CN113439904A - Jacket for wet bag treatment of skin diseases - Google Patents

Jacket for wet bag treatment of skin diseases Download PDF

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Publication number
CN113439904A
CN113439904A CN202110729273.XA CN202110729273A CN113439904A CN 113439904 A CN113439904 A CN 113439904A CN 202110729273 A CN202110729273 A CN 202110729273A CN 113439904 A CN113439904 A CN 113439904A
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China
Prior art keywords
wet
treatment
skin
pack
coat
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Pending
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CN202110729273.XA
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Chinese (zh)
Inventor
黄弢
冯磊
祁正飞
刘丹
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Suzhou Xuan Medical Intelligence Medical Technology Co ltd
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Suzhou Xuan Medical Intelligence Medical Technology Co ltd
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Priority to CN202110729273.XA priority Critical patent/CN113439904A/en
Publication of CN113439904A publication Critical patent/CN113439904A/en
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    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/12Surgeons' or patients' gowns or dresses
    • A41D13/1236Patients' garments
    • A41D13/1245Patients' garments for the upper part of the body
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00Materials specially adapted for outerwear
    • A41D31/02Layered materials
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00Materials specially adapted for outerwear
    • A41D31/04Materials specially adapted for outerwear characterised by special function or use
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00Materials specially adapted for outerwear
    • A41D31/04Materials specially adapted for outerwear characterised by special function or use
    • A41D31/06Thermally protective, e.g. insulating
    • A41D31/065Thermally protective, e.g. insulating using layered materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/04Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
    • A61K35/06Mineral oils, e.g. paraffinic oils or aromatic oils based on aromatic hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D2400/00Functions or special features of garments
    • A41D2400/32Therapeutic use

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Textile Engineering (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Thermal Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a jacket for wet bag treatment of skin diseases, which belongs to the technical field of wet bag treatment and comprises an inner layer, wherein the jacket is made of elastic materials, the inner layer is close to the skin and has a moisturizing function, and the outer layer has a heat preservation function and water locking performance and can prevent evaporation.

