CN113100787A - Multi-path crosstalk-free odor stimulator and stimulation method based on odor stimulator - Google Patents

Multi-path crosstalk-free odor stimulator and stimulation method based on odor stimulator Download PDF

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CN113100787A
CN113100787A CN202110544129.9A CN202110544129A CN113100787A CN 113100787 A CN113100787 A CN 113100787A CN 202110544129 A CN202110544129 A CN 202110544129A CN 113100787 A CN113100787 A CN 113100787A
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odor
nasal cavity
pipeline
smell
stimulation
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CN113100787B (en
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孙彪
魏志刚
侯惠让
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Tianjin University
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Tianjin University
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Abstract

The multichannel does not have smell stimulator of crosstalk and because this smell stimulator's amazing method, a left nasal cavity smell pipeline and a right nasal cavity smell pipeline are all connected respectively to N outlet duct of smelling the liquid bottle, the left side intake pipe of respiratory mask is all connected to the gas outlet of each left nasal cavity smell pipeline, the right side intake pipe of respiratory mask is all connected to the gas outlet of each right nasal cavity smell pipeline, each left nasal cavity smell pipeline and each right nasal cavity smell pipeline all are provided with a miniature air pump that is used for controlling air velocity in the pipeline of place and a valve that is used for controlling switching on and closing of the pipeline of place near left side intake pipe or right side intake pipe department, the control end of every miniature air pump and every valve all connects the singlechip that is used for sending control command through the signal line. The invention provides a smell BCI stimulation paradigm for the first time, realizes effective combination of smell stimulation and a brain-computer interface, has safety and reliability, can accurately control the gas flow rate, and avoids tactile discomfort caused by overlarge airflow.

