CN113274621A

CN113274621A - Medical micro guide wire

Info

Publication number: CN113274621A
Application number: CN202110713442.0A
Authority: CN
Inventors: 郭力友; 王宇伦; 夏洁
Original assignee: Suzhou Zhongtian Medical Device Technology Co ltd
Current assignee: Suzhou Zhongtian Medical Device Technology Co ltd
Priority date: 2021-06-25
Filing date: 2021-06-25
Publication date: 2021-08-20

Abstract

The invention relates to the technical field of medical instruments and discloses a medical micro guide wire. The medical micro-guide wire comprises a flexible core wire and a supporting outer wall, wherein the flexible core wire comprises a supporting section and a flexible section, the flexible section is positioned close to the far end side of the flexible core wire, the supporting section is positioned close to the near end side of the flexible core wire, and the flexible section can flexibly penetrate through a blood vessel; the supporting outer wall is wrapped on the supporting section of the flexible core wire and is used for providing supporting strength for the supporting section; the flexible core wire and the supporting outer wall are coaxial and are integrally formed. The invention realizes that the near end has supporting performance and the far end has soft performance, and the flexible core wire and the supporting outer wall are coaxial and integrally formed, and the flexible core wire and the supporting outer wall are not provided with connecting parts, so the problem of fracture cannot be caused, and the safety of the medical micro-guide wire is improved.

Description

Medical micro guide wire

Technical Field

The invention relates to the technical field of medical instruments, in particular to a medical micro guide wire.

Background

Stroke, commonly known as stroke, includes ischemic stroke (also called cerebral infarction) and hemorrhagic stroke (including hemorrhage of parenchyma of the brain, hemorrhage of the ventricles of the brain and subarachnoid hemorrhage), which are diseases of necrosis of brain cells and tissues. The ischemic stroke is an important reason for causing the disability and death of adults in the world, the life of the population of China is greatly prolonged along with the improvement of living standard, the aging degree is increased, meanwhile, the incidence rate of the ischemic stroke is higher and higher due to the increase of obese people and diabetic people, and the ischemic stroke becomes one of the main diseases damaging the lives of the Chinese people. The development of the nerve intervention operation is promoted by the increase of patients with cerebrovascular diseases, the consumption of nerve intervention instruments is greatly increased, but most of the nerve intervention instruments depend on import and are expensive.

Generally, conventional methods for treating ischemic stroke include thrombectomy, stenting, balloon dilatation, carotid stenting, etc., but these conventional surgical methods all use a guide wire product. The common micro-guide wire products on the market at present can generate a fracture phenomenon in use, endanger the life of a patient and cannot achieve an ideal use effect.

The use requirements of the guide wire are that the guide wire is supported at the near end and flexible at the far end, but the products on the market can keep the near end supported at present and the far end is not flexible enough; the flexible connection structure can keep the far end flexible, the near end has insufficient support performance, the stainless steel material can ensure the support performance, the nickel-titanium material can ensure the flexible performance, an intermediate connection process is adopted in order to meet different performance requirements of two ends, but the connection part has weak strength and is easy to break, the fracture phenomenon threatens the life of a patient, and the connection part cannot meet good torsion resistance.

Based on this, a medical micro-guide wire is needed to solve the above existing problems.

Disclosure of Invention

Based on the above, the invention aims to provide a medical micro guide wire, which realizes that the proximal end has a supporting performance and the distal end has a soft performance, and moreover, the flexible core wire and the supporting outer wall are coaxially and integrally formed, and the flexible core wire and the supporting outer wall are not provided with a connecting part, so that the problem of fracture cannot be caused, and the safety of the medical micro guide wire is improved.

In order to achieve the purpose, the invention adopts the following technical scheme:

a medical micro-guidewire, comprising:

the flexible core wire comprises a support section and a flexible section, the flexible section is positioned close to the far end side of the flexible core wire, the support section is positioned close to the near end side of the flexible core wire, and the flexible section can flexibly penetrate through the blood vessel;

the supporting outer wall is coated on the supporting section of the flexible core wire and is used for providing supporting strength for the supporting section;

the flexible core wire and the supporting outer wall are coaxial and are integrally formed.

As a preferred technical scheme of the medical micro guide wire, the flexible core wire is made of nickel-titanium alloy, and the supporting outer wall is made of stainless steel.

As a preferable technical scheme of the medical micro guide wire, the flexible section is a reducing section, and the outer diameter of the reducing section is gradually reduced along the direction departing from the support section.

