CN113329689A - 具有葡萄糖和酮双重检测特征的分析物传感器和感测方法 - Google Patents

具有葡萄糖和酮双重检测特征的分析物传感器和感测方法 Download PDF

Info

Publication number
CN113329689A
CN113329689A CN202080008102.1A CN202080008102A CN113329689A CN 113329689 A CN113329689 A CN 113329689A CN 202080008102 A CN202080008102 A CN 202080008102A CN 113329689 A CN113329689 A CN 113329689A
Authority
CN
China
Prior art keywords
active region
glucose
ketone
responsive active
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080008102.1A
Other languages
English (en)
Chinese (zh)
Inventor
B·J·费尔德曼
M·K·斯隆恩
A·库玛
N·基阿伊
M·R·洛夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Diabetes Care Co
Original Assignee
Abbott Diabetes Care Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Diabetes Care Co filed Critical Abbott Diabetes Care Co
Publication of CN113329689A publication Critical patent/CN113329689A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202080008102.1A 2019-01-28 2020-01-28 具有葡萄糖和酮双重检测特征的分析物传感器和感测方法 Pending CN113329689A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962797566P 2019-01-28 2019-01-28
US62/797,566 2019-01-28
US201962884869P 2019-08-09 2019-08-09
US62/884,869 2019-08-09
PCT/US2020/015365 WO2020159956A1 (en) 2019-01-28 2020-01-28 Analyte sensors and sensing methods featuring dual detection of glucose and ketones

Publications (1)

Publication Number Publication Date
CN113329689A true CN113329689A (zh) 2021-08-31

Family

ID=69845516

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080008102.1A Pending CN113329689A (zh) 2019-01-28 2020-01-28 具有葡萄糖和酮双重检测特征的分析物传感器和感测方法

Country Status (13)

Country Link
US (9) US20200237275A1 (enExample)
EP (5) EP4574038A3 (enExample)
JP (4) JP7196315B2 (enExample)
CN (1) CN113329689A (enExample)
AU (3) AU2020216325B2 (enExample)
CA (1) CA3123053A1 (enExample)
DK (1) DK3917396T3 (enExample)
ES (1) ES2995203T3 (enExample)
FI (1) FI3917396T3 (enExample)
LT (1) LT3917396T (enExample)
MX (2) MX2021008964A (enExample)
MY (1) MY196781A (enExample)
WO (1) WO2020159956A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116718657A (zh) * 2023-06-12 2023-09-08 深圳木芯科技有限公司 葡萄糖生物传感膜的制备方法及葡萄糖生物传感器
CN116735885A (zh) * 2023-05-25 2023-09-12 深圳硅基传感科技有限公司 多分析物监测传感器
WO2025060050A1 (en) * 2023-09-22 2025-03-27 Medtrum Technologies Inc. A structurally enhanced analyte sensor with multi substrates

