CN113398194B - Traditional Chinese medicine composition for soothing nerves and aiding sleep and U-shaped inhalant - Google Patents

Traditional Chinese medicine composition for soothing nerves and aiding sleep and U-shaped inhalant Download PDF

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CN113398194B
CN113398194B CN202110871066.8A CN202110871066A CN113398194B CN 113398194 B CN113398194 B CN 113398194B CN 202110871066 A CN202110871066 A CN 202110871066A CN 113398194 B CN113398194 B CN 113398194B
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soothing
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nerves
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CN113398194A (en
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赵玉华
李陈渝
高洁
唐军
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Chongqing Traditional Chinese Medicine Hospital
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Abstract

The application provides a traditional Chinese medicine composition for soothing nerves and helping sleep and a U-shaped inhalant, which take dragon bones and oysters as monarch drugs to play a role in calming nerves; caulis Polygoni Multiflori and rhizoma Acori Tatarinowii as ministerial drugs for calming heart, tranquilizing mind, and benefiting mind; the rose, the eupatorium, the fingered citron and the folium artemisiae argyi are used as adjuvant medicines for promoting qi circulation and relieving depression, and nourishing heart and soothing nerves; the mint, the rhizoma atractylodis and the dried orange peel are used as guiding drugs, and the fragrant flavoring agent has the effects of promoting qi circulation, relieving depression, clearing away the heart-fire and soothing the nerves. Long Gu and Shi Chang Pu are combined together to astringe floating qi, improve unsteadiness of heart-mind caused by yin-yang imbalance and strengthen the effect of calming heart and tranquilizing mind. Mu Li and Long Gu are mutually reinforced to strengthen the action of tranquilizing mind, so they are indicated for restlessness of mind, palpitation due to fright, insomnia and dreaminess. The use of caulis Polygoni Multiflori in combination with Os Draconis and Concha Ostreae can improve sleep improving effect. The effective components of the raw material medicines of the traditional Chinese medicine composition can generate low-concentration medicine aerosol in the air, and the medicine aerosol takes effect in vivo through a respiratory tract, so that the effects of soothing the nerves, helping sleep, regulating yin and yang and paralleling qi and blood can be achieved.

Description

Traditional Chinese medicine composition for soothing nerves and aiding sleep and U-shaped inhalant
Technical Field
The application relates to the technical field of insomnia prevention and treatment, and particularly relates to a traditional Chinese medicine composition for soothing nerves and assisting sleep and a U-shaped inhalant.
Background
Insomnia refers to a clinically occurring sleep disorder that is persistent, frequently difficult to fall asleep and/or difficult to maintain sleep, and results in a feeling of dissatisfaction with sleep being a major feature.
Epidemiological investigations have shown that 45.4% of people in china have experienced different degrees of insomnia in the past 1 month, and 10% suffer from insomnia. Among the over 90 sleep disorders covered by the international sleep disorder classification (ICSD-10), insomnia is the most common sleep disorder. In our country, insomnia has become the second largest disease in neurology clinics after headache. With the continuous acceleration of the life rhythm of people and the gradual increase of working pressure, the competition is intensified day by day, and the insomnia people are in a growing situation due to poor living habits such as drinking a large amount and staying up all night.
Insomnia disorders, which are considered by western medicine to be sleep disorders characterized by frequent difficulty in falling asleep or maintaining sleep and resulting in insufficient sleep satisfaction, are often accompanied by confusion or impairment of household, social, occupational, academic, or other important functions.
The traditional Chinese medicine names insomnia, eye insomnia and lying-down, and the traditional Chinese medicine considers that insomnia is located in the heart and closely related to the liver, spleen and kidney. The pathogenesis of the disease is that internal injury of seven emotions, diet disorder, physical weakness and fatigue occur, the pathogenesis is that the nutrition and defense are disordered, yang does not enter yin, yin and yang are not crossed or yin deficiency and yang is hyperactivity, and the pathological changes are generally yin-yang disorder.
The intervention for insomnia mainly comprises the following steps: drug therapy and non-drug therapy.
The medicines for treating insomnia mainly comprise benzodiazepines, non-benzodiazepines, melatonin receptor agonists, anxiolytic and antidepressant medicines and the like, but the medicines have side effects of rebound curative effect, drug dependence, memory impairment, liver and kidney impairment and the like to different degrees. Therefore, the clinical application of the medicine is limited to a certain extent.
Compared with a drug therapy, the non-drug therapy has higher safety, and the behavioral intervention therapy in the non-drug therapy has been applied to a certain extent in clinic, but has higher professional requirements on operation, and also has higher requirements on compliance, degree of self-discipline and degree of coordination for patients, so that the wide-range popularization in clinic still has certain difficulty. Therefore, the search for drug therapies with fewer side effects and greater convenience has become an urgent need in clinical treatment today.
The application of traditional Chinese medicines in a series of diseases such as insomnia and the like has proved to be effective as a treatment method with small side effect and high safety in clinical operation, but the selection and clinical compatibility of the traditional Chinese medicines are different, although years of exploration prove that no standardized scheme exists at present, the synergistic effect can be achieved when the traditional Chinese medicines for soothing the nerves and helping sleep are combined, namely the formula is used for treating the primary insomnia, the clinical curative effect is proved by practical application, but the exact mechanism is not completely clear, and the further deep research is needed.
Aromatherapy is one of the characteristic means of preventing and treating diseases in traditional Chinese medicine. For example, in Puji Fang, the monograph of all herbs is that the experience of aromatherapy is collected and summarized. The compendium of materia medica is a broad-gathering and college, and the record of aromatic drugs is enriched. The famous medical Wu-Shi machine of Qing Dynasty (Ri \28729Zhongo-Wen) has made systematic exposition on the action mechanism, dialectical treatment, medicine selection, usage and dosage, and cautions of aromatic therapy.
