CN1132007C - Medical testing method and sampling apparatus thereof - Google Patents
Medical testing method and sampling apparatus thereof Download PDFInfo
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- CN1132007C CN1132007C CN 00106741 CN00106741A CN1132007C CN 1132007 C CN1132007 C CN 1132007C CN 00106741 CN00106741 CN 00106741 CN 00106741 A CN00106741 A CN 00106741A CN 1132007 C CN1132007 C CN 1132007C
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- sample
- sampling unit
- person under
- under inspection
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Abstract
To provide a method of medical examination enabling samples to be collected and packed safely in a simple operation by the use of simple implements by making it possible to carry the samples in a dried state, and enabling them to be transported by a general means and gathered into a medical examination center for medical examination. In this method of medical examination, implements for medical examination, each provided with a sampling unit including a sample holding sheet and a moisture absorbent, and each including a sample housing sack capable of housing the sampling unit, are given out from a medical examination center to an examinee 32, sampling units with samples held on sample holding sheets are housed in sample housing sacks on the examinee 32 and transported in a dried state to the medical examination center 31, the samples held on the transported sample holding sheets are analyzed for medical examination at the medical examination center 31.
Description
Technical field
The present invention relates to more a kind of individual who is gone to a doctor in particularly be not easy or have any problem hospital or medical inspection centers or live in method and the used sampling device of this method that backwoodsman individual carries out medical test, described method is by from described individuality the sample collection that is used for medical test being focused on a medical test center at a sampling unit and with these samples and with suitable mode it being analyzed.
Background technology
Before a kind of disease was made possible diagnosis, the conventional practice was will be in conjunction with the medical test (being called the person under inspection below) of individuality to be tested always.For a such person under inspection, going to go to a doctor and require to do medical inspection to a hospital or a medical test center is common now.Please one person under inspection's mode of being checked to hospital or medical test center a kind of suitable inspection of disease is missed opportunity, in the urinalysis, the person under inspection in a special container, sends a hospital A urine sample collection device with this urine sample or the medical inspection center is analyzed then under freezing state.
In such medical test practice, the urine sample of Shou Jiing exists with liquid state like this, therefore can not be by any traditional mailing way, for example this hospital or medical test center are sent in post office etc., and should rely on the transportation means of the special use in the limited zone, therefore, utilize the means of transportation of a common distribution can not realize medical inspection in a wider context.
On the other hand, for carrying out a collection of medical test to a collection of individuality to be tested with specialized check purpose efficiently in order to reach one, this will collect these samples to be checked or collect these samples to be tested at the medical test center of the hospital with skilled professional and technical personnel and equipment by the individual.Yet transport liquid sample (for example urine and blood etc.) is inappropriate from the viewpoint of possible accidental danger and damage in batch.At this, each person under inspection need give such medical test center its sample with custom-designed container by special franking means (for example, special postal bag) consignment.
Summary of the invention
The purpose of this invention is to provide a kind of being used for is checked the method for carrying out medical test by analyzing the sample of collecting from the person under inspection to this, in the method by utilizing a sampling device can avoid difficulty in the above-mentioned conventional practice, this sampling device is used for collecting one or several check sample from the person under inspection, then, can it be processed into mailable envelope, need not rely on particular service by common mailing again, the envelope that is processed into is like this returned to the medical test center, this sample is analyzed.
It is at the described sampling device that above-mentioned person to be checked is carried out use in the method for medical test that of the present invention one other purpose provides a kind of, this apparatus makes from person under inspection's health to be collected one or several check sample easily and can become the sample preparation of this collection the deliverable envelope, so that by common delivery mode such envelope is turned back to the medical test center by the post office.
Therefore, the present invention provides following method and the sampling device that is used for this method for medical test.
