CN113332372A - A Chinese medicinal composition for treating skin eczema, ulcer, scald and pruritus - Google Patents

A Chinese medicinal composition for treating skin eczema, ulcer, scald and pruritus Download PDF

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CN113332372A
CN113332372A CN202110763778.8A CN202110763778A CN113332372A CN 113332372 A CN113332372 A CN 113332372A CN 202110763778 A CN202110763778 A CN 202110763778A CN 113332372 A CN113332372 A CN 113332372A
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ulcer
itching
eczema
scald
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曹湘陵
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics

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Abstract

The invention discloses a traditional Chinese medicine composition for treating skin eczema, ulcer, scald and itching, which comprises the following components in parts by mass: 45-55 parts of carbonized sanguisorba root, 10-20 parts of white ginseng, 2-4 parts of borneol, 25-35 parts of rhizoma atractylodis, 25-35 parts of rhizoma paridis, 25-35 parts of Baijili and 15-25 parts of indigo naturalis. The prescription composition of the invention is mainly used for treating eczema, water itching, skin ulcer, various burns and scalds. Has the effects of cooling blood, removing blood stasis, diminishing inflammation, relieving pain, relieving itching, removing putrefaction, promoting granulation, and repairing wound surface, and the wound surface is smooth as before after healing; has no scar left, and has no symptoms such as atrophy and deformity. The invention has remarkable curative effect on treating infantile diaper eczema, adult eczema ulcer, itching, various burns and scalds, mild (I degree), moderate (II degree), severe (III degree) and severe wounds and the like. The invention has the advantages of simple raw material composition, wide source, proper price and the like, simple and convenient preparation, convenient and simple use, convenient carrying, quick curative effect, no toxic or side effect and the like.

