CN113304230A - Traditional Chinese medicine composition for treating diabetic foot and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating diabetic foot and preparation method thereof Download PDF

Info

Publication number
CN113304230A
CN113304230A CN202110537897.1A CN202110537897A CN113304230A CN 113304230 A CN113304230 A CN 113304230A CN 202110537897 A CN202110537897 A CN 202110537897A CN 113304230 A CN113304230 A CN 113304230A
Authority
CN
China
Prior art keywords
parts
traditional chinese
chinese medicine
medicine composition
decocting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110537897.1A
Other languages
Chinese (zh)
Inventor
戴皓
顾经宇
周宁天
付麒
蒋琳
王玉成
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Province Hospital First Affiliated Hospital Of Nanjing Medical University
Original Assignee
Jiangsu Province Hospital First Affiliated Hospital Of Nanjing Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Province Hospital First Affiliated Hospital Of Nanjing Medical University filed Critical Jiangsu Province Hospital First Affiliated Hospital Of Nanjing Medical University
Priority to CN202110537897.1A priority Critical patent/CN113304230A/en
Publication of CN113304230A publication Critical patent/CN113304230A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835Aquilaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Insects & Arthropods (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Dermatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)

Abstract

The invention provides a traditional Chinese medicine composition for treating diabetic foot and a preparation method thereof, wherein the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 8-12 parts of asarum, 8-11 parts of pseudo-ginseng, 9-10 parts of dragon's blood, 9-10 parts of stiff silkworm, 9-11 parts of rhizoma arisaematis and 10-11 parts of radix stemonae. The traditional Chinese medicine composition provided by the invention is reasonable in compatibility, can fully exert the drug effects of the components, ensures the medication safety, and has a remarkable synergistic effect. Has obvious treatment effect on diabetic feet such as blood vessels blocked below the ankle, neuropathic foot ulcers, nerve-ischemic foot ulcers, lower limb venous disease degenerative ulcers and the like which cannot be solved by western medicine. And can be used according to the specific conditions of diabetic foot patients.

