CN211999748U - Geometric focusing ultrasonic wave breaking equipment based on biological sample treatment - Google Patents

Geometric focusing ultrasonic wave breaking equipment based on biological sample treatment Download PDF

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Publication number
CN211999748U
CN211999748U CN202020589220.3U CN202020589220U CN211999748U CN 211999748 U CN211999748 U CN 211999748U CN 202020589220 U CN202020589220 U CN 202020589220U CN 211999748 U CN211999748 U CN 211999748U
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water
biological sample
transducer
geometric
water tank
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康炎
彭民伟
冯赫天
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Shenzhen Dayuan Chenguang Technology Co ltd
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Shenzhen Dayuan Chenguang Technology Co ltd
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Abstract

The utility model relates to an supersound technical field is applied to biological sample with the ultrasonic wave and handles, concretely relates to equipment is broken to geometry focus ultrasonic wave based on biological sample handles. The ultrasonic transducer assembly comprises a transducer, wherein the transducer comprises an arc-shaped concave emitting surface; the sample placing platform comprises a shearing tube for placing a biological sample, and the shearing tube is arranged at the focusing center of the concave emitting surface. The utility model discloses a contactless supersound breaks the mode, and the cross contamination problem of avoiding the sample that can be fine is solved because the measuring result deviation that cross contamination leads to from the source. Set up curved indent transmitting surface on the transducer, the focus center of transducer is the centre of sphere of indent transmitting surface promptly, adopts the principle of geometry focus supersound like this, and the accuracy of focus is better, so sets up the gathering that makes the ultrasonic wave more accurate and controllable, has reduced the error of breaking the result for measuring result is more accurate.

Description

Geometric focusing ultrasonic wave breaking equipment based on biological sample treatment
Technical Field
The utility model relates to an supersound technical field is applied to biological sample with the ultrasonic wave and handles, concretely relates to equipment is broken to geometry focus ultrasonic wave based on biological sample handles.
Background
The core element of the ultrasonic transducer assembly is an ultrasonic transducer, which is a device capable of converting electricity used in daily life into mechanical energy, and is an energy conversion device. The application of ultrasonic focusing to disrupt fragmentation is an extremely delicate technique.
For related applications such as NGS ("Next-generation" sequencing technology) gene sequencing, cell disruption, DNA, and RNA extraction are tasks that must be performed. At present, ultrasound and enzymatic methods are mainly used in this respect, with ultrasound being further subdivided into contact and contactless methods. For a contact type ultrasonic interruption mode, the problem of cross contamination of samples is easily caused, and deviation is caused to a final detection result; the non-contact ultrasonic interruption mode can achieve a more ideal interruption effect only by accurately controlling the ultrasonic focusing.
Therefore, the existing ultrasonic breaking equipment does not meet the accurate control requirement, and the total error is large in the non-contact breaking process, so that the final detection result is not ideal enough. Therefore, aiming at the defects in the existing equipment, a more reasonable technical scheme is required to be provided, and the technical problems in the prior art are solved.
SUMMERY OF THE UTILITY MODEL
The utility model provides a geometric focusing ultrasonic wave breaking device based on biological sample treatment, aiming at optimizing an ultrasonic transduction component of the breaking device, wherein ultrasonic waves emitted by a transducer are converged at a focusing center, and the converged ultrasonic waves carry sufficient energy to generate strong chopping effect; the non-contact ultrasonic interruption equipment has more accurate control on ultrasonic waves and more ideal interruption effect.
In order to realize the above effect, the utility model discloses a technical scheme does:
a geometric focusing ultrasonic wave breaking device based on biological sample processing comprises an ultrasonic transducer assembly and a sample placing platform, wherein the ultrasonic transducer assembly comprises a transducer, and the transducer comprises an arc-shaped concave emitting surface; the sample placing platform comprises a shearing tube for placing a biological sample, and the shearing tube is arranged at the focusing center of the concave emitting surface.
The ultrasonic breaking equipment disclosed above utilizes the characteristic that ultrasonic carries energy to converge the ultrasonic wave sent out from the concave emitting surface of the transducer, and at the converging central point, the energy carried by the ultrasonic wave reaches the maximum. Therefore, the sample placing platform is placed in the converging direction of the concave emitting surface, the shearing tube is positioned at the converging central point, and the shearing force applied to the biological sample in the shearing tube is the largest.
