CN113274426A

CN113274426A - Formula and preparation process of cassia twig and poria cocos pills for inhibiting tumor metastasis

Info

Publication number: CN113274426A
Application number: CN202110786038.6A
Authority: CN
Inventors: 韩立; 杜瑞娟; 丁生晨; 王旭; 李颖利; 郭晓娟; 卞华; 齐培
Original assignee: Nanyang Institute of Technology
Current assignee: Nanyang Institute of Technology
Priority date: 2021-07-12
Filing date: 2021-07-12
Publication date: 2021-08-20

Abstract

The invention relates to the technical field of cassia twig and poria cocos pills, and particularly discloses a formula and a preparation process of a cassia twig and poria cocos pill for inhibiting tumor metastasis; the formula of the cassia twig-poria cocos pill for inhibiting tumor metastasis comprises 70-100 parts of cassia twig powder, 85-105 parts of poria cocos powder, 18-25 parts of astragalus membranaceus powder, 22-28 parts of sculellaria barbata powder and 55-70 parts of refined honey, wherein the preparation device comprises a machine base, a raw material mixing device, an extrusion pill making device and a rolling dryer; the invention discloses a cassia twig and tuckahoe pill which adopts cassia twig powder and tuckahoe powder as main components and adds proper amount of astragalus powder and barbat skullcap powder as auxiliary materials, and the prepared cassia twig and tuckahoe pill has certain function in inhibiting tumor metastasis through the mutual compatibility between the main material and the auxiliary materials; meanwhile, the disclosed device can sequentially realize the effects of quantitative feeding, material mixing, pelleting, drying and the like, has various functions, and has compact structure, small occupied area and excellent use effect in the preparation of the cassia twig and poria cocos pills.

Description

Formula and preparation process of cassia twig and poria cocos pills for inhibiting tumor metastasis

Technical Field

The invention relates to the technical field of cassia twig and poria cocos pills, and particularly discloses a formula and a preparation process of a cassia twig and poria cocos pill for inhibiting tumor metastasis.

Background

The cassia twig and tuckahoe pill is one of the commonly used Chinese patent medicines for gynecology and has the efficacies of activating blood, removing blood stasis and eliminating mass. The traditional Chinese medicine composition is mainly used for treating dysmenorrhea, amenorrhea and irregular menstruation caused by obstruction of collaterals by blood stasis of women, unclean postpartum lochiorrhea, hysteromyoma, chronic pelvic inflammatory disease, pelvic blood stasis syndrome, endometriosis, ovarian pain cyst and the like, but relevant research reports are few in the aspect of the effect of inhibiting tumor metastasis and the like. In addition, the fresh cassia twig and poria cocos pills are all prepared through production lines consisting of a mixer, a pill making machine and drying equipment respectively, the whole production line equipment occupies a large area, the prepared pills are heated and dried in a drying box through a movable conveyor belt in the conventional drying equipment, and the surfaces of the pills cannot be synchronously dried in an all-round mode in the process that the pills move along with the conveyor belt.

For example, utility model application No. 201720125689.X just discloses a pellet pill machine heat radiation structure, in the pharmaceutical raw materials gets into the pay-off section of thick bamboo from the feeding section of thick bamboo, motor drive screw axis rotated, and the screw axis drives the pharmaceutical raw materials in the pay-off section of thick bamboo and moves to the open end of pay-off section of thick bamboo. The medicine raw materials enter the conical extrusion cylinder from the open end of the feeding cylinder, and under the extrusion of the inner surface of the conical extrusion cylinder, the medicine raw materials form a strip shape and enter the rotating cylinder. The strip-shaped medicine raw materials are pressed into pills after flowing out of the material rotating cylinder and are rolled into the pills, the pills fall on the conveying belt, the conveying belt drives the pills to move, the pills firstly move to the position below the hot air blower, hot air blown out of the hot air blower is in contact with the pills to dry the pills, the dried high-temperature pills move to the position below the cold air blower under the driving of the conveying belt, and cold air blown out of the cold air blower is in contact with the pills to cool the pills. Although the heat dissipation structure of the pill making machine disclosed by the utility model discloses the pill making and drying processes, the prepared pills are irregular and are not in spherical particles, and the drying machine is the existing conveyor belt drying equipment, so that the drying effect of the medicines in the conveying process is poor; meanwhile, when the device is used, a corresponding mixer is required to be equipped to fully stir various raw material powders. Therefore, aiming at the defects of the prior pill making machine, the design of the cassia twig and poria cocos pill production device for inhibiting tumor metastasis, which has multiple functions, can prepare pills with uniform shapes and spherical particles and can effectively dry the surfaces of the pills, is a technical problem to be solved.