Description

Traditional Chinese medicine composition for treating diabetic foot and preparation method thereof
Technical Field
The invention relates to a medicinal preparation for treating diabetic foot, in particular to a Chinese medicinal preparation for treating diabetic foot, which contains Chinese medicinal materials for strengthening body resistance, dialectical clearing heat and promoting diuresis, drawing out toxin and removing putrefaction, freeing channels and dissolving stasis, promoting muscle growth and promoting nerve repair, and a preparation method thereof.
Background
Diabetic foot disease is a serious complication of diabetes, and has long treatment period, high cost, high amputation rate, high recurrence rate and high death rate. Foot ulcers can be classified as neuropathic, ischemic and neuro-ischemic ulcers. At present, the key means of treating serious diabetic foot ulcer in western medicine is to solve the problem of lower limb arterial stenosis through operations such as saccule, stent and rotary cutting. Not only lacks means for directly promoting the regeneration and repair of peripheral blood vessels, peripheral nerves and wound tissue cells, but also has no effective treatment means for blood vessels occlusion below the ankle, or neuropathic foot ulcer, nerve-ischemic foot ulcer and lower limb venous disease degenerative ulcer. In addition, for patients with severe diabetic foot osteomyelitis, the use of antibiotics needs more than 6 weeks, the risk of double infection, multiple drug resistance or tuberculosis infection is high, and the prognosis of the patients is poor. The traditional Chinese medicine has the effects of clearing heat, promoting diuresis, drawing out toxin, removing putrefaction, dredging channels, removing blood stasis, promoting granulation, promoting nerve repair and the like in treating diabetic feet, and has certain advantages and characteristics.
In view of the above, in terms of clinical treatment of diabetic foot, especially for the blood vessel occlusion under ankle, neuropathic foot ulcer, nerve-ischemic foot ulcer and lower limb venous disease degenerative ulcer which are limited by the traditional western medicine treatment means, development of a traditional Chinese medicine preparation capable of effectively treating diabetic foot is required.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a traditional Chinese medicine composition for treating diabetic foot and a preparation method thereof. .
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine composition for treating diabetic foot is prepared from the following raw material medicines in parts by weight: 8-12 parts of asarum, 8-11 parts of pseudo-ginseng, 9-10 parts of dragon's blood, 9-10 parts of stiff silkworm, 9-11 parts of rhizoma arisaematis and 10-11 parts of radix stemonae.
A traditional Chinese medicine composition for treating diabetic foot comprises the following traditional Chinese medicine components in a preferable proportion by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts.
For mild diabetic foot patients without obvious wounds, asarum which has the effects of warming lung and dredging orifices and inducing diuresis to alleviate edema is combined; sanguis Draxonis with effects of promoting blood circulation, dispelling blood stasis, stopping bleeding, and relieving pain; stiff silkworm and rhizoma arisaematis with the functions of dispelling wind and extinguishing wind and relieving spasm and pain, panax notoginseng with the functions of relieving swelling and pain and stemona with the functions of killing parasites and relieving itching are prepared into a paste formula which is applied to a wound, the medicine can penetrate deep into blood vessels and channels and collaterals, and deeply penetrate into bones and marrow along with the dredging of the channels and collaterals and the flowing of blood and qi, so that the blood oxygen of abnormal and unconnected tissues can be obtained again, and the clinical symptoms of a patient can be effectively improved.
Furthermore, aiming at the diabetes patients with large pus volume, unhealing sores and unclean slough, the traditional Chinese medicine composition for treating diabetic foot is added with the following raw material medicines in parts by weight: 0-2 parts of red mercuric oxide, 8-10 parts of trichosanthes root and 1-3 parts of calomel.
A traditional Chinese medicine composition for treating diabetic foot for patients with large pus volume, unhealing sores and unclean slough, wherein the traditional Chinese medicine composition comprises the following components in a preferable ratio by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts, red mercuric oxide 1 part, root of Chinese trichosannthes 9 parts, and calomel 2 parts.
For diabetic foot patients with large pus volume, unhealing sores and unclean slough, previous researches show that the red mercuric oxide can effectively treat skin ulcers of mice and ulcers of clinical leprosy patients and plays a certain role in healing infectious wounds. Trichosanthis radix enters lung meridian, and has effects of invigorating qi, strengthening middle warmer, regulating qi flow, and reducing blood sugar. Qing fen can counteract toxic pathogen and heal wound. The three medicines are combined to treat the diabetic foot, so that the effects of drawing out toxin from wounds, resisting infection, accelerating liquefaction and detoxification of necrotic tissues can be achieved.
Further, aiming at the diabetes patients with improved wound surfaces and organic exposure, on the basis of the traditional Chinese medicine composition for treating diabetic foot, the following raw material medicines in parts by weight are added: 9-11 parts of mother-of-pearl, 8-10 parts of teasel root, 10-11 parts of calcined gypsum and 4-6 parts of agilawood.
A Chinese medicinal composition for treating diabetic foot for a patient with improved wound surface and life expectancy, which comprises the following Chinese medicinal components in part by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts, pearl shell 10 parts, dipsacus root 9 parts, calcined gypsum 10.5 parts, and agilawood 5 parts.
