CN113116751B - Composition of resident type facial mask - Google Patents
Composition of resident type facial mask Download PDFInfo
- Publication number
- CN113116751B CN113116751B CN201911413588.2A CN201911413588A CN113116751B CN 113116751 B CN113116751 B CN 113116751B CN 201911413588 A CN201911413588 A CN 201911413588A CN 113116751 B CN113116751 B CN 113116751B
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Birds (AREA)
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- Microbiology (AREA)
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- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to a composition of a resident facial mask, which comprises a film forming agent (A), a moisturizing penetrating agent (B), a rheology modifier (C), a wetting agent (D) and water (E), wherein the film forming agent (A) comprises polyurethane-35 (A-1). The mask formed by the method provides a transparent appearance by controlling the usage amount of the film forming agent (A) and the weight ratio of the film forming agent (A) to the moisturizing penetrating agent (B), and after a period of use, the mask still keeps good comfort, skin adhesion, stripping easiness and moisturizing effect, and can effectively isolate color cosmetics and anti-adhesion pollutants.
Description
Technical Field
The present invention relates to a composition for a facial mask, and more particularly, to a composition for a leave-on facial mask which is transparent, easily removable, does not tighten, and effectively isolates color cosmetics and resists the attachment of contaminants.
Background
Recently, people pay attention to health and beauty of the face, wherein the facial mask has the effects of moisturizing, whitening, cleaning and the like, and is a popular and commonly used facial product. Currently, the commercial masks include cleansing masks, patch masks, and peel masks, wherein the peel mask generally comprises polyvinyl alcohol (polyvinyl alcohol, PVA)/polyvinylpyrrolidone (PVP).
Although the various masks described above have many advantages, they have disadvantages. For example, cleansing masks do not form a thin and uniform elastic film on the skin, but do not isolate make-up and resist adhering contaminants. Furthermore, the patch type mask does not have a transparent appearance, and can not be used for making up on the mask, and can not be used for isolating make-up and resisting attachment of pollutants. In addition, the PVA/PVP peel-off mask has a transparent appearance, but the mask is not breathable and taut, is not suitable for long-term use, is susceptible to damage to the keratinous tissue upon peeling, and is not resistant to the attachment of contaminants.
In view of the foregoing, there is a need to develop a composition for a resident facial mask to improve the above-mentioned disadvantages of the conventional facial mask.
Disclosure of Invention
Therefore, one aspect of the present invention is to provide a composition for a resident facial mask, which can provide a transparent appearance by controlling the usage amount of the film forming agent (a) and the weight ratio of the film forming agent (a) to the moisturizing penetrating agent (B) of the composition, and can maintain good comfort, skin adhesion, stripping easiness and moisturizing effect after a predetermined period of use, and can effectively isolate color cosmetics and prevent adhering pollutants. In addition, the transdermal permeability of the active additive (G) is enhanced by the moisturizing osmotic agent (B) to enhance the efficacy of the active additive (G).
According to one aspect of the present invention, a composition for a resident facial mask is provided. The composition of the resident facial mask comprises a film forming agent (A), a moisturizing penetrating agent (B), a rheology modifier (C), a wetting agent (D) and water (E), wherein the film forming agent (A) comprises polyurethane-35 (A-1). The film former (a) is used in an amount of more than 8 to less than 22 weight percent and the weight ratio of the film former (a) to the moisturizing penetrant (B) is 2.4 to 12, based on 100 weight percent of the total composition.
According to an embodiment of the present invention, the film former (a) is used in an amount of 10 to 20 wt% based on 100 wt% of the total composition.
According to another embodiment of the present invention, the moisturizing osmotic agent (B) comprises polyoxyethylene polyoxypropylene polyoxybutylglycerol.
According to yet another embodiment of the present invention, the moisture-retaining osmotic agent (B) is used in an amount of 0.5 to 5.5 weight percent based on 100 weight percent of the total composition.
According to a further embodiment of the present invention, the aforementioned rheology modifier (C) comprises at least one of polymers of acrylic acid and/or derivatives thereof.
According to another embodiment of the present invention, the rheology modifier (C) is used in an amount of 0.1 to 2 weight percent based on 100 weight percent of the total composition used.
According to another embodiment of the present invention, the wetting agent (D) is selected from the group consisting of liquid polyols, water-soluble alkoxylated nonionic polymers, and any combination thereof.
According to another embodiment of the present invention, the wetting agent (D) is used in an amount of 5 to 8 weight percent based on 100 weight percent of the total composition used.
According to another embodiment of the present invention, the composition of the resident facial mask optionally comprises a functional additive (F) and/or an active additive (G).
According to another embodiment of the present invention, the functional additive (F) is at least one selected from the group consisting of a pH adjuster (F1), a surfactant (F2), an emollient (F3), an antimicrobial agent (F4) and ethanol (F5), and the active additive (G) is at least one selected from the group consisting of a whitening agent (G1), an antioxidant (G2) and a sensitivity agent (G3).
In summary, the composition of the resident facial mask is coated on the skin to form the resident facial mask, provides transparent appearance, keeps good comfort, skin adhesion, stripping easiness and moisturizing effect after being used for a period of preset time, and can effectively isolate color cosmetics and prevent adhering pollutants.
Drawings
For a more complete understanding of embodiments of the present invention and the advantages thereof, reference is now made to the following descriptions taken in conjunction with the accompanying drawings. It must be emphasized that the various features are not drawn to scale and are for illustration purposes only. The relevant drawings are described as follows:
fig. 1A to 1F are photographs of a face mask composition of an embodiment of the present invention and some comparative examples after 8 hours of application to the face of a subject.
Fig. 2A and 2C are photographs of the stratum corneum of a subject of an embodiment of the invention and a comparative example, respectively, prior to application of the mask composition.
Fig. 2B and 2D are photographs of subjects according to fig. 2A and 2C, respectively, after the subject's stratum corneum has been stripped off to form a mask of one example and a comparative example composition.
Fig. 3A is a photograph of a breathable tape coated lipstick and foundation according to an embodiment of the present invention and a comparative example.
