CN113476549A - External medicine for treating pruritus, scald, trauma and mosquito bite - Google Patents

External medicine for treating pruritus, scald, trauma and mosquito bite Download PDF

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CN113476549A
CN113476549A CN202110906201.8A CN202110906201A CN113476549A CN 113476549 A CN113476549 A CN 113476549A CN 202110906201 A CN202110906201 A CN 202110906201A CN 113476549 A CN113476549 A CN 113476549A
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alcohol solution
scald
trauma
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陈绪国
王细姣
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/04Antipruritics
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
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    • A61P31/10Antimycotics
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The invention discloses an external medicine for treating pruritus, scald, trauma and mosquito bite, which comprises 0.5-1.5% of folium artemisiae argyi extract, 2.5-4.5% of radix sophorae flavescentis extract, 2-4% of radix zanthoxyli extract, 0.5-2.5% of garlic extract, 0.5-2.5% of cynanchum paniculatum extract and 85-94% of alcohol solution by mass percentage, wherein the concentration of the alcohol solution is 30-40%. The Chinese medicinal composition is easy to prepare, can clear away plague and toxic materials, eliminate scytitis, promote blood circulation of skin, improve skin immunity, has a strong bactericidal effect on the skin, has a good caring effect on the skin, has a bactericidal rate of more than 98% on escherichia coli, staphylococcus aureus and candida albicans, can treat pruritus, eczema, scald and trauma, and has the effects of relieving swelling and pain, diminishing inflammation, resisting viruses, resisting allergy and the like.

Description

External medicine for treating pruritus, scald, trauma and mosquito bite
Technical Field
The invention relates to the technical field of antibacterial liquid, and particularly relates to an external medicine for treating pruritus, scald, trauma and mosquito bite.
Background
Coli (e.coli) is a representative of Escherichia (Escherichia). Generally, the medicine is not pathogenic, and can cause parenteral infection under certain conditions due to the inhabitant bacteria in human and animal intestinal tracts. Some serotype strains are highly pathogenic, causing diarrhea, collectively referred to as pathogenic E.coli. The bacteria has stronger heat resistance than other intestinal bacilli, and partial bacteria still survive after heating at 55 ℃ for 60 minutes or 60 ℃ for 15 minutes. Can survive in water of nature for several weeks to months, and can survive in feces with lower temperature for a longer time. Bile salt and brilliant green have inhibiting effect on Escherichia coli. Is sensitive to sulfonamides, streptomycin, chloramphenicol and the like, but is easily resistant, and is obtained by transferring a plasmid with an R factor.
Staphylococcus aureus (Staphylococcus aureus) is an important pathogenic bacterium in human beings, belongs to the genus Staphylococcus (Staphylococcus), is called as a "mesophilic bacterium", is a representative of gram-positive bacteria, and can cause many serious infections and food poisoning.
Candida Albicans (Monilia Albicans or Candida Albicans), a fungus, is usually present in the mouth, upper respiratory tract, intestinal tract and vagina of normal people, is generally small in number in normal organisms, does not cause diseases, and is proliferated in large quantities and invades cells to change the growth form (blastomycelial phase) to cause diseases when the immune function or general defense capacity of the organisms is reduced or the mutual restriction of normal flora is disordered.
The sterilization effect of the skin antibacterial liquid is taken as one of important indexes for skin sterilization, the existing market shows an external medicament for treating pruritus, scald, trauma and mosquito bite, which can kill escherichia coli and staphylococcus aureus, but the external medicament has poor sterilization effect on the escherichia coli, the staphylococcus aureus and candida albicans, and can not well protect the skin.
Therefore, there is a need for improvements in the prior art to avoid the disadvantages of the prior art.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide an external medicine which is easy to prepare and has good bactericidal effect and is used for treating pruritus, scald, trauma and mosquito bite.
The invention is realized by the following technical scheme:
an external medicine for treating pruritus, scald, trauma and mosquito bite comprises 0.5-1.5% of folium artemisiae argyi extract, 2.5-4.5% of radix sophorae flavescentis extract, 2-4% of radix zanthoxyli extract, 0.5-2.5% of garlic extract, 0.5-2.5% of cynanchum paniculatum extract and 85-94% of alcohol solution by mass, wherein the concentration of the alcohol solution is 30-40%.
