CN113427545A - Mesenchymal stem cell culture umbilical cord tissue dicer - Google Patents

Mesenchymal stem cell culture umbilical cord tissue dicer Download PDF

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Publication number
CN113427545A
CN113427545A CN202110824343.XA CN202110824343A CN113427545A CN 113427545 A CN113427545 A CN 113427545A CN 202110824343 A CN202110824343 A CN 202110824343A CN 113427545 A CN113427545 A CN 113427545A
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CN
China
Prior art keywords
umbilical cord
cord tissue
dicer
mesenchymal stem
stem cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202110824343.XA
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Chinese (zh)
Inventor
张斌
别庆丽
吴佩佩
许文荣
钱晖
何宝玉
王凤鸽
冯雪芹
赵柔
魏利
梁敬
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Individual
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202110824343.XA priority Critical patent/CN113427545A/en
Publication of CN113427545A publication Critical patent/CN113427545A/en
Withdrawn legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D3/00—Cutting work characterised by the nature of the cut made; Apparatus therefor
    • B26D3/18—Cutting work characterised by the nature of the cut made; Apparatus therefor to obtain cubes or the like
    • B26D3/20—Cutting work characterised by the nature of the cut made; Apparatus therefor to obtain cubes or the like using reciprocating knives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D1/00—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor
    • B26D1/01—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work
    • B26D1/04—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member
    • B26D1/06—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates
    • B26D1/08—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates of the guillotine type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D1/00—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor
    • B26D1/01—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work
    • B26D1/04—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member
    • B26D1/06—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates
    • B26D1/08—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates of the guillotine type
    • B26D1/085—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates of the guillotine type for thin material, e.g. for sheets, strips or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D5/00—Arrangements for operating and controlling machines or devices for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D5/08—Means for actuating the cutting member to effect the cut
    • B26D5/16—Cam means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D7/06—Arrangements for feeding or delivering work of other than sheet, web, or filamentary form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D7/06—Arrangements for feeding or delivering work of other than sheet, web, or filamentary form
    • B26D7/0625—Arrangements for feeding or delivering work of other than sheet, web, or filamentary form by endless conveyors, e.g. belts

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  • Life Sciences & Earth Sciences (AREA)
  • Forests & Forestry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention discloses an umbilical cord tissue dicer for culturing mesenchymal stem cells, which relates to the technical field of mechanical equipment, and mainly comprises a main frame, a dicer system, a conveying system and a driving system; the dicing system and the conveying system are both arranged at the top of the main frame, and the dicing system is arranged on one side of the conveying system; the driving system is used for respectively driving the dicing system and the conveying system. The driving system respectively drives the cutting system and the conveying system; wherein, conveying system can carry out step-by-step transport to the umbilical cord tissue, makes the transport distance of umbilical cord tissue every time the same, and the stripping and slicing system cuts into 1mm to umbilical cord tissue when carrying the clearance2Tiny tissue blocks, ensuring the cuttingUniformity and uniformity of thickness, width, length.