Fig. 3B is a photograph of a tissue immediately adjacent to the breathable tape of fig. 3A.
FIG. 4A is a photograph of a comparative example of pigskin after nano-powder anti-adhesion test.
FIG. 4B is a photograph of pigskin of an embodiment of the present invention and a comparative example after carbon black adhesion resistance test.
FIG. 4C is a photograph of a slide according to an embodiment of the present invention and a comparative example after a sea sand anti-adhesion test.
Fig. 5A is a photograph of a subject's arm skin with color cosmetics, according to an embodiment of the present invention.
Fig. 5B is a photograph of the subject's arm skin according to fig. 5A after removal of make-up.
Fig. 6A is a photograph of subject arm skin treated with dihydroxyacetone solution in accordance with some embodiments of the present invention and some comparative examples.
Fig. 6B is a photograph of the subject's arm skin according to fig. 6A after being coated or uncoated with some of the mask compositions of some of the embodiments of the present invention and some of the comparative examples.
Detailed Description
The application of embodiments of the present invention is discussed in detail below. However, it is to be understood that the embodiments provide many applicable inventive concepts that can be embodied in a wide variety of specific contexts. The particular embodiments discussed are merely illustrative and are not meant to limit the scope of the invention.
The invention provides a composition of a resident type facial mask, which is characterized in that the usage amount of a film forming agent (A) and the weight ratio of the film forming agent (A) to a moisturizing penetrating agent (B) of the composition are controlled, so that the formed facial mask provides a transparent appearance, and after a preset period of use, good comfort, skin adhesion, stripping easiness and moisturizing effect are maintained, and color cosmetics and anti-adhesion pollutants can be effectively isolated. Furthermore, the peeling mask does not cause skin cutin damage due to good peeling easiness, and the mask can be peeled off after a small amount of normal-temperature water is used for wetting the mask, and meanwhile, the color makeup on the mask is removed. In addition, the transdermal permeability of the active additive (G) is enhanced by the moisturizing osmotic agent (B) to enhance the efficacy of the active additive (G).
In other words, the composition of the resident facial mask comprises a film forming agent (A), a moisturizing penetrating agent (B), a rheology modifier (C), a wetting agent (D) and water (E). The film former (A) referred to herein is an aqueous polymer. In some embodiments, film former (A) includes, but is not limited to, polyurethane-35 (Polyurethane-35) (A-1). Polyurethane-35 (A-1) may be commercially available, for example, aqueous polyurethane manufactured by Covesro corporation (Covesro), which is a copolymer synthesized from monomers such as adipic acid (adipic acid), dicyclohexylmethane diisocyanate (dicyclohexylmethane diisocyanate), ethylenediamine (ethylene), hexanediol (hexandiol), neopentyl glycol (neonyl glycol), sodium N- (2-aminoethyl) -3-aminoethane sulfonate (sodium N- (2-aminoethyl) -3-aminoethane sulfonate), and the like.
According to an embodiment of the present invention, the film former (a) is used in an amount of more than 8 to less than 22 weight percent based on 100 weight percent of the total composition. When the film former (a) is used in an amount of 8 weight percent or less, the thus-formed mask is not easy to peel off. When the film former (a) is used in an amount of 22 wt% or more, the resulting mask may be too thick, easily resulting in tight skin and poor comfort. Preferably, the film former (a) is used in an amount of 10 to 20 weight percent. More preferably, the film forming agent (A) is used in an amount of 12 to 15 weight percent, and the facial mask formed thereby provides better comfort, skin adhesion, stripping easiness and moisturizing effect.
In the composition of the resident type mask of the present invention, the moisturizing penetrant (B) referred to herein means a moisturizing agent that helps the active additive (G) penetrate into the skin and enhances the efficacy of the active additive (G) by increasing the solubility of the active additive (G) to the skin. In some embodiments, the moisturizing osmotic agent (B) includes, but is not limited to, polyoxyethylene polyoxypropylene polyoxybutylglycerol. Polyoxyethyl polyoxypropyl polyoxybutyl glycerol is a compound obtained by adding polyoxyethyl, polyoxypropyl, and polyoxybutyl groups to three hydroxyl groups of glycerol. In one embodiment, the polyoxyethylene polyoxypropylene polyoxybutylglycerol may be PEG/PPG/polybutyleneglycol-8/5/3 glycerol (PEG/PPG/polybutylene glycol-8/5/3 glycon) (B).
According to an embodiment of the present invention, the weight ratio of the film former (a) to the moisturizing penetrant (B) may be 2.4 to 12, based on 100 weight percent of the total composition. When the weight ratio of the film forming agent (A) to the moisturizing penetrating agent (B) is less than 2.4, the formed mask cannot be peeled off in a whole piece after being wetted by water, or has a sticky feel. When the weight ratio of the film forming agent (a) to the moisturizing penetrating agent (B) is more than 12, the resulting mask may cause skin to be stretched, causing discomfort to the user. Preferably, the weight ratio of the film former (a) to the moisturizing penetrating agent (B) is 2.4 to 5.
According to an embodiment of the present invention, the film forming agent (a) is used in an amount of more than 8 wt% to less than 22 wt% based on 100 wt% of the total composition, and the weight ratio of the film forming agent to the film forming agent is 2.4 to 12, so that the composition can form a transparent facial mask on the skin, has high elasticity, and can provide high skin adhesion and good air permeability. In addition, after the mask is used for a period of preset time, the formed mask still keeps good comfort, skin adhesion, stripping easiness and moisturizing effect, and can effectively isolate color cosmetics and pollutants.
According to an embodiment of the present invention, the moisture-preserving penetrant (B) may be used in an amount of 0.5 to 5.5 wt%, based on 100 wt% of the total composition. When the moisture-retaining penetrant (B) is used in an amount of 0.5 to 5.5 weight percent, the thus-formed mask has excellent moisture-retaining effect. Preferably, the moisture-retaining penetrant (B) is used in an amount of 1 to 5 wt%, and more preferably 3 wt%.