Description

Jacket for wet bag treatment of skin diseases
Technical Field
The invention relates to the technical field of wet bag treatment, in particular to an upper garment for wet bag treatment of skin diseases.
Background
Wet pack therapy is a common treatment mode for skin diseases, and generally refers to a special treatment mode of packaging by using auxiliary materials on the basis of external medicines and lubricants. In recent years, pouched therapy has been used for the treatment of pruritic skin diseases such as atopic dermatitis, psoriasis, prurigo nodularis, etc. in children and adults at home and abroad, and has been confirmed as an effective treatment means. In the guidelines for the treatment of atopic dermatitis, which are established in succession by the european, american and chinese dermatology association, the wet-mass treatment of acute exacerbation or persistent moderately severe atopic dermatitis is recommended.
The wet pack treatment is to apply the treatment medicine on the skin, and also to apply the moisturizing auxiliary material on the skin to ensure the curative effect of the wet pack treatment. Dressings are generally divided into two layers, the inner layer being moist to provide moisture retention and the outer layer being dry to provide evaporation prevention and heat retention. The dressing commonly used at present comprises a bandage, gauze, a tubular bandage and the like, and in addition, the dressing is also often simplified into cotton clothes (such as underwear like autumn clothes and the like) which are more easily obtained in clinical application. However, the above wet-packing methods all have their own disadvantages: the bandage special for wet wrapping is complex to operate, more labor and time cost are consumed, and the comfort degree of a patient is poor when the underwear is used for replacing the patient. In addition, the coat can cause inconvenient movement, discomfort due to dampness and maladjustment of temperature during wrapping, can also cause adverse reactions such as secondary infection, e.g. folliculitis, impetigo, furuncle, herpes simplex, molluscum contagiosum and the like, and is seriously infected by pseudomonas at the skin fold part, so the coat for wet-wrapping treatment of skin diseases is provided.
Disclosure of Invention
The invention aims to provide a coat for wet bag treatment of skin diseases, which solves the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a jacket for wet bag treatment of skin diseases comprises an inner layer, wherein an outer layer is arranged outside the inner layer.
An operation method of a coat for wet bag treatment of skin diseases specifically comprises the following steps:
s1: 12 cases of atopic dermatitis patients were selected, and the atopic dermatitis patients were not treated systemically for atopic dermatitis other than oral antihistamine one month before the group administration;
s2: all study subjects completed wet-pack treatment under hospitalization, and patients first bathed with mild body wash, then applied the halometasone cream to the trunk and upper limb skin lesions, massaged for 5 minutes until completely absorbed, and applied vaseline ointment to the whole body at a daily dose of 100g per dose of halometasone cream, 15g per time;
s3: the patient wears the coat, the inner layer is close to the skin and has the moisturizing function, the outer layer has the heat preservation function and the water locking property and prevents evaporation, the wet-pack treatment lasts for 2 hours each time, and the body is smeared with moisturizing cream again after the coat is taken off;
s4: the treatment was performed 2 times a day for a total treatment period of 7 days. The effectiveness and safety of wet pack therapy was assessed at day 8.
Compared with the prior art, the invention has the beneficial effects that: the elastic coat is arranged, the inner layer is close to the skin and has a moisturizing function, the outer layer has a heat preservation function and water locking performance, evaporation is prevented and treated, the coat is convenient to put on and take off, time and labor are saved, the coat can be repeatedly cleaned, and the defects of skin infection and other auxiliary materials used in the traditional wet bag caused by repeated wearing are overcome.
Drawings
FIG. 1 is a schematic view of the structure of the present invention.
In the figure: 1. an inner layer; 2. and (4) an outer layer.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides a technical scheme that: the utility model provides a jacket for wet package of skin disease treatment, please refer to and draw close to 1, including inlayer 1, the outside of inlayer 1 is provided with outer 2, this jacket is the elasticity material jacket, skin one deck is pressed close to promptly to inlayer 1, it has the function of moisturizing, outer 2 has heat preservation function and locking water nature, prevention and cure evaporation, set up through prior art can, through setting up the elasticity material jacket, skin one deck is pressed close to promptly to inlayer 1 has the function of moisturizing, outer 2 has heat preservation function and locking water nature, prevention and cure evaporation, this jacket is worn to take off conveniently, time saving and labor saving, and can rinse repeatedly, overcome the drawback of wearing the used auxiliary material of traditional wet package such as skin infection that leads to repeatedly.
A method for operating a coat for wet pack treatment of skin diseases comprises the following steps:
s1: 12 cases of atopic dermatitis patients were selected, diagnosed as atopic dermatitis according to Williams criteria and having an atopic dermatitis SCORAD score of > 50 points, aged >18 years, and were not treated systemically with other atopic dermatitis except oral antihistamines in the month prior to enrollment, signed an informed consent, with the exclusion criteria: skin lesions have secondary virus, bacterial or fungal infection, malignant tumors, autoimmune diseases, serious systemic infectious diseases, mental diseases, serious liver and kidney or vascular diseases, are allergic to halometasone ointment or vaseline ointment, cannot follow the research scheme, and have poor compliance;
s2: all study subjects completed wet-pack treatment under hospitalization, and patients first bathed with mild body wash, then applied the halometasone cream to the trunk and upper limb skin lesions, massaged for 5 minutes until completely absorbed, and applied vaseline ointment to the whole body at a daily dose of 100g per dose of halometasone cream, 15g per time;
s3: when a patient wears the coat, the inner layer 1 is close to the skin and has a moisturizing function, the outer layer 2 has a heat preservation function and water locking performance and can prevent evaporation, the wet-pack treatment lasts for 2 hours each time, and after the coat is taken off, moisturizing cream is smeared on the whole body again;
s4: the treatment was performed 2 times a day for a total treatment period of 7 days. The effectiveness and safety of wet pack therapy was assessed at day 8, effectiveness assessment: the SCORAD score for atopic dermatitis, the overall investigator assessment (IGA) score, and the dermatological quality of life index (DLQI) score were all performed by dermatologists, patients were self-rated for itching symptoms using Visual Analogue Scale (VAS), SCORAD score ranged from 0 to 103, and severity of atopic dermatitis was classified as mild, moderate, and severe. Safety assessments when score 0-24 (mild), 25-50 (moderate), 51-103 (severe): adverse event assessment severity was determined by communicating with the patient, recording, and laboratory blood draws to detect changes in serum cortisol levels at 0 and 8 early days before and after treatment.
The study is provided for inclusion in 12 patients with severe atopic dermatitis, wherein 8 men and 4 women have the age of 27-85 years, the average age is 58.91 +/-18.87 years, the median disease course is 27.5 months, the body mass index is 17.58-27.04, and the average body mass index is 22.20 +/-5.68.
As a result: 12 patients who were wet-packed, had a mean score decrease from 68.59 + -8.61 before treatment to 28.79 + -5.16 after treatment (95% CI: 35.18-44.42, P <0.001), a percentage decrease in score varying from 41.7% to 66.76%, compared to the baseline-time score, the post-wet-pack treatment pruritus VAS score (7.5 + -1.17 vs. 2.75 + -0.62, 95% CI: 4.14-5.36, p <0.001), the pre-and post-treatment IGA score (4.08 + -0.51 vs. 1.83 + -0.39, 95% CI: 1.96-2.54, p <0.001), and the DQLI score (13.83 + -2.79 vs. 1.83 + -0.39, p <0.001), were all significantly reduced in wet-pack treatment, while patient serum cortisol levels were not significantly affected before and after treatment (Day 0: 10.82 + -1.35 μ g/dL vs. Day 8: 9.46 + -2.20 μ g/dL, 95% dL: -0.48-3.21, p = 0.133).
Adverse events: all patients do not have the disadvantages of inconvenient movement, discomfort due to dampness and aversion to cold, and do not have the disadvantages of viral, fungal or bacterial infection and the like, and do not have the discomfort of fever, cough and the like.
The results show that the wet-pack treatment seems to effectively relieve the pruritus symptom of the severe AD patient, improve the skin damage condition and improve the life quality of the patient, and the results prove that the curative effect of the invention is exact, the implementation method of the wet-pack treatment of the invention has no adverse reactions such as inconvenient movement, uncomfortable humidity and the like, and also has no complications such as skin infection and the like, which shows that the invention has good safety, and overcomes the defects of more adverse reactions and potential risks in the traditional wet-pack treatment method.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (2)