As a feasible selection, the utility model discloses optimize the transducer structure disclosed in the above-mentioned technical scheme, the transducer can dispose the arc for the indent, and concave transmitting surface can adopt the indent sphere in it, then assembles the centre of sphere point that the center is located the indent sphere. The ultrasonic wave attenuation device has the advantages that the distances from the ultrasonic waves emitted from each point of the concave spherical surface to the convergence center are equal, the ultrasonic waves in all directions can be considered to be equal in the same propagation medium, the convergence effect at the convergence center is better, and the control is more accurate; meanwhile, the spherical center point of the concave spherical surface is the placement position of the sample shearing tube, and the position confirmation is easy.
Further, the above description describes the sample placement platform, wherein the structure of the sample placement platform can place the cutting tube through a plurality of structures, and as an alternative, there are possible schemes: the sample placement platform still including the support that is used for fixed shearing pipe with be used for stabilizing the balancing weight of shearing the pipe, be provided with the protecting cover on the shearing pipe.
Still further, can optimize the structure of support, it is specific, the supporting structure be suspension structure, it is fixed in the top of transducer, make the focus center of shearing pipe suspension in the transducer, when the ultrasonic wave assembles, do not receive outside structural barrier, directly with energy transfer to shearing intraductal and break the processing to the sample.
Further, when the ultrasonic transducer assembly emits ultrasonic waves and controls convergence, a great amount of heat is generated, the interrupted ambient temperature is affected, and in order to avoid damage to the sample and the device caused by an excessively high ambient temperature, the ultrasonic transducer assembly is optimized here, as an option, the following feasible schemes are given: the ultrasonic energy conversion assembly further comprises a water tank piece which is connected with the energy converter in a matched mode, the concave emitting surface of the energy converter faces towards the cavity of the water tank piece, and the gathering center of the concave emitting surface is located in the cavity of the water tank piece.
Furthermore, the water level in the water tank needs to submerge the gathering center, so that the biological sample in the shearing pipe is interrupted in a proper temperature environment, the biological sample can be prevented from being damaged, the effect after interruption is more accurate, and when the water level does not meet the condition of submerging the gathering center, the interruption work is not required, so that the water tank is optimized, and as an option, the following feasible schemes are given out: the ultrasonic energy conversion assembly further comprises a liquid level sensor, and the liquid level sensor is arranged on the water tank piece and used for detecting the water level in the cavity of the water tank piece.
Still further, in the working process of the ultrasonic transducer assembly, the temperature in the water tank member tends to change and rise to a certain extent, so that the real-time monitoring of the temperature in the water tank member is particularly important, and the water tank member is optimized, as an option, the following feasible schemes are given out: the ultrasonic transducer assembly further comprises a temperature sensor, and the temperature sensor is arranged on the water tank piece and used for detecting the temperature in the cavity of the water tank piece.
And the breaking device comprises a controller for controlling the ultrasonic energy conversion component to be electrically connected, and the controller controls the ultrasonic energy conversion component to be opened and closed according to the received detection signal. The controller will stop operation of the ultrasonic transducer assembly when the received detection signal indicates that the liquid level within the basin member has not reached a predetermined height and/or the temperature within the basin member has exceeded a predetermined threshold.
Further, the water stored in the sink member can be used for alleviating the temperature rise, and the temperature control can be realized by heat conduction after the temperature of the stored water rises, so that the breaking device is optimized, and as an option, the following feasible schemes are given: the breaking equipment further comprises a first temperature control assembly, the first temperature control assembly comprises a refrigerating piece attached to the outer surface of the water tank piece, and a first circulating water heat transfer structure is arranged on the outer side of the refrigerating piece. The first temperature control assembly is used for guiding out the heat of the stored water in the water tank piece, and helps to reduce the water temperature in the water tank piece.
Still further, the heat back of storing water is derived to first temperature control subassembly, discharges the heat through certain mode again, realizes quick cooling, guarantees the control by temperature change ability, and the mode of heat discharge is various, and as an option, feasible scheme is given out here: the ultrasonic breaking equipment further comprises a cold discharging assembly, the cold discharging assembly comprises a water-cooling heat radiating pipe, the water-cooling heat radiating pipe is a water pipe communicated with the first circulating water heat transfer structure, the water-cooling heat radiating pipe is communicated with the first circulating water heat transfer structure to form a water-cooling heat radiating pump, the water-cooling heat radiating pump is used for promoting water circulation, and a heat radiating fan used for cooling is arranged at the position of the water-cooling heat radiating pipe. The first circulating water heat transfer structure absorbs heat at the refrigerating fins, the heat is led into the water-cooling heat dissipation row along with circulating water, and the heat is taken away by airflow of the heat dissipation fan at the water-cooling heat dissipation row, so that the circulating water is cooled.