For diabetic foot patients with improved wound surface and organically exposed, the nacre contains a large amount of calcium (calcium carbonate), so that the density of capillary vessels at an affected part can be increased, the exudation is reduced, simultaneously, the fiber exudation in a focus is promoted, free radicals are removed, and a good environment is created for epithelial regeneration; the calcined gypsum is a product of calcined gypsum at high temperature, mainly consists of anhydrous calcium sulfate, has the effects of eliminating dampness, promoting granulation, healing sore and stopping bleeding, and can play the roles of astringing and promoting vital function, tonifying liver and kidney, continuing muscles and bones, regulating blood vessels, reducing swelling and producing marrow by being supplemented with the treatment of the agilawood and the teasel root.
The meridian tropism and the effect of each traditional Chinese medicine component in the traditional Chinese medicine composition for treating diabetic foot are as follows:
asarum: pungent and warm. It enters heart, lung and kidney meridians. Has effects of relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging orifice, warming lung, and eliminating phlegm, and can be used for treating wind-cold type common cold, headache, toothache, nasal obstruction, nasal discharge, allergic rhinitis, nasosinusitis, rheumatism paralysis, phlegm retention, asthma, cough, etc.
Pseudo-ginseng: sweet, slightly bitter and warm. It enters liver and stomach meridians. Has the effects of removing blood stasis, stopping bleeding, relieving swelling and relieving pain. Can be used for treating hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, thoracico-abdominal pain, and traumatic injury with swelling and pain.
Dragon's blood: sweet, salty and neutral. It enters heart and liver meridians. Has effects of promoting blood circulation, relieving pain, removing blood stasis, stopping bleeding, promoting granulation, and healing sore. Can be used for treating traumatic injury, heart and abdomen blood stasis and pain, traumatic hemorrhage, unhealed skin and external diseases, etc.
Stiff silkworm: salty, pungent and even. It enters liver, lung and stomach meridians. Has effects of calming endogenous wind, relieving spasm, dispelling pathogenic wind, relieving pain, eliminating phlegm, and resolving hard mass. Can be used for treating crooked liver wind with phlegm, convulsive epilepsy, convulsion, infantile acute infantile convulsion, tetanus, apoplexy, wind-heat headache, conjunctival congestion, pharyngalgia, rubella pruritus, and suppurative parotitis.
Rhizoma arisaematis: bitter, pungent and warm; is toxic. It enters lung, liver and spleen meridians. Has the effects of resolving hard mass and relieving swelling. It is used externally to treat carbuncle, swelling, snake and insect bite.
Stemona root: sweet, bitter and slightly warm. It enters lung meridian. Has the effects of moistening lung, descending qi, relieving cough, killing parasite and killing louse. Can be used for treating chronic cough, pulmonary tuberculosis cough, and cough; it is used for treating head louse, body louse, enterobiasis, and pudendal pruritus. Honey radix Stemonae has effects of moistening lung and relieving cough. Can be used for treating cough due to yin deficiency.
Red lead: pungent taste; heating; it is toxic. Invigorating spleen; the lung meridian. Has the functions of removing toxic substances and pus; removing necrotic tissue and promoting granulation; killing parasites and drying dampness. Can be used for treating furuncle and superficial infection; fistula sinus; goiter and scrofula; mammary abscess of breast cancer; scabies; eczema; syphilis; all stubborn sores are ulcerated for a long time and cannot be healed; dark and dark purple; pus is not discharged smoothly; the preserved beancurd meat is not removed; the new meat is difficult to grow.
Calomel: pungent and cold; is toxic. It enters large intestine and small intestine meridians. Has the effects of killing parasite, removing toxic substance, and healing sore; it has the effects of dispelling phlegm, resolving food stagnation, expelling water and relaxing bowels. Can be used for treating scabies, intractable tinea, ecthyma, syphilis, pyocutaneous disease, and eczema; it is indicated for accumulation of phlegm and saliva, edema and distention, and constipation by oral administration.
Trichosanthes root: sweet, slightly bitter and slightly cold. It enters lung and stomach meridians. Has the effects of clearing heat, purging fire, promoting fluid production, quenching thirst, relieving swelling and expelling pus. Can be used for treating fever polydipsia, lung heat dry cough, internal heat diabetes, pyocutaneous disease and pyogenic infections.
Mother-of-pearl: salty and cold. It enters liver and heart meridians. Has effects of suppressing hyperactive liver, subsiding yang, tranquilizing mind, arresting convulsion, improving eyesight, and removing nebula. Can be used for treating headache, vertigo, palpitation, insomnia, conjunctival congestion, nebula, blurred vision.
Teasel root: bitter and pungent with mild warm nature. It enters liver and kidney meridians. Has effects in nourishing liver and kidney, strengthening muscle and bone, promoting fracture, and preventing metrorrhagia. Can be used for treating deficiency of liver and kidney, soreness of waist and knees, rheumatalgia, traumatic injury, injury of tendons and bones, metrorrhagia, and fetal leakage.
Calcining gypsum: sweet, pungent, astringent and cold. It enters lung and stomach meridians. Has the effects of eliminating dampness, promoting granulation, healing sore and stopping bleeding. Can be used for treating unhealed ulcer, eczema, pruritus, scald due to hot water and fire, and traumatic hemorrhage.
Agilawood: pungent, bitter and slightly warm. It enters spleen, stomach and kidney meridians. Has effects of activating qi-flowing, relieving pain, warming middle-jiao, relieving vomit, and absorbing qi and relieving asthma. Can be used for treating chest and abdomen distention, pain, stomach cold, emesis, singultus, deficiency of the kidney, reversed flow of qi, and dyspnea.
A traditional Chinese medicine composition for treating diabetic foot, the preparation method thereof comprises the following steps:
