CN113457759A

CN113457759A - Ice bath box for molecular diagnosis laboratory

Info

Publication number: CN113457759A
Application number: CN202110662134.XA
Authority: CN
Inventors: 黄怀; 黎梅连
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-06-15
Filing date: 2021-06-15
Publication date: 2021-10-01

Abstract

The invention discloses an ice bath box for a molecular diagnosis laboratory, which comprises a box body, a damping rotating shaft, a box cover, a partition plate, a through hole, a water draining sleeve, a cold water layer, a moving assembly, a reaction tube and a refrigerator, wherein the damping rotating shaft is arranged on the side surface of the box body, the box cover is connected with the damping rotating shaft, the partition plate is connected on the inner side wall of the box body, the through hole is uniformly formed in the partition plate, the water draining sleeve is uniformly arranged on the partition plate and arranged in the through hole, the cold water layer is arranged at the lower end in the box body and arranged below the partition plate, one end of the moving assembly is arranged below the box cover and the other end of the moving assembly is arranged in the box body, the reaction tube penetrates through the water draining sleeve and the moving plate assembly, and the refrigerator is arranged below the partition plate and arranged in the cold water layer. The invention belongs to the technical field of molecular diagnosis devices, and particularly relates to an ice bath box for a molecular diagnosis laboratory.

Description

Ice bath box for molecular diagnosis laboratory

Technical Field

The invention belongs to the technical field of molecular diagnosis devices, and particularly relates to an ice bath box for a molecular diagnosis laboratory.

Background

Molecular diagnosis refers to a technique for diagnosing by detecting the change of the structure or expression level of genetic material in a patient body by applying a molecular biological method, in the molecular diagnosis nucleic acid molecular hybridization, in order to maintain the single-stranded structure of nucleic acid, an ice-water bath is required immediately after the nucleic acid is denatured, at present, a container which is mostly prepared by a laboratory is placed in a refrigerator overnight, water is added after ice making to form the ice-water bath, and then the ice-water bath is inserted into a 0.2ml PCR reaction tube. The ice bath box on the market has no limit structure, ice water is easy to shake and leaks to jack up the reaction tube, and the sample tube cannot be completely immersed in ice water bath, so that the PCR amplification product is easy to recover, and the maintenance of a nucleic acid single-chain structure cannot be guaranteed.

Disclosure of Invention

In order to solve the problems, the invention provides the ice bath box for the molecular diagnosis laboratory, which has the advantages that the reaction tube is taken out of the cold water layer through the movable plate when the box cover is opened through the movable assembly, so that samples can be stored and the reaction condition can be observed conveniently, and meanwhile, the reaction tube is more stable and is favorable for reaction.

In order to realize the functions, the technical scheme adopted by the invention is as follows: the utility model provides a molecular diagnosis laboratory is with ice bath box, includes box body, damping pivot, lid, baffle, through-hole, waterlogging caused by excessive rainfall cover, cold water layer, removal subassembly, reaction tube and refrigerator, the damping pivot is located on the box body side, the lid is connected in the damping pivot, the baffle is connected on the inside wall of box body, the through-hole evenly locates on the baffle, the waterlogging caused by excessive rainfall cover evenly locates on the baffle and in locating the through-hole, the cold water layer is located the box body lower extreme and is located under the baffle, removal subassembly one end is located under the lid and the other end is located in the box body, the reaction tube runs through in waterlogging caused by excessive rainfall cover and removal subassembly, the refrigerator is located under the baffle and is located in the cold water layer; the moving assembly comprises connecting blocks, sliding grooves, a moving plate, inserting holes, grooves, rotating rods and connecting rods, the connecting blocks are arranged at one end, close to the damping rotating shaft, of the box cover, the connecting blocks are symmetrically arranged in two groups by taking the central line of the box body as a symmetry axis, the sliding grooves are symmetrically arranged at the upper end of the inner side wall of the box body, two ends of the moving plate can be movably arranged in the sliding grooves and are arranged above the partition plate, the inserting holes are uniformly arranged on the moving plate and correspond to the through holes, the grooves are symmetrically arranged on the moving plate, the rotating rods can be rotatably arranged on the moving plate and can be rotatably arranged in the grooves, one end of each connecting rod is sleeved on the corresponding rotating rod, the other end of each connecting rod is hinged to the corresponding connecting block, the box cover is opened, the moving plate is pulled by the corresponding connecting blocks and the corresponding connecting rods to the moving plates to move upwards along the sliding grooves in the rotating process, and the moving plates drive the reaction tubes to move upwards in the moving process of moving upwards, the reaction tube is convenient to take out of a cold water layer and is convenient to store samples or observe the reaction condition.