Further, the breaking device disclosed above describes the ultrasound transducer assembly and the sample placement platform, and as for the coordination control of the ultrasound transducer assembly and the sample placement platform, other components of the breaking device need to coordinate, and the breaking device can implement the coordination of the ultrasound transducer assembly and the sample placement platform in multiple ways, as an option, a feasible solution is given here: the breaking equipment further comprises a control host, wherein a sample processing bin is arranged on the control host, and the transducer assembly and the sample placing platform are arranged in the sample bin.
Furthermore, a power supply is arranged on the control host and supplies power to the electric equipment such as the ultrasonic energy conversion component and the like; a host switch is also provided for turning the entire interrupting device on or off.
Still further, when the control host computer controls the ultrasonic transducer assembly and the like, the information of the control host computer is also fed back to the outside, the information is displayed for the staff, and the corresponding work information is expressed, as an option, a feasible scheme is given as follows: and a touch display screen for man-machine interaction is arranged on the control host.
Still further, the control host disclosed in the above solution is provided with a sample processing bin, and the sample processing bin is optimized here in order to keep the ultrasonic transducer assembly and the sample placement platform clean, as an option, a feasible solution is given as follows: the sample processing bin is provided with a bin door, the bin door is connected to the control host through a hinge in a rotating mode and used for opening and closing the sample processing bin, and the bin door is provided with a damping pad and a handle structure.
Still further, the utility model discloses optimize the door, it is specific, give up as following feasible scheme: the hinge arranged on the bin door is a damping hinge, so that the bin door can obtain a damping auxiliary effect when being overturned relative to the control host, wherein when the opening angle of the bin door is smaller than a first preset angle, the bin door can be slowly and automatically closed under the damping effect; when the opening angle of the bin door is larger than the second preset angle, the bin door can keep a static state under the damping effect. The shock pad that sets up in the edge of door can realize the cushioning effect at the door in-process of closing, noise abatement and collision.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the utility model discloses a contactless supersound breaks the mode, and the cross contamination problem of avoiding the sample that can be fine is solved because the measuring result deviation that cross contamination leads to from the source. Set up curved indent transmitting surface on the transducer, the focus center of transducer is the centre of sphere of indent transmitting surface promptly, adopts the principle of geometry focus supersound like this, and the accuracy of focus is better, so sets up the gathering that makes the ultrasonic wave more accurate and controllable, has reduced the error of breaking the result for measuring result is more accurate.
2. The utility model discloses set up the shearing tube and be used for holding the sample to make the sample realize broken and break in the shearing tube, its focus sound energy optimizes ultrasonic cavitation, allows more even sample treatment, has improved the efficiency and the repeatability of nucleic acid shearing.
3. The utility model discloses improvement operating personnel's that can be very big operating efficiency. And the full-automatic operation can greatly improve the consistency of the operation and avoid the result abnormity caused by personnel reasons.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only show some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic diagram of the overall structure of the breaking apparatus;
FIG. 2 is a schematic view of the overall structure of the interrupting device from another perspective;
FIG. 3 is a schematic view of the structure of the bin gate
FIG. 4 is a schematic diagram of the internal structural components of the breaking apparatus;
FIG. 5 is a schematic structural view of an ultrasonic transducer assembly;
FIG. 6 is an exploded schematic view of an ultrasonic transducer assembly;
FIG. 7 is a schematic structural view of a sample placement platform;
fig. 8 is an exploded schematic view of the sample placement platform.
In the above figures, the meanings of the reference symbols are as follows: 1. a control host; 2. a bin gate; 201. a hinge; 202. a vibration damping pad; 203. a handle structure; 3. a touch display screen; 4. an adjustable foot margin structure; 5. an air exhaust device; 6. a power source; 7. an ultrasonic transducer assembly; 701. an insulating platen; 702. sealing the pressure plate; 703. a sink member; 704. a liquid level sensor; 705. a transducer; 706. a concave emitting surface; 708. a temperature sensor; 8. a sample placement platform; 801. a protective cover; 802. a support; 803. a balancing weight; 804. shearing a pipe; 9. a water-cooling heat dissipation pump; 10. a cold row assembly; 11. a first temperature control assembly; 1101. a refrigeration plate; 1102. a circulating water tank.