Disclosure of Invention

Aiming at the defects of the prior pill making machine, the invention designs the cassia twig and poria cocos pill production device which has multiple functions, can prepare pills with uniform shapes and spherical particles and can effectively dry the surfaces of the pills and is used for inhibiting tumor metastasis.

The invention is realized by the following technical scheme:

the formula of the cassia twig and poria cocos pill for inhibiting tumor metastasis comprises the following components in parts by weight: 70-100 parts of cassia twig powder, 85-105 parts of poria cocos powder, 18-25 parts of astragalus membranaceus powder, 22-28 parts of sculellaria barbata powder and 55-70 parts of refined honey.

A preparation process of the cassia twig and poria cocos pills for inhibiting tumor metastasis comprises the following steps:

1) weighing the components in parts by weight, and sieving the powder raw materials with a 120-mesh sieve for later use;

2) putting the weighed and sieved powder into a mixer, stirring for 10-20 min, adding the refined honey, continuously stirring for 30-35 min, and putting into a pill making machine to prepare pills;

3) and (3) sending the prepared pills into a drying device for hot air drying, putting the dried pills into a coating machine for coating treatment, and drying and cooling the coated pills to obtain the traditional Chinese medicine composition.

Preferably, the hot air temperature for drying the pills in the drying device is 75-80 ℃.

A preparation device for preparing the cassia twig and poria cocos pills for inhibiting tumor metastasis comprises a machine base, a raw material mixing device, a pill extruding and making device and a rolling dryer, wherein the pill extruding and making device is fixedly arranged on the upper surface of the machine base;

the raw material mixing device comprises a mixing cylinder, the lower end of the mixing cylinder is connected with a blanking pipe, a material valve is arranged on the blanking pipe, the upper end of the outer side of the circumference of the mixing cylinder is uniformly connected with a plurality of spiral conveying machines, the upper surface of the outer end of each spiral conveying machine is connected with a raw material hopper, a stirring motor is arranged in the circle center of the upper surface of the mixing cylinder, and the end part of an output shaft of the stirring motor, which extends into the inner cavity of the mixing cylinder, is connected with a stirring frame;

the extrusion pill-making device comprises an extrusion case, the upper surface of the extrusion case is provided with a material receiving groove arranged right below a blanking pipe, the interior of the extrusion case is provided with a horizontally arranged cylindrical extrusion inner cavity, the outer end of the cylindrical extrusion inner cavity is connected with an extrusion head, the outer surface of the extrusion case positioned at the opposite side of the extrusion head is provided with an extrusion motor, the end part of an output shaft of the extrusion motor, which extends into the cylindrical extrusion inner cavity, is connected with an extrusion spiral blade, the outer end of the extrusion head is connected with an L-shaped extrusion shaping circular pipe, the interior of the extrusion case positioned below the extrusion head is provided with a motor installation inner cavity, the motor installation inner cavity is internally provided with a driving motor, the outer surface of the extrusion case positioned at the outer side of the motor installation inner cavity is provided with a gear box, two first gears which are symmetrical and meshed in front and back are arranged in the gear box, and the output shaft of the driving motor extends into the gear box to be connected with the inner end surface of one of the first gears, the outer end surfaces of the two first gears are connected with rotating shafts extending out of the gear box, the outer end of each rotating shaft is connected with a rotating disc, the two rotating discs are symmetrical, the circumferential surfaces of the two rotating discs are mutually attached, an L-shaped extrusion shaping circular tube is arranged right above the joint of the two rotating discs, the outer circumferential surface of each rotating disc is uniformly provided with a plurality of hemispherical forming grooves, and a material guide roller path which is arranged in a downward inclination manner is arranged right below the rotating discs;