the method comprises the following steps: cleaning the required medicinal materials, and processing according to the property of the medicine to remove toxin. Weighing herba asari, sanguis Draxonis, Bombyx Batryticatus, rhizoma arisaematis, and radix Stemonae according to formula, soaking, and decocting with water to obtain concentrated decoction.
Step two: weighing the raw materials of the pseudo-ginseng according to the formula, grinding the raw materials into superfine powder, and then performing steaming and baking treatment.
Step three: and (4) blending the concentrated juice treated in the step one with the powder treated in the step two, adding an excipient seasoning paste matrix, and adding oil for decocting.
Step four: continuously stirring to prevent scorching and withering during the decocting process, removing residues, decocting until the water drops become beads, and removing fire to obtain the plaster raw material.
A Chinese medicinal composition for treating diabetic foot for patients with excessive pus volume, unhealed sore and unclean slough, and its preparation method comprises the following steps:
the method comprises the following steps: cleaning the required medicinal materials, and processing according to the property of the medicine to remove toxin. Weighing herba asari, sanguis Draxonis, Bombyx Batryticatus, rhizoma arisaematis, and radix Stemonae according to formula, soaking, and decocting with water to obtain concentrated decoction.
Step two: weighing raw materials of pseudo-ginseng, red mercuric oxide, trichosanthes root, calomel and the like according to a formula, grinding the raw materials into superfine powder, and then steaming and baking the powder.
Step three: and (4) blending the concentrated juice treated in the step one with the powder treated in the step two, adding an excipient seasoning paste matrix, and adding oil for decocting.
Step four: continuously stirring in the decocting process, decocting until the water drops form beads, and removing the fire to obtain the plaster raw material.
A Chinese medicinal composition for treating diabetic foot for patients with wound surface improvement and life mechanism exposure comprises the following steps:
the method comprises the following steps: cleaning the required medicinal materials, and processing according to the property of the medicine to remove toxin. Weighing the raw materials of asarum, dragon's blood, stiff silkworm, rhizoma arisaematis, radix stemonae, teasel root and the like according to the formula, fully soaking, and decocting with water to obtain thick juice.
Step two: weighing Notoginseng radix, Concha Margaritifera, Gypsum Fibrosum Preparatum and lignum Aquilariae Resinatum according to formula, grinding into superfine powder, and steaming and baking.
Step three: and (4) blending the concentrated juice treated in the step one with the powder treated in the step two, adding an excipient seasoning paste matrix, and adding oil for decocting.
Step four: continuously stirring in the decocting process, decocting until the water drops form beads, and removing the fire to obtain the plaster raw material.
The plaster prepared by the method is viscous paste at about 40 ℃, is basically viscous solid at about 36 ℃, does not disperse when being dropped on paper, forms beads when being dropped on water, has easy use when being self-adhered when being heated, and has good lipid solubility of the medicine. It will be condensed when it is cooled, so it is easy to store for a long time, and its medicinal effect is not volatilized. The plaster prepared by the mixture ratio can be prepared into plaster with the thickness of about 10cm multiplied by 12cm and is externally applied to the surface area of a human body.
Compared with the prior art, the invention has the beneficial effects that:
the traditional Chinese medicine composition provided by the invention is reasonable in compatibility, can fully exert the drug effects of the components, ensures the medication safety, and has a remarkable synergistic effect.
Has obvious treatment effect on diabetic feet such as blood vessels blocked below the ankle, neuropathic foot ulcers, nerve-ischemic foot ulcers, lower limb venous disease degenerative ulcers and the like which cannot be solved by western medicine. And can be taken according to the specific conditions of the diabetic foot patients.
For mild diabetic foot patients without obvious wounds, asarum which has the effects of warming lung and dredging orifices and inducing diuresis to alleviate edema is combined; sanguis Draxonis with effects of promoting blood circulation, dispelling blood stasis, stopping bleeding, and relieving pain; stiff silkworm and rhizoma arisaematis with the functions of dispelling wind and extinguishing wind and relieving spasm and pain, panax notoginseng with the functions of relieving swelling and pain and stemona with the functions of killing parasites and relieving itching are prepared into a paste formula which is applied to a wound, the medicine can penetrate deep into blood vessels and channels and collaterals, and deeply penetrate into bones and marrow along with the dredging of the channels and collaterals and the flowing of blood and qi, so that the blood oxygen of abnormal and unconnected tissues can be obtained again, and the clinical symptoms of a patient can be effectively improved.
For diabetic foot patients with large pus volume, unhealing sores and unclean slough, previous researches show that the red mercuric oxide can effectively treat skin ulcers of mice and ulcers of clinical leprosy patients and plays a certain role in healing infectious wounds. Trichosanthis radix enters lung meridian, and has effects of invigorating qi, strengthening middle warmer, regulating qi flow, and reducing blood sugar. Qing fen can counteract toxic pathogen and heal wound. The three medicines are combined to treat the diabetic foot, so that the effects of drawing out toxin from wounds, resisting infection, accelerating liquefaction and detoxification of necrotic tissues can be achieved.