The aromatherapy is used as a supplement therapy or a replacement therapy in insomnia treatment, has the characteristics of low risk, low cost, simple operation and low side effect, and a plurality of researches show that the aromatherapy can improve the sleep quality and daytime symptoms of patients in different degrees, relieve psychological symptoms of anxiety, depression, mood and the like of the patients and improve the life quality of the patients.
At home and abroad, modes such as lavender essential oil and mint essential oil inhalation are mostly adopted for aromatherapy, related traditional Chinese medicine research in domestic aromatherapy is not much, common hypnotic products in the market at present comprise instruments, foot bath bags and hypnotic pillows, U inhalation mainly takes carsickness prevention and treatment and refreshing products, a small amount of sleep-assisting U inhalation takes natural plant essential oil as a main material, and no traditional Chinese medicine formula material exists.
The traditional Chinese medicine contains partial Chinese medicines with the effects of fragrance and tranquilization, is convenient to obtain materials, safe and effective, and aims to find a substitute treatment mode which is easy to accept, simple to operate, safe and low in price for insomnia people.
Disclosure of Invention
The embodiment of the application aims to provide the traditional Chinese medicine composition for soothing the nerves and helping sleep and the U-shaped suction so as to provide an easily accepted, simple, safe, effective and cheap alternative treatment mode for insomnia patients.
In order to achieve the above object, embodiments of the present application are implemented as follows:
in a first aspect, an embodiment of the present application provides a traditional Chinese medicine composition for soothing the nerves and aiding sleep, the traditional Chinese medicine composition is used for external application, active ingredients of the traditional Chinese medicine composition generate medicine aerosol in the air and enter a human body through a respiratory tract to take effect, and the traditional Chinese medicine composition at least comprises the following raw material medicines in parts by weight: 10 to 20 parts of keel, 10 to 20 parts of oyster, 7 to 13 parts of tuber fleeceflower stem, 7 to 13 parts of grassleaf sweelflag rhizome, 6 to 12 parts of rose, 6 to 12 parts of fortune eupatorium herb, 6 to 12 parts of finger citron, 4 to 8 parts of Chinese mugwort leaf, 2 to 4 parts of mint, 2 to 4 parts of rhizoma atractylodis and 2 to 4 parts of dried orange peel.
In the embodiment of the application, the dragon bones are neutral in nature, astringent in taste and sweet in flavor; the channels of heart, liver, kidney and large intestine; has effects of tranquilizing mind, suppressing hyperactive liver, subsiding yang, inducing astringency, and astringing. Can be used for treating palpitation, insomnia, amnesia, epilepsy, mania, dizziness, spontaneous perspiration, and night sweat. The oyster is cool in nature and salty in taste; entering liver and kidney meridians; has the effects of astringing yin, suppressing yang, suppressing sweating, controlling nocturnal emission, reducing phlegm and softening hard masses. Can be used for treating palpitation, insomnia, vertigo, tinnitus, spontaneous perspiration, and night sweat. Modern pharmacological studies show that the dragon bone has the effects of tranquilizing and allaying excitement, and is reinforced when being mutually reinforced, and the dragon bone is used together with the grassleaf sweelflag rhizome for astringing floating qi, improving the uneasiness of mind caused by yin-yang imbalance and reinforcing the effects of calming the heart and allaying excitement. The Concha Ostreae mainly contains calcium carbonate, calcium phosphate and calcium sulfate, and magnesium, aluminum, silicon and ferric oxide, and has effects of inhibiting excitability of nerve and muscle, reducing capillary permeability, enhancing humoral immunity, protecting liver and invigorating kidney. It is combined with Long Gu to reinforce the action of heavy-weight tranquilizing, so it is indicated for restlessness of mind, palpitation due to fright, insomnia and dream-disturbed sleep. The tuber fleeceflower stem is neutral in nature, sweet in taste and slightly bitter; heart and liver meridian entered; has the effects of nourishing heart, tranquilizing mind, dispelling pathogenic wind, and dredging collaterals. Can be used for treating insomnia, dreaminess, blood deficiency, body pain, and skin numbness. The use of caulis Polygoni Multiflori in combination with Os Draconis and Concha Ostreae can improve sleep improving effect. The rose is warm in nature and sweet and slightly bitter; enters liver and spleen meridians and has the functions of promoting qi circulation, relieving depression, regulating blood circulation and dissipating blood stasis. The rose and the grassleaf sweelflag rhizome are used together to strengthen the synergistic effect of soothing the liver, regulating qi, tranquilizing and allaying excitement. The eupatorium fortunei is pungent in flavor and enters spleen, stomach and lung meridians; the tea has fragrant smell and has the effects of eliminating dampness with fragrance, activating spleen and stimulating appetite; can be used for treating insomnia and dreaminess due to phlegm turbidity disturbing heart-mind. The herba eupatorii volatile oil has the effects of eliminating phlegm and inhibiting bacteria, the herba eupatorii is aromatic like orchid, summer-heat evil is removed to avoid foul smell, dampness is dissolved well to activate spleen and stomach, and the herba eupatorii volatile oil is combined with the rhizoma acori graminei to enhance the effects of dehumidifying, soothing nerves, soothing liver and regulating vital energy. The fingered citron is warm in nature and pungent, bitter and sour in taste; it enters liver, spleen, stomach and lung meridians; has the effects of soothing liver, regulating qi, harmonizing stomach, relieving pain, eliminating dampness and eliminating phlegm; the finger citron, the fortune eupatorium herb and the grassleaf sweelflag rhizome can be mutually matched to further strengthen the effect of soothing the liver and soothing the nerves. The folium artemisiae argyi is warm in nature and pungent and bitter in taste; entering liver, spleen and kidney meridians; has effects in warming channels, stopping