the rolling dryer comprises a base, an arc-shaped rotating groove is formed in the upper surface of the base, an arc-shaped rolling pan is arranged in the arc-shaped rotating groove, the lower end of a guide roller path is arranged right above the arc-shaped rolling pan, the left end and the right end of the lower surface of the arc-shaped rolling pan are both connected with arc-shaped racks, the lower end of the arc-shaped rolling pan is rotatably connected with an arc-shaped bottom plate, the arc-shaped bottom plate enables the arc-shaped bottom plate and the inner wall of the arc-shaped rolling pan to be in the same arc shape through a torsional spring arranged at a rotating joint, a magnetic strip is arranged on the lower surface of the arc-shaped bottom plate, a discharging channel is arranged below the arc-shaped rotating groove, a discharging conveyor is arranged on the bottom wall of the discharging channel, electromagnetic suckers facing the magnetic strip are fixedly arranged above the discharging conveyor, rotating rods are arranged in the bases on the left side and the right side of the discharging channel, a second gear extending into the arc-shaped rotating groove and meshed with the arc-shaped racks is arranged on each rotating rod, the both ends all are provided with the rotation motor that is connected with the dwang about the leading flank of base, and the top that is located the base is provided with the stoving cover, and the side of base is provided with the air heater, and the air-out end of air heater is connected with the hot-blast main that stretches into the inside upper end of stoving cover, and the exhaust vent that faces the setting of arc roll pot is seted up to the lower surface of hot-blast main.

As the further setting of above-mentioned scheme, the agitator frame includes vertical puddler, and two sets of crushing blades that are circumference and evenly arrange about the upper end of puddler is connected with are connected with a plurality of groups puddler on the puddler that is located crushing blade below to the lower extreme of puddler is connected with the narrow spiral pay-off leaf about wide.

As the further setting of above-mentioned scheme, the outer end of every group puddler is connected with the flitch of scraping that laminates mutually with the compounding section of thick bamboo inner wall jointly.

As a further arrangement of the scheme, the spiral material conveyer comprises a transversely arranged feeding cylinder, the outer end face of the feeding cylinder is connected with a variable frequency motor, and the end part of an output shaft of the variable frequency motor, which extends into the feeding cylinder, is connected with a packing auger blade.

As a further arrangement of the scheme, 12-36 hemispherical forming grooves are formed in the outer circular surface of each rotary table.

As the further arrangement of the scheme, the number of the arc-shaped racks arranged at each end of the lower surface of the arc-shaped rolling pot is two, the arc-shaped racks are symmetrically arranged from front to back, and the number of the gears arranged on each rotating rod is also two and is respectively meshed with each arc-shaped rack.

As a further arrangement of the scheme, the hot air pipe comprises a main branch pipe, a plurality of vertical branch pipes are connected to the main branch pipe at intervals, and air outlet holes are arranged on the lower surface of each branch pipe at intervals.

Has the advantages that:

1) the invention discloses a cassia twig-tuckahoe pill which takes cassia twig powder and tuckahoe powder as main components and is added with proper amount of astragalus powder and sculellaria barbata powder as auxiliary materials, and the prepared cassia twig-tuckahoe pill has certain effect on inhibiting tumor metastasis through the mutual compatibility between the main materials and the auxiliary materials.

2) The preparation device of the cassia twig and poria cocos pills disclosed by the invention is integrated equipment, the whole equipment can sequentially realize the effects of quantitative feeding, mixing, pelleting, drying and the like, the functions are various, and the whole equipment is compact in structure, small in occupied area and excellent in use effect in the preparation of the cassia twig and poria cocos pills.

