CN113521124A - Preparation and process of propolis and kudzu root soft capsule - Google Patents
Preparation and process of propolis and kudzu root soft capsule Download PDFInfo
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- CN113521124A CN113521124A CN202110895965.1A CN202110895965A CN113521124A CN 113521124 A CN113521124 A CN 113521124A CN 202110895965 A CN202110895965 A CN 202110895965A CN 113521124 A CN113521124 A CN 113521124A
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- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims abstract description 21
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- HKEAFJYKMMKDOR-VPRICQMDSA-N puerarin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=CC(C2=O)=C1OC=C2C1=CC=C(O)C=C1 HKEAFJYKMMKDOR-VPRICQMDSA-N 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P39/02—Antidotes
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- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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Abstract
The invention provides a preparation method of propolis kudzu root soft capsule and a process thereof, wherein the process comprises the steps of taking qualified propolis and kudzu root extract for standby; dissolving ethyl p-hydroxybenzoate with ethanol to obtain solution; sequentially adding purified water, sorbitol solution, glycerol, ethyl p-hydroxybenzoate ethanol solution and gelatin into a stainless steel jacketed kettle, stirring and heating, controlling the temperature and the vacuum degree, and performing gelatin melting and degassing for 1-3 hours; accurately weighing propolis and radix Puerariae extract according to formula, adding a little polyethylene glycol, heating to dissolve completely, adding the rest polyethylene glycol 400, mixing completely, placing in a vacuum pan to remove gas and water in the material, and placing the material liquid in a stainless steel barrel; preparing the glue solution in the heat-preserving barrel into a glue skin, filling the prepared content and pressing the content into soft capsules; and packaging according to the packaging specification requirements, finally, correctly counting the number of finished products after each batch of packaging is finished, and timely warehousing to finish the process flow after the finished products are inspected to be qualified.
Description
Technical Field
The invention is applied to the technical field of health-care medicine preparation, and particularly relates to a preparation method and a process of a propolis-radix puerariae soft capsule.
Background
Propolis is "purple gold" and is a natural active substance formed by mixing resin in bee plant buds and secretion thereof, and the main active ingredient of the propolis is a flavonoid compound. The propolis plays a unique biological effect in various aspects of tumor resistance, oxidation resistance, inflammation resistance, immunity improvement and the like, and foreign medical research proves that the propolis has a good repairing effect on chemical liver injury caused by alcohol, medicaments and emergency reaction. Therefore, the propolis product can play a certain role in protecting the liver after long-term drinking for people who drink wine for a long time, are in a working environment with damage to the liver or have chronic liver diseases.
The radix Puerariae is dried root of Pueraria lobata or Pueraria thomsonii of Leguminosae. Sweet and pungent in flavor and mild in nature. Enter spleen and stomach meridians. The functions are as follows: relieving exterior syndrome, expelling pathogenic factors from muscles and skin, invigorating yang, promoting eruption, relieving fever, promoting salivation, relieving restlessness, quenching thirst, and relieving diarrhea. The main treatment is as follows: typhoid fever, tepidity, headache, stiff neck, dysphoria with smothery sensation, diabetes, diarrhea, dysentery, macula impetigo, hypertension, angina pectoris, and deafness. The kudzu root can effectively antagonize liver tissue lipid peroxidation damage caused by alcohol. Experiments also show that the kudzuvine root accelerates the metabolism and excretion of some toxins in the body, thereby reducing the toxic and side effects of the kudzuvine root on the body. The pueraria isoflavone has obvious effect of reducing the content of lipid peroxidation products in blood and brain tissues. Puerarin can relieve liver tissue degeneration and necrosis, relieve pathological change of liver tissue, and protect against acute liver injury
Based on the above, the invention provides a preparation method and a process of the propolis-radix puerariae soft capsule, and aims to prepare a health food which has no peculiar smell, is convenient to take and has an auxiliary protection function on chemical liver injury.
Disclosure of Invention
The invention provides a health food with auxiliary protection function for repairing chemical liver injury by propolis and promoting metabolism and excretion of toxin in vivo by radix puerariae, and further provides a preparation method and a process of the propolis-radix puerariae soft capsule.
