CN113425704A - Medical cold compress patch capable of accelerating wound healing - Google Patents

Medical cold compress patch capable of accelerating wound healing Download PDF

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Publication number
CN113425704A
CN113425704A CN202110695432.9A CN202110695432A CN113425704A CN 113425704 A CN113425704 A CN 113425704A CN 202110695432 A CN202110695432 A CN 202110695432A CN 113425704 A CN113425704 A CN 113425704A
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China
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layer
cold compress
parts
medical cold
waterproof ring
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Inventor
吉晨
王保镇
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Jiangsu Yi Ren Tang Biotechnology Co ltd
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Jiangsu Yi Ren Tang Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F2007/0225Compresses or poultices for effecting heating or cooling connected to the body or a part thereof
    • A61F2007/0226Compresses or poultices for effecting heating or cooling connected to the body or a part thereof adhesive, self-sticking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F2007/0261Compresses or poultices for effecting heating or cooling medicated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F2007/0261Compresses or poultices for effecting heating or cooling medicated
    • A61F2007/0263Compresses or poultices for effecting heating or cooling medicated made of a substance with therapeutic action, e.g. copper or silver
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F2007/0292Compresses or poultices for effecting heating or cooling using latent heat produced or absorbed during phase change of materials, e.g. of super-cooled solutions
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention discloses a medical cold compress patch capable of accelerating wound healing, which comprises a medical cold compress patch body and a cold compress extracting solution, wherein the medical cold compress patch body comprises a surface layer, a waterproof ring, an adsorption filling layer and an anti-sticking layer, the waterproof ring is bonded at the center of the upper surface of the surface layer, and the cold compress extracting solution is adsorbed inside the adsorption filling layer; according to the medical cold compress patch, a cold compress extracting solution is prepared from Chinese gall, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, mint leaf, rosewood heart wood, red paeony root, pomegranate rind, glycerol and deionized water, the cold compress extracting solution is adsorbed by the adsorption filling layer, the adsorption filling layer is surrounded by the waterproof ring, the cold compress extracting solution absorbed by the adsorption filling layer is prevented from leaking out, then the medical cold compress patch is attached to a wound, the effect of cold compress pain relief is achieved, and the healing of the wound can be accelerated by matching the Chinese gall, bloody scorpion, wild fire rope, giant knotweed rhizome and common threewingnut root.

Description

Medical cold compress patch capable of accelerating wound healing
Technical Field
The invention relates to the technical field of medical cold compress patches, in particular to a medical cold compress patch capable of accelerating wound healing.
Background
The medical cold patch can contract local capillary vessels, relieve local congestion, reduce sensitivity of nerve endings to relieve pain, reduce temperature and defervesce, reduce local blood flow, and prevent inflammation and suppuration and diffusion.
The principle of the medical cold compress patch is simple, namely heat is taken away according to the vaporization of water and natural cooling components contained in the product, so that the effect of local cooling can be achieved, and the medicine can rapidly penetrate through a fat layer through the medicine components after hydrogel is combined, and then permeates into subcutaneous tissues to directly reach focuses, so that the effects and effects of cold compress pain relief, percutaneous absorption and sustained release administration are achieved.
When skin has a wound, in order to play a role in relieving pain, a medical cold compress patch can be attached to the wound, and although the existing medical cold compress patch can play a role in dispelling pain through cold compress, the healing of the wound cannot be accelerated, so that the medical cold compress patch capable of accelerating the healing of the wound is needed.
Disclosure of Invention
The invention aims to provide a medical cold compress patch capable of accelerating wound healing so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: the medical cold compress patch capable of accelerating wound healing comprises a medical cold compress patch body and a cold compress extracting solution, wherein the medical cold compress patch body comprises a surface layer, a waterproof ring, an adsorption filling layer and an anti-sticking layer, the waterproof ring is bonded at the center of the upper surface of the surface layer, the adsorption filling layer is filled in the waterproof ring, the anti-sticking layer is bonded on the upper surface of the surface layer, the waterproof ring and the adsorption filling layer are located between the anti-sticking layer and the surface layer, and the cold compress extracting solution is adsorbed in the adsorption filling layer.
The cold compress extracting solution comprises the following components in parts by weight: 25-30 parts of gallnut, 20-25 parts of scorpion, 20-25 parts of wild fire rope, 20-25 parts of giant knotweed, 10-15 parts of tripterygium wilfordii, 10-15 parts of mint leaf, 10-15 parts of dalbergia wood, 10-15 parts of red paeony root, 10-15 parts of pomegranate peel, 40-45 parts of glycerol and the balance of deionized water.