3) When the rolling dryer disclosed by the invention dries prepared pills, the whole arc-shaped rolling pot can rotate in an arc-shaped rotating groove in a reciprocating manner through the meshing action between the gear and the arc-shaped rack, so that the pills in the arc-shaped rolling pot are in a continuous rolling state during drying, and the pills can be dried in all directions; meanwhile, the pills are in a continuous rolling state in the drying process, so that the pills are gradually deformed into uniform spherical particles, and the using effect is very excellent.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.

Fig. 1 is a preparation flow chart of the cassia twig and poria cocos pill disclosed by the invention.

FIG. 2 is a schematic perspective view of the present invention;

FIG. 3 is a schematic perspective view of a raw material mixing apparatus according to the present invention;

FIG. 4 is a schematic perspective view of a stirring motor and a stirring frame according to the present invention;

FIG. 5 is a schematic perspective view of an extrusion pelletizing apparatus according to the present invention;

FIG. 6 is a schematic view of the internal plan structure of the extrusion pelletizing apparatus according to the invention;

FIG. 7 is a schematic perspective view of a base according to the present invention;

FIG. 8 is a schematic view of a first angle structure of the arc rolling pan, the gear and the like in the present invention;

FIG. 9 is a schematic view of a second angle structure of the arc rolling pan, the gear and the like according to the present invention;

FIG. 10 is a schematic view showing an inner plan structure of a rolling dryer according to the present invention;

FIG. 11 is a schematic perspective view of a hot air blower and a hot air duct according to the present invention;

wherein:

1-raw material mixing device, 101-mixing barrel, 102-blanking pipe, 103-material valve, 104-spiral conveyer, 1041-feeding barrel, 1042-variable frequency motor, 105-raw material hopper, 106-stirring motor, 107-stirring frame, 1071-stirring rod, 1072-crushing blade, 1073-stirring rod, 1074-spiral feeding blade, 1075-scraping plate;

2-extrusion pelleting device, 201-extrusion machine box, 202-material receiving groove, 203-cylindrical extrusion inner cavity, 204-extrusion head, 205-extrusion motor, 206-extrusion spiral blade, 207-L-shaped extrusion shaping circular tube, 208-motor installation inner cavity, 209-driving motor, 210-gear box, 211-first gear, 212-rotating shaft, 213-rotating disc, 214-hemispherical forming groove and 215-material guide roller path;

3-rolling dryer, 301-base, 302-arc rotating groove, 303-arc rolling pan, 304-arc rack, 305-arc bottom plate, 306-magnetic stripe, 307-blanking channel, 308-blanking channel, 3081-raised baffle ring, 309-electromagnetic chuck, 310-rotating rod, 311-second gear, 312-rotating motor, 313-drying cover, 314-hot air blower, 315-hot air pipe, 3151-main branch pipe, 3152-branch pipe;

4-machine base, 5-control switch.

Detailed Description

In order to make the technical solutions better understood by those skilled in the art, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only partial embodiments of the present application, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

It should be noted that the terms "first," "second," and the like in the description and claims of this application and in the drawings described above are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It should be understood that the data so used may be interchanged under appropriate circumstances such that embodiments of the application described herein may be used. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The formulation, preparation process and apparatus of Guizhi Fuling Wan for inhibiting tumor metastasis disclosed in the present application will be described in detail with reference to the accompanying drawings 1-11.

Example 1

The embodiment 1 discloses a formula of a cassia twig-poria cocos pill for inhibiting tumor metastasis, wherein the formula comprises 86g of cassia twig powder, 95g of poria cocos powder, 22g of astragalus membranaceus powder, 26g of sculellaria barbata powder and 64g of refined honey.

Also discloses a preparation process of the cassia twig and poria cocos pill for inhibiting tumor metastasis, as shown in figure 1, the preparation process comprises the following steps:

2) putting the weighed and sieved powder into a mixer, stirring for 16min, adding the refined honey, continuously stirring for 34min, and putting into a pill making machine to prepare pills;

Wherein the hot air temperature for drying the pills in the drying device is 76 ℃.