Description

Mesenchymal stem cell culture umbilical cord tissue dicer
Technical Field
The invention relates to the technical field of mechanical equipment, in particular to an umbilical cord tissue dicer for culturing mesenchymal stem cells.
Background
The mesenchymal stem cell is an adult stem cell, exists in tissues such as umbilical cord, bone marrow, fat, umbilical cord blood and the like, and has strong self-renewal and multi-embryo layer differentiation capacity. Research shows that the medicine has obvious curative effect on immunoregulation and promoting tissue repair, and is widely used for clinical research and treatment of various major diseases such as rheumatoid arthritis, lupus erythematosus, graft-versus-host disease, hepatic fibrosis and the like.
The umbilical cord mesenchymal stem cells are extracted from the umbilical cord tissue of the newborn after full-term delivery and umbilical cord rupture, have the advantages of rich sources, no harm to the body, strong proliferation capacity, multi-embryo layer differentiation capacity, low immunogenicity and the like, and are accepted and applied by more and more professionals.
Before extracting the mesenchymal stem cells in the umbilical cord tissue, the umbilical cord tissue needs to be cut into 1mm2The tissue blocks are cultured, at present, the tissue blocks are trimmed manually, but the tissue blocks are time-consuming, labor-consuming and difficult to achieve with the thickness of 1mm2Therefore, a cutting machine is needed for cutting umbilical cord tissues, so that the culture standard of mesenchymal stem cells is unified, and the cutting is improvedThe efficiency of (c).
Disclosure of Invention
In order to solve the technical problems, the invention provides an umbilical cord tissue dicer for culturing mesenchymal stem cells, which is used for dicing umbilical cord tissues.
In order to achieve the purpose, the invention provides the following scheme:
the invention provides an umbilical cord tissue dicer for culturing mesenchymal stem cells, which comprises a main frame, a dicer system, a conveying system and a driving system, wherein the main frame is provided with a main shaft; the dicing system and the conveying system are both arranged at the top of the main frame, and the dicing system is arranged on one side of the conveying system; the driving system is used for respectively driving the dicing system and the conveying system.
Optionally, the umbilical cord tissue dicer for mesenchymal stem cell culture further comprises a control system, the control system is electrically connected with the driving system, and the control system is used for controlling the output of the driving system.
Optionally, the dicing system comprises a guide mechanism, a cutter and a first transmission mechanism; the cutter is arranged on the guide mechanism, and the first transmission mechanism is arranged between the guide mechanism and the driving system.
Optionally, the guide mechanism comprises a guide rail, a slide block, a cross beam and a tool rest; the guide rail is fixedly connected with the main frame; the sliding block is arranged on the guide rail in a sliding manner, and the end part of the beam is connected with the sliding block; the knife rest is arranged in the middle of the cross beam, and the cutter is arranged on the knife rest.
Optionally, the first transmission mechanism includes a main shaft, an eccentric wheel assembly, a counterweight, a first connecting rod and a second connecting rod; the main shaft is in transmission connection with the driving system; the eccentric wheel assembly and the balance weight are both arranged on the main shaft; one end of the first connecting rod is connected with the top of the eccentric wheel assembly, the other end of the first connecting rod is rotatably connected with one end of the second connecting rod, and the other end of the second connecting rod is connected with the guide mechanism.
Optionally, the conveying system comprises a conveying belt, a press roller, a pressure adjusting structure and a second transmission mechanism; the conveying belt is arranged below the compression roller, and the compression roller is arranged in the middle of the bottom of the pressure adjusting structure; the conveying belt and the press roller are in transmission connection with the driving system through the second transmission mechanism respectively.