(1) be used for sample by analyzing the check of collecting from person under inspection's health to the method that this person under inspection carries out medical test, comprise:
Send the person under inspection with a sampling device from the medical science inspection center, described sampling device comprises:
Comprise a sample preserve sheet sampling unit and
Sample bag container, this bag are used to hold described sample unit and have a hygroscopic piece;
By the sample retention sheet of person under inspection's sample collection that handle is used for checking from person under inspection's health at the sampling unit of the described sampling device of receiving;
This sampling unit is encapsulated in this sample bag container so that the dry sample that remains on this sample retention sheet;
This sampling device is returned this medical test center by traditional postal delivery mode;
At this medical test center the sample that is kept on the sample retention sheet in these sampling articles for use of so returning is analyzed.
(2) a kind of method as being limited by above-mentioned (1) is characterized in that described sampling unit has each structure that covers with a protection overlayer of both sides that makes described sample retention sheet.
(3) a kind of by as above-mentioned (1) or (2) defined in method, it is characterized in that described sample bag container comprises that one is located at the ventilative body between described moisture absorption part and the sampling unit and the barrier film of moisture.
(4) a kind of method that is limited by above-mentioned (1), (2) or (3) is characterized in that: described sampling device comprises that a check data is single.
(5) a kind of sampling device, this sampling device is sent a person under inspection from a medical test center, returns this medical test center at sample to be tested after this person under inspection's collection finishes again;
Described apparatus comprises:
Comprise the sample retention sheet that is used to preserve the sample of collecting from the person under inspection and
A sample bag container, this bag are used to hold described sampling unit and have a moisture absorption part.
(6) a kind of sampling device that limits as above-mentioned (5) is characterized in that: each is covered the both sides of described sample retention sheet by a protection overlayer, and described two protect overlayers to constitute a hand holding handle at an end of described sample retention sheet.
(7) a kind of as above-mentioned (5) or (6) sampling device of being limited, but near the mode of the placement that it is characterized in that the moisture absorption part of slabbing should being fixed to this moisture absorption part in the middle of the sample sack according to the film by an air permeable and moisture finished.
Description of drawings
Fig. 1 (a), 1 (b), 1 (c) illustrate an embodiment according to sampling device of the present invention, Fig. 1 (a), and 1 (b), 1 (c) shows sampling unit respectively, the front view of sample bag container and mailing envelope.
Fig. 2 (a), 2 (b), 2 (c) are respectively along Fig. 1 (a), the A-A line of 1 (b) and 1 (c), the cut-open view of B-B line and C-C line.
Fig. 3 (a) shows the actual user mode of sampling unit in the skeleton view mode.
Fig. 3 (b) shows another embodiment of sampling unit in the front view mode.
Fig. 4 shows the sequence of operation of a person under inspection being carried out the method for medical test according to the present invention in the mode of process flow diagram.
Embodiment
With regard to the kind of the disease of utilizing medical testing method of the present invention diagnosis without any restriction, can comprise according to each disease of the analysis result that is kept at the sample on this sample retention sheet being made a diagnostic inference, described sample retention sheet transports under drying regime before this and is received by this medical test center, wherein can enumerate the disease of dysbolism aspect particularly, diabetes for example, the disease of goat and congenital dysbolism aspect, phenylketonuria disease for example, these diseases and the obstacle not only mankind may be suffered from, and animal for example domestic animal and pet also can suffer from.
With regard to regard to the material of sample collection that is used for medical test from the person under inspection without any qualification, every kind of material can be easily collected and the material that can be used for medical inspection can be elected to be target substance into sample from person under inspection one side, they comprise urine, blood, body fluid etc., and wherein urinating with urine is that example is because it is used as the fluid sample collection easily." person under inspection one side " speech is meant to finish and collects from the people of person under inspection's sample operation behavior with this sample and can be regarded as by the medical test center and be examined everyone of people's representative, they comprise and are examined the people, relatives, the nursing staff, the assistant, legal representative, medical science practitioner, nurse and hospital.
