CN113273654A - Compound spina date seed beverage capable of improving sleep and preparation method thereof - Google Patents

Compound spina date seed beverage capable of improving sleep and preparation method thereof Download PDF

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Publication number
CN113273654A
CN113273654A CN202110345812.XA CN202110345812A CN113273654A CN 113273654 A CN113273654 A CN 113273654A CN 202110345812 A CN202110345812 A CN 202110345812A CN 113273654 A CN113273654 A CN 113273654A
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spina date
compound
date seed
improving sleep
carrying
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李欣欣
刘淑芳
张凌
岳艺璇
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Jilin University
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Jilin University
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
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    • A61K36/906Zingiberaceae (Ginger family)
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Abstract

The invention relates to a compound jujube kernel beverage capable of improving sleep and a preparation method thereof, belonging to the field of functional beverages, and the compound jujube kernel beverage is prepared by cleaning and drying spina date seeds, lily, fructus amomi, gardenia and radix ophiopogonis, carrying out superfine grinding, mixing 20-23%, 14-20%, 15-22%, 20-23% and 20-23% of the spina date seeds, fructus amomi, gardenia, radix ophiopogonis and lily in the mixed powder in sequence according to the mass percent of the spina date seeds, the fructus amomi, the gardenia, the radix ophiopogonis and the lily, adding distilled water according to the solid-to-liquid ratio of 1:20-1:40g/mL, carrying out ultrasonic treatment for 20-40min, heating for 1-3 times in a water bath at the temperature of 75-95 ℃, carrying out 40-60min each time, carrying out centrifugation for 20min after filtration, carrying out colloid mill and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization to obtain a finished product. The compound spina date seed beverage has the effects of calming heart, soothing nerves, helping sleep, strengthening spleen and stomach, tonifying qi, promoting the production of body fluid and the like.