bleeding, dispelling cold, and relieving pain; the folium artemisiae argyi and the eupatorium are used together to enter spleen channels and warm meridians to harmonize blood; the argy wormwood leaves, the rose and the finger citron are used together to enter liver and spleen channels, so that the effects of soothing liver and relieving depression, calming heart and soothing nerves are enhanced. The mint is cool in nature and pungent in taste; entering lung and liver meridians; has effects of dispelling pathogenic wind heat, clearing head and eyes, dispersing stagnated liver qi, and activating qi-flowing; not only can be used for aromatic flavoring, tranquilizing and clearing heart, but also can be used for soothing liver and relieving depression, clearing heart and improving eyesight; the combination of Bo He and Rose can strengthen the actions of soothing liver and qi stagnation. Rhizoma Atractylodis is pungent and bitter in flavor and warm in nature; spleen, stomach and liver meridians entered; has effects of eliminating dampness, invigorating spleen, dispelling pathogenic wind, dispelling cold, and improving eyesight. The dried orange peel is bitter and pungent in flavor and warm in nature; entering lung and spleen meridians; has the effects of regulating qi, strengthening spleen, eliminating dampness and phlegm. The traditional Chinese medicine composition in the scheme takes the dragon bones and the oysters as monarch drugs to play a role in tranquilizing mind; caulis Polygoni Multiflori and rhizoma Acori Tatarinowii as ministerial drugs for calming heart, tranquilizing mind, and benefiting mind; the rose, the fortune eupatorium herb, the finger citron and the Chinese mugwort leaf are used as adjuvant medicines for promoting qi circulation and relieving depression, and nourishing heart and soothing nerves; mint, rhizoma atractylodis and dried orange peel are used as guiding drugs, and the medicine has the functions of aromatic flavoring, promoting qi circulation, relieving depression, clearing away the heart-fire and soothing the nerves. The whole formula has the effects of soothing the nerves and helping sleep, and has the effects of coordinating yin and yang and paralleling qi and blood. The effective components of the raw material medicines of the traditional Chinese medicine composition can generate low-concentration medicine aerosol in the air, and the medicine aerosol takes effect in vivo through a respiratory tract, so that the effects of soothing the nerves, helping sleep, regulating yin and yang and paralleling qi and blood can be achieved.
With reference to the first aspect, in a first possible implementation manner of the first aspect, the weight ratio of the traditional Chinese medicine composition is: 15 parts of dragon bone, 15 parts of oyster, 10 parts of tuber fleeceflower stem, 10 parts of grassleaf sweelflag rhizome, 9 parts of rose, 9 parts of fortune eupatorium herb, 9 parts of finger citron, 6 parts of Chinese mugwort leaf, 3 parts of mint, 3 parts of rhizoma atractylodis and 3 parts of dried orange peel.
With reference to the first aspect, in a second possible implementation manner of the first aspect, the weight ratio of the traditional Chinese medicine composition is: 20 parts of dragon bone, 20 parts of oyster, 13 parts of tuber fleeceflower stem, 7 parts of grassleaf sweelflag rhizome, 10 parts of rose, 6 parts of fortune eupatorium herb, 8 parts of finger citron, 6 parts of Chinese mugwort leaf, 4 parts of mint, 4 parts of rhizoma atractylodis and 4 parts of dried orange peel.
With reference to the first aspect, in a third possible implementation manner of the first aspect, the weight ratio of the traditional Chinese medicine composition is: 10 parts of dragon bone, 10 parts of oyster, 7 parts of tuber fleeceflower stem, 7 parts of grassleaf sweelflag rhizome, 6 parts of rose, 6 parts of fortune eupatorium herb, 6 parts of finger citron, 4 parts of Chinese mugwort leaf, 2 parts of mint, 2 parts of rhizoma atractylodis and 2 parts of dried orange peel.
In a second aspect, an embodiment of the present application provides a U-shaped suction for soothing nerves and aiding sleep, including: the U-shaped clamp is provided with two opposite end parts and is used for extending into two nostrils through the two end parts to clamp the nasal cavity of a user, wherein each end part is provided with a ventilation accommodating cavity; each breathable containing cavity is internally provided with a composition medicine bag, wherein the composition medicine bag is prepared by pulverizing and packaging the raw material medicines of the traditional Chinese medicine composition for soothing the nerves and promoting sleep in any one of the first aspect or possible implementation manners of the first aspect.
In the embodiment of the application, the U-shaped clamp has two opposite end portions for inserting into two nostrils through the two end portions to clamp the nasal cavity of a user, and each end portion is provided with a breathable accommodating cavity for placing a composition medicine bag (prepared by pulverizing and packaging raw material medicines of the traditional Chinese medicine composition for soothing nerves and helping sleep). Therefore, when a user wants to sleep, the medicinal aerosol with low concentration is released in the nasal cavity of the user through the medicinal bag of the composition and enters the body through the respiratory tract to take effect, so that the effects of calming the nerves, helping sleep, harmonizing yin and yang and paralleling qi and blood can be achieved.
With reference to the second aspect, in a first possible implementation manner of the second aspect, the composition kit is prepared by: obtaining raw material medicines of the traditional Chinese medicine composition for soothing nerves and helping sleep of any one of the first aspect or possible implementation manners of the first aspect; cleaning and drying the raw materials in the traditional Chinese medicine composition, grinding the raw materials into powder, grinding the powder, and sieving the powder by using a 500-mesh sieve; and uniformly mixing the composition powder obtained after sieving, filling the mixture into a mini bag made of air-permeable materials, closing and packaging to obtain the composition medicine bag, wherein the size of the composition powder is more than 3 times of the size of pores of the air-permeable materials, and the mini bag can be placed into the accommodating cavity.