Comprise a sample retention sheet according to sampling unit of the present invention, this sample retention sheet is preferably made by a kind of porous and materials such as paper, sponge of slightly oozing out characteristic etc., these materials are as absorbing and preserve, especially for medical test and sample for example urine, blood and body fluid.As a kind of material of not apt to deteriorate especially and impermeability, a kind of analysis purpose filter paper that is used for is suitable.The size of sample retention sheet should be able to be fit to preserve the requirement of the sample of analyzing needed q.s.The shape of sample retention tab should be able to be suitable for being encapsulated in the sample bag container, so that can send the person under inspection with the shape of common quad flat parcel and return from the person under inspection with common mailing way (for example post office or individual mailing system).
The most handy protection overlayer of this sample retention sheet covers on its both sides, and this protection overlayer is provided with for handled easily sample retention sheet when collecting sample with for conveniently this sample being enclosed in sample bag container.For the sample retention sheet, preferably at protection coverlay or the surface layer of a side with a moisture permeable, and opposite side is with not saturating moisture and the protection coverlay of gas or the material of surface layer.The end that the protection overlayer that covers sample retention tab both sides is preferably in them forms a hand operation part or a handle that helps to handle this sample when collecting sample together, thereby can be with bare-handed manipulation sample retention tab, and can not make hand by sample contamination, protection coverlay or surface layer as not saturating moisture can exemplify by polyolefins, for example the laminated film of tygon etc. and polyester and tygon and polyester; Protection as moisture permeable and gas covers fabric thin or that surface layer can preferably exemplify non-woven fabric and be made up of above-mentioned polymkeric substance.
Can satisfy to make the sample on the sample retention tab be in the requirement that under the hold mode sampling unit is contained in the inside according to the structure of sample bag container of the present invention, the structure of this bag container can also satisfy can absorb moisture so that preserve the requirement of sample under drying regime.Preferably can constitute the sample bag container in the following manner: the film of a part of moisture vapor permeable and gas is clipped between this moisture absorption layer and the sampling unit, can be with the film of the film of the similar ventilative body of protection sampling unit or protection coverlay or flaky material or flaky material as barrier film.Sampling unit is contained in the sample bag container, so that make protection overlayer one side and the barrier film in the sample bag container of moisture permeable of sample reception unit opposing.Preferably utilize for example two-sided gluing jointing tape of a kind of seal means etc. that the sample bag container is sealed.As the material of moisture absorption gas, be not react with sample that any composition in the sample is taken place is rotten, but only absorb really or the material of adsorbed moisture.For example a kind of cross-linked resin that is principal ingredient with poly-propionic ester of a kind of polymkeric substance of moisture absorption is preferred for this reason.
Owing to top loading collection in being packaged with is useful on the sample bag container of the sampling unit of the sample retention sheet of the dry sample of check, can send the medical examination center like this, therefore, preferably sample bag container and single an of check data are put into a mode of transporting bag again with a kind of, by tradition mailing form, as the post office, the sample bag container is sent.On check data is single, can write down and comprise person under inspection's name, the suggestion of age and case history and physician etc.Appended check data can adopt the form that is similar to paper slip or card in the check kit utility.
Finish in the following manner according to the method that is used for medical test of the present invention:
At first interior new (freshly prepd) sampling unit, sample bag container and the supporting paper (for example instructions) adorned, and if desired, this medical test apparatus of a check data list is sent to being examined the people from this medical centre, both sending like this can the individual be finished, and also can for example organize hospital or an infirmary to finish by one.
Then, person under inspection one side, collect the sample that is used to check from person under inspection's health by person under inspection or protection people etc.When collecting urine samples, urine is collected in one for example in the dixie cup after, should be immersed in the sample retention tab of sampling unit in the urine of this dixie cup immediately, perhaps the hand holding handle that holds the sample retention sheet by person under inspection two is directly collected urine sample, and the pollution that hand or other gripping means are urinated.