Description

A Chinese medicinal composition for treating skin eczema, ulcer, scald and pruritus
Technical Field
The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for treating skin eczema, ulcer, scald and itching.
Background
The skin is the outermost layer of the human body and is the largest organ of the human body. It is both a sensory organ and an effector of the nervous system, and mechanical and chemical stimuli such as cold, heat, pain, emotional changes, etc. all reflexively cause the skin to contract and relax blood vessels. For example, changes in the contraction of the hair muscles, secretion of sweat glands, and permeability of skin capillaries. Our skin diseases reflect changes in the visceral and blood systems without reason. Participate in cell metabolism of all tissues and organs of the whole body, and have the effects of nourishing skin and treating skin diseases.
However, the skin is also the easiest to be injured, such as water and fire burns, bedsores, eczema, ulcers and the like, and currently, antibiotics are mostly adopted for treatment, dependence and drug resistance are easy to generate, resistance is weakened over time, and anaphylactic reaction is easy to occur.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating skin eczema, ulcer, scald and itching, and the composition has good treatment effect on diseases such as skin eczema, ulcer and the like.
The traditional Chinese medicine composition for treating skin eczema, ulcer, scald and itching comprises the following components in parts by mass: 45-55 parts of carbonized sanguisorba root, 10-20 parts of white ginseng, 2-4 parts of borneol, 25-35 parts of rhizoma atractylodis, 25-35 parts of rhizoma paridis, 25-35 parts of Baijili and 15-25 parts of indigo naturalis.
Preferably, the traditional Chinese medicine composition comprises the following components in parts by mass: 40 parts of carbonized sanguisorba root, 15 parts of white ginseng, 3 parts of borneol, 30 parts of rhizoma atractylodis, 30 parts of rhizoma paridis, 30 parts of white jili and 20 parts of indigo naturalis.
The preparation method of the traditional Chinese medicine composition comprises the following steps: firstly, drying and carbonizing garden burnet charcoal by medium fire in a microwave oven, then dehumidifying and drying ginseng, rhizoma atractylodis, rhizoma paridis and white fleshy root in the microwave oven by small fire, drying, crushing and sieving the dried ginseng, rhizoma atractylodis, rhizoma paridis and white fleshy root into powder in a crusher, then adding borneol and indigo naturalis, stirring and crushing the powder uniformly, and then putting the black powder finished product into a sealed container for storage; when in use, the medicinal powder is applied by washing the affected part with normal saline or tea saline; or mixing with sesame oil and tung oil, and applying to affected part.
Charring the garden burnet root: sour, astringent, cold in nature, clearing heat, bitter in taste, settling, directly reaching lower energizer, treating recklessly blood-heat syndrome in lower energizer, specially clearing blood-heat in lower energizer, and treating hematochezia, hematuria and metrorrhagia and metrostaxis; bitter and cool herbs with the actions of purging fire and removing toxicity, sour and astringent, astringing and promoting granulation, so it is a good herb for treating carbuncle, swelling, sore and toxicity, especially scald.
White ginseng: strengthen body resistance to eliminate pathogenic factors, stop bleeding, promote tissue regeneration.
Borneol: the resuscitative herbs also have the property of moving and fleeing, inducing stasis and closure, inducing resuscitation without obstruction, the natural and aromatic qi can repel all pathogenic factors and dispel all wind-heat with pungent and violent property; therefore, when the eyes are exposed to sudden red eyes, there are symptoms of swelling and pain, photophobia, or sore throat, abscess, fluid obstruction, headache due to cerebral wind, nasosinusitis at nose , swelling and pain due to external hemorrhoid, dripping of blood, or bone union, difficulty in fetal production, or invasion of wind-toxin into bone, numbness and spasm, or internal closure of pox-toxin, which is not smooth. The medicine is pungent, fragrant and strong in flavor, good in dispersing and dredging, extremely quick in effect, and not suitable for treating all the diseases of sudden and violent qi stagnation, phlegm accumulation and unconsciousness, and heat dissipation and pain relief by external application.
Rhizoma atractylodis: rhizoma Atractylodis is used as a medicine for activating spleen and resolving dampness, and has the actions of drying dampness, resolving turbidity and relieving pain, and mainly treating wind-cold-dampness arthralgia and muscular spasm and jaundice
Rhizoma paridis: bitter taste and slightly cold nature; has little toxicity; has the effects of clearing away heat and toxic materials, relieving swelling and pain, stopping endogenous wind and arresting convulsion, and can be used for treating furuncle, carbuncle, sore throat, snake and insect bite, traumatic injury, convulsion, and undefined lump
White disease: calming the liver, resolving stagnation, dispelling pathogenic wind and improving eyesight; can be used for treating vertigo, headache, hypochondriac pain, headache due to wind-heat, conjunctival congestion, swelling and pain, and skin pruritus, and for treating aversion to blood, and mass.
Indigo naturalis: is cold in nature and salty in taste, has the functions of clearing heat and purging fire, cooling blood and removing ecchymoses, and is externally applied to treat pyocutaneous disease and mumps.
The principle of the invention is as follows: the invention adopts 7 traditional Chinese medicine combined formulas of garden burnet root charcoal, white ginseng, borneol, rhizoma atractylodis, rhizoma paridis, tribulus terrestris and indigo naturalis as external application medicines, and the formulas are prepared according to the monarch, minister, assistant and guide principles, and the garden burnet root charcoal is mainly taken as the monarch to cool blood and reduce blood, and the rhizoma paridis, white Jili and the indigo naturalis are taken as the ministers to clear heat, cool blood, eliminate herpes, relieve itching and relieve pain; white ginseng and borneol are adjuvant drugs for strengthening body resistance to eliminate pathogenic factors and promoting granulation; rhizoma Atractylodis is used as a guiding drug to remove dampness, remove putrefaction and promote granulation; the medicines play the roles of monarch, minister, assistant and guide together to achieve the treatment purpose.
The invention has the beneficial effects that: 1) the prescription composition of the invention is mainly used for treating eczema, water itching, skin ulcer, various burns and scalds. Has the effects of cooling blood, removing blood stasis, diminishing inflammation, relieving pain, relieving itching, removing putrefaction, promoting granulation, and repairing wound surface, and the wound surface is smooth as before after healing; has no scar left, and has no symptoms such as atrophy and deformity. 2) The invention has remarkable curative effect on treating infantile diaper eczema, adult eczema ulcer, itching, various burns and scalds, mild (I degree), moderate (II degree), severe (III degree) and severe wounds and the like. 3) The invention has the advantages of simple raw material composition, wide source, proper price and the like, simple and convenient preparation, convenient and simple use, convenient carrying, quick curative effect, no toxic or side effect and the like. The prescription of the invention needs to be noticed when in use: avoiding smoking, drinking, pungent and spicy; for external use, it is contraindicated for oral administration.
Detailed Description
The present invention will be further illustrated by the following examples
Example 1:
the prescription of the embodiment is prepared by taking the following traditional Chinese medicines as raw materials:
50g of carbonized sanguisorba root, 15g of white ginseng, 3g of borneol, 30g of rhizoma atractylodis, 30g of rhizoma paridis, 30g of white jili and 20g of indigo naturalis.
The preparation method comprises the following steps: firstly, the garden burnet root charcoal is dehumidified, dried and carbonized by medium fire in a microwave oven, then the ginseng, the rhizoma atractylodis, the rhizoma paridis and the white Chinese wolfberry are dehumidified and dried by small fire in the microwave oven, the ginseng, the rhizoma atractylodis, the rhizoma paridis and the white Chinese wolfberry are put into a crusher to be crushed into powder, then the borneol and the indigo naturalis are added to be stirred and crushed evenly, and then the black powder finished product is put into a sealed container to be stored and is subpackaged for standby according to the situation.
The curative effect is as follows: when in use, the medicine powder is applied to the affected part by washing with normal saline or tea saline, and is most suitable for being carried in the field for standby.
The observation result of the trial curative effect of the product of the embodiment is shown in the following table 1; (clinical laboratory test)
TABLE 1 Observation of clinical efficacy of the product of example 1 controls statistics
Group of Number of examples Show effect Is effective Invalidation Total effective rate
The formulation of example 1 100 100 100 Is free of 100/100
Control product: skin-care cream 100 Is free of 50 50 50/100
The clinical curative effect observation has effective, effective and ineffective diagnosis standards that:
1. the effect is shown: eczema, hyperemia, water running, itching, scald, ulcer, blister and other symptoms disappear, the normal state is recovered, and the wound surface is smooth and has no scar.
2. The method has the following advantages: the symptoms are significantly reduced.
3. And (4) invalidation: the symptoms mentioned above did not change or worsen further.
Table 2 experimental observations of the effects of the product of example 1 on liver function
Figure RE-GDA0003199038390000031
Because of obvious curative effect and short time, the Chinese medicinal composition is directly applied to a human body, and no adverse abnormal reaction is found.
Example 2
Introduction of specific cases:
in case 1, certain Cao, certain Yang and certain Yin all were babies, diaper eczema, pudendum congestion, blister, yellow water flowing, successive ulcer, crying and crying (itching) appeared in about 2-4 months of birth, the baby skin health cream was ineffective in half a month after the use of talcum powder, and the formula of the invention in example 1 was changed to apply the cream in one day dry water and the cream in two days for blood withdrawal, and the baby skin health cream was recovered as usual in one week and not recurred.
In case 2, one patient with eczema of scrotum, congestion and itching is treated by using a skin healing cream and hospitalization antibacterial therapy, so that the patient is more ineffective, has running water ulcer, itching and pain and cannot walk. The formula in the embodiment 1 of the invention is changed to be externally applied for one day, itch is stopped, two days are carried out, blood is reduced, water is dried, skin regeneration is started for three days, and the skin is healed after one week.
In case 3, a certain patient on the left is paraplegic, because the burn area diameter at one inch of the ankle joint of the right lower limb of a trousers pipe and a trouser pipe which are burned by fire in winter is about 10 centimeters, the patient is not cured by applying the moist burn ointment, festers and antibiotics, the periphery is purulent and running water, the wound area depth is 1cm, the patient is not cured for a long time, the formula in the embodiment 1 of the invention is changed to be externally applied for one week, the concentrated water does not flow, the peripheral tender meat is born, the skin is regenerated and cured after one month, and the skin is smooth as before and has no scars.
Bedsore: the patient suffers from paraplegia, long-term sitting and lying, perianal and hip bedsore, and no pain caused by long-term treatment with antibiotics, skin healing cream and other medicines. The medicine of the invention is changed into the medicine, three days of dry water and ten days of skin recovery.