Example 2

The embodiment 2 discloses a formula of a cassia twig-poria cocos pill for inhibiting tumor metastasis, wherein the formula comprises 92g of cassia twig powder, 88g of poria cocos powder, 24g of astragalus membranaceus powder, 23g of sculellaria barbata powder and 62g of refined honey.

A preparation process of the cassia twig and poria cocos pill for inhibiting tumor metastasis is shown in figure 1 and comprises the following steps:

2) putting the weighed and sieved powder into a mixer, stirring for 18min, adding the refined honey, continuously stirring for 35min, and putting into a pill making machine to prepare pills;

Wherein the hot air temperature for drying the pills in the drying device is 80 ℃.

The invention also discloses a preparation device for preparing the cassia twig and poria cocos pills, which is specifically described with reference to the attached drawings 1-10.

A preparation device for preparing the cassia twig and poria cocos pills refers to the attached drawing 2, the main components of the preparation device comprise a machine base 4, a raw material mixing device 1, an extrusion pill making device 2 and a rolling dryer 3, the extrusion pill making device 2 is fixedly installed on the upper surface of the machine base 4, a control switch 5 is arranged on the machine base 4, the raw material mixing device 1 is arranged right above the extrusion pill making device 2, and the rolling dryer 3 is arranged beside the machine base 4.

Referring to fig. 3 and fig. 4, wherein, the raw material mixing device 1 includes a mixing cylinder 101, a discharging pipe 102 is connected to the lower end of the mixing cylinder 101, a material valve 103 is disposed on the discharging pipe 102, a plurality of spiral feeders 104 are uniformly connected to the upper end of the outer circumference of the mixing cylinder 101, a raw material hopper 105 is connected to the upper surface of the outer end of the spiral feeder 104, wherein the spiral feeder 104 includes a transversely arranged feeding cylinder 1041, a variable frequency motor 1042 is connected to the outer end surface of the feeding cylinder 1041, and a packing auger blade is connected to the end of the variable frequency motor 1042 extending into the feeding cylinder 1041. A stirring motor 106 is arranged at the center of the upper surface of the mixing barrel 101, and the end of the output shaft of the stirring motor 106 extending into the inner cavity of the mixing barrel 101 is connected with a stirring frame 107. This agitator 107 includes a vertical puddler 1071 during specific setting, and two sets of crushing blade 1072 that are circumference and evenly arrange about the upper end of puddler 1071 is connected with, is connected with a plurality of puddlers 1073 on the puddler 1071 that is located crushing blade 1072 below to the lower extreme of puddler 1071 is connected with the narrow spiral feeding leaf 1074 under wide. And the outer end of each group of the stirring rods 1073 is connected with a scraper plate 1075 which is attached to the inner wall of the mixing cylinder 101. The raw material mixing device 1 with the above arrangement can quantitatively feed each raw material through the spiral material conveyer 104, and fully stir the raw material through the stirring frame 107 after feeding the raw material, and the scraper 1075 can effectively prevent the paste from being stuck on the inner wall of the mixing cylinder 101.

Referring to fig. 5 and fig. 6, the extrusion pelletizing device 2 includes an extruder casing 201, and a material receiving groove 202 disposed right below the blanking pipe 102 is formed on an upper surface of the extruder casing 201. A horizontally arranged cylindrical extrusion inner cavity 203 is formed in the extrusion casing 201, and the lower end of the material receiving groove 202 is communicated with the cylindrical extrusion inner cavity 203. An extrusion head 204 is connected to the outer end of the cylindrical extrusion inner cavity 203, an extrusion motor 205 is installed on the outer surface of the extrusion case 201 opposite to the extrusion head 204, an extrusion spiral blade 206 is connected to the end of the output shaft of the extrusion motor 205 extending into the cylindrical extrusion inner cavity 203, and an L-shaped extrusion shaping circular tube 207 is connected to the outer end of the extrusion head 204. The mixed paste can be extruded from the L-shaped extrusion molding round tube 207 as a soft muddy strand by rotating the extrusion screw 206 by a motor.