Should be encapsulated in the sample bag container to the sampling unit of sample retention sheet immediately with sample of preserving the new collection that is used for checking, so that preventing this sample for example is subjected to, the pollution of airborne bacterium, mycotic spore, and make sample avoid causing the rotten infringement of sample because of bacterial reproduction.This sampling unit should be contained in so a kind of mode in the sample bag container; Make the protection cover film of moisture permeable of sampling unit relative, seal this bag with above-mentioned closed means immediately then with barrier film in this sample bag container.
In the sample bag container, the moisture that is kept in the sample on the sample retention sheet will be through the protection emulsion sheet of moisture permeable and the barrier film of moisture permeable, is absorbed by hygroscopic agent then and stays dry sample.Under drying regime, can prevent that sample from during transportation taking place any rotten and can prevent to contiguous it foreign material pollution and make dirty.This sampling device can be like this or by it is contained in one transport in the bag by common postal route for example the common method of shipment of mail service send to medical centre.
At this medical test center, from the sampling device that receives, extract sampling unit out, then this sample retention sheet is placed in the extractor, with distilled water immersion so that extract sample, thereby prepare a sample for analysis, though it is transformable being kept at the amount of the sample on the sample retention sheet, but no matter the amount of sample what, can be included in the sample basis by mensuration, for example come sample is carried out chemical analysis for the formation of the constituent in the sample on basis in the detected amount of urine samples such as kreatinin with thick-and-thin ratio.
According to the present invention, be used to diagnose the medical test of a person under inspection's possible disease can finish easily and effectively now, and do not need the person under inspection to come to hospital or medical test center in person, only custom-designed mailable sampling device need not had by the common common mail service of postal route example and send, the sample that wherein is used for checking utilizes a simple device to be easy to collect from person under inspection's health, and the sample of so collecting is kept under drying regime on the special sample retention sheet.
Describe the present invention in detail below in conjunction with accompanying drawing.
In Fig. 1 (a) and Fig. 2 (a); represent sampling unit 1 with numeral 1; a sample retention sheet 2 that is made of filter paper is housed in sampling unit; the side (front side) of this sample retention sheet have one by ventilative body but not the transparent plastic of saturating moisture make the protection cover film, and at its side (rear side) protection cover film 4 of a ventilative body and moisture being arranged and making in addition by the plastic material nonwoven fibrous web.These two coverlays are engaging by heat-sealing on the closing line of bottom and on the closing line 6 at separately two ends and 7 with sample retention sheet 2 respectively.These two coverlays 3 and 4 are in the position except that closing line 5, and loosely is connected on the corresponding side of sample retention sheet 2.This individual again cover film 3 and 4 constitutes a hand holding handle 8 on two ends between its closing line 5 and 6.
Form by a coxopleure 12 and an epimeron 13 at the sample bag container 11 shown in Fig. 1 (b) and 2 (b), the barrier film 15 of the ventilative and moisture that these two sheets and are made by the non-woven fibre complex is surrounding by heat-sealing at the closing line 16 that extends along the bottom of both sides periphery sample bag container under the condition of a sheet 14 of being made by a hygroscopic material and is being bonded together, described hygroscopic material is between epimeron 13 and barrier film 15, so far constitute a bag with the internal interval 17 that is used to hold sampling unit 1, epimeron 13 on top edge and barrier film 15 lumps together by heat sealing, thereby constitutes a closing line 16a.Epimeron 13 folded back at closing line 16a place form a protuberance that is used to seal 18.Coxopleure 12 has one with for example seal element 19 of two-sided gluing jointing tape form in upper perimeter portion, this bonded adhesives covers with an inviscid band of tearing before this in sample is packed bag into, seals to prevent the lug boss that this bag is used to unintentionally seal.