As a preferred technical scheme of the medical micro-guide wire, the medical micro-guide wire further comprises a wire winding assembly, wherein the wire winding assembly is arranged on the flexible section of the flexible core wire, and the wire winding assembly has developing property.

As a preferred technical scheme of medical little seal wire, the wire winding subassembly is including developing the wire winding and supporting the wire winding, develop the wire winding set up in the distal end of flexible section just is fixed in support the outer wall, support the distal end of wire winding connect in develop the wire winding, support the near-end of wire winding and be fixed in support the outer wall.

As a preferred technical scheme of the medical micro-guide wire, one end of the supporting winding wire is connected with the developing winding wire, and the other end of the supporting winding wire is connected with the supporting outer wall.

As a preferred technical scheme of the medical micro-guide wire, the developing winding wire is made of platinum group alloy, gold or tantalum alloy; the support winding wire is made of stainless steel.

As a preferred technical scheme of the medical micro guide wire, the flexible core wire and the support outer wall are integrally formed through a fusion casting process, a rolling process or a drawing process.

As a preferable technical scheme of the medical micro-guide wire, the outer side wall of the medical micro-guide wire is coated with a hydrophilic coating and/or a PTFE coating.

As a preferable technical scheme of the medical micro-guide wire, the outer side wall of the wire winding component is coated with a hydrophilic coating.

The invention has the beneficial effects that:

when this medical little seal wire moves in the blood vessel, in the blood vessel can be worn to locate by the flexible section of flexible core silk, the compliance of medical little seal wire distal end is guaranteed to the flexible section of flexible core silk to the angle can be stereotyped, realizes that the selectivity gets into appointed intravascular, and when flexible section touched the vascular wall simultaneously, can not harm the blood vessel yet and make the blood vessel break, supports the outer wall and can provide the holding power to the near-end of this medical little seal wire. The medical micro guide wire has the advantages that the near end has supporting performance, the far end has soft performance, the flexible core wire and the supporting outer wall are coaxial and integrally formed, and the flexible core wire and the supporting outer wall are not provided with connecting parts, so that the problem of breakage is avoided, and the safety of the medical micro guide wire is improved.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments of the present invention will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the contents of the embodiments of the present invention and the drawings without creative efforts.

FIG. 1 is a schematic structural diagram of a medical micro-guidewire provided by an embodiment of the present invention passing through a blood vessel;

FIG. 2 is a schematic structural diagram of a medical micro-guidewire provided by an embodiment of the invention;

FIG. 3 is a cross-sectional view of a support segment of a flexible core wire provided in accordance with an embodiment of the present invention;

fig. 4 is a schematic structural view of the installation of the wire winding assembly according to the embodiment of the present invention.

The figures are labeled as follows:

100. a medical micro-guide wire; 200. a thrombotic lesion site; 300. a blood vessel;

1. a flexible core filament; 11. a support section; 12. a flexible section; 121. a first constant diameter pole segment; 122. a second constant diameter pole segment; 123. a third constant diameter pole segment; 124. a tapered rod section; 2. a support outer wall; 3. a wire winding assembly; 31. developing and winding; 32. supporting the filament winding.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.

In the description of the present invention, unless expressly stated or limited otherwise, the terms "connected," "connected," and "fixed" are to be construed broadly, e.g., as meaning permanently connected, removably connected, or integral to one another; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

In the present invention, unless otherwise expressly stated or limited, "above" or "below" a first feature means that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact with each other via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.

In the description of the present embodiment, the terms "upper", "lower", "left", "right", and the like are used based on the orientations and positional relationships shown in the drawings only for convenience of description and simplification of operation, and do not indicate or imply that the referred device or element must have a specific orientation, be configured and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used only for descriptive purposes and are not intended to have a special meaning.

In this embodiment, "distal" refers to the end of the component remote from the operator, and "proximal" refers to the end of the component near the operator.

To solve the above problem, as shown in fig. 1 to 4, the present embodiment provides a medical micro-guidewire 100 for a blood vessel 300, wherein the medical micro-guidewire 100 comprises a flexible core wire 1 and a supporting outer wall 2.

