CN113317845A - Pulse balloon with grounding treatment on inner wall and application thereof - Google Patents

Pulse balloon with grounding treatment on inner wall and application thereof Download PDF

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Publication number
CN113317845A
CN113317845A CN202110307434.6A CN202110307434A CN113317845A CN 113317845 A CN113317845 A CN 113317845A CN 202110307434 A CN202110307434 A CN 202110307434A CN 113317845 A CN113317845 A CN 113317845A
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CN
China
Prior art keywords
balloon
wall
pulse
voltage
sacculus
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Granted
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CN202110307434.6A
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Chinese (zh)
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CN113317845B (en
Inventor
汪立
张晨朝
梁鑫峰
蔡涛
王君毅
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Shanghai Baixin'an Biotechnology Co ltd
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Shanghai Baixin'an Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B17/22012Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/109Balloon catheters with special features or adapted for special applications having balloons for removing solid matters, e.g. by grasping or scraping plaque, thrombus or other matters that obstruct the flow

Abstract

The invention relates to the field of medical equipment, in particular to a pulse balloon with an inner wall subjected to grounding treatment, which comprises a balloon with a cavity inside, an inner tube penetrating through the middle part of the balloon, a voltage divider arranged in the cavity of the balloon and n high-voltage pulse power supplies arranged in the cavity of the balloon, wherein two ends of the balloon extend outwards to form a mouthpiece, and two ends of the inner tube extend outwards and penetrate through the mouthpiece. Set up bleeder mechanism in the sacculus, at sacculus during operation, be full of electrolyte with the sacculus body through the mouth-piece, make high-voltage pulse power emit pulse high-voltage electricity and produce the pulse, along with electrolyte spreads the vibrations that drive the sacculus for the electric energy is mostly converted into mechanical energy, punctures hematal calcification region, and remaining high voltage is transmitted ground by bleeder mechanism, has avoided the conduction of high voltage on the sacculus surface, restricts the unnecessary high-voltage electricity of pulse source department.