The invention adopts the following technical means for solving the technical problems:
a propolis and radix Puerariae soft capsule is prepared from propolis and radix Puerariae extract as main contents, polyethylene glycol 400 as dispersion medium, and gelatin, glycerol, sorbitol, ethyl p-hydroxybenzoate and purified water as soft capsule shell materials, wherein the mass ratio of each component is respectively as follows:
the contents comprise 15-20 parts of propolis, 10-15 parts of kudzu root extract and 400 parts of polyethylene glycol, 65-70 parts of
In the rubber, 35-40 parts of gelatin, 10-13 parts of glycerin, 8-11 parts of sorbitol, 0.01-0.03 part of ethyl p-hydroxybenzoate and 35-40 parts of purified water.
Further, the propolis-radix puerariae soft capsule comprises the following components in parts by mass:
the contents comprise 16 parts of propolis, 12 parts of kudzu root extract, 400 parts of polyethylene glycol, 72 parts of,
The rubber comprises 35 parts of gelatin, 10 parts of glycerol, 8 parts of sorbitol, 0.01 part of ethyl p-hydroxybenzoate and 47 parts of purified water.
The invention also provides a preparation process of the propolis and radix puerariae soft capsule, which is used for preparing the propolis and radix puerariae soft capsule and comprises the following steps:
taking propolis and radix Puerariae extract qualified in inspection for use;
dissolving ethyl p-hydroxybenzoate with ethanol to obtain solution;
and sequentially adding purified water, sorbitol solution, glycerol, ethyl p-hydroxybenzoate ethanol solution and gelatin into a stainless steel jacketed kettle, stirring and heating, controlling the temperature and the vacuum degree, and performing gelatin melting and degassing for 1-3 hours. Degassing the glue solution, storing at 50-65 ℃, and keeping the temperature for 8-12 hours to wait for the next process;
accurately weighing propolis and radix Puerariae extract according to formula, adding a little polyethylene glycol, heating to dissolve completely, adding the rest polyethylene glycol 400, mixing completely, placing in a vacuum pan to remove gas and water in the material, and placing the material liquid in a stainless steel barrel;
and (3) preparing the glue solution in the heat-preserving barrel into a glue skin, filling the prepared content and pressing into soft capsules. Pressing the ring material at normal temperature to obtain soft capsule.
Shaping the pressed capsules for 1-3 hours by using a stainless steel capsule shaping dryer, then pouring the pills into an ethanol pill washing tank for washing the pills, then carrying out shaping and drying for 8-20 hours by using the stainless steel capsule shaping dryer, then selecting special-shaped pills with quality problems, and collecting positive pills to obtain a propolis and radix puerariae soft capsule finished material;
and packaging according to the packaging specification requirements, finally, correctly counting the number of finished products after each batch of packaging is finished, and timely warehousing to finish the process flow after the finished products are inspected to be qualified.
Further, the operation steps of dissolving ethyl p-hydroxybenzoate with ethanol to prepare a solution comprise:
95% ethanol is adopted, and the prepared concentration of the ethyl hydroxybenzoate solution is 20%.
Further, the operation steps of sequentially adding the purified water, the sorbitol solution, the glycerol, the ethyl p-hydroxybenzoate ethanol solution and the gelatin into a stainless steel jacketed kettle for gelatin melting comprise:
heating and stirring are carried out for 1.0-2 hours, the temperature is controlled to be 60-70 ℃, and the vacuum degree is-0.085-0.1 MPa.
Further, the operation steps of accurately weighing the propolis and the kudzu root extract according to the formula, adding a little polyethylene glycol for heating, dissolving and degassing comprise:
the heating and dissolving temperature is as follows: 70-80 ℃;
the gas and water in the materials are removed in a vacuum pan under the condition that the vacuum degree is less than-0.06 MPa.
Further, the step of making the glue solution in the heat-preserving container into the glue skin comprises:
the thickness of the rubber should be about 750mm to 950 mm.
Further, the operation steps of pressing the soft capsule capsules meeting the specification comprise
The environmental temperature of the capsule is controlled at 18-24 deg.C during pressing operation;
the specification of the capsule is as follows: 500 mg/granule, plus-minus deviation 9%
Further, the steps of drying and sizing the pressed capsules, pouring the pills into an ethanol pill washing tank for washing the pills, then sizing and drying the pills by a sizing dryer, selecting special-shaped pills with quality problems, and carrying out sizing, pill washing, drying and pill sorting comprise:
the temperature of the capsule is controlled at 18-24 deg.C when the capsule is dried and shaped by the dryer, the capsule is washed with 95% ethanol, and the drying operation after washing the capsule is carried out at 22-26 deg.C.