In the composition of the resident type mask, the rheology modifier (C) is used for adjusting the viscosity of the composition so that the composition can be uniformly coated on the face to form a mask with thin and uniform thickness, thereby providing breathable comfort and good skin attachment degree in use. In some embodiments, the rheology modifier (C) comprises at least one of a polymer of acrylic acid and/or derivatives thereof. The aforementioned acrylic acid derivatives include, but are not limited to, acrylic esters, salts of acrylic esters, alkyl acrylic acids having 10 to 30 carbon atoms, or acrylamides. In some embodiments, the aforementioned polymers may also comprise monomers of vinyl isodecanoate in addition to acrylic acid and/or derivatives thereof. Further, the aforementioned polymer may be a homopolymer or a copolymer, or the aforementioned polymer may be a crosslinked polymer.
In some embodiments, rheology modifier (C) includes, but is not limited to, acrylate copolymer (acrylate copolymer), sodium polyacrylate (sodium polyacrylate), acrylic acid/alkyl acrylic acid crosslinked polymer having 10 to 30 carbon atoms (acrylic acid/C10-30 alkyl acrylate crosspolymer), methyl methacrylate crosslinked polymer (methyl methacrylate crosspolymer), hydroxyethyl acrylate/sodium acryloyldimethyltaurate copolymer (hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer), acrylate/vinyl isodecanoate crosslinked polymer (acrylate/vinyl isodecanoate crosspolymer), acrylic acid/vinyl isodecanoate crosslinked polymer (acrylic acid/vinyl isodecanoate crosspolymer), or acrylamide dimethyltaurate/VP copolymer (ammonium acryloyldimethyl taurate/VP copolymer). In other embodiments, the rheology modifier (C) comprises a combination of at least two of the foregoing polymers.
According to an embodiment of the present invention, the rheology modifier (C) is used in an amount of 0.1 to 2 weight percent based on 100 weight percent of the total composition. When the rheology modifier (C) is used in an amount of 0.1 to 2 weight%, the thickness of the thus formed mask is thin and uniform, and it can provide breathable comfort and good skin-contact. Preferably, the rheology modifier (C) is used in an amount of 0.4 weight percent.
In the composition of the leave-on mask, the humectant (D), herein referred to as humectant (D), refers to a hydrophilic compound that helps to wet the mask when it is desired to strip the mask, so that the mask can be easily stripped in whole. Accordingly, the mask formed by the resident mask composition can be easily stripped without pulling the skin.
In some embodiments, the wetting agent (D) is selected from the group consisting of liquid polyols, water-soluble alkoxylated nonionic polymers, and any combination thereof. The liquid polyol may comprise a polyol having 2 to 8 carbon atoms. For example, the liquid polyol may be ethylene glycol, propylene glycol, butylene glycol, pentylene glycol (pentalene glycol), 1,2-hexanediol (1, 2-hexanediol), octylethylene glycol (capryl glycol), decylene glycol (decylenyl glycol), glycerin, ethylhexyl glycerin (ethylhexyl glycerin), sorbitol, methylbenzyl alcohol (methylbenzyl alcohol), maltitol, etc. The water-soluble alkoxylated nonionic polymer may include, but is not limited to, polyglycerol, dipropylene glycol (dipropylene glycol), ethoxydiglycol (ethoxydiglycol), ethylhexyloxyglycerol (ethylenexydiglycerin), and the like. In other embodiments, the humectant (D) may optionally include, but is not limited to, hyaluronic acid, chitosan, trehalose, and beta-glucan and sugar derivatives, and the like.
According to one embodiment of the present invention, the wetting agent (D) is used in an amount of 5 to 8 weight percent based on 100 weight percent of the total composition. When the amount of the humectant (D) is 5 to 8 weight%, the mask formed therefrom can be peeled off in whole after being wetted with water, to provide convenience in peeling after use. Preferably, the humectant (D) is used in an amount of 5 weight percent.
In the resident facial mask composition of the present invention, the resident facial mask composition may optionally contain a functional additive (F) and/or an active additive (G). The functional additive (F) referred to herein means an additive capable of providing functions such as pH adjustment, emulsification, dispersion, dissolution, skin moisturizing, or antibacterial. In some embodiments, the functional additive (F) is at least one selected from the group consisting of a pH adjuster (F1), a surfactant (F2), an emollient (F3), an antimicrobial agent (F4), and ethanol (F5). The active additive (G) is an additive capable of providing whitening, antioxidation or allergy relief functions. In some embodiments, the active additive (G) is at least one selected from the group consisting of whitening agent (G1), antioxidant (G2) and a sensitivity agent (G3).
The composition of the resident facial mask of the invention can enhance the percutaneous permeability of the active additive (G) through the moisturizing penetrating agent (B) so as to improve the efficacy of the active additive (G).
The composition of the resident facial mask is directly coated on facial skin, and the pH value of the composition can be adjusted by using a pH regulator (F1) to be close to the pH value of the skin so as to avoid skin irritation, wherein the pH value of the composition can be 5 to 8, preferably 6 to 7. The pH adjustor (F1) includes, but is not limited to, small-molecule organic amines, organic weak acids or inorganic alkali salts. Organic amines include, but are not limited to, basic amino acids or lower carbon amine alcohols. For example, the pH adjustor (F1) may be arginine (arginine), 2-amino-2-methyl-1-propanol, 2-amino-2-methyl-1, 3-propanediol, triethanolamine (triethanolamine), citric acid, or the like. Inorganic base salts include, but are not limited to, alkali metal salts. For example, alkali metal salts include, but are not limited to, sodium hydroxide or potassium hydroxide, and the like.
In the resident facial mask composition of the invention, the surfactant (F2) can be used as an emulsifying agent, a cosolvent, a stabilizer and the like. In some embodiments, the surfactant (F2) comprises an anionic surfactant and a nonionic surfactant.