Description

Pulse balloon with grounding treatment on inner wall and application thereof
Technical Field
The invention relates to the field of medical instruments, in particular to a pulse balloon with an inner wall subjected to grounding treatment and application thereof.
Background
Aortic calcification, also known as aortic sclerosis, is the build-up of calcium deposits on the aortic valve in the heart. Aortic calcification can have a very serious impact on the health of the human body.
The main artery calcification is mainly treated clinically at present by puncturing or shattering the calcification area. For example, CN104582597A, CN 109223100A, CN 111184553A, CN 104519809 a and the like all disclose a shock wave balloon structure that uses the vibration of the electrolyte driven by the pulse to make the inner wall of the balloon perform physical vibration, and the generated physical vibration and the calcified region of the blood vessel are used as countermeasures to achieve the purpose of breaking down or shattering the calcified region. The shock wave balloon disclosed in the above patent generates pulses that propagate through the liquid by cathodic and anodic discharges within the balloon. During the discharge, the cathode and the anode generate high voltage, and the wall thickness of the balloon is particularly thin. The thin wall can be punctured to some high-voltage electricity in the conduction through electrolyte, and some high-voltage electricity can appear in the outside of sacculus, thereby the high-voltage electricity leads to the rhythm of the heart to receive the interference on patient's blood vessel, causes the secondary damage to the patient, influences patient's health.
Disclosure of Invention
In order to solve the problems, the invention provides a pulse balloon with a grounded inner wall, which comprises a balloon with a cavity inside, an inner tube penetrating through the middle of the balloon, a voltage divider arranged in the balloon cavity, and n high-voltage pulse power supplies arranged in the balloon cavity, wherein two ends of the balloon extend outwards to form a mouthpiece, and two ends of the inner tube extend outwards and penetrate through the mouthpiece.
Preferably, the pressure dividing device comprises an upper grounding wire and a lower grounding wire, one end of the upper grounding wire is connected to the upper end of the inner wall of the balloon, and the other end of the upper grounding wire extends out of the balloon along the inner tube and is grounded; one end of the lower grounding wire is connected to the lower end of the inner wall of the balloon, and the other end of the lower grounding wire extends out of the balloon along the inner tube and is grounded.
Preferably, the upper grounding wire and the lower grounding wire are both bonded to the inner wall of the balloon.
Preferably, the upper grounding wire and the lower grounding wire are integrally formed with the balloon.
Preferably, the high-voltage pulse power supply is sleeved on the periphery of the outer wall of the inner pipe.
Preferably, the high-voltage pulse power supply comprises an anode layer, an insulating layer and a cathode layer from inside to outside in sequence.
Preferably, the anode layer comprises two anode blocks.
Preferably, the high voltage pulse power supply comprises a first high voltage pulse power supply and a second high voltage pulse power supply which are electrically connected.
Preferably, both ends of the balloon are in a slope shape at the mouthpiece.
The pulse balloon with the grounding-connection-processed inner wall is applied to aortic calcification treatment.
Has the advantages that:
(1) set up bleeder mechanism in the sacculus, at sacculus during operation, be full of electrolyte with the sacculus body through the mouth-piece, make high-voltage pulse power emit pulse high-voltage electricity and produce the pulse, along with electrolyte spreads the vibrations that drive the sacculus for the electric energy is mostly converted into mechanical energy, punctures hematal calcification region, and remaining high voltage is transmitted ground by bleeder mechanism, has avoided the conduction of high voltage on the sacculus surface, restricts the unnecessary high-voltage electricity of pulse source department.
(2) The sacculus with partial pressure device in this technical scheme can prevent unnecessary electric conduction to pace-making point, signal conduction region etc. makes patient's rhythm of the heart can keep a relatively stable state.
(3) When a patient with serious calcification is faced, the high-voltage pulse power supply and the discharge frequency can be increased, and the effectiveness of the operation is improved while the damage to the human body is avoided.
(4) All set up the earth connection in the upper surface and the lower surface of sacculus among this technical scheme, guarantee the stability of partial pressure.
(5) Use bonding or integrated into one piece's mode to be connected earth connection and sacculus among this technical scheme, improve the combination degree of earth connection and sacculus wall, guarantee the stability in the use.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic view of the overall structure of a pulse balloon whose inner wall is subjected to grounding treatment in example 1.
Fig. 2 is a schematic view of the overall structure of the high-voltage pulse power supply in embodiment 1.
The device comprises a balloon 1, an inner tube 2, an upper grounding wire 3, a lower grounding wire 4, a first high-voltage pulse power supply 5, a second high-voltage pulse power supply 6, an anode block 7, a cathode layer 8, an interface tube 9 and an insulating layer 10.
Detailed Description
The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.
The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.
In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings or the orientations or positional relationships that the products of the present invention are conventionally placed in use, and are only used for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the devices or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
Furthermore, the terms "horizontal", "vertical", "overhang" and the like do not imply that the components are required to be absolutely horizontal or overhang, but may be slightly inclined. For example, "horizontal" merely means that the direction is more horizontal than "vertical" and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.
In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In order to solve the problems, the invention provides a pulse balloon with a grounded inner wall, which comprises a balloon with a cavity inside, an inner tube penetrating through the middle of the balloon, a voltage divider arranged in the balloon cavity, and n high-voltage pulse power supplies arranged in the balloon cavity, wherein two ends of the balloon extend outwards to form a mouthpiece, and two ends of the inner tube extend outwards and penetrate through the mouthpiece.
Set up bleeder mechanism in the sacculus, at sacculus during operation, be full of electrolyte with the sacculus body through the mouth-piece, make high-voltage pulse power emit pulse high-voltage electricity and produce the pulse, along with electrolyte spreads the vibrations that drive the sacculus for the electric energy is mostly converted into mechanical energy, punctures hematal calcification region, and remaining high voltage is transmitted ground by bleeder mechanism, has avoided the conduction of high voltage on the sacculus surface, restricts the unnecessary high-voltage electricity of pulse source department.