Detailed Description
The present invention will be further explained with reference to the drawings and the embodiments.
It should be noted that the description of the embodiments is provided to help understanding of the present invention, but the present invention is not limited thereto. Specific structural and functional details disclosed herein are merely illustrative of example embodiments of the invention. The present invention may, however, be embodied in many alternate forms and should not be construed as limited to the embodiments set forth herein.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments of the invention. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises," "comprising," "includes," and/or "including," when used herein, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, numbers, steps, operations, elements, components, and/or groups thereof.
It should also be noted that, in some alternative implementations, the functions/acts noted may occur out of the order noted in the figures. For example, two figures shown in succession may, in fact, be executed substantially concurrently, or the figures may sometimes be executed in the reverse order, depending upon the functionality/acts involved.
In the following description, specific details are provided to facilitate a thorough understanding of example embodiments. However, it will be understood by those of ordinary skill in the art that the example embodiments may be practiced without these specific details. For example, systems may be shown in block diagrams in order not to obscure the examples in unnecessary detail. In other instances, well-known processes, structures and techniques may be shown without unnecessary detail in order to avoid obscuring example embodiments.
Examples
As shown in fig. 1 to 8, the present embodiment provides a geometric focusing ultrasonic breaking apparatus based on biological sample processing, including an ultrasonic transducer assembly 7 and a sample placing platform 8, where the ultrasonic transducer assembly 7 includes a transducer 705, and the transducer 705 includes an arc-shaped concave emitting surface 706; the sample placement platform 8 comprises a cutting tube 804 for placing a biological sample, the cutting tube 804 being disposed in the focal center of the concave emitting surface 706.
The ultrasonic breaking device disclosed above uses the characteristic of ultrasonic energy carrying to converge the ultrasonic waves emitted from the concave emitting surface 706 of the transducer 705, and at the converging center point, the energy carried by the ultrasonic waves is maximized. Therefore, the sample placement platform 8 is placed in the converging direction of the concave emitting surface 706, and the shearing tube 804 is located at the converging central point, so that the shearing force applied to the biological sample in the shearing tube 804 is the largest.
As a feasible option, the utility model discloses optimize the transducer 705 structure disclosed in the above-mentioned technical scheme, transducer 705 can dispose the arc for the indent, and its interior concave transmitting surface 706 can adopt the indent sphere, then assembles the center of sphere point that the center is located the interior concave sphere. The ultrasonic wave attenuation device has the advantages that the distances from the ultrasonic waves emitted from each point of the concave spherical surface to the convergence center are equal, the ultrasonic waves in all directions can be considered to be equal in the same propagation medium, the convergence effect at the convergence center is better, and the control is more accurate; meanwhile, the spherical center point of the concave spherical surface is the place where the sample shearing pipe 804 is placed, and the position confirmation is easy.
The core of the ultrasound interruption device is the conversion of electrical energy into mechanical energy by means of a control board and a piezoelectric element, in the present embodiment, the generation of the signal emitted by the transducer 705 is geometric focusing, and the radius of curvature of the element of the transducer 705 is modified so that it is equal to the focal length. The wave with the wavelength more than 1mm is crushed and sheared at the frequency more than 500KHZ, and the effect is remarkable.
The above description has been made of the sample placement stage 8, wherein the structure of the sample placement stage 8 can place the cutting tube 804 through a variety of structures, as an alternative, there are possible solutions: the sample placement platform 8 further comprises a bracket 802 for fixing the shearing pipe 804 and a balancing weight 803 for stabilizing the shearing pipe 804, and a protective cover 801 is arranged on the shearing pipe 804.
The structure of the support 802 can be optimized, specifically, the support 802 is a suspension structure and is fixed above the transducer 705, so that the shearing tube 804 is suspended at the focusing center of the transducer 705, and when ultrasonic waves converge, the ultrasonic waves are not blocked by an external structure, energy is directly transmitted into the shearing tube 804, and a sample is interrupted.