In the implementation mode, the raw material medicines in the traditional Chinese medicine composition are cleaned, dried in the sun, powdered and ground, and sieved by a 500-mesh sieve; the powder of the composition obtained after sieving is mixed uniformly and filled into mini bags made of breathable material and sealed closed. Therefore, the volatilization of the active ingredients in the raw material medicines is facilitated, so that the low-concentration medicine aerosol is continuously generated in the nasal cavity of a user and enters the body through the respiratory tract to take effect. In addition, the composition powder in the composition medicine bag can be effectively prevented from leaking out of the mini bag, and the quality of the composition medicine bag is ensured.
With reference to the first possible implementation manner of the second aspect, in a second possible implementation manner of the second aspect, in the process of preparing the composition medicine package, after the composition powder obtained by sieving is mixed uniformly, 5 parts of modified magnetite powder passing through a 200-mesh sieve are mixed, and after the mini-bag is filled and sealed, the sealed mini-bag is vibrated to remove the medicine powder with an undersized size in the mini-bag, so as to obtain the composition medicine package.
In this implementation, by adding the modified magnetite powder to the composition powder, the modified magnetite powder has hydrophobicity, and the interparticle friction force is reduced, which can prevent powder prepared from other raw materials from attaching to the modified magnetite powder, and can reduce the aggregation phenomenon between the magnetite powders as much as possible, thereby being more beneficial to the volatilization of the active ingredients of the composition powder. Therefore, the addition of modified magnetite powder to the composition powder can help to more effectively remove the undersized powder in the mini-bag by agitating the other powder with the magnetite powder during the vibration treatment; in addition, in the process of using the U-shaped sucker by a user, the modified magnetite powder in the composition medicine package can shake to stir other medicine powder, so that volatilization of effective components is facilitated, and the nerve soothing effect is ensured.
In a third aspect, an embodiment of the present application provides a U-shaped suction for soothing nerves and aiding sleep, including: the U-shaped clamp is provided with two opposite end parts and is used for extending into two nostrils through the two end parts to clamp the nasal cavity of a user, wherein each end part is provided with a ventilation accommodating cavity; a compressed tablet is placed in each air-permeable containing cavity, wherein the compressed tablet is obtained by pulverizing raw material medicines of the mind-tranquilizing sleep-aiding traditional Chinese medicine composition according to the first aspect or any one of the possible implementation manners of the first aspect and then compressing the pulverized raw material medicines into a tablet.
In this implementation, the U-shaped clamp has two opposite ends for probing into two nostrils through the two ends to clamp the nasal cavity of the user, and each end is provided with a breathable holding cavity for placing a tablet (formed by pulverizing the raw material of the traditional Chinese medicine composition for soothing the nerves and aiding sleep and then tabletting). Therefore, when a user wants to sleep, the low-concentration medicinal aerosol is released in the nasal cavity of the user by pressing the tablet and enters the body through the respiratory tract to take effect, so that the effects of calming the nerves, helping sleep, harmonizing yin and yang and paralleling qi and blood can be achieved.
In order to make the aforementioned objects, features and advantages of the present application more comprehensible, preferred embodiments accompanied with figures are described in detail below.
Drawings
To more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are required to be used in the embodiments of the present application will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and that those skilled in the art can also obtain other related drawings based on the drawings without inventive efforts.
Fig. 1 is a schematic diagram of pittsburgh sleep quality index before and after treatment according to an embodiment of the present application.
Description of the preferred embodiment
The technical solutions in the embodiments of the present application will be described below with reference to the drawings in the embodiments of the present application.
Example 1: the traditional Chinese medicine composition is used for external application, the active ingredients of the traditional Chinese medicine composition generate medicine aerosol in the air and enter a human body through a respiratory tract to take effect, and the traditional Chinese medicine composition at least comprises the following raw material medicines in parts by weight: 10 to 20 parts of keel, 10 to 20 parts of oyster, 7 to 13 parts of tuber fleeceflower stem, 7 to 13 parts of grassleaf sweelflag rhizome, 6 to 12 parts of rose, 6 to 12 parts of fortune eupatorium herb, 6 to 12 parts of finger citron, 4 to 8 parts of Chinese mugwort leaf, 2 to 4 parts of mint, 2 to 4 parts of rhizoma atractylodis and 2 to 4 parts of dried orange peel.
The mode of using the traditional Chinese medicine composition is as follows: pulverizing the raw materials of the Chinese medicinal composition, and packaging with gas-permeable material. For example, the health care product can be prepared into medicine bags (similar to sachet bags), U-shaped suckers and other articles, and is convenient for users to recuperate and use for a long time in daily life.
For example, 10 to 20g of keel, 10 to 20g of oyster, 7 to 13g of tuber fleeceflower stem, 7 to 13g of grassleaf sweetflag rhizome, 6 to 12g of rose, 6 to 12g of fortune eupatorium herb, 6 to 12g of fingered citron, 4 to 8g of folium artemisiae argyi, 2 to 4g of mint, 2 to 4g of rhizoma atractylodis and 2 to 4g of dried orange peel are used for preparing the sachet, so that the sachet is convenient for a user to carry, and the nerve calming effect is achieved.