Further, the traditional Chinese medicine composition comprises 0.6-1.4% of folium artemisiae argyi extract, 2.8-4.2% of radix sophorae flavescentis extract, 2.2-3.8% of radix zanthoxyli extract, 0.8-2.4% of garlic extract, 0.6-2.4% of paniculate swallowwort root extract and 86-93% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 32-38%.
Further, the traditional Chinese medicine composition comprises 0.8-1.2% of folium artemisiae argyi extract, 3.2-4% of radix sophorae flavescentis extract, 2.6-3.6% of radix zanthoxyli extract, 1.2-2.2% of garlic extract, 1.2-2.2% of paniculate swallowwort root extract and 87-92% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 33-37%.
Further, the traditional Chinese medicine composition comprises 0.9-1.1% of folium artemisiae argyi extract, 3-3.7% of radix sophorae flavescentis extract, 2.5-3.2% of radix zanthoxyli extract, 1.2-2.4% of garlic extract, 1.4-1.6% of paniculate swallowwort root extract and 88-91% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 34-36%.
Further, the traditional Chinese medicine composition comprises 1.2% of folium artemisiae argyi extract, 3.8% of radix sophorae flavescentis extract, 3.5% of radix zanthoxyli extract, 1% of garlic extract, 2% of paniculate swallowwort root extract and 88.5% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 36%.
Further, the traditional Chinese medicine composition comprises 1% of folium artemisiae argyi extract, 3.5% of radix sophorae flavescentis extract, 3% of radix zanthoxyli extract, 1.5% of garlic extract, 1.5% of paniculate swallowwort root extract and 89.5% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 35%.
Compared with the prior art, the external medicine for treating pruritus, scald, trauma and mosquito bite is easy to prepare by dissolving the folium artemisiae argyi extract, the radix sophorae flavescentis extract, the radix zanthoxyli extract, the garlic extract and the radix cynanchi paniculatae extract in an alcohol solution, the folium artemisiae argyi extract can dispel cold to promote blood circulation of skin and improve immunity of skin, the radix sophorae flavescentis extract has whitening, anti-inflammatory, anti-acne and antibacterial effects on skin, the radix zanthoxyli extract can dredge collaterals, expel wind and activate blood, the garlic extract has antipyretic, detoxifying, blood circulation promoting and stasis removing effects on skin, the radix cynanchi paniculati extract can expel wind and remove dampness of skin, the folium artemisiae argyi extract, the radix sophorae flavescentis extract, the radix zanthoxyli extract, the garlic extract and the radix cynanchi paniculatae extract are combined, antipyretic and detoxifcation are achieved, inflammation of skin is eliminated, blood circulation of skin is promoted, and immunity of skin is improved, has good effect of protecting skin, strong bactericidal effect on skin, and high bactericidal rate of more than 98% on escherichia coli, staphylococcus aureus and candida albicans, can treat pruritus, eczema, scald and trauma, and has the effects of relieving swelling and pain, diminishing inflammation, resisting virus, resisting allergy and the like.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
An external medicine for treating pruritus, scald, trauma and mosquito bite comprises 0.5-1.5% of folium artemisiae argyi extract, 2.5-4.5% of radix sophorae flavescentis extract, 2-4% of radix zanthoxyli extract, 0.5-2.5% of garlic extract, 0.5-2.5% of cynanchum paniculatum extract and 85-94% of alcohol solution by mass percent, wherein the concentration of the alcohol solution is 30-40%
Further, the traditional Chinese medicine composition comprises 0.6-1.4% of folium artemisiae argyi extract, 2.8-4.2% of radix sophorae flavescentis extract, 2.2-3.8% of radix zanthoxyli extract, 0.8-2.4% of garlic extract, 0.6-2.4% of paniculate swallowwort root extract and 86-93% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 32-38%.
Further, the traditional Chinese medicine composition comprises 0.8-1.2% of folium artemisiae argyi extract, 3.2-4% of radix sophorae flavescentis extract, 2.6-3.6% of radix zanthoxyli extract, 1.2-2.2% of garlic extract, 1.2-2.2% of paniculate swallowwort root extract and 87-92% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 33-37%.
Further, the traditional Chinese medicine composition comprises 0.9-1.1% of folium artemisiae argyi extract, 3-3.7% of radix sophorae flavescentis extract, 2.5-3.2% of radix zanthoxyli extract, 1.2-2.4% of garlic extract, 1.4-1.6% of paniculate swallowwort root extract and 88-91% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 34-36%.