Preferably, the support 802 is a Y-shaped support 802. The function of Y type support 802 is fixed shear pipe 804, and the function of protecting cover 801 is that the sample can not appear overflowing breaking the in-process, and balancing weight 803 then provides a gravity, prevents that shear pipe 804 from appearing floating when the aquatic is soaked, also prevents to break the effect that the influence supersound breaks in-process rocking back and forth simultaneously.
When the ultrasonic transducer assembly 7 emits ultrasonic waves and controls convergence, a great amount of heat is generated to affect the interrupted ambient temperature, and in order to avoid damage to the sample and the equipment caused by the overhigh ambient temperature, the ultrasonic transducer assembly is optimized here, as an option, the following feasible schemes are given out: the ultrasonic transducer assembly 7 further comprises a water tank member 703 connected with the transducer 705 in a matching manner, the concave emitting surface 706 of the transducer 705 faces the cavity of the water tank member 703, and the gathering center of the concave emitting surface 706 is positioned in the cavity of the water tank member 703.
Preferably, the water tank is made of metal with good heat conduction, and aims to store water and realize quick heat exchange.
In the present embodiment, the ultrasonic transducer assembly 7 is configured such that: the energy converter 705 is a spherical arc-shaped plate, the water tank part 703 is vertically arranged, the energy converter 705 is arranged at the lower part of the water tank part 703, and the upper surface edge of the energy converter 705 is insulated from the water tank part 703 through insulating sealant; a sealing pressure plate 702 is arranged on the lower side of the transducer 705, an insulating pressure plate 701 is further arranged below the sealing pressure plate 702, and the transducer 705 is insulated from other working components of the breaking device by the insulating pressure plate 701.
The water level in the sink member 703 needs to submerge the collection center, so that the biological sample in the shearing pipe 804 is broken in a suitable temperature environment, and thus the biological sample is prevented from being damaged, the broken effect is more accurate, and when the water level does not meet the condition of submerging the collection center, the work should not be interrupted, so that the sink member 703 is optimized, as an option, the following feasible schemes are given: the ultrasonic transducer assembly 7 further comprises a liquid level sensor 704, and the liquid level sensor 704 is disposed on the water tank member 703 and is used for detecting the water level in the cavity of the water tank member 703. In this embodiment, the level sensor 704 is in communication with the water tank and is sealed to prevent water leakage.
The function of the level sensor 704 is to detect if the water level has reached a minimum level, and when it falls below the minimum level, it will alarm and the instrument will not be able to initiate an interruption. The liquid level sensor 704 is sealed from the water tank to prevent water leakage.
In the working process of the ultrasonic transducer assembly 7, if no interference is caused, the temperature inside the water channel 703 will tend to change and rise to a certain extent, so that it is particularly important to monitor the temperature inside the water channel 703 in real time, and therefore, the water channel 703 is optimized, as an option, the following feasible schemes are given: the ultrasonic transducer assembly 7 further comprises a temperature sensor 708, and the temperature sensor 708 is disposed on the water tank member 703 and is used for detecting the temperature in the cavity of the water tank member 703.
The liquid level sensor 704 and the temperature sensor 708 are used for monitoring in real time and transmitting detection signals back, the breaking device comprises a controller used for controlling the electric connection of the ultrasonic energy conversion component, and the controller controls the opening and closing of the ultrasonic energy conversion component 7 according to the received detection signals. When the received detection signal indicates that the liquid level in the basin 703 does not reach a predetermined height and/or the temperature in the basin 703 exceeds a predetermined threshold, the controller will stop the operation of the ultrasonic transducer assembly 7.
Furthermore, the function of the temperature sensor 708 is to collect the real-time temperature of the water in the tank, ensuring that the ultrasound process is in a constant temperature process. And when the temperature change does not meet the preset condition, early warning is carried out.
The water stored in the basin 703 can be used to alleviate the temperature rise, and the temperature control can be realized by heat conduction after the temperature of the stored water rises, so as to optimize the breaking device, as an option, the following feasible schemes are given: the breaking equipment further comprises a first temperature control assembly 11, wherein the first temperature control assembly 11 comprises a refrigerating sheet 1101 attached to the outer surface of the water tank member 703, and a first circulating water heat transfer structure is arranged on the outer side of the refrigerating sheet 1101. The first temperature control assembly 11 is used for guiding out the heat of the stored water in the water tank 703, and helps to reduce the temperature of the water in the water tank 703.