In the present invention, the surfactant (F2) is not particularly limited, and surfactants such as those commonly known to be added to compositions for facial masks may be used. For example, anionic surfactants include, but are not limited to, sodium stearyl glutamate (sodium stearoyl glutamate), potassium cetyl phosphate (potassium cetyl phosphate), phosphate salts, and the like. Specific examples of phosphate salts are lecithins (lecithins), hydroxylated lecithins (hydroxylated lecithin), hydrogenated lecithins (hydrogenated lecithin) and the like, wherein the hydrogenated lecithins are hydrogenated lecithins and have moderate skin adhesion and dispersibility to water, so that the hydrogenated lecithins can increase the ease of stripping by hand of the mask formed from the composition.
For example, nonionic surfactants include, but are not limited to, sorbitan fatty acid esters, sorbitol fatty acid esters, alkyl ethers, and the like. Specific examples of fatty acid esters include ethylhexyl hydrogenated olive oleate (hydrogenated ethylhexyl olivate) and hydrogenated olive oil unsaponifiable matter (hydrogenated olive oil unsaponifiables). Ethylhexyl hydrogenated olive oleate and hydrogenated olive oil unsaponifiables can be used as emulsifiers to aid in the emulsification of oily molecules added to the composition.
Among the functional additives (F), the emollient (F3) is capable of moisturizing the skin, and making the skin tender. Some emollients (F3) may act as moisture blocking agents. When the emollient (F3) forms a protective film outside the stratum corneum of the skin, the protective film can prevent water loss, thereby making the skin tender and transparent.
In the present invention, the emollient (F3) is not particularly limited, and any emollient such as a composition which can be added to a mask as generally known can be used. In some embodiments, the emollient (F3) includes, but is not limited to, fatty acids and esters thereof, cholesterol (cholesterol) and esters or amino acid derivatives thereof, hyaluronic acid and salts thereof, and the like. In some embodiments, the emollient (F3) includes, but is not limited to, natural extracts of animals and/or plants. For example, the emollient (F3) may be caprylic/capric triglyceride (capric/capric triglyceride), jojoba oil, aloe vera extract, sodium hyaluronate, collagen, and the like.
In the functional additive (F), the antibacterial agent (F4) prevents or reduces conditions such as blisters, inflammation, or redness of the skin by killing bacteria that cause blisters and/or inflammation of the skin or inhibiting growth and/or increase in the number of bacteria.
In the present invention, the antibacterial agent (F4) is not particularly limited, and as conventionally known antibacterial agents which can be added to a composition of a mask, can be used. In some embodiments, the antimicrobial agent (F4) includes, but is not limited to, synthetic compounds and/or natural plant extracts.
For example, the aforementioned artificially synthesized compounds may be benzalkonium chloride, triclosan, isopropyl methylphenol (isopropyl methylphenol), benzoyl peroxide, salicylic acid (salicylic acid), 2-bromo-2 nitropropane-1, 3 diol, iodopropynyl butylcarbamate, sodium hydroxymethylglycinate, bisimidazolidinyl urea, triclocarban (triclocarban), parachlorometaxylenol (chloroxylenol), climbazole (climbazole), piroctone olamine (piroctone olamine), zinc pyrithione (zinc pyrithione), sulfur (sulfur), and the like. For example, the natural plant extract may be tea tree essential oil, uganli essential oil, peppermint extract, poplar bark extract (populus tremuloides bark extract), farnesol (farnesol), achillea extract, and the like.
In some embodiments, the antimicrobial agent (F4) includes, but is not limited to, propolis or Leuconostoc/radix Raphani fermentation filtrate (leuconostoc/radish root ferment filtrate), and the like. In other embodiments, a plurality of embodiments of the antibacterial agent (F4) may be mixed and used.
Among the active additives (G), the whitening agent (G1) is used for preventing, inhibiting and/or reducing the formation and/or precipitation of skin melanin and the like, and thereby achieving a whitening effect. The whitening effect referred to herein means that after skin is treated with 30% dihydroxyacetone (dihydroxyacetone) solution for 40 minutes, after waiting for the keratin to be sufficiently brown, the composition of the resident facial mask is coated, stripped after 8 hours, and continuously carried out for 5 days at a frequency of once per day, and then skin melanin content and L value of the skin are measured by using a skin black/red pigment probe and a skin tone probe to obtain individual type angles (individual typological angle, ITA), and the variation rates of melanin content, L value and ITA are calculated, and the evaluated whitening effect is carried out.
In the present invention, the whitening agent (G1) is not particularly limited, and as conventionally known whitening agents which can be added to a composition of a mask, can be used. In some embodiments, the whitening agent (G1) includes, but is not limited to, synthetic compounds and/or natural plant extracts. For example, the whitening agent (G1) may be niacinamide (nicotinamide), tranexamic acid (tranexamic acid), potassium 4-methoxysalicylate (potassium 4-methoxysalicylate), or the like.
Among the active additives (G), the antioxidant (G2) can reduce free radicals, thereby preventing skin from being damaged by the free radicals, to thereby exert an anti-aging effect and keep the skin young.
In the present invention, the antioxidant (G2) is not particularly limited, and any antioxidant which can be added to a composition of a mask as generally known can be used. In some embodiments, antioxidants (G2) include, but are not limited to, synthetic compounds and/or natural plant extracts.
For example, the aforementioned synthetic compounds may be retinol (retinol), butylated hydroxytoluene (dibutyl hydroxy toluene, BHT), butylated hydroxyanisole (butylated hydroxy anisole, BHA), tocopheryl acetate (tocopheryl acetate), propyl gallate, tocopherol, t-butylhydroquinone, ascorbic acid (vitamin C), and dilauryl thiodipropionate, etc. The natural plant extract can be Coicis semen extract, cherry extract, grape seed extract (grapefruit seed extract), etc.
The allergy relieving agent (G3) is used for relieving allergic reactions such as red swelling or stinging caused by skin suffering from irritation. In some embodiments, the sensitivity-soothing agent (G3) includes, but is not limited to, bisabolol and ginger root extracts, oat meal extracts (oat) and mung bean seed extracts (phaseolus radiatus seed extract), and the like.
In addition to the above-described components, in some embodiments, the composition of the resident facial mask of the present invention may optionally include, but is not limited to, preservatives, metal chelating agents, pigments or fragrances, and the like.