Meanwhile, a motor installation inner cavity 208 is arranged inside the extruder case 201 below the extrusion head 204, a driving motor 209 is arranged in the motor installation inner cavity 208, a gear box 210 is arranged on the outer surface of the extruder case 201 outside the motor installation inner cavity 208, and two gears 211 which are symmetrical in the front-back direction and meshed with each other are arranged in the gear box 210. An output shaft of a driving motor 209 extends into a gear box 210 to be connected with an inner end face of one gear 211, outer end faces of the two gears 211 are connected with rotating shafts 212 extending out of the gear box 210, the outer end of each rotating shaft 212 is connected with a rotating disc 213, the two rotating discs 213 are symmetrical and are arranged in a mutually-jointed mode in a circumferential surface mode, and an L-shaped extrusion shaping circular tube 207 is arranged right above a mutually-jointed position of the two rotating discs 213. The outer circular surface of each rotary table 213 is uniformly provided with a plurality of hemispherical forming grooves 214, the number of the hemispherical forming grooves 215 formed in the outer circular surface of each rotary table 213 is 12-36 during specific setting, the two rotary tables 213 can reversely and synchronously rotate under the transmission action of a motor and a gear, and linear materials extruded from the L-shaped extrusion shaping circular tube 207 can be pressed into spherical small granular pills through the two symmetrical hemispherical forming grooves 215 during the reverse and synchronous rotation process. And a guide chute 215 is provided just below the turntable 213 and is inclined downward so that the spherical pills can roll down along the guide chute 215.

Referring to fig. 7, 8, 9 and 10, the rolling dryer 3 includes a base 301, an arc-shaped rotating groove 302 is formed on the upper surface of the base 301, an arc-shaped rolling pan 303 is disposed in the arc-shaped rotating groove 302, the lower end of the material guiding roller path 216 is disposed right above the arc-shaped rolling pan 303, and the falling spherical pills can fall into the arc-shaped rolling pan 303. Arc-shaped racks 304 are connected to the left and right ends of the lower surface of the arc-shaped rolling pan 303, rotating rods 310 are arranged at the left and right ends of the base 301, a gear 311 which stretches into the arc-shaped rotating groove 302 and is meshed with the arc-shaped racks 304 is arranged on each rotating rod 310, and rotating motors 312 which are connected with the rotating rods 310 are arranged at the left and right ends of the front side surface of the base 301. The arc-shaped racks 304 arranged at each end of the lower surface of the arc-shaped rolling pan 303 are two when the arc-shaped rolling pan is specifically arranged, the arc-shaped racks are symmetrically arranged front and back, the gears 311 arranged on each rotating rod 310 are also two and are respectively meshed with each arc-shaped rack 304, the rotating rods 310 are driven by the motor to rotate positively and reversely, and then the arc-shaped rolling pan 303 can rotate in the arc-shaped rotating groove 302 in a reciprocating swing mode through the meshing action between the gears 311 and the arc-shaped racks 304.

Simultaneously, the lower extreme at arc rolling pot 303 rotates and is connected with arc bottom plate 305, arc bottom plate 305 makes arc bottom plate 305 and the inner wall of arc rolling pot 303 be located same arc through the torsional spring that rotates the junction setting, thereby with its bottom seal setting, still be provided with magnetic stripe 306 at the lower surface of arc bottom plate 305 simultaneously, unloading passageway 307 has been seted up to the below of arc rotation groove 302, be provided with ejection of compact conveyer 308 on the diapire of unloading passageway 307, the both ends of the defeated material belt in this ejection of compact conveyer 308 all are provided with protruding fender ring 3081. An electromagnetic suction cup 309 facing the magnetic strip 306 is fixedly arranged above the discharging conveyor 308, and after drying is completed, the electromagnetic suction cup 309 is electrified to generate an adsorption effect on the magnetic strip 306, so that the arc-shaped bottom plate 305 rotates downwards, and dried pills are discharged onto the discharging conveyor 308.

