CN113384623B - Braised polygonum multiflorum processing technology - Google Patents
Braised polygonum multiflorum processing technology Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
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Abstract
The invention provides a braise polygonum multiflorum processing technology, wherein polygonum multiflorum processed by the method contains key substances in an effective range, has better effect compared with the traditional steaming method, and provides a new direction for the medicinal use of polygonum multiflorum; the processing temperature curve fitted by a repeated archaizing processing simulation test is used for processing polygonum multiflorum, and compared with the traditional manual operation based on experience, the processing method is more energy-saving, stable, safe and environment-friendly; the electric heating jacket contains three groups of heating components, and can independently control heating according to the amount of liquid medicine in the tank, so that the heating accuracy is ensured, and meanwhile, the electric heating jacket is energy-saving and environment-friendly. In addition, the moistening process adopts the mixing of the medicinal juice and the gunny wine to treat the processed medicinal materials, so that various traditional Chinese medicinal components in the gunny wine are absorbed, and the medicinal effect is better.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine processing, and particularly relates to a braised polygonum multiflorum processing process.
Background
Polygonum multiflorum is a perennial winding vine of Polygonum genus of Polygonaceae family, and has thick root tuber, oblong shape and dark brown color. The root tuber of the Chinese medicinal composition is used as a medicament for soothing nerves, nourishing blood, activating collaterals, detoxifying and eliminating carbuncle; radix polygoni multiflori preparata can tonify essence and blood, blacken beard and hair, strengthen bones and muscles and nourish liver and kidney, and is a common precious and thin traditional Chinese medicine material.
Through research, the polygonum multiflorum contains the anthracene Engraulis japonicus Temminck et Schlegel derivative which mainly contains emodin and physcion, and the substance has the effect of causing diarrhea, so that the polygonum multiflorum Thunb is not suitable for patients with loose stool. The toxicity of the raw fleece-flower root is higher than that of the prepared fleece-flower root, for example, the raw fleece-flower root alcohol percolate for stomach perfusion LD50 of a white mouse is 50g/kg, the intraperitoneal injection LD50 is 2.7g/kg, the toxicity of the cold alcohol immersion liquid of the prepared fleece-flower root for abdominal injection of the white mouse is more than 54.5 times lower than that of the raw fleece-flower root alcohol immersion liquid, and the prepared fleece-flower root alcohol percolate for stomach perfusion of the white mouse is more than 20 times lower than that of the raw fleece-flower root alcohol percolate.
The Polygoni Multiflori radix contains gallic acid, stilbene glucoside, lecithin, fat, starch, and minerals besides anthraquinone compounds. Wherein lecithin is the main component of cerebrospinal, and is also the essential material of blood cell and other cell membranes, and can promote the new growth of blood cell, and has good invigorating effect. Free anthraquinones can promote cholesterol metabolism and inhibit intestinal resorption. Proper amount of gallic acid has antibacterial and antiviral effects, and stilbene glucoside derivative has effects of reducing serum cholesterol and protecting liver. Researches find that the medicinal value of the key substances of the polygonum multiflorum, such as gallic acid, stilbene glucoside, emodin and physcion, is higher in an effective range, and the medicinal effect is influenced by overhigh or overlow substances, for example, if the content of the gallic acid is overlow, the antibacterial effect is poor, and if the content of the gallic acid is overhigh, the absorption of the body to the medicine is influenced.
The processing of fresh fleece-flower root is a long-history and effective tool, the traditional processing method adopts bran fire processing, although the method has obvious effect of processing medicinal toxicity of fresh fleece-flower root, the method has many problems which are difficult to improve when used in modern production, such as 1, human factors: the time of temperature rise, heat preservation and temperature reduction is judged only by the experience of the old medical workers in each operation, and the reproducibility is poor; 2. environmental factors: the influence of environmental factors is big when traditional chaff fire is concocted and is heated, and temperature stability is poor, 3, environmental protection problem: the bran fire heating is easy to generate a large amount of waste gas and waste residue, which is not beneficial to environmental protection; 4. potential safety hazard: bran fire heating belongs to open fire production, and has great potential safety hazard for workshop production; for these problems, it is proposed in the industry to use modern intelligent temperature control equipment instead of bran fire heating, but the specific process curves of the heating, heat preservation and cooling stages for processing raw polygonum multiflorum are not standardized, and for polygonum multiflorum, the processing temperature is not equal to or greater than zero in the difference of the medicinal effect.
