256) is fixedly connected with the protrusion (264), the other end of the second spring (256) is fixedly connected with the locking groove (255), and the second spring (256) forces the locking block (26) to move towards the direction close to the second support (21); the locking block (26) is respectively provided with a second inclined surface (261), a locking notch (262) and a third inclined surface (263); one end of the cleaning plate (25) is rotatably connected with a first connecting rod (27), and the first connecting rod (27) is rotatably connected with the mounting block (221); the first electric pole (22) is used for controlling the overturning of the settling tank (4) and the ejection and retraction of the cleaning plate (25); the cleaning block (42) and the wire rope (43) are matched to scrape off the residual sediment on the side wall of the settling chamber (41) when the settling tank (4) is turned over, and the cleaning plate (25) is used for scraping off the residual sediment on the cleaning block (42) when the settling tank (4) is turned over.
4. The purification apparatus for producing hyaluronic acid for cross-linking modification according to claim 1, wherein the transport mechanism (3) comprises a third bracket (33), a second electric pole (34) and a transport motor (35); the third support (33) is positioned on one side of the first storage box (31), the third support (33) is connected with a conveying block (331) in a sliding mode, the third support (33) is connected with a screw rod (332) in a rotating mode, and the conveying block (331) is in matched transmission with the screw rod (332) through a threaded hole formed in the conveying block (331); the second electric pole (34) is fixedly connected with the conveying block (331), and the telescopic end of the second electric pole (34) is detachably connected with the filter screen (5); the conveying motor (35) is fixedly connected with the third support (33), and an output shaft of the conveying motor (35) is fixedly connected with the screw (332).
5. The purification apparatus for producing hyaluronic acid for cross-linking modification according to claim 3, wherein a sealing ring is provided between the cleaning block (42) and the sidewall of the precipitation chamber (41).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110884792.3A CN113521877A (en) | 2021-08-03 | 2021-08-03 | A purification equipment for producing cross-linking modification is with hyaluronic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110884792.3A CN113521877A (en) | 2021-08-03 | 2021-08-03 | A purification equipment for producing cross-linking modification is with hyaluronic acid |
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| Publication Number | Publication Date |
|---|---|
| CN113521877A true CN113521877A (en) | 2021-10-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110884792.3A Pending CN113521877A (en) | 2021-08-03 | 2021-08-03 | A purification equipment for producing cross-linking modification is with hyaluronic acid |
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| CN (1) | CN113521877A (en) |
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| JPS5778989A (en) * | 1980-10-31 | 1982-05-17 | Hoxan Corp | Activated aludge treatment |
| CN105056787A (en) * | 2015-08-13 | 2015-11-18 | 山东天鹅棉业机械股份有限公司 | Mixer |
| CN206343143U (en) * | 2016-12-31 | 2017-07-21 | 福建福日特种材料有限公司 | A kind of mould wash mixer of Automatic-dumping |
| CN107088375A (en) * | 2017-03-27 | 2017-08-25 | 杭州盛格软控机电有限公司 | Dyestuff carrying method and its system |
| CN207085830U (en) * | 2017-06-23 | 2018-03-13 | 佛山市长江食品有限公司 | A kind of switching mechanism for mixing sugared machine |
| CN108745240A (en) * | 2018-06-06 | 2018-11-06 | 永城职业学院 | A kind of new chemical chemical waste liquid specification recovery processing device |
-
2021
- 2021-08-03 CN CN202110884792.3A patent/CN113521877A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5778989A (en) * | 1980-10-31 | 1982-05-17 | Hoxan Corp | Activated aludge treatment |
| CN105056787A (en) * | 2015-08-13 | 2015-11-18 | 山东天鹅棉业机械股份有限公司 | Mixer |
| CN206343143U (en) * | 2016-12-31 | 2017-07-21 | 福建福日特种材料有限公司 | A kind of mould wash mixer of Automatic-dumping |
| CN107088375A (en) * | 2017-03-27 | 2017-08-25 | 杭州盛格软控机电有限公司 | Dyestuff carrying method and its system |
| CN207085830U (en) * | 2017-06-23 | 2018-03-13 | 佛山市长江食品有限公司 | A kind of switching mechanism for mixing sugared machine |
| CN108745240A (en) * | 2018-06-06 | 2018-11-06 | 永城职业学院 | A kind of new chemical chemical waste liquid specification recovery processing device |
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Application publication date: 20211022 |
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| RJ01 | Rejection of invention patent application after publication |