For diabetic foot patients with improved wound surface and organically exposed, the nacre contains a large amount of calcium (calcium carbonate), so that the density of capillary vessels at an affected part can be increased, the exudation is reduced, simultaneously, the fiber exudation in a focus is promoted, free radicals are removed, and a good environment is created for epithelial regeneration; the calcined gypsum is a product of calcined gypsum at high temperature, mainly consists of anhydrous calcium sulfate, has the effects of eliminating dampness, promoting granulation, healing sore and stopping bleeding, and can play the roles of astringing and promoting vital function, tonifying liver and kidney, continuing muscles and bones, regulating blood vessels, reducing swelling and producing marrow by being supplemented with the treatment of the agilawood and the teasel root.
Detailed Description
In order to further understand the objects, structures, features, and functions of the present invention, embodiments 1 and 2 are described in detail below.
Example 1
The invention provides a traditional Chinese medicine composition for treating diabetic foot, which is prepared from the following raw material medicines in parts by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts.
For mild diabetic foot patients without obvious wounds, asarum which has the effects of warming lung and dredging orifices and inducing diuresis to alleviate edema is combined; sanguis Draxonis with effects of promoting blood circulation, dispelling blood stasis, stopping bleeding, and relieving pain; stiff silkworm and rhizoma arisaematis with the functions of dispelling wind and extinguishing wind and relieving spasm and pain, panax notoginseng with the functions of relieving swelling and pain and stemona with the functions of killing parasites and relieving itching are prepared into a paste formula which is applied to a wound, the medicine can penetrate deep into blood vessels and channels and collaterals, and deeply penetrate into bones and marrow along with the dredging of the channels and collaterals and the flowing of blood and qi, so that the blood oxygen of abnormal and unconnected tissues can be obtained again, and the clinical symptoms of a patient can be effectively improved.
A traditional Chinese medicine composition for treating diabetic foot, the preparation method thereof comprises the following steps:
the method comprises the following steps: cleaning the required medicinal materials, and processing according to the property of the medicine to remove toxin. Weighing herba asari, sanguis Draxonis, Bombyx Batryticatus, rhizoma arisaematis, and radix Stemonae according to formula, soaking, and decocting with water to obtain concentrated decoction.
Step two: weighing the raw materials of the pseudo-ginseng according to the formula, grinding the raw materials into superfine powder, and then performing steaming and baking treatment.
Step three: and (4) blending the concentrated juice treated in the step one with the powder treated in the step two, adding an excipient seasoning paste matrix, and adding oil for decocting.
Step four: continuously stirring to prevent scorching and withering during the decocting process, removing residues, decocting until the water drops become beads, and removing fire to obtain the plaster raw material.
Aiming at patients with mild diabetic foot ulceration:
1. the ointment is prepared from Erzhi, male, 73 years old, and 10 more years old in the course of diabetes, wherein the skin at the tail end of the left toe of the second toe of the left foot is broken without obvious exudation, the size of the ulcer is 1.0 x 2.1cm, Wagner grades are 1, and the ointment is prepared from 9.5 parts of asarum, 9.5 parts of pseudo-ginseng, 9.5 parts of dragon's blood, 10 parts of stiff silkworm, 10 parts of rhizoma arisaematis and 10.5 parts of radix stemonae by externally applying to the sore for 7 days, and the broken part is healed.
Zhangzhi, male, 72 years old, with the course of diabetes more than 20 years old, with numbness of the right lower extremities with needling-like pain before 10 years old, with significant plantar region, considering diabetic neuropathy. The skin of the right toe is ulcerated and lingering before 2 years. Ulcer size 0.8 x 1.7cm, Wagner grade 1. The plaster prepared from 9.5 parts of asarum, 9.5 parts of pseudo-ginseng, 9.5 parts of dragon's blood, 10 parts of stiff silkworm, 10 parts of arisaema consanguineum and 10.5 parts of radix stemonae is externally applied to the sore for 5 days, and the ulcer surface is healed.
Example 2
Furthermore, aiming at the diabetes patients with large pus volume, unhealing sores and unclean slough, the traditional Chinese medicine components preferably comprise the following components in percentage by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts, red mercuric oxide 1 part, root of Chinese trichosannthes 9 parts, and calomel 2 parts.
For diabetic foot patients with large pus volume, unhealing sores and unclean slough, previous researches show that the red mercuric oxide can effectively treat skin ulcers of mice and ulcers of clinical leprosy patients and plays a certain role in healing infectious wounds. Trichosanthis radix enters lung meridian, and has effects of invigorating qi, strengthening middle warmer, regulating qi flow, and reducing blood sugar. Qing fen can counteract toxic pathogen and heal wound. The three medicines are combined to treat the diabetic foot, so that the effects of drawing out toxin from wounds, resisting infection, accelerating liquefaction and detoxification of necrotic tissues can be achieved.
A Chinese medicinal composition for treating diabetic foot for patients with excessive pus volume, unhealed sore and unclean slough, and its preparation method comprises the following steps:
the method comprises the following steps: cleaning the required medicinal materials, and processing according to the property of the medicine to remove toxin. Weighing herba asari, sanguis Draxonis, Bombyx Batryticatus, rhizoma arisaematis, and radix Stemonae according to formula, soaking, and decocting with water to obtain concentrated decoction.
Step two: weighing raw materials of pseudo-ginseng, red mercuric oxide, trichosanthes root, calomel and the like according to a formula, grinding the raw materials into superfine powder, and then steaming and baking the powder.
Step three: and (4) blending the concentrated juice treated in the step one with the powder treated in the step two, adding an excipient seasoning paste matrix, and adding oil for decocting.
Step four: continuously stirring in the decocting process, decocting until the water drops form beads, and removing the fire to obtain the plaster raw material.