Therefore, aiming at all the problems, the invention provides a braised polygonum multiflorum processing process, which tests the content change of key substance groups of braised polygonum multiflorum processed in each group of experiments by using an archaizing processing simulation test and combining infrared spectrum and an electronic tongue as auxiliary testing tools, and finally successfully fits a processing temperature curve capable of replacing bran fire processing, so that a new processing standard is provided for the medicinal processing process of polygonum multiflorum.
Disclosure of Invention
The invention aims to: the braised polygonum multiflorum processing technology is provided, polygonum multiflorum is processed by a processing temperature curve fitted by an antique method and an electric heating jacket, and special product of Jiangxi Tuo and a braise pot with good thermal conductivity are supplemented, so that the effective content of key polygonum multiflorum substances is in a reasonable range, and the purpose of improving the medicinal effect of polygonum multiflorum is achieved.
The invention is realized by the following technical scheme: a braised polygonum multiflorum processing technology comprises the following steps:
fitting of a cooked polygonum multiflorum processing curve
The method comprises the steps of taking an archaizing method polygonum multiflorum processing technology and effective content of polygonum multiflorum key substance groups as test standards, taking bran addition and bran addition time intervals as variables to perform tests, testing content change of each group of experimentally processed slow polygonum multiflorum key substance groups through multi-group variable comparison test research and infrared spectrum and electronic tongue as auxiliary testing tools, selecting effective archaizing method groups, and fitting a slow polygonum multiflorum processing temperature standard curve according to time-temperature data recorded in a processing process.
The polygonum multiflorum critical substance group comprises gallic acid, stilbene glucoside, emodin, physcion, free emodin and free physcion;
the effective content range of the key substance group comprises:
the effective content range of the gallic acid is 0.12-0.15%;
the effective content range of the stilbene glucoside is 1.4 to 1.5 percent;
the effective content range of the emodin is 1.15% -1.25%;
the effective content range of the physcion is 0.7 to 0.9 percent;
the effective content of free emodin is above 0.2%;
the effective content of free physcion is above 0.1%.
The processing temperature standard curve of the braised polygonum multiflorum is specifically heating to boiling for 8-12h, then keeping constant-temperature boiling for 6-24h, and cooling for 4-12 h.
Processing with slow cooked polygonum multiflorum
(1) And medicinal material pretreatment: cleaning radix Polygoni Multiflori, removing impurities, and cutting into uniform pieces;
(2) and (3) moistening: mixing the butyl medicinal materials and drinking water according to the mass volume ratio of 10 kg: soaking for 12-24h at a proportion of 10-50L;
(3) and loading in a jar: taking out the medicinal materials, draining, adding into a braise pot, adding 8-10 parts of black bean in each pot, adding moistening liquid, heating to 40-50 deg.C, adding into an electric heating jacket, and transferring into a braise pot;
(4) braise: heating by adopting an electric heating jacket, processing according to the fitted braise polygonum multiflorum processing temperature standard curve in the first step, collecting residual medicine juice after braise processing is finished, taking out medicinal materials, drying, and screening out black beans for later use;
(5) moistening: mixing the medicinal materials in the step (4) with the mixed solution of the medicinal juice and the yellow wine, moistening, and taking out after completely sucking;
(6) and steaming: steaming the moistened Polygoni Multiflori radix for 4-8 hr, stewing for 10-15 hr until turning black, and taking out;
(7) and (3) drying: taking out the steamed polygonum multiflorum, and drying at the temperature of below 65 ℃ until the water content is less than or equal to 12 percent to obtain the polygonum multiflorum.