Or using 100 to 200mg of keel, 100 to 200mg of oyster, 70 to 130mg of tuber fleeceflower stem, 70 to 130mg of grassleaf sweelflag rhizome, 60 to 120mg of rose, 60 to 120mg of eupatorium, 60 to 120mg of finger citron, 40 to 80mg of Chinese mugwort leaf, 20 to 40mg of mint, 20 to 40mg of rhizoma atractylodis and 20 to 40mg of dried orange peel to prepare a composition medicine bag used in combination with the U inhalation. Of course, in terms of dosage, a large amount of medicinal materials can be pulverized and then uniformly mixed to obtain a required amount (for example, the total amount of the medicinal materials is 1000g in the pulverizing process, and the required amount of the uniformly mixed medicinal powder is 1g in the using process), which is not limited herein.
For the convenience of understanding, the information of the above various raw material medicines is attached here:
keel: the part used as the medicine is skeleton fossilization. Mild in nature, astringent and sweet in taste; the channels of heart, liver, kidney and large intestine; has the effects of tranquilizing mind, suppressing hyperactive liver, subsiding yang, inducing astringency, and astringing. Can be used for treating palpitation, insomnia, amnesia, epilepsy, mania, dizziness, spontaneous perspiration, and night sweat. Modern pharmacological studies show that the dragon bone has the effects of tranquilizing and allaying excitement.
Oyster shell: is shell of Ostrea gigas Thunb, ostrea gigas Thunb or Ostrea gigas Thunb of Ostreidae. Cool in nature, salty in taste; entering liver and kidney meridians; has the effects of astringing yin, suppressing yang, suppressing sweating, controlling nocturnal emission, reducing phlegm and softening hard masses. Can be used for treating palpitation, insomnia, vertigo, tinnitus, spontaneous perspiration, and night sweat. Modern pharmacological research shows that oyster mainly contains calcium carbonate, calcium phosphate and calcium sulfate, magnesium, aluminum, silicon, iron oxide and the like. Has effects in inhibiting excitation of nerve and muscle, reducing capillary permeability, enhancing humoral immunity, protecting liver, and invigorating kidney.
Caulis Polygoni Multiflori: the part used as medicine is rattan of Polygonum multiflorum Thunb of Polygonaceae or rattan with leaves. Mild in nature, sweet and slightly bitter in taste; it enters heart and liver meridians; has the effects of nourishing heart, tranquilizing mind, dispelling pathogenic wind, and dredging collaterals. Can be used for treating insomnia, dreaminess, blood deficiency, body pain, and skin numbness. Modern pharmacological studies show that the tuber fleeceflower stem decoction has obvious sedative and hypnotic effects on mice after gastric lavage, and has synergistic effect with the sodium pentobarbital with subthreshold dose. The rat sleep polygraph shows an increase in total sleep time, mainly a slow wave sleep phase, and a reduction in the out-of-phase sleep phase.
Grassleaf sweelflag rhizome: the medicinal part is rhizome of Acorus tatarinowii Schott of Araceae. Warm in nature, pungent and bitter in flavor; heart and stomach meridians entered; has effects in inducing resuscitation, refreshing mind, eliminating dampness, regulating stomach function, tranquilizing mind, and benefiting mind. Can be used for treating vexation, amnesia, coma, and phlegm syncope. Modern pharmacological research shows that the grassleaf sweelflag rhizome has the functions of regulating the central nervous system, the vegetative nervous system, the endocrine system, the cardiovascular system and the digestive system, the main pharmacological action of the grassleaf sweelflag rhizome is the central tranquilizing and anti-convulsion action, and the water decoction, the volatile oil, or the asarone and the beta-asarone of the grassleaf sweelflag rhizome have the tranquilizing action. In addition, modern pharmacological studies show that the rhizoma acori graminei also has the effects of improving memory and resisting depression, the effective part of the depression is mainly in water extract and ethanol extract, and the depression resisting effect of the rhizoma acori graminei is probably related to the blockage of the reuptake of monoamine transmitters such as central 5-hydroxytryptamine and the like.
And (3) rose: the part used as the medicine is the flower originally placed in rose of Rosaceae. Warm in nature, sweet and slightly bitter; it enters liver and spleen meridians. The book materia medica justice cloud: rose, with the highest fragrance, is clear but not turbid, mild but not violent, soothes the liver and revives the stomach, and causes qi and blood circulation to be promoted. "herbal renewal" cloud: to soothe the depressed qi of the liver and gallbladder and invigorate the spleen to reduce pathogenic fire. Rose has the functions of promoting the circulation of qi, resolving stagnation, and dispersing blood stasis.
Herba Eupatorii: the part for administration is dried aerial part of Eupatorium fortunei of Compositae. Mild in nature and pungent in flavor; spleen, stomach and lung meridians entered; the tea has fragrant smell and has the effects of eliminating dampness with fragrance, activating spleen and stimulating appetite; can be used for treating insomnia and dreaminess due to phlegm turbidity disturbing heart-mind. Modern pharmacological studies show that the eupatorium volatile oil has the effects of eliminating phlegm and inhibiting bacteria, the eupatorium is fragrant like orchid, and additionally, the eupatorium volatile oil can eliminate summer-heat evil to avoid foul smell and can dissolve dampness to wake the spleen and the stomach.
Fingered citron: the part used as medicine is dried fruit of Rutaceae plant fructus Citri Sarcodactylis. Warm in nature, pungent, bitter and sour in flavor; entering liver, spleen, stomach and lung meridians; has the effects of soothing liver, regulating qi, harmonizing stomach, relieving pain, eliminating dampness and eliminating phlegm; can be used for treating qi stagnation of liver and stomach, distending pain in chest and hypochondrium, and epigastric fullness. The finger citron has fragrant smell and mild drug property, is a pungent, bitter and warm product, has no disadvantages of dryness and violence, can enter four channels of lung, liver, spleen and stomach, can be applied to all qi stagnation, and is used for treating chest distress due to lung qi stagnation and qi stagnation of spleen and stomach.