Description

Compound spina date seed beverage capable of improving sleep and preparation method thereof
Technical Field
The invention belongs to the technical field of functional beverage production, and particularly relates to a compound spina date seed beverage capable of improving sleep and a preparation method thereof.
Background
With the development of society, the pace of life of people is accelerated and the working pressure is increased, insomnia is the most common problem among young people, and the insomnia is the most common problem among sleep disorders and is mainly expressed as follows: short sleep duration, early awakening, difficulty falling asleep, etc. Nowadays, insomnia has seriously influenced people's study, work and physical and mental health.
At present, the chemicals for treating insomnia at home and abroad mainly comprise barbiturates, melatonin and the like. The medicine can well shorten the time of falling asleep and prolong the sleep time, but the medicine is easy to generate a series of side effects such as drug dependence and the like after being taken, influences the normal secretion of various hormones in the body, disturbs the secretion level of various hormones, causes the imbalance of the endocrine system of the human body and influences the normal development of the human body. How to improve sleep and fight insomnia becomes a popular problem to be solved urgently, finding and researching products with few side effects and small dependence for improving insomnia becomes a research and development hotspot, and with the great development of social economy and the enhancement of health-preserving consciousness of people, functional foods are more and more favored by consumers, people hope to achieve the effect of improving sleep through daily diet, so that the development of a functional product for improving sleep is needed at the present stage to meet the requirements of vast insomnia people.
Disclosure of Invention
The invention aims to provide a compound jujube kernel beverage capable of improving sleep, which has specific traditional Chinese medicine taste, can calm heart, calm nerves, tonify qi and promote the production of body fluid, has a simple preparation method, and reserves flavonoid and saponin active ingredients in the formula as much as possible.
The purpose of the invention is realized by the following technical scheme:
a compound spina date seed beverage capable of improving sleep is prepared by the following steps:
s1, cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis, and Bulbus Lilii, drying until the water content is less than 10%, micronizing, and mixing at a certain ratio to obtain mixed powder;
s2, adding a certain amount of distilled water into the mixed powder, and then carrying out ultrasonic treatment;
s3, heating the liquid after ultrasonic treatment in a water bath;
s4, filtering and centrifuging the liquid after water bath heating;
and S5, performing colloid milling and homogenization treatment on the centrifuged liquid, and filling and sterilizing to obtain the compound spina date seed beverage.
As a more preferable technical scheme of the invention, the particle size of the ultrafine pulverization described in the step S1 is controlled at 200-300 mesh.
As a more preferable technical scheme of the invention, the mixed powder in the step S2 comprises, by mass, 20% -23% of wild jujube seed, 14% -20% of fructus amomi, 15% -22% of fructus gardeniae, 20% -23% of radix ophiopogonis and 20% -23% of lily.
As a more preferable technical scheme of the present invention, the mixed powder described in step S2 sequentially contains, by mass, 21.4% of spina date seed, 14.4% of fructus amomi, 21.4% of fructus gardeniae, 21.4% of radix ophiopogonis and 21.4% of lily.
As a more preferable technical scheme of the invention, the feed-liquid ratio of the mixed powder and the distilled water in the step S2 is 1:20-1:40 g/mL.
As a more preferable technical scheme of the invention, the feed-liquid ratio of the mixed powder and the distilled water in the step S2 is 1:30 g/mL.
As a more preferable technical scheme of the invention, the ultrasonic power in step S2 is 200-300W.
As a more preferable technical solution of the present invention, the ultrasonic power of 250W described in step S2
As a more preferable technical scheme of the invention, the ultrasonic time in the step S2 is 20-40 min.
As a more preferable technical scheme of the invention, the ultrasonic time in the step S2 is 30 min.
As a more preferable technical scheme of the invention, the water bath heating temperature in the step S3 is 75-95 ℃.
As a more preferable technical scheme of the invention, the water bath heating time in the step S3 is 40-60 min.
As a more preferable technical scheme of the invention, the water bath heating times in the step S3 are 1-3.
As a more preferable technical scheme of the invention, the centrifugal rotating speed in the step S4 is 4000r/min, and the centrifugal operation is performed for 20 min.
The beneficial effects are that:
the spina date seed in the formula is dry mature seed of Rhamnaceae plant wild jujube, is sweet in nature and sour in taste, belongs to liver, gallbladder and heart channels, is often used for treating symptoms such as dysphoria, insomnia, palpitation and dreaminess, body deficiency and hyperhidrosis, body fluid deficiency and thirst and the like, has unique efficacy in the field of tranquilization and insomnia, has obvious curative effect, and is called as 'eastern sleeping fruit' by doctors and patients; gardenia is bitter and cold in nature and enters heart, lung and triple energizer channels, and has the effects of purging pathogenic fire, relieving restlessness, clearing heat, promoting diuresis, cooling blood, removing toxic substances, relieving swelling and pain for external use and the like; the lily is sweet and cold in nature, enters heart and lung channels, has the effects of nourishing yin, moistening lung, clearing heart and soothing nerves, and is clinically used for treating dysphoria, palpitation, insomnia, dreaminess and absentmindedness; fructus amomi is warm in nature and pungent in taste and mainly enters spleen, stomach and kidney channels, and is traditionally considered to have the effects of resolving dampness, stimulating appetite, warming spleen, relieving diarrhea, regulating qi and preventing miscarriage; the dwarf lilyturf tuber has sweet and slightly bitter taste and slightly cold nature, enters heart, lung and stomach channels, has the efficacies of nourishing yin, promoting the production of body fluid, moistening lung and clearing heart, and is used for treating symptoms such as vexation, insomnia, lung dryness, dry cough, consumptive disease, cough, body fluid injury, thirst, internal heat, thirst, intestinal dryness, constipation and the like.