The electric heating jacket is internally provided with three groups of heating components which are respectively an upper heating component, a middle heating component, a lower heating component and three groups of heating components which can be independently controlled from top to bottom.
The amount of the yellow wine is 15-30% of the amount of the medicinal materials; the yellow wine is a gunny wine;
the volume mass ratio of the medicinal juice to the medicinal materials is 0.1-1.5L/kg;
the braise medicine pot is made of stainless steel or ceramics.
The invention has the advantages that:
(1) the polygonum multiflorum processed by the method contains key substances in an effective range, and has better effect compared with the traditional steaming method, so that a new direction is provided for the medicinal use of the polygonum multiflorum;
(2) the processing temperature curve fitted by the repeated archaizing processing simulation test is used for processing polygonum multiflorum, and compared with the traditional manual operation based on experience, the method is more energy-saving, stable, safe and environment-friendly;
(3) the electric heating sleeve is internally provided with three groups of heating components, and the heating can be controlled independently according to the amount of liquid medicine in the tank, so that the heating accuracy is ensured, and meanwhile, the electric heating sleeve is energy-saving and environment-friendly.
(4) The moistening process adopts the matching use of the medicinal juice and the gunny wine to process the processed medicinal materials, absorbs various traditional Chinese medicine components in the gunny wine, and has better medicinal effect.
In order to make the braised polygonum multiflorum processing process more clear and clear, the invention is further described with reference to the attached drawings and the detailed description.
Drawings
FIG. 1 is HPLC chromatogram of crude Polygonum multiflorum medicinal material
FIG. 2 is a slow-boiling polygonum multiflorum HPLC chromatogram in the embodiment of the invention
FIG. 3 is HPLC chromatogram of pharmacopeia radix Polygoni Multiflori Preparata
In the drawings:
peak 1: gallic acid
Peak 4: stilbene glucoside
Peak 12: emodin
Peak 13: physcion.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
To better illustrate the advantages of the technical scheme of the invention, the effect difference between the outside and the inside of the technical scope of the invention is compared transversely, and meanwhile, the polygonum multiflorum is processed by comparing other methods longitudinally, which is as follows:
example 1
A braised polygonum multiflorum processing technology comprises the following steps:
fitting of a cooked polygonum multiflorum processing curve
The method comprises the steps of taking an archaizing method polygonum multiflorum processing technology and effective content of key substances as test standards, taking the addition amount of bran and the bran addition time interval as variables for testing, testing content change of each group of experimentally processed slow polygonum multiflorum key substance groups through multi-group variable comparison test research and taking High Performance Liquid Chromatography (HPLC) and an electronic tongue as auxiliary testing tools, selecting effective archaizing method groups, and fitting a slow polygonum multiflorum processing temperature standard curve according to time-temperature data recorded in a processing process.
The polygonum multiflorum critical substance group comprises gallic acid, stilbene glucoside, emodin, physcion, free emodin and free physcion;
the effective content range of the key substance group comprises:
the effective content range of the gallic acid is 0.12-0.15%;
the effective content range of the stilbene glucoside is 1.4 to 1.5 percent;
the effective content range of the emodin is 1.15% -1.25%;
the effective content range of the physcion is 0.7 to 0.9 percent;
the effective content of free emodin is above 0.2%;
the effective content of free physcion is above 0.1%.
The processing temperature standard curve of the braised polygonum multiflorum is specifically heating to boiling for 10 hours, then keeping constant temperature boiling for 15 hours, and cooling for 8 hours.