Folium artemisiae argyi: the medicinal part is dried leaf of Artemisia vulgaris L of Compositae. Warm in nature, pungent and bitter in taste; entering liver, spleen and kidney meridians; has effects in warming channels, stopping bleeding, dispelling cold, and relieving pain; it is said from the book of materia medica that it can warm the middle and relieve depression for regulating qi and blood.
Mint: the medicinal part is dried whole plant of herba Menthae of Labiatae. Cool in nature and pungent in flavor; entering lung and liver meridians; has effects of dispelling pathogenic wind heat, clearing head and eyes, dispersing stagnated liver qi, and activating qi-flowing; not only can be used for aromatic flavoring, tranquilizing and clearing heart, but also can be used for soothing liver and relieving depression, clearing heart and improving eyesight; is mainly used for treating insomnia caused by liver qi stagnation. New edition of materia medica cloud: mint is not good at dispelling wind evil, especially good at dispelling melancholy, cyperus rotundus is used for dispelling melancholy, and mint is not used for dispelling melancholy.
And (5) rhizoma atractylodis: the part used as medicine is dried rhizome of plant. Pungent and bitter with warm nature. It enters spleen, stomach and liver meridians. Has effects of eliminating dampness, invigorating spleen, dispelling pathogenic wind, dispelling cold, and improving eyesight.
Dried orange peel: the part used as medicine is dried mature pericarp of plant. Bitter and pungent in flavor and warm in nature. It enters lung and spleen meridians. Has the effects of regulating qi, strengthening spleen, eliminating dampness and phlegm.
The traditional Chinese medicine composition in the scheme takes the dragon bones and the oysters as monarch drugs, and plays a role in tranquilizing and allaying excitement; caulis Polygoni Multiflori and rhizoma Acori Graminei as ministerial drugs for calming heart and tranquilizing mind, and benefiting will; the rose, the eupatorium, the fingered citron and the folium artemisiae argyi are used as adjuvant medicines for promoting qi circulation and relieving depression, and nourishing heart and soothing nerves; the mint, the rhizoma atractylodis and the dried orange peel are used as guiding drugs, and the fragrant flavoring agent has the effects of promoting qi circulation, relieving depression, clearing away the heart-fire and soothing the nerves. Long Gu and Shi Chang Pu are combined together to astringe floating qi, improve unsteadiness of heart-mind caused by yin-yang imbalance and strengthen the effect of calming heart and tranquilizing mind. Mu Li and Long Gu are reinforced by mutual reinforcement to reinforce the action of tranquilizing mind, so they are indicated for restlessness of heart-mind, palpitation due to fright, insomnia and dreaminess. The use of caulis Polygoni Multiflori in combination with Os Draconis and Concha Ostreae can improve sleep improving effect. The rose and the grassleaf sweelflag rhizome are used together to strengthen the synergistic effect of soothing the liver, regulating qi, tranquilizing and allaying excitement. The combination of herba Eupatorii and rhizoma Acori Tatarinowii can enhance the effects of eliminating dampness, tranquilizing mind, dispersing stagnated liver qi, and regulating qi-flowing. The finger citron, the fortune eupatorium herb and the grassleaf sweelflag rhizome can be mutually matched to further strengthen the effect of soothing the liver and soothing the nerves. The folium artemisiae argyi and the eupatorium are used together to enter spleen channels and warm meridians to harmonize blood; the argy wormwood leaves, the rose and the finger citron are used together to enter liver and spleen channels, so that the effects of soothing liver and relieving depression, calming heart and soothing nerves are enhanced. The combination of Bo He and Rose can strengthen the actions of soothing liver and qi stagnation. The whole formula has the effects of soothing the nerves and helping sleep, and has the effects of coordinating yin and yang and paralleling qi and blood. The effective components of the raw materials of the traditional Chinese medicine composition can generate low-concentration medicinal aerosol in the air, and the medicinal aerosol enters the body through a respiratory tract to take effect, so that the effects of soothing the nerves, helping sleep, coordinating yin and yang and paralleling qi and blood can be achieved.
Example 2: based on the content in example 1, only the weight ratio of the traditional Chinese medicine composition is changed (the rest content is not described again): 15 parts of dragon bone, 15 parts of oyster, 10 parts of tuber fleeceflower stem, 10 parts of grassleaf sweelflag rhizome, 9 parts of rose, 9 parts of fortune eupatorium herb, 9 parts of finger citron, 6 parts of Chinese mugwort leaf, 3 parts of mint, 3 parts of rhizoma atractylodis and 3 parts of dried orange peel.
Example 3: 20 parts of dragon bone, 20 parts of oyster, 13 parts of tuber fleeceflower stem, 7 parts of grassleaf sweelflag rhizome, 10 parts of rose, 6 parts of fortune eupatorium herb, 8 parts of finger citron, 6 parts of Chinese mugwort leaf, 4 parts of mint, 4 parts of rhizoma atractylodis and 4 parts of dried orange peel.
Example 4: based on the content in the embodiment 1, only the weight ratio of the traditional Chinese medicine composition is changed (the rest content is not repeated): 10 parts of dragon bone, 10 parts of oyster, 7 parts of tuber fleeceflower stem, 7 parts of grassleaf sweelflag rhizome, 6 parts of rose, 6 parts of fortune eupatorium herb, 6 parts of finger citron, 4 parts of Chinese mugwort leaf, 2 parts of mint, 2 parts of rhizoma atractylodis and 2 parts of dried orange peel.
