CN113274378A - ω-3五烯酸组合物及使用方法 - Google Patents

ω-3五烯酸组合物及使用方法 Download PDF

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Publication number
CN113274378A
CN113274378A CN202110585483.6A CN202110585483A CN113274378A CN 113274378 A CN113274378 A CN 113274378A CN 202110585483 A CN202110585483 A CN 202110585483A CN 113274378 A CN113274378 A CN 113274378A
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CN
China
Prior art keywords
dpa
dha
epa
omega
per day
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Pending
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CN202110585483.6A
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English (en)
Chinese (zh)
Inventor
乔治·博博泰斯
阿卜杜勒·阿齐兹·法齐
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Matinas Biopharma Inc
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Matinas Biopharma Inc
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Publication of CN113274378A publication Critical patent/CN113274378A/zh
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B20/00—Preservation of edible oils or fats
    • A23B20/30—Preservation of other edible oils or fats, e.g. shortenings or cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B5/00—Preserving by using additives, e.g. anti-oxidants
    • C11B5/0007—Organic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Botany (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
CN202110585483.6A 2012-12-06 2013-12-06 ω-3五烯酸组合物及使用方法 Pending CN113274378A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261734331P 2012-12-06 2012-12-06
US61/734,331 2012-12-06
US201361780948P 2013-03-13 2013-03-13
US61/780,948 2013-03-13
CN201380063980.3A CN104937103A (zh) 2012-12-06 2013-12-06 ω-3五烯酸组合物及使用方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380063980.3A Division CN104937103A (zh) 2012-12-06 2013-12-06 ω-3五烯酸组合物及使用方法

Publications (1)

Publication Number Publication Date
CN113274378A true CN113274378A (zh) 2021-08-20

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ID=50884050

Family Applications (4)

Application Number Title Priority Date Filing Date
CN202110585483.6A Pending CN113274378A (zh) 2012-12-06 2013-12-06 ω-3五烯酸组合物及使用方法
CN202010984870.2A Pending CN112107570A (zh) 2012-12-06 2013-12-06 施用包含二十二碳五烯酸的组合物的方法
CN201380064003.5A Pending CN104902888A (zh) 2012-12-06 2013-12-06 施用包含二十二碳五烯酸的组合物的方法
CN201380063980.3A Pending CN104937103A (zh) 2012-12-06 2013-12-06 ω-3五烯酸组合物及使用方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN202010984870.2A Pending CN112107570A (zh) 2012-12-06 2013-12-06 施用包含二十二碳五烯酸的组合物的方法
CN201380064003.5A Pending CN104902888A (zh) 2012-12-06 2013-12-06 施用包含二十二碳五烯酸的组合物的方法
CN201380063980.3A Pending CN104937103A (zh) 2012-12-06 2013-12-06 ω-3五烯酸组合物及使用方法

Country Status (9)

Country Link
EP (3) EP3888646A1 (cg-RX-API-DMAC7.html)
JP (4) JP6881893B2 (cg-RX-API-DMAC7.html)
KR (3) KR20150103671A (cg-RX-API-DMAC7.html)
CN (4) CN113274378A (cg-RX-API-DMAC7.html)
AU (7) AU2013354979A1 (cg-RX-API-DMAC7.html)
CA (2) CA2894183A1 (cg-RX-API-DMAC7.html)
IN (2) IN2015MU01505A (cg-RX-API-DMAC7.html)
MX (2) MX2015007082A (cg-RX-API-DMAC7.html)
WO (2) WO2014089501A1 (cg-RX-API-DMAC7.html)

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KR101568665B1 (ko) 2015-07-21 2015-11-12 디와이오토 주식회사 모터의 맥동 전류를 증가시키는 브러시 구조
US20190346459A1 (en) * 2016-06-28 2019-11-14 Nestec S.A. Biomarkers of blood-brain barrier dysfunction
JP2018168139A (ja) * 2016-10-21 2018-11-01 マルハニチロ株式会社 ｎ−３系不飽和脂肪酸を含む中性脂肪値の低減または上昇抑制用の組成物、並びに該組成物の製造におけるｎ−３系不飽和脂肪酸の使用
JP7099821B2 (ja) * 2017-12-20 2022-07-12 ポッカサッポロフード＆ビバレッジ株式会社 Ｐｃｓｋ９阻害剤及びコレステロール代謝改善用食品組成物
EP3586640A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586642A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100233280A1 (en) * 2009-03-11 2010-09-16 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
WO2012112531A1 (en) * 2011-02-16 2012-08-23 Pivotal Therapeutics, Inc. Statin and omega 3 fatty acids (epa, dha and dpa) for use in cardiovascular diseases

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GB8819110D0 (en) 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
GB9901809D0 (en) * 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
GB0016045D0 (en) 2000-06-29 2000-08-23 Laxdale Limited Therapeutic combinations of fatty acids
JP2002125618A (ja) * 2000-10-30 2002-05-08 Katsuyuki Wakatsuki 健康食品
EP1714564A1 (en) * 2005-04-21 2006-10-25 N.V. Nutricia Method for treatment and prevention of respiratory insufficiency
WO2007058523A1 (en) 2005-11-17 2007-05-24 N.V. Nutricia Composition with docosapentaenoic acid
JP5658876B2 (ja) * 2006-07-05 2015-01-28 フォトンズ コーポレーション リミテッド 大規模従属栄養培養領域にて産生される超高純度ｅｐａと極性脂質
KR100684642B1 (ko) * 2006-09-14 2007-02-22 주식회사 일신웰스 어유 유래 글리세라이드 유지 조성물 및 이의 제조방법
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WO2012112531A1 (en) * 2011-02-16 2012-08-23 Pivotal Therapeutics, Inc. Statin and omega 3 fatty acids (epa, dha and dpa) for use in cardiovascular diseases

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Publication number Publication date
JP2016501248A (ja) 2016-01-18
AU2020203658A1 (en) 2020-06-25
CN112107570A (zh) 2020-12-22
IN2015MU01505A (cg-RX-API-DMAC7.html) 2016-05-27
MX2015007085A (es) 2016-01-12
AU2013354979A1 (en) 2015-06-11
CN104902888A (zh) 2015-09-09
EP2929041A1 (en) 2015-10-14
KR20150103671A (ko) 2015-09-11
JP2019172697A (ja) 2019-10-10
JP6881893B2 (ja) 2021-06-02
WO2014089511A2 (en) 2014-06-12
AU2013354969A1 (en) 2015-06-11
EP2928462A2 (en) 2015-10-14
AU2017232203A1 (en) 2017-10-12
AU2021201865A1 (en) 2021-04-22
AU2019216634A1 (en) 2019-09-05
KR20150103009A (ko) 2015-09-09
MX2015007082A (es) 2016-01-12
AU2018229440A1 (en) 2018-10-04
EP2928462A4 (en) 2016-06-01
IN2015DE05009A (cg-RX-API-DMAC7.html) 2015-12-18
CA2894366A1 (en) 2014-06-12
EP2929041A4 (en) 2016-06-08
WO2014089501A1 (en) 2014-06-12
KR20210059779A (ko) 2021-05-25
JP2016501249A (ja) 2016-01-18
CA2894183A1 (en) 2014-06-12
CN104937103A (zh) 2015-09-23
WO2014089511A3 (en) 2014-07-31
JP2021120407A (ja) 2021-08-19
EP3888646A1 (en) 2021-10-06

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Application publication date: 20210820