Processing with slow cooked polygonum multiflorum
(1) And medicinal material pretreatment: cleaning radix Polygoni Multiflori, removing impurities, and cutting into uniform pieces;
(2) and (3) moistening: mixing the butyl medicinal materials and drinking water according to the mass volume ratio of 10 kg: soaking for 18h at the proportion of 30L;
(3) and loading in a jar: taking out the medicinal materials, draining, adding into a braise pot, adding 9 parts of black beans in each pot, adding emollient water, heating to 45 deg.C, adding into the pot, and transferring into an electric heating jacket;
(4) braise: heating by adopting an electric heating jacket, processing according to the fitted braise polygonum multiflorum processing temperature standard curve in the first step, collecting residual medicine juice after braise processing is finished, taking out medicinal materials, drying, and screening out black beans for later use;
(5) moistening: mixing the medicinal materials in the step (4) with the mixed solution of the medicinal juice and the yellow wine, moistening, and taking out after completely sucking;
(6) and steaming: steaming the moistened Polygoni Multiflori radix for 6 hr, stewing for 13 hr until turning black, and taking out;
(7) and (3) drying: taking out the steamed polygonum multiflorum, and drying at the temperature of below 65 ℃ until the water content is less than or equal to 12 percent to obtain the polygonum multiflorum.
The electric heating jacket is internally provided with three groups of heating components which are respectively an upper heating component, a middle heating component, a lower heating component and three groups of heating components which can be independently controlled from top to bottom.
The amount of the yellow wine is 22 percent of the amount of the medicinal materials; the yellow wine is a gunny wine;
the volume-mass ratio of the medicinal juice to the medicinal materials is 0.8L/kg;
the material of braise medicine jar is stainless steel.
Example 2
A braised polygonum multiflorum processing technology comprises the following steps:
(1) and medicinal material pretreatment: cleaning radix Polygoni Multiflori, removing impurities, and cutting into uniform pieces;
(2) and (3) moistening: mixing the butyl medicinal materials and drinking water according to the mass volume ratio of 10 kg: soaking for 12h at a proportion of 10L;
(3) and loading in a jar: taking out medicinal materials, draining, adding into a braise pot, adding 8 parts of black beans in each pot, adding emollient water, heating to 40 deg.C, adding into an electric heating jacket, and transferring into a braise pot;
(4) braise: heating with an electric heating jacket, processing according to a fitted braise Polygoni Multiflori radix processing temperature standard curve, collecting residual medicinal juice after braising, taking out medicinal materials, drying, and sieving to remove semen Sojae Atricolor;
(5) moistening: mixing the medicinal materials in the step (4) with the mixed solution of the medicinal juice and the yellow wine, moistening, and taking out after completely sucking;
(6) and steaming: steaming the moistened Polygoni Multiflori radix for 8 hr, stewing for 15 hr until turning black, and taking out;
(7) and (3) drying: taking out the steamed polygonum multiflorum, and drying at the temperature of below 65 ℃ until the water content is less than or equal to 12 percent to obtain the polygonum multiflorum.
The processing temperature standard curve of the braised polygonum multiflorum is specifically heating to boiling for 8 hours, then keeping constant temperature boiling for 6 hours, and cooling for 4 hours.
The amount of the yellow wine is 30 percent of the amount of the medicinal materials; the yellow wine is a gunny wine;
the volume-mass ratio of the medicinal juice to the medicinal materials is 1.5L/kg;
the braise medicine pot is made of ceramics.
The rest is the same as example 1.
Example 3
A braised polygonum multiflorum processing technology comprises the following steps:
(1) and medicinal material pretreatment: cleaning radix Polygoni Multiflori, removing impurities, and cutting into uniform pieces;
(2) and (3) moistening: mixing the butyl medicinal materials and drinking water according to the mass volume ratio of 10 kg: soaking for 24h at the proportion of 50L;
(3) and loading in a jar: taking out the medicinal materials, draining, adding into a braise pot, adding 10 parts of black beans into each pot, adding emollient water, heating to 50 deg.C, adding into a heating jacket, and transferring into a heating jacket;
(4) braise: heating with an electric heating jacket, processing according to a fitted braise Polygoni Multiflori radix processing temperature standard curve, collecting residual medicinal juice after braising, taking out medicinal materials, drying, and sieving to remove semen Sojae Atricolor;
(5) moistening: mixing the medicinal materials in the step (4) with the mixed solution of the medicinal juice and the yellow wine, moistening, and taking out after completely sucking;
(6) and steaming: steaming the moistened Polygoni Multiflori radix for 4 hr, stewing for 10 hr until turning black, and taking out;
(7) and (3) drying: taking out the steamed polygonum multiflorum, and drying at the temperature of below 65 ℃ until the water content is less than or equal to 12 percent to obtain the polygonum multiflorum.