Of course, in the above embodiments, only the case that the traditional Chinese medicine composition for soothing the nerves and aiding sleep only contains the medicinal materials such as the keel, the oyster, the tuber fleeceflower stem, the grassleaf sweelflag rhizome, the rose, the fortune eupatorium herb, the finger citron, the argy wormwood leaf, the mint, the swordlike atractylodes rhizome, the tangerine peel and the like is introduced, in other embodiments, other auxiliary medicinal materials (such as clove) can be added, and the treatment effect of the traditional Chinese medicine composition for soothing the nerves and aiding sleep in the scheme is not weakened, which is within the protection scope of the present application.
Based on the same invention concept, the embodiment of the application provides the U-shaped suction for soothing the nerves and helping sleep.
In this embodiment, the U-suck for soothing nerves and helping sleep may include: a U-shaped clamp and a composition medicine bag prepared by grinding and packaging the raw material medicines of the traditional Chinese medicine composition.
Illustratively, the U-shaped clamp has two opposite ends for penetrating into two nostrils through the two ends to clamp the nasal cavity of the user, wherein each end is provided with an air-permeable accommodating cavity. And each of the breathable containment chambers may be used to house a pharmaceutical pack of the composition.
Therefore, when a patient wants to sleep, the medicinal aerosol with low concentration is released in the nasal cavity of the user through the medicinal bag of the composition and enters the body through the respiratory tract to take effect, so that the effects of calming the nerves, helping sleep, harmonizing yin and yang and paralleling qi and blood can be achieved.
In this example, the composition kit was prepared by: obtaining raw material medicines of the traditional Chinese medicine composition for soothing nerves and helping sleep; then cleaning the raw materials in the traditional Chinese medicine composition, drying in the sun, pulverizing, grinding, sieving with a 500-mesh sieve, uniformly mixing the sieved composition powder, filling into a mini bag made of a breathable material, and sealing to obtain the composition medicine bag. Wherein the size of the composition powder is more than 3 times of the pore size of the air-permeable material, and the mini-bag can be placed in the containing cavity.
Therefore, the volatilization of the active ingredients in the raw material medicines is facilitated, so that the low-concentration medicine aerosol is continuously generated in the nasal cavity of a user and enters the body through the respiratory tract to take effect. In addition, the composition powder in the composition medicine bag can be effectively prevented from leaking out of the mini bag, and the quality of the composition medicine bag is ensured.
In this example, in the process of manufacturing the composition pack, after the composition powder obtained by sieving is mixed uniformly, 5 parts of modified magnetite powder passing through a 200 mesh sieve may be mixed therein, and after filling in a mini-bag and closing and sealing, the sealed mini-bag may be subjected to a vibration treatment to remove the powder having an undersize inside the mini-bag, thereby obtaining the composition pack.
The modified magnetite powder has hydrophobicity and the friction force between particles is weakened. By adding the modified magnetite powder to the composition powder, the powder prepared from other raw materials can be prevented from being attached to the modified magnetite powder, and the aggregation phenomenon among the magnetite powders can be reduced as much as possible, thereby being more beneficial to the volatilization of the active ingredients of the composition powder. Therefore, the modified magnetite powder added to the composition powder can help to stir other powder by the magnetite powder during the vibration treatment, so as to remove the undersized powder in the mini-bag more effectively; in addition, in the process of using the U-shaped sucker by a user, the modified magnetite powder in the composition medicine package can shake to stir other medicine powder, so that volatilization of effective components is facilitated, and the nerve soothing effect is ensured. In addition, as the magnet also belongs to a severe tranquilizer, the magnet can be theoretically used as an adjuvant drug together with rose, fortune eupatorium herb, finger citron and folium artemisiae argyi to assist the drug effects of the dragon bone, the oyster (monarch drug), the tuber fleeceflower stem and the rhizoma acori graminei (ministerial drug) in the traditional Chinese medicine composition to be exerted, and an effect of mutually matching and promoting the drug effects to be exerted is formed.
In this embodiment, the U-shaped inhalation for soothing nerves and helping sleep may also include: a U-shaped clamp and a compressed tablet (which can be an ultrathin small tablet, for example, with a thickness of less than 1 mm) obtained by pulverizing the raw materials of the Chinese medicinal composition of the embodiment and then compressing into a tablet. That is, the effect is also good by using compressed tablets instead of composition packs. In addition, the composition powder of the traditional Chinese medicine composition in this embodiment can also be used for making other types of articles such as incense bags, and is not limited herein.
By utilizing the traditional Chinese medicine composition for soothing nerves and helping sleep provided by the invention, the inventor performs experiments:
the department of encephalopathy of traditional Chinese medicine hospital in Chongqing city is provided with an outpatient clinic for insomnia, and a large number of insomnia patients are received and diagnosed every year. In early-stage sleep outpatient service and ward use, the sleep quality and the sleep onset time of an insomnia patient begin to be obviously improved after the insomnia patient uses the prescription for 2 weeks, and the accompanying traditional Chinese medicine symptoms (difficult sleep onset, easy awakening and dreaminess, early awakening and the like) are correspondingly improved.