Further, the traditional Chinese medicine composition comprises 1.2% of folium artemisiae argyi extract, 3.8% of radix sophorae flavescentis extract, 3.5% of radix zanthoxyli extract, 1% of garlic extract, 2% of paniculate swallowwort root extract and 88.5% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 36%.
Further, the traditional Chinese medicine composition comprises 1% of folium artemisiae argyi extract, 3.5% of radix sophorae flavescentis extract, 3% of radix zanthoxyli extract, 1.5% of garlic extract, 1.5% of paniculate swallowwort root extract and 89.5% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 35%.
The folium Artemisiae Argyi extract has effects of warming channels, stopping bleeding, dispelling cold, relieving pain, eliminating dampness, and relieving itching. It can be used for treating hematemesis, epistaxis, hemoptysis, hematochezia, metrorrhagia, gestational hemorrhage, menoxenia, dysmenorrhea, threatened abortion, psychroalgia of heart and abdomen, diarrhea, dysentery, cholera, spasm of muscle, leukorrhagia, eczema, scabies, tinea, hemorrhoid, and carbuncle.
The radix Sophorae Flavescentis extract has skin whitening, antiinflammatory, acne resisting, and antibacterial effects. The main effective components are matrine (matrine), oxymatrine (oxymatrine), oxymatrine (sodium-anol), N-methylcardealine (N-methylcytisine), anageine (anagyrine), bap-ifinoline (bap-ifinoline), dehydromatrine (sophocarpine), d-isomatrine (d-isomatrine), and kuraridine (kurarid-in). Norkurarinone, kurarinol, neo-kurarinol, norkurarinol, isokurarinone, formononetin.
The radix zanthoxyli extract has the main efficacy, and has the functions of dispelling wind, dredging collaterals, reducing swelling, relieving pain, promoting qi circulation, relieving pain, promoting blood circulation, removing blood stasis, dispelling wind and dredging collaterals. The main effective component is nitidine chloride.
The garlic extract has the functions of clearing plague, detoxifying, activating blood and dissolving stasis, is a typical antibiotic and a bactericide, has an immune function on irritant substances, has a certain curative effect on asthma, cold, diabetes and vaginal infection, has an antiviral effect, can reduce blood fat, blood pressure and blood sugar, and can also resist platelet aggregation, and the main components are as follows:
1. the sulfur-containing compounds alliin and cycloalliin have the effects of resisting bacteria, hepatotoxicity, aging and the like, and can enhance the activity of plasminogen.
2. The garlic volatile oil (also called garlic essential oil) comprises allicin (allicin), Methyl Allylated Trithione (MATS), ajoene (ajoene) and the like, wherein the allicin (allicin) is a main component of the garlic volatile oil and has strong antibacterial activity, the Methyl Allylated Trithione (MATS) can inhibit platelet aggregation, and the ajoene (ajoene) is a mild antithrombotic agent.
3. Allicin has effects of activating cell, promoting energy production, increasing antibacterial and antiviral ability, accelerating metabolism, and relieving fatigue. Allicin can combine with other substances (saccharides, lipids, proteins, etc.) to produce compound effect, and also has effects of dilating blood vessel and improving blood circulation.
The cynanchum paniculatum extract is a medicine for dispelling wind and dampness, and is mainly used for dispelling wind and eliminating dampness, and relieving pain and itching. It can also be used for treating rheumatism, gastralgia, abdominal distention, toothache, lumbago, traumatic injury, urticaria, and eczema.