As a preferred technical scheme, the pressure dividing device comprises an upper grounding wire and a lower grounding wire, one end of the upper grounding wire is connected to the upper end of the inner wall of the balloon, and the other end of the upper grounding wire extends out of the balloon along the inner tube and is grounded; one end of the lower grounding wire is connected to the lower end of the inner wall of the balloon, and the other end of the lower grounding wire extends out of the balloon along the inner tube and is grounded.
All set up the earth connection in the upper surface and the lower surface of sacculus among this technical scheme, guarantee the stability of partial pressure.
As a preferred technical scheme, the upper grounding wire and the lower grounding wire are both bonded on the inner wall of the balloon.
As a preferred technical scheme, the upper grounding wire and the lower grounding wire are integrally formed with the balloon.
Use bonding or integrated into one piece's mode to be connected earth connection and sacculus among this technical scheme, improve the combination degree of earth connection and sacculus wall, guarantee the stability in the use.
As a preferred technical scheme, the high-voltage pulse power supply is sleeved on the circumference of the outer wall of the inner pipe.
As a preferred technical solution, the high voltage pulse power supply sequentially includes an anode layer, an insulating layer, and a cathode layer from inside to outside.
As a preferred solution, the anode layer comprises two anode blocks.
As a preferable technical solution, the high voltage pulse power supply includes a first high voltage pulse power supply and a second high voltage pulse power supply which are electrically connected.
When a patient with serious calcification is faced, the high-voltage pulse power supply and the discharge frequency can be increased, and the effectiveness of the operation is improved while the damage to the human body is avoided.
As a preferred technical scheme, both ends of the balloon are in a slope shape at the interface tube.
In the technical scheme, the two ends of the balloon are both in the slope shape at the interface tube, so that the resistance of the balloon in the use process can be reduced, and the smoothness of the balloon in the body of a patient is improved.
The pulse balloon with the grounding-connection-processed inner wall is applied to aortic calcification treatment.
Examples
The present invention will be specifically described below by way of examples. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention.
Example 1
As shown in fig. 1, this embodiment provides a pulse balloon with ground connection processing on an inner wall, where the pulse balloon with ground connection processing on the inner wall includes a balloon 1 with a cavity inside, an inner tube 2 penetrating through the middle of the balloon 1, a voltage divider arranged in the cavity of the balloon 1, and 2 circumferential high-voltage pulse power supplies installed in the cavity of the balloon 1 and located on the outer wall of the inner tube 2, where the high-voltage pulse power supplies are a first high-voltage pulse power supply 5 and a second high-voltage pulse power supply 6, two ends of the balloon extend outward to form a mouthpiece 9, two ends of the inner tube 2 extend outward and pass through the mouthpiece 9, and two ends of the balloon 1 are both in a slope shape at the mouthpiece 9. The pulse saccule with the inner wall being grounded charges electrolyte into the cavity of the saccule through the mouthpiece 9. The pressure dividing device comprises an upper grounding wire 3 and a lower grounding wire 4, one end of the upper grounding wire 3 is bonded to the upper end of the inner wall of the balloon 1, and the other end of the upper grounding wire extends out of the balloon 1 along the inner tube 2 and is grounded; one end of the lower grounding wire 3 is bonded to the lower end of the inner wall of the balloon 1, the other end of the lower grounding wire extends out of the balloon along the inner tube 2 and is grounded, and the upper grounding wire 3 and the lower grounding wire 4 are grounded simultaneously. As shown in fig. 2, the first high voltage pulse power supply 5 sequentially includes, from inside to outside, an anode layer, an insulating layer 10 connected to the anode layer, and a cathode layer 8 connected to the insulating layer 10, where the anode layer includes two anode blocks 7. Before the saccule works, electrolyte is charged into the saccule 1 until the inside of the saccule 1 is filled with the electrolyte. When the cathode layer and the anode layer 8 emit pulse high-voltage electricity, pulses can be generated, the pulses are transmitted through electrolyte to drive the saccule 1 to vibrate to puncture the calcified area of a blood vessel, when discharging, a part of high-voltage electricity can puncture the saccule, and the part of high-voltage electricity can be transmitted to the ground along a wire.
Example 2
The embodiment provides a pulse sacculus that ground connection was handled is done to inner wall, the pulse sacculus that ground connection was handled is done to inner wall includes that inside is equipped with the sacculus of cavity, runs through the inner tube in sacculus middle part, sets up the partial pressure device in the sacculus cavity, installs in the sacculus cavity and is located the individual high-voltage pulse power of circumference of inner tube outer wall, high-voltage pulse power is first high-voltage pulse power and second high-voltage pulse power respectively, and the both ends of show sacculus all outwards extend and form the mouth-piece, the both ends of inner tube all outwards extend and pass the mouth-piece, the both ends of sacculus are slope form in the mouth-piece department. The pulse saccule with the inner wall being grounded charges electrolyte into the cavity of the saccule through the interface tube. The pressure dividing device comprises an upper grounding wire and a lower grounding wire, one end of the upper grounding wire is connected to the upper end of the inner wall of the balloon, and the other end of the upper grounding wire extends out of the balloon along the inner pipe and is grounded; the one end of lower earth connection is connected in the lower extreme of sacculus inner wall, and the other end extends the sacculus and ground connection along the inner tube, go up earth connection and lower earth connection ground connection simultaneously, last earth connection and lower earth connection and sacculus integrated into one piece in this embodiment. The first high-voltage pulse power supply sequentially comprises an anode layer, an insulating layer connected with the anode layer and a cathode layer connected with the insulating layer from inside to outside. Before the saccule works, electrolyte is charged into the saccule until the inside of the saccule is full of the electrolyte. When the cathode layer and the anode layer emit pulse high-voltage electricity, pulses can be generated, the pulses are transmitted through electrolyte to drive the saccule to vibrate and puncture the calcified area of the blood vessel, when discharging, a part of high-voltage electricity can puncture the saccule, and the part of high-voltage electricity can be transmitted to the ground along the lead.
The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.