The five flavors are combined to prepare the compound beverage, the effects of various components interact with each other, the synergistic effect is realized, the effects of calming the heart and tranquilizing the mind, helping sleep, strengthening the spleen and stomach, tonifying qi and promoting the production of body fluid are realized together, and the compound beverage is used for improving symptoms such as dysphoria, insomnia, palpitation, dreaminess, insomnia, dreaminess, absentmindedness and the like.
The beverage has simple preparation method, and retains flavonoid and saponin active ingredients in the formula as much as possible, wherein the flavonoid and saponin substances are main active ingredients for improving sleep.
The beverage is orange, has uniform and bright color, is clear, has good taste, specific traditional Chinese medicine flavor, lingering aftertaste, slight bitterness, harmonious smell and pure taste, is suitable for the broad masses of people, and has wider market prospect.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments.
All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 21.4%, 14.4%, 21.4% and 21.4% of the spina date seed, the fructus amomi, the gardenia, the radix ophiopogonis and the lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:30g/mL, and carrying out ultrasonic treatment for 30min under the condition that the ultrasonic power is 250W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 50min, wherein the water bath temperature is 90 ℃, and the water bath frequency is 3 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in the embodiment 1 is orange, bright and moderate in color, uniform in color, good in taste, special in traditional Chinese medicine taste, long in aftertaste, slightly bitter, harmonious in smell and pure in taste.
The extraction rate of the total flavonoids as the active ingredients in the beverage prepared in example 1 was found to be 1.07%, and the extraction rate of the total saponins was found to be 14.61%.
Example 2:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 21.4%, 14.4%, 21.4% and 21.4% of the spina date seed, the fructus amomi, the gardenia, the radix ophiopogonis and the lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:30g/mL, and carrying out ultrasonic treatment for 35min under the condition that the ultrasonic power is 250W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 55min, wherein the water bath temperature is 85 ℃, and the water bath frequency is 3 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in the embodiment 2 is orange, bright and moderate in color, uniform in color, good in taste, special in traditional Chinese medicine taste, long in aftertaste, slightly bitter, harmonious in smell and pure in taste.
The extraction rate of the active ingredient total flavonoids in the beverage prepared in example 2 was found to be 0.98%, and the extraction rate of the total saponins was found to be 14.58%.
Example 3:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 23.0%, 15.5%, 23.0% and 23.0% of the spina date seed, the fructus amomi, the gardenia, the radix ophiopogonis and the lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:35g/mL, and carrying out ultrasonic treatment for 30min under the condition that the ultrasonic power is 220W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 50min, wherein the water bath temperature is 85 ℃, and the water bath frequency is 2 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in the embodiment 3 is orange, bright and moderate in color, uniform in color, good in taste, special in traditional Chinese medicine taste, long in aftertaste, slightly bitter, harmonious in smell and pure in taste.
The content of the active ingredient total flavonoids in the beverage prepared in example 2 was found to be 0.92% and the content of the total saponins was found to be 14.37%.
Example 4:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 23.0%, 15.5%, 23.0% and 23.0% of the spina date seed, the fructus amomi, the gardenia, the radix ophiopogonis and the lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:25g/mL, and carrying out ultrasonic treatment for 30min under the condition that the ultrasonic power is 280W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 45min, wherein the water bath temperature is 85 ℃, and the water bath frequency is 3 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in the embodiment 4 is orange, bright and moderate in color, uniform in color, good in taste, special in traditional Chinese medicine taste, long in aftertaste, slightly bitter, harmonious in smell and pure in taste.
The content of the active ingredient total flavonoids in the beverage prepared in example 4 was found to be 0.86% and the content of the total saponins was found to be 14.24%.
Example 5:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 20.0%, 20.0% and 20.0% of the spina date seed, the fructus amomi, the gardenia, the radix ophiopogonis and the lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:25g/mL, and carrying out ultrasonic treatment for 35min under the condition that the ultrasonic power is 280W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 45min, wherein the water bath temperature is 80 ℃, and the water bath frequency is 3 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in the example 5 is orange, bright and moderate in color, uniform in color, good in taste, special in traditional Chinese medicine taste, long-lasting in aftertaste, slightly bitter, harmonious in smell and pure in taste.