The bag that transports shown in Fig. 1 (c) and 2 (c) is made of the gas impermeable body of a plastic material and the pipe 22 of moisture, the size of this pipe is suitable for sample bag container 11 is enclosed in the inside, and seal into a closing line 24 by an one opening, so that form a bag, and by for remaining opening provides a fastener 25, so that seal and open this opening.
Utilize the medical test of aforesaid sampling device of the present invention to be undertaken by following mode by method of the present invention as described in Figure 4:
At first sampling unit 1 and sample bag container 11 is encapsulated in check data single (not shown, optional) and transports in the bag, will transport bag then and send with the operation instructions of this apparatus and be subjected to procuratorial organ 32.
Be subjected to procuratorial organ 32, from person under inspection's health, collect the sample that is used to check by person under inspection or any other people, when collecting a sample of for example urinating, permission is collected in it for example in the dixie cup, be collected in it on the sample retention sheet 2 immediately then or directly sample collection on sample retention tab 2.In both cases, can carry out sample collection with the handle 8 that naked hand 9 grips sampling unit 1, make the sample retention sheet expose sampling unit 1 with the another hand towards the distolateral relatively closing line 7 that the direction of arrow a indication moves at sample then, can under the situation that can not pollute two hands and equipment, finish sample collection 33 whereby with effective and efficient manner.
The sampling unit 1 that comprises the sample of such collection should be encapsulated in the sample bag container 11 as quickly as possible, because when the infringement that be in the breeding that may be subjected to dropping on top bacterium and fungi exposed state under, often causes sample to go bad.All spill drop but after not making the sampling unit drying removing; with following manner this sample is enclosed holding in the gap 17 of sampling unit in the bag: between the overlapping lug boss 18 that folds back and seal, make breathable protect cover film 4 opposing with barrier film 15 in sample bag container 11.Tear the peelable band (not going out) on the two-sided gluing jointing tape that covers seal 19 then,, seal this bag by the protuberance 18 that is used to seal being pressed in the gluing jointing tape of seal 19.
In this case, the moisture that is kept in the sample on the sample retention sheet 2 will flow into hygroscopic materials through moisture permeable diaphragm 15.Under drying regime, the infringement that the constituent of sample is neither gone bad is not polluted yet and is adjacent near material.Like this, transport in the bag 21, transport bag 21 with fastener 25 sealing then, finish packing 34 by sample bag container 11 is packaged in, preparation by common mailing way for example the common mail service mode of post office transport.
At medical test center 31, take out sample unit 1 bag 21 from transporting of sending of person under inspection one side who receives, utilize the sample in this sampling unit 1 of distilled water diluting, from this sample retention sheet, extract sample, to prepare an analytic sample that is used for medical test.Though being kept at the amount of the sample on the sample retention sheet 2 can change, but no matter the amount of sample what, can by mensuration be included in the sample with all the time not the basis of control with changed scale for example the constituent that is measured as in the sample on basis of the kreatinin in the urine sample tested come sample is carried out chemical analysis.
This sampling device sent to person under inspection one side or return and directly to finish or, for example finish in person under inspection one side's 32 hospital or clinic indirectly by a tissue by the person under inspection from person under inspection one side.In each case, can grip sampling unit 1 with a naked hand and soak sample retention tab 2 with sample simply and finish sample collection, not cause the pollution of hand simultaneously and do not need complicated step, for example to the drying of the sample of collection.Simultaneously by being included in the hygroscopic material in the sample bag container 11 and passing through encapsulation simply and preserve the sampling unit 1 of collecting sample, the dry sample of collecting that is somebody's turn to do.By utilizing sampling device of the present invention, make and going bad and other material of making dirty of sample will can not taken place between the delivery period at sampling device.
Therefore by in any method of shipment easily ordinary post mode in the mail service for example, sampling device of the present invention is sent to a large amount of persons under inspection and return from these persons under inspection, can accurately carry out check in batch.Thereby can carry out medical test to the person under inspection effectively and accurately, and since the collection ratio of check sample of the present invention be easier to carry out, think that those people that test to the medical test center in person not too energetically provide sufficient chance.The present invention contributes to disease prevention and cure whereby.