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3423591T3 (da) 2016-03-04 2024-01-29 Abbott Diabetes Care Inc NAD(P)-afhængige sensitive enzymer, elektroder og sensorer og fremgangsmåder til fremstilling og anvendelse deraf
CN118105070A (zh) 2019-01-28 2024-05-31 美国雅培糖尿病护理公司 用于双重检测葡萄糖和乙醇的分析物传感器和感测方法
EP3917394B1 (en) 2019-01-28 2024-08-14 Abbott Diabetes Care Inc. Analyte sensors employing multiple enzymes
AU2020419193B2 (en) 2020-01-03 2024-07-04 Abbott Diabetes Care Inc. Sensor array systems and methods for detecting multiple analytes
WO2021242501A1 (en) 2020-05-29 2021-12-02 Abbott Diabetes Care Inc. Analyte sensors and sensing methods for detecting inhibitors of diaphorase
EP4164491A4 (en) 2020-06-16 2024-07-03 Abbott Diabetes Care Inc. ANALYTICAL SENSORS WITH A REDUCED WORKING ELECTRODE TO REDUCE INTERFERING SIGNALS
EP4165400A4 (en) 2020-06-16 2024-07-10 Abbott Diabetes Care Inc. ANALYTICAL SENSORS WITH WORKING ELECTRODE APERITY PLANING TO REDUCE INTERFERING SIGNALS
US12465251B2 (en) 2020-07-08 2025-11-11 Abbott Diabetes Care Inc. Analyte sensors featuring enhancements for decreasing interferent signal
CA3200345A1 (en) * 2020-12-10 2022-06-16 Abbott Diabetes Care Inc. Analyte sensors for sensing ketones and methods of using the same
CN116829068A (zh) * 2020-12-10 2023-09-29 美国雅培糖尿病护理公司 用于传感酮的分析物传感器和使用其的方法
AU2021400588B2 (en) 2020-12-15 2025-04-10 Abbott Diabetes Care Inc. Nad(p) depot for nad(p)-dependent enzyme-based sensors
MX2023007637A (es) 2020-12-23 2023-09-21 Abbott Diabetes Care Inc Sensores de analito con señal interferente reducida y métodos.
US20220192553A1 (en) * 2020-12-23 2022-06-23 Abbott Diabetes Care Inc. Analyte sensors for sensing glutamate and methods of using the same
CN117098852A (zh) * 2020-12-30 2023-11-21 美国雅培糖尿病护理公司 用于检测天冬酰胺和天冬氨酸的分析物传感器及其使用方法
CA3202248A1 (en) * 2020-12-31 2022-07-07 Zenghe Liu Analyte sensors and methods of use thereof
US20220233116A1 (en) * 2021-01-26 2022-07-28 Abbott Diabetes Care Inc. Systems, devices, and methods related to ketone sensors
US12226239B2 (en) 2021-09-15 2025-02-18 Lingo Sensing Technology Unlimited Company Systems, devices, and methods for applications for communication with ketone sensors
US12442786B2 (en) 2021-10-14 2025-10-14 Medtronic Minimed, Inc. Sensors for 3-hydroxybutyrate detection
US20230172497A1 (en) * 2021-12-02 2023-06-08 Medtronic Minimed, Inc. Ketone limiting membrane and dual layer membrane approach for ketone sensing
EP4558048A1 (en) 2022-07-19 2025-05-28 Abbott Diabetes Care, Inc. Analyte sensors with reduced interferent signal and methods
EP4382611A1 (en) * 2022-08-31 2024-06-12 Medtronic MiniMed, Inc. Sensors for 3-hydroxybutyrate detection
AU2023410876A1 (en) * 2022-12-23 2025-05-22 Abbott Diabetes Care Inc. Systems and methods for analyte monitoring
WO2024145651A1 (en) * 2022-12-30 2024-07-04 Dexcom, Inc. Sensing systems and methods for hybrid glucose and ketone monitoring
AU2024205934A1 (en) 2022-12-30 2025-04-17 Abbott Diabetes Care Inc. Drug delivery compositions and methods of controlling drug delivery rates of subcutaneous sensors
EP4655412A2 (en) 2023-01-25 2025-12-03 Abbott Diabetes Care, Inc. Temperature-insensitive membranes for analyte sensors
AU2024248719A1 (en) 2023-03-31 2025-10-02 Abbott Diabetes Care, Inc. Ascorbate blocking membrane
WO2024243577A1 (en) 2023-05-24 2024-11-28 Abbott Diabetes Care Inc. Methods for incorporating therapeutic agents into analyte sensors
WO2024249832A1 (en) * 2023-06-01 2024-12-05 The University Of North Carolina At Chapel Hill R-3-hydroxybutyrate binding proteins (bhbbps) and their use for ketone monitoring
WO2025064882A2 (en) 2023-09-22 2025-03-27 Abbott Diabetes Care Inc. Decision support for glucose-ketone sensor
WO2025137203A1 (en) 2023-12-19 2025-06-26 Abbott Diabetes Care, Inc. Glucose oxidase sensors with improved stability

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1322254A (zh) * 1998-10-08 2001-11-14 特拉森斯公司 含有可扩散的或不可滤出的氧化还原介质的小容积体外分析传感器
CN101360450A (zh) * 2006-02-27 2009-02-04 爱德华兹生命科学公司 用于静脉电流计生物传感器的流量限制膜
WO2010027771A1 (en) * 2008-08-27 2010-03-11 Edwards Lifesciences Corporation Analyte sensor
CN102047101A (zh) * 2008-03-28 2011-05-04 德克斯康公司 用于连续的分析物传感器的聚合物膜
CN102165070A (zh) * 2008-09-15 2011-08-24 雅培糖尿病护理公司 用于分析物传感器的基于阳离子聚合物的有线酶制剂
US20130211219A1 (en) * 2010-08-24 2013-08-15 Micro CHIPS ,Inc. Implantable Biosensor Device and Methods of Use Thereof
US20190004005A1 (en) * 2017-06-30 2019-01-03 Abbott Diabetes Care Method and apparatus for analyte detection using an electrochemical biosensor

