CN113144044A - Anti-infection skin and bone regeneration medicine composition for injury - Google Patents

Anti-infection skin and bone regeneration medicine composition for injury Download PDF

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Publication number
CN113144044A
CN113144044A CN202110432934.2A CN202110432934A CN113144044A CN 113144044 A CN113144044 A CN 113144044A CN 202110432934 A CN202110432934 A CN 202110432934A CN 113144044 A CN113144044 A CN 113144044A
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parts
solvent
skin
myrrh
bone regeneration
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CN202110432934.2A
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Chinese (zh)
Inventor
张国升
巩振尧
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • A61K36/126Drynaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835Aquilaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics

Abstract

The invention discloses an anti-infection skin and bone regeneration medicine composition for injury, which consists of the following components in parts by mass: musk: 1-2 parts; sea horse: 5-8 parts; gardenia jasminoides ellis: 20-25 parts; elephant skin: 10-15 parts; snow cleaning: 20-25 parts; myrrh: 15-20 parts of a solvent; myrrh: 15-20 parts of a solvent; frankincense: 15-20 parts of a solvent; rhizoma drynariae: 15-20 parts of a solvent; pangolin scales: 10-15 parts; agilawood: 10-15 parts; reducing the fragrance of true rice: 10-15 parts. The invention adopts a simple plaster mode to treat the injury of the affected part, adopts the medicines which can not treat the skin trauma at all, treats deep sclerotin at the same time, has good adaptability of the two medicines, does not generate conflict, and is beneficial to the organism repair of patients.

