CN113081962A - Drops for preventing heart diseases of human and mammals - Google Patents
Drops for preventing heart diseases of human and mammals Download PDFInfo
- Publication number
- CN113081962A CN113081962A CN202110499214.8A CN202110499214A CN113081962A CN 113081962 A CN113081962 A CN 113081962A CN 202110499214 A CN202110499214 A CN 202110499214A CN 113081962 A CN113081962 A CN 113081962A
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- mammals
- heart diseases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a drop for preventing heart diseases of human beings and mammals, which is prepared from the following raw materials in parts by weight: 50-70 parts of food-grade glycerol, 10-20 parts of deionized water and 105-15 parts of micelle nano coenzyme Q; the invention is convenient for taking and absorption; can protect and enhance myocardial activity, enhance blood supply for heart, make heart beat forcefully, prevent aging, improve cardiac hypertrophy, and prevent myocardial infarction.
Description
Technical Field
The invention relates to the technical field of human and animal nutrition, in particular to a drop for preventing heart diseases of human and mammals.
Background
Coenzyme Q10 is a fat-soluble antioxidant, can activate human cells and nutrition of cell energy, and has the functions of improving human immunity, enhancing antioxidation, delaying aging, enhancing human vitality, etc. The coenzyme Q10 can not be well absorbed by human bodies or animals under the conventional state, and the absorption rate can be improved by the micelle nanometer coenzyme Q10, which is 7.5-8 times of the absorption rate. The emulsion drop can be formed by compounding and mixing the glycerin and water, and compared with an injection or a capsule, the emulsion drop is more convenient to take and can be well absorbed.
Disclosure of Invention
The invention aims to provide drops for preventing heart diseases of human beings and mammals, which adopt micelle nano coenzyme Q10 as a raw material, and the prepared drops are convenient to take and absorb and can quickly play a role in protecting the heart.
In order to solve the technical problems, the invention adopts the following technical scheme:
the invention provides a drop for preventing heart diseases of human beings and mammals, which is characterized by being prepared from the following raw materials in parts by weight: 50-70 parts of food-grade glycerol, 10-20 parts of deionized water and 105-15 parts of micelle nano coenzyme Q.
The invention also relates to a preparation method of the drop for preventing the heart diseases of the human beings and the mammals, which comprises the following steps:
1) weighing the raw materials according to the weight;
2) mixing the raw materials in a 45-55 deg.C stirring tank, stirring, shearing to obtain final suspension emulsion, standing at room temperature of 20-25 deg.C, and canning.
The invention has the beneficial effects that: is convenient for administration and absorption; can protect and enhance myocardial activity, enhance blood supply for heart, make heart beat forcefully, prevent aging, improve cardiac hypertrophy, and prevent myocardial infarction.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A drop for preventing heart diseases of human beings and mammals is prepared from the following raw materials by weight: 55g of food-grade glycerol, 18g of deionized water and micelle nano-coenzyme Q1013 g.
The preparation method of the drop for preventing the heart diseases of the human beings and the mammals comprises the following specific steps:
1) weighing the raw materials according to the weight;
2) mixing the raw materials in a 48-degree stirring tank, stirring thoroughly, shearing to obtain final suspension emulsion, standing at room temperature of 24 degrees, and canning.
Example 2
A drop for preventing heart diseases of human beings and mammals is prepared from the following raw materials by weight: 52g of food-grade glycerol, 16g of deionized water and micellar nano-coenzyme Q107 g.
The preparation method of the drop for preventing the heart diseases of the human beings and the mammals comprises the following specific steps:
1) weighing the raw materials according to the weight;
2) mixing the raw materials in a 50-degree stirring tank, stirring thoroughly, shearing to obtain final suspension emulsion, standing at room temperature of 22 deg.C, and canning.
Example 3
A drop for preventing heart diseases of human beings and mammals is prepared from the following raw materials by weight: 65g of food-grade glycerol, 8g of deionized water and micellar nano-coenzyme Q1012 g.