In Fig. 3 (b); show for example alternative embodiment of baby's sampling unit 1 of a person under inspection who is used to use diaper; a sample retention tab 2 is wherein arranged; protective seam 3,4 by the nonwoven fibrous web of moisture permeable and gas is arranged respectively in its both sides; this sampling unit has a joint close 6 along circumferential edges, and this sampling unit 1 also uses by mode similar to the above.
Claims (6)
1. a sample that is used for checking by the confession that analysis is collected from person under inspection's health comprises the method that the person under inspection carries out medical test:
Send the person under inspection with a sampling device from the medical science inspection center, described sampling device comprises:
Comprise a sample preserve sheet sampling unit and
Sample bag container, this bag are used to hold described sampling unit and have hygroscopic piece, and this sample bag container comprises the ventilative body between hygroscopic piece and sampling unit and the barrier film of moisture;
Person under inspection one side, the A urine sample collection device that handle is used for checking from person under inspection's health is at the sample retention sheet of the sampling unit of the described sampling device of receiving;
This sampling unit is encapsulated in this sample bag container so that the urine sample that remains on this sample retention sheet is carried out drying;
This sampling device is returned this medical test center by traditional postal delivery mode; With
At this medical test center the dried urine sample that is kept on the sample retention sheet in this sampling device of so returning is analyzed.
2. the method for claim 1 is characterized in that described sampling unit has each structure that covers with a protection overlayer of both sides that makes described sample retention sheet.
3. claim 1 or 2 method, it is characterized in that: described sampling device comprises that a check data is single.
4. sampling device, this sampling device is sent the person under inspection one side from the medical science inspection center, and collects from this person under inspection at sample to be tested and to return this medical test center after finishing;
Described apparatus comprises:
Comprise the urine sample of collecting from person under inspection's health preserve sample retention sheet thereon sampling unit and
Sample bag container, this bag are used to hold described sampling unit and have hygroscopic piece, and this sample bag container comprises the ventilative body between hygroscopic piece and sampling unit and the barrier film of moisture.
5. the sampling device of claim 4 is characterized in that: each is covered the both sides of described sample retention sheet by a protection overlayer, and described two protection overlayers are at hand holding handle of an end and the common formation of described sample retention sheet of described sample retention sheet.
6. claim 4 or 5 sampling device is characterized in that the placement of the moisture absorption part of slabbing should be finished the mode that this hygroscopic piece be fixed in the middle of the sample bag container according to the film by a ventilative body and moisture.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP03788899A JP3475834B2 (en) | 1999-02-16 | 1999-02-16 | Inspection methods and tools |
| JP37888/1999 | 1999-02-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1266186A CN1266186A (en) | 2000-09-13 |
| CN1132007C true CN1132007C (en) | 2003-12-24 |
Family
ID=12510089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00106741 Expired - Lifetime CN1132007C (en) | 1999-02-16 | 2000-02-16 | Medical testing method and sampling apparatus thereof |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP3475834B2 (en) |
| CN (1) | CN1132007C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108051460A (en) * | 2017-12-07 | 2018-05-18 | 齐鲁工业大学 | A kind of Micro-CT scanning sample preparation methods of stationery substance |
| CN110646274B (en) * | 2019-09-18 | 2022-04-22 | 山东省立医院 | Disposable intraoperative frozen pathological tissue sampling and collecting device and application thereof |
-
1999
- 1999-02-16 JP JP03788899A patent/JP3475834B2/en not_active Expired - Lifetime
-
2000
- 2000-02-16 CN CN 00106741 patent/CN1132007C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000235027A (en) | 2000-08-29 |
| CN1266186A (en) | 2000-09-13 |
| JP3475834B2 (en) | 2003-12-10 |
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