The first circulating water heat transfer structure comprises a circulating water tank 1102 attached to the refrigeration sheet 1101, and the circulating water tank 1102 is communicated with a circulating water source, so that heat on the refrigeration sheet 1101 is taken away by water flow in the circulating water tank 1102.
First temperature control unit 11 exports the heat of storage water the back, discharges the heat through certain mode again, realizes quick cooling, guarantees the control by temperature change ability, and the mode of heat discharge is various, and as an option, here gives out feasible scheme: the supersound breaks equipment and still includes cold row's subassembly 10, cold row's subassembly 10 include that the water-cooling dispels the heat and arranges, the water-cooling dispel the heat arrange for the water pipe of the first circulating water heat transfer structure of intercommunication, the water-cooling dispels the heat arrange with first circulating water heat transfer structure intercommunication water-cooling heat dissipation pump 9, water-cooling heat dissipation pump 9 is used for promoting hydrologic cycle, the department of arranging of water-cooling heat dissipation is provided with and is used for refrigerated radiator fan. The first circulating water heat transfer structure absorbs heat at the position of the refrigeration sheet 1101, the heat is led into the water-cooling heat dissipation row along with the circulating water, and the heat is taken away by airflow of the heat dissipation fan at the position of the water-cooling heat dissipation row, so that the cooling of the circulating water is realized.
The breaking device disclosed above describes the ultrasonic transducer assembly 7 and the sample placement platform 8, and as for the coordination control of the ultrasonic transducer assembly 7 and the sample placement platform 8, other components of the breaking device need to be coordinated, and the breaking device can implement the coordination of the ultrasonic transducer assembly 7 and the sample placement platform 8 in multiple ways, and as an option, a feasible scheme is given here: the breaking device further comprises a control host 1, wherein a sample processing bin is arranged on the control host 1, and the transducer 705 assembly and the sample placing platform 8 are arranged in the sample bin.
The control host 1 is provided with a power supply 6, and the power supply 6 supplies power for electric equipment such as an ultrasonic transducer assembly 7 and the like; a host switch is also provided for turning the entire interrupting device on or off. In this embodiment, at least one three-in-one filter switch is provided, which includes integrated filtering, over-current protection and switching functions.
When the control host 1 controls the ultrasonic transducer assembly 7, its own information is also fed back to the outside, and the information is presented to the staff to express the corresponding working information, as an option, a feasible solution is given here: and a touch display screen 3 for man-machine interaction is arranged on the control host 1.
Preferably, the touch display screen 3 can select different resolution sizes and touch forms according to different requirements, so as to achieve better human-computer interaction experience.
The control host 1 comprises a shell, a closed cavity is formed in the shell, a plurality of air exhaust devices 5 are arranged on the shell, an air outlet is formed in the shell, and a ventilation opening, a protective net and an exhaust fan are arranged at the air outlet.
Preferably, the vent is in the shape of a strip, which gives consideration to appearance, noise and heat dissipation efficiency.
And an adjustable foot structure 4 is further arranged below the shell, so that the liquid level sensor 704 is leveled for use when being installed, and the phenomenon that the liquid level sensor 704 is misreported or cannot be used due to unevenness is prevented.
The surface of the shell is coated with a heat insulation material, so that heat loss is reduced to the maximum extent.
The control unit 1 disclosed in the above-mentioned solution is provided with a sample processing chamber, which is optimized here in order to keep the ultrasonic transducer assembly 7 and the sample placement platform 8 clean, and as an option, possible solutions are given: the sample processing bin is provided with a bin door 2, the bin door 2 is rotatably connected to the control host 1 through a hinge 201 and used for opening and closing the sample processing bin, and the bin door 2 is provided with a damping pad 202 and a handle structure 203.
The utility model discloses optimize door 2, it is concrete, give up as following feasible scheme: the hinge 201 arranged on the bin gate 2 is a hinge 201 with damping, so that when the bin gate 2 is turned over relative to the control host 1, the auxiliary effect of damping can be obtained, wherein when the opening angle of the bin gate 2 is smaller than a first preset angle, the bin gate 2 can be slowly and automatically closed under the effect of damping; when the opening angle of the bin gate 2 is larger than the second preset angle, the bin gate 2 will keep a static state under the damping effect. The shock pad that sets up in the edge of door 2 can realize the cushioning effect at door 2 in-process of closing, noise abatement and collision.