Further, the step of packaging according to the packaging specification comprises:
the quantity of finished products in the box is required to be accurate, and the batch number is correct, clear and correct.
The invention provides a preparation process of a propolis and radix puerariae soft capsule, which has the following beneficial effects:
(1) the raw materials of the product are propolis and kudzu root extract. Extracting radix Puerariae extract with ethanol, and dissolving in polyethylene glycol 400 (PEG 400). Therefore, the product selects polyethylene glycol 400 as a diluent. Because PEG400 is liquid, it has wide compatibility with various solvents, it is very good solvent and solubilizer, is used in the liquid preparation extensively, this is mainly because PEG is stable, difficult to deteriorate, the injection containing PEG is very safe, very stable when heated to 150 degrees centigrade;
(2) the capsule shell material is selected, and ethyl p-hydroxybenzoate is used as food additive and has antiseptic effect. The medicine is white, crystalline, and almost odorless powder. Slightly bitter and burning tingle. It is almost insoluble in cold water, and is easily soluble in ethanol, diethyl ether, acetone or propylene glycol. Has strong antifungal effect, can be used as antibacterial antiseptic, and can be widely used in liquid preparation and semisolid preparation, and also can be used for food preservation. The sorbitol solution is colorless, transparent and thick liquid. Sorbitol is one of the sugar alcohols that was first allowed to be used as a food additive in japan, and is used for improving the moisture retention of foods or as a thickener. The liquid polyethylene glycol has water absorption, can transfer water from capsule membrane into the liquid in the capsule, and the polyethylene glycol 400 has hardening effect on capsule membrane gelatin, and can be reduced by adding glycerol and sorbitol.
(3) The soft capsule has the advantages of high bioavailability, good appearance, convenient administration, and easy storage and transportation.
Description of the drawings:
fig. 1 is a schematic flow chart of a process for preparing the soft capsule of kudzuvine root in one embodiment of the invention.
Detailed Description
It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The technical solutions in the embodiments of the present invention will be described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides a propolis kudzu root soft capsule which is prepared by adopting propolis and kudzu root extracts as main contents, polyethylene glycol 400 as a dispersion medium and gelatin, glycerin, sorbitol, ethyl p-hydroxybenzoate and purified water as soft capsule shell materials, wherein the mass ratio of each component is as follows:
the contents comprise 15-20 parts of propolis, 10-15 parts of kudzu root extract and 400 parts of polyethylene glycol, 65-70 parts of
In the rubber, 35-40 parts of gelatin, 10-13 parts of glycerin, 8-11 parts of sorbitol, 0.01-0.03 part of ethyl p-hydroxybenzoate and 35-40 parts of purified water.
Propolis is a natural active substance formed by mixing resin in bee plant sprouts and secretion thereof, and the main active ingredient of the propolis is a flavonoid compound. The propolis plays a unique biological effect in various aspects of tumor resistance, oxidation resistance, inflammation resistance, immunity improvement and the like, and foreign medical research proves that the propolis has a good repairing effect on chemical liver injury caused by alcohol, medicaments and emergency reaction. Therefore, for people who drink wine for a long time, are in a working environment with damage to the liver or have chronic liver diseases, the propolis product can play a certain role in protecting the liver after long-term use, and the propolis product is applied to the technical field of food.
In one embodiment, the propolis-radix puerariae soft capsule comprises the following components in percentage by mass:
the contents comprise 16 parts of propolis, 12 parts of kudzu root extract, 400 parts of polyethylene glycol, 72 parts of,
The rubber comprises 35 parts of gelatin, 10 parts of glycerol, 8 parts of sorbitol, 0.01 part of ethyl p-hydroxybenzoate and 47 parts of purified water.