Optionally, the pressure adjusting structure comprises a screw, a hanger rod, a hanger, a guide rod, a connecting beam and a roller frame; the screw rod is arranged at the top of the main frame along the vertical direction, and the hanging rod is arranged on the screw rod through an adjusting nut; the hanger is arranged right below the suspender, and the bottom of the hanger is in sliding connection with the main rack through a guide rod; an elastic part is arranged between the hanging rod and the hanging bracket; the end part of the connecting beam is fixedly connected with the guide rod, the roller frame is arranged in the middle of the connecting beam, and the press roller is arranged on the lower part of the roller frame.
Optionally, the second transmission mechanism comprises a roll shaft; the roller shaft penetrates through the compression roller and is rotatably arranged at the bottom of the connecting beam, and the roller shaft is in transmission connection with the driving system through a transmission assembly.
Optionally, the transmission assembly includes a first output wheel, a second input wheel, a first gear, a second gear and a synchronizing shaft; the first output wheel is connected with the driving system; the synchronous shaft penetrates through the inner side of the conveying belt and is parallel to the press roller; the two ends of the synchronous shaft are respectively provided with the first gear, and the second gear is arranged at the two ends of the roller shaft and meshed with the first gear; the second inlet and outlet wheel is arranged at one end of the synchronizing shaft and is in transmission connection with the first output wheel.
Optionally, the driving system includes a first driving motor and a second driving motor, the first driving motor is used for driving the dicing system, and the second driving motor is used for driving the conveying system.
Compared with the prior art, the invention has the following technical effects:
the invention discloses an umbilical cord tissue dicer for culturing mesenchymal stem cells, which mainly comprises a main frame, a dicer system, a conveying system and a cutter headA drive system; the driving system respectively drives the cutting system and the conveying system; wherein, conveying system can carry out step-by-step transport to the umbilical cord tissue, makes the transport distance of umbilical cord tissue every time the same, and the stripping and slicing system cuts into 1mm to umbilical cord tissue when carrying the clearance2The small tissue blocks ensure the consistency and uniformity of the thickness, width and length of the cutting blocks.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a schematic structural diagram of an umbilical cord tissue dicer for mesenchymal stem cell culture according to the present invention;
FIG. 2 is a schematic diagram of the main structure of the umbilical cord tissue dicer for mesenchymal stem cell culture according to the present invention;
FIG. 3 is a schematic structural diagram of another perspective of the main structure of the umbilical cord tissue dicer for mesenchymal stem cell culture according to the present invention;
FIG. 4 is a schematic structural diagram of a cutting system in the umbilical cord tissue dicer for mesenchymal stem cell culture according to the present invention;
FIG. 5 is a schematic structural diagram of a conveying system in the mesenchymal stem cell culture umbilical cord tissue dicer of the present invention.
Description of reference numerals: 01. a delivery system; 02. a dicing system; 03. a main frame; 04. a distribution box; 05. a control cabinet;
1. a tool holder; 2. a guide rail; 3. a cross beam; 4. a cutter; 5. a second link; 6. a first link; 7. a main shaft; 8. an eccentric wheel assembly; 9. balancing weight; 10. a belt pulley;
11. a boom; 12. a screw; 13. a hanger; 14. a guide bar; 15. a gantry; 16. a conveyor belt; 17. a compression roller; 18. a roller frame; 19. and (5) connecting the beams.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1 to 5, the present embodiment provides a mesenchymal stem cell culture umbilical cord tissue dicer, which comprises a main frame 03, a dicer system 02, a conveying system 01 and a driving system; the dicing system 02 and the conveying system 01 are both arranged at the top of the main frame 03, and the dicing system 02 is arranged on one side of the conveying system 01; the driving system is used for respectively driving the cutting system 02 and the conveying system 01.
In this embodiment, a gantry 15 is disposed on the top of the main frame 03, and the dicing system 02 and the conveying system 01 are both disposed in the gantry 15.