Description

Multi-path crosstalk-free odor stimulator and stimulation method based on odor stimulator
Technical Field
The invention relates to a brain-computer interface system. In particular to a multi-path crosstalk-free odor stimulator and a stimulation method based on the odor stimulator.
Background
As an emerging technology of human-computer interaction, the brain-computer interface (BCI) technology is a popular research direction at home and abroad at present. Currently, the research on BCI mainly focuses on the fields of vision, hearing and motor imagery, including brain-computer interfaces such as steady-state visual evoked potential (SSVEP), event-related potential (ERP) (typical application: P300), event-related synchronous potential (ERS), event-related desynchronized potential (ERD) and the like.
The sense of smell, the oldest and most primitive sense in biological evolution, is closely related to human memory, learning and emotion. BCI based on olfaction is of great advantage. Firstly, compared with the vision and the auditory sense, the stimulation of the olfactory sensation to the brain is more direct and obvious, so that the relative potential of the more obvious event induced by the stimulation of the olfactory sensation is more beneficial to the identification of the relative signal; secondly, olfactory BCI has better safety performance in practical application. For example, in the control of the wheelchair by the disabled, the olfactory stimulation does not influence the disabled to acquire external road information through vision and hearing, so that the control and driving safety of the wheelchair can be improved; in addition, compared with BCI based on motor imagery, olfactory BCI has stronger reliability, because the BCI based on motor imagery is easily affected by external stimuli and has larger individual difference of testees.
The olfactory stimulus paradigm is a very important item in olfactory BCI, and can directly affect the quality of signals (ERP and the like) used for a BCI system, instruction cycles and the like. The stimulation type, the paradigm parameters, the stimulation presentation style, etc. are all important factors for determining the quality of the paradigm. So far, no research on olfactory BCI paradigm is available at home and abroad, and a great number of potential paradigms are yet to be discovered.
Disclosure of Invention
The invention aims to provide a multi-path crosstalk-free odor stimulator capable of accurately controlling the gas flow rate and accurately reflecting the motor imagery of a subject and a stimulation method based on the odor stimulator.
The technical scheme adopted by the invention is as follows: the utility model provides a multichannel does not have smell stimulator of crosstalk, including N smell liquid bottle, every outlet duct of smelling the liquid bottle all connects a left nasal cavity smell pipeline and a right nasal cavity smell pipeline respectively, the left side intake pipe that respiratory mask was all connected to the gas outlet of each left nasal cavity smell pipeline is used for sending into the left nasal cavity of experimenter with the gas that smells the liquid bottle that connects, the right side intake pipe that respiratory mask was all connected to the gas outlet of each right nasal cavity smell pipeline is used for sending into the right nasal cavity of experimenter with the gas that smells the liquid bottle that connects, each left nasal cavity smell pipeline and each right nasal cavity smell pipeline on close on all be provided with a miniature air pump that is used for controlling place pipeline air velocity and a valve that switches on and close that is used for controlling place pipeline, every miniature air pump with every the control end of valve all connect the singlechip that is used for sending control command through the signal line.
A testee wears a respiratory mask in the multi-path crosstalk-free odor stimulator to circularly present odor to the testee, four different odors which represent four different actions are respectively output in one turn, and the four different odors appear randomly; the scalp electroencephalogram signals of the testee with one selected odor are recorded by adopting the portable 14-channel brain electrode cap, and data acquisition of the scalp electroencephalogram signals is carried out by using Cerebus multi-channel neural signal acquisition equipment.
The multi-channel interference-free odor stimulator and the stimulation method based on the odor stimulator firstly provide an olfactory BCI stimulation paradigm, and realize effective combination of olfactory stimulation and brain-computer interfaces. The experimental results verify the superiority, safety and reliability of the model. The stimulator can accurately control the gas flow rate and can avoid the tactile discomfort caused by overlarge gas flow.
Drawings
FIG. 1 is a schematic diagram of the construction of a multi-channel crosstalk-free odor stimulator of the present invention;
FIG. 2 is a flow chart of an embodiment of the present invention for performing N number of stimulation cycles;
fig. 3 is a flow chart of each round of stimulation in an embodiment of the present invention.
In the drawings
1: the singlechip 2: smelling liquid bottle
3: and (4) an air outlet pipe: left nasal cavity smell pipeline
5: right nasal odor line 6: left side air inlet pipe
7: right side intake pipe 8: breathing mask
9: the micro air pump 10: valve gate
11: signal line
Detailed Description
The following describes the multi-channel crosstalk-free odor stimulator and the stimulation method based on the odor stimulator in detail with reference to the embodiments and the drawings.
As shown in fig. 1, the multi-channel no-crosstalk odor stimulator of the present invention comprises N odor bottles 2, wherein the odor bottles 2 of the present invention are provided with more than 2 odor bottles for respectively storing more than 2 different odors of gas. Every smell liquid bottle 2's outlet duct 3 all connects a left nasal cavity smell pipeline 4 and a right nasal cavity smell pipeline 5 respectively, the left side intake pipe 6 that respiratory mask 8 is all connected to each left nasal cavity smell pipeline 4's gas outlet is used for sending into the left nasal cavity of experimenter with the gas that smells in the liquid bottle that connects, the right side intake pipe 7 that respiratory mask 8 is all connected to each right nasal cavity smell pipeline 5's gas outlet is used for sending into the right nasal cavity of experimenter with the gas that smells in the liquid bottle that connects, each left nasal cavity smell pipeline 4 and each right nasal cavity smell pipeline 5 on close on all be provided with a miniature air pump 9 and a valve 10 that is used for controlling switching on and closing of pipeline that are located that are used for controlling the interior air velocity of pipeline that is located in left side intake pipe 6 or right side intake pipe 7 department, miniature air pump 9 can accurate control the air velocity of flow, avoids the velocity of flow to cause too big. The control ends of each micro air pump 9 and each valve 10 are connected with a singlechip 1 for sending control instructions through a signal line 11. Singlechip 1 can adopt 51 singlechips, or Arduino singlechip, or STM32 singlechip.
The stimulation method of the multi-path crosstalk-free odor stimulator is characterized in that a user sits on a chair quietly before an experiment, wears a breathing mask in the multi-path crosstalk-free odor stimulator, and focuses attention. During this process the subject's electroencephalogram signals will produce a responsive transformation according to the target and non-target characteristics of the observed object. Scalp electrical brain signals were recorded by an EEG electrode cap worn by the subject.
As shown in fig. 2, the subjects are cyclically presented with smells, four different smells representing four different actions are respectively output in one turn, and the four different smells appear randomly; as shown in figure 3, in each round of four odor stimulations, the stimulation time of each odor to the testee is fixed to be 300ms, and after one odor stimulation is completed, the rest time of 900ms is fixed to avoid the olfaction fatigue of the testee. After the rest time is over, the next odor stimulation is carried out, and the four different odor stimulations are carried out in sequence.
The stimulation time of four different smells in one round is 4.8s ((300ms +900ms) × 4 smells), the smells noticed by the testee are the target stimulation, and scalp electroencephalogram signals are generated through the portable 14-channel electroencephalogram cap and are collected by Cerebus multi-channel nerve signal collecting equipment. Namely, a portable 14-channel brain electrode cap is adopted to record scalp electroencephalogram signals of one odor selected by a subject, and Cerebus multichannel neural signal acquisition equipment is used for carrying out data acquisition on the scalp electroencephalogram signals. The signal is used for being amplified and filtered by an electroencephalogram amplifier and then input into a computer, and data processing and analysis are further carried out on the electroencephalogram signals. Taking the wheelchair as an example, the four smells correspond to four commands, namely forward, backward, left-turn and right-turn. And outputting a corresponding control instruction according to the identified target stimulation signal to realize effective control of the wheelchair and the like.
In the stimulation method of the multi-channel crosstalk-free odor stimulator, the sampling rate is set to be 1Khz in the electroencephalogram acquisition process, and the sampling holding time of single olfactory stimulation is set to be 300 ms.