The invention provides a preparation method of propolis and radix puerariae soft capsules and a process thereof, the preparation method of the propolis and radix puerariae soft capsules adopts a preparation process, and the process comprises the following steps:
s1, taking the qualified propolis and kudzu root extracts for later use;
s2, dissolving ethyl p-hydroxybenzoate with ethanol to obtain a solution for later use;
sequentially adding purified water, sorbitol solution, glycerol, ethyl p-hydroxybenzoate ethanol solution and gelatin into a stainless steel jacketed kettle, stirring and heating, controlling the temperature and the vacuum degree, carrying out gelatin melting and degassing for 1-3 hours, preserving the gelatin solution at 50-65 ℃ after degassing, and keeping the temperature for 8-12 hours for waiting for the next process;
s3, accurately weighing propolis and radix Puerariae extract according to the formula, adding a little polyethylene glycol, heating to dissolve completely, adding the rest polyethylene glycol 400, mixing completely, placing in a vacuum pan to remove gas and water in the material, and placing the material liquid in a stainless steel barrel for use;
s4, preparing the glue solution in the heat-preserving barrel into a glue skin, filling the prepared content and pressing into soft capsules. Pressing soft capsule at normal temperature;
s5, shaping the pressed capsules by a stainless steel capsule shaping dryer for 1-3 hours, then pouring the pills into ethanol for pill washing of a pill washing groove, then carrying out shaping and drying for 8-20 hours by the stainless steel capsule shaping dryer, then selecting special-shaped pills with quality problems, and collecting positive pills to obtain the finished propolis and radix puerariae soft capsules;
and S6, packaging according to the packaging specification requirements, finally, counting the number of finished products correctly after each batch of packaging is finished, and warehousing in time to finish the process flow after the finished products are inspected to be qualified.
In one embodiment, the step of dissolving ethyl paraben with ethanol to form a solution comprises:
95% ethanol is adopted, and the prepared concentration of the ethyl hydroxybenzoate solution is 20%.
In one embodiment, the operation steps of adding purified water, sorbitol solution, glycerol, ethyl p-hydroxybenzoate ethanol solution and gelatin into a stainless steel jacketed kettle in sequence for gelatin melting comprise:
heating and stirring are carried out for 1.0-2 hours, the temperature is controlled to be 60-70 ℃, and the vacuum degree is-0.085-0.1 MPa.
In one embodiment, the steps of accurately weighing propolis and radix Puerariae extract according to the formula, and adding a little polyethylene glycol for heating, dissolving and degassing include:
the heating and dissolving temperature is as follows: 70-80 ℃;
the gas and water in the materials are removed in a vacuum pan under the condition that the vacuum degree is less than-0.06 MPa.
In one embodiment, the step of making the glue solution in the heat preservation barrel into the glue skin comprises the following steps:
the thickness of the rubber should be about 750mm to 950 mm.
In one embodiment, the step of compressing the soft capsule comprises
The environmental temperature of the capsule is controlled at 18-24 deg.C during pressing operation;
the specification of the capsule is as follows: 500 mg/granule, plus-minus deviation 9%
In one embodiment, the steps of drying and shaping the pressed capsules, pouring the pills into an ethanol pill washing tank for washing the pills, shaping and drying the pills by a shaping dryer, selecting special-shaped pills with quality problems, and shaping, washing, drying and picking the pills comprise:
the temperature of the capsule is controlled at 18-24 deg.C when the capsule is dried and shaped by the dryer, the capsule is washed with 95% ethanol, and the drying operation after washing the capsule is carried out at 22-26 deg.C.
In one embodiment, the step of packaging according to the packaging specification comprises:
the quantity of finished products in the box is required to be accurate, and the batch number is correct, clear and correct.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (10)
1. The propolis-kudzu root soft capsule is characterized by being prepared by adopting propolis and kudzu root extracts as main contents, polyethylene glycol 400 as a dispersion medium and gelatin, glycerin, sorbitol, ethyl p-hydroxybenzoate and purified water as soft capsule shell materials, wherein the mass ratio of each component is as follows:
the contents comprise 15-20 parts of propolis, 10-15 parts of kudzu root extract and 400 parts of polyethylene glycol, 65-70 parts of
In the rubber, 35-40 parts of gelatin, 10-13 parts of glycerin, 8-11 parts of sorbitol, 0.01-0.03 part of ethyl p-hydroxybenzoate and 35-40 parts of purified water.
2. The propolis-kudzu root soft capsule according to claim 1, which is characterized in that the propolis-kudzu root soft capsule comprises the following components in parts by mass:
the contents comprise 16 parts of propolis, 12 parts of kudzu root extract, 400 parts of polyethylene glycol, 72 parts of,
The rubber comprises 35 parts of gelatin, 10 parts of glycerol, 8 parts of sorbitol, 0.01 part of ethyl p-hydroxybenzoate and 47 parts of purified water.