Further, the anticreep board has been cup jointed to the reaction tube upper end, the size of anticreep board is greater than the size of through-hole, prevents that the reaction tube from droing at the in-process that rises along with the movable plate.

Furthermore, a lock ring is arranged on the side face, away from the damping rotating shaft, of the box cover, a lock catch is arranged at the upper end of the side face, away from the damping rotating shaft, of the box body, and the box cover is opened or locked through the lock ring and the lock catch.

Furthermore, a handle is arranged on the box cover, so that the box cover can be conveniently opened and the ice bath box can be conveniently carried.

Furthermore, the reaction tube is detachably provided with a plug, so that the sample is prevented from being spilled out of the reaction tube in the carrying process.

Furthermore, the bottom of the counter weight is arranged below the reaction tube, so that the reaction tube is prevented from being jacked up by ice water shaking, and the reaction tube is ensured to be always positioned in the ice water layer.

The invention adopts the structure to obtain the following beneficial effects: the invention provides an ice bath box for a molecular diagnosis laboratory, which is characterized in that a box cover is opened, a moving plate is pulled by the box cover to move upwards along a sliding groove through a connecting block and a connecting rod in the rotating process, the moving plate drives a reaction tube to move upwards in the upward movement process, the reaction tube is convenient to take out a cold water layer and store a sample or observe the reaction condition, an anti-falling plate is sleeved at the upper end of the reaction tube, the size of the anti-falling plate is larger than that of a through hole, the reaction tube is prevented from falling off in the ascending process along with the moving plate, the box cover is opened or locked through a locking ring and a locking buckle, a block is detachably arranged on the reaction tube, the sample is prevented from spilling out of the reaction tube in the carrying process, a counterweight bottom is arranged below the reaction tube, the reaction tube is prevented from being jacked up due to ice water shaking, and the reaction tube is ensured to be always positioned in the ice water layer.

Drawings

FIG. 1 is a schematic diagram of the overall structure of an ice bath box for a molecular diagnosis laboratory according to the present invention;

FIG. 2 is a structural diagram of a moving plate, a groove and a rotating rod in the ice bath box for the molecular diagnosis laboratory according to the present invention.

The device comprises a box body 1, a box body 2, a damping rotating shaft 3, a box cover 4, a partition plate 5, a through hole 6, a water draining sleeve 7, a cold water layer 8, a moving assembly 9, a reaction tube 10, a refrigerator 11, a connecting block 12, a sliding groove 13, a moving plate 14, a jack 15, a groove 16, a rotating rod 17, a connecting rod 18, an anti-dropping plate 19, a locking ring 20, a lock catch 21, a handle 22, a plug 23 and a counterweight bottom.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. The present invention will be described in further detail with reference to the accompanying drawings.

As shown in fig. 1-2, the ice bath box for molecular diagnosis laboratory of the present invention comprises a box body 1, a damping rotating shaft 2, a box cover 3, a partition plate 4, through holes 5, a draining sleeve 6, a cold water layer 7, a moving assembly 8, a reaction tube 9 and a refrigerator 10, wherein the damping rotating shaft 2 is arranged on the side surface of the box body 1, the box cover 3 is connected to the damping rotating shaft 2, the partition plate 4 is connected to the inner side wall of the box body 1, the through holes 5 are uniformly arranged on the partition plate 4, the draining sleeve 6 is uniformly arranged on the partition plate 4 and arranged in the through holes 5, the cold water layer 7 is arranged at the lower end in the box body 1 and arranged below the partition plate 4, one end of the moving assembly 8 is arranged below the box cover 3 and the other end is arranged in the box body 1, the reaction tube 9 penetrates through the components of the draining sleeve 6 and the moving plate 13, and the refrigerator 10 is arranged below the partition plate 4 and arranged in the cold water layer 7; remove subassembly 8 includes connecting block 11, spout 12, movable plate 13, jack 14, recess 15, bull stick 16 and connecting rod 17, connecting block 11 locates the lid 3 down and is close to the one end of damping pivot 2, connecting block 11 uses the central line of box body 1 to be equipped with two sets ofly as symmetry axis symmetry, 1 inside wall upper end of box body is located to spout 12 symmetry, movable locating in spout 12 and locating 4 tops of baffle in the both ends of movable plate 13, jack 14 evenly locate on the movable plate 13 and the position corresponding with through-hole 5, recess 15 symmetry is located on the movable plate 13, bull stick 16 is rotatable to be located on the movable plate 13 and rotatable locate in recess 15, connecting rod 17 one end cup joints on bull stick 16 and the other end articulates in connecting block 11.

