CN113286587A - 用于治疗iv型胶原病的联苯磺酰胺化合物 - Google Patents

用于治疗iv型胶原病的联苯磺酰胺化合物 Download PDF

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Publication number
CN113286587A
CN113286587A CN201980079773.4A CN201980079773A CN113286587A CN 113286587 A CN113286587 A CN 113286587A CN 201980079773 A CN201980079773 A CN 201980079773A CN 113286587 A CN113286587 A CN 113286587A
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China
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subject
pharmaceutical composition
compound
pharmaceutically acceptable
acceptable salt
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Pending
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CN201980079773.4A
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English (en)
Chinese (zh)
Inventor
R·科梅尔斯
C·詹金森
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Traville Treatment Co
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Traville Treatment Co
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=68318947&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN113286587(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Traville Treatment Co filed Critical Traville Treatment Co
Publication of CN113286587A publication Critical patent/CN113286587A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201980079773.4A 2018-10-04 2019-10-03 用于治疗iv型胶原病的联苯磺酰胺化合物 Pending CN113286587A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862741270P 2018-10-04 2018-10-04
US62/741,270 2018-10-04
US201962853904P 2019-05-29 2019-05-29
US62/853,904 2019-05-29
US201962894559P 2019-08-30 2019-08-30
US62/894,559 2019-08-30
PCT/US2019/054559 WO2020072814A1 (en) 2018-10-04 2019-10-03 Biphenyl sulfonamide compounds for the treatment of type iv collagen diseases

Publications (1)

Publication Number Publication Date
CN113286587A true CN113286587A (zh) 2021-08-20

Family

ID=68318947

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980079773.4A Pending CN113286587A (zh) 2018-10-04 2019-10-03 用于治疗iv型胶原病的联苯磺酰胺化合物

Country Status (13)

Country Link
US (1) US11207299B2 (cg-RX-API-DMAC10.html)
EP (1) EP3860594B1 (cg-RX-API-DMAC10.html)
JP (2) JP7524167B2 (cg-RX-API-DMAC10.html)
KR (1) KR102902972B1 (cg-RX-API-DMAC10.html)
CN (1) CN113286587A (cg-RX-API-DMAC10.html)
AU (1) AU2019354784B2 (cg-RX-API-DMAC10.html)
BR (1) BR112021006132A2 (cg-RX-API-DMAC10.html)
CA (1) CA3114434A1 (cg-RX-API-DMAC10.html)
ES (1) ES3057657T3 (cg-RX-API-DMAC10.html)
IL (2) IL327175A (cg-RX-API-DMAC10.html)
MA (1) MA53817A (cg-RX-API-DMAC10.html)
MX (1) MX2021003606A (cg-RX-API-DMAC10.html)
WO (1) WO2020072814A1 (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019530713A (ja) 2016-10-13 2019-10-24 レトロフィン， インコーポレイテッド 腎臓疾患または障害を処置するためのビフェニルスルホンアミド化合物
WO2022246200A1 (en) * 2021-05-21 2022-11-24 Travere Therapeutics, Inc. Methods of treating kidney diseases or disorders
WO2022266370A1 (en) * 2021-06-17 2022-12-22 Aria Pharmaceuticals, Inc. Sparsentan for treating idiopathic pulmonary fibrosis
JP2025183466A (ja) * 2022-11-11 2025-12-17 株式会社アークメディスン 化合物、エンドセリンａ受容体拮抗剤、アンジオテンシンｉｉタイプ１受容体拮抗剤及び医薬組成物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107106637A (zh) * 2014-08-21 2017-08-29 康德生物医疗技术公司 用于疾病预防和治疗的方法和组合物
WO2018071784A1 (en) * 2016-10-13 2018-04-19 Retrophin, Inc. Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID26984A (id) 1998-07-06 2001-02-22 Bristol Myers Squibb Co Senyawa-senyawa sulfonamida sebagai antagonis reseptor angiotensin endotelin ganda
US6638937B2 (en) 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
WO2001044239A2 (en) 1999-12-15 2001-06-21 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
WO2010114801A1 (en) 2009-03-31 2010-10-07 Ligand Pharmaceuticals Inc. Oral formulations of diphenylsulfonamide endothelin and angiotensin ii receptor agonists to treat elevated blood pressure and diabetic nephropathy
WO2010135350A2 (en) 2009-05-20 2010-11-25 Pharmacopeia, Llc Biphenyl intermediate compounds and methods for the preparation of a dual angiotensin ii and endothelin a receptor antagonist
US9719981B2 (en) 2012-08-17 2017-08-01 Father Flanagan's Boys' Home RAC1 inhibitors for the treatment of alport glomerular disease
CN109982718A (zh) * 2016-09-19 2019-07-05 阿托恩波罗斯生命科学 基于环糊精的聚合物、方法、组合物及其应用
BR112021012226A2 (pt) 2018-12-21 2021-09-08 Travere Therapeutics, Inc. Composições de esparsentano amorfo

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107106637A (zh) * 2014-08-21 2017-08-29 康德生物医疗技术公司 用于疾病预防和治疗的方法和组合物
WO2018071784A1 (en) * 2016-10-13 2018-04-19 Retrophin, Inc. Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice", HEARING RESEARCH, vol. 341, 21 August 2016 (2016-08-21), pages 100 - 108 *
FRANK.T.L VAN DER LOOP，ET AL,: "Autosomal dominant Alport syndrome caused by a COL4A3 splice site mutation", KIDNEKIDNEY INTERNATIONAL, vol. 58, no. 5, 1 November 2000 (2000-11-01), pages 1870 - 1875, XP055653101, DOI: 10.1111/j.1523-1755.2000.00358.x *

Also Published As

Publication number Publication date
CA3114434A1 (en) 2020-04-09
MX2021003606A (es) 2021-08-16
ES3057657T3 (en) 2026-03-03
KR102902972B1 (ko) 2025-12-22
KR20210081338A (ko) 2021-07-01
AU2019354784A1 (en) 2021-04-15
US11207299B2 (en) 2021-12-28
IL281965B2 (en) 2026-08-01
AU2019354784B2 (en) 2025-07-10
EP3860594A1 (en) 2021-08-11
JP2022514152A (ja) 2022-02-10
MA53817A (fr) 2021-08-11
JP2024133735A (ja) 2024-10-02
IL281965A (en) 2021-05-31
US20200147050A1 (en) 2020-05-14
WO2020072814A1 (en) 2020-04-09
BR112021006132A2 (pt) 2021-07-20
EP3860594B1 (en) 2025-10-01
JP7524167B2 (ja) 2024-07-29
IL281965B1 (en) 2026-04-01
IL327175A (en) 2026-05-01

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