For example, but not limiting to the scope of the invention, the preservative may be parabens (paraben), hydroxychloroaniline, phenoxyethanol (phenyloxythanol), benzyl alcohol (benzyl alcohol), benzoic acid (benzoic acid), sodium benzoate (sodium benzoate), imidazolidinyl urea (imidazolidiny urea), 1,3-dimethylol-5,5-dimethylhydantoin (1, 3-dimethylol-5,5-dimethylhydantoin, DMDM hydantoin, formaldehyde (formaldehyde), sorbic acid, chlorobenzeneglycolether (chlorophenasine), methyl chloroisoxazole ketone (methyl chloroisoxazodone), 2-bromo-2-nitro-1, 3-propanediol (2-bromo-2-nitropropane-1, 3-diol), potassium hexadienate (potassium sorbate), hexadienate (62), iodopropynyl formate (iodopropynyl butylcarbamate), and the like. The metal chelator may be ethylenediamine tetraacetic acid (EDTA) or the like. The pigments may be synthetic pigments and/or natural pigments, and all legal cosmetic pigments may be used in the present invention. The perfume may be an artificial perfume and/or a natural perfume. Specific examples of the perfume include rose essence, lavender essence, lily essence, etc.
The film forming agent (A) of the composition is controlled to be used in a range of more than 8 weight percent to less than 22 weight percent, and the weight ratio of the film forming agent (A) to the moisturizing penetrating agent (B) is controlled to be in a range of 2.4 to 12, so that the formed mask has a transparent appearance, and after being used for a preset period, the mask can provide good comfort, skin adhesion, stripping easiness and moisturizing effect, and can effectively isolate color cosmetics and prevent adhering pollutants after being evaluated.
The preset period of the present invention refers to a preset period of time that passes after the composition of the resident facial mask is applied to the face. In some embodiments, the preset period may be 6 hours to 12 hours. Preferably, the predetermined period may be 8 hours.
The following examples are set forth to illustrate the practice of the invention and are not intended to limit the invention thereto, as various modifications and variations may be made by those skilled in the art without departing from the spirit and scope of the invention.
Example 1
In example 1, 0.3 weight percent of acrylic acid (ester)/vinyl isodecanoate crosslinked polymer (C-1), 0.1 weight percent of acrylic acid/alkyl acrylic acid crosslinked polymer (C-2) having 10 to 30 carbon atoms, 5 weight percent of dipropylene glycol (D-1), 0.02 weight percent of citric acid (F1-2) and 70.3 weight percent of water (E) were mixed and stirred to form a uniformly dispersed aqueous phase solution, and 3 weight percent of PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) (trade name: S-753, manufactured by Nitro oil Co., ltd.), 2 weight percent of nicotinamide (G1-1), 2 weight percent of tranexamic acid (G1-2), 1 weight percent of bisabolol and ginger root extract (G3-1 and G3-2), 0.18 weight percent of arginine (F1) and 1 weight percent of hydrogenated olive ethyl hexanoate/hydrogenated olive oil (F-2) were added to the uniformly dispersed aqueous phase solution and stirred and saponified. On the other hand, 5 weight percent of ethanol (F5) and 0.1 weight percent of isopropyl methyl phenol (F4) were mixed and stirred to form a transparent antibacterial solution, and then slowly added to the aqueous phase solution under stirring. After being uniformly mixed, 10 weight percent of polyurethane-35 (A-1) (trade name: C1004, manufactured by Kogyo Co.) was further added, and stirring was continued until homogeneous, to obtain a mask composition of example 1.
Examples 2 to 7 and comparative examples 1 to 5
Examples 2 to 7 and comparative examples 1 to 5 were prepared in the same manner as in example 1. The difference is that the amounts of polyurethane-35 (A-1) used in examples 2 to 4 and comparative examples 1 to 2 are different from those in example 1. The amounts of polyurethane-35 (A-1) and PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) used in examples 5 to 6 and comparative example 4 were different from those in example 1. The amount of polyurethane-35 (A-1) of example 7 used was different from that of example 1, and acrylic acid (ester)/vinyl isodecanoate crosslinked polymer (C-1) and acrylic acid/alkyl acrylic acid crosslinked polymer (C-2) having 10 to 30 carbon atoms were replaced with hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer (C-4). The amount of polyurethane-35 (A-1), the amount of PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) and the amount of dipropylene glycol (D-1) used in comparative example 3 were different from those in example 1. Comparative example 5A polyvinyl alcohol (A-2) and polyvinylpyrrolidone (A-3) were used in place of polyurethane-35 (A-1). The specific conditions for examples 2 to 7 and comparative examples 1 to 5 are shown in table 1.
Example 8
Example 8 was formulated in the same manner as in example 1. Except that the amount of polyurethane-35 (A-1) of example 8 was different from that of example 1, and glycerol (D-2), caprylic/capric triglyceride (F3-1), methyl methacrylate cross-linked polymer (C-3), retinol (G2-1), hydrogenated lecithin (F2-2), cholesterol (F3-2), butylated hydroxytoluene (G2-2), tocopheryl acetate (G2-4), mung bean seed extract (G3-3), butylated hydroxyanisole (G2-3) and oat meal extract (G3-4) were added. The specific conditions for example 8 are shown in table 1.
Examples 9 to 10 and comparative examples 6 to 7
Examples 9 to 10 and comparative examples 6 to 7 were prepared in the same manner as in example 8. Except that the amounts of PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) used in examples 9 to 10 and comparative example 6 were different from those in example 8. The amount of PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) used in comparative example 7 was different from that in example 8. The specific conditions for examples 9 to 10 and comparative examples 6 to 7 are shown in table 1.
Comparative example 8
Comparative example 8 was used by the company MAXiuxiaon, the product name was myo-PHOTO extremely moist, perfect, high moisturizing, multi-effect mask (or , hadalab moisturizing gel mask, https:// jp. Rohto.com/hadalabo/rich-gokujun-perfect-mask /), and was a patch mask.