The content of the active ingredient total flavonoids in the beverage prepared in example 5 was found to be 0.77%, and the content of the total saponins was found to be 14.17%.
Example 6:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 20.0%, 20.0% and 20.0% of the spina date seed, the fructus amomi, the gardenia, the radix ophiopogonis and the lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:30g/mL, and carrying out ultrasonic treatment for 30min under the condition that the ultrasonic power is 250W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 50min, wherein the water bath temperature is 90 ℃, and the water bath frequency is 3 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in the embodiment 6 is orange, bright and moderate in color, uniform in color, good in taste, special in traditional Chinese medicine taste, long in aftertaste, slightly bitter, harmonious in smell and pure in taste.
The content of the active ingredient total flavonoids in the beverage prepared in example 6 was found to be 1.02%, and the content of the total saponins was found to be 14.39%.
Example 7:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 25.0%, 25.0% and 25.0% of fructus amomi, 25.0% and lily in sequence by mass in the mixed powder to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:30g/mL, and carrying out ultrasonic treatment for 35min under the condition that the ultrasonic power is 220W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 50min, wherein the water bath temperature is 80 ℃, and the water bath frequency is 3 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in the example 7 has bright and moderate color, uniform color, poor taste, specific traditional Chinese medicine flavor, heavy bitter taste, basically harmonious smell and pure taste.
The content of the active ingredient total flavonoids in the beverage prepared in example 7 was found to be 0.60% and the content of the total saponins was found to be 8.97%.
Example 8:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning good-quality spina date seed, fructus amomi, radix ophiopogonis and lily, drying until the water content is lower than 10%, and then carrying out superfine grinding;
(2) mixing 27.3%, 18.1%, 27.3% and 27.3% of the spina date seed, the fructus amomi, the radix ophiopogonis and the lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:25g/mL, and carrying out ultrasonic treatment for 30min under the condition that the ultrasonic power is 280W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 55min, wherein the water bath temperature is 90 ℃, and the water bath frequency is 3 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in example 8 is colorless, has a general taste, a specific traditional Chinese medicine taste, slight bitterness, basically harmonious smell and pure taste.
The content of the active ingredient total flavonoids in the beverage prepared in example 7 was found to be 0.33%, and the content of the total saponins was found to be 11.74%.
The compound beverage of the invention has proper compatibility and complements each other in function, each raw material is an organic whole, and the inventor finds that the composition or the proportion of the raw material components is changed in the research and development process, the whole effect of the compound beverage is obviously reduced, and the analysis may be the result of the content reduction of the active ingredients of total flavone, total saponin and other components.
Example 9:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 16.7 percent, 33.2 percent, 16.7 percent and 16.7 percent of spina date seed, fructus amomi, gardenia, radix ophiopogonis and lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the feed-liquid ratio of 1:35g/mL, and carrying out ultrasonic treatment for 25min under the condition that the ultrasonic power is 280W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 55min, wherein the water bath temperature is 85 ℃, and the water bath frequency is 2 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in example 9 is orange, dark in color, uniform in color, poor in taste, too heavy in flavor of a single substance, heavy in bitter taste, free of peculiar smell and inconsistent in smell.
The content of the active ingredient total flavonoids in the beverage prepared in example 9 was found to be 0.65% and the content of the total saponins was found to be 11.12%.
Example 10:
a preparation method of a compound spina date seed beverage capable of improving sleep comprises the following steps:
(1) cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis and Bulbus Lilii with good quality, drying until the water content is less than 10%, and micronizing;
(2) mixing 16.7 percent, 33.2 percent, 16.7 percent and 16.7 percent of the spina date seed, the fructus amomi, the gardenia, the radix ophiopogonis and the lily in sequence by mass percent to obtain mixed powder, adding distilled water according to the material-liquid ratio of 1:30g/mL, and carrying out ultrasonic treatment for 30min under the condition that the ultrasonic power is 250W;
(3) heating the liquid subjected to ultrasonic treatment in water bath for 50min, wherein the water bath temperature is 90 ℃, and the water bath frequency is 2 times;
(4) filtering and centrifuging the liquid heated in the water bath at the centrifugal speed of 4000r/min for 20 min;
(5) and (4) carrying out colloid milling and homogenization treatment on the centrifuged liquid, and then carrying out filling and sterilization.
The beverage prepared in example 10 is dark orange, has poor taste, heavy single-substance flavor, heavy bitter taste, no peculiar smell and inconsistent smell.
The content of the active ingredient total flavonoids in the beverage prepared in example 10 was found to be 0.69%, and the content of the total saponins was found to be 11.48%.
Animal experiments show that the compound beverage in the embodiments 1-6 of the invention has obviously better sleep improvement effect than the embodiments 7-10, and analysis may be the influence result of the content of total flavonoids and total saponins in the active ingredients.