1. A jacket for wet pack treatment of skin diseases, comprising an inner layer (1), characterized in that: an outer layer (2) is arranged outside the inner layer (1).
2. The method of operating a coat for wet pack therapy of skin disorders according to claim 1, wherein: the method comprises the following steps:
s1: 12 cases of atopic dermatitis patients were selected, and the atopic dermatitis patients were not treated systemically for atopic dermatitis other than oral antihistamine one month before the group administration;
s2: all study subjects completed wet-pack treatment under hospitalization, and patients first bathed with mild body wash, then applied the halometasone cream to the trunk and upper limb skin lesions, massaged for 5 minutes until completely absorbed, and applied vaseline ointment to the whole body at a daily dose of 100g per dose of halometasone cream, 15g per time;
s3: when a patient wears the coat, the inner layer (1) is close to the skin and has a moisturizing function, the outer layer (2) has a heat preservation function and a water locking property, evaporation is prevented and treated, the wet-pack treatment lasts for 2 hours each time, and moisturizing cream is smeared on the whole body again after the coat is taken off;
s4: the treatment was performed 2 times daily for a total treatment period of 7 days, and the effectiveness and safety of wet-pack treatment was assessed at day 8.
CN202110729273.XA 2021-06-29 2021-06-29 Jacket for wet bag treatment of skin diseases Pending CN113439904A (en)

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Application Number Priority Date Filing Date Title
CN202110729273.XA CN113439904A (en) 2021-06-29 2021-06-29 Jacket for wet bag treatment of skin diseases

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102379893A (en) * 2011-08-29 2012-03-21 江苏德达医药科技有限公司 Compound pharmaceutical composition of iodine polymer and glucocorticosteroid for treating dermatitis
KR20130102332A (en) * 2012-03-07 2013-09-17 연세대학교 원주산학협력단 Wet-wrap dressing gown
US20160324872A1 (en) * 2014-01-08 2016-11-10 Mayo Foundation For Medical Education And Research Impregnated dressings for treating dermatological disorders
CN107519180A (en) * 2016-06-20 2017-12-29 天津金耀集团有限公司 Dermopharmaceutical composition using Halometasone as active component
CN211067228U (en) * 2019-08-07 2020-07-24 成都市第二人民医院 Reusable moisture-keeping clothes
CN211156622U (en) * 2019-09-04 2020-08-04 南方医科大学皮肤病医院 A treatment device for wet parcel therapy

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102379893A (en) * 2011-08-29 2012-03-21 江苏德达医药科技有限公司 Compound pharmaceutical composition of iodine polymer and glucocorticosteroid for treating dermatitis
KR20130102332A (en) * 2012-03-07 2013-09-17 연세대학교 원주산학협력단 Wet-wrap dressing gown
US20160324872A1 (en) * 2014-01-08 2016-11-10 Mayo Foundation For Medical Education And Research Impregnated dressings for treating dermatological disorders
CN107519180A (en) * 2016-06-20 2017-12-29 天津金耀集团有限公司 Dermopharmaceutical composition using Halometasone as active component
CN211067228U (en) * 2019-08-07 2020-07-24 成都市第二人民医院 Reusable moisture-keeping clothes
CN211156622U (en) * 2019-09-04 2020-08-04 南方医科大学皮肤病医院 A treatment device for wet parcel therapy

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Application publication date: 20210928