The processing temperature standard curve of the braised polygonum multiflorum is specifically heating to boiling for 12 hours, then keeping constant-temperature boiling for 24 hours, and cooling for 12 hours.
The amount of the yellow wine is 15 percent of the amount of the medicinal materials; the yellow wine is a gunny wine;
the volume-mass ratio of the medicinal juice to the medicinal materials is 0.1L/kg;
the rest is the same as example 1.
Example 4
A braised polygonum multiflorum processing technology comprises the following steps:
(1) and medicinal material pretreatment: cleaning radix Polygoni Multiflori, removing impurities, and cutting into uniform pieces;
(2) and (3) moistening: mixing the butyl medicinal materials and drinking water according to the mass volume ratio of 10 kg: soaking for 11h at the proportion of 30L;
(3) and loading in a jar: taking out the medicinal materials, draining, adding into a braise pot, adding 7 parts of black beans per pot, adding emollient water, heating to 45 deg.C, adding into the pot, and transferring into an electric heating jacket;
(4) braise: heating with an electric heating jacket, processing according to a fitted braise Polygoni Multiflori radix processing temperature standard curve, collecting residual medicinal juice after braising, taking out medicinal materials, drying, and sieving to remove semen Sojae Atricolor;
(5) moistening: mixing the medicinal materials in the step (4) with the mixed solution of the medicinal juice and the yellow wine, moistening, and taking out after completely sucking;
(6) and steaming: steaming the moistened Polygoni Multiflori radix for 3 hr, stewing for 9 hr until turning black, and taking out;
(7) and (3) drying: taking out the steamed polygonum multiflorum, and drying at the temperature of below 65 ℃ until the water content is less than or equal to 12 percent to obtain the polygonum multiflorum.
The rest is the same as example 1.
Example 5
A braised polygonum multiflorum processing technology comprises the following steps:
(1) and medicinal material pretreatment: cleaning radix Polygoni Multiflori, removing impurities, and cutting into uniform pieces;
(2) and (3) moistening: mixing the butyl medicinal materials and drinking water according to the mass volume ratio of 10 kg: soaking for 25h at the proportion of 30L;
(3) and loading in a jar: taking out the medicinal materials, draining, adding into a braise pot, adding 11 parts of black beans in each pot, adding emollient water, heating to 45 deg.C, adding into an electric heating jacket, and transferring into a braise pot;
(4) braise: heating with an electric heating jacket, processing according to a fitted braise Polygoni Multiflori radix processing temperature standard curve, collecting residual medicinal juice after braising, taking out medicinal materials, drying, and sieving to remove semen Sojae Atricolor;
(5) moistening: mixing the medicinal materials in the step (4) with the mixed solution of the medicinal juice and the yellow wine, moistening, and taking out after completely sucking;
(6) and steaming: steaming the moistened Polygoni Multiflori radix for 9 hr, stewing for 16 hr, and taking out when turning black;
(7) and (3) drying: taking out the steamed polygonum multiflorum, and drying at the temperature of below 65 ℃ until the water content is less than or equal to 12 percent to obtain the polygonum multiflorum.
The rest is the same as example 1.