The upper end of the reaction tube 9 is sleeved with an anti-falling plate 18, and the size of the anti-falling plate 18 is larger than that of the through hole 5.

A lock ring 19 is arranged on the side surface of the box cover 3 far away from the damping rotating shaft 2, and a lock catch 20 is arranged at the upper end of the side surface of the box body 1 far away from the damping rotating shaft 2.

The box cover 3 is provided with a handle 21.

The reaction tube 9 is detachably provided with a plug 22.

A counterweight bottom 23 is arranged below the reaction tube 9.

During the specific use, when the sample is put into, open lid 3 through the handle, lid 3 pulls the movable plate 13 through connecting block 11 and connecting rod 17 and upwards moves along spout 12 at pivoted in-process, movable plate 13 drives reaction tube 9 in the in-process of upwards moving, makes reaction tube 9 break away from cold water layer 7, in addition the in-process of reaction tube 9 upwards moving is driped the water in the outside of reaction tube 9 through waterlogging caused by excessive rainfall cover 6, put into reaction tube 9 with the sample, cover and block up 22, close lid 3, reaction tube 9 descends to cold water layer 7 along with movable plate 13 and carries out the ice bath, lock lid 3 dead through lock ring 19 and hasp 20, portable.

The present invention and its embodiments have been described above, and the description is not intended to be limiting, and the drawings are only one embodiment of the present invention, and the actual structure is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims

1. The utility model provides a molecular diagnosis laboratory is with ice bath box and is put which characterized in that: the box comprises a box body, a damping rotating shaft, a box cover, a partition plate, a through hole, a draining sleeve, a cold water layer, a moving assembly, a reaction tube and a refrigerator, wherein the damping rotating shaft is arranged on the side face of the box body; the movable assembly comprises a connecting block, a sliding groove, a movable plate, jacks, grooves, rotating rods and connecting rods, the connecting block is arranged at one end, close to the damping rotating shaft, of the box cover, the connecting block is arranged at the upper end of the inner side wall of the box body by taking the central line of the box body as symmetry axis symmetry, the upper end of the inner side wall of the box body is arranged at the sliding groove, the two ends of the movable plate can be movably arranged in the sliding groove and are arranged above the partition plate, the jacks are uniformly arranged on the movable plate, the positions of the jacks correspond to the through holes, the grooves are symmetrically arranged on the movable plate, the rotating rods can be rotatably arranged on the movable plate and can be rotatably arranged in the grooves, and one ends of the connecting rods are sleeved on the rotating rods, and the other ends of the connecting rods are hinged to the connecting block.

2. The ice bath box device for molecular diagnosis laboratory according to claim 1, wherein: the anti-disengaging board has been cup jointed to the reaction tube upper end, the size of anti-disengaging board is greater than the size of through-hole.

3. The ice bath box device for molecular diagnosis laboratory according to claim 2, characterized in that: the side of the box cover, which is far away from the damping rotating shaft, is provided with a locking ring, and the upper end of the side of the box body, which is far away from the damping rotating shaft, is provided with a lock catch.

4. The ice bath box device for molecular diagnosis laboratory according to claim 3, characterized in that: the box cover is provided with a handle.

5. The ice bath box device for molecular diagnosis laboratory according to claim 4, wherein: the reaction tube is detachably provided with a plug.

6. The ice bath box device for molecular diagnosis laboratory according to claim 5, wherein: and a counterweight bottom is arranged below the reaction tube.