The driving system comprises a first driving motor and a second driving motor, the first driving motor is used for driving the dicing system 02, and the second driving motor is used for driving the conveying system 01. Wherein, the second motor adopts a stepping motor.
The dicing system 02 comprises a guide mechanism, a cutter 4 and a first transmission mechanism; the guide mechanism comprises a guide rail 2, a sliding block, a cross beam 3 and a tool rest 1; connecting blocks are welded at the positions, close to the doorposts, of the two sides in the door frame 15, and the guide rails 2 are fixed on the connecting blocks through bolts; the sliding blocks are slidably arranged on the guide rails 2, and two ends of the cross beam 3 are respectively connected with the corresponding sliding blocks through bolts; the knife rest 1 is arranged in the middle of the cross beam 3, and the cutter 4 is arranged on the knife rest 1.
The first transmission mechanism is arranged between the guide mechanism and the first motor. Specifically, the first transmission mechanism comprises a main shaft 7, an eccentric wheel assembly 8, a balance weight 9, a first connecting rod 6 and a second connecting rod 5; the main shaft 7 is in transmission connection with the first motor through a synchronous belt; the eccentric wheel assembly 8 and the balance weight 9 are both arranged on the main shaft 7; one end of the first connecting rod 6 is connected with the top of the eccentric wheel assembly 8, the other end of the first connecting rod 6 is rotatably connected with one end of the second connecting rod 5, and the other end of the second connecting rod 5 is connected with the guide mechanism. In a more specific embodiment, the first connecting rod 6 further comprises an upper rod and a lower rod, wherein the lower end of the lower rod is connected with the eccentric wheel assembly 8, the upper end of the upper rod is connected with the bottom of the second connecting rod 5, a threaded rod is fixedly arranged at the top of the lower rod, the top of the threaded rod is in threaded connection with the bottom of the upper rod, a fastening nut is arranged on the threaded rod, the fastening nut is screwed to the bottom of the upper rod to adjust the distance between the upper rod and the lower rod, the purpose of adjusting the total length of the first connecting rod 6 is achieved, and the height of the cutter 4 is further changed.
The eccentric wheel assembly 8 comprises a wheel body, a wheel sleeve and a bearing; the wheel body is of a cylindrical structure, the wheel body is connected with the main shaft 7 in a welding mode, the axis of the wheel body is parallel to the axis of the main shaft 7 but not arranged in a collinear mode, and the wheel sleeve is of a circular structure; the bearing is arranged between the outer wall of the wheel body and the inner wall of the wheel sleeve. The bottom end of the first connecting rod 6 is connected with the top of the outer side wall of the wheel sleeve. More specifically, the eccentric wheel assembly 8 further comprises a side plate, the side plate is an annular plate, a through hole is formed in the middle of the side plate, the diameter of the through hole is larger than the outer diameter of the wheel body, and the outer diameter of the side plate is equal to the outer diameter of the wheel sleeve; the side plates are arranged on two sides of the wheel body and connected with the side walls of the wheel sleeve through a plurality of bolts, the axial position of the bearing is limited through the side plates, and the bearing is convenient to replace and maintain.
The conveying system 01 comprises a conveying belt 16, a press roller 17, a pressure adjusting structure and a second transmission mechanism; the conveying belt 16 is arranged below the compression roller 17, and the compression roller 17 is arranged in the middle of the bottom of the pressure adjusting structure; the conveying belt 16 and the press roller 17 are in transmission connection with the driving system through the second transmission mechanism respectively.
The pressure adjusting structure comprises a screw 12, a suspension rod 11, a hanging bracket 13, a guide rod 14, a connecting beam 19 and a roller frame 18; the screw 12 is arranged at the position close to two sides of the top of the gantry 15 along the vertical direction, and the suspension rod 11 is arranged on the screw 12 through an adjusting nut; the hanger 13 is arranged right below the boom 11, and the bottom of the hanger 13 is connected with the main frame 03 in a sliding manner through a guide rod 14; an elastic part is arranged between the suspension rod 11 and the hanger 13, and the elastic part is preferably a spiral spring; the end part of the connecting beam 19 is fixedly connected with the guide rod 14, the roller frame 18 is arranged in the middle of the connecting beam 19, and the press roller 17 is arranged at the lower part of the roller frame 18. Adjusting nuts are arranged on the upper side and the lower side of the suspender 11, the height of the suspender 11 is changed by changing the positions of the adjusting nuts on the screw rods 12, and then the pretightening force of the spiral spring is changed, so that the technical effect of changing the maximum output pressure of the compression roller 17 is achieved.
