CN113017795B - 活检针设计 - Google Patents
活检针设计 Download PDFInfo
- Publication number
- CN113017795B CN113017795B CN202110250321.7A CN202110250321A CN113017795B CN 113017795 B CN113017795 B CN 113017795B CN 202110250321 A CN202110250321 A CN 202110250321A CN 113017795 B CN113017795 B CN 113017795B
- Authority
- CN
- China
- Prior art keywords
- cannula
- spindle
- spring
- biopsy needle
- needle device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000001574 biopsy Methods 0.000 title claims abstract description 42
- 238000013461 design Methods 0.000 title abstract description 23
- 230000033001 locomotion Effects 0.000 claims abstract description 20
- 230000036316 preload Effects 0.000 claims description 15
- 238000011282 treatment Methods 0.000 claims description 12
- 210000001015 abdomen Anatomy 0.000 claims 4
- 238000013467 fragmentation Methods 0.000 abstract description 3
- 238000006062 fragmentation reaction Methods 0.000 abstract description 3
- 210000001519 tissue Anatomy 0.000 description 95
- 238000012360 testing method Methods 0.000 description 14
- 230000006835 compression Effects 0.000 description 13
- 238000007906 compression Methods 0.000 description 13
- 108010010803 Gelatin Proteins 0.000 description 10
- 229920000159 gelatin Polymers 0.000 description 10
- 239000008273 gelatin Substances 0.000 description 10
- 235000019322 gelatine Nutrition 0.000 description 10
- 235000011852 gelatine desserts Nutrition 0.000 description 10
- 239000011159 matrix material Substances 0.000 description 10
- 238000010304 firing Methods 0.000 description 7
- 230000020347 spindle assembly Effects 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 4
- 229910052751 metal Inorganic materials 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 230000002093 peripheral effect Effects 0.000 description 4
- 230000007423 decrease Effects 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 210000002307 prostate Anatomy 0.000 description 3
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 230000000712 assembly Effects 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 235000008429 bread Nutrition 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 239000013013 elastic material Substances 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000003801 milling Methods 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 238000012935 Averaging Methods 0.000 description 1
- 229910000531 Co alloy Inorganic materials 0.000 description 1
- -1 MP35N Chemical compound 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 229910000990 Ni alloy Inorganic materials 0.000 description 1
- 208000026062 Tissue disease Diseases 0.000 description 1
- WAIPAZQMEIHHTJ-UHFFFAOYSA-N [Cr].[Co] Chemical class [Cr].[Co] WAIPAZQMEIHHTJ-UHFFFAOYSA-N 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 238000013480 data collection Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
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- 239000012858 resilient material Substances 0.000 description 1
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- 238000002560 therapeutic procedure Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
- A61B10/0275—Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B17/3421—Cannulas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B2010/0208—Biopsy devices with actuators, e.g. with triggered spring mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B2010/0225—Instruments for taking cell samples or for biopsy for taking multiple samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B2017/3454—Details of tips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/06—Body-piercing guide needles or the like
- A61M25/065—Guide needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3286—Needle tip design, e.g. for improved penetration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Surgical Instruments (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Prostheses (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110250321.7A CN113017795B (zh) | 2016-05-25 | 2017-05-25 | 活检针设计 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662341292P | 2016-05-25 | 2016-05-25 | |
| US62/341,292 | 2016-05-25 | ||
| CN201780032433.7A CN109152569B (zh) | 2016-05-25 | 2017-05-25 | 活检针设计 |
| CN202110250321.7A CN113017795B (zh) | 2016-05-25 | 2017-05-25 | 活检针设计 |
