CN113402518B - 含有取代的胍基团的咪唑并[4,5-c]环化合物 - Google Patents

含有取代的胍基团的咪唑并[4,5-c]环化合物 Download PDF

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Publication number
CN113402518B
CN113402518B CN202110672923.1A CN202110672923A CN113402518B CN 113402518 B CN113402518 B CN 113402518B CN 202110672923 A CN202110672923 A CN 202110672923A CN 113402518 B CN113402518 B CN 113402518B
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alkyl
salt
compound
hydrogen
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CN113402518A (zh
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乔治·W·格里斯格拉伯
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Shuwanuo Intellectual Property Co
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3M Innovative Properties Co
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN202110672923.1A 2015-08-31 2016-08-26 含有取代的胍基团的咪唑并[4,5-c]环化合物 Expired - Fee Related CN113402518B (zh)

Priority Applications (1)

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CN202110672923.1A CN113402518B (zh) 2015-08-31 2016-08-26 含有取代的胍基团的咪唑并[4,5-c]环化合物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562211896P 2015-08-31 2015-08-31
US62/211,896 2015-08-31
CN201680049829.8A CN107922416B (zh) 2015-08-31 2016-08-26 含有取代的胍基团的咪唑并[4,5-c]环化合物
PCT/US2016/048831 WO2017040234A1 (en) 2015-08-31 2016-08-26 IMIDAZO[4,5-c] RING COMPOUNDS CONTAINING SUBSTITUTED GUANIDINE GROUPS
CN202110672923.1A CN113402518B (zh) 2015-08-31 2016-08-26 含有取代的胍基团的咪唑并[4,5-c]环化合物

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CN113402518A CN113402518A (zh) 2021-09-17
CN113402518B true CN113402518B (zh) 2023-08-22

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CN201680049829.8A Active CN107922416B (zh) 2015-08-31 2016-08-26 含有取代的胍基团的咪唑并[4,5-c]环化合物

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US (1) US10118925B2 (enExample)
EP (1) EP3344623B1 (enExample)
JP (1) JP6956071B2 (enExample)
CN (2) CN113402518B (enExample)
WO (1) WO2017040234A1 (enExample)

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KR102685007B1 (ko) 2015-08-31 2024-07-12 쓰리엠 이노베이티브 프로퍼티즈 컴파니 구아니딘 치환된 이미다조[4,5-c] 고리 화합물
BR112019000071A2 (pt) 2016-07-07 2019-07-02 Bolt Biotherapeutics Inc conjugados adjuvantes de anticorpo
EP3504215B1 (en) 2016-08-26 2022-04-06 3M Innovative Properties Company Fused [1,2]imidazo[4,5-c]ring compounds substituted with guanidino groups
US10766896B2 (en) 2017-03-01 2020-09-08 3M Innovative Properties Company Imidazo[4,5-c] ring compounds containing guanidine substituted benzamide groups
EP3887369B1 (en) * 2018-11-26 2024-05-08 Solventum Intellectual Properties Company N-1 branched alkyl ether substituted imidazo[4,5-c]quinoline compounds, compositions, and methods
EP3937984A1 (en) 2019-03-15 2022-01-19 Bolt Biotherapeutics, Inc. Immunoconjugates targeting her2

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UA67760C2 (uk) 1997-12-11 2004-07-15 Міннесота Майнінг Енд Мануфакчурінг Компані Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
US6110929A (en) 1998-07-28 2000-08-29 3M Innovative Properties Company Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
US6573273B1 (en) 1999-06-10 2003-06-03 3M Innovative Properties Company Urea substituted imidazoquinolines
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Also Published As

Publication number Publication date
US10118925B2 (en) 2018-11-06
CN113402518A (zh) 2021-09-17
EP3344623A1 (en) 2018-07-11
WO2017040234A1 (en) 2017-03-09
JP6956071B2 (ja) 2021-10-27
EP3344623B1 (en) 2021-02-17
US20180244669A1 (en) 2018-08-30
JP2018525427A (ja) 2018-09-06
CN107922416B (zh) 2021-07-02
CN107922416A (zh) 2018-04-17

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