Comparative example 1
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 7 hours, then kept at constant temperature for 15 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 2
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 6 hours, then kept at constant temperature for 15 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 3
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 7.5 hours, then kept at constant temperature for boiling for 15 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 4
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 13 hours, then kept at constant temperature for 15 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 5
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 14 hours, then kept at constant temperature for 15 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 6
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is specifically heated to boiling for 12.5 hours, then kept at constant temperature for boiling for 15 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 7
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 10 hours, then kept at constant temperature for 5 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 8
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 10 hours, then kept at constant temperature for 4 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 9
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 10 hours, then kept at constant temperature for 5.5 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 10
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 10 hours, then kept at constant temperature for 25 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 11
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 10 hours, then kept at constant temperature for boiling for 26 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 12
A braised polygonum multiflorum processing technology is characterized in that a braised polygonum multiflorum processing temperature standard curve is heated to boiling for 10 hours, then kept at constant temperature for 25.5 hours, and cooled for 8 hours.
The rest is the same as example 1.
Comparative example 13
A processing technology of braised polygonum multiflorum is disclosed, wherein the dosage of yellow wine is 14% of the amount of medicinal materials; the yellow wine is a gunny wine;
the rest is the same as example 1.
Comparative example 14
A processing technology of braised polygonum multiflorum is disclosed, wherein the dosage of yellow wine is 31% of the amount of medicinal materials; the yellow wine is a gunny wine;
the rest is the same as example 1.
Comparative example 15
A processing method of slow braised Polygoni Multiflori radix comprises processing yellow wine with common yellow wine;
the rest is the same as example 1.
Test of
Processing Polygonum multiflorum according to the above examples and comparative example methods, respecting the principle of multiple experiments, combining high performance liquid chromatography and electronic tongue technology as an auxiliary analysis tool, referring to the effective content range of key substance group (the effective content range of gallic acid is 0.12% -0.15%, the effective content range of stilbene glucoside is 1.4% -1.6%, the effective content range of emodin is 1.15% -1.25%, the effective content range of physcion is 0.7% -0.9%, the effective content of free emodin is above 0.2%, the effective content of free physcion is above 0.1%), comparing the content change of the key substances gallic acid, stilbene glucoside, emodin and physcion of Polygonum multiflorum before and after processing, as shown in Table 1 below:
TABLE 1 comparison of major influencing ingredients before and after processing of braised Polygonum multiflorum
By comprehensively comparing the data in the table above, it can be found that:
(1) compared with various groups of data, the braised polygonum multiflorum processing technology provided by the method has the advantages that the effects of the embodiments 1, 2 and 3 are better, particularly the embodiment 1 has the best effect, and compared with parameters of other embodiments, the braised polygonum multiflorum processing technology provided by the method can be found out, so that the processing is very important for the medicinal value of polygonum multiflorum;
(2) in comparative example 1, the technical parameters of the braised polygonum multiflorum processing steps in examples 4 and 5 are out of range, and the quality of the braised polygonum multiflorum product is obviously inferior to that in example 1;
(3) in comparative example 1, the boiling time of the braised polygonum multiflorum is too short or too long according to the standard curve of the braised polygonum multiflorum prepared in comparative examples 1 to 6, which is not within the technical requirement range, while in comparative examples 7 to 12, the boiling time is too short or too long according to the constant temperature, the quality of the braised polygonum multiflorum prepared in comparative example 1 is not as good as that of the braised polygonum multiflorum prepared in example 1, and the content of corresponding key substance groups is not ideal;
(4) compared with the embodiment 1, the gunny wine in the comparative examples 13 and 14 has less or more addition amount, and the effect of the comparative example 15 in which yellow wine is used for replacing the gunny wine is not as good as that of the embodiment 1;
(5) and according to the comparison of the data, the processing temperature range of the braised polygonum multiflorum is that the heating time is 8-12h when the polygonum multiflorum is heated to boiling, then the constant-temperature boiling time is 6-24h, and the cooling time is 4-12h, preferably, the standard curve is that the heating time is 10h when the polygonum multiflorum is heated to boiling, then the constant-temperature boiling time is 15h, and the cooling time is 8 h.