TABLE 1
1. Comfort feeling
The present invention refers to comfort by applying the mask compositions of examples 1 to 7 and comparative examples 1 to 5 to the face of a subject, wherein 50 subjects each perform a comfort test. After an eight hour period, the subjects were evaluated according to subjective feeling of facial skin, and specific evaluation criteria were as follows, and the results are shown in table 2.
5 points: very comfortable
4 points: high comfort
3 points: ordinary use
2 points: low comfort
1 point: very low comfort
2. Skin-care product
The skin adhesion referred to in the present invention is to apply the mask compositions of examples 1 to 7 and comparative examples 1 to 5 to the face of a subject, wherein 50 subjects each perform the skin adhesion test. After eight hours, the adhesion degree of the mask to the skin was observed and evaluated, and specific evaluation criteria thereof are as follows, and the results are shown in table 2 and fig. 1A to 1F.
5 points: the adhesion degree is very high, and the edge of the mask does not have any turning
4 points: the adhesive degree is high, and the edge of the mask is slightly tilted
3 points: the adhesion degree is common, and the mask part is peeled off
2 points: the adhesion degree is low, and the mask is obviously peeled off
1 point: the adhesion degree is very low, and the mask is completely peeled off
3. Ease of stripping
The ease of peeling referred to in the present invention is a test performed by applying the mask compositions of examples 1 to 7 and comparative examples 1 to 5 to the face of a subject, wherein each of the examples and comparative examples has 50 subjects. After the lapse of eight hours, the mask was peeled off by hand after being wetted with water, and the mask was evaluated in terms of the easiness of peeling off the mask, the integrity of the mask peeling off, and the presence or absence of residue after the mask peeling off, and the specific evaluation criteria are as follows, and the results are shown in table 2.
5 points: when stripping, the mask is not broken, and can be torn off in one piece
4 points: when the mask is stripped, the mask is slightly broken, but can be torn off in one piece
3 points: when stripping, the mask is broken and is required to be torn off for multiple times
2 points: when peeling, the mask is broken and residue of broken chip is generated, and the mask is required to be torn off for multiple times
1 point: when peeling, the mask is broken into pieces and remains on the face, and cannot be torn off in a sheet-like form
4. Moisturizing effect
The moisturizing effect of the invention is tested by 12 subjects, and a double-blind test method is adopted. After the subjects washed their faces with clear water, the skin was acclimatized for 30 minutes in a room with controlled temperature (24 ℃ to 26 ℃) and humidity (50% to 60%), and then the moisture content of the horny layer on both sides of the subject's cheeks was measured using a epidermis moisture meter (Corneometer CM825, courage-Khazaka electronic GmbH, germany) in arbitrary capacitance units (arbitrary capacitance units, a.c.u). Next, the composition of example 2 was applied to the face of a subject to form a mask having a thickness of about 0.2 mm. After eight hours, the mask was peeled off after being wetted with water. After the skin was acclimatized in the aforementioned acclimatization method, the moisture content of the stratum corneum on both sides of the cheek of the subject was measured again. Then, the moisturizing effect was calculated as the percentage of increase (%) in the moisture content of the stratum corneum before the application of the above composition, and the moisturizing effect of the compositions of example 5, example 6, comparative example 3 and comparative example 4 was measured in the same manner, and the results are shown in table 2.
TABLE 2
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Referring to table 2 and fig. 1A to 1F, wherein table 2 is the result of the evaluation test of the comfort, skin adhesion, peeling easiness and moisturizing effect described above, and fig. 1A to 1B, 1C to 1D and 1E to 1F are photographs of the face of the subject after 8 hours of application of the mask compositions of example 2, comparative example 3 and comparative example 5 of the present invention, respectively.
Table 2 shows: the mask formed from the composition of example 2, 12 weight percent polyurethane-35 (a-1), had better stripping easiness than the composition of comparative example 1, 8 weight percent polyurethane-35 (a-1). The mask formed from the composition of example 2, which was 12 weight percent polyurethane-35 (A-1), had a better comfort than the composition of comparative example 2, which was 22 weight percent polyurethane-35 (A-1). The compositions of examples 2, 5 and 6 added with PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) had better comfort, skin adhesion, ease of peeling and moisturizing effects than the compositions of comparative examples 3 and 4 without PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B), with the effect of the 3 weight percent of the composition of example 2 being more effective overall.
5. Degree of damage to the stratum corneum
The degree of the cutin damage referred to in the present invention is that the mask compositions of example 2 and comparative example 5 were applied to the face of a subject, and after eight hours, the mask formed from the mask composition of example 2 was wetted with water, and then peeled off with hands, and the mask formed from the mask composition of comparative example 5 was peeled off with hands. The horny layer on the skin surface before and after the application of the mask composition and the removal of the mask was observed by a microscope, and the evaluation was carried out based on the appearance of the horny layer, and the specific evaluation criteria are as follows, and the results are shown in table 3 and fig. 2A to 2D.
O: the appearance of the horny layer is smooth, and the horny layer is not damaged
And (3) the following steps: rough appearance of the horny layer and damaged horny layer
6. Isolation effect
The insulation effect of the present invention was that the skin having capillary holes was simulated with a breathable tape (manufactured by Minnesota mining Co., ltd., product name: 3M breathable tape, taiwan), the mask composition of example 2 and the mask of comparative example 8 were coated on one side of the breathable tape, and the area where the mask composition was not coated was left as a blank set. After the formation of the mask, the mask composition of example 2 and the mask of comparative example 8 were evaluated for their barrier effect against makeup according to permeation of the lipstick and foundation from the breathable tape to the paper towel after 90 minutes by coating the lipstick and foundation on the tapes of the mask composition and stacking them on the four paper towels on the other side of the tapes, and the specific evaluation criteria are as follows, and the results are shown in table 3 and fig. 3A to 3B.