Referring to fig. 10 and 11, a drying cover 313 is disposed above the base 301, an air heater 314 is disposed beside the base 301, an air outlet end of the air heater 314 is connected to a hot air pipe 315 extending into an upper end of the drying cover 313, and an air outlet facing the arc-shaped rolling pan 303 is disposed on a lower surface of the hot air pipe 315. When the hot air pipe 315 is specifically arranged, the hot air pipe 315 includes a main branch pipe 3151, a plurality of vertical branch pipes 3152 are connected to the main branch pipe 3151 at intervals, and air outlets are arranged at intervals on the lower surface of each branch pipe 3152. When the pills roll in the arc-shaped rolling pot 303, the pills can be quickly dried in all directions through hot air fed into the hot air pipe 315, and the dried pills can be discharged into the discharging conveyor 308 to be discharged.

The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The formula of the cassia twig and poria cocos pill for inhibiting tumor metastasis is characterized by comprising the following components in parts by weight: 70-100 parts of cassia twig powder, 85-105 parts of poria cocos powder, 18-25 parts of astragalus membranaceus powder, 22-28 parts of sculellaria barbata powder and 55-70 parts of refined honey.

2. A process for preparing the Guizhi Fuling Wan for inhibiting tumor metastasis according to claim 1, comprising the steps of:

3. The process for preparing Guizhi Fuling Wan for inhibiting tumor metastasis according to claim 1, wherein the temperature of hot air for drying the pill in the drying device is 75-80 ℃.

4. A preparation device for preparing the cassia twig and poria cocos pills for inhibiting tumor metastasis as claimed in claim 1, is characterized by comprising a base (4), a raw material mixing device (1), an extrusion pill making device (2) and a rolling dryer (3), wherein the extrusion pill making device (2) is fixedly installed on the upper surface of the base (4), the base (4) is provided with a control switch (5), the raw material mixing device (1) is arranged right above the extrusion pill making device (2), and the rolling dryer (3) is arranged beside the base (4);

the raw material mixing device (1) comprises a mixing cylinder (101), the lower end of the mixing cylinder (101) is connected with a blanking pipe (102), a material valve (103) is arranged on the blanking pipe (102), the upper end of the outer side of the circumference of the mixing cylinder (101) is uniformly connected with a plurality of spiral material conveyors (104), the upper surface of the outer end of each spiral material conveyor (104) is connected with a raw material hopper (105), the circle center of the upper surface of the mixing cylinder (101) is provided with a stirring motor (106), and the end part of an output shaft of each stirring motor (106), which extends into the inner cavity of the mixing cylinder (101), is connected with a stirring frame (107);

the extrusion pelleting device (2) comprises an extrusion case (201), a material receiving groove (202) arranged right below a blanking pipe (102) is formed in the upper surface of the extrusion case (201), a horizontally arranged cylindrical extrusion inner cavity (203) is formed in the extrusion case (201), an extrusion head (204) is connected to the outer end of the cylindrical extrusion inner cavity (203), an extrusion motor (205) is installed on the outer surface of the extrusion case (201) opposite to the extrusion head (204), an end part of an output shaft of the extrusion motor (205) extending into the cylindrical extrusion inner cavity (203) is connected with an extrusion spiral blade (206), an L-shaped extrusion shaping circular pipe (207) is connected to the outer end of the extrusion head (204), a motor installation inner cavity (208) is formed in the extrusion case (201) below the extrusion head (204), a driving motor (209) is arranged in the motor installation inner cavity (208), and a gear box (210) is arranged on the outer surface of the extrusion case (201) outside the motor installation inner cavity (208), two first gears (211) which are symmetrical front and back and meshed are arranged in the gear box (210), an output shaft of a driving motor (209) extends into the gear box (210) to be connected with the inner end face of one first gear (211), the outer end faces of the two first gears (211) are connected with rotating shafts (212) extending out of the gear box (210), the outer end of each rotating shaft (212) is connected with a rotating disc (213), the two rotating discs (213) are symmetrical, the circumferential faces of the two rotating discs are attached to each other, an L-shaped extrusion shaping circular tube (207) is arranged right above the attachment position of the two rotating discs (213), a plurality of hemispherical shaping grooves (214) are uniformly formed in the outer circumferential face of each rotating disc (213), and a material guide raceway (215) which is arranged downwards in a downward inclining mode is arranged right below the rotating discs (213);