The preparation method of the cold compress extracting solution comprises the following steps:
step one, weighing gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind according to weight, then sequentially adding the weighed gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind into a reaction kettle, and stirring 10-15 parts by the reaction kettle to uniformly mix the gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind together;
step two, adding deionized water which is 10-15 times of the total weight of the raw materials into a reaction kettle, then adjusting the temperature of the reaction kettle to 850-950 ℃, and using the reaction kettle to decoct for 4-5 hours at high temperature;
regulating the temperature of the reaction kettle to 550-650 ℃, continuously using the reaction kettle for high-temperature decoction for 2-3 hours, standing for 1-2 hours at normal temperature, taking out and filtering to obtain a mixed solution;
and step four, adding the mixed solution obtained by filtering into a reaction kettle, then weighing glycerol according to the weight parts, adding the weighed glycerol into the reaction kettle, stirring for 15-20 minutes through the reaction kettle, taking out and sterilizing to obtain the cold compress extracting solution.
The surface layer is made of non-woven fabrics, and an adhesive layer is coated on one side, surrounding the waterproof ring, of the surface layer surface.
The waterproof ring is made of a silica gel ring, the adsorption filling layer is made of medical sponge, and the height dimension of the adsorption filling layer is larger than that of the waterproof ring.
Wherein, antiseized layer adopts to make from type paper, antiseized layer lower surface is provided with the cooperation the barrier layer of waterproof circle, the barrier layer is the integral type structure with antiseized layer, the barrier layer adopts to make from type paper.
Wherein the diameter size of the barrier layer is the same as the outer diameter size of the waterproof ring surface.
The preparation method of the medical cold compress patch comprises the following steps:
s1, soaking the adsorption filling layer in the cold compress extracting solution by 5-10 parts, and then plugging the adsorption filling layer adsorbed with the cold compress extracting solution into the waterproof ring;
s2, adhering an anti-sticking layer to the surface of the surface layer through an adhesive layer, covering the waterproof ring and the adsorption filling layer through the anti-sticking layer, and aligning the barrier layer with the waterproof ring and the adsorption filling layer to obtain the medical cold compress patch;
and S3, when the medical cold compress patch is needed to be used, the anti-sticking layer is torn, the absorption filling layer is aligned to the wound position of a user, and the medical cold compress patch is attached to the wound of the user through the adhesive layer.
Compared with the prior art, the invention has the beneficial effects that:
according to the medical cold compress patch, a cold compress extracting solution is prepared from Chinese gall, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, mint leaf, rosewood heart wood, red paeony root, pomegranate rind, glycerol and deionized water, the cold compress extracting solution is adsorbed by the adsorption filling layer, the adsorption filling layer is surrounded by the waterproof ring, the cold compress extracting solution absorbed by the adsorption filling layer is prevented from leaking out, then the medical cold compress patch is attached to a wound, the effect of cold compress pain relief is achieved, and the healing of the wound can be accelerated by matching the Chinese gall, bloody scorpion, wild fire rope, giant knotweed rhizome and common threewingnut root.
Drawings
FIG. 1 is a schematic overall front view of the present invention;
FIG. 2 is a front view of the surface layer of the present invention;
FIG. 3 is a schematic bottom view of the release layer of the present invention.
In FIGS. 1-3: 10. a surface layer; 11. an adhesive layer; 20. a waterproof ring; 30. an adsorption filling layer; 40. an anti-sticking layer; 41. and a barrier layer.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In an embodiment, referring to fig. 1-3, the present invention provides a technical solution: the utility model provides a can accelerate medical cold application of wound healing, including medical cold application body and cold compress extract, the body is pasted including superficial layer 10 to medical cold application, waterproof circle 20, absorption filling layer 30 and antiseized layer 40, the center department of superficial layer 10 upper surface bonds and has waterproof circle 20, waterproof circle 20 inside packing has absorption filling layer 30, superficial layer 10 upper surface bonds and has antiseized layer 40, waterproof circle 20 is located between antiseized layer 40 and superficial layer 10 with absorption filling layer 30, the inside absorption of absorption filling layer 30 has the cold compress extract.
The cold compress extracting solution comprises the following components in parts by weight: 26 parts of gallnut, 22 parts of scorpion, 22 parts of wild fire rope, 22 parts of giant knotweed rhizome, 13 parts of common threewingnut root, 13 parts of mint leaf, 13 parts of dalbergia wood, 13 parts of red paeony root, 13 parts of pomegranate bark, 42 parts of glycerol and the balance of deionized water.