| PCT/US2017/034505 WO2017205640A1 (en) | 2016-05-25 | 2017-05-25 | Biopsy needle design |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780032433.7A Division CN109152569B (zh) | 2016-05-25 | 2017-05-25 | 活检针设计 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113017795A CN113017795A (zh) | 2021-06-25 |
| CN113017795B true CN113017795B (zh) | 2024-10-18 |
Family
ID=60412622
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110250321.7A Active CN113017795B (zh) | 2016-05-25 | 2017-05-25 | 活检针设计 |
| CN201780032433.7A Active CN109152569B (zh) | 2016-05-25 | 2017-05-25 | 活检针设计 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780032433.7A Active CN109152569B (zh) | 2016-05-25 | 2017-05-25 | 活检针设计 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10188422B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3463101B8 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2019523661A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20190008953A (cg-RX-API-DMAC7.html) |
| CN (2) | CN113017795B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017270207A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112018074199A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3023978C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2963174T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL262903B (cg-RX-API-DMAC7.html) |
| MX (1) | MX2018014299A (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201809873UA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017205640A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10188422B2 (en) * | 2016-05-25 | 2019-01-29 | 3Dbiopsy, Inc. | Biopsy needle design |
| US10952898B2 (en) * | 2018-03-09 | 2021-03-23 | Aquesys, Inc. | Intraocular shunt inserter |
| EP3787520B1 (en) * | 2018-05-04 | 2024-09-25 | Hologic, Inc. | Biopsy needle visualization |
| US12121304B2 (en) | 2018-05-04 | 2024-10-22 | Hologic, Inc. | Introducer and localization wire visualization |
| JP6984922B2 (ja) * | 2018-06-05 | 2021-12-22 | 国立研究開発法人海洋研究開発機構 | バイオプシーデバイス、該バイオプシーデバイスを射出するための射出装置、及び、これらを備えたバイオプシー装置 |
| IT201800006731A1 (it) | 2018-06-27 | 2019-12-27 | Dispositivo di prelievo di campioni di tessuto biologico | |
| US11903569B2 (en) * | 2019-12-31 | 2024-02-20 | URO-1, Inc. | Biopsy system with a core collector that remains radially centered in an outer cannula while severing a tissue sample |
| JP1750112S (ja) * | 2023-03-10 | 2023-08-03 | 穿刺針 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109152569A (zh) * | 2016-05-25 | 2019-01-04 | 3D活体检视股份有限公司 | 活检针设计 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929123A (en) * | 1973-02-07 | 1975-12-30 | Khosrow Jamshidi | Muscle biopsy needle |
| CA1037807A (en) * | 1974-01-09 | 1978-09-05 | Khosrow Jamshidi | Muscle biopsy needle |
| US7063681B1 (en) | 1998-04-23 | 2006-06-20 | Alza Corporation | Trocar for inserting implants |
| US6592530B1 (en) * | 2000-11-20 | 2003-07-15 | Ashkan Farhadi | Automated hot biopsy needle and device |
| US7018343B2 (en) * | 2002-04-05 | 2006-03-28 | Allegiance Corporation | Biopsy needle and biopsy device containing the same |
| US20050159676A1 (en) * | 2003-08-13 | 2005-07-21 | Taylor James D. | Targeted biopsy delivery system |
| US7708751B2 (en) * | 2004-05-21 | 2010-05-04 | Ethicon Endo-Surgery, Inc. | MRI biopsy device |
| WO2006005345A1 (en) * | 2004-07-09 | 2006-01-19 | Sonion Roskilde A/S | Tissue sample flushing system for biopsy device |
| CN100506166C (zh) * | 2004-07-09 | 2009-07-01 | 巴德血管外围设备公司 | 活组织检查装置的输送系统 |
| US7867173B2 (en) * | 2005-08-05 | 2011-01-11 | Devicor Medical Products, Inc. | Biopsy device with replaceable probe and incorporating vibration insertion assist and static vacuum source sample stacking retrieval |
| CN201135459Y (zh) * | 2007-12-21 | 2008-10-22 | 杨进益 | 逼尿肌活检穿刺针 |
| US8197419B2 (en) * | 2008-05-30 | 2012-06-12 | Inrad, Inc. | Biopsy device having specimen length adjustment |
| US8574167B2 (en) * | 2008-12-16 | 2013-11-05 | Devicor Medical Products, Inc. | Needle for biopsy device |
| US20110071432A1 (en) * | 2009-09-24 | 2011-03-24 | Carrillo Jr Oscar R | Fine Needle Aspiration Device with Distal Anchor |
| US8628482B2 (en) * | 2010-02-24 | 2014-01-14 | Devicor Medical Products, Inc. | Needle tip for biopsy device |
| EP2544595B1 (en) * | 2010-03-10 | 2016-01-06 | Boston Scientific Scimed, Inc. | Needle with helical grooves converting axial movement to rotational movement |