In this embodiment, the control host 1 is connected to a network, and can report the state of a local instrument and receive a remote instruction through an RS485 bus.
The above embodiments are just examples of the present invention, but the present invention is not limited to the above alternative embodiments, and those skilled in the art can obtain other various embodiments by arbitrarily combining the above embodiments, and any one can obtain other various embodiments by the teaching of the present invention. The above detailed description should not be taken as limiting the scope of the invention, which is defined in the following claims, and which can be used to interpret the claims.

Claims (10)

1. A geometrically focused ultrasound wave interruption device based on biological sample processing, comprising an ultrasound transducer assembly (7) and a sample placement platform (8), characterized in that: the ultrasonic transducer assembly (7) comprises a transducer (705), wherein the transducer (705) comprises an arc-shaped concave emitting surface (706); the sample placing platform (8) comprises a shearing tube (804) for placing a biological sample, and the shearing tube (804) is arranged at the focusing center of the concave emitting surface (706).
2. A geometric focused ultrasound interruption device based on biological sample processing according to claim 1, characterized in that: sample place platform (8) still include support (802) that are used for fixed shearing pipe (804) and balancing weight (803) that are used for stable shearing pipe (804), be provided with protecting cover (801) on shearing pipe (804).
3. A geometric focused ultrasound interruption device based on biological sample processing according to claim 1, characterized in that: the ultrasonic transducer assembly (7) further comprises a water tank piece (703) which is connected with the transducer (705) in a matching mode, the concave emitting surface (706) of the transducer (705) faces to the cavity of the water tank piece (703), and the gathering center of the concave emitting surface (706) is located in the cavity of the water tank piece (703).
4. A geometric focused ultrasound interruption device based on biological sample processing according to claim 3 characterized by: the ultrasonic transducer assembly (7) further comprises a liquid level sensor (704), and the liquid level sensor (704) is arranged on the water tank piece (703) and is used for detecting the water level in the cavity of the water tank piece (703).
5. A geometric focused ultrasound interruption device based on biological sample processing according to claim 3 or 4 characterized in that: the ultrasonic transducer assembly (7) further comprises a temperature sensor (708), and the temperature sensor (708) is arranged on the water tank piece (703) and used for detecting the temperature in the cavity of the water tank piece (703).
6. A geometric focused ultrasound interruption device based on biological sample processing according to claim 3 or 4 characterized in that: still include first temperature control subassembly (11), first temperature control subassembly (11) including laminating in refrigeration piece (1101) of basin piece (703) surface, refrigeration piece (1101) outside is provided with first circulating water heat transfer structure.
7. A geometric focused ultrasound interruption device based on biological sample processing according to claim 6 characterized by: still include cold row subassembly (10), cold row subassembly (10) arrange including the water-cooling heat dissipation, the water-cooling heat dissipation arrange for the water pipe of the first circulating water heat transfer structure of intercommunication, the water-cooling heat dissipation arrange with first circulating water heat transfer structure intercommunication water-cooling heat dissipation pump (9), water-cooling heat dissipation pump (9) are used for promoting hydrologic cycle, the department of arranging of water-cooling heat dissipation is provided with and is used for refrigerated radiator fan.
8. A geometric focused ultrasound interruption device based on biological sample processing according to claim 1, characterized in that: the device is characterized by further comprising a control host (1), wherein a sample processing bin is arranged on the control host (1), and the transducer (705) assembly and the sample placement platform (8) are arranged in the sample bin.
9. A geometric focused ultrasound interruption device based on biological sample processing according to claim 8, characterized in that: and a touch display screen (3) for man-machine interaction is arranged on the control host (1).
10. A geometric focused ultrasound interruption device based on biological sample processing according to claim 8, characterized in that: the sample treatment bin is provided with a bin door (2), the bin door (2) is rotatably connected to the control host (1) through a hinge (201) and used for opening and closing the sample treatment bin, and a damping pad (202) and a handle structure (203) are arranged on the bin door (2).
CN202020589220.3U 2020-04-20 2020-04-20 Geometric focusing ultrasonic wave breaking equipment based on biological sample treatment Active CN211999748U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113457759A (en) * 2021-06-15 2021-10-01 黄怀 Ice bath box for molecular diagnosis laboratory

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113457759A (en) * 2021-06-15 2021-10-01 黄怀 Ice bath box for molecular diagnosis laboratory

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