Claims (4)
1. A braised polygonum multiflorum processing technology is characterized in that: the method comprises the steps of fitting a braised polygonum multiflorum processing curve and the braised polygonum multiflorum processing, wherein the fitting of the braised polygonum multiflorum processing curve specifically comprises the steps of taking the process of processing polygonum multiflorum by an antique method and the effective content of key substances as test standards, taking the addition amount of bran and the addition time interval of the bran as variables for testing, carrying out comparison test research by using multiple groups of variables, combining infrared spectrum and electronic tongue as auxiliary test tools, testing the content change of a braised polygonum multiflorum key substance group processed by each group of tests, selecting an effective antique method case group, and fitting the contents into a braised polygonum multiflorum processing temperature standard curve according to time-temperature data recorded in the processing process;
the polygonum multiflorum critical substance group comprises gallic acid, stilbene glucoside, emodin, physcion, free emodin and free physcion;
the effective content range of the polygonum multiflorum critical substance group comprises the following components:
the effective content range of the gallic acid is 0.12-0.15%;
the effective content range of the stilbene glucoside is 1.4 to 1.5 percent;
the effective content range of the emodin is 1.15% -1.25%;
the effective content range of the physcion is 0.7 to 0.9 percent;
the effective content of free emodin is above 0.2%;
the effective content of free physcion is more than 0.1 percent;
the processing temperature standard curve of the braised polygonum multiflorum is specifically heating to boiling for 8-12h, then keeping constant-temperature boiling for 6-24h, and cooling for 4-12 h;
the braised polygonum multiflorum is specifically processed as follows:
(1) and medicinal material pretreatment: cleaning radix Polygoni Multiflori, removing impurities, and cutting into uniform pieces;
(2) and (3) moistening: mixing the butyl medicinal materials and drinking water according to the mass volume ratio of 10 kg: soaking for 12-24h at a proportion of 10-50L;
(3) and loading in a jar: taking out the medicinal materials, draining, adding into a braise pot, adding 8-10 parts of black bean in each pot, adding moistening liquid, heating to 40-50 deg.C, adding into an electric heating jacket, and transferring into a braise pot;
(4) braise: heating with an electric heating jacket, processing according to a fitted braise Polygoni Multiflori radix processing temperature standard curve, collecting residual medicinal juice after braising, taking out medicinal materials, drying, and sieving to remove semen Sojae Atricolor;
(5) moistening: mixing the medicinal materials in the step (4) with the mixed solution of the medicinal juice and the yellow wine, moistening, and taking out after completely sucking;
(6) and steaming: steaming the moistened Polygoni Multiflori radix for 4-8 hr, stewing for 10-15 hr until turning black, and taking out;
(7) and (3) drying: taking out the steamed polygonum multiflorum, and drying at 65-85 ℃ until the water content is less than or equal to 12 percent to obtain the polygonum multiflorum.
2. The braised polygonum multiflorum processing process of claim 1, characterized in that: the electric heating jacket is internally provided with three groups of heating components which are respectively an upper heating component, a middle heating component, a lower heating component and three groups of heating components which can be independently controlled from top to bottom.
3. The braised polygonum multiflorum processing process of claim 1, characterized in that: the amount of the yellow wine is 15-30% of the amount of the medicinal materials; the yellow wine is a gunny wine; the volume-mass ratio of the medicinal juice to the medicinal materials is 0.1-1.5L/kg.
4. The braised polygonum multiflorum processing process of claim 1, characterized in that: the braise medicine pot is made of stainless steel or ceramics.
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| CN105456381A (en) * | 2015-12-11 | 2016-04-06 | 江西中医药高等专科学校 | Industrial processing technology and device of traditional Chinese medicine decoction piece braised polygonum multiflorum |
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| CN112603828A (en) * | 2020-12-22 | 2021-04-06 | 建昌帮药业有限公司 | Braise processing equipment and application thereof |
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| CN105456381A (en) * | 2015-12-11 | 2016-04-06 | 江西中医药高等专科学校 | Industrial processing technology and device of traditional Chinese medicine decoction piece braised polygonum multiflorum |
| CN205198469U (en) * | 2015-12-11 | 2016-05-04 | 江西中医药高等专科学校 | Small -size steam heating's traditional chinese medicine braise (boiling) pot |
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