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6736957B1 (en) * 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
GB2337122B (en) * 1998-05-08 2002-11-13 Medisense Inc Test strip
US8444834B2 (en) 1999-11-15 2013-05-21 Abbott Diabetes Care Inc. Redox polymers for use in analyte monitoring
TR200401326T4 (tr) 1999-11-15 2004-07-21 Therasense, Inc. İmidazol halkasına sahip iki dişli ligant içeren geçiş metali kompleksleri
US8268143B2 (en) 1999-11-15 2012-09-18 Abbott Diabetes Care Inc. Oxygen-effect free analyte sensor
US7501053B2 (en) 2002-10-23 2009-03-10 Abbott Laboratories Biosensor having improved hematocrit and oxygen biases
US20050067277A1 (en) * 2003-09-30 2005-03-31 Pierce Robin D. Low volume electrochemical biosensor
JP4802842B2 (ja) 2006-04-24 2011-10-26 株式会社デンソー 健康管理支援装置及び健康管理システム
US8808515B2 (en) 2007-01-31 2014-08-19 Abbott Diabetes Care Inc. Heterocyclic nitrogen containing polymers coated analyte monitoring device and methods of use
WO2008157820A1 (en) 2007-06-21 2008-12-24 Abbott Diabetes Care, Inc. Health management devices and methods
ES2779630T3 (es) * 2007-09-24 2020-08-18 Ascensia Diabetes Care Holdings Ag Sistema de biosensor con múltiples electrodos
WO2009060432A1 (en) 2007-11-07 2009-05-14 Medingo Ltd. Device and method for preventing diabetic complications
JPWO2009139101A1 (ja) 2008-05-13 2011-09-15 パナソニック株式会社 電子機器システム、および半導体集積回路のコントローラ
US8620398B2 (en) * 2008-06-02 2013-12-31 Abbott Diabetes Care Inc. Reference electrodes having an extended lifetime for use in long term amperometric sensors
EP2400886A4 (en) 2009-02-26 2014-07-02 Abbott Diabetes Care Inc IMPROVED ANALYTICAL SENSORS AND METHOD FOR THEIR MANUFACTURE AND USE
WO2011008357A1 (en) 2009-06-30 2011-01-20 Abbott Diabetes Care Inc. Extruded electrode structures and methods of using same
US20110048972A1 (en) * 2009-08-31 2011-03-03 Lifescan Scotland Limited Multi-analyte test strip with shared counter/reference electrode and inline electrode configuration
WO2011025549A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Medical devices and methods
ES2670676T3 (es) 2009-09-04 2018-05-31 Lifescan Scotland Limited Método para determinar una corriente de prueba corregida por hematocritos en mediciones de glucosa
US8545693B2 (en) * 2009-09-29 2013-10-01 Lifescan Scotland Limited Analyte measurment method and system
US8323467B2 (en) * 2009-10-27 2012-12-04 Lifescan Scotland Limited Dual chamber, multi-analyte test strip with opposing electrodes
JP5551419B2 (ja) * 2009-11-27 2014-07-16 株式会社イノアックコーポレーション ダクト
US20140054171A1 (en) * 2012-02-21 2014-02-27 Abbott Diabetes Care Inc. Analyte Sensor Utilizing Oxygen as Oxidant
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
DE202014011533U1 (de) 2013-12-27 2021-12-16 Abbott Diabetes Care, Inc. Systeme und Vorrichtungen zur Authentifizierung in einer Analytüberwachungsumgebung
US9775549B2 (en) * 2014-08-15 2017-10-03 Abbott Diabetes Care Inc. Temperature insensitive in vivo analyte devices, methods and systems
AU2016258193A1 (en) * 2015-05-07 2017-08-17 Dexcom, Inc. System and method for educating users, including responding to patterns
EP3523640B1 (en) * 2016-10-05 2023-01-18 Abbott Laboratories Devices for sample analysis
EP3531120A4 (en) * 2016-10-24 2020-06-10 PHC Holdings Corporation ELECTRON MEDIATOR OXIDIZING AGENT