| WO2011139876A1 (en) * | 2010-04-29 | 2011-11-10 | Cook Incorporated | Half cannula full core biopsy needle |
| US20120022397A1 (en) * | 2010-07-22 | 2012-01-26 | Jarial Inderjeet S | Needle Set for a Biopsy Device and Related Method |
| CA2808310A1 (en) * | 2010-09-10 | 2012-03-15 | Devicor Medical Products, Inc. | Biopsy device tissue sample holder with removable tray |
| US10448930B2 (en) * | 2011-05-04 | 2019-10-22 | Cook Medical Technologies Llc | Methods and devices for maximizing tissue collection in partial-core biopsy needles |
| DE102011112021B4 (de) * | 2011-08-31 | 2013-10-24 | Hans Haindl | Stanzarme Kanüle |
| US8790361B2 (en) * | 2012-05-23 | 2014-07-29 | Depuy Mitek, Llc | Methods and devices for cutting and removing tissue from a body |
| US9901328B2 (en) * | 2012-06-06 | 2018-02-27 | Carefusion 2200, Inc. | Vacuum assisted biopsy device |
| JP6318233B2 (ja) * | 2013-03-20 | 2018-04-25 | バード・ペリフェラル・バスキュラー・インコーポレーテッド | 生検デバイス |
| DE102013009697A1 (de) | 2013-06-10 | 2014-12-11 | Norbert F. Heske | Biopsiestanznadel |
| EP2862520A1 (en) * | 2013-10-16 | 2015-04-22 | AprioMed AB | Biopsy device |
| WO2015123660A1 (en) * | 2014-02-17 | 2015-08-20 | Vidacare LLC | Powered driver actuated by force on driveshaft and related kits, components, and methods |
| EP3110336B1 (en) | 2014-02-28 | 2018-11-28 | 3DBiopsy, Inc. | Biopsy needle assembly |
| KR102299128B1 (ko) * | 2014-04-28 | 2021-09-08 | 스퍼터링 컴포넌츠 인코포레이티드 | 스퍼터링 장치 |
| US20160030016A1 (en) * | 2014-07-30 | 2016-02-04 | Covidien Lp | Exchangeable core biopsy needle |
| US10245009B2 (en) * | 2014-08-26 | 2019-04-02 | Stephen Henry Miller | Apparatus for safely and accurately excising core tissue samples from palpated nodules or surface lesions |
| WO2016049676A1 (en) | 2014-10-03 | 2016-04-07 | Matthew Sampson | Surgical cutting device and methods of use thereof |
| US20160151054A1 (en) * | 2014-12-02 | 2016-06-02 | Byungesol An | Disposable biopsy devices and methods of obtaining tissue biopsy samples using same |
| CN106068101B (zh) | 2015-02-19 | 2019-05-28 | 奥林巴斯株式会社 | 活检针 |
| US20160361088A1 (en) * | 2015-06-12 | 2016-12-15 | Covidien Lp | Catheter with pre-formed geometry for body lumen access |
| CN205083534U (zh) * | 2015-10-26 | 2016-03-16 | 李斌 | 一种新型活检针 |
-
2017
- 2017-05-25 US US15/605,135 patent/US10188422B2/en active Active
- 2017-05-25 CN CN202110250321.7A patent/CN113017795B/zh active Active
- 2017-05-25 BR BR112018074199-0A patent/BR112018074199A2/pt not_active Application Discontinuation
- 2017-05-25 EP EP17803595.2A patent/EP3463101B8/en active Active
- 2017-05-25 KR KR1020187037113A patent/KR20190008953A/ko not_active Withdrawn
- 2017-05-25 AU AU2017270207A patent/AU2017270207A1/en not_active Abandoned
- 2017-05-25 CA CA3023978A patent/CA3023978C/en active Active
- 2017-05-25 CN CN201780032433.7A patent/CN109152569B/zh active Active
- 2017-05-25 ES ES17803595T patent/ES2963174T3/es active Active
- 2017-05-25 MX MX2018014299A patent/MX2018014299A/es unknown
- 2017-05-25 JP JP2018560607A patent/JP2019523661A/ja active Pending
- 2017-05-25 WO PCT/US2017/034505 patent/WO2017205640A1/en not_active Ceased
- 2017-05-25 SG SG11201809873UA patent/SG11201809873UA/en unknown
-
2018
- 2018-11-08 IL IL262903A patent/IL262903B/en active IP Right Grant
-
2019
- 2019-01-09 US US16/243,538 patent/US10478159B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109152569A (zh) * | 2016-05-25 | 2019-01-04 | 3D活体检视股份有限公司 | 活检针设计 |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2018014299A (es) | 2019-03-14 |
| BR112018074199A2 (pt) | 2019-03-06 |
| US10188422B2 (en) | 2019-01-29 |
| CA3023978C (en) | 2020-09-01 |
| EP3463101B1 (en) | 2023-09-13 |
| EP3463101A4 (en) | 2020-03-11 |
| IL262903B (en) | 2019-08-29 |
| US10478159B2 (en) | 2019-11-19 |
| CN109152569A (zh) | 2019-01-04 |
| US20190175155A1 (en) | 2019-06-13 |
| SG11201809873UA (en) | 2018-12-28 |
| CN109152569B (zh) | 2021-06-22 |
| ES2963174T3 (es) | 2024-03-25 |
| US20170340352A1 (en) | 2017-11-30 |
| KR20190008953A (ko) | 2019-01-25 |
| CN113017795A (zh) | 2021-06-25 |
| EP3463101A1 (en) | 2019-04-10 |
| AU2017270207A1 (en) | 2018-12-13 |
| CA3023978A1 (en) | 2017-11-30 |
| IL262903A (en) | 2018-12-31 |
| JP2019523661A (ja) | 2019-08-29 |
| EP3463101B8 (en) | 2023-10-18 |
| WO2017205640A1 (en) | 2017-11-30 |
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