Compared with the prior art, the external medicine for treating pruritus, scald, trauma and mosquito bite is easy to prepare by dissolving the folium artemisiae argyi extract, the radix sophorae flavescentis extract, the radix zanthoxyli extract, the garlic extract and the radix cynanchi paniculatae extract in an alcohol solution, the folium artemisiae argyi extract can dispel cold to promote blood circulation of skin and improve immunity of skin, the radix sophorae flavescentis extract has whitening, anti-inflammatory, anti-acne and antibacterial effects on skin, the radix zanthoxyli extract can dredge collaterals, expel wind and activate blood, the garlic extract has antipyretic, detoxifying, blood circulation promoting and stasis removing effects on skin, the radix cynanchi paniculati extract can expel wind and remove dampness of skin, the folium artemisiae argyi extract, the radix sophorae flavescentis extract, the radix zanthoxyli extract, the garlic extract and the radix cynanchi paniculatae extract are combined, antipyretic and detoxifcation are achieved, inflammation of skin is eliminated, blood circulation of skin is promoted, and immunity of skin is improved, has good effect of protecting skin, strong bactericidal effect on skin, and high bactericidal rate of more than 98% on escherichia coli, staphylococcus aureus and candida albicans, can treat pruritus, eczema, scald and trauma, and has the effects of relieving swelling and pain, diminishing inflammation, resisting virus, resisting allergy and the like.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (6)

1. An external medicine for treating pruritus, scald, trauma and mosquito bite is characterized in that: comprises 0.5 to 1.5 percent of folium artemisiae argyi extract, 2.5 to 4.5 percent of radix sophorae flavescentis extract, 2 to 4 percent of radix zanthoxyli extract, 0.5 to 2.5 percent of garlic extract, 0.5 to 2.5 percent of cynanchum paniculatum extract and 85 to 94 percent of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 30 to 40 percent.
2. The external medicine for treating pruritus, scald, trauma and mosquito bite according to claim 1, which is characterized in that: comprises 0.6 to 1.4 percent of folium artemisiae argyi extract, 2.8 to 4.2 percent of radix sophorae flavescentis extract, 2.2 to 3.8 percent of radix zanthoxyli extract, 0.8 to 2.4 percent of garlic extract, 0.6 to 2.4 percent of cynanchum paniculatum extract and 86 to 93 percent of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 32 to 38 percent.
3. The external medicine for treating pruritus, scald, trauma and mosquito bite according to claim 1, which is characterized in that: comprises 0.8 to 1.2 percent of folium artemisiae argyi extract, 3.2 to 4 percent of radix sophorae flavescentis extract, 2.6 to 3.6 percent of radix zanthoxyli extract, 1.2 to 2.2 percent of garlic extract, 1.2 to 2.2 percent of cynanchum paniculatum extract and 87 to 92 percent of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 33 to 37 percent.
4. The external medicine for treating pruritus, scald, trauma and mosquito bite according to claim 1, which is characterized in that: comprises 0.9 to 1.1 percent of folium artemisiae argyi extract, 3 to 3.7 percent of radix sophorae flavescentis extract, 2.5 to 3.2 percent of radix zanthoxyli extract, 1.2 to 2.4 percent of garlic extract, 1.4 to 1.6 percent of cynanchum paniculatum extract and 88 to 91 percent of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 34 to 36 percent.
5. The external medicine for treating pruritus, scald, trauma and mosquito bite according to claim 1, which is characterized in that: the traditional Chinese medicine composition comprises 1.2% of folium artemisiae argyi extract, 3.8% of radix sophorae flavescentis extract, 3.5% of radix zanthoxyli extract, 1% of garlic extract, 2% of paniculate swallowwort root extract and 88.5% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 36%.
6. The external medicine for treating pruritus, scald, trauma and mosquito bite according to claim 1, which is characterized in that: comprises 1% of folium artemisiae argyi extract, 3.5% of radix sophorae flavescentis extract, 3% of radix zanthoxyli extract, 1.5% of garlic extract, 1.5% of paniculate swallowwort root extract and 89.5% of alcohol solution according to mass percentage, wherein the concentration of the alcohol solution is 35%.
CN202110906201.8A 2021-08-09 2021-08-09 External medicine for treating pruritus, scald, trauma and mosquito bite Pending CN113476549A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1086724A (en) * 1993-08-04 1994-05-18 李社伦 Atomized pudendal cleaning liquid
CN101940776A (en) * 2010-09-13 2011-01-12 张国瑞 Chrysopelea ornata itching relieving liquid
CN104474028A (en) * 2014-12-03 2015-04-01 莫兆钦 Unguent for treating cutaneous pruritus and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1086724A (en) * 1993-08-04 1994-05-18 李社伦 Atomized pudendal cleaning liquid
CN101940776A (en) * 2010-09-13 2011-01-12 张国瑞 Chrysopelea ornata itching relieving liquid
CN104474028A (en) * 2014-12-03 2015-04-01 莫兆钦 Unguent for treating cutaneous pruritus and preparation method thereof

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Application publication date: 20211008