Claims (10)

1. The pulse balloon with the inner wall subjected to grounding treatment is characterized by comprising a balloon, an inner tube, a voltage divider and n high-voltage pulse power supplies, wherein a cavity is formed in the balloon, the inner tube penetrates through the middle of the balloon, the voltage divider is arranged in the cavity of the balloon, the n high-voltage pulse power supplies are installed in the cavity of the balloon, two ends of the balloon extend outwards to form a connector tube, and two ends of the inner tube extend outwards and penetrate through the connector tube.
2. The pulse balloon with the inner wall subjected to grounding treatment according to claim 1, wherein the voltage divider comprises an upper grounding wire and a lower grounding wire, one end of the upper grounding wire is connected to the upper end of the inner wall of the balloon, and the other end of the upper grounding wire extends out of the balloon along the inner tube and is grounded; one end of the lower grounding wire is connected to the lower end of the inner wall of the balloon, and the other end of the lower grounding wire extends out of the balloon along the inner tube and is grounded.
3. The pulse balloon with the inner wall subjected to grounding treatment according to claim 2, wherein the upper grounding wire and the lower grounding wire are both bonded to the inner wall of the balloon.
4. The pulse balloon with the ground-connection-processed inner wall as claimed in claim 2, wherein the upper ground wire and the lower ground wire are integrally formed with the balloon.
5. The pulse balloon with the ground-connection processed inner wall according to claim 1, wherein the high-voltage pulse power supply is sleeved on the circumference of the outer wall of the inner tube.
6. The pulse balloon with the ground-connection processed inner wall according to claim 1, wherein the high-voltage pulse power supply comprises an anode layer, an insulating layer and a cathode layer from inside to outside in sequence.
7. The pulse balloon with the ground-connection-processed inner wall according to claim 1, wherein the anode layer comprises two anode blocks.
8. The pulse balloon with the ground-connection-processed inner wall according to claim 1, wherein the high-voltage pulse power supply comprises a first high-voltage pulse power supply and a second high-voltage pulse power supply which are electrically connected.
9. The pulse balloon with the ground-connection-processed inner wall according to claim 1, wherein both ends of the balloon are in a slope shape at the mouthpiece.
10. The pulse balloon with the ground-connection-treated inner wall according to any one of claims 1 to 9 is applied to aortic calcification treatment.
CN202110307434.6A 2021-03-23 2021-03-23 Pulse saccule with grounding treatment on inner wall Active CN113317845B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114305652A (en) * 2021-12-09 2022-04-12 深圳先进技术研究院 Micropore electrode for blood vessel calcification breaking treatment
CN114587500A (en) * 2022-04-06 2022-06-07 上海百心安生物技术股份有限公司 Transduction pulse sacculus expansion pipe

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US20150238208A1 (en) * 2008-06-13 2015-08-27 Shockwave Medical, Inc. Shockwave balloon catheter system
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US20150366608A1 (en) * 2014-06-20 2015-12-24 Boston Scientific Scimed, Inc. Medical device for sympathetic nerve ablation with printed components
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CN109303586A (en) * 2017-07-26 2019-02-05 波士顿科学国际有限公司 Blast wave generating apparatus
US20200129195A1 (en) * 2018-10-24 2020-04-30 Boston Scientific Scimed, Inc. Photoacoustic pressure wave generation for intravascular calcification disruption
CN112220526A (en) * 2020-12-10 2021-01-15 上海百心安生物技术有限公司 Pulse balloon and using method

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Publication number Priority date Publication date Assignee Title
US5047028A (en) * 1989-05-12 1991-09-10 Quinghua Qian Method for inducing thrombosis in blood vessels
US5609606A (en) * 1993-02-05 1997-03-11 Joe W. & Dorothy Dorsett Brown Foundation Ultrasonic angioplasty balloon catheter
US20150238208A1 (en) * 2008-06-13 2015-08-27 Shockwave Medical, Inc. Shockwave balloon catheter system
CN104582597A (en) * 2012-06-27 2015-04-29 冲击波医疗公司 Shock wave balloon catheter with multiple shock wave sources
US20150320432A1 (en) * 2014-05-08 2015-11-12 Shockwave Medical, Inc. Shock wave guide wire
US20150366608A1 (en) * 2014-06-20 2015-12-24 Boston Scientific Scimed, Inc. Medical device for sympathetic nerve ablation with printed components
CN109303586A (en) * 2017-07-26 2019-02-05 波士顿科学国际有限公司 Blast wave generating apparatus
CN108452426A (en) * 2018-03-16 2018-08-28 上海心至医疗科技有限公司 A kind of foley's tube based on electrohydraulic effect
US20200129195A1 (en) * 2018-10-24 2020-04-30 Boston Scientific Scimed, Inc. Photoacoustic pressure wave generation for intravascular calcification disruption
CN112220526A (en) * 2020-12-10 2021-01-15 上海百心安生物技术有限公司 Pulse balloon and using method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114305652A (en) * 2021-12-09 2022-04-12 深圳先进技术研究院 Micropore electrode for blood vessel calcification breaking treatment
CN114587500A (en) * 2022-04-06 2022-06-07 上海百心安生物技术股份有限公司 Transduction pulse sacculus expansion pipe

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