the rolling dryer (3) comprises a base (301), an arc-shaped rotating groove (302) is formed in the upper surface of the base (301), an arc-shaped rolling pot (303) is arranged in the arc-shaped rotating groove (302), the lower end of a material guide roller path (216) is arranged right above the arc-shaped rolling pot (303), arc-shaped racks (304) are connected to the left end and the right end of the lower surface of the arc-shaped rolling pot (303), an arc-shaped bottom plate (305) is connected to the lower end of the arc-shaped rolling pot (303) in a rotating mode, the arc-shaped bottom plate (305) enables the arc-shaped bottom plate (305) and the inner wall of the arc-shaped rolling pot (303) to be in the same arc shape through a torsion spring arranged at the rotating connection position, a magnetic strip (306) is arranged on the lower surface of the arc-shaped bottom plate (305), a discharging channel (307) is formed below the arc-shaped rotating groove (302), a discharging conveyor (308) is arranged on the bottom wall of the discharging channel (307), an electromagnetic suction cup (309) facing the magnetic strip (306) is fixedly arranged above the discharging conveyor (308), the automatic feeding device is characterized in that rotating rods (310) are arranged in the bases (301) on the left side and the right side of the feeding channel (307), each rotating rod (310) is provided with a second gear (311) which stretches into the arc-shaped rotating groove (302) and is meshed with the arc-shaped rack (304), the left end and the right end of the front side of each base (301) are provided with rotating motors (312) which are connected with the rotating rods (310), a drying cover (313) is arranged above the bases (301), an air heater (314) is arranged beside the bases (301), an air outlet end of the air heater (314) is connected with a hot air pipe (315) which stretches into the upper end of the interior of the drying cover (313), and an air outlet hole which is opposite to the arc-shaped rolling pot (303) is formed in the lower surface of the hot air pipe (315).

5. The apparatus for preparing Guizhi Fuling Wan for inhibiting tumor metastasis according to claim 4, wherein the stirring frame (107) comprises a vertical stirring rod (1071), the upper end of the stirring rod (1071) is connected with two sets of upper and lower crushing blades (1072) uniformly arranged in the circumferential direction, the stirring rod (1071) located under the crushing blades (1072) is connected with a plurality of sets of stirring rods (1073), and the lower end of the stirring rod (1071) is connected with a spiral feeding blade (1074) with a wide upper part and a narrow lower part.

6. The apparatus for preparing Guizhi Fuling Wan to inhibit tumor metastasis according to claim 4, wherein the outer end of each set of stirring rods (1073) is commonly connected with a scraper (1075) attached to the inner wall of the mixing barrel (101).

7. The device for preparing the cassia twig and poria cocos pills for inhibiting tumor metastasis according to claim 4, wherein the spiral conveyor (104) comprises a transversely arranged feeding cylinder (1041), the outer end surface of the feeding cylinder (1041) is connected with a variable frequency motor (1042), and the end part of the output shaft of the variable frequency motor (1042) extending into the feeding cylinder (1041) is connected with a packing auger blade.

8. The apparatus for preparing Guizhi Fuling Wan for inhibiting tumor metastasis according to claim 4, wherein the number of the hemispherical forming grooves (215) formed on the outer circumferential surface of each turntable (213) is 12 to 36.

9. The apparatus for preparing Guizhi Fuling Wan to inhibit tumor metastasis according to claim 4, wherein two arc-shaped racks (304) are provided at each end of the lower surface of the arc-shaped rolling pan (303), and are symmetrically arranged in front and rear, and two second gears (311) are provided on each rotating rod (310), and are engaged with each arc-shaped rack (304), respectively.

10. The apparatus for preparing Guizhi Fuling Wan to inhibit tumor metastasis according to claim 4, wherein the hot air duct (315) comprises a main branch duct (3151), a plurality of vertical branch ducts (3152) are connected to the main branch duct (3151) at intervals, and air outlet holes are provided at intervals on the lower surface of each branch duct (3152).