Specifically, as shown in fig. 1-3, the flexible core wire 1 includes a support section 11 and a flexible section 12, the flexible section 12 is located near the distal end side of the flexible core wire 1, the support section 11 is located near the proximal end side of the flexible core wire 1, and the flexible section 12 can be flexibly threaded into the blood vessel 300; the supporting outer wall 2 is coated on the supporting section 11 of the flexible core wire 1, and the supporting outer wall 2 is used for providing supporting strength for the supporting section 11; the flexible core wire 1 and the supporting outer wall 2 are coaxial and are integrally formed. Preferably, the flexible core wire 1 is made of nickel titanium alloy, the nickel titanium alloy has flexibility and shape memory effect, when the flexible core wire 1 passes through the tortuous blood vessel 300, the flexible core wire 1 can be deformed to pass through the blood vessel 300, and after the flexible core wire 1 passes through the tortuous blood vessel 300, the flexible core wire 1 recovers the self-memory shape at the blood temperature; the material of the supporting outer wall 2 is stainless steel, and the stainless steel has supporting performance. The flexible core wire 1 and the supporting outer wall 2 are integrally formed through a casting process, a rolling process or a drawing process.

This little seal wire 100 of medical use when removing in blood vessel 300, the flexibility section 12 of flexible core silk 1 can wear to locate in blood vessel 300, the compliance of the little seal wire 100 distal end of medical use is guaranteed to the flexibility section 12 of flexible core silk 1, and flexible section 12 can design the angle, realize in the appointed blood vessel 300 of selective entering, when flexible section 12 touches the vascular wall simultaneously, also can not harm blood vessel 300 and make blood vessel 300 break, support outer wall 2 can provide the holding power to this little seal wire 100's of medical use near-end. This medical little seal wire 100 has realized that the near-end has the support performance, and the distal end has the compliance, and moreover, flexible core silk 1 and support outer wall 2 are coaxial and integrated into one piece, and the two does not set up the position of connection, consequently can not produce cracked problem, has improved medical little seal wire 100's security.

Preferably, the flexible section 12 is a diameter-variable section, the outer diameter of the diameter-variable section is gradually reduced along the direction departing from the support section 11, and the arrangement of the diameter-variable section improves the flexibility of the flexible section 12, so that the medical micro-guide wire 100 can move in the blood vessel 300 conveniently. In this embodiment, the variable-diameter section is processed by a grinding process, and the variable-diameter section includes a first constant-diameter rod section 121, a second constant-diameter rod section 122 and a third constant-diameter rod section 123 which are connected in sequence, where the first constant-diameter rod section 121 is located at the distal end of the flexible section 12, the outer diameter of the first constant-diameter rod section 121 is smaller than that of the second constant-diameter rod section 122, the outer diameter of the second constant-diameter rod section 122 is smaller than that of the third constant-diameter rod section 123, the outer diameter of the third constant-diameter rod section 123 is smaller than that of the support section 11, and the first constant-diameter rod section 121 and the second constant-diameter rod section 122, the second constant-diameter rod section 122 and the third constant-diameter rod section 123, and the third constant-diameter rod section 123 and the support section 11 are respectively transitionally connected by the tapered rod section 124 processed by the grinding process, so as to prevent a step structure from damaging the blood vessel 300.

Further preferably, as shown in fig. 4, the medical micro-guidewire 100 further comprises a wire winding assembly 3, the wire winding assembly 3 is disposed on the flexible segment 12 of the flexible core wire 1 and fixed on the supporting outer wall 2, and the wire winding assembly 3 has developing property. The wire winding assembly 3 is fixed to the flexible core wire 1 by bonding, welding or mechanical riveting. When the medical micro-wire 100 is inserted into the blood vessel 300, an operator can detect the position of the wire winding assembly 3 through the developing instrument, and then judge the position of the distal end of the medical micro-wire 100 in the blood vessel 300. It should be noted that, because the flexible section 12 is a diameter-variable section, and the outer diameter of the diameter-variable section is smaller than the outer diameter of the supporting outer wall 2, after the wire-winding assembly 3 is disposed on the flexible section 12, the outer diameter of the wire-winding assembly 3 is not larger than the outer diameter of the supporting outer wall 2, so as to ensure that the outer surface of the medical micro-guidewire 100 is as smooth as possible, and prevent the blood vessel 300 from being scratched.

Preferably, the wire-winding assembly 3 comprises a developing wire-winding 31 and a supporting wire-winding 32, the developing wire-winding 31 is disposed at the distal end of the flexible segment 12, the distal end of the supporting wire-winding 32 is connected to the developing wire-winding 31, and the proximal end of the supporting wire-winding 32 is fixed to the supporting outer wall 2. The visualization winding wire 31 has visualization properties, the support winding wire 32 is used for supporting the winding wire assembly 3, the support winding wire 32 also provides a support force for the proximal end of the flexible segment 12 of the flexible core wire 1, the support force is enough to enable the flexible segment 12 of the flexible core wire 1 to smoothly pass through the thrombus lesion 200, and the visualization winding wire 31 which is arranged on the flexible segment 12 and is soft enough can reduce irritation and injury as much as possible when passing through the thrombus lesion 200 and possibly touching the blood vessel wall and can also smoothly pass through the tortuous blood vessel 300.