The top of the roller frame 18 is provided with a long round hole, the connecting beam 19 is provided with a threaded hole, and the roller frame 18 and the connecting beam 19 are connected by inserting a bolt into the long round hole and the threaded hole; the roller frame 18 and the cutter 4 are arranged at a first interval, and the first interval is adjusted by adjusting the position of the long round hole on the roller frame 18 relative to the threaded hole on the connecting beam 19, so that the cutter 4 can conveniently cut umbilical cord tissues.
The second transmission mechanism comprises a roll shaft; the roll shaft penetrates through the press roll 17 and is rotatably arranged at the bottom of the connecting beam 19, and the roll shaft is in transmission connection with the driving system through a transmission assembly.
The transmission assembly comprises a first output wheel, a second input wheel, a second gear, a first gear and a second gear and a synchronous shaft; the first output wheel is connected with the driving system; the synchronous shaft penetrates through the inner side of the conveying belt 16 and is parallel to the press roller 17; the two ends of the synchronous shaft are respectively provided with the first gear, and the second gear is arranged at the two ends of the roller shaft and meshed with the first gear; the second inlet and outlet wheel is arranged at one end of the synchronizing shaft and is in transmission connection with the first output wheel. The first output wheel and the second input and output wheel both adopt chain wheels.
The umbilical cord tissue dicer for mesenchymal stem cell culture further comprises a control system, wherein the control system is electrically connected with the driving system and is used for controlling the output of the driving system. The step distance of the second motor can be set by the control system to vary the slice volume.
The control system further comprises a sensor, the sensor is arranged on one side, facing the cutter 4, of the middle of the door frame 15 and used for monitoring the working state of the cutter 4, specifically, when the cutter 4 moves upwards to the highest point accessory, the sensor senses the existence of the cutter 4, and when the cutter 4 moves to a lower position, the sensor cannot sense the cutter 4; when the equipment is started, the sensor does not detect the existence of the cutter 4 for a long time or detects that the cutter 4 exists all the time, and the equipment is stopped. The sensor is a proximity induction sensor.
When the umbilical cord cutting machine is used, the equipment is started, the cutting thickness is set through the control system, a section of umbilical cord with the required length is cut, the umbilical cord tissue is placed on the supporting plate, the supporting plate bearing the umbilical cord tissue is placed on the conveying belt 16, and the umbilical cord tissue moves forwards along the conveying belt 16 under the synchronous stepping conveying of the conveying belt 16 and the pressing roller 17; the cutter 4 is driven by the first motor to reciprocate up and down along the guide rail 2; when the umbilical cord tissue is conveyed below the cutter 4, the umbilical cord tissue is cut into pieces by the cutter 4; the pallet carrying the umbilical cord tissue is rotated 90 degrees and then placed on the conveyer belt 16 again, and the sheet umbilical cord tissue is cut into pieces.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein, and any reference signs in the claims are not intended to be construed as limiting the claim concerned.
The principle and the implementation mode of the present invention are explained by applying specific examples in the present specification, and the above descriptions of the examples are only used to help understanding the method and the core idea of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In view of the above, the present disclosure should not be construed as limiting the invention.