3. A preparation process of the propolis kudzu root soft capsule is characterized in that the preparation process is adopted to prepare the propolis kudzu root soft capsule of claim 1 or 2, and the process comprises the following steps:
taking propolis and radix Puerariae extract qualified in inspection for use;
dissolving ethyl p-hydroxybenzoate with ethanol to obtain solution;
sequentially adding purified water, sorbitol solution, glycerol, ethyl p-hydroxybenzoate ethanol solution and gelatin into a stainless steel jacketed kettle, stirring and heating, controlling the temperature and the vacuum degree, carrying out gelatin melting and degassing for 1-3 hours, preserving the gelatin solution at 50-65 ℃ after degassing, and keeping the temperature for 8-12 hours for waiting for the next process;
accurately weighing propolis and radix Puerariae extract according to formula, adding a little polyethylene glycol, heating to dissolve completely, adding the rest polyethylene glycol 400, mixing completely, placing in a vacuum pan to remove gas and water in the material, and placing the material liquid in a stainless steel barrel;
making the glue solution in the heat-insulating barrel into a glue skin, filling the prepared content and pressing the content into soft capsules,
pressing soft capsule at normal temperature;
shaping the pressed capsules for 1-3 hours by using a stainless steel capsule shaping dryer, then pouring the pills into an ethanol pill washing tank for washing the pills, then carrying out shaping and drying for 8-20 hours by using the stainless steel capsule shaping dryer, then selecting special-shaped pills with quality problems, and collecting positive pills to obtain a propolis and radix puerariae soft capsule finished material;
and packaging according to the packaging specification requirements, finally, correctly counting the number of finished products after each batch of packaging is finished, and timely warehousing to finish the process flow after the finished products are inspected to be qualified.
4. The process for preparing the soft capsule of pueraria lobata of claim 3, wherein the step of dissolving ethyl paraben in ethanol to form a solution comprises:
95% ethanol is adopted, and the prepared concentration of the ethyl hydroxybenzoate solution is 20%.
5. The process for preparing the soft capsule of kudzuvine root according to claim 3, wherein the step of sequentially adding purified water, sorbitol solution, glycerol, ethyl p-hydroxybenzoate solution and gelatin into a stainless steel jacketed kettle for gelatin melting comprises:
heating and stirring are carried out for 1.0-2 hours, the temperature is controlled to be 60-70 ℃, and the vacuum degree is-0.085-0.1 MPa.
6. The process for preparing the soft capsule of glue kudzu root according to claim 3, wherein the steps of accurately weighing the propolis and the kudzu root extract according to the formula, and adding a little polyethylene glycol for heating, dissolving and degassing comprise:
the heating and dissolving temperature is as follows: 70-80 ℃;
the gas and water in the materials are removed in a vacuum pan under the condition that the vacuum degree is less than-0.06 MPa.
7. The process for preparing the soft capsule of kudzuvine root according to claim 3, wherein the step of preparing the glue solution in the heat-preserving container into the glue skin comprises the following steps:
the thickness of the rubber should be about 750mm to 950 mm.
8. The process for preparing the soft capsule of kudzuvine root according to claim 3, wherein the step of pressing the soft capsule according to the specification comprises:
the environmental temperature of the capsule is controlled at 18-24 deg.C during pressing operation;
the specification of the capsule is as follows: 500 mg/granule, with a plus-minus deviation of 9%.
9. The process for preparing the soft capsule of kudzuvine root according to claim 3, wherein the steps of drying and sizing the pressed capsule, pouring the pellet into an ethanol pellet washing tank for washing the pellet, shaping and drying the pellet by a shaping dryer, selecting the abnormal-shaped pellet with quality problems, shaping, washing, drying and sorting the abnormal-shaped pellet comprise:
the temperature of the capsule is controlled at 18-24 deg.C when the capsule is dried and shaped by the dryer, the capsule is washed with 95% ethanol, and the drying operation after washing the capsule is carried out at 22-26 deg.C.
10. The process for preparing the soft capsule of kudzuvine root according to claim 3, wherein the step of packaging according to the packaging specification comprises:
the quantity of finished products in the box is required to be accurate, and the batch number is correct, clear and correct.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110895965.1A CN113521124A (en) | 2021-08-05 | 2021-08-05 | Preparation and process of propolis and kudzu root soft capsule |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110895965.1A CN113521124A (en) | 2021-08-05 | 2021-08-05 | Preparation and process of propolis and kudzu root soft capsule |
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| CN106491653A (en) * | 2016-11-02 | 2017-03-15 | 深圳市荣格保健品有限公司 | A kind of bee glue soft capsule and preparation method thereof |
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Application publication date: 20211022 |