The preparation method of the cold compress extracting solution comprises the following steps:
step one, weighing gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind according to weight, then sequentially adding the weighed gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind into a reaction kettle, and stirring 10-15 parts by the reaction kettle to uniformly mix the gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind together;
step two, adding deionized water which is 10-15 times of the total weight of the raw materials into a reaction kettle, then adjusting the temperature of the reaction kettle to 850-950 ℃, and using the reaction kettle to decoct for 4-5 hours at high temperature;
regulating the temperature of the reaction kettle to 550-650 ℃, continuously using the reaction kettle for high-temperature decoction for 2-3 hours, standing for 1-2 hours at normal temperature, taking out and filtering to obtain a mixed solution;
and step four, adding the mixed solution obtained by filtering into a reaction kettle, then weighing glycerol according to the weight parts, adding the weighed glycerol into the reaction kettle, stirring for 15-20 minutes through the reaction kettle, taking out and sterilizing to obtain the cold compress extracting solution.
Wherein, the surface layer 10 is made of non-woven fabrics, and one side of the surface layer 10 surrounding the waterproof ring 20 is coated with an adhesive layer 11.
Wherein, waterproof circle 20 adopts the silica gel circle to make, and absorption filling layer 30 adopts medical sponge to make, and the height dimension of absorption filling layer 30 is greater than waterproof circle 20.
Wherein, antiseized layer 40 adopts to make from type paper, and antiseized layer 40 lower surface is provided with the barrier layer 41 of the waterproof circle 20 of cooperation, and barrier layer 41 is the integral type structure with antiseized layer 40, and barrier layer 41 adopts to make from type paper.
The diameter of the barrier layer 41 is the same as the outer diameter of the surface of the waterproof ring 20.
The preparation method of the medical cold compress patch comprises the following steps:
s1, soaking the adsorption filling layer in the cold compress extracting solution by 5-10 parts, and then plugging the adsorption filling layer adsorbed with the cold compress extracting solution into the waterproof ring;
s2, adhering an anti-sticking layer to the surface of the surface layer through an adhesive layer, covering the waterproof ring and the adsorption filling layer through the anti-sticking layer, and aligning the barrier layer with the waterproof ring and the adsorption filling layer to obtain the medical cold compress patch;
and S3, when the medical cold compress patch is needed to be used, the anti-sticking layer is torn, the absorption filling layer is aligned to the wound position of a user, and the medical cold compress patch is attached to the wound of the user through the adhesive layer.
Experimental example, wound healing cycle test;
selecting samples, selecting 10 mice with the same growth cycle, the same body type and the same weight, and drawing a 0.8cm wound at the same position of the front left leg of each mouse by using a scalpel;
preparing experimental groups, namely selecting 5 medical cold compress patches prepared in the embodiments and marking the medical cold compress patches as group A medical cold compress patches;
preparing a comparison group, namely selecting common medical cold compress gel on the market to replace the cold compress extracting solution prepared by the invention, adsorbing the selected medical cold compress gel into an adsorption filling layer, and preparing 5 medical cold compress patches containing the medical cold compress gel, wherein the medical cold compress patches are marked as group B medical cold compress patches;
according to the experimental method, the medical cold compress plasters of the group A are attached to the wounds of the legs of the selected 5 mice, the medical cold compress plasters of the group B are attached to the wounds of the legs of the other 5 selected mice, the mice are tracked and observed, and the result records are shown in the following table:
Figure 1
as can be seen from the above table, the adsorption filling layer adsorbs the cold compress extracting solution prepared by the invention, and then the medical cold compress patch containing the cold compress extracting solution is attached to the wound of the leg of the white rat, so that the scabbing speed of the leg wound of the white rat is increased, and the healing speed of the leg wound of the white rat is also increased.
To sum up, prepare the cold compress extract through gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, threewingnut root, peppermint leaf, dalbergia wood, red peony root, pomegranate rind, glycerine and deionized water to adsorb this cold compress extract through the adsorption filling layer, surround the adsorption filling layer through waterproof circle simultaneously, avoid the inside absorptive cold compress extract of adsorption filling layer to leak out, then with this medical cold compress paste attached in the wound, not only have the effect that the cold compress is dispelled the pain, can accelerate the healing of wound through gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome and the cooperation of thunder god vine.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. The utility model provides a can accelerate wound healing's medical cold compress paste, includes medical cold compress paste body and cold compress extract, its characterized in that: the medical cold compress body comprises a surface layer (10), a waterproof ring (20), an adsorption filling layer (30) and an anti-sticking layer (40), wherein the waterproof ring (20) is bonded at the center of the upper surface of the surface layer (10), the adsorption filling layer (30) is filled in the waterproof ring (20), the anti-sticking layer (40) is bonded on the upper surface of the surface layer (10), the waterproof ring (20) and the adsorption filling layer (30) are positioned between the anti-sticking layer (40) and the surface layer (10), and a cold compress extracting solution is adsorbed in the adsorption filling layer (30);
the cold compress extracting solution comprises the following components in parts by weight: 25-30 parts of gallnut, 20-25 parts of scorpion, 20-25 parts of wild fire rope, 20-25 parts of giant knotweed, 10-15 parts of tripterygium wilfordii, 10-15 parts of mint leaf, 10-15 parts of dalbergia wood, 10-15 parts of red paeony root, 10-15 parts of pomegranate peel, 40-45 parts of glycerol and the balance of deionized water.