Claims (10)

1. An umbilical cord tissue dicer for culturing mesenchymal stem cells is characterized by comprising a main frame, a dicer system, a conveying system and a driving system; the dicing system and the conveying system are both arranged at the top of the main frame, and the dicing system is arranged on one side of the conveying system; the driving system is used for respectively driving the dicing system and the conveying system.
2. The mesenchymal stem cell culture umbilical cord tissue dicer of claim 1, further comprising a control system, the control system being electrically connected to the drive system, the control system being configured to control an output of the drive system.
3. The umbilical cord tissue dicer for mesenchymal stem cell culture according to claim 1, wherein the dicer system comprises a guide mechanism, a cutter and a first transmission mechanism; the cutter is arranged on the guide mechanism, and the first transmission mechanism is arranged between the guide mechanism and the driving system.
4. The umbilical cord tissue dicer for mesenchymal stem cell culture according to claim 3, wherein the guide mechanism comprises a guide rail, a slide block, a cross beam and a knife rest; the guide rail is fixedly connected with the main frame; the sliding block is arranged on the guide rail in a sliding manner, and the end part of the beam is connected with the sliding block; the knife rest is arranged in the middle of the cross beam, and the cutter is arranged on the knife rest.
5. The mesenchymal stem cell culture umbilical cord tissue dicer of claim 3, wherein the first transmission mechanism comprises a main shaft, an eccentric wheel assembly, a counterweight, a first connecting rod and a second connecting rod; the main shaft is in transmission connection with the driving system; the eccentric wheel assembly and the balance weight are both arranged on the main shaft; one end of the first connecting rod is connected with the top of the eccentric wheel assembly, the other end of the first connecting rod is rotatably connected with one end of the second connecting rod, and the other end of the second connecting rod is connected with the guide mechanism.
6. The umbilical cord tissue dicer for mesenchymal stem cell culture according to claim 1, wherein the conveying system comprises a conveyer belt, a press roller, a pressure regulating structure and a second transmission mechanism; the conveying belt is arranged below the compression roller, and the compression roller is arranged in the middle of the bottom of the pressure adjusting structure; the conveying belt and the press roller are in transmission connection with the driving system through the second transmission mechanism respectively.
7. The umbilical cord tissue dicer for mesenchymal stem cell culture according to claim 6, wherein the pressure regulating structure comprises a screw, a suspension rod, a hanger, a guide rod, a coupling beam and a roller frame; the screw rod is arranged at the top of the main frame along the vertical direction, and the hanging rod is arranged on the screw rod through an adjusting nut; the hanger is arranged right below the suspender, and the bottom of the hanger is in sliding connection with the main rack through a guide rod; an elastic part is arranged between the hanging rod and the hanging bracket; the end part of the connecting beam is fixedly connected with the guide rod, the roller frame is arranged in the middle of the connecting beam, and the press roller is arranged on the lower part of the roller frame.
8. The mesenchymal stem cell culture umbilical cord tissue dicer of claim 6, wherein the second transmission mechanism comprises a roller shaft; the roller shaft penetrates through the compression roller and is rotatably arranged at the bottom of the connecting beam, and the roller shaft is in transmission connection with the driving system through a transmission assembly.
9. The mesenchymal stem cell culture umbilical cord tissue dicer of claim 8, wherein the transmission assembly comprises a first output wheel, a second input and output wheel, a first gear, a second gear and a synchronizing shaft; the first output wheel is connected with the driving system; the synchronous shaft penetrates through the inner side of the conveying belt and is parallel to the press roller; the two ends of the synchronous shaft are respectively provided with the first gear, and the second gear is arranged at the two ends of the roller shaft and meshed with the first gear; the second inlet and outlet wheel is arranged at one end of the synchronizing shaft and is in transmission connection with the first output wheel.
10. The mesenchymal stem cell culture umbilical cord tissue dicer of claim 1, wherein the drive system comprises a first drive motor for driving the dicer system and a second drive motor for driving the conveyor system.
CN202110824343.XA 2021-07-21 2021-07-21 Mesenchymal stem cell culture umbilical cord tissue dicer Withdrawn CN113427545A (en)

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Application Number Priority Date Filing Date Title
CN202110824343.XA CN113427545A (en) 2021-07-21 2021-07-21 Mesenchymal stem cell culture umbilical cord tissue dicer

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Application Number Priority Date Filing Date Title
CN202110824343.XA CN113427545A (en) 2021-07-21 2021-07-21 Mesenchymal stem cell culture umbilical cord tissue dicer

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CN113427545A true CN113427545A (en) 2021-09-24

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CN202110824343.XA Withdrawn CN113427545A (en) 2021-07-21 2021-07-21 Mesenchymal stem cell culture umbilical cord tissue dicer

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113967931A (en) * 2021-10-20 2022-01-25 张斌 Umbilical cord tissue cutting machine
CN115804856A (en) * 2023-02-08 2023-03-17 天津长和生物技术有限公司 Instrument degassing unit after umbilical cord tissue cutting

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113967931A (en) * 2021-10-20 2022-01-25 张斌 Umbilical cord tissue cutting machine
CN115804856A (en) * 2023-02-08 2023-03-17 天津长和生物技术有限公司 Instrument degassing unit after umbilical cord tissue cutting

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Application publication date: 20210924