Description

Anti-infection skin and bone regeneration medicine composition for injury
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, in particular to an anti-infection skin and bone regeneration medicine composition for injuries.
Background
In our lives, fall injuries are often encountered, the types of injuries are complicated, some injuries are skin injuries, some injuries are bone injuries, and even some injuries are skin and bone injuries, and although the injuries are not difficult to treat, the injuries, particularly injuries involving internal bone injuries, are difficult to observe visually, particularly when the injuries are small or the severity of the disease of a patient is not well understood, the injuries of the bone are overlooked, and only the injuries of the skin visible to the external naked eye are treated, so that the recovery of the patient is not facilitated.
Disclosure of Invention
The present invention aims at providing one kind of anti-infective composite medicine for treating wound and regenerating skin and bone.
In order to achieve the purpose, the invention provides the following technical scheme: an anti-infection skin and bone regeneration medicine composition for injury comprises the following components in parts by weight:
musk: 1-2 parts; sea horse: 5-8 parts; gardenia jasminoides ellis: 20-25 parts; elephant skin: 10-15 parts; snow cleaning: 20-25 parts; myrrh: 15-20 parts of a solvent; myrrh: 15-20 parts of a solvent; frankincense: 15-20 parts of a solvent; rhizoma drynariae: 15-20 parts of a solvent; pangolin scales: 10-15 parts; agilawood: 10-15 parts; reducing the fragrance of true rice: 10-15 parts.
Preferably, the components in the optimal mass parts are musk: 15 g; sea horse: 12, the number of the channels is 12; gardenia jasminoides ellis: 350 g; elephant skin: 150 g; snow cleaning: 350 g; myrrh: 300 g; frankincense: 300 g; rhizoma drynariae: 250 g; pangolin scales: 250 g: agilawood: 175 g; reducing the fragrance of true rice: 175 g.
Preferably, the preparation steps of the composition are as follows:
firstly, preparing the high-quality traditional Chinese medicinal materials, cleaning and airing for later use;
secondly, crushing and smashing the traditional Chinese medicine materials by a crusher respectively, and smashing to 100 meshes for later use;
thirdly, uniformly stirring the crushed medicine powder in proportion to obtain a mixture of the combined medicines;
fourthly, using a clean heatable container, adding vaseline and medical paraffin into the container, heating until the solid is melted into liquid, keeping the temperature at 80-90 ℃, then continuously adding the mixture of the combined medicaments into the container, and continuously stirring in the adding process to continuously dissolve the mixture;
fifthly, after the addition is finished, continuing to heat for more than 30 minutes, and taking out and cooling; the decocted pasty medicine is uniformly spread on gauze, then is applied on the position to be treated and is fixed by adhesive plaster, and the application method is to apply the plaster for 1 to 2 times per day.
The pharmacological and medicinal properties of the components of the invention are as follows:
musk: pungent taste and warm nature; it has effects of inducing resuscitation, refreshing mind, promoting blood circulation, dredging channels, relieving swelling and pain. Mainly treats amenorrhea syndromes of coma, sore and ulcer pyogenic infections, scrofula and subcutaneous nodule, swollen sore throat, blood stasis amenorrhea, abdominal mass, heart and abdomen pain, headache, traumatic injury, wind-cold-dampness arthralgia, dystocia, dead fetus and retained afterbirth;
sea horse: sweet in flavor and warm in nature, and is mainly used for warming kidney, tonifying yang, dissipating stagnation and relieving swelling. Can be used for treating sexual impotence, enuresis, asthma due to kidney deficiency, abdominal mass accumulation, and traumatic injury; treating carbuncle and furuncle;
gardenia jasminoides ellis: bitter taste and cold nature, and has effects of clearing heat, purging pathogenic fire, cooling blood and stopping bleeding;
elephant skin: sweet and salty taste, warm nature, hemostasis and protection to wound surface;
snow cleaning: the product has mild nature and slightly salty taste, enters heart and liver meridians when imported, and has the effects of removing blood stasis and stopping bleeding;
myrrh: bitter in property, pungent and neutral in property, and entering heart, liver and spleen channels, the efficacy is mainly to activate blood, alleviate pain, detumescence and promote granulation;
frankincense: the medicine can enter heart and liver channels of a human body, has slightly bitter taste, can play roles of dredging and discharging blood, promoting blood circulation to diminish inflammation, dissipating blood stasis to relieve pain, removing necrotic tissue and promoting tissue regeneration, and also belongs to a medicine commonly used in traumatology;
rhizoma drynariae: can mainly treat soreness and weakness of waist and knees, flaccidity and weakness of bones and myasthenia of limbs, has obvious effects of tonifying kidney and strengthening bones, healing wounds and reuniting tendons and relieving pain;
pangolin scales: has the effects of promoting blood circulation, eliminating symptoms, dredging channels, promoting lactation, relieving swelling, expelling pus, dispelling pathogenic wind, and dredging collaterals. Can be used for treating amenorrhea, obstruction of breast milk, carbuncle, swelling, sore, rheumatalgia, apoplexy, paralysis, numbness, and spasm;
agilawood: mild in nature and pungent and bitter in flavor, and has the effects of activating qi-flowing, relieving pain, warming middle-jiao, relieving vomiting, absorbing qi and relieving asthma, and entering spleen, kidney and stomach channels;
reducing the fragrance of true rice: odor: pungent, warm and non-toxic, it is indicated for knife wound bleeding, abscess and malignant toxicity.
Compared with the prior art, the invention has the beneficial effects that: the anti-infection skin and bone regeneration medicine composition for injury adopts a simple plaster mode to treat the injury of an affected part, adopts medicines which can not treat skin trauma to the utmost extent, treats deep bone at the same time, has good adaptability of the two medicines, does not generate conflict, and is beneficial to the organism repair of a patient.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the case of the example 1, the following examples are given,
step one, preparing musk: 25 g; sea horse: 10, the number of the channels is 10; gardenia jasminoides ellis: 350 g; elephant skin: 150 g; snow cleaning: 350 g; myrrh: 300 g; frankincense: 300 g; rhizoma drynariae: 250 g; pangolin scales: 250 g: agilawood: 175 g; reducing the fragrance of true rice: 175 g. Cleaning and airing for later use;
secondly, crushing and smashing the traditional Chinese medicine materials by a crusher respectively, and smashing to 200 meshes for later use;
thirdly, uniformly stirring the crushed medicine powder in proportion to obtain a mixture of the combined medicines;
fourthly, using a clean heatable container, adding vaseline and medical paraffin into the container, heating until the solid is melted into liquid, keeping the temperature at 80-90 ℃, then continuously adding the mixture of the combined medicaments into the container, and continuously stirring in the adding process to continuously dissolve the mixture;
fifthly, after the addition is finished, continuing to heat for 30 minutes, and taking out and cooling; the decocted pasty medicine is uniformly spread on gauze, then is applied on the position to be treated and is fixed by adhesive plaster, and the application method is to apply the plaster for 1 to 2 times per day.
In the case of the example 1, the following examples are given,
step one, preparing musk: 15 g; sea horse: 12, the number of the channels is 12; gardenia jasminoides ellis: 350 g; elephant skin: 150 g; snow cleaning: 350 g; myrrh: 300 g; frankincense: 300 g; rhizoma drynariae: 250 g; pangolin scales: 250 g: agilawood: 175 g; reducing the fragrance of true rice: 175 g. Cleaning and airing for later use;
secondly, crushing and smashing the traditional Chinese medicine materials by adopting a crusher respectively, and smashing to 100-mesh and 200-mesh for later use;
thirdly, uniformly stirring the crushed medicine powder in proportion to obtain a mixture of the combined medicines;
fourthly, using a clean heatable container, adding vaseline and medical paraffin into the container, heating until the solid is melted into liquid, keeping the temperature at 80-90 ℃, then continuously adding the mixture of the combined medicaments into the container, and continuously stirring in the adding process to continuously dissolve the mixture;
fifthly, after the addition is finished, continuing heating for 50 minutes, and taking out and cooling; the decocted pasty medicine is uniformly spread on gauze, then is applied on the position to be treated and is fixed by adhesive plaster, and the application method is to apply the plaster for 1 to 2 times per day.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (3)