In this embodiment, the developing winding wire 31 is made of platinum group alloy, gold or tantalum alloy; the support wire wrap 32 is made of stainless steel. The stainless steel support winding wire 32 has a low production cost compared to the developing winding wire 31 made of platinum group alloy, gold, tantalum alloy, or the like, and the support winding wire 32 can reduce the production cost of the winding assembly 3.

Of course, in other embodiments, the wire-winding assembly 3 may also be entirely composed of the developing wire-winding 31, and the proximal end of the developing wire-winding 31 may be directly fixed to the supporting outer wall 2.

In this embodiment, one end of the supporting winding wire 32 is connected to the developing winding wire 31, and the other end is connected to the supporting outer wall 2 to fix the winding wire assembly 3, and the connection manner may be a mechanical connection manner such as bonding, welding, or riveting.

Preferably, the outer sidewall of the medical micro-guidewire 100 is coated with a hydrophilic coating and/or a PTFE coating. Specifically, the hydrophilic coating and the PTFE coating both have a lubricating effect, and the distal end of the medical micro-guidewire 100 is coated with the hydrophilic coating to achieve lubrication; the proximal end of the medical micro-guide wire 100 is coated with the hydrophilic coating or the PTFE coating, so that lubrication is realized, the hydrophilic coating and the PTFE coating improve the lubricity of the outer side wall of the medical micro-guide wire 100, the medical micro-guide wire 100 is convenient to move in the blood vessel 300, and the damage to the blood vessel wall caused by insufficient lubricity is prevented. It is further preferred that the outer sidewall of the wire-winding assembly 3 is coated with a hydrophilic coating to reduce the production cost relative to the overall coating, and at the same time, to improve the lubricity of the distal end of the medical micro-wire 100 to facilitate the movement of the distal end of the medical micro-wire 100 within the blood vessel 300.

It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.

Claims

1. A medical micro-guidewire, comprising:

the flexible core wire (1), the flexible core wire (1) comprises a support section (11) and a flexible section (12), the flexible section (12) is positioned close to the distal end side of the flexible core wire (1), the support section (11) is positioned close to the proximal end side of the flexible core wire (1), and the flexible section (12) can be flexibly arranged in a blood vessel (300) in a penetrating way;

a supporting outer wall (2), wherein the supporting outer wall (2) is wrapped on the supporting section (11) of the flexible core wire (1), and the supporting outer wall (2) is used for providing supporting strength for the supporting section (11);

the flexible core wire (1) and the supporting outer wall (2) are coaxial and are integrally formed.

2. The medical micro guide wire according to claim 1, wherein the flexible core wire (1) is made of nitinol, and the support outer wall (2) is made of stainless steel.

3. The medical micro-guidewire according to claim 1, wherein the flexible section (12) is a tapered section having an outer diameter that gradually decreases in a direction away from the support section (11).

4. The medical micro guidewire according to claim 1, further comprising a wire winding assembly (3), wherein the wire winding assembly (3) is disposed on the flexible segment (12) of the flexible core wire (1) and fixed to the support outer wall (2), and the wire winding assembly (3) has visualization properties.

5. The medical micro-guidewire according to claim 4, wherein the wire-winding assembly (3) comprises a visualization wire-winding (31) and a support wire-winding (32), the visualization wire-winding (31) is disposed at the distal end of the flexible section (12), the distal end of the support wire-winding (32) is connected to the visualization wire-winding (31), and the proximal end of the support wire-winding (32) is fixed to the support outer wall (2).

6. The medical micro-guidewire according to claim 5, wherein the support wire wrap (32) is connected to the visualization wire wrap (31) at one end and to the support outer wall (2) at the other end.

7. The medical micro-guidewire according to claim 5, wherein the developing winding wire (31) is made of platinum group alloy, gold or tantalum alloy; the supporting winding wire (32) is made of stainless steel.

8. The medical micro guidewire according to claim 1, wherein the flexible core wire (1) is integrally formed with the support outer wall (2) by a fusion casting process, a rolling process or a drawing process.

9. The medical micro-guidewire of claim 1, wherein the outer side wall of the medical micro-guidewire is coated with a hydrophilic coating and/or a PTFE coating.

10. The medical micro-guidewire according to claim 4, wherein the outer side wall of the wire winding component (3) is coated with a hydrophilic coating.