The preparation method of the drop for preventing the heart diseases of the human beings and the mammals comprises the following specific steps:
1) weighing the raw materials according to the weight;
2) mixing the raw materials in a stirring tank with a temperature of 53 ℃, fully stirring, shearing to obtain the final suspension emulsion, standing at the normal temperature of 24 ℃, and canning.
Clinical trials applying the present invention:
90 patients, 45 men and 45 women, age 15-60, 30 patients with heart failure, 30 patients with cardiac hypertrophy and 30 patients with myocardial infarction, wherein 120 cases are divided into 3 groups, and the 3 groups are similar as much as possible to have comparability.
The treatment method comprises the following steps: the medicine is taken twice a day after meals, is dripped into the mouth for 1 ml each time, and is observed after 1 month.
Diagnostic criteria
The method has the following advantages: the clinical symptoms of abdominal pain, abdominal distension, inappetence, nausea, vomiting and the like of the heart failure patient are relieved;
the clinical symptoms of patients with cardiac hypertrophy, such as chest distress, palpitation, dyspnea and the like, are relieved;
the clinical symptoms of the patients with myocardial infarction, such as chest pain, etc., are relieved.
As a result: in example 1, 8 patients with 10 heart failure are effective, and the effective rate is 80%; 9 effective 10 patients with cardiac hypertrophy, the effective rate is 90%; 9 effective patients with 10 myocardial infarction, the effective rate is 90%;
in example 2, 9 patients with 10 heart failure are effective, and the effective rate is 90%; 7 effective 10 patients with cardiac hypertrophy, the effective rate is 70%; 8 effective 10 patients with myocardial infarction, the effective rate is 80%;
in example 3, 10 patients with heart failure have 10 effective patients, and the effective rate is 100%; 9 effective 10 patients with cardiac hypertrophy, the effective rate is 90%; 9 patients with 10 myocardial infarctions have the effect, and the effective rate is 980%.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (1)
1. A drop for preventing heart diseases of human beings and mammals is characterized by being prepared from the following raw materials in parts by weight: 50-70 parts of food-grade glycerol, 10-20 parts of deionized water and 105-15 parts of micelle nano coenzyme Q.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110499214.8A CN113081962A (en) | 2021-05-08 | 2021-05-08 | Drops for preventing heart diseases of human and mammals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110499214.8A CN113081962A (en) | 2021-05-08 | 2021-05-08 | Drops for preventing heart diseases of human and mammals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113081962A true CN113081962A (en) | 2021-07-09 |
Family
ID=76664277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110499214.8A Pending CN113081962A (en) | 2021-05-08 | 2021-05-08 | Drops for preventing heart diseases of human and mammals |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113081962A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264060A (en) * | 2008-04-03 | 2008-09-17 | 东北林业大学 | Super-critical rapid expansion preparation for water-soluble nano cozymase Q10 powder |
| CN104367569A (en) * | 2014-11-06 | 2015-02-25 | 江苏隆力奇生物科技股份有限公司 | Nano coenzyme Q10 oral liquid |
| CN107715108A (en) * | 2017-10-11 | 2018-02-23 | 杜志政 | Treat germanium functional oral liquid of cardiovascular and cerebrovascular disease and preparation method thereof |
-
2021
- 2021-05-08 CN CN202110499214.8A patent/CN113081962A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264060A (en) * | 2008-04-03 | 2008-09-17 | 东北林业大学 | Super-critical rapid expansion preparation for water-soluble nano cozymase Q10 powder |
| CN104367569A (en) * | 2014-11-06 | 2015-02-25 | 江苏隆力奇生物科技股份有限公司 | Nano coenzyme Q10 oral liquid |
| CN107715108A (en) * | 2017-10-11 | 2018-02-23 | 杜志政 | Treat germanium functional oral liquid of cardiovascular and cerebrovascular disease and preparation method thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210709 |