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1322254A (zh) * 1998-10-08 2001-11-14 特拉森斯公司 含有可扩散的或不可滤出的氧化还原介质的小容积体外分析传感器
CN101360450A (zh) * 2006-02-27 2009-02-04 爱德华兹生命科学公司 用于静脉电流计生物传感器的流量限制膜
CN102047101A (zh) * 2008-03-28 2011-05-04 德克斯康公司 用于连续的分析物传感器的聚合物膜
WO2010027771A1 (en) * 2008-08-27 2010-03-11 Edwards Lifesciences Corporation Analyte sensor
CN102165070A (zh) * 2008-09-15 2011-08-24 雅培糖尿病护理公司 用于分析物传感器的基于阳离子聚合物的有线酶制剂
US20130211219A1 (en) * 2010-08-24 2013-08-15 Micro CHIPS ,Inc. Implantable Biosensor Device and Methods of Use Thereof
US20190004005A1 (en) * 2017-06-30 2019-01-03 Abbott Diabetes Care Method and apparatus for analyte detection using an electrochemical biosensor

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116735885A (zh) * 2023-05-25 2023-09-12 深圳硅基传感科技有限公司 多分析物监测传感器
WO2024239485A1 (zh) * 2023-05-25 2024-11-28 深圳硅基传感科技有限公司 多分析物监测传感器
WO2024240266A1 (zh) * 2023-05-25 2024-11-28 深圳硅基传感科技有限公司 多分析物监测传感器
CN116735885B (zh) * 2023-05-25 2025-02-11 深圳硅基传感科技有限公司 多分析物监测传感器
CN116718657A (zh) * 2023-06-12 2023-09-08 深圳木芯科技有限公司 葡萄糖生物传感膜的制备方法及葡萄糖生物传感器
WO2025060050A1 (en) * 2023-09-22 2025-03-27 Medtrum Technologies Inc. A structurally enhanced analyte sensor with multi substrates

Also Published As

Publication number Publication date
MX2025009473A (es) 2025-09-02
US20230128038A1 (en) 2023-04-27
ES2995203T3 (en) 2025-02-07
US20230119512A1 (en) 2023-04-20
US20230118818A1 (en) 2023-04-20
US20230123384A1 (en) 2023-04-20
EP4509046A3 (en) 2025-03-26
CA3123053A1 (en) 2020-08-06
MX2021008964A (es) 2021-08-24
US20230121367A1 (en) 2023-04-20
AU2025203882A1 (en) 2025-06-19
MY196781A (en) 2023-05-03
EP4574038A2 (en) 2025-06-25
EP4606303A1 (en) 2025-08-27
JP7634121B2 (ja) 2025-02-20
JP2023027266A (ja) 2023-03-01
US20230122702A1 (en) 2023-04-20
JP2025069427A (ja) 2025-04-30
WO2020159956A1 (en) 2020-08-06
AU2022283734B2 (en) 2025-02-27
JP2024052892A (ja) 2024-04-12
AU2022283734A1 (en) 2023-02-02
JP7196315B2 (ja) 2022-12-26
EP3917396A1 (en) 2021-12-08
EP4574038A3 (en) 2025-08-27
LT3917396T (lt) 2024-12-27
US20230121769A1 (en) 2023-04-20
EP4509046A2 (en) 2025-02-19
AU2020216325B2 (en) 2022-09-08
US20230121101A1 (en) 2023-04-20
JP7448621B2 (ja) 2024-03-12
JP2022516279A (ja) 2022-02-25
AU2020216325A1 (en) 2021-06-17
EP3917396B1 (en) 2024-09-04
FI3917396T3 (fi) 2024-11-29
EP4643777A1 (en) 2025-11-05
US20200237275A1 (en) 2020-07-30
DK3917396T3 (da) 2024-12-02

Similar Documents

Publication Publication Date Title
JP7634121B2 (ja) グルコースとケトンの二重検出を特徴とする分析対象物センサー及び検出方法
JP7524288B2 (ja) グルコース及びエタノールのデュアル検出のための分析物センサ
JP7669463B2 (ja) 複数の酵素を用いた分析物センサ

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination