CN113286581A - 用于治疗视网膜疾病的眼内或者口服给药用药物组合物 - Google Patents

用于治疗视网膜疾病的眼内或者口服给药用药物组合物 Download PDF

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CN113286581A
CN113286581A CN202080008302.7A CN202080008302A CN113286581A CN 113286581 A CN113286581 A CN 113286581A CN 202080008302 A CN202080008302 A CN 202080008302A CN 113286581 A CN113286581 A CN 113286581A
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retinal
disease
compound
methyl
pharmaceutical composition
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Chinese (zh)
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山田健一
进藤早纪
石田南人
山本启一
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Fuso Pharmaceutical Industries Ltd
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Fuso Pharmaceutical Industries Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K9/0048—Eye, e.g. artificial tears
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/47—Quinolines; Isoquinolines
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CN202080008302.7A 2019-01-09 2020-01-09 用于治疗视网膜疾病的眼内或者口服给药用药物组合物 Pending CN113286581A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019-001979 2019-01-09
JP2019001979 2019-01-09
PCT/JP2020/000538 WO2020145364A1 (ja) 2019-01-09 2020-01-09 網膜疾患の治療のための眼内または経口投与用医薬組成物

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CN113286581A true CN113286581A (zh) 2021-08-20

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CN202080008302.7A Pending CN113286581A (zh) 2019-01-09 2020-01-09 用于治疗视网膜疾病的眼内或者口服给药用药物组合物

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US (1) US20220096410A1 (https=)
EP (1) EP3919052A4 (https=)
JP (2) JPWO2020145364A1 (https=)
CN (1) CN113286581A (https=)
AU (1) AU2020205535B2 (https=)
CA (1) CA3126333A1 (https=)
WO (1) WO2020145364A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3148598A1 (en) 2019-07-30 2021-02-04 Mayo Foundation For Medical Education And Research Compounds and methods for treating fibrotic pathologies
US20240043396A1 (en) * 2021-01-29 2024-02-08 Mayo Foundation For Medical Education And Research Methods of treating ocular fibrotic pathologies
CN113082031A (zh) * 2021-03-09 2021-07-09 温州医科大学附属眼视光医院 一种多巴胺d1和d2受体非选择性激动剂在作为制备治疗眼部病理性血管新生药物的应用
US20230398095A1 (en) * 2022-06-10 2023-12-14 Ahmad Alkayali Therapeutic agent for treatment of age-related macular degeneration

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050137147A1 (en) * 2003-12-22 2005-06-23 Alcon, Inc. Agents for treatment of diabetic retinopathy and drusen formation in macular degeneration
CN102245179A (zh) * 2008-10-24 2011-11-16 谢菲尔德大学 神经病症的治疗剂
WO2015029948A1 (ja) * 2013-08-26 2015-03-05 リンク・ジェノミクス株式会社 網膜色素上皮の障害を原因とする網膜疾患の予防または治療剤
CN107582605A (zh) * 2016-07-07 2018-01-16 萨尔瓦特实验室股份有限公司 眼用组合物
CN111033257A (zh) * 2017-07-06 2020-04-17 扶桑药品工业株式会社 脂质过氧化诱发性疾病的治疗药物及其筛选方法

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FR2771010B1 (fr) * 1997-11-19 2003-08-15 Adir Utilisation d'une combinaison d'un inhibiteur de l'enzyme de conversion de l'angiotensine et d'un diuretique pour le traitement des desordres microcirculatoires
WO2009129497A2 (en) 2008-04-18 2009-10-22 Arizona Board Of Regents, A Body Corp. Of The State Of Arizona, Acting For And On Behalf Of The University Of Arizona Methods and compositions for treating and identifying compounds to treat age-related macular degeneration
US9018202B2 (en) * 2010-12-03 2015-04-28 Allergan, Inc. Methods for treating diseases of the retina
JP2017218384A (ja) * 2016-06-03 2017-12-14 国立大学法人京都大学 網膜疾患の予防または治療のための医薬組成物
US11123411B2 (en) * 2016-12-08 2021-09-21 Gary E. Borodic Method of treating macular degeneration using botulinum toxin-based pharmaceuticals

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050137147A1 (en) * 2003-12-22 2005-06-23 Alcon, Inc. Agents for treatment of diabetic retinopathy and drusen formation in macular degeneration
CN102245179A (zh) * 2008-10-24 2011-11-16 谢菲尔德大学 神经病症的治疗剂
WO2015029948A1 (ja) * 2013-08-26 2015-03-05 リンク・ジェノミクス株式会社 網膜色素上皮の障害を原因とする網膜疾患の予防または治療剤
CN107582605A (zh) * 2016-07-07 2018-01-16 萨尔瓦特实验室股份有限公司 眼用组合物
CN111033257A (zh) * 2017-07-06 2020-04-17 扶桑药品工业株式会社 脂质过氧化诱发性疾病的治疗药物及其筛选方法

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WO2020145364A1 (ja) 2020-07-16
US20220096410A1 (en) 2022-03-31
EP3919052A1 (en) 2021-12-08
EP3919052A4 (en) 2022-10-05
JP2024144702A (ja) 2024-10-11
CA3126333A1 (en) 2020-07-16
JPWO2020145364A1 (https=) 2020-07-16
AU2020205535B2 (en) 2025-04-10
AU2020205535A1 (en) 2021-08-26

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