Claims (3)

1. A traditional Chinese medicine composition for treating skin eczema, ulcer, scald and itching is characterized by comprising the following components in parts by mass: 45-55 parts of carbonized sanguisorba root, 10-20 parts of white ginseng, 2-4 parts of borneol, 25-35 parts of rhizoma atractylodis, 25-35 parts of rhizoma paridis, 25-35 parts of Baijili and 15-25 parts of indigo naturalis.
2. The traditional Chinese medicine composition for treating skin eczema, ulcer, scald and itching as claimed in claim 1, is characterized by comprising the following components in parts by mass: 40 parts of carbonized sanguisorba root, 15 parts of white ginseng, 3 parts of borneol, 30 parts of rhizoma atractylodis, 30 parts of rhizoma paridis, 30 parts of white jili and 20 parts of indigo naturalis.
3. The method for preparing the traditional Chinese medicine composition according to claim 1 or 2, comprising the following steps: firstly, the garden burnet charcoal is dehumidified, dried and carbonized by medium fire in a microwave oven, then the ginseng, the rhizoma atractylodis, the rhizoma paridis and the white Chinese wolfberry are dehumidified and dried by small fire in the microwave oven, and are put into a crusher to be crushed and sieved into powder, then the borneol and the indigo naturalis are added to be stirred and crushed evenly, and then the black powder finished product is put into a sealed container to be stored; when in use, the medicinal powder is applied by washing the affected part with normal saline or tea saline; or mixing with sesame oil and tung oil, and applying to affected part.
CN202110763778.8A 2021-07-06 2021-07-06 A Chinese medicinal composition for treating skin eczema, ulcer, scald and pruritus Pending CN113332372A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103230452A (en) * 2013-04-23 2013-08-07 杨绍祥 Trauma paste and preparation method of trauma paste
CN110354181A (en) * 2019-05-30 2019-10-22 张志� A kind of Chinese medicine composition that treating scald or bedsore, drug and preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103230452A (en) * 2013-04-23 2013-08-07 杨绍祥 Trauma paste and preparation method of trauma paste
CN110354181A (en) * 2019-05-30 2019-10-22 张志� A kind of Chinese medicine composition that treating scald or bedsore, drug and preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
蒲昭和: "青黛外用治多种皮肤病", 《HTTP://WWW.CNTCM.COM.CN/XUESHU/2018-10/29/CONTENT_51801.HTM》 *
薛赛琴,等: "止痒霜治疗外阴瘙痒35例临床观察", 《中医杂志》 *

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