2. The medical cold patch capable of accelerating wound healing according to claim 1, wherein: the preparation method of the cold compress extracting solution comprises the following steps:
step one, weighing gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind according to weight, then sequentially adding the weighed gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind into a reaction kettle, and stirring 10-15 parts by the reaction kettle to uniformly mix the gallnut, bloody scorpion, wild fire rope, giant knotweed rhizome, common threewingnut root, peppermint leaf, dalbergia wood, red paeony root and pomegranate rind together;
step two, adding deionized water which is 10-15 times of the total weight of the raw materials into a reaction kettle, then adjusting the temperature of the reaction kettle to 850-950 ℃, and using the reaction kettle to decoct for 4-5 hours at high temperature;
regulating the temperature of the reaction kettle to 550-650 ℃, continuously using the reaction kettle for high-temperature decoction for 2-3 hours, standing for 1-2 hours at normal temperature, taking out and filtering to obtain a mixed solution;
and step four, adding the mixed solution obtained by filtering into a reaction kettle, then weighing glycerol according to the weight parts, adding the weighed glycerol into the reaction kettle, stirring for 15-20 minutes through the reaction kettle, taking out and sterilizing to obtain the cold compress extracting solution.
3. The medical cold patch capable of accelerating wound healing according to claim 2, wherein: the surface layer (10) is made of non-woven fabrics, and one side, surrounding the waterproof ring (20), of the surface layer (10) is coated with an adhesive layer (11).
4. The medical cold patch capable of accelerating wound healing according to claim 3, wherein: the waterproof ring (20) is made of a silica gel ring, the adsorption filling layer (30) is made of medical sponge, and the height of the adsorption filling layer (30) is larger than that of the waterproof ring (20).
5. The medical cold patch capable of accelerating wound healing according to claim 4, wherein: antiseized layer (40) adopt to make from type paper, antiseized layer (40) lower surface is provided with the cooperation barrier layer (41) of waterproof circle (20), barrier layer (41) are the integral type structure with antiseized layer (40), barrier layer (41) adopt to make from type paper.
6. The medical cold patch capable of accelerating wound healing according to claim 5, wherein: the diameter size of the barrier layer (41) is the same as the outer diameter size of the surface of the waterproof ring (20).
7. The medical cold patch capable of accelerating wound healing according to claim 6, wherein: the preparation method of the medical cold compress patch comprises the following steps:
s1, soaking the adsorption filling layer in the cold compress extracting solution by 5-10 parts, and then plugging the adsorption filling layer adsorbed with the cold compress extracting solution into the waterproof ring;
s2, adhering an anti-sticking layer to the surface of the surface layer through an adhesive layer, covering the waterproof ring and the adsorption filling layer through the anti-sticking layer, and aligning the barrier layer with the waterproof ring and the adsorption filling layer to obtain the medical cold compress patch;
and S3, when the medical cold compress patch is needed to be used, the anti-sticking layer is torn, the absorption filling layer is aligned to the wound position of a user, and the medical cold compress patch is attached to the wound of the user through the adhesive layer.
CN202110695432.9A 2021-06-23 2021-06-23 Medical cold compress patch capable of accelerating wound healing Pending CN113425704A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN206675631U (en) * 2016-10-21 2017-11-28 山东华悦生物科技有限公司 Medical cold applies
CN210903624U (en) * 2019-07-29 2020-07-03 江苏益仁堂生物科技有限公司 Medical cold compress patch with good defervescence and ventilation effect
CN111437207A (en) * 2020-05-08 2020-07-24 广州市泫享生物科技有限公司 Application type beauty treatment patch with permeation function and preparation method thereof
CN213130295U (en) * 2020-07-30 2021-05-07 浙江红雨医药用品有限公司 Band-aid with strong antibacterial and waterproof properties

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN206675631U (en) * 2016-10-21 2017-11-28 山东华悦生物科技有限公司 Medical cold applies
CN210903624U (en) * 2019-07-29 2020-07-03 江苏益仁堂生物科技有限公司 Medical cold compress patch with good defervescence and ventilation effect
CN111437207A (en) * 2020-05-08 2020-07-24 广州市泫享生物科技有限公司 Application type beauty treatment patch with permeation function and preparation method thereof
CN213130295U (en) * 2020-07-30 2021-05-07 浙江红雨医药用品有限公司 Band-aid with strong antibacterial and waterproof properties

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