Claims (6)

1. The utility model provides a multichannel does not have smell stimulator of crosstalk, a serial communication port, including N smell liquid bottle (2), every is smelled outlet duct (3) of liquid bottle (2) and is all connected a left nasal cavity smell pipeline (4) and a right nasal cavity smell pipeline (5) respectively, the left side intake pipe (6) that respiratory mask (8) are all connected to the gas outlet of each left nasal cavity smell pipeline (4) are used for sending the gas in the smell liquid bottle that connects into the testee left nasal cavity, the right side intake pipe (7) that respiratory mask (8) are all connected to the gas outlet of each right nasal cavity smell pipeline (5) are used for sending the gas in the smell liquid bottle that connects into the testee right nasal cavity, each left nasal cavity smell pipeline (4) and each right nasal cavity smell pipeline (5) on close to left side intake pipe (6) or right side intake pipe (7) department all be provided with a miniature air pump (9) and a miniature air pump (9) that are used for controlling the interior air flow velocity of place pipeline and be used for And the valves (10) are communicated and closed on the pipeline, and the control ends of each micro air pump (9) and each valve (10) are connected with the singlechip (1) for sending a control instruction through a signal line (11).
2. The multi-channel crosstalk-free odor stimulator as claimed in claim 1, wherein more than 2 odor bottles (2) are provided for storing more than 2 different odors of gas respectively.
3. The method for stimulating the multi-channel crosstalk-free odor stimulator according to claim 1, wherein a subject wears a respiratory mask of the multi-channel crosstalk-free odor stimulator to cyclically present the odor to the subject, four different odors representing four different actions are respectively output in one turn, and the four different odors randomly appear; the scalp electroencephalogram signals of the testee with one selected odor are recorded by adopting the portable 14-channel brain electrode cap, and data acquisition of the scalp electroencephalogram signals is carried out by using Cerebus multi-channel neural signal acquisition equipment.
4. The method of claim 3, wherein the stimulation time of each odor to the subject is fixed to 300ms in each round of four odor stimulations, a rest time of 900ms is fixed after one odor stimulation is completed, and after the rest time is completed, the next odor stimulation is performed, and the four different odor stimulations are performed sequentially.
5. The stimulation method according to claim 3, wherein 4.8s is consumed by four different odor stimulations in one round, the odor stimulation noticed by the subject is the target stimulation, and scalp electroencephalogram signals are generated through a portable 14-channel electroencephalogram cap and are collected by Cerebus multichannel neural signal collecting equipment.
6. The stimulation method according to claim 3, characterized in that in the electroencephalogram signal acquisition process, the sampling rate is set to be 1Khz, and the sampling holding time of single olfactory stimulation is 300 ms.
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CN116616720A (en) * 2023-07-21 2023-08-22 心灵秀(苏州)科技有限公司 Smell transmission smell detection equipment and control method thereof

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