Further, aiming at the diabetes patients with improved wound surfaces and organic exposure, the traditional Chinese medicine composition preferably comprises the following components in parts by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts, pearl shell 10 parts, dipsacus root 9 parts, calcined gypsum 10.5 parts, and agilawood 5 parts.
For diabetic foot patients with improved wound surface and organically exposed, the nacre contains a large amount of calcium (calcium carbonate), so that the density of capillary vessels at an affected part can be increased, the exudation is reduced, simultaneously, the fiber exudation in a focus is promoted, free radicals are removed, and a good environment is created for epithelial regeneration; the calcined gypsum is a product of calcined gypsum at high temperature, mainly consists of anhydrous calcium sulfate, has the effects of eliminating dampness, promoting granulation, healing sore and stopping bleeding, and can play the roles of astringing and promoting vital function, tonifying liver and kidney, continuing muscles and bones, regulating blood vessels, reducing swelling and producing marrow by being supplemented with the treatment of the agilawood and the teasel root.
A Chinese medicinal composition for treating diabetic foot for patients with wound surface improvement and life mechanism exposure comprises the following steps:
the method comprises the following steps: cleaning the required medicinal materials, and processing according to the property of the medicine to remove toxin. Weighing the raw materials of asarum, dragon's blood, stiff silkworm, rhizoma arisaematis, radix stemonae, teasel root and the like according to the formula, fully soaking, and decocting with water to obtain thick juice.
Step two: weighing Notoginseng radix, Concha Margaritifera, Gypsum Fibrosum Preparatum and lignum Aquilariae Resinatum according to formula, grinding into superfine powder, and steaming and baking.
Step three: and (4) blending the concentrated juice treated in the step one with the powder treated in the step two, adding an excipient seasoning paste matrix, and adding oil for decocting.
Step four: continuously stirring in the decocting process, decocting until the water drops form beads, and removing the fire to obtain the plaster raw material.
For patients with diabetic foot with pus formation:
1. old women, age 81, have a diabetes history of more than 30 years, and have the symptoms that the swelling of the left lower limb is obvious in the last week, the local color is deepened, the foot back is ruptured along with a large amount of seepage, the ruptured part is about 4.0 x 5.0cm, a little bleeding occurs, tenderness is positive, and Wagner grades are 3. 9.5 parts of asarum, 9.5 parts of pseudo-ginseng, 9.5 parts of dragon's blood, 10 parts of stiff silkworm, 10 parts of rhizoma arisaematis and 10.5 parts of radix stemonae are added with 1 part of red mercuric oxide, 9 parts of trichosanthes root and 2 parts of calomel for pus extraction treatment, pus is drained at an affected part after 9 days, at the moment, 9.5 parts of asarum, 9.5 parts of pseudo-ginseng, 9.5 parts of dragon's blood, 10 parts of stiff silkworm, 10 parts of rhizoma arisaematis and 10.5 parts of radix stemonae are sequentially treated for 10 days, the wound surface of the left instep of a patient is reduced to 1.5 x 2.0cm, pain is relieved, and mild edema of toes are selected.
Zhangzhi, male, age 76, diabetes 12 years old, foot skin ulceration 2 years with obvious pain, right foot
Figure 10000235785244
Lateral aspect of the toe 1.5 x 2.3cm wound, third0.8 x 1.2cm wound of toe, 1.4 x 2.0cm wound of outer side of arch of foot, 1.0 x 0.5cm wound of right heel, 1.5 x 0.8cm wound of left heel, a little seepage of part of wound, and part covered with white moss, and positive tenderness. Wagner grades 2-3. The plaster prepared by 9.5 parts of asarum, 9.5 parts of pseudo-ginseng, 9.5 parts of dragon's blood, 10 parts of stiff silkworm, 10 parts of rhizoma arisaematis, 10.5 parts of radix stemonae, 1 part of red mercuric oxide, 9 parts of radix trichosanthis and 2 parts of calomel is externally applied to a sore for 7 days, the exudation of the wound is improved, and a combined medicine prepared by 9.5 parts of asarum, 9.5 parts of pseudo-ginseng, 9.5 parts of dragon's blood, 10 parts of stiff silkworm, 10 parts of radix asparagi, 10.5 parts of radix stemonae, 10 parts of mother-of-pearl, 9 parts of rhizoma arisaematis, 10.5 parts of calcined gypsum and 5 parts of agilawood is selected for treatment for 10 days, the wound surface of both feet of a patient is improved, and the wound surface of the right foot is improved
Figure 10000235813068
0.6X 1.1cm outside the toes, the wound surface separated by fresh tissue parts, 0.7X 1.0cm outside the right arch, 0.4X 0.3cm outside the right heel, 0.6X 0.3cm outside the left heel, obvious granulation tissue proliferation, no obvious liquid seepage and negative tenderness.
Deng, dry gangrene of the left toe and the second toe of women, multiple lesions and ulcerations, Wagner grade 4, and obvious pain. The plaster prepared by 9.5 parts of asarum, 9.5 parts of pseudo-ginseng, 9.5 parts of dragon's blood, 10 parts of stiff silkworm, 10 parts of arisaema cum bile, 10.5 parts of radix stemonae, 1 part of red mercuric oxide, 9 parts of trichosanthes root and 2 parts of calomel is externally applied to a sore for 10 days, and then the compound medicine prepared by 9.5 parts of asarum, 9.5 parts of pseudo-ginseng, 9.5 parts of dragon's blood, 10 parts of stiff silkworm, 10 parts of arisaema cum bile, 10.5 parts of radix stemonae, 10 parts of mother-of-pearl, 9 parts of teasel root, 10.5 parts of calcined gypsum and 5 parts of agilawood is used for 10 days, the periphery of the gangrene on the toe is changed from original pale of ischemia to ruddy, which indicates that blood supply is formed and pain of an affected part is relieved.
The present invention has been described in relation to the above embodiments, which are only exemplary of the implementation of the present invention. It should be noted that the disclosed embodiments do not limit the scope of the invention. Rather, it is intended that all such modifications and variations be included within the spirit and scope of this invention.