O: after coating, the lipstick and foundation did not penetrate into the tissues
And (3) the following steps: after coating, the lipstick and the foundation are permeated into the paper towel
7. Adhesion resistance
The adhesion resistance referred to in the present invention was evaluated by coating the mask composition of example 2, the mask of comparative example 8 and the oil-in-water emulsion on pigskin simulating human skin, respectively coating silica nano powder and carbon black on the pigskin, removing non-adherent nano powder by shaking and removing non-adherent carbon black by a blower, and evaluating the adhesion resistance of the mask composition of example 2 and the mask of comparative example 8 to the nano powder and carbon black according to the amounts of the nano powder and carbon black adhering to the pigskin. The aforementioned skin coated with emulsion represents skin coated with emulsion only and is labeled as emulsion group. In addition, the mask formed from the mask composition of example 2 and the mask of comparative example 8 were evaluated for adhesion resistance to sea sand by using a glass slide instead of pigskin and sea sand instead of nano powder, and specific evaluation criteria thereof are as follows, and the results thereof are shown in table 3 and fig. 4A to 4C.
O: the nanometer powder, carbon black or sea sand is not easy to be adhered to the pigskin or the glass slide, and almost no nanometer powder, carbon black or sea sand is adhered to the pigskin or the glass slide
X: the nanometer powder, carbon black or sea sand is easy to be adhered on the pigskin or glass slide, and a large amount of nanometer powder, carbon black or sea sand is adhered on the pigskin or glass slide
8. Ease of removal of make-up
The ease of removal of make-up referred to herein is the application of the mask composition of example 2 to the skin of a subject's arm. After the mask is formed, make-up is performed on the formed mask and the uncoated skin (representing the blank group). After the treatment of removing the makeup, the ease of removal of the makeup was evaluated according to the residual makeup, wherein example 2 used a small amount of normal temperature water sprayed on the mask, after the mask was wetted, the mask was peeled off with hands and the makeup was removed, and the blank group used a large amount of water to wash the makeup. Specific evaluation criteria are shown in table 3 and fig. 5A to 5B.
O: no make-up residue
X: the make-up remains and is hardly removed
TABLE 3 Table 3
Evaluation test | Example 2 | Comparative example 5 | Comparative example 8 | Blank group | Emulsion group |
Degree of Keratin damage | ○ | × | |||
Isolation effect | ○ | × | × | ||
Adhesion resistance of nano powder | ○ | × | × | ||
Adhesion resistance of carbon black | ○ | × | × | ||
Anti-adhesion property of sea sand | ○ | × | × | ||
Ease of removal of make-up | ○ | × |
Referring to table 3 and fig. 2A to 2D, fig. 2A and 2C are photographs of the subject's horny layer before the mask composition is applied, and fig. 2B and 2D are photographs of the subject's horny layer after the mask formed by the mask composition of example 2 and comparative example 5 is peeled off, according to fig. 2A and 2C, respectively. The results show that: the composition of polyurethane-35 (a-1) of example 2 resulted in a mask having a lower degree of stratum corneum damage than the composition of polyvinyl alcohol/polyvinylpyrrolidone of comparative example 5.
Referring to table 3 and fig. 3A to 3B, wherein fig. 3A is a photograph of the breathable tape coated lipstick (upper block) and foundation (lower block) of example 2 and comparative example 8, and fig. 3B is a photograph of the paper towel next to the breathable tape of fig. 3A absorbing the lipstick and foundation penetrated from the breathable tape. The tissue portion of example 2 did not penetrate lipstick and foundation, but the tissue portion of comparative example 8 showed penetration of lipstick and foundation, and the result showed that: the composition of polyurethane-35 (A-1) of example 2 provides a mask having effective makeup-isolating properties as compared to the patch mask of comparative example 8.
Referring to table 3 and fig. 4A to 4C, fig. 4A is a photograph of the pigskin of example 2 and comparative example 8 after the nano powder anti-adhesion test, fig. 4B is a photograph of the pigskin of example 2 and comparative example 8 after the carbon black anti-adhesion test, and fig. 4C is a photograph of the glass slide of example 2 and comparative example 8 after the sea sand anti-adhesion test. In fig. 4A to 4C, the pigskin of example 2 has less nano powder and carbon black attached, and the glass slide of example 2 has less sea sand attached.
The foregoing results show that: compared with the patch type mask of comparative example 8, the mask formed by the resident type mask composition of example 2 has good anti-adhesion effect on nano powder, carbon black and sea sand.
Referring to table 3 and fig. 5A to 5B, fig. 5A is a photograph of the skin of the subject with makeup (left side) and a photograph of the skin of the arm without the mask (right side) of example 2. Fig. 5B is a photograph of the make-up removal treatment according to fig. 5A. Fig. 5A shows that the color cosmetics were applied to the mask formed of the mask composition of example 2 without halation, and the color cosmetics on the mask had the same make-up feel as the color cosmetics on the skin. In addition, the makeup on the mask can be removed while peeling off the mask after wetting the mask with a little water at normal temperature. As described above, since the mask of example 2 has good peeling easiness and can effectively isolate the makeup, the makeup can be easily and completely removed while peeling the mask. The skin without the mask is washed with water, but the makeup cannot be removed by a large amount of water. The foregoing results show that: the mask composition of example 2 formed a mask with good ease of make-up removal.
9. Whitening effect
The whitening effect test was to evaluate the whitening effect of the compositions of examples 8 to 10, comparative examples 6 to 7 with or without coating in 4 subjects. The skin of the arm of the subject was washed with a foam cleanser of 12% sodium laureth sulfate (sodium lauryl ether sulfate, SLES) and then was washed with a foam cleanser having an area of 2cm 2 The skin was left to be rinsed with a 30% dihydroxyacetone solution for 40 minutes and left to stand for 24 hours to fully brown the skin keratin to simulate a tanned skin condition, the appearance of which is shown in fig. 6A. Then, the skin melanin content and L values of the subject's skin were measured with a skin black/red pigment probe (Mexameter MX18, courage-Khazaka electronic GmbH, germany) and a skin tone probe (Colorimeter CL400, courage-Khazaka electronic GmbH, germany), and individual type angles (individual typology angle, ITA) were calculated as skin "pre-treatment" data.