Claims (10)

1. A compound spina date seed beverage capable of improving sleep is characterized in that: the preparation method comprises the following steps:
s1, cleaning semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis, and Bulbus Lilii, drying until the water content is less than 10%, micronizing, and mixing at a certain ratio to obtain mixed powder;
s2, adding a certain amount of distilled water into the mixed powder, and then carrying out ultrasonic treatment;
s3, heating the liquid after ultrasonic treatment in a water bath;
s4, filtering and centrifuging the liquid after water bath heating;
and S5, performing colloid milling and homogenization treatment on the centrifuged liquid, and filling and sterilizing to obtain the compound spina date seed beverage.
2. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: the mixed powder in the step S1 comprises, by mass, 20% -23%, 14% -20%, 15% -22%, 20% -23% and 20% -23% of spina date seed, fructus amomi, gardenia, radix ophiopogonis and lily.
3. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: the mixed powder in the step S1 contains, by mass, 21.4%, 14.4%, 21.4%, and 21.4% of semen Ziziphi Spinosae, fructus Amomi, fructus Gardeniae, radix Ophiopogonis, and Bulbus Lilii.
4. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: the feed-liquid ratio of the mixed powder and the distilled water in the step S2 is 1:20-1:40 g/mL.
5. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: the feed-liquid ratio of the mixed powder and the distilled water in the step S2 is 1:30 g/mL.
6. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: the ultrasonic power is 200-300W in the step S2.
7. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: the ultrasonic power 250W described in step S2.
8. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: and the ultrasonic time in the step S2 is 20-40 min.
9. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: the water bath heating temperature in the step S3 is 75-95 ℃; heating in water bath for 40-60min in step S3; the water bath heating times in the step S3 are 1-3.
10. The compound spina date seed beverage capable of improving sleep as claimed in claim 1, wherein: and the centrifugal rotating speed in the step S4 is 4000r/min, and the centrifugation is performed for 20 min.
CN202110345812.XA 2021-03-31 2021-03-31 Compound spina date seed beverage capable of improving sleep and preparation method thereof Pending CN113273654A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101816351A (en) * 2010-02-22 2010-09-01 李宏良 Surrogated tea for clearing away heart fire and tranquillizing and preparation method thereof
CN102793165A (en) * 2012-07-20 2012-11-28 惠州市鑫福来实业发展有限公司 Health care deep sleep capsule for improving sleep quality and preparation method thereof
CN104689050A (en) * 2013-12-10 2015-06-10 王新民 Insomnia tea particles
CN105641402A (en) * 2016-02-03 2016-06-08 西安华盛生物制药有限公司 Traditional Chinese medicine composition for improving sleep and preparing method and application thereof
CN106387554A (en) * 2016-09-29 2017-02-15 芜湖市三山区绿色食品产业协会 Manufacturing method of ficus pumila fruit concentrated drink
CN106902241A (en) * 2015-12-23 2017-06-30 郑州国手生物科技有限公司 Strength solves strongly fragrant treatment intractable aypnia particle
CN109463589A (en) * 2018-12-28 2019-03-15 凯瑞欧(天津)生物技术有限公司 A kind of semen ziziphi spinosae formula beverage and preparation method thereof improving sleep quality

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101816351A (en) * 2010-02-22 2010-09-01 李宏良 Surrogated tea for clearing away heart fire and tranquillizing and preparation method thereof
CN102793165A (en) * 2012-07-20 2012-11-28 惠州市鑫福来实业发展有限公司 Health care deep sleep capsule for improving sleep quality and preparation method thereof
CN104689050A (en) * 2013-12-10 2015-06-10 王新民 Insomnia tea particles
CN106902241A (en) * 2015-12-23 2017-06-30 郑州国手生物科技有限公司 Strength solves strongly fragrant treatment intractable aypnia particle
CN105641402A (en) * 2016-02-03 2016-06-08 西安华盛生物制药有限公司 Traditional Chinese medicine composition for improving sleep and preparing method and application thereof
CN106387554A (en) * 2016-09-29 2017-02-15 芜湖市三山区绿色食品产业协会 Manufacturing method of ficus pumila fruit concentrated drink
CN109463589A (en) * 2018-12-28 2019-03-15 凯瑞欧(天津)生物技术有限公司 A kind of semen ziziphi spinosae formula beverage and preparation method thereof improving sleep quality

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
何咏梅,等: "清火栀麦片的稳定性研究", 《中南药学》, vol. 01, no. 01, 20 February 2003 (2003-02-20), pages 28 - 29 *
廖远生,等: "治疗失眠相关中药应用频次研究", 《世界睡眠医学杂志》, vol. 06, no. 04, 30 April 2019 (2019-04-30), pages 1 *
杨小清: "生脉汤加味治疗化疗后失眠30例", 《新中医》, vol. 34, no. 05, 15 May 2002 (2002-05-15), pages 57 - 58 *
阚文博,等: "基于中医传承辅助系统的治疗失眠方剂组方规律分析", 《中国实验方剂学杂志》, vol. 18, no. 12, 20 June 2012 (2012-06-20), pages 1 - 5 *

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