Claims (9)

1. The traditional Chinese medicine composition for treating diabetic foot is characterized by being prepared from the following raw material medicines in parts by weight: 8-12 parts of asarum, 8-11 parts of pseudo-ginseng, 9-10 parts of dragon's blood, 9-10 parts of stiff silkworm, 9-11 parts of rhizoma arisaematis and 10-11 parts of radix stemonae.
2. The traditional Chinese medicine composition for treating diabetic foot according to claim 1, which is prepared from the following raw materials in parts by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts.
3. A traditional Chinese medicine composition for treating diabetic foot for patients with large pus volume, unhealed sore and unclean slough, which is characterized in that the following raw material medicines in parts by weight are added on the basis of claim 1: 0-2 parts of red mercuric oxide, 8-10 parts of trichosanthes root and 1-3 parts of calomel.
4. The traditional Chinese medicine composition for treating diabetic foot for patients with large pus volume, unhealed sore and unhealthy slough according to claim 3, which is prepared from the following raw material medicines in parts by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts, red mercuric oxide 1 part, root of Chinese trichosannthes 9 parts, and calomel 2 parts.
5. A traditional Chinese medicine composition for treating diabetic foot for a patient with improved wound surface and mechanical manifestation is characterized in that the traditional Chinese medicine composition is prepared by adding the following raw material medicines in parts by weight on the basis of claim 1: 9-11 parts of mother-of-pearl, 8-10 parts of teasel root, 10-11 parts of calcined gypsum and 4-6 parts of agilawood.
6. The traditional Chinese medicine composition for treating diabetic foot of a patient with wound healing and life-promoting exposure according to claim 5, which is prepared from the following raw material medicines in parts by weight: asarum herb 9.5 parts, notoginseng 9.5 parts, dragon's blood resin 9.5 parts, batryticated silkworm 10 parts, arisaema tuber 10 parts, stemona root 10.5 parts, pearl shell 10 parts, dipsacus root 9 parts, calcined gypsum 10.5 parts, and agilawood 5 parts.
7. The method for preparing the traditional Chinese medicine composition according to any one of claims 1 or 2, wherein the preparation method comprises the following steps:
the method comprises the following steps: weighing herba asari, sanguis Draxonis, Bombyx Batryticatus, rhizoma arisaematis, and radix Stemonae according to formula, soaking, and decocting with water to obtain concentrated decoction;
step two: weighing the raw materials of the pseudo-ginseng according to the formula, grinding the raw materials into superfine powder, and then performing steaming and baking treatment;
step three: blending the thick juice treated in the step one with the powder treated in the step two, adding a plaster matrix, and adding oil for decocting;
step four: continuously stirring in the decocting process, decocting until the water drops form beads, and removing the fire to obtain the plaster raw material.
8. The method for preparing the traditional Chinese medicine composition according to any one of claims 3 or 4, wherein the preparation method comprises the following steps:
the method comprises the following steps: weighing herba asari, sanguis Draxonis, Bombyx Batryticatus, rhizoma arisaematis, and radix Stemonae according to formula, soaking, and decocting with water to obtain concentrated decoction;
step two: weighing raw materials of pseudo-ginseng, red mercuric oxide, trichosanthes root, calomel and the like according to a formula, grinding the raw materials into superfine powder, and then steaming and baking the powder;
step three: blending the thick juice treated in the step one with the powder treated in the step two, adding a plaster matrix, and adding oil for decocting;
step four: continuously stirring in the decocting process, decocting until the water drops form beads, and removing the fire to obtain the plaster raw material.
9. The method for preparing the traditional Chinese medicine composition according to any one of claims 5 or 6, wherein the preparation method comprises the following steps:
the method comprises the following steps: weighing herba asari, sanguis Draxonis, Bombyx Batryticatus, rhizoma arisaematis, radix Stemonae and radix Dipsaci according to formula, soaking, and decocting with water to obtain concentrated juice;
step two: weighing Notoginseng radix, Concha Margaritifera, Gypsum Fibrosum Preparatum and lignum Aquilariae Resinatum raw materials according to formula, grinding into superfine powder, and steaming and baking;
step three: blending the thick juice treated in the step one with the powder treated in the step two, adding a plaster matrix, and adding oil for decocting;
step four: continuously stirring in the decocting process, decocting until the water drops form beads, and removing the fire to obtain the plaster raw material.
CN202110537897.1A 2021-05-18 2021-05-18 Traditional Chinese medicine composition for treating diabetic foot and preparation method thereof Pending CN113304230A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110537897.1A CN113304230A (en) 2021-05-18 2021-05-18 Traditional Chinese medicine composition for treating diabetic foot and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110537897.1A CN113304230A (en) 2021-05-18 2021-05-18 Traditional Chinese medicine composition for treating diabetic foot and preparation method thereof