1. An anti-infective skin and bone regeneration composition for a lesion, comprising: the composition comprises the following components in parts by mass:
musk: 1-2 parts; sea horse: 5-8 parts; gardenia jasminoides ellis: 20-25 parts; elephant skin: 10-15 parts; snow cleaning: 20-25 parts; myrrh: 15-20 parts of a solvent; myrrh: 15-20 parts of a solvent; frankincense: 15-20 parts of a solvent; rhizoma drynariae: 15-20 parts of a solvent; pangolin scales: 10-15 parts; agilawood: 10-15 parts; reducing the fragrance of true rice: 10-15 parts.
2. The anti-infective skin and bone regeneration pharmaceutical composition for wounds according to claim 1, wherein the pharmaceutical composition comprises: the best mass parts of the components are musk: 15 g; sea horse: 12, the number of the channels is 12; gardenia jasminoides ellis: 350 g; elephant skin: 150 g; snow cleaning: 350 g; myrrh: 300 g; frankincense: 300 g; rhizoma drynariae: 250 g; pangolin scales: 250 g: agilawood: 175 g; reducing the fragrance of true rice: 175 g.
3. The anti-infective skin and bone regeneration pharmaceutical composition for wounds according to claim 1, wherein the pharmaceutical composition comprises: the preparation steps of the composition are as follows:
firstly, preparing the high-quality traditional Chinese medicinal materials, cleaning and airing for later use;
secondly, crushing and smashing the traditional Chinese medicine materials by adopting a crusher respectively, and smashing to 100-mesh and 200-mesh for later use;
thirdly, uniformly stirring the crushed medicine powder in proportion to obtain a mixture of the combined medicines;
fourthly, using a clean heatable container, adding vaseline and medical paraffin into the container, heating until the solid is melted into liquid, keeping the temperature at 80-90 ℃, then continuously adding the mixture of the combined medicaments into the container, and continuously stirring in the adding process to continuously dissolve the mixture;
fifthly, after the addition is finished, continuing to heat for more than 30 minutes, and taking out and cooling; the decocted pasty medicine is uniformly spread on gauze, then is applied on the position to be treated and is fixed by adhesive plaster, and the application method is to apply the plaster for 1 to 2 times per day.
CN202110432934.2A 2021-04-16 2021-04-16 Anti-infection skin and bone regeneration medicine composition for injury Pending CN113144044A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110432934.2A CN113144044A (en) 2021-04-16 2021-04-16 Anti-infection skin and bone regeneration medicine composition for injury

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110432934.2A CN113144044A (en) 2021-04-16 2021-04-16 Anti-infection skin and bone regeneration medicine composition for injury

Publications (1)

Publication Number Publication Date
CN113144044A true CN113144044A (en) 2021-07-23

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703652A (en) * 2009-11-26 2010-05-12 周小萍 Mastic rheumatism aerosol and preparation method thereof
CN104721254A (en) * 2015-03-27 2015-06-24 姜启禹 Skin healing and tissue regeneration cream
CN106563049A (en) * 2015-10-10 2017-04-19 山东省文登市整骨科技开发有限公司 Plaster

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703652A (en) * 2009-11-26 2010-05-12 周小萍 Mastic rheumatism aerosol and preparation method thereof
CN104721254A (en) * 2015-03-27 2015-06-24 姜启禹 Skin healing and tissue regeneration cream
CN106563049A (en) * 2015-10-10 2017-04-19 山东省文登市整骨科技开发有限公司 Plaster

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
李中心: "散瘀镇痛酊的制备", 《中成药》 *
钱永昌,等: "生肌像皮膏的研制", 《中国中医药科技》 *
阎贵旺,徐林茂: "祛腐托里生肌法治疗外科感染性疾病", 《中国临床医生》 *

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