In the preliminary trial, a total of 223 cases were collected, and the results of the study are shown in table 1 and fig. 1:
TABLE 1 Pittsburgh sleep quality index Scale (PSQI) score before and after treatment
Figure SMS_1
In summary, the embodiment of the present application provides a traditional Chinese medicine composition for soothing nerves and aiding sleep and a U-shaped inhalant, wherein the traditional Chinese medicine composition takes fossilia ossis mastoid and oyster as monarch drugs to play a role in calming nerves; caulis Polygoni Multiflori and rhizoma Acori Tatarinowii as ministerial drugs for calming heart, tranquilizing mind, and benefiting mind; the rose, the eupatorium, the fingered citron and the folium artemisiae argyi are used as adjuvant medicines for promoting qi circulation and relieving depression, and nourishing heart and soothing nerves; the mint, the rhizoma atractylodis and the dried orange peel are used as guiding drugs, and the fragrant flavoring agent has the effects of promoting qi circulation, relieving depression, clearing away the heart-fire and soothing the nerves. Long Gu and Shi Chang Pu are combined together to astringe floating qi, improve unsteadiness of heart-mind caused by yin-yang imbalance and strengthen the effect of calming heart and tranquilizing mind. Mu Li and Long Gu are reinforced by mutual reinforcement to reinforce the action of tranquilizing mind, so they are indicated for restlessness of heart-mind, palpitation due to fright, insomnia and dreaminess. The use of caulis Polygoni Multiflori in combination with Os Draconis and Concha Ostreae can improve sleep promoting effect. The rose and the grassleaf sweelflag rhizome are used together to strengthen the synergistic effect of soothing the liver, regulating qi, tranquilizing and allaying excitement. The combination of herba Eupatorii and rhizoma Acori Tatarinowii can enhance the effects of eliminating dampness, tranquilizing mind, dispersing stagnated liver qi, and regulating qi-flowing. The finger citron, the fortune eupatorium herb and the grassleaf sweelflag rhizome can be mutually matched to further strengthen the effect of soothing the liver and soothing the nerves. The folium artemisiae argyi and the eupatorium are used together to enter spleen channels and warm meridians to harmonize blood; the argy wormwood leaves, the rose and the finger citron are used together to enter liver and spleen channels, so that the effects of soothing liver and relieving depression, calming heart and soothing nerves are enhanced. The combination of Bo He and Rose can strengthen the actions of soothing liver and qi stagnation. The whole formula has the effects of soothing the nerves and helping sleep, and has the effects of coordinating yin and yang and paralleling qi and blood. The effective components of the raw material medicines of the traditional Chinese medicine composition can generate low-concentration medicine aerosol in the air, and the medicine aerosol takes effect in vivo through a respiratory tract, so that the effects of soothing the nerves, helping sleep, regulating yin and yang and paralleling qi and blood can be achieved.
In this document, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions.
The above description is only an example of the present application and is not intended to limit the scope of the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims (5)

1. A U-shaped sucker for soothing nerves and helping sleep is characterized by comprising:
the U-shaped clamp is provided with two opposite end parts and is used for extending into two nostrils through the two end parts to clamp the nasal cavity of a user, wherein each end part is provided with a ventilation accommodating cavity;
each of the breathable containment chambers contains a composition pack, wherein the composition pack is prepared by:
the following traditional Chinese medicine composition in parts by weight is obtained as raw material medicine: 10 to 20 parts of keel, 10 to 20 parts of oyster, 7 to 13 parts of tuber fleeceflower stem, 7 to 13 parts of grassleaf sweelflag rhizome, 6 to 12 parts of rose, 6 to 12 parts of fortune eupatorium herb, 6 to 12 parts of finger citron, 4 to 8 parts of Chinese mugwort leaf, 2 to 4 parts of mint, 2 to 4 parts of rhizoma atractylodis and 2 to 4 parts of dried orange peel;
cleaning and drying the raw materials in the traditional Chinese medicine composition, grinding the raw materials into powder, grinding the powder, and sieving the powder by using a 500-mesh sieve;
and uniformly mixing the composition powder obtained after sieving, mixing 5 parts of modified magnetite powder passing through a 200-mesh screen, filling the mixture into the mini bag, closing and packaging, and then vibrating the packaged mini bag to remove the medicinal powder with undersize in the mini bag to obtain the composition medicine bag, wherein the size of the composition powder is more than 3 times of the size of the pores of the air-permeable material, and the mini bag can be placed into the accommodating cavity.
2. The U-shaped inhalant for soothing nerves and helping sleep according to claim 1, wherein the weight ratio of the traditional Chinese medicine composition is as follows: 15 parts of dragon bone, 15 parts of oyster, 10 parts of tuber fleeceflower stem, 10 parts of grassleaf sweelflag rhizome, 9 parts of rose, 9 parts of fortune eupatorium herb, 9 parts of finger citron, 6 parts of Chinese mugwort leaf, 3 parts of mint, 3 parts of Chinese atractylodes and 3 parts of tangerine peel.
3. The U-shaped inhalant for soothing nerves and aiding sleep according to claim 1, wherein the weight ratio of the traditional Chinese medicine composition is as follows: 20 parts of dragon bone, 20 parts of oyster, 13 parts of tuber fleeceflower stem, 7 parts of grassleaf sweelflag rhizome, 10 parts of rose, 6 parts of fortune eupatorium herb, 8 parts of finger citron, 6 parts of Chinese mugwort leaf, 4 parts of mint, 4 parts of rhizoma atractylodis and 4 parts of dried orange peel.
4. The U-shaped inhalant for soothing nerves and helping sleep according to claim 1, wherein the weight ratio of the traditional Chinese medicine composition is as follows: 10 parts of dragon bone, 10 parts of oyster, 7 parts of tuber fleeceflower stem, 7 parts of grassleaf sweelflag rhizome, 6 parts of rose, 6 parts of fortune eupatorium herb, 6 parts of finger citron, 4 parts of Chinese mugwort leaf, 2 parts of mint, 2 parts of rhizoma atractylodis and 2 parts of dried orange peel.
5. The U-shaped cigarette for soothing the nerves and aiding sleep according to claim 1, wherein the raw materials in the composition package can be further compressed into tablets after being pulverized.
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