Publications (1)

Publication Number Publication Date
CN113304230A true CN113304230A (en) 2021-08-27

Family

ID=77373558

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110537897.1A Pending CN113304230A (en) 2021-05-18 2021-05-18 Traditional Chinese medicine composition for treating diabetic foot and preparation method thereof

Country Status (1)

Country Link
CN (1) CN113304230A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103784684A (en) * 2014-02-25 2014-05-14 牛正华 Xuemaian blood glucose lowering capsule with therapeutic action on diabetes
CN108904660A (en) * 2018-08-31 2018-11-30 徐高阳 A kind of liniment for treating bedsore and diabetes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103784684A (en) * 2014-02-25 2014-05-14 牛正华 Xuemaian blood glucose lowering capsule with therapeutic action on diabetes
CN108904660A (en) * 2018-08-31 2018-11-30 徐高阳 A kind of liniment for treating bedsore and diabetes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘鹏等: "中药内外合用治疗糖尿病足部溃疡46例", 《光明中医》 *
贾慧等: "溃疡油治疗糖尿病足溃疡临床疗效观察", 《北京中医药大学学报(中医临床版)》 *

Similar Documents

Publication Publication Date Title
CN106620539A (en) External ointment for treating skin diseases as well as preparation method and application thereof
CN103961587A (en) Traditional Chinese medicinal preparation for treating radiographic contrast nephropathy and preparation method thereof
CN109745429A (en) A kind of Chinese medicine and preparation method thereof for treating the long disunion of wound
CN103977367A (en) Traditional Chinese medicament for treating qi-stagnation blood-aggregation type bedsore and preparation method thereof
CN113304230A (en) Traditional Chinese medicine composition for treating diabetic foot and preparation method thereof
CN103417781A (en) Traditional Chinese medicine for treating surgical wounds
CN103393943A (en) Traditional Chinese medicine composition for treating sequela of cerebral infarction
CN104274662A (en) Itching treating medicine
CN103055013A (en) Combination drug of curing rash and burn and preparation method thereof
CN111544523A (en) Traditional Chinese medicine composition for treating skin ulceration and application thereof
CN111265566A (en) A Chinese medicinal composition for treating fracture, and its preparation method
CN104623304A (en) Lotion for treating chronic skin ulcer caused by damp-heat and toxicity accumulation and preparation method of lotion
CN104524107A (en) Chinese patent medicine for wind cold damp impediment symptom
CN103721067A (en) Traditional Chinese medicine composition for diabetes and foot care
CN103877557B (en) A kind of Chinese medicine ointment and preparation method for the treatment of tinea unguium
CN103356870A (en) Traditional Chinese medicinal preparation for treating postpartum hypogalactia, and preparation method thereof
CN107496567A (en) A kind of Chinese medicine preparation for treating diabetic foot and preparation method thereof
CN1579497A (en) Traditional Chinese medicinal preparation for treating iternal-external ulcer and its preparation method
CN101502611B (en) Medicament for treating cancer and preparation method thereof
CN105816737A (en) Foot bath formula for treating insomnia
CN105327290A (en) Traditional Chinese medicine for external use for treating diabetic gangrene and preparation method thereof
CN105362675A (en) Emulsifiable paste for treating plasmacellular mastitis and preparation method thereof
CN105055978A (en) Pharmaceutical composition for treating alcoholic distention
CN104474452A (en) Medicine for treating blood coagulation and toxin accumulating bedsore and preparation method of medicine
CN105362944A (en) Traditional Chinese medicine ointment for treating orthopedics sprain and contusion

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20210827

RJ01 Rejection of invention patent application after publication