The skin black/red color probe is a probe that obtains the amount of light absorbed by the skin by measuring the amount of light reflected after the skin is irradiated with light of a known amount of light of a specific wavelength, and represents the melanin content in any colorimeter unit (arbitrary mexameter unit).
ITA is a skin color measurement index established based on CIE (international commission on illumination) L x a x b x color space, wherein the higher the ITA, the better the whitening effect, and the ITA can be calculated by the following formula (I): ITA (degree) = { Arc Tangent [ (L-50)/b ] } ×180/pi (I)
L represents darkness and has a value from 0 (black) to 100 (white)
The value b represents the yellow/blue luminosity
Then, the compositions of examples 8 to 10 and comparative examples 6 to 7 were applied to the skin of the subject to form a mask, wherein the application amount of the composition was 120mg, and the mask was peeled off after 8 hours. After continuous 5 days at once daily frequency, the skin melanin content and L value of the skin of the subjects with the coated and uncoated masks were measured, and ITA was calculated as data of "post-treatment" of the skin, and the melanin content, L value and the change rate of ITA were calculated to evaluate the whitening effect of the examples and comparative examples. The results are shown in Table 4, and the appearance of the treated skin is shown in FIG. 6B.
Regarding the melanin content, the L value and the change rate of ITA, the calculation mode is shown as a formula (II):
referring to tables 4, 6A and 6B, wherein table 4 is the result of the aforementioned whitening effect test, and fig. 6A is a photograph of the subject's arm skin after being treated with dihydroxyacetone solution, and fig. 6B is a photograph of the subject's arm skin according to fig. 6A after being coated or uncoated with the compositions of examples 8 to 10 and comparative examples 6 to 7.
TABLE 4 Table 4
From table 4, fig. 6A and fig. 6B, it is shown that: the compositions of examples 8, 9 and 10, to which PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) was added, had a better whitening effect on the skin of the subject's arm than the compositions of comparative examples 6 and 7, to which no PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) was added, wherein the whitening effect was more excellent at the 3 weight percent of the use amount of example 8. This shows that PEG/PPG/polybutyleneglycol-8/5/3 glycerin (B) enhances the whitening effect of tranexamic acid (G1-2) and retinol (G2-1) in the composition of the resident facial mask of the present invention.
In summary, by controlling the usage amount of the film forming agent (a) and the weight ratio of the film forming agent (a) to the moisturizing penetrating agent (B), the resident facial mask composition of the present invention can provide good comfort, skin adhesion, stripping easiness and moisturizing effect after being used for a predetermined period of time, and can effectively isolate color cosmetics and prevent adhering pollutants. Furthermore, the peeling mask does not cause skin cutin damage due to good peeling easiness, and the mask can be peeled and the color makeup on the mask can be removed at the same time after a small amount of normal-temperature water is used for wetting the mask. In addition, the composition of the resident facial mask of the invention can enhance the percutaneous permeability of the active additive (G) through the moisturizing penetrating agent (B), thereby helping to improve the efficacy of the active additive (G).
While the present invention has been described with reference to the embodiments, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention, and it is intended that the invention be limited only by the terms of the appended claims.
Claims (9)
1. A composition for a resident facial mask, the composition comprising:
A film forming agent, wherein the film forming agent is polyurethane-35;
a moisture-retaining penetrating agent, wherein the moisture-retaining penetrating agent is polyoxyethylene polyoxypropylene polyoxybutylglycerol, and the polyoxyethylene polyoxypropylene polyoxybutylglycerol is PEG/PPG/polybutyleneglycol-8/5/3 glycerol;
a rheology modifier;
a wetting agent; and
water, and
wherein a film former is used in an amount of greater than 8 to less than 22 weight percent and the weight ratio of film former to moisturizing penetrant is 2.4 to 12 based on 100 weight percent of the total composition.
2. The composition of claim 1, wherein the film former is used in an amount of 10 to 20 weight percent based on 100 weight percent of the total composition.
3. The composition of claim 1 wherein the moisture-retaining osmotic agent is used in an amount of 0.5 to 5.5 weight percent based on 100 weight percent of the total composition.
4. The composition of claim 1, wherein the rheology modifier comprises at least one of a polymer of acrylic acid and/or derivatives thereof.
5. The composition of claim 1, wherein the rheology modifier is used in an amount of 0.1 to 2 weight percent based on 100 weight percent of the total composition.
6. The composition of claim 1, wherein the wetting agent is selected from the group consisting of liquid polyols, water-soluble alkoxylated nonionic polymers, and any combination thereof.
7. The composition of claim 1, wherein the humectant is used in an amount of 5 to 8 weight percent based on 100 weight percent of the total composition.
8. The composition of claim 1, further comprising a functional additive and/or an active additive.
9. The composition of claim 8, wherein the functional additive is selected from at least one of the group consisting of pH modifiers, surfactants, emollients, antimicrobial agents, and ethanol, and the active additive is selected from at least one of the group consisting of whitening agents, antioxidants, and sensitivity agents.
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Citations (3)
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---|---|---|---|---|
CN106726943A (en) * | 2016-12-19 | 2017-05-31 | 广州睿森生物科技有限公司 | Cosmetic composition, invisible face pack for damaged skin protection and repair and preparation method thereof |
CN107019660A (en) * | 2017-04-27 | 2017-08-08 | 养生堂(上海)化妆品研发有限公司 | Moisture-keeping cosmetics composition |
CN109464303A (en) * | 2018-12-26 | 2019-03-15 | 丹东欣时代生物医药科技有限公司 | Makeup removing facial mask and preparation method thereof |
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CN106726943A (en) * | 2016-12-19 | 2017-05-31 | 广州睿森生物科技有限公司 | Cosmetic composition, invisible face pack for damaged skin protection and repair and preparation method thereof |
CN107019660A (en) * | 2017-04-27 | 2017-08-08 | 养生堂(上海)化妆品研发有限公司 | Moisture-keeping cosmetics composition |
CN109464303A (en) * | 2018-12-26 | 2019-03-15 | 丹东欣时代生物医药科技有